\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"2303",leadTitle:null,fullTitle:"Gel Electrophoresis - Advanced Techniques",title:"Gel Electrophoresis",subtitle:"Advanced Techniques",reviewType:"peer-reviewed",abstract:"As a basic concept, gel electrophoresis is a biotechnology technique in which macromolecules such as DNA, RNA or protein are fractionated according to their physical properties such as molecular weight or charge. These molecules are forced through a porous gel matrix under electric field enabling uncounted applications and uses. Delivered between your hands, a second book of this Gel electrophoresis series (Gel Electrophoresis- Advanced Techniques) covers a part, but not all, applications of this versatile technique in both medical and life science fields.\nWe try to keep the contents of the book crisp and comprehensive, and hope that it will receive overwhelming interest and deliver benefits and valuable information to the readers.",isbn:null,printIsbn:"978-953-51-0457-5",pdfIsbn:"978-953-51-5266-8",doi:"10.5772/2688",price:159,priceEur:175,priceUsd:205,slug:"gel-electrophoresis-advanced-techniques",numberOfPages:514,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"99b6af88dfcbe43d82dc7293184207c1",bookSignature:"Sameh Magdeldin",publishedDate:"April 4th 2012",coverURL:"https://cdn.intechopen.com/books/images_new/2303.jpg",numberOfDownloads:110704,numberOfWosCitations:43,numberOfCrossrefCitations:12,numberOfCrossrefCitationsByBook:2,numberOfDimensionsCitations:51,numberOfDimensionsCitationsByBook:2,hasAltmetrics:1,numberOfTotalCitations:106,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"May 26th 2011",dateEndSecondStepPublish:"June 23rd 2011",dateEndThirdStepPublish:"October 28th 2011",dateEndFourthStepPublish:"November 27th 2011",dateEndFifthStepPublish:"March 26th 2012",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"123648",title:"Dr.",name:"Sameh",middleName:null,surname:"Magdeldin",slug:"sameh-magdeldin",fullName:"Sameh Magdeldin",profilePictureURL:"https://mts.intechopen.com/storage/users/123648/images/475_n.jpg",biography:"Sameh Magdeldin is senior researcher in the Medical School,\nNiigata University, Japan, and academic associate professor in\nthe Physiology Department, Suez Canal University (SCU), Egypt.\nHe received his M.V.Sc. and Ph.D. in Physiology and his second\nPh.D. in Proteomics in July 2012. He has expertise in shotgun proteomics analysis, reversed-phase chromatography and label-free comparative proteomics\napproaches. Dr. Magdeldin has published outstanding articles on aquaporin research using proteomics technology. He also created the outstanding “All and\nNone” methodology for analyzing large-throughput proteomics data published\nin a highly respected proteomics journal. He currently serves as a guest editor,\nassociate editor and peer reviewer for several international journals. Dr. Magdeldin received several grants and awards, such as the national encouraging prize,\n8th HUPO congress young investigator award, JSN award, grant-in-aid for young\nscientists and young researcher overseas grant from the Japan Society for the\nPromotion of Science (JSPS).",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"5",institution:{name:"Niigata University",institutionURL:null,country:{name:"Japan"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"410",title:"Biotechnology",slug:"biochemistry-genetics-and-molecular-biology-microbiology-biotechnology"}],chapters:[{id:"34909",title:"Application of Gel Electrophoresis Techniques to the Study of Wine Yeast and to Improve Winemaking",doi:"10.5772/38548",slug:"application-of-gel-electrophoresis-techniques-to-the-study-of-wine-yeast-and-to-improve-winemaking",totalDownloads:3472,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"María Esther Rodríguez, Laureana Rebordinos, Eugenia Muñoz-Bernal, Francisco Javier Fernández-Acero and Jesús Manuel Cantoral",downloadPdfUrl:"/chapter/pdf-download/34909",previewPdfUrl:"/chapter/pdf-preview/34909",authors:[{id:"115954",title:"Prof.",name:"Jesús Manuel",surname:"Cantoral Fernández",slug:"jesus-manuel-cantoral-fernandez",fullName:"Jesús Manuel Cantoral Fernández"},{id:"117891",title:"Dr.",name:"Francisco Javier",surname:"Fernández-Acero",slug:"francisco-javier-fernandez-acero",fullName:"Francisco Javier Fernández-Acero"},{id:"117934",title:"Dr.",name:"Maria Esther",surname:"Rodríguez",slug:"maria-esther-rodriguez",fullName:"Maria Esther Rodríguez"},{id:"117936",title:"Prof.",name:"Laureana",surname:"Rebordinos",slug:"laureana-rebordinos",fullName:"Laureana Rebordinos"},{id:"117937",title:"MSc.",name:"Eugenia",surname:"Muñoz-Bernal",slug:"eugenia-munoz-bernal",fullName:"Eugenia Muñoz-Bernal"}],corrections:null},{id:"34910",title:"Proteomics in Seaweeds: Ecological Interpretations",doi:"10.5772/37965",slug:"proteomics-in-seaweeds-ecological-interpretations",totalDownloads:2911,totalCrossrefCites:2,totalDimensionsCites:6,hasAltmetrics:0,abstract:null,signatures:"Loretto Contreras-Porcia and Camilo López-Cristoffanini",downloadPdfUrl:"/chapter/pdf-download/34910",previewPdfUrl:"/chapter/pdf-preview/34910",authors:[{id:"114982",title:"Prof.",name:"Loretto",surname:"Contreras-Porcia",slug:"loretto-contreras-porcia",fullName:"Loretto Contreras-Porcia"}],corrections:null},{id:"34911",title:"Gel Electrophoresis Based Genetic Fingerprinting Techniques on Environmental Ecology",doi:"10.5772/37063",slug:"application-of-genetic-fingerprinting-techniques-on-environmental-ecology",totalDownloads:3984,totalCrossrefCites:1,totalDimensionsCites:3,hasAltmetrics:0,abstract:null,signatures:"Zeynep Cetecioglu, Orhan Ince and Bahar Ince",downloadPdfUrl:"/chapter/pdf-download/34911",previewPdfUrl:"/chapter/pdf-preview/34911",authors:[{id:"48845",title:"Prof.",name:"Orhan",surname:"Ince",slug:"orhan-ince",fullName:"Orhan Ince"},{id:"53263",title:"Dr.",name:"Zeynep",surname:"Cetecioglu",slug:"zeynep-cetecioglu",fullName:"Zeynep Cetecioglu"},{id:"56506",title:"Prof.",name:"Bahar",surname:"Ince",slug:"bahar-ince",fullName:"Bahar Ince"}],corrections:null},{id:"34912",title:"Gel Electrophoresis of Grapevine (Vitis vinifera L.) 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Fernández-Acero, María Carbú, Victoria E. González-Rodríguez, Eva Liñeiro and Jesús M. Cantoral",downloadPdfUrl:"/chapter/pdf-download/34916",previewPdfUrl:"/chapter/pdf-preview/34916",authors:[{id:"115954",title:"Prof.",name:"Jesús Manuel",surname:"Cantoral Fernández",slug:"jesus-manuel-cantoral-fernandez",fullName:"Jesús Manuel Cantoral Fernández"},{id:"117891",title:"Dr.",name:"Francisco Javier",surname:"Fernández-Acero",slug:"francisco-javier-fernandez-acero",fullName:"Francisco Javier Fernández-Acero"},{id:"117887",title:"Prof.",name:"Carlos",surname:"Garrido",slug:"carlos-garrido",fullName:"Carlos Garrido"},{id:"117892",title:"Dr.",name:"Maria",surname:"Carbú",slug:"maria-carbu",fullName:"Maria Carbú"},{id:"117893",title:"Dr.",name:"Victoria E.",surname:"González-Rodríguez",slug:"victoria-e.-gonzalez-rodriguez",fullName:"Victoria E. 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Rada",authors:[{id:"114650",title:"Dr",name:"Eugen",middleName:null,surname:"Culea",fullName:"Eugen Culea",slug:"eugen-culea"},{id:"114653",title:"Dr.",name:"Simona",middleName:null,surname:"Rada",fullName:"Simona Rada",slug:"simona-rada"}]},{id:"36169",title:"Water in Rocks and Minerals - Species, Distributions, and Temperature Dependences",slug:"water-in-rocks-and-minerals-species-distributions-and-temperature-dependences",signatures:"Jun-ichi Fukuda",authors:[{id:"105384",title:"Dr.",name:"Jun-Ichi",middleName:null,surname:"Fukuda",fullName:"Jun-Ichi Fukuda",slug:"jun-ichi-fukuda"}]},{id:"36170",title:"Attenuated Total Reflection - Infrared Spectroscopy Applied to the Study of Mineral - Aqueous Electrolyte Solution Interfaces: A General Overview and a Case Study",slug:"attenuated-total-reflection-infrared-spectroscopy-applied-to-the-study-of-mineral-aqueous-el",signatures:"Grégory Lefèvre, Tajana Preočanin and Johannes Lützenkirchen",authors:[{id:"108416",title:"Dr.",name:"Johannes",middleName:null,surname:"Lützenkirchen",fullName:"Johannes Lützenkirchen",slug:"johannes-lutzenkirchen"},{id:"111675",title:"Dr.",name:"Gregory",middleName:null,surname:"Lefevre",fullName:"Gregory Lefevre",slug:"gregory-lefevre"},{id:"111676",title:"Prof.",name:"Tajana",middleName:null,surname:"Preocanin",fullName:"Tajana Preocanin",slug:"tajana-preocanin"}]},{id:"36171",title:"Research of Calcium Phosphates Using Fourier Transform Infrared Spectroscopy",slug:"research-of-calcium-phosphates-using-fourier-transformation-infrared-spectroscopy",signatures:"Liga Berzina-Cimdina and Natalija Borodajenko",authors:[{id:"110522",title:"Prof.",name:"Liga",middleName:null,surname:"Berzina-Cimdina",fullName:"Liga Berzina-Cimdina",slug:"liga-berzina-cimdina"},{id:"112181",title:"MSc.",name:"Natalija",middleName:null,surname:"Borodajenko",fullName:"Natalija Borodajenko",slug:"natalija-borodajenko"}]},{id:"36172",title:"FTIR Spectroscopy of Adsorbed Probe Molecules for Analyzing the Surface Properties of Supported Pt (Pd) Catalysts",slug:"ftir-spectroscopy-of-adsorbed-probe-molecules-for-analyzing-the-surface-properties-of-supported-pt-p",signatures:"Olga B. 