The major indications for total knee arthroplasty
\r\n\t
",isbn:"978-1-83962-366-0",printIsbn:"978-1-83962-365-3",pdfIsbn:"978-1-83962-367-7",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"f7602ad192ad1dc79a6a37ce3b461769",bookSignature:"Prof. Hechmi Toumi and Dr. Eric Lespessailles",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11720.jpg",keywords:"Xray, MRI, Arthroscopy, Nonsteroidal Anti-inflammatory Drugs, Steroid Injections, Surgery, Muscle, Obesity, Age, Inflammation, Plants, Herbs",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 13th 2022",dateEndSecondStepPublish:"May 11th 2022",dateEndThirdStepPublish:"July 10th 2022",dateEndFourthStepPublish:"September 28th 2022",dateEndFifthStepPublish:"November 27th 2022",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"2 months",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Professor Hechmi Toumi is a researcher, and scientific director of the Transitional Medical Research PRIMMO, CHR Hospital Orleans. His research focuses on Bone, Cartilage, and soft tissue injuries. He has lectured worldwide on the Treatment and Prevention of muscular-skeletal injuries. He is the inventor of the international patent filing on the use of algorithmic analyses to identify and quantify ‘invisible’ detail in soft tissues in standard radiographs.",coeditorOneBiosketch:"Dr. Eric Lespessailles is a Medical Doctor in Rheumatology at the Regional Hospital of Orleans in France. He was awarded a Professorial title by CNU France (Conseil National Universitaire, section 66) in 2019. Eric is currently the medical director of the Translational Medicine Research Platform at the Regional Hospital of Orleans. He has published about 200 peer-reviewed manuscripts. His research focuses on osteoporosis, osteoarthritis, psoriatic arthritis, and musculoskeletal imaging.",coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"196403",title:"Prof.",name:"Hechmi",middleName:null,surname:"Toumi",slug:"hechmi-toumi",fullName:"Hechmi Toumi",profilePictureURL:"https://mts.intechopen.com/storage/users/196403/images/system/196403.png",biography:"Professor Hechmi Toumi graduated from Blaise Pascal University in France. He is a research assistant at the University of Wisconsin in the USA and at Cardiff University and is an awarded professor at the University of Wales, UK. He has acted as dean of the Faculty of Sciences at the University of Orleans from 2013 to 2020. Currently, Professor Toumi is the scientific director of Translational Medical Research Platform, PRIMMO, at the Orleans Hospital in France and vice president of the Institute of Research, Treatment, and Prevention of Osteoporosis. He is currently filing for an international patent application for his invention on the use of algorithmic analyses to identify and quantify invisible detail in soft tissues using standard radiographs. Professor Toumi has lectured worldwide on the pathologies, treatment, and prevention of muscular-skeletal injuries.",institutionString:"University of Orléans",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"University of Orléans",institutionURL:null,country:{name:"France"}}}],coeditorOne:{id:"379966",title:"Dr.",name:"Eric",middleName:null,surname:"Lespessailles",slug:"eric-lespessailles",fullName:"Eric Lespessailles",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:"Dr. Eric Lespessailles is a Medical Doctor in Rheumatology at the Regional Hospital of Orleans in France. Eric obtained a Ph.D. in Sciences in 2009. He was awarded a Professorial title by CNU France (Conseil National Universitaire, section 66) in 2019. Eric is currently the medical director of the Translational Medicine Research Platform at the Regional Hospital of Orleans. He has published about 200 peer-reviewed manuscripts. His research focuses on osteoporosis, osteoarthritis, psoriatic arthritis, and musculoskeletal imaging.",institutionString:"University of Orléans",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"0",institution:null},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"16",title:"Medicine",slug:"medicine"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"429341",firstName:"Paula",lastName:"Gavran",middleName:null,title:"Ms.",imageUrl:"//cdnintech.com/web/frontend/www/assets/author.svg",email:"paula@intechopen.com",biography:null}},relatedBooks:[{type:"book",id:"7565",title:"Osteoarthritis Biomarkers and Treatments",subtitle:null,isOpenForSubmission:!1,hash:"e1f50f84936fc4164de08483e43acc16",slug:"osteoarthritis-biomarkers-and-treatments",bookSignature:"Hechmi Toumi and Marija Mazor",coverURL:"https://cdn.intechopen.com/books/images_new/7565.jpg",editedByType:"Edited by",editors:[{id:"196403",title:"Prof.",name:"Hechmi",surname:"Toumi",slug:"hechmi-toumi",fullName:"Hechmi Toumi"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11031",title:"Rheumatoid Arthritis",subtitle:null,isOpenForSubmission:!1,hash:"b27b90045995c761c0d2f975e895c5d4",slug:"rheumatoid-arthritis",bookSignature:"Hechmi Toumi",coverURL:"https://cdn.intechopen.com/books/images_new/11031.jpg",editedByType:"Edited by",editors:[{id:"196403",title:"Prof.",name:"Hechmi",surname:"Toumi",slug:"hechmi-toumi",fullName:"Hechmi Toumi"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6550",title:"Cohort Studies in Health Sciences",subtitle:null,isOpenForSubmission:!1,hash:"01df5aba4fff1a84b37a2fdafa809660",slug:"cohort-studies-in-health-sciences",bookSignature:"R. Mauricio Barría",coverURL:"https://cdn.intechopen.com/books/images_new/6550.jpg",editedByType:"Edited by",editors:[{id:"88861",title:"Dr.",name:"R. Mauricio",surname:"Barría",slug:"r.-mauricio-barria",fullName:"R. Mauricio Barría"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9500",title:"Recent Advances in Bone Tumours and Osteoarthritis",subtitle:null,isOpenForSubmission:!1,hash:"ea4ec0d6ee01b88e264178886e3210ed",slug:"recent-advances-in-bone-tumours-and-osteoarthritis",bookSignature:"Hiran Amarasekera",coverURL:"https://cdn.intechopen.com/books/images_new/9500.jpg",editedByType:"Edited by",editors:[{id:"67634",title:"Dr.",name:"Hiran",surname:"Amarasekera",slug:"hiran-amarasekera",fullName:"Hiran Amarasekera"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2270",title:"Fourier Transform",subtitle:"Materials Analysis",isOpenForSubmission:!1,hash:"5e094b066da527193e878e160b4772af",slug:"fourier-transform-materials-analysis",bookSignature:"Salih Mohammed Salih",coverURL:"https://cdn.intechopen.com/books/images_new/2270.jpg",editedByType:"Edited by",editors:[{id:"111691",title:"Dr.Ing.",name:"Salih",surname:"Salih",slug:"salih-salih",fullName:"Salih Salih"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"43073",title:"Preoperative Planning of Total Knee Replacement",doi:"10.5772/55023",slug:"preoperative-planning-of-total-knee-replacement",body:'Total knee replacement (TKR) surgery is the gold standard method in the treatment of end stage knee arthritis with a high success. Relieving pain effectively, restoring range of motion and improving function are the major goals of arthroplasy. Patient satisfaction rates were reported as 90% to 95% after TKR. [1-3] Better clinical results were gained in younger population than the older patients. Unfortunately, primary osteoarthritis is seen mainly in the elderly. However, inflamatory arthritis, trauma, avascular necrosis and hemophilia are some of the secondary causes leading osteoarthritis in younger population.. Nearly 1 million TKR surgeries are performed on earth per year and this number is increasing day by day, with the novel designed surface technologies. Despite the fact that new implant technologies secure better results, a revision procedure may be required in some of the patients. Ofcourse the amount of revision surgeries is also increasing in parallel with primary TKR surgeries. Unfortunately, the clinical result of revision total knee arthroplasty isn’t succesfull enough as primary total knee arthroplasty.
