Antonio Sillero

Spanish National Research CouncilSpain

ANTONIO SILLERO (Short Curriculum vitae) Present Position: Emeritus Professor Departamento de Bioquimica Facultad de Medicina Universidad Autonoma de Madrid (UAM) Arzobispo Morcillo, 4, 28029 Madrid. Spain. Tel. 34 914975413. FAX 34 91-5854401 Birth Place: Rute (Cordoba), Spain Birth Date: January 13, 1938 Nationality: Spanish Education 1955-62 Medical studies, Universidad de Granada. 1958-63 Chemical studies. Universidad de Granada 1963-67 Training in the Maranon Intitute of Consejo Superior Investigaciones Cientificas (CSIC): Thyroid Studies Unit (1963-64) under the supervision of Drs. Escobar. Enzymology Unit (1964-67) under the supervision of Dr. A. Sols 1967 Ph. D. in Chemistry. Universidad Complutense de Madrid. 1967 M.D. Ph. D. Universidad de Granada 1967-70 Postdoctoral training in the Department of Biochemistry. New York University School of Medicine under the supervision of Dr. S. Ochoa Positions held 1964-67 Fellow of the Ministry of Science and Education 1967-69 Fellow of National Institutes of Health (USA). 1969-70 Fellow of the Jane Coffin Childs Memorial Fund (USA). 1968-70 Ayudante de Investigacion (CSIC). 1970-73 Colaborador Cientifico (CSIC). 1973-75 Investigador Cientifico (CSIC). 1974-75 Chief Enzyme Biosynthesis Unit of the Instituto de Enzimologia (CSIC). 1975-78 Associate Professor of Physiology and Biochemistry. Facultad de Medicina. Universidad de Valladolid. 1978-79 Associate Professor of Biochemistry. Facultad de Medicina UAM 1979-87 Full Professor of Biochemistry and Molecular Biology. Facultad de Medicina. Universidad de Extremadura (UNEX). 1979-87 Director Departament of Biochemistry and Molecular Biology (UNEX) 1980-81 Director Institute of Educational Sciences. UNEX. 1981-83 Vicerector of UNEX. 1987-2008 Full Professor of Biochemistry and Molecular Biology. Facultad de Medicina. UAM. 1996-99 Director Department of Enzimolgy and Molecular Pathology. Institute of Biomedical Research. CSIC 2002-2005 Director Departament of Biochemistry. Facultad de Medicina. Universidad Autonoma de Madrid 2008- Emeritus Professor Research Projects and Scientific Activities 1964-67 Regulation of glucokinase, hexokinase, and other irreversible enzymes of glucolysis and gluconeogenesis in rat liver. Metabolism of fructose. 1967-70 Proteins of Bacteriophage Qbeta. Development of the crustacean Artemia. 1970-75 Development of the crustacean Artemia. Proteases. 1975-79 Development of the crustacean Artemia. Hydrolityc activities on dinucleoside polyphosphates. 1979-85 Interconversion of purine nucleotides. Metabolism and function of dinucleoside polyphosphates. 1985 Metabolites present at very low concentration in liver and other tissues 1985-2011 Theoretical determination of the electric charge and isoelectric point of macromoecules bearing acid-base goups.Electric charge and isoelectric point 1986-2011 Computer simulation of enzyme kinetics 1988-95 Role of dinucleoside polyphosphates in bovine adrenal medulla. 1989-2008 Mechanism of synthesis of dinucleoside polyphosphates 2006-2011 Mechanism of action of bisphosphonates 1970-2008 Grants from Jane Coffin Child Memorial Fund, Fundacion Juan March, Fundacion Ramón Areces, Comunidad de Madrid, Spanish Ministry of Health, and Spanish Ministry of Education and Science. 1977-98 Director of more than 12 Doctoral Courses in Spanish Universities, and 3 theoretical-practical courses on Clinical Enzymology in Oporto University (Portugal). 1975-2010 Director of 19 Doctoral Theses. 1968-2008 Member: Spanish Society of Biochemistry and Molecular Biology, Spanish Society of Physiology, Portuguese Society of Biochemistry, New York Academy of Sciences 1964-2011 More than 130 publications in International Journals.

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