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One of the important early ideas is that of the Parzen window distribution [2]. It has been introduced in 1962, as a kernel density estimate of a distribution function underlying measured data, and still serves as the basis of clustering algorithms in pattern recognition [1, 3]. Recently, it has been discovered [4] that the Parzen probability function can be decomposed into two components, weight and shape, which represent different aspects of the data. Weight, as its name implies, describes the semi-global strength of the distribution, whereas shape represents local properties which come to light once the bias of the weight is being removed. Moreover, −log(shape) coincides with a potential function V, which has been previously introduced in quantum clustering (QC) [5]. The cluster centers in QC correspond to minima of V. An alternative method, mean shift [6, 7], views the maxima of the probability function as the appropriate candidates of cluster centers. These two different points of view can now be studied and compared within a unified formalism [4].
Here we discuss the novel connections of the Parzen distribution to its potential and show how both can be used for the analysis of data points, leading to alternative clustering possibilities and extracting interesting features from the data. A particularly interesting set of applications appears in image analysis. Scale-space image analysis [8] has developed from the Parzen kernel methodology discussed in [6]. Now it turns out that insights from the potential term, or the shape component, allow for novel applications which are relevant to medical and technical imaging.
Data analysis often involves dimensionality reduction and noise removal, as well as some other tools, which eventually lead to consider a set of preprocessed data points located in a d-dimensional Euclidean space
Following [4], we introduce a relative probability weight function representing the influence of the kernel at data point
It obeys
Their difference is related to the Parzen probability function
This can be rewritten as
using [4] the concepts of weight and shape:
Since
which has been the cornerstone of the QC algorithm [5].
All the scalar fields over data space, introduced in the previous section, depend on the parameter σ, the scale of all Gaussian kernels. This dependence leads to further interesting relations between the Parzen probability function and its potential. Thus, from the definitions (1) and (3), it follows that
where we keep the index σ which has been suppressed in the previous section. This relation displays a direct connection between the two scalar functions defining the probability and the potential. We proceed now to introduce a vector field
and vanishes when the probability reaches its extrema in data space. Interestingly it is also related to the gradient of the potential function, through
Hence we conclude that the potential reaches its extrema when
Its square
implies the existence of extrema of either the probability or the potential. Since
Although all extrema may be regarded as points of interest, some are of more interest than others: extrema that remain fixed in
Finally, we wish to point out that
where
This may be interpreted as a constraint on the expectation value of the potential function in data space.
Examples of the behavior of
(a) Loci of 9000 Galaxies, downloaded from the Sloan Digital Sky Server DR12, within some limited range of spherical angles. Reproduced from [
Figure 1 serves as an example of different behaviors of
A generally important question is if, within changing patterns of
Clustering methodologies based on maximization of the probability and minimization of the potential can be defined by letting replica of data points move in these directions. These methods are known as mean shift (MS) and quantum clustering (QC) correspondingly. A recent review of MS techniques has been presented in [11]. Analyzing the same data with the same width-parameter σ leads to different clustering results for these two different methods, as is expected from Figure 1.
For illustration of clustering based on these different methods, we consider the crab data set which is included in Ripley’s textbook [12]. It consists of 200 instances belonging to four equally sized classes and is defined in a five-dimensional parameter space. Performing PCA and restricting ourselves to the 2D plane defined by PC2-PC3 lead to a challenging clustering problem which has been discussed by [13], when introducing support vector clustering (SVC), and by [5] when introducing QC. It has been used in other papers employing variations of QC, such as the recent study [14]. Here we will show the results of [4] who applied to these data three clustering methods: Maximal Shape Clustering (MSC) which coincides with QC, Maximal Probability Clustering (MPC) which coincides with MS, and Maximal Entropy Clustering (MEC). The quality of all three methods may be judged by applying the Jaccard score
where n11 is the number of pairs of points which belong together both in the same class (accepted as “ground truth”) and in the same cluster, while n10 + n01 are numbers of pairs which belong to the same class but different clusters and vice versa. This test is performed in Figure 2a, demonstrating that QC wins the competition for a wide range of σ values. The expected asymptotic value is J = 98/398, befitting one cluster and four classes.
(a) The Jaccard score, comparing clustering results with expert classification, comparing three clustering methods over a range of σ values. (b) The number of clusters, for each method and value of σ. Reproduced from [
Another comparison is being made in Figure 2b. This follows Roberts’ criterion [9] that the preferable clustering method is the one which displays the most stable number of clusters with respect to variation of σ. This criterion is handy when the ground truth is unknown. QC excels also in this test, leading to a stable prediction of four clusters for a wide range of σ. This last figure also serve as a credibility test for Roberts’ criterion.
In order to make the clustering results more intuitive, we display in Figure 3, also taken from [4], topographic maps of the different fields describing probability, weight, and shape, for σ = 0.7. The points in four different colors represent the four different classes. The topographic maps allow one to understand the clustering results which represent the outcome of gradient ascent applied to replica of data points which climb toward their nearest peak. Comparing the topologies of Figure 3 with the results for σ = 0.7 in Figure 2 leads to an understanding of why the three methods differ from each other.
Topographic maps of probability, weight, and shape, for σ = 0.7. Reproduced from [
A gray-scale image may be analyzed as a set of inputs associated with different pixels. In higher dimensional problems, such as 3D MRI data, the pixels are replaced by voxels. Both may fit well into our analysis which starts with Eq. (1), associating a probability distribution with every image. One may then wonder if the weight-shape decomposition of Eq. (6)
can lead to any novel understanding of image analysis.
In any practical application, non-normalized probability and weight may have very large amplitudes, yet shape will be limited to values ≤1. Nonetheless it carries some important characteristics:
Shape may be normalized to become a distribution on its own.