Polyethylene (PE) wear, aseptic loosening, instability and infections are counted among the factors leading revision surgery [4,5]. The incidence of PE wear is decreased nowadays by the development of ultra high cross-linked polyethilens (UHMWPE). PE wear is a serious problem leading to aseptic loosening. Malalingment, malrotation and soft tissue imbalance after TKR surgery are the other factors which may cause in aseptic loosening. Instability and problems related with patella are among the other situations in which revision surgery may be requiredIt is very clear that surgical technique of primary TKR is the main risk factor for early failures [6,7]. Extensive preoperative planning is very important considering aforementioned particulars to achieve accurate prosthetic seating with proper axial alignment. In this chapter, the preoperative planning issues including pre-operative preparations of patient and surgeon will be discussed.
Pre-operative clinical evaluation is very substantial in assessing the current medical status and determining the relative risk profile of the patient. It is very important for the orthopaedic surgeon to understand the basic principles and nuances involved. Preoperative planning initiates with selection of an apropriate candidate for TKR procedure. The patient’s expectations and general risk factors plays an import role in this decision. Questioning of the patient’s complaints and life quality, assesment of the medical condition and detailed physical examination are the essentials of preoperative clinical evaluation.
Total knee replacement was found to be quite effective in terms of improvement in health-related quality of life dimensions, with the occasional exception of the social dimension. The underlying disease is not a life threatening one. The primary indications for total knee arthroplasty are pain and loss of function. Clinical evaluation of the patient has to be initiated by questioning of the complaints and disabilities.
There must be a significant and disabling pain which is resistant to the medical treatment. Spinal disease, ipsilateral hip pathologies, peripheral vascular disease, meniscal pathologies, and bursitis of the knee should be considered in differential diagnosis. The real source of the knee pain must be displayed.
The patient\'s quality of life should be questioned and significant reduction might be taken into consideration It should be remembered that the patients, which are less satisfied following TKR, are the ones with mild pre-operative complaints. All conservative treatment modalities should be exhausted before surgery. The frequent indications for TKR surgery are given on table 1.
Osteoarthritis Inflammatory arthritis Rheumatoid arthritis Osteochondromatosis Villonodular synovitis Metabolic arthritis Osteonecrosis Gout, pseudogout Posttraumatic arthritis Intraarticular fractures Malaligned ankylosis Failed high tibial osteotomies | \n\t\t
The major indications for total knee arthroplasty
Contraindications must be well known and considered before the surgery decision. Absolute contraindications for total knee arthroplasty include knee sepsis, chronic infection, extansor mechanism dysfunction, severe vascular disease, recurvatum deformity secondary to muscular weakness, presence of well functioning knee arthrodesis. There are also relative and contraversial contraindications. These include medical conditions that preclude safe anesthesia, inadequate soft tissue coverage, morbid obesity, neuropathic arthropathy, and history of osteomyelitis around knee joint. A preoperative condition that can adversly affect the patient’s outcome can be considered as a relative contraindication.
A comprehensive medical history and physical examination are the cornerstones of the preoperative assessment. Patient’s medical comorbidities should be optimized preoperatively. Cardiovascular diseases, cerebrovascular diseases, pulmonary diseases, neurologic conditions, rheumatoid arthritis, uropathy, morbid obesity, haematologic and endocrine diseases are the important situations which may affect the intraoperative and postoperative morbidity and mortality.. Drug history of the patient must be questioned too. Sources of infection such as dental, dermatological, urological or respiratory tract infections must be ruled out. Age alone was not found to be an obstacle for an effective surgery, however age related comorbidities should be considered. Additional risks for infection, previous surgeries should be adressed before surgery. Every patient must have a general medical evaluation including laboratory tests, electrocardiogram and chest graphy. The type of the procedure also may enhance the medical risks. For example, simultaneously performed bilateral TKR may be associated with an increased risk of cardiac, respiratory or neurological complications. Low preoperative mental health has also an influence on outcome after TKR [10].
The detailed physical examination should include the range of motion, ligament status, circulation and skin condition evaluation. Furthermore alignment of lower extremities, patellar instability and gait analysis should to be assessed. Additional knowledge and scientific dissemination of surgery outcomes should help to ensure better management of the patients after total knee arthroplasty and to optimize the procedure [12].
Underlying or predisposing orthopaedic diseases, which may interact the outcome of TKR should be reviewed previously. Examples of such common musculoskeletal conditions are as follows: 1) Nerve entrapments affecting motor functions of lower extremity, 2) Adjacent joint degenerative arthritis 3) Presence of any inflamatory arthritis, which may flare after surgery 4) Any musculoskletal disability affecting postoperative mobility 5) Thromboembolic history or predispositions.
An apropriate musculoskeletal radiologic study is essential in planning of TKR. The presence of bone defects might be detected and pre-operative decision whether to use a primary or revision implant should be given. Determination of the joint line is also important in determining the flexion/extension space and balance of the ligaments.
Tracking of the quadriceps mechanism and rotational deformites are other important issues for patellar stability, however may not be assessed on direct radiographs especially in deformed knees with fixed valgus position.
Conventional radiographs are usually adequate for initial radiographic evaluation to confirm the diagnosis or assess the severity of the disease. Preoperative radiographic planning for total knee arthroplasty begins by obtaining a high quality standing antero-posterior (AP) and lateral 52-inch casette graphies. Additional views such as Merchant, tunnel, patella sunrise, orthoroentgenogram or advanced imaging modalities such as CT, MRI may be necessary in extraordinary conditions such as congenital dislocation of the patella, post traumatic deformities, severe deformities, tumors and congenital anomalies.
The AP view should be obtained with the patient in a standing position. The joint space on the weight bearing AP film should be more than 3 mm or within 50% of the joint space of the contralateral knee. Normally, the lateral joint space is wider than the medial space. Articular surfaces of the medial and lateral joint compartments may be best assessed on this view. The presence of associated osteophytes and subcondral bone changes are some of the findings which may be seen on AP graphies.
The lateral aspect of the knee is leaned against the x ray film cassette and flexed 30°. The excessive glide in flexion may be an indicator of posterior cruciate ligament tightness and therefore PCL sacrifiying prosthesis must be considered before the surgery. Patellar height should be assessed on this view using Insall-Salvati ratio. The Insall-Salvati is the ratio of the patellar tendon length (LT) to the length of the patella (LP) (Figure 1). The values above 1,2 is considered as “Patella Alta”, while the values belove 0,8 is considered as “Patella İnfera”. Suprapatellar and posterior regions must be evaluated in terms of detecting the loose bodies.
Patella height is assessed via measuring Insall-Salvati ratio (LP/P) on lateral graphies
Posterior of the knee joint is easily observed on this view and overhanging bone structure or osteophytes should be determined. If left unresected, this overhanging bone can impinge on tibial PE and result with flexion limitation and early wear of the PE.
The lateral view may also allow size selection of the femoral component (Figure 2). Oversizing will create tightness in fexion and increased tension in quadriceps mechanism and undersizing will create looseness in flexion and anterior cortical notching of the femur is also inevitable. Careful preoperative planning with using templates aims to achieve the correct AP dimension for restoring normal kinematics and quadriceps muscle function.
Standing ap view of the lower extremities from hips to ankles is helpful preoperatively for assessing overall alignment (mechanical axis) of the lower extremity. The knee is normally in 7 degree of valgus alignment on AP view.
Proper size of the femoral component is assessed via evaluation of the pre-operative lateral radiographs.
The orthorontgenogram allows the surgeon to determine the varus or valgus alignment of the knees, leg length discrepancy and the presence of extraarticular deformities.
It is essential to ensure to take this radiograph in neutral rotation of the legs to obtain the most accurate measurements. It should be confirmed via inspecting the relationship between the tibia and the fibula, distally and proximally.
Merchant view helps to assess the patellofemoral alignment, trochlear grove and articular surfaces. Preoperatively patellar subluxation seen on this view should alert the surgeon for lateral release of the patella during TKR. Merchant view demonstrates both the patellar and trochlear surfaces. Subluxation can be assessed by measuring the congruence angle (Figure 3). Congruence angle demonstrates the relationship of apex of patella with the trochlear grove’s bisector. Two lines are drawn to measure the congruence angle. First line is the bisector line of femoral sulcus angle and it establishes a zero reference line. Second line is drawn from the apex of the sulcus angle to the lowest point of the patellar articular ridge.
