About the book
Botulinum toxin is a type of neurotoxin produced by the bacterium Clostridium botulinum. It has eight different serotypes: A, B, C1, C2, D, E, F, and G. Its main mechanism of action is blocking the release of acetylcholine which is one of the main neurotransmitters at the neuromuscular junction, causing muscle paralysis. Botulinum toxins have significant therapeutic effects in different pathological conditions including cervical dystonia, glabellar facial lines, noninvasive facial aesthetic treatments, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, axillary hyperhidrosis, and chronic migraine. It is also used in cosmetic purposes. Injectable and topical formulations are present for botulinum toxins in medical use, and are approved by the FDA. The cosmetological applications for botulinum toxins include correction of lines, creases and wrinkling all over the face, chin, neck and chest, to dermatological applications.
This book aims to contribute to the future use of botulinum toxin by providing useful, extensive, and detailed information on the topic.