Shape serves as a generalized edge detector.
Shape is the basis of QC; hence the latter is very relevant to clustering of regions where shape is large. Alternative methods may be relevant when shape is small.
The first claim is trivial since
To demonstrate the third point, we display in Figure 4 the results of an analysis of a T2 MRI of the brain of a Macaque monkey [15]. Following the general procedure outlined above, and limiting ourselves to large relative values (thresholded distributions) of probability and shape, we find that the latter peaks in cortical regions, whereas the former peaks in internal regions of the brain, as demonstrated in Figure 4. Thus, a simple thresholding procedure allows one to easily segment the MR image, for the purpose of further analysis of the cortex by applying QC to the data in the large
Thresholded shape (red) and thresholded probability (blue) dominate different regions within the same MR image of a macaque brain, projected on its y-z plane. This analysis used σ = 3 in voxel units. Data outside the brain are due to artifacts and noise in the MR image. These results are due to [
Characteristic results of QC cortical clusters as mapped onto the surface of the brain and projected onto the x-y plane. This figure displays a map of the largest clusters of shape, each described by a different color. These results are due to Fisher [
When one analyzes data in a regular underlying structure, such as pixels
with
where
Noting that Eq. (15) is reminiscent of a convolutional layer in a deep network [16], we hypothesize that it can be useful to incorporate intermediate layers with nonlinear filters such as Eq. (16), as additional non-trained pooling filters in deep networks.
The clustering methodology which has been employed in the different examples shown above is the simplest flavor of gradient descent (or ascent). It calculates the relevant fields on the basis of the data points and continues with straightforward dynamics that have been applied to replica of data points, seeking the extrema of the fields. Various alternatives to this basic application exist. The most important one is hierarchical clustering, which allows for conceptual simplicity and saves computational complexity. Such methodologies were described and discussed in [11] and in [4].
Computational complexity is an obvious issue when working with large data sets. Thus, 3D MRI data may easily comprise 1 M points, whereas their manipulation within a system like MATLAB may well be limited to handling only 40 K points at a time [15]. One way to overcome such issues is to consider performing the analysis within extended voxels, for example, voxels containing three pixels in each direction in a 3D image problem. Within each new voxel, one may simply sum the intensity of points, leading to a new presentation of the data in the form of Eq. 1 on the smaller extended voxel space. Clearly one has to make sure that such an approximation does not harm interesting features of the data.
When analyzing other big data, no prior dimensional representation may be required. For the sake of noise reduction and computational complexity, it is advantageous to first apply relevant dimensional reduction, as provided, for example, by singular value decomposition (SVD) and principal component analysis (PCA). It is also important to make sure that the different axes are of similar scale, as shown in the example of Figure 3. When the data is still large, one may apply the trick of extended voxels described above. For very large data, one may also separate the data into several components, as is customary in supervised learning, to make sure that conclusions are not affected by the random choice of a subset of the data.
In the past (see, e.g., [3]), Parzen analysis has not considered the potential field
Here we have defined a set of fields in data space which hopefully will turn out to serve as useful tools in future data analyses. They seem to be adequately applicable to image analysis, and we expect them to be particularly useful in biomedical and technical image analyses in three dimensions. When analyzing other data, where no visual display constraints exist, noise reduction and computational complexity call for preprocessing by dimensional reduction. Further reduction of computational complexity may be tried by employing extended voxels, which our technique can easily accommodate.
In summary, this extended Parzen method replaces any set of discreet data by a continuous set of fields in data space, with interrelations in scale space. It allows for investigating data properties in terms of these fields and their extrema.
This work has been partially supported by the Blavatnik Cyber Center of Tel Aviv University. I thank Itay Fisher for his help with numerical data analysis.
The author declares no conflict of interest.
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The majority of seed treatments are based on seed imbibition allowing the seeds to go through the first reversible stage of germination but do not allow radical protrusion through the seed coat. Seeds keeping their desiccation tolerance are then dehydrated and can be stored until final sowing. During subsequent germination, primed seeds exhibit a faster and more synchronized germination and young seedlings are often more vigorous and resistant to abiotic stresses than seedlings obtained from unprimed seeds. Priming often involves soaking seed in predetermined amounts of water or limitation of the imbibition time. The imbibition rate could be somehow controlled by osmotic agents such as PEG and referred as osmopriming. Halopriming implies the use of specific salts while "hormopriming" relies on the use of plant growth regulators. Some physical treatments (UV, cold or heat,..) also provide germination improvement thus suggesting that priming effects are not necessarily related to seed imbibition. A better understanding of the metabolic events taking place during the priming treatment and the subsequent germination should help to use this simple and cheap technology in a more efficient way.',book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Stanley Lutts, Paolo Benincasa, Lukasz Wojtyla, Szymon Kubala S,\nRoberta Pace, Katzarina Lechowska, Muriel Quinet and Malgorzata\nGarnczarska",authors:[{id:"94090",title:"Prof.",name:"Stanley",middleName:null,surname:"Lutts",slug:"stanley-lutts",fullName:"Stanley Lutts"},{id:"181730",title:"Prof.",name:"Paolo",middleName:null,surname:"Benincasa",slug:"paolo-benincasa",fullName:"Paolo Benincasa"},{id:"181732",title:"Dr.",name:"Lukasz",middleName:null,surname:"Wojtyla",slug:"lukasz-wojtyla",fullName:"Lukasz Wojtyla"},{id:"181733",title:"Dr.",name:"Szymon",middleName:null,surname:"Kubala",slug:"szymon-kubala",fullName:"Szymon Kubala"},{id:"181734",title:"Mrs.",name:"Katzzarina",middleName:null,surname:"Lechowska",slug:"katzzarina-lechowska",fullName:"Katzzarina Lechowska"},{id:"181735",title:"Dr.",name:"Muriel",middleName:null,surname:"Quinet",slug:"muriel-quinet",fullName:"Muriel Quinet"},{id:"181736",title:"Prof.",name:"Malgorzata",middleName:null,surname:"Garnczarska",slug:"malgorzata-garnczarska",fullName:"Malgorzata Garnczarska"}]},{id:"51881",doi:"10.5772/64791",title:"Recent Advances in Seed Enhancements",slug:"recent-advances-in-seed-enhancements",totalDownloads:4605,totalCrossrefCites:8,totalDimensionsCites:25,abstract:"Seed quality is vital to sustainable crop production and food security. Seed enhancements include physical, physiological and biological treatments to overcome germination constraints by uniform stands, earlier crop development and better yields. Improved germination rates and seedling vigour are due to reduced emergence time by earlier start of metabolic activities of hydrolytic enzymes and resource mobilization. Nutrient homeostasis, ion uptake, hormonal regulation, activation of antioxidant defence system, reduced lipid peroxidation and accumulation of compatible solutes are some mechanisms conferring biotic and abiotic stress tolerance. Several transcription factors for aquaporins, imbibitions, osmotic adjustment, antioxidant defence and phenylpropanoid pathway have been identified. However, the knowledge of molecular pathways elucidating mode of action of these effects, reduced longevity of primed or other physical and biological agents for seed treatments and market availability of high-quality seeds are some of the challenges for scientists and seed industry. In this scenario, there is need to minimize the factors associated with reduced vigour during seed production, improve seed storage and handling, develop high-tech seeds by seed industry at appropriate rates and integrate agronomic, physiological and molecular seed research for the effective regulation of high-quality seed delivery over