The congruence angle (α) lower than 16° to lateral or medial direction is considered as normal.
If congruence angle is lateral to the reference line this means the angle is positive while angles medial to the reference lines are considered as negative. The angles lower than 16 degree are considered as normal.
Tunnel view shows the posterior aspect of the intercondylar notch and it is useful to evaluate osteocondritis dissecans or intraarticular loose bodies in young patients.
This is called the sunrise view because the patella appears to be rising over the horizon. The sunrise view also helps to identify the patellar malalignment.
Preoperative planning is essential component for surgeon in TKR to obtain desired clinical outcome and radiographic result. Correct implant selection with proper size is one of the important stage in preoperative planning. Patient’s and surgeon’s expectations should be taken into consideration pre-operatively to improve the outcomes and increase the satisfaction after operation [12]. Pre-operative planning of the bone cuts may simplify the surgery. Positioning of the components is very important in acquiring the accurate alignment. Mechanical axis measurement and alignment evaluation on AP and lateral planes may performed on standing X-rays. Also entry points for intramedullary guide pins should be determined for the correct component position.
During the process of planning of TKR, the surgeon aims to obtain the optimal fitting of the implant and the optimal extremity alignment. This is possible for the surgeon by thinking three-dimensionally. The prediction of the surgery pre-operatively should improve the precision of the process and shorten the length of the operation. It should also reduce the complication rate.
Most of the knee replacement systems provide a large number of options for treating conditions that are encountered during surgery. The different systems serve the surgeons different sizes of implants in a wide range. Intra-operative determination of the implant sizes was found more accurate than the pre-operative templating. However pre-operative templating is useful in obtaining proper implant positioning. Working with templates is widely accepted approach, which can help determine component sizes, predict amounts of bony resection, and anticipate surgical steps. Acetate templating was found accurate and reliabile [13]. However, with widespread use of digital radiographs the use of digital templating has recently grown due to advances in reducing errors associated with manipulating films and templates (Figure 4).
Templating
Combining digital templating with picture archiving and communication system PACS brings advantages include saving health care costs, quick and reproducible planning, remote access, and the ability to keep a permanent digital record of the surgical plan.
Templating should also work in preparing the surgeon to some extreme scenarios which may be encountered during surgery. For example; Standart cruciate retaining or sacrifiying implant systems are usually enough to solve the problem in large majority of cases. Constrained or even more complicated sytems with extension stems or wedges may be necessiated in small number of primary cases (Figure 5). Modular systems should be required due to intraoperative complications such as fractures or ligament tears.
Wedge and modular extension stems should be considered in patients which present with a such pre-operative radiograph.
Constrained condylar knee prosthesis (CCK) is commonly used in total knee replacement to overcome the severe ligamentous imbalance problem. CCK may also be preferred if the lateral collateral ligament laxity more than 2 mm persists, even after adequate medial soft tissue release in patients with varus deformity of greater than 20°.
Although women have greater functional limitations than men, at the time of the surgery, they recover faster in early post-operative period. Women also have a greater improvement in WOMAC scores than men after primary surgery. Specific anatomic differences are blamed to be responsible for gender-specific differences after TKR. However, there are conflicting data in the literature regarding these gender-specific outcomes [14].
There are also efforts in reducing costs and improving quality of care, which may planned in preoperative period. Template-directed instrumentation was proposed for simplifying the surgical instruments and saving sterilization costs of unnecessary implant trays as saving measurement. In this novel approach, surgical planning combines digital templating with prepared instruments and components used intraoperatively [15].
Computer based navigation should be prefered in complex cases to overcome the heavily distorded anatomy or malalignment. There are also several quite recent technologies, like patient specific surgical cutting guide systems or robotic assisted implantations in cases of surgeon’s special interest. Beside the medical aspects surgeons have to deal with cost considerations and even discuss with the patient in preoperative planning period [16].
The calculation of enthalpies of formation for the large unsaturated molecules, some of which are not included in the practical range of combustion thermochemistry, based on quantum mechanical first principles which have been possible basing on the recent important advances in computational chemistry. Necessary, Quantum mechanical calculations of molecular thermochemical properties are approximate. Approximations may be employed by the Composite quantum mechanical procedures at each of several computational steps and in the same time it may have an empirical factor to correct the cumulative error. When the error of the various approximations is known within narrow limits, but the question about the accuracy of the “known” value is noticed immediately because the uncertainty of the comparison between the approximate quantum mechanical result and the standard to which it is compared.
The most correct quantum mechanical procedure is been established after its ability to reproduce various accurate experimental results to calculate unknown thermochemical values of explosive compounds or unstable, unsuited to classical thermochemical methods, or to calculate thermochemical properties of radicals, molecules, or ions of fleeting existence [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15]. Here where a major advantage to create the accuracy of inherent hydrogen thermochemical results lies, and it works for encouraging and renewing interest in the diverse literature devoted to hydrogen thermochemistry.
The main part of the quantum chemistry is contended in the total electronic energy of a molecule. And this total electronic energy is a function of the nuclear geometric configuration after Born-Oppenheimer separation of electronic and nuclear motion, therefore generating hyper surfaces of potential energy–for electronically excited states as well as for the ground state.
At the end of this work a very important fact is clear now which clarify that wave function-based quantum-chemical methods can produce molecular electronic energies with an accuracy that surpasses that of experimental measurements of molecular energies (in terms of enthalpies of formation).
An important feature of the wavefunction-based quantum-chemical methodology is the ability to access the exact characterizing of the molecular electronic structure in a systematic manner. To achieve systematic approach two basic steps have been taken, the first step using advanced hierarchy of wavefunction models and the second step using systematic sequence of basis sets – or a nearly complete basis set – of atomic orbitals.
It is noted that the type of wavefunction model used, or density functional, plays an important role in determining accuracy of computed molecular_electronic energies. In addition to the important role played by the flexibility of the one electron basis set of atomic orbitals (AOs) by which the molecular orbitals (MOs) are expanded. It is worth noting that Slater’s determinants are constructed using MOs for use in Kohn - Sham theory or to expand the n-electron wavefunction.
Different ways can be chosen from basis sets of AOs (the literature [16, 17, 18]). As for the approach followed in study of molecular electronic-structure based on wavefunction methods, a well-defined procedure must have been used in order to generating sequences of the basis sets in order to increase flexibility. This way is very useful by generating hierarchies for basis sets, Each next higher level describes an improved systematically of the molecular electronic structure compared to the next lower level. Within the hierarchy the calculated results converge within a prescribed accuracy, and then the basis-set hierarchy ends up effectively complete basis [16]. Therein lies the problem where approaches of wavefunction that depend on the electron-correlation effects of the convergence to an effectively complete basis are very slow. When increasing the number N of AOs in the basis according to an optimal manner, it reduces the basis-set error as
The correlation-consistent basis sets from Dunning and his co-workers [19, 20] represent a popular hierarchy of basis sets. When the valence orbitals are correlated in a calculations only then can the expansion mainly in the Limit extrapolation, until it ends to an effectively complete basis [21, 22, 23, 24, 25, 26]. The term X-tuple zeta basis sets represents to correlation-consistent polarized valence, denoted by cc-pVXZ, and is used in the calculations of this work, where X = D, T, (double, triple zeta). It should be noted that when all the electrons are correlated (core as well as valence orbitals), the cc-pCVXZ basis sets must be used provided 2 ≤ X ≤ 5.
The correlation-consistent basis sets form a basis-set hierarchy well suited for complete basis-set limit extrapolations of the correlation-energy. Then the correlation energy can have been determined depending on X when X → ∞.
