About the book
The tropical zebrafish is a versatile model organism that has been used in biomedical research to understand different mechanisms underlying of the problems in human diseases.
There are many technical advantages of using zebrafish such as fully sequenced genome, rapid embryonic development outside of the mother’s body, well-characterized behaviour (easy observation) and allowing detailed visualization of organs and cellular activity.
Zebrafish has been shown to be similar to mammalian biological models when it comes to toxicity tolerance and circadian rhythms. Also, it is capable of regenerating several tissues, like fins, heart, photoreceptor cells, retinal neurons and even spinal cord.
Furthermore zebrafish allows mapping of their brain networks which facilitates the study of human neurological diseases.
Finally, the tools available and the plasticity of this biological model allowed for the establishment of zebrafish as a human disease model for cancer, cardiovascular and immune system diseases, and many others.
This book will provide an overview of research in human medicine using zebrafish as model organism, discussing different aspects of their biology, ecology and nutrition.