next generations.",book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Irfan Afzal, Hafeez Ur Rehman, Muhammad Naveed and Shahzad\nMaqsood Ahmed Basra",authors:[{id:"180245",title:"Dr.",name:"Irfan",middleName:null,surname:"Afzal",slug:"irfan-afzal",fullName:"Irfan Afzal"}]},{id:"51743",doi:"10.5772/64466",title:"Effects of Some Hormone Applications on Germination and Morphological Characters of Endangered Plant Species Lilium artvinense L. Seeds",slug:"effects-of-some-hormone-applications-on-germination-and-morphological-characters-of-endangered-plant",totalDownloads:1803,totalCrossrefCites:3,totalDimensionsCites:9,abstract:"Lilies are economically important plants because of their large and attractive flowers. Thus, many wild species of lilies have been cultivated to produce Lilium bulbs or flowers. This work was conducted to analyse the effect of hormone applications on Lilium artvinense (Syn: Lilium ponticum K. Koch., Lilium ponticum var. artvinense (Miscz.) P. H. Davis and D. M. Hend., Lilium carniolicum var. artvinense (Miscz.) P. H. Davis and D. M. Hend and Lilium pyrenaicum var. artvinense (Miscz.) V.A. Matthews) seeds on germination percentage and seedlings morphological traits. In the research, 1000, 3000 and 5000 ppm doses of IAA, IBA, NAA and GA3 hormones were applied to L. artvinense seeds and approximately 180 days later, the number of roots, root length, offset stem height and diameter were assessed. As a result, while the control group except 5000 ppm NNA application achieved an increase in the percentage of germination (40%) of all the applications. Germination frequency up to 100% was obtained using 5000 ppm GA3. Effects of hormone applications on other key morphological characters (rooting percentage, root height, number of scions, scion height and width) are described in terms of growth rate between 1.27 and 2.44.",book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Kerim Guney, Mehmet Cetin, Hakan Sevik and Kudret Betül Güney",authors:[{id:"93082",title:"Dr.",name:"Hakan",middleName:null,surname:"Sevik",slug:"hakan-sevik",fullName:"Hakan Sevik"},{id:"166881",title:"Ph.D.",name:"Mehmet",middleName:null,surname:"Cetin",slug:"mehmet-cetin",fullName:"Mehmet Cetin"},{id:"181104",title:"Prof.",name:"Kerim",middleName:null,surname:"Guney",slug:"kerim-guney",fullName:"Kerim Guney"},{id:"181105",title:"Dr.",name:"Kudret Betül",middleName:null,surname:"Güney",slug:"kudret-betul-guney",fullName:"Kudret Betül Güney"}]},{id:"51923",doi:"10.5772/64085",title:"The Dynamics of Plant Cell Wall In Muro Modifications and its Physiological Implications on Seed Germination",slug:"the-dynamics-of-plant-cell-wall-in-muro-modifications-and-its-physiological-implications-on-seed-ger",totalDownloads:1219,totalCrossrefCites:4,totalDimensionsCites:6,abstract:"Seed germination is a complex process in which the embryo, enclosed within the surrounding tissues, must quickly switch from a maturation program to a germination‐driven developmental process that will prepare the embryo for seedling growth and establishment. The germination process initiates with water uptake by the dry seed and culminates, usually, with the radicle protrusion. The radicle emergence from the seed is a highly regulated process that involves discrete and coordinated changes in plant cell wall extensibility and rearrangements of its components, among other processes. In this chapter we will review current knowledge of the physiological process of controlled cell separation and expansion, which give the primary cell wall its plastic properties by “loosening” of the main components of the cell wall during seed germination. We will focus on the physiological importance of primary cell wall constitution and modification by the activity in muro of a broad variety of cell wall‐modifying enzymes that include hydrolases and transglycosylases, as well as non‐enzymatic processes such as expansin‐mediated loosening during seed germination.",book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Ximena Gómez‐Maqueo and Alicia Gamboa‐deBuen",authors:[{id:"115057",title:"Dr.",name:"Alicia",middleName:null,surname:"Gamboa-De Buen",slug:"alicia-gamboa-de-buen",fullName:"Alicia Gamboa-De Buen"},{id:"181871",title:"Ph.D. Student",name:"Ximena",middleName:null,surname:"Gómez-Maqueo",slug:"ximena-gomez-maqueo",fullName:"Ximena Gómez-Maqueo"}]},{id:"52197",doi:"10.5772/64994",title:"Postharvesting Techniques and Maintenance of Seed Quality",slug:"postharvesting-techniques-and-maintenance-of-seed-quality",totalDownloads:2871,totalCrossrefCites:2,totalDimensionsCites:5,abstract:"Healthy seeds and grains are the demanding enterprise of the recent era for the production of high yield in the next season. The seeds must be stored for the maintenance of high-yielding crop. During storage, major losses of seeds are caused by various biological and nonbiological factors. There is a need to examine reasonable factors of these crop losses, which ultimately affect the market value and quality of the seed. The quality of seeds can be maintained by using careful postharvest handling techniques. There is need to establish the well-suited methods to assess the losses during the process and to use the best technique to minimize the loss and to ensure the quality and safety of the crop. The target is to achieve the high-quality seeds of the national and international standards that could meet the demand of the supplier. This chapter emphasizes on the aspects and postharvest techniques that are used to maintain seed quality. A comprehensive review of the better, economical, convenient, and productive methods is provided, focused on the needs of developing countries but also with relevance in more industrialized countries.",book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Zubaida Yousaf, Nadia Saleh, Asba Ramazan and Arusa Aftab",authors:[{id:"180675",title:"Dr.",name:"Zubaida",middleName:null,surname:"Yousaf",slug:"zubaida-yousaf",fullName:"Zubaida Yousaf"}]}],mostDownloadedChaptersLast30Days:[{id:"51934",title:"Seed Priming: New Comprehensive Approaches for an Old Empirical Technique",slug:"seed-priming-new-comprehensive-approaches-for-an-old-empirical-technique",totalDownloads:7984,totalCrossrefCites:52,totalDimensionsCites:115,abstract:'Seed priming is a pre-sowing treatment which leads to a physiological state that enables seed to germinate more efficiently. The majority of seed treatments are based on seed imbibition allowing the seeds to go through the first reversible stage of germination but do not allow radical protrusion through the seed coat. Seeds keeping their desiccation tolerance are then dehydrated and can be stored until final sowing. During subsequent germination, primed seeds exhibit a faster and more synchronized germination and young seedlings are often more vigorous and resistant to abiotic stresses than seedlings obtained from unprimed seeds. Priming often involves soaking seed in predetermined amounts of water or limitation of the imbibition time. The imbibition rate could be somehow controlled by osmotic agents such as PEG and referred as osmopriming. Halopriming implies the use of specific salts while "hormopriming" relies on the use of plant growth regulators. Some physical treatments (UV, cold or heat,..) also provide germination improvement thus suggesting that priming effects are not necessarily related to seed imbibition. A better understanding of the metabolic events taking place during the priming treatment and the subsequent germination should help to use this simple and cheap technology in a more efficient way.',book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Stanley Lutts, Paolo Benincasa, Lukasz Wojtyla, Szymon Kubala S,\nRoberta Pace, Katzarina Lechowska, Muriel Quinet and Malgorzata\nGarnczarska",authors:[{id:"94090",title:"Prof.",name:"Stanley",middleName:null,surname:"Lutts",slug:"stanley-lutts",fullName:"Stanley Lutts"},{id:"181730",title:"Prof.",name:"Paolo",middleName:null,surname:"Benincasa",slug:"paolo-benincasa",fullName:"Paolo Benincasa"},{id:"181732",title:"Dr.",name:"Lukasz",middleName:null,surname:"Wojtyla",slug:"lukasz-wojtyla",fullName:"Lukasz Wojtyla"},{id:"181733",title:"Dr.",name:"Szymon",middleName:null,surname:"Kubala",slug:"szymon-kubala",fullName:"Szymon Kubala"},{id:"181734",title:"Mrs.",name:"Katzzarina",middleName:null,surname:"Lechowska",slug:"katzzarina-lechowska",fullName:"Katzzarina Lechowska"},{id:"181735",title:"Dr.",name:"Muriel",middleName:null,surname:"Quinet",slug:"muriel-quinet",fullName:"Muriel Quinet"},{id:"181736",title:"Prof.",name:"Malgorzata",middleName:null,surname:"Garnczarska",slug:"malgorzata-garnczarska",fullName:"Malgorzata Garnczarska"}]},{id:"52197",title:"Postharvesting Techniques and Maintenance of Seed