In 1977, 27 formulas for two-point linear extrapolation were introduced by Helgaker et al. [27] via the basis sets cc-pCVXZ and cc-pCVYZ, the electron-correlation energies and are computed EX and EY, and the CXY = X3/(X3 Y3) coefficient is determined in Eq. (1),
The EX correlation energy can be recovered in correlation-consistent basis of cc-pVXZ via the Eq. (2), When performing calculations according to the basis sets, cc-pVXZ and cc-pVYZ, two equations with two unknowns are obtained,
Note that through experience [28, 29, 30, 31, 32] that the best estimate of complete basis set limit extrapolation is by using two consecutive basis set when X = Y - 1, for example the pair cc-pCVDZ/cc-pCVTZ, and so on).
The level at which the results were obtained by extrapolation is denoted by cc-pCV(XY)Z, where XY = DT, TQ, and so forth. It is only at this level that the correlation energy is extrapolated.
The CCSD(T)/cc-pV(XY)Z extrapolation will be applied to obtain estimates of the basis-set limit of corrections for M06-2X/6-31g(d) level of theory by calculations of hydrogenation enthalpies of some unsaturated hydrocarbon compounds (Table 1).
Reactions | |
---|---|
Ethyne +2 H2 → ethane | −312.0 ± 0.63 |
Ethene + H2 → ethane | −136.3 ± 0.3 |
Propadiene +2 H2 → propane | −295.1 ± 0.1 |
Prop-1-yne + 2 H2 → propane | −289.6 ± 0.63 |
Prop-1-ene + H2 → propane | −125.0 ± 0.42 |
But-2-yne + 2 H2 → butane | −272.4 ± 1.3 |
Isobutene + H2 → isobutane | −117.8 ± 0.42 |
(2E)-but-2-ene + H2 → butane | −118.5 ± 0.42 |
(2Z)-but-2-ene + H2 → butane | −114.6 ± 0.42 |
(2E)-pent-2-ene + H2 → pentane | −113.8 ± 0.8 |
(2Z)-pent-2-ene + H2 → pentane | −117.7 ± 0.8 |
2-Methylbut-1-ene + H2 → 2-methylbutane | −118.2 ± 0.42 |
2-Methylbut-2-ene + H2 → 2-methylbutane | −111.6 ± 0.3 |
3-Methylbut-1-ene + H2 → 2-methylbutane | −126.3 ± 0.3 |
Cyclopenta-1,3-diene +2 H2 → cyclopentane | −210.8 ± 0.84 |
Hex-1,5-diene +2 H2 → hexane | −251.2 ± 0.42 |
Hex-1-ene + H2 → hexane | −126.0 ± 2.0 |
2,3-Dimethylbuta-1,3-diene +2 H2 → 2,3-dimethylbutane | −223.4 ± 0.63 |
2,3-Dimethylbuta-1-ene + H2 → 2,3-dimethylbutane | −116.1 ± 0.4 |
2,3-Dimethylbuta-2-ene + H2 → 2,3-dimethylbutane | −110.4 ± 0.42 |
3,3-Dimethylbuta-1-ene + H2 → 2,2-dimethylbutane | −125.9 ± 0.63 |
Benzene +3 H2 → cyclohexane | −205.3 ± 0.6 |
Cyclohexa-1,3-diene +2 H2 → cyclohexane | −229.6 ± 0.42 |
Cyclohexene + H2 → cyclohexane | −118.6 ± 0.42 |
Hept-1-ene + H2 → heptane | −125.1 ± 0.3 |
4,4-Dimethylpent-1-ene + H2 → 2,2-dimethylpentane | −122.5 ± 0.42 |
Cyclohepta-1,3,5-triene +3 H2 → cycloheptane | −301.7 ± 1.3 |
Cyclohepta-1,3-diene +2 H2 → cycloheptane | −212.4 ± 0.63 |
Cycloheptene + H2 → cycloheptane | −108.9 ± 0.63 |
Experimental values of hydrogenation enthalpy of some unsaturated hydrocarbons in the gas phase (in kJ Mol−1).
NIST - JANAF thermochemical tables, Ref. [33]
In Section 3, we shall describe the methods used, the molecular equilibrium geometries, and the basis sets. Results will be shown in Section 3.2, including molecular electronic energies, enthalpies of hydrogenation, and statistical analysis of the computational results.
Electronic energies were computed by the density-functional (M06-2X) [34] approach with 6-31g(d) basis set. The M06-2X/6-31g(d) equilibrium geometries of the reactants and products was optimized with the Gaussian 09 program [35]. All CCSD(T)/cc-pV(DT)Z calculations were performed at fixed molecular equilibrium geometries that were optimized at the M06-2X/6-31g(d) level can be found in supporting information.
The total electronic M06-2X/6-31g(d) energies,
Compounds | M06-2X/6-3g(d) | |||
---|---|---|---|---|
H2 | −1.1635655 | 0.013609 | −0.001167 | 0.010304 |
Ethane | −79.771814 | 0.080116 | 0.054255 | 0.075684 |
Ethyne | −77.287772 | 0.031118 | 0.008428 | 0.027383 |
Ethene | −78.536836 | 0.055732 | 0.030890 | 0.051757 |
Propane | −119.064602 | 0.110657 | 0.080306 | 0.105246 |
Propadiene | −116.591917 | 0.060782 | 0.033335 | 0.056103 |
Prop-1-yne | −116.591781 | 0.061355 | 0.033375 | 0.056509 |
Prop-1-ene | −117.834775 | 0.085736 | 0.055653 | 0.080695 |
Cis- butane | −158.357373 | 0.140439 | 0.106229 | 0.133684 |
But-2-yne | −155.894141 | 0.091157 | 0.060488 | 0.085379 |
Isobutene | −158.359492 | 0.139891 | 0.105558 | 0.133229 |
Isobutane | −157.133592 | 0.115796 | 0.083003 | 0.109592 |
Trans-butane | −158.356612 | 0.140562 | 0.106344 | 0.133858 |
(2E)-but-2-ene | −157.132136 | 0.116000 | 0.083013 | 0.109658 |
(2Z)-but-2-ene | −157.130271 | 0.115947 | 0.081911 | 0.109398 |
pentane | −197.650150 | 0.171137 | 0.133095 | 0.163224 |
(2E)-pent-2-ene | −196.424444 | 0.146203 | 0.108344 | 0.138462 |
(2Z)-pent-2-ene | −196.422473 | 0.146538 | 0.108366 | 0.138911 |
2-Methylbutane | −197.650616 | 0.170492 | 0.132540 | 0.162599 |
2-Methylbut-1-ene | −196.425399 | 0.145953 | 0.108348 | 0.138377 |
2-Methylbut-2-ene | −196.428427 | 0.145977 | 0.108516 | 0.138233 |
3-Methylbut-1-ene | −196.421594 | 0.146029 | 0.109827 | 0.138805 |
Cyclopentane | −196.447999 | 0.148834 | 0.115170 | 0.142836 |
Cyclopenta-1,3-diene | −194.004693 | 0.099092 | 0.067447 | 0.094033 |
Hexane | −236.942859 | 0.201129 | 0.159944 | 0.191831 |
Hex-1,2-diene | −234.482131 | 0.151996 | 0.111965 | 0.143762 |
Hex-1-ene | −235.712709 | 0.176575 | 0.135740 | 0.167804 |
2,3-Dimethylbutane | −236.944627 | 0.200377 | 0.160337 | 0.191276 |
2,3-Dimethylbuta-1,3-diene | −234.499027 | 0.152102 | 0.114663 | 0.144198 |
2,3-Dimethylbuta-1-ene | −235.719209 | 0.176092 | 0.136350 | 0.167500 |
2,3-Dimethylbuta-2-ene | −235.721700 | 0.175800 | 0.134436 | 0.166165 |
2,2-Dimethylbutane | −236.946825 | 0.199906 | 0.159467 | 0.190810 |
3,3-Dimethylbuta-1-ene | −235.717309 | 0.175580 | 0.136683 | 0.167108 |
Cyclohexane | −235.752287 | 0.179349 | 0.145101 | 0.172770 |
Benzene | −232.136474 | 0.107012 | 0.076593 | 0.101699 |
Cyclohexa-1,3-diene | −233.301453 | 0.130219 | 0.096574 | 0.124132 |
Cyclohexene | −234.525715 | 0.154825 | 0.119853 | 0.148434 |
Heptane | −276.235598 | 0.231328 | 0.186546 | 0.220693 |
Hept-1-ene | −275.005449 | 0.206749 | 0.162214 | 0.196621 |
2,2-Dimethylpentane | −276.239366 | 0.230120 | 0.186120 | 0.219693 |
4,4-Dimethylpent-1-ene | −275.010862 | 0.205633 | 0.163043 | 0.195795 |
Cycloheptane | −275.035841 | 0.209838 | 0.171462 | 0.201976 |
Cyclohepta-1,3,5-triene | −271.377165 | 0.136474 | 0.100791 | 0.129851 |
Cyclohepta-1,3-diene | −272.592107 | 0.161000 | 0.123047 | 0.153676 |
Cycloheptene | −273.812872 | 0.185183 | 0.147448 | 0.177646 |
Calculated total electronic energy (Eo), Hcorr, Gcorr, and the zero-point vibrational energies (ZPE) at the M06-2X/6-31g(d) level (in hartree).
Compounds | |||
---|---|---|---|
H2 | −1.1723118 | −1.1737775 | −1.17439464 |
Ethane | −79.582513 | −79.674425 | −79.713125 |
Ethyne | −77.109286 | −77.187516 | −77.220455 |
Ethene | −78.354614 | −78.438673 | −78.474067 |
Propane | −118.780810 | −118.914036 | −118.970132 |
Propadiene | −116.314867 | −116.433424 | −116.483343 |
Prop-1-yne | −116.315794 | −116.435339 | −116.485674 |
Prop-1-ene | −117.556774 | −117.682351 | −117.735225 |
Cis- butane | −157.978111 | −158.152797 | −158.226349 |
But-2-yne | −155.521138 | −155.681776 | −155.749412 |
Isobutene | −157.981505 | −158.156035 | −158.229521 |
Isobutane | −156.760003 | −156.927219 | −156.997626 |
Trans -butane | −157.979256 | −158.153758 | −158.227233 |
(2E)-but-2-ene | −156.758622 | −156.925479 | −156.995734 |
(2Z)-but-2-ene | −156.756385 | −156.923701 | −156.994150 |
Pentane | −197.176630 | −197.392504 | −197.483398 |
(2E)-pent-2-ene | −195.956786 | −196.164955 | −196.252605 |
(2Z)-pent-2-ene | −195.954467 | −196.163063 | −196.250893 |
2-Methylbutane | −197.177674 | −197.393756 | −197.484738 |
2-Methylbut-1-ene | −195.957367 | −196.165990 | −196.253832 |
2-Methylbut-2-ene | −195.959195 | −196.167943 | −196.255837 |
3-Methylbut-1-ene | −195.954457 | −196.163021 | −196.250837 |
Cyclopentane | −195.977809 | −196.185015 | −196.272260 |
Cyclopenta-1,3-diene | −193.544249 | −193.735901 | −193.816596 |
Hexane | −236.376059 | −236.633206 | −236.741478 |
1,5-Hexdiene | −233.926959 | −234.168762 | −234.270574 |
Hex-1-ene | −235.151737 | −235.401337 | −235.506432 |
2,3-Dimethylbutane | −236.377394 | −236.635041 | −236.743524 |
2,3-Dimethylbuta-1,3-diene | −233.940431 | −234.183237 | −234.285471 |
2,3-Dimethylbuta-1-ene | −235.156478 | −235.406736 | −235.512108 |
2,3-Dimethylbuta-2-ene | −235.157255 | −235.407711 | −235.513167 |
2,2-Dimethylbutane | −236.380072 | −236.637444 | −236.745811 |
3,3-Dimethylbuta-1-ene | −235.156438 | −235.406113 | −235.511240 |
Cyclohexane | −235.187080 | −235.434840 | −235.539160 |
Benzene | −231.580490 | −231.805751 | −231.900598 |
Cyclohexa-1,3-diene | −232.746205 | −232.978902 | −233.076879 |
Cyclohexene | −233.965459 | −234.205764 | −234.306946 |
Heptane | −275.574466 | −275.872952 | −275.998630 |
Hept-1-ene | −274.350163 | −274.641090 | −274.763585 |
2,2-Dimethylpentane | −275.578608 | −275.877182 | −276.002897 |
4,4-Dimethylpent-1-ene | −274.355543 | −274.646391 | −274.768853 |
Cycloheptane | −274.375461 | −274.664943 | −274.786830 |
Cyclohepta-1,3,5-triene | −270.731145 | −270.997511 | −271.109665 |
Cyclohepta-1,3-diene | −271.941636 | −272.215680 | −272.331066 |
Cycloheptene | −273.157974 | −273.439442 | −273.557955 |
Computed CCSD(T)/ccpVXZ energies at the M06-2X/6-31g(d) geometries, where X = D, T, as well as extrapolated values by the Eq. (2) (in hartree).
M06-2X/cc-pVDZ//M06-2X/6-31g(d) level.
M06-2X/cc-pVTZ//M06-2X/6-31g(d) level.
cc-pV(TD)Z extrapolated level.
Limit energies were obtained using the web page http://sf.anu.edu.au/∼vvv900/cbs/#ref_3 [36].
It is noted from Table 3 that the cc-pV(DT)Z extrapolated level yield electronic energies for all reactants and products less than CCSD(T)/cc-pVDZ and CCSD(T)/cc-pVTZ levels, and it is expected that the calculations of the hydrogenation enthalpies by cc-pV(DT)Z extrapolated level are compatible with the experimental values.
The usual way to calculate enthalpies of reaction is to calculate heats of formation, and take the appropriate sums and difference (Eq. (3)).
However, since Gaussian program provides the sum of electronic and thermal enthalpies, there is a short cut: namely, to simply take the difference of the sums of these values for the reactants and the products. This works since the number of atoms of each element is the same on both sides of the reaction, therefore all the atomic information cancels out, and you need only the molecular data. For example, using the information in Table 2 (or Table 3 for energies), the enthalpy of reaction can be calculated simply by Eq. (4):
CCSD(T)/cc-pVXZ//M06-2X/6–13(d) | ||||
---|---|---|---|---|
Reactions | X = Da | X = Tb | ∆hyd | |
Ethyne +2 H2 → ethane | 16.0 | 4.4 | −0.5 | −312.0 ± 0.63 |
Ethene + H2 → ethane | 5.1 | 2.0 | 0.7 | −136.3 ± 0.3 |
Propadiene +2 H2 → propane | 11.4 | 4.1 | −1.3 | −295.1 ± 0.1 |
Prop-1-yne + 2 H2 → propane | 16.0 | 6.1 | −0.5 | −289.6 ± 0.63 |
Prop-1-ene + H2 → propane | 4.9 | 2.0 | −0.4 | −125.0 ± 0.42 |
But-2-yne + 2 H2 → butane | 15.2 | 4.1 | −0.6 | −272.4 ± 1.3 |
Isobutene + H2 isobutane | 7.6 | 3.0 | 1.1 | −117.8 ± 0.42 |
(2E)-but-2-ene + H2 → butane | 6.1 | 1.7 | −0.2 | −118.5 ± 0.42 |
(2Z)-but-2-ene + H2 → butane | 7.6 | 3.9 | 2.4 | −114.6 ± 0.42 |
(2E)-pent-2-ene + H2 → pentane | 5.8 | 2.3 | 0.8 | −113.8 ± 0.8 |
(2Z)-pent-2-ene + H2 → pentane | −1.7 | −5.3 | −6.7 | −117.7 ± 0.8 |
2-Methylbut-1-ene + H2 → 2-methylbutane | 2.9 | −1.3 | −3.1 | −118.2 ± 0.42 |
2-Methylbut-2-ene + H2 → 2-methylbutane | 4.7 | 0.2 | −1.7 | −111.6 ± 0.3 |
3-Methylbut-1-ene + H2 → 2-methylbutane | 2.6 | −1.4 | −3.1 | −126.3 ± 0.3 |
Cyclopenta-1,3-diene +2 H2 → cyclopentane | 11.1 | 4.4 | 1.6 | −210.8 ± 0.84 |
Hex-1,5-diene +2 H2 → hexane | 13.1 | 5.8 | 2.8 | −251.2 ± 0.42 |
Hex-1-ene + H2 → hexane | 5.6 | 1.6 | 0.0 | −126.0 ± 2.0 |
2,3-Dimethylbuta-1,3-diene +2 H2 → 2,3-dimethylbutane | 11.3 | 2.7 | −0.9 | −223.4 ± 0.63 |
2,3-Dimethylbuta-1-ene + H2 → 2,3-dimethylbutane | 7.2 | 2.9 | 1.0 | −116.1 ± 0.4 |
2,3-Dimethylbuta-2-ene + H2 → 2,3-dimethylbutane | 10.1 | 2.7 | −0.9 | −110.4 ± 0.42 |
3,3-Dimethylbuta-1-ene + H2 → 2,2-dimethylbutane | 4.5 | 0.9 | −0.6 | −125.9 ± 0.63 |
Benzene +3 H2 → cyclohexane | 18.6 | 6.4 | 1.3 | −205.3 ± 0.6 |
Cyclohexa-1,3-diene +2 H2 → cyclohexane | 13.1 | 5.1 | 1.8 | −229.6 ± 0.42 |
Cyclohexene + H2 → cyclohexane | 6.0 | 1.8 | 0.0 | −118.6 ± 0.42 |
Hept-1-ene + H2 → heptane | 6.4 | 2.4 | 0.8 | −125.1 ± 0.3 |
4,4-Dimethylpent-1-ene + H2 → 2,2-dimethylpentane | 5.9 | 2.5 | 1.0 | −122.5 ± 0.42 |
Cyclohepta-1,3,5-triene +3 H2 → cycloheptane | 18.6 | 8.0 | 3.5 | −301.7 ± 1.3 |
Cyclohepta-1,3-diene +2 H2 → cycloheptane | 12.5 | 5.6 | 2.6 | −212.4 ± 0.63 |
Cycloheptene + H2 → cycloheptane | 4.5 | 1.7 | 0.6 | −108.9 ± 0.63 |
Difference between experimental and calculation values of standard enthalpies of hydrogenation of some unsaturated hydrocarbons in the gas phase at 298.15 K (in kJ Mol−1).