Quality",slug:"postharvesting-techniques-and-maintenance-of-seed-quality",totalDownloads:2871,totalCrossrefCites:2,totalDimensionsCites:5,abstract:"Healthy seeds and grains are the demanding enterprise of the recent era for the production of high yield in the next season. The seeds must be stored for the maintenance of high-yielding crop. During storage, major losses of seeds are caused by various biological and nonbiological factors. There is a need to examine reasonable factors of these crop losses, which ultimately affect the market value and quality of the seed. The quality of seeds can be maintained by using careful postharvest handling techniques. There is need to establish the well-suited methods to assess the losses during the process and to use the best technique to minimize the loss and to ensure the quality and safety of the crop. The target is to achieve the high-quality seeds of the national and international standards that could meet the demand of the supplier. This chapter emphasizes on the aspects and postharvest techniques that are used to maintain seed quality. A comprehensive review of the better, economical, convenient, and productive methods is provided, focused on the needs of developing countries but also with relevance in more industrialized countries.",book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Zubaida Yousaf, Nadia Saleh, Asba Ramazan and Arusa Aftab",authors:[{id:"180675",title:"Dr.",name:"Zubaida",middleName:null,surname:"Yousaf",slug:"zubaida-yousaf",fullName:"Zubaida Yousaf"}]},{id:"51881",title:"Recent Advances in Seed Enhancements",slug:"recent-advances-in-seed-enhancements",totalDownloads:4605,totalCrossrefCites:8,totalDimensionsCites:25,abstract:"Seed quality is vital to sustainable crop production and food security. Seed enhancements include physical, physiological and biological treatments to overcome germination constraints by uniform stands, earlier crop development and better yields. Improved germination rates and seedling vigour are due to reduced emergence time by earlier start of metabolic activities of hydrolytic enzymes and resource mobilization. Nutrient homeostasis, ion uptake, hormonal regulation, activation of antioxidant defence system, reduced lipid peroxidation and accumulation of compatible solutes are some mechanisms conferring biotic and abiotic stress tolerance. Several transcription factors for aquaporins, imbibitions, osmotic adjustment, antioxidant defence and phenylpropanoid pathway have been identified. However, the knowledge of molecular pathways elucidating mode of action of these effects, reduced longevity of primed or other physical and biological agents for seed treatments and market availability of high-quality seeds are some of the challenges for scientists and seed industry. In this scenario, there is need to minimize the factors associated with reduced vigour during seed production, improve seed storage and handling, develop high-tech seeds by seed industry at appropriate rates and integrate agronomic, physiological and molecular seed research for the effective regulation of high-quality seed delivery over next generations.",book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Irfan Afzal, Hafeez Ur Rehman, Muhammad Naveed and Shahzad\nMaqsood Ahmed Basra",authors:[{id:"180245",title:"Dr.",name:"Irfan",middleName:null,surname:"Afzal",slug:"irfan-afzal",fullName:"Irfan Afzal"}]},{id:"51388",title:"Seed Germination Technologies for Helophyte Production Used in Wastewater Treatment",slug:"seed-germination-technologies-for-helophyte-production-used-in-wastewater-treatment",totalDownloads:1550,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"Constructed green wetlands with horizontal surface for wastewater treatment are gaining acceptance. Many countries have published innovative experiences with this technology. A great variety of wastewaters from industries have been treated. Different plant species have been tested. Seed technology development provides interesting tools to produce these species in nurseries. It is a sustainable new business. But studies on seed germination of aquatic and lacustrine plants are very few. That is why we have made the following bibliographic review. We have summarised and analysed the state of the art of this innovative topic, concluding that seed technology for multiplication of helophytes needs further experimental work. But there is enough information to produce right now, tens of different species. Significant efforts have been done. Even though it is a challenge to produce from now on, experimental results are ready to be transferred to those who are trading with this type of plants. Helophytes have a promising future as sustainable elements of the upcoming sewage equipment. Improvements on the biotechnology of these species are a worthwhile researching line. To this aim, the following revision is an essential compilation with which to begin.",book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Trinidad Ruiz-Téllez, Francisco M. Vázquez-Pardo, José Blanco-Salas\nand F. Javier Carbonell-Espín",authors:[{id:"180723",title:"Prof.",name:"Trinidad",middleName:null,surname:"Ruiz Téllez",slug:"trinidad-ruiz-tellez",fullName:"Trinidad Ruiz Téllez"},{id:"181957",title:"Dr.",name:"José",middleName:null,surname:"Blanco Salas",slug:"jose-blanco-salas",fullName:"José Blanco Salas"},{id:"181958",title:"Mr.",name:"Javier",middleName:null,surname:"Carbonell Espín",slug:"javier-carbonell-espin",fullName:"Javier Carbonell Espín"},{id:"181959",title:"Dr.",name:"Francisco María",middleName:null,surname:"Vázquez Pardo",slug:"francisco-maria-vazquez-pardo",fullName:"Francisco María Vázquez Pardo"}]},{id:"51642",title:"Designing Novel Breeding Strategies for Producing High-Oil Crops Based on a Molecular Understanding of Triacylglycerol Metabolism",slug:"designing-novel-breeding-strategies-for-producing-high-oil-crops-based-on-a-molecular-understanding-",totalDownloads:1793,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Seeds are storage organ in plants and main resource of plant oils to human civilization and the demand of plant oils are increasing yearly and expansion of the production capacity is an urgent issue worldwide. Thus, it is necessary to improve oil yields per unit area and generation of crops with high-oil content is needed. Arabidopsis thaliana plays a vital role in advancement of genetics and molecular biology in plant sciences. The forward and reverse genetic approaches with Arabidopsis have provided an overview of triacylglycerol metabolism. The elucidation of the overview contributes to understanding of spatiotemporal regulation of a metabolic flow of triacylglycerol metabolism in plant cell. This understanding sheds light on bottlenecks in triacylglycerol biosynthesis and provides novel clues for increasing seed triacylglycerol content. Recent advance in metabolic engineering approaches demonstrate several evidences that triacylglycerol metabolism is coordinated with other metabolisms. Most notably, triacylglycerol biosynthesis competes with biosynthesis of starch or seed storage proteins. These studies indicate that alterations of the metabolic pathways to avoid the competitions could be a novel concept for increasing seed oil content.",book:{id:"5218",slug:"new-challenges-in-seed-biology-basic-and-translational-research-driving-seed-technology",title:"New Challenges in Seed Biology",fullTitle:"New Challenges in Seed Biology - Basic and Translational Research Driving Seed Technology"},signatures:"Masatake Kanai, Shoji Mano, Makoto Hayashi and Mikio Nishimura",authors:[{id:"124407",title:"Dr.",name:"Shoji",middleName:null,surname:"Mano",slug:"shoji-mano",fullName:"Shoji Mano"},{id:"124408",title:"Dr.",name:"Mikio",middleName:null,surname:"Nishimura",slug:"mikio-nishimura",fullName:"Mikio Nishimura"},{id:"181879",title:"Dr.",name:"Masatake",middleName:null,surname:"Kanai",slug:"masatake-kanai",fullName:"Masatake Kanai"},{id:"181882",title:"Dr.",name:"Makoto",middleName:null,surname:"Hayashi",slug:"makoto-hayashi",fullName:"Makoto Hayashi"}]}],onlineFirstChaptersFilter:{topicId:"343",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. 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",coverUrl:"https://cdn.intechopen.com/series/covers/23.jpg",latestPublicationDate:"June 25th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:0,editor:{id:"280770",title:"Dr.",name:"Katherine K.M.",middleName:null,surname:"Stavropoulos",slug:"katherine-k.m.