CCSD(T)/cc-pVDZ//M06-2X/6-31g(d) level.
CCSD(T)/cc-pVTZ//M06-2X/6-31g(d) level.
cc-pV(TD)Z extrapolated level.
NIST-JANAF thermo-chemical tables.
Level | MAD | RMS | Error% | SD | R2 |
---|---|---|---|---|---|
CCSD(T)/cc-pVDZ//M06-2X/6-31g(d) | 8.8 | 10.0 | 5.0% | 2.78 | 0.9987 |
CCSD(T)//cc-pVTZ//M06-2X/6-31g(d) | 3.4 | 3.9 | 2.0% | 2.11 | 0.9992 |
cc-pV(DT)Z extrapolated level | 1.5 | 2.1 | 1.0% | 2.12 | 0.9992 |
Statistical parameters for all used methods to calculate hydrogenation enthalpies. (in kJ Mol–1).
Calculated versus experimental hydrogenation enthalpy
Our best theoretical estimates of the enthalpies of hydrogenation are based on basis set limit extrapolation calculations, when the pair cc-pVDZ and cc-pVTZ are used, and the mean absolute deviation (MAD) between experimental and calculated values is 1.5 kJ mol−1 (Table 5). The enthalpies of hydrogenation of some alkenes (12 compounds) have been calculated at the HF, B3LYP, M06, MP2, G3, G4, CBS-QB3, CBS-APNO, and W1BD levels and, in the case of the first four methods, using a variety of basis sets up to aug-ccpVTZ [37], and it is found that the MAD decreases gradually from the first to the last method (18.4–4.2 kJ mol−1). Moreover, Rogers et al. [38, 39, 40] calculated the hydrogenation enthalpy at 298.15 K for reactions involving cyclic and acyclic C4 (20 reactions), cyclic C5 (23 reactions) and C6 (24 reactions) hydrocarbons using the G2 and G2(MP2) ab initio methods, and it is found that the MAD is about 3.3, 3.7 and 5.0 kJ −1, respectively.
Enthalpies of hydrogenation are relatively easy to calculate with CCSD(T)/cc-pVXZ/M06-31g(d)/6-31g(d) level, where X = D, T, giving fairly good agreement with experiment, especially when cc-pVTZ basis set are used, and basis set extrapolation techniques by Eq. (2) seem to represent an easy-to-use alternative, especially when the pair cc-pVDZ and cc-pVTZ are used.
These Terms and Conditions outline the rules and regulations pertaining to the use of IntechOpen’s website www.intechopen.com and all the subdomains owned by IntechOpen located at 5 Princes Gate Court, London, SW7 2QJ, United Kingdom.
',metaTitle:"Terms and Conditions",metaDescription:"These terms and conditions outline the rules and regulations for the use of IntechOpen Website at https://intechopen.com and all its subdomains owned by Intech Limited located at 7th floor, 10 Lower Thames Street, London, EC3R 6AF, UK.",metaKeywords:null,canonicalURL:"/page/terms-and-conditions",contentRaw:'[{"type":"htmlEditorComponent","content":"By accessing the website at www.intechopen.com you are agreeing to be bound by these Terms of Service, all applicable laws and regulations, and agree that you are responsible for compliance with any applicable local laws. Use and/or access to this site is based on full agreement and compliance of these Terms. All materials contained on this website are protected by applicable copyright and trademark laws.
\\n\\nThe following terminology applies to these Terms and Conditions, Privacy Statement, Disclaimer Notice, and any or all Agreements:
\\n\\n“Client”, “Customer”, “You” and “Your” refers to you, the person accessing this website and accepting the Company’s Terms and Conditions;
\\n\\n“The Company”, “Ourselves”, “We”, “Our” and “Us”, refers to our Company, IntechOpen;
\\n\\n“Party”, “Parties”, or “Us”, refers to both the Client and ourselves, or either the Client or ourselves.
\\n\\nAll Terms refer to the offer, acceptance, and consideration of payment necessary to provide assistance to the Client in the most appropriate manner, whether by formal meetings of a fixed duration, or by any other agreed means, for the express purpose of meeting the Client’s needs in respect of provision of the Company’s stated services/products, and in accordance with, and subject to, the prevailing laws of the United Kingdom.
\\n\\nAny use of the above terminology, or other words in the singular, plural, capitalization and/or he/she or they, are taken as interchangeable.
\\n\\nUnless otherwise stated, IntechOpen and/or its licensors own the intellectual property rights for all materials on www.intechopen.com. All intellectual property rights are reserved. You may view, download, share, link and print pages from www.intechopen.com for your own personal use, subject to the restrictions set out in these Terms and Conditions.
\\n\\nWe employ the use of cookies. By using the IntechOpen website you consent to the use of cookies in accordance with IntechOpen’s Privacy Policy. Most modern day interactive websites use cookies to enable the retrieval of user details for each visit. On our site, cookies are predominantly used to enable functionality and ease of use for those visiting the site.
\\n\\nIn no circumstances shall IntechOpen or its suppliers be liable for any damages (including, without limitation, damages for loss of data or profit, or due to business interruption) arising out of the use, or inability to use, the materials on IntechOpen's websites, even if IntechOpen or an IntechOpen authorized representative has been notified orally or in writing of the possibility of such damage. Some jurisdictions do not allow limitations on implied warranties, or limitations of liability for consequential or incidental damages; consequently, these limitations may not apply to you.
\\n\\nIntechopen.com website content and services are provided on an "AS IS" and an "AS AVAILABLE" basis. Material appearing on www.intechopen.com could include minor technical, typographical, or photographic errors. IntechOpen may make changes to any material contained on its website at any time without notice.