-stavropoulos",fullName:"Katherine K.M. Stavropoulos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRdFuQAK/Profile_Picture_2022-05-24T09:03:48.jpg",biography:"Katherine Stavropoulos received her BA in Psychology from Trinity College, in Connecticut, USA. Dr. Stavropoulos received her Ph.D. in Experimental Psychology from the University of California, San Diego. She completed her postdoctoral work at the Yale Child Study Center with Dr. James McPartland. Dr. Stavropoulos’ doctoral dissertation explored neural correlates of reward anticipation to social versus nonsocial stimuli in children with and without autism spectrum disorders (ASD). She has been a faculty member at the University of California, Riverside in the School of Education since 2016. Her research focuses on translational studies to explore the reward system in ASD, as well as how anxiety contributes to social challenges in ASD. She also investigates how behavioral interventions affect neural activity, behavior, and school performance in children with ASD. She is also involved in the diagnosis of children with ASD and is a licensed clinical psychologist in California. She is the Assistant Director of the SEARCH Center at UCR and is a Faculty member in the Graduate Program in Neuroscience.",institutionString:null,institution:{name:"University of California, Riverside",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:2,paginationItems:[{id:"89",title:"Education",coverUrl:"https://cdn.intechopen.com/series_topics/covers/89.jpg",isOpenForSubmission:!1,annualVolume:null,editor:{id:"260066",title:"Associate Prof.",name:"Michail",middleName:null,surname:"Kalogiannakis",slug:"michail-kalogiannakis",fullName:"Michail Kalogiannakis",profilePictureURL:"https://mts.intechopen.com/storage/users/260066/images/system/260066.jpg",biography:"Michail Kalogiannakis is an Associate Professor of the Department of Preschool Education, University of Crete, and an Associate Tutor at School of Humanities at the Hellenic Open University. He graduated from the Physics Department of the University of Crete and continued his post-graduate studies at the University Paris 7-Denis Diderot (D.E.A. in Didactic of Physics), University Paris 5-René Descartes-Sorbonne (D.E.A. in Science Education) and received his Ph.D. degree at the University Paris 5-René Descartes-Sorbonne (PhD in Science Education). His research interests include science education in early childhood, science teaching and learning, e-learning, the use of ICT in science education, games simulations, and mobile learning. He has published over 120 articles in international conferences and journals and has served on the program committees of numerous international conferences.",institutionString:"University of Crete",institution:{name:"University of Crete",institutionURL:null,country:{name:"Greece"}}},editorTwo:{id:"422488",title:"Dr.",name:"Maria",middleName:null,surname:"Ampartzaki",slug:"maria-ampartzaki",fullName:"Maria Ampartzaki",profilePictureURL:"https://mts.intechopen.com/storage/users/422488/images/system/422488.jpg",biography:"Dr Maria Ampartzaki is an Assistant Professor in Early Childhood Education in the Department of Preschool Education at the University of Crete. Her research interests include ICT in education, science education in the early years, inquiry-based and art-based learning, teachers’ professional development, action research, and the Pedagogy of Multiliteracies, among others. She has run and participated in several funded and non-funded projects on the teaching of Science, Social Sciences, and ICT in education. She also has the experience of participating in five Erasmus+ projects.",institutionString:"University of Crete",institution:{name:"University of Crete",institutionURL:null,country:{name:"Greece"}}},editorThree:null},{id:"90",title:"Human Development",coverUrl:"https://cdn.intechopen.com/series_topics/covers/90.jpg",isOpenForSubmission:!0,annualVolume:11974,editor:{id:"191040",title:"Dr.",name:"Tal",middleName:null,surname:"Dotan Ben-Soussan",slug:"tal-dotan-ben-soussan",fullName:"Tal Dotan Ben-Soussan",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBf1QAG/Profile_Picture_2022-03-18T07:56:11.jpg",biography:"Tal Dotan Ben-Soussan, Ph.D., is the director of the Research Institute for Neuroscience, Education and Didactics (RINED) – Paoletti Foundation. Ben-Soussan leads international studies on training and neuroplasticity from neurophysiological and psychobiological perspectives. As a neuroscientist and bio-psychologist, she has published numerous articles on neuroplasticity, movement and meditation. She acts as an editor and reviewer in several renowned journals and coordinates international conferences integrating theoretical, methodological and practical approaches on various topics, such as silence, logics and neuro-education. She lives in Assisi, Italy.",institutionString:"Research Institute for Neuroscience, Education and Didactics, Patrizio Paoletti Foundation",institution:null},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:10,paginationItems:[{id:"82380",title:"Evolution of Parasitism and Pathogenic Adaptations in Certain Medically Important Fungi",doi:"10.5772/intechopen.105206",signatures:"Gokul Shankar Sabesan, Ranjit Singh AJA, Ranjith Mehenderkar and Basanta Kumar Mohanty",slug:"evolution-of-parasitism-and-pathogenic-adaptations-in-certain-medically-important-fungi",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fungal Infectious Diseases - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11400.jpg",subseries:{id:"4",title:"Fungal Infectious Diseases"}}},{id:"82367",title:"Spatial Variation and Factors Associated with Unsuppressed HIV Viral Load among Women in an HIV Hyperendemic Area of KwaZulu-Natal, South Africa",doi:"10.5772/intechopen.105547",signatures:"Adenike O. Soogun, Ayesha B.M. Kharsany, Temesgen Zewotir and Delia North",slug:"spatial-variation-and-factors-associated-with-unsuppressed-hiv-viral-load-among-women-in-an-hiv-hype",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82193",title:"Enterococcal Infections: Recent Nomenclature and emerging trends",doi:"10.5772/intechopen.104792",signatures:"Kavita Raja",slug:"enterococcal-infections-recent-nomenclature-and-emerging-trends",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"82207",title:"Management Strategies in Perinatal HIV",doi:"10.5772/intechopen.105451",signatures:"Kayla Aleshire and Rima Bazzi",slug:"management-strategies-in-perinatal-hiv",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}}]},overviewPagePublishedBooks:{paginationCount:13,paginationItems:[{type:"book",id:"6667",title:"Influenza",subtitle:"Therapeutics and Challenges",coverURL:"https://cdn.intechopen.com/books/images_new/6667.jpg",slug:"influenza-therapeutics-and-challenges",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"105e347b2d5dbbe6b593aceffa051efa",volumeInSeries:1,fullTitle:"Influenza - Therapeutics and Challenges",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}]},{type:"book",id:"7064",title:"Current Perspectives in Human Papillomavirus",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7064.jpg",slug:"current-perspectives-in-human-papillomavirus",publishedDate:"May 2nd 2019",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"d92a4085627bab25ddc7942fbf44cf05",volumeInSeries:2,fullTitle:"Current Perspectives in Human Papillomavirus",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}]},{type:"book",id:"7123",title:"Current Topics in Neglected Tropical Diseases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7123.jpg",slug:"current-topics-in-neglected-tropical-diseases",publishedDate:"December 4th 2019",editedByType:"Edited by",bookSignature:"Alfonso J. Rodriguez-Morales",hash:"61c627da05b2ace83056d11357bdf361",volumeInSeries:3,fullTitle:"Current Topics in Neglected Tropical Diseases",editors:[{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. 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Presently he is working as a associate professor in the Dept of Prosthodontics, Rural Dental College, Loni and maintains a successful private practice specialising in Implantology at Rahata.\n\nEmail: drdeepak_mvikhe@yahoo.com..................",institutionString:null,institution:{name:"Pravara Institute of Medical Sciences",country:{name:"India"}}},{id:"204110",title:"Dr.",name:"Ahmed A.",middleName:null,surname:"Madfa",slug:"ahmed-a.-madfa",fullName:"Ahmed A. Madfa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204110/images/system/204110.jpg",biography:"Dr. Madfa is currently Associate Professor of Endodontics at Thamar University and a visiting lecturer at Sana'a University and University of Sciences and Technology. He has more than 6 years of experience in teaching. His research interests include root canal morphology, functionally graded concept, dental biomaterials, epidemiology and dental education, biomimetic restoration, finite element analysis and endodontic regeneration. Dr. Madfa has numerous international publications, full articles, two patents, a book and a book chapter. Furthermore, he won 14 international scientific awards. Furthermore, he is involved in many academic activities ranging from editorial board member, reviewer for many international journals and postgraduate students' supervisor. Besides, I deliver many courses and training workshops at various scientific events. Dr. Madfa also regularly attends international conferences and holds administrative positions (Deputy Dean of the Faculty for Students’ & Academic Affairs and Deputy Head of Research Unit).",institutionString:"Thamar University",institution:null},{id:"210472",title:"Dr.",name:"Nermin",middleName:"Mohammed Ahmed",surname:"Yussif",slug:"nermin-yussif",fullName:"Nermin Yussif",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210472/images/system/210472.jpg",biography:"Dr. Nermin Mohammed Ahmed Yussif is working at the Faculty of dentistry, University for October university for modern sciences and arts (MSA). Her areas of expertise include: periodontology, dental laserology, oral implantology, periodontal plastic surgeries, oral mesotherapy, nutrition, dental pharmacology. She is an editor and reviewer in numerous international journals.",institutionString:"MSA University",institution:null},{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. He is also a Member of the Reviewer Board of International Journal of Dental Medicine (IJDM), and the Indian Journal of Conservative and Endodontics since 2016.",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",country:{name:"India"}}},{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null},{id:"178412",title:"Associate Prof.",name:"Guhan",middleName:null,surname:"Dergin",slug:"guhan-dergin",fullName:"Guhan Dergin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178412/images/6954_n.jpg",biography:"Assoc. Prof. Dr. Gühan Dergin was born in 1973 in Izmit. He graduated from Marmara University Faculty of Dentistry in 1999. He completed his specialty of OMFS surgery in Marmara University Faculty of Dentistry and obtained his PhD degree in 2006. In 2005, he was invited as a visiting doctor in the Oral and Maxillofacial Surgery Department of the University of North Carolina, USA, where he went on a scholarship. Dr. Dergin still continues his academic career as an associate professor in Marmara University Faculty of Dentistry. He has many articles in international and national scientific journals and chapters in books.",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"178414",title:"Prof.",name:"Yusuf",middleName:null,surname:"Emes",slug:"yusuf-emes",fullName:"Yusuf Emes",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178414/images/6953_n.jpg",biography:"Born in Istanbul in 1974, Dr. Emes graduated from Istanbul University Faculty of Dentistry in 1997 and completed his PhD degree in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery in 2005. He has papers published in international and national scientific journals, including research articles on implantology, oroantral fistulas, odontogenic cysts, and temporomandibular disorders. Dr. Emes is currently working as a full-time academic staff in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery.",institutionString:null,institution:{name:"Istanbul University",country:{name:"Turkey"}}},{id:"192229",title:"Ph.D.",name:"Ana Luiza",middleName:null,surname:"De Carvalho Felippini",slug:"ana-luiza-de-carvalho-felippini",fullName:"Ana Luiza De Carvalho Felippini",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192229/images/system/192229.jpg",biography:null,institutionString:"University of São Paulo",institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"256851",title:"Prof.",name:"Ayşe",middleName:null,surname:"Gülşen",slug:"ayse-gulsen",fullName:"Ayşe Gülşen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256851/images/9696_n.jpg",biography:"Dr. Ayşe Gülşen graduated in 1990 from Faculty of Dentistry, University of Ankara and did a postgraduate program at University of Gazi. \nShe worked as an observer and research assistant in Craniofacial Surgery Departments in New York, Providence Hospital in Michigan and Chang Gung Memorial Hospital in Taiwan. \nShe works as Craniofacial Orthodontist in Department of Aesthetic, Plastic and Reconstructive Surgery, Faculty of Medicine, University of Gazi, Ankara Turkey since 2004.",institutionString:"Univeristy of Gazi",institution:null},{id:"255366",title:"Prof.",name:"Tosun",middleName:null,surname:"Tosun",slug:"tosun-tosun",fullName:"Tosun Tosun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255366/images/7347_n.jpg",biography:"Graduated at the Faculty of Dentistry, University of Istanbul, Turkey in 1989;\nVisitor Assistant at the University of Padua, Italy and Branemark Osseointegration Center of Treviso, Italy between 1993-94;\nPhD thesis on oral implantology in University of Istanbul and was awarded the academic title “Dr.med.dent.”, 1997;\nHe was awarded the academic title “Doç.Dr.” (Associated Professor) in 2003;\nProficiency in Botulinum Toxin Applications, Reading-UK in 2009;\nMastership, RWTH Certificate in Laser Therapy in Dentistry, AALZ-Aachen University, Germany 2009-11;\nMaster of Science (MSc) in Laser Dentistry, University of Genoa, Italy 2013-14.\n\nDr.Tosun worked as Research Assistant in the Department of Oral Implantology, Faculty of Dentistry, University of Istanbul between 1990-2002. \nHe worked part-time as Consultant surgeon in Harvard Medical International Hospitals and John Hopkins Medicine, Istanbul between years 2007-09.\u2028He was contract Professor in the Department of Surgical and Diagnostic Sciences (DI.S.C.), Medical School, University of Genova, Italy between years 2011-16. \nSince 2015 he is visiting Professor at Medical School, University of Plovdiv, Bulgaria. \nCurrently he is Associated Prof.Dr. at the Dental School, Oral Surgery Dept., Istanbul Aydin University and since 2003 he works in his own private clinic in Istanbul, Turkey.\u2028\nDr.Tosun is reviewer in journal ‘Laser in Medical Sciences’, reviewer in journal ‘Folia Medica\\', a Fellow of the International Team for Implantology, Clinical Lecturer of DGZI German Association of Oral Implantology, Expert Lecturer of Laser&Health Academy, Country Representative of World Federation for Laser Dentistry, member of European Federation of Periodontology, member of Academy of Laser Dentistry. Dr.Tosun presents papers in international and national congresses and has scientific publications in international and national journals. He speaks english, spanish, italian and french.",institutionString:null,institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",biography:"Zühre Akarslan was born in 1977 in Cyprus. She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"256417",title:"Associate Prof.",name:"Sanaz",middleName:null,surname:"Sadry",slug:"sanaz-sadry",fullName:"Sanaz Sadry",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256417/images/8106_n.jpg",biography:null,institutionString:null,institution:null},{id:"272237",title:"Dr.",name:"Pinar",middleName:"Kiymet",surname:"Karataban",slug:"pinar-karataban",fullName:"Pinar Karataban",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/272237/images/8911_n.png",biography:"Assist.Prof.Dr.Pınar Kıymet Karataban, DDS PhD \n\nDr.Pınar Kıymet Karataban was born in Istanbul in 1975. After her graduation from Marmara University Faculty of Dentistry in 1998 she started her PhD in Paediatric Dentistry focused on children with special needs; mainly children with Cerebral Palsy. She finished her pHD thesis entitled \\'Investigation of occlusion via cast analysis and evaluation of dental caries prevalance, periodontal status and muscle dysfunctions in children with cerebral palsy” in 2008. She got her Assist. Proffessor degree in Istanbul Aydın University Paediatric Dentistry Department in 2015-2018. ın 2019 she started her new career in Bahcesehir University, Istanbul as Head of Department of Pediatric Dentistry. In 2020 she was accepted to BAU International University, Batumi as Professor of Pediatric Dentistry. She’s a lecturer in the same university meanwhile working part-time in private practice in Ege Dental Studio (https://www.egedisklinigi.com/) a multidisciplinary dental clinic in Istanbul. Her main interests are paleodontology, ancient and contemporary dentistry, oral microbiology, cerebral palsy and special care dentistry. She has national and international publications, scientific reports and is a member of IAPO (International Association for Paleodontology), IADH (International Association of Disability and Oral Health) and EAPD (European Association of Pediatric Dentistry).",institutionString:null,institution:null},{id:"202198",title:"Dr.",name:"Buket",middleName:null,surname:"Aybar",slug:"buket-aybar",fullName:"Buket Aybar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202198/images/6955_n.jpg",biography:"Buket Aybar, DDS, PhD, was born in 1971. She graduated from Istanbul University, Faculty of Dentistry, in 1992 and completed her PhD degree on Oral and Maxillofacial Surgery in Istanbul University in 1997.