\\n\\nIntechOpen has no formal affiliation to any external sites that link to www.intechopen.com, unless otherwise specifically stated. As such, it is not responsible for content that appears on any such sites. The inclusion of any link to IntechOpen does not imply endorsement by IntechOpen. Use of any such linked website is done solely at the user's own discretion.
\\n\\nWe reserve the right of ownership over our entire website www.intechopen.com, and all contents. By using our services, you agree to remove all links to our website immediately upon request. We also reserve the right to amend these Terms and Conditions and our linking policy at any time. By continuing to link to our website, you agree to be bound to, and abide by, these linking Terms and Conditions.
\\n\\nIf you find any link on our website, or any linked website, objectionable for any reason, please Contact Us. We will consider all requests to remove links but will have no obligation to do so.
\\n\\nWithout prior approval and express written permission, you may not create frames around our web pages or use other techniques that alter in any way the visual presentation or appearance of our website.
\\n\\nIntechOpen may revise its Terms of Service for its website at any time without notice. By using this website, you are agreeing to be bound by the current version of all Terms at the time of use.
\\n\\nThese Terms and Conditions are governed by and construed in accordance with the laws of the United Kingdom and you irrevocably submit to the exclusive jurisdiction of the courts in London, United Kingdom.
\\n\\nCroatian version of Terms and Conditions available here
\\n"}]'},components:[{type:"htmlEditorComponent",content:'By accessing the website at www.intechopen.com you are agreeing to be bound by these Terms of Service, all applicable laws and regulations, and agree that you are responsible for compliance with any applicable local laws. Use and/or access to this site is based on full agreement and compliance of these Terms. All materials contained on this website are protected by applicable copyright and trademark laws.
\n\nThe following terminology applies to these Terms and Conditions, Privacy Statement, Disclaimer Notice, and any or all Agreements:
\n\n“Client”, “Customer”, “You” and “Your” refers to you, the person accessing this website and accepting the Company’s Terms and Conditions;
\n\n“The Company”, “Ourselves”, “We”, “Our” and “Us”, refers to our Company, IntechOpen;
\n\n“Party”, “Parties”, or “Us”, refers to both the Client and ourselves, or either the Client or ourselves.
\n\nAll Terms refer to the offer, acceptance, and consideration of payment necessary to provide assistance to the Client in the most appropriate manner, whether by formal meetings of a fixed duration, or by any other agreed means, for the express purpose of meeting the Client’s needs in respect of provision of the Company’s stated services/products, and in accordance with, and subject to, the prevailing laws of the United Kingdom.
\n\nAny use of the above terminology, or other words in the singular, plural, capitalization and/or he/she or they, are taken as interchangeable.
\n\nUnless otherwise stated, IntechOpen and/or its licensors own the intellectual property rights for all materials on www.intechopen.com. All intellectual property rights are reserved. You may view, download, share, link and print pages from www.intechopen.com for your own personal use, subject to the restrictions set out in these Terms and Conditions.
\n\nWe employ the use of cookies. By using the IntechOpen website you consent to the use of cookies in accordance with IntechOpen’s Privacy Policy. Most modern day interactive websites use cookies to enable the retrieval of user details for each visit. On our site, cookies are predominantly used to enable functionality and ease of use for those visiting the site.
\n\nIn no circumstances shall IntechOpen or its suppliers be liable for any damages (including, without limitation, damages for loss of data or profit, or due to business interruption) arising out of the use, or inability to use, the materials on IntechOpen's websites, even if IntechOpen or an IntechOpen authorized representative has been notified orally or in writing of the possibility of such damage. Some jurisdictions do not allow limitations on implied warranties, or limitations of liability for consequential or incidental damages; consequently, these limitations may not apply to you.
\n\nIntechopen.com website content and services are provided on an "AS IS" and an "AS AVAILABLE" basis. Material appearing on www.intechopen.com could include minor technical, typographical, or photographic errors. IntechOpen may make changes to any material contained on its website at any time without notice.
\n\nIntechOpen has no formal affiliation to any external sites that link to www.intechopen.com, unless otherwise specifically stated. As such, it is not responsible for content that appears on any such sites. The inclusion of any link to IntechOpen does not imply endorsement by IntechOpen. Use of any such linked website is done solely at the user's own discretion.
\n\nWe reserve the right of ownership over our entire website www.intechopen.com, and all contents. By using our services, you agree to remove all links to our website immediately upon request. We also reserve the right to amend these Terms and Conditions and our linking policy at any time. By continuing to link to our website, you agree to be bound to, and abide by, these linking Terms and Conditions.
\n\nIf you find any link on our website, or any linked website, objectionable for any reason, please Contact Us. We will consider all requests to remove links but will have no obligation to do so.
\n\nWithout prior approval and express written permission, you may not create frames around our web pages or use other techniques that alter in any way the visual presentation or appearance of our website.
\n\nIntechOpen may revise its Terms of Service for its website at any time without notice. By using this website, you are agreeing to be bound by the current version of all Terms at the time of use.
\n\nThese Terms and Conditions are governed by and construed in accordance with the laws of the United Kingdom and you irrevocably submit to the exclusive jurisdiction of the courts in London, United Kingdom.
\n\nCroatian version of Terms and Conditions available here
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. In the Engineering side, Digital Signal Processing, Computer Architecture, Electronics Devices, Digital Filtering and Engineering Management.\nApart from his Academic Interest and activities he loves sport especially, Cricket, Football, Snooker and Squash. He plays cricket for Esbjerg city in the second division team as an opener wicket keeper batsman. He is a very good player of squash but has not played squash since his arrival in Denmark.",institutionString:null,institution:null},{id:"611",title:"Prof.",name:"T",middleName:null,surname:"Nagarajan",slug:"t-nagarajan",fullName:"T Nagarajan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universiti Teknologi Petronas",country:{name:"Malaysia"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:6675},{group:"region",caption:"Middle and South America",value:2,count:5955},{group:"region",caption:"Africa",value:3,count:2459},{group:"region",caption:"Asia",value:4,count:12718},{group:"region",caption:"Australia and Oceania",value:5,count:1017},{group:"region",caption:"Europe",value:6,count:17720}],offset:12,limit:12,total:134177},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{topicId:"21"},books:[{type:"book",id:"11434",title:"Indigenous Populations - Perspectives From Scholars and Practitioners in Contemporary Times",subtitle:null,isOpenForSubmission:!0,hash:"c0d1c1c93a36fd9d726445966316a373",slug:null,bookSignature:"Dr. Sylvanus Gbendazhi Barnabas",coverURL:"https://cdn.intechopen.com/books/images_new/11434.jpg",editedByType:null,editors:[{id:"293764",title:"Dr.",name:"Sylvanus",surname:"Barnabas",slug:"sylvanus-barnabas",fullName:"Sylvanus Barnabas"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11436",title:"Beauty - Evolutionary, Social and Cultural Perspectives on Attractiveness",subtitle:null,isOpenForSubmission:!0,hash:"8f2773e5d4ffe767f38dd15712258e8c",slug:null,bookSignature:"Dr. Farid Pazhoohi",coverURL:"https://cdn.intechopen.com/books/images_new/11436.jpg",editedByType:null,editors:[{id:"470837",title:"Dr.",name:"Farid",surname:"Pazhoohi",slug:"farid-pazhoohi",fullName:"Farid Pazhoohi"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11443",title:"Empathy - Advanced Research and Applications",subtitle:null,isOpenForSubmission:!0,hash:"4c1042dfe15aa9cea6019524c4cbff38",slug:null,bookSignature:"Ph.D. Sara Ventura",coverURL:"https://cdn.intechopen.com/books/images_new/11443.jpg",editedByType:null,editors:[{id:"227763",title:"Ph.D.",name:"Sara",surname:"Ventura",slug:"sara-ventura",fullName:"Sara Ventura"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11444",title:"Happiness - Biopsychosocial and Anthropological Perspectives",subtitle:null,isOpenForSubmission:!0,hash:"fa84e7fc3611e5428e070239dcf5a93f",slug:null,bookSignature:"Dr. Floriana Irtelli and Prof. Fabio Gabrielli",coverURL:"https://cdn.intechopen.com/books/images_new/11444.jpg",editedByType:null,editors:[{id:"174641",title:"Dr.",name:"Floriana",surname:"Irtelli",slug:"floriana-irtelli",fullName:"Floriana Irtelli"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11478",title:"Recent Advances in the Study of Dyslexia",subtitle:null,isOpenForSubmission:!0,hash:"26764a18c6b776698823e0e1c3022d2f",slug:null,bookSignature:"Prof. Jonathan Glazzard",coverURL:"https://cdn.intechopen.com/books/images_new/11478.jpg",editedByType:null,editors:[{id:"294281",title:"Prof.",name:"Jonathan",surname:"Glazzard",slug:"jonathan-glazzard",fullName:"Jonathan Glazzard"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11777",title:"LGBT Communities",subtitle:null,isOpenForSubmission:!0,hash:"e08bb222c250dcebf093b7ab595a14a7",slug:null,bookSignature:"Dr. Deborah Woodman",coverURL:"https://cdn.intechopen.com/books/images_new/11777.jpg",editedByType:null,editors:[{id:"463750",title:"Dr.",name:"Deborah",surname:"Woodman",slug:"deborah-woodman",fullName:"Deborah Woodman"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11781",title:"Family Therapy - Recent Advances in Clinical and Crisis Settings",subtitle:null,isOpenForSubmission:!0,hash:"8c5b7d5e4233594de70d2f830209b757",slug:null,bookSignature:"Dr. Oluwatoyin Olatundun Ilesanmi",coverURL:"https://cdn.intechopen.com/books/images_new/11781.jpg",editedByType:null,editors:[{id:"440049",title:"Dr.",name:"Oluwatoyin Olatundun",surname:"Ilesanmi",slug:"oluwatoyin-olatundun-ilesanmi",fullName:"Oluwatoyin Olatundun Ilesanmi"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11782",title:"Personality Traits - The Role in Psychopathology",subtitle:null,isOpenForSubmission:!0,hash:"d3a491e5194cad4c59b900dd57a11842",slug:null,bookSignature:" Vladimir V. Kalinin",coverURL:"https://cdn.intechopen.com/books/images_new/11782.jpg",editedByType:null,editors:[{id:"31572",title:null,name:"Vladimir V.",surname:"Kalinin",slug:"vladimir-v.-kalinin",fullName:"Vladimir V. Kalinin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11783",title:"Motivation and Success",subtitle:null,isOpenForSubmission:!0,hash:"f660b7cd35b9af94bdfc3564df138161",slug:null,bookSignature:"Dr. Simon George Taukeni",coverURL:"https://cdn.intechopen.com/books/images_new/11783.jpg",editedByType:null,editors:[{id:"202046",title:"Dr.",name:"Simon George",surname:"Taukeni",slug:"simon-george-taukeni",fullName:"Simon George Taukeni"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12109",title:"Identifying Occupational Stress and Coping Strategies",subtitle:null,isOpenForSubmission:!0,hash:"09a2f5fe50b90b20637b7aceccf1cfdd",slug:null,bookSignature:"Dr. Kavitha Palaniappan",coverURL:"https://cdn.intechopen.com/books/images_new/12109.jpg",editedByType:null,editors:[{id:"311189",title:"Dr.",name:"Kavitha",surname:"Palaniappan",slug:"kavitha-palaniappan",fullName:"Kavitha Palaniappan"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12127",title:"The Psychology of Sports",subtitle:null,isOpenForSubmission:!0,hash:"4bf52abfe589a320744c40ca5fe41a89",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12127.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12135",title:"Parenting",subtitle:null,isOpenForSubmission:!0,hash:"5fcfe3872ea161c9c879e0667a220ca8",slug:null,bookSignature:"",coverURL:"//cdnintech.com/web/frontend/www/assets/cover.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:38},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:13},{group:"topic",caption:"Business, Management and Economics",value:7,count:7},{group:"topic",caption:"Chemistry",value:8,count:23},{group:"topic",caption:"Computer and Information Science",value:9,count:24},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:15},{group:"topic",caption:"Engineering",value:11,count:65},{group:"topic",caption:"Environmental Sciences",value:12,count:10},{group:"topic",caption:"Immunology and Microbiology",value:13,count:16},{group:"topic",caption:"Materials Science",value:14,count:25},{group:"topic",caption:"Mathematics",value:15,count:11},{group:"topic",caption:"Medicine",value:16,count:116},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:6},{group:"topic",caption:"Neuroscience",value:18,count:4},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:9},{group:"topic",caption:"Physics",value:20,count:9},{group:"topic",caption:"Psychology",value:21,count:10},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:9},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:4}],offset:12,limit:12,total:14},popularBooks:{featuredBooks:[{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10195",title:"Serotonin and the CNS",subtitle:"New Developments in Pharmacology and Therapeutics",isOpenForSubmission:!1,hash:"7ed9d96da98233a885bd2869a8056c36",slug:"serotonin-and-the-cns-new-developments-in-pharmacology-and-therapeutics",bookSignature:"Berend Olivier",coverURL:"https://cdn.intechopen.com/books/images_new/10195.jpg",editors:[{id:"71579",title:"Prof.",name:"Berend",middleName:null,surname:"Olivier",slug:"berend-olivier",fullName:"Berend Olivier"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11012",title:"Radiopharmaceuticals",subtitle:"Current Research for Better Diagnosis and Therapy",isOpenForSubmission:!1,hash:"f9046d6f96148b285e776f384991120d",slug:"radiopharmaceuticals-current-research-for-better-diagnosis-and-therapy",bookSignature:"Farid A. Badria",coverURL:"https://cdn.intechopen.com/books/images_new/11012.jpg",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9974",title:"E-Learning and Digital Education in the Twenty-First Century",subtitle:null,isOpenForSubmission:!1,hash:"88b58d66e975df20425fc1dfd22d53aa",slug:"e-learning-and-digital-education-in-the-twenty-first-century",bookSignature:"M. Mahruf C. Shohel",coverURL:"https://cdn.intechopen.com/books/images_new/9974.jpg",editors:[{id:"94099",title:"Dr.",name:"M. Mahruf C.",middleName:null,surname:"Shohel",slug:"m.-mahruf-c.-shohel",fullName:"M. Mahruf C. Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4431},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1677,editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10195",title:"Serotonin and the CNS",subtitle:"New Developments in Pharmacology and Therapeutics",isOpenForSubmission:!1,hash:"7ed9d96da98233a885bd2869a8056c36",slug:"serotonin-and-the-cns-new-developments-in-pharmacology-and-therapeutics",bookSignature:"Berend Olivier",coverURL:"https://cdn.intechopen.com/books/images_new/10195.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1337,editors:[{id:"71579",title:"Prof.",name:"Berend",middleName:null,surname:"Olivier",slug:"berend-olivier",fullName:"Berend Olivier"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1309,editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:847,editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",publishedDate:"June 15th 2022",numberOfDownloads:2273,editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:591,editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:515,editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:413,editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",publishedDate:"June 8th 2022",numberOfDownloads:2194,editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:341,editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"11043",title:"Endometriosis",subtitle:"Recent Advances, New Perspectives and Treatments",isOpenForSubmission:!1,hash:"7baf1c70b11d41400bb9302ae9411ca4",slug:"endometriosis-recent-advances-new-perspectives-and-treatments",bookSignature:"Giovana Ap. Gonçalves",coverURL:"https://cdn.intechopen.com/books/images_new/11043.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"185930",title:"Associate Prof.",name:"Giovana",middleName:null,surname:"Gonçalves",slug:"giovana-goncalves",fullName:"Giovana Gonçalves"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10536",title:"Campylobacter",subtitle:null,isOpenForSubmission:!1,hash:"c4b132b741dd0a2ed539b824ab63965f",slug:"campylobacter",bookSignature:"Guillermo Tellez-Isaias and Saeed El-Ashram",coverURL:