\nDr. Aybar is currently a full-time professor in Istanbul University, Faculty of Dentistry Department of Oral and Maxillofacial Surgery. She has teaching responsibilities in graduate and postgraduate programs. Her clinical practice includes mainly dentoalveolar surgery.\nHer topics of interest are biomaterials science and cell culture studies. She has many articles in international and national scientific journals and chapters in books; she also has participated in several scientific projects supported by Istanbul University Research fund.",institutionString:null,institution:null},{id:"260116",title:"Dr.",name:"Mehmet",middleName:null,surname:"Yaltirik",slug:"mehmet-yaltirik",fullName:"Mehmet Yaltirik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/260116/images/7413_n.jpg",biography:"Birth Date 25.09.1965\r\nBirth Place Adana- Turkey\r\nSex Male\r\nMarrial Status Bachelor\r\nDriving License Acquired\r\nMother Tongue Turkish\r\n\r\nAddress:\r\nWork:University of Istanbul,Faculty of Dentistry, Department of Oral Surgery and Oral Medicine 34093 Capa,Istanbul- TURKIYE",institutionString:null,institution:null},{id:"172009",title:"Dr.",name:"Fatma Deniz",middleName:null,surname:"Uzuner",slug:"fatma-deniz-uzuner",fullName:"Fatma Deniz Uzuner",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/172009/images/7122_n.jpg",biography:"Dr. Deniz Uzuner was born in 1969 in Kocaeli-TURKEY. After graduating from TED Ankara College in 1986, she attended the Hacettepe University, Faculty of Dentistry in Ankara. \nIn 1993 she attended the Gazi University, Faculty of Dentistry, Department of Orthodontics for her PhD education. After finishing the PhD education, she worked as orthodontist in Ankara Dental Hospital under the Turkish Government, Ministry of Health and in a special Orthodontic Clinic till 2011. Between 2011 and 2016, Dr. Deniz Uzuner worked as a specialist in the Department of Orthodontics, Faculty of Dentistry, Gazi University in Ankara/Turkey. In 2016, she was appointed associate professor. Dr. Deniz Uzuner has authored 23 Journal Papers, 3 Book Chapters and has had 39 oral/poster presentations. She is a member of the Turkish Orthodontic Society. Her knowledge of English is at an advanced level.",institutionString:null,institution:null},{id:"332914",title:"Dr.",name:"Muhammad Saad",middleName:null,surname:"Shaikh",slug:"muhammad-saad-shaikh",fullName:"Muhammad Saad Shaikh",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Jinnah Sindh Medical University",country:{name:"Pakistan"}}},{id:"315775",title:"Dr.",name:"Feng",middleName:null,surname:"Luo",slug:"feng-luo",fullName:"Feng Luo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sichuan University",country:{name:"China"}}},{id:"423519",title:"Dr.",name:"Sizakele",middleName:null,surname:"Ngwenya",slug:"sizakele-ngwenya",fullName:"Sizakele Ngwenya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419270",title:"Dr.",name:"Ann",middleName:null,surname:"Chianchitlert",slug:"ann-chianchitlert",fullName:"Ann Chianchitlert",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419271",title:"Dr.",name:"Diane",middleName:null,surname:"Selvido",slug:"diane-selvido",fullName:"Diane Selvido",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419272",title:"Dr.",name:"Irin",middleName:null,surname:"Sirisoontorn",slug:"irin-sirisoontorn",fullName:"Irin Sirisoontorn",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"355660",title:"Dr.",name:"Anitha",middleName:null,surname:"Mani",slug:"anitha-mani",fullName:"Anitha Mani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"355612",title:"Dr.",name:"Janani",middleName:null,surname:"Karthikeyan",slug:"janani-karthikeyan",fullName:"Janani Karthikeyan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"334400",title:"Dr.",name:"Suvetha",middleName:null,surname:"Siva",slug:"suvetha-siva",fullName:"Suvetha Siva",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}}]}},subseries:{item:{id:"11",type:"subseries",title:"Cell Physiology",keywords:"Neurodevelopment and Neurodevelopmental Disease, Free Radicals, Tumor Metastasis, Antioxidants, Essential Fatty Acids, Melatonin, Lipid Peroxidation Products and Aging Physiology",scope:"\r\n\tThe integration of tissues and organs throughout the mammalian body, as well as the expression, structure, and function of molecular and cellular components, is essential for modern physiology. The following concerns will be addressed in this Cell Physiology subject, which will consider all organ systems (e.g., brain, heart, lung, liver; gut, kidney, eye) and their interactions: (1) Neurodevelopment and Neurodevelopmental Disease (2) Free Radicals (3) Tumor Metastasis (4) Antioxidants (5) Essential Fatty Acids (6) Melatonin and (7) Lipid Peroxidation Products and Aging Physiology.
",coverUrl:"https://cdn.intechopen.com/series_topics/covers/11.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11407,editor:{id:"133493",title:"Prof.",name:"Angel",middleName:null,surname:"Catala",slug:"angel-catala",fullName:"Angel Catala",profilePictureURL:"https://mts.intechopen.com/storage/users/133493/images/3091_n.jpg",biography:"Prof. Dr. Angel Catalá \r\nShort Biography Angel Catalá was born in Rodeo (San Juan, Argentina). He studied \r\nchemistry at the Universidad Nacional de La Plata, Argentina, where received aPh.D. degree in chemistry (Biological Branch) in 1965. From\r\n1964 to 1974, he worked as Assistant in Biochemistry at the School of MedicineUniversidad Nacional de La Plata, Argentina. From 1974 to 1976, he was a Fellowof the National Institutes of Health (NIH) at the University of Connecticut, Health Center, USA. From 1985 to 2004, he served as a Full Professor oBiochemistry at the Universidad Nacional de La Plata, Argentina. He is Member ofthe National Research Council (CONICET), Argentina, and Argentine Society foBiochemistry and Molecular Biology (SAIB). His laboratory has been interested for manyears in the lipid peroxidation of biological membranes from various tissues and different species. Professor Catalá has directed twelve doctoral theses, publishedover 100 papers in peer reviewed journals, several chapters in books andtwelve edited books. Angel Catalá received awards at the 40th InternationaConference Biochemistry of Lipids 1999: Dijon (France). W inner of the Bimbo PanAmerican Nutrition, Food Science and Technology Award 2006 and 2012, South AmericaHuman Nutrition, Professional Category. 2006 award in pharmacology, Bernardo\r\nHoussay, in recognition of his meritorious works of research. Angel Catalá belongto the Editorial Board of Journal of lipids, International Review of Biophysical ChemistryFrontiers in Membrane Physiology and Biophysics, World Journal oExperimental Medicine and Biochemistry Research International, W orld Journal oBiological Chemistry, Oxidative Medicine and Cellular Longevity, Diabetes and thePancreas, International Journal of Chronic Diseases & Therapy, International Journal oNutrition, Co-Editor of The Open Biology Journal.",institutionString:null,institution:{name:"National University of La Plata",institutionURL:null,country:{name:"Argentina"}}},editorTwo:null,editorThree:null,series:{id:"10",title:"Physiology",doi:"10.5772/intechopen.72796",issn:"2631-8261"},editorialBoard:[{id:"186048",title:"Prof.",name:"Ines",middleName:null,surname:"Drenjančević",slug:"ines-drenjancevic",fullName:"Ines Drenjančević",profilePictureURL:"https://mts.intechopen.com/storage/users/186048/images/5818_n.jpg",institutionString:null,institution:{name:"University of Osijek",institutionURL:null,country:{name:"Croatia"}}},{id:"187859",title:"Prof.",name:"Kusal",middleName:"K.",surname:"Das",slug:"kusal-das",fullName:"Kusal Das",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBDeQAO/Profile_Picture_1623411145568",institutionString:"BLDE (Deemed to be University), India",institution:null},{id:"79615",title:"Dr.",name:"Robson",middleName:null,surname:"Faria",slug:"robson-faria",fullName:"Robson Faria",profilePictureURL:"https://mts.intechopen.com/storage/users/79615/images/system/79615.png",institutionString:null,institution:{name:"Oswaldo Cruz Foundation",institutionURL:null,country:{name:"Brazil"}}},{id:"84459",title:"Prof.",name:"Valerie",middleName:null,surname:"Chappe",slug:"valerie-chappe",fullName:"Valerie Chappe",profilePictureURL:"https://mts.intechopen.com/storage/users/84459/images/system/84459.jpg",institutionString:null,institution:{name:"Dalhousie University",institutionURL:null,country:{name:"Canada"}}}]},onlineFirstChapters:{paginationCount:26,paginationItems:[{id:"82112",title:"Comparative Senescence and Lifespan",doi:"10.5772/intechopen.105137",signatures:"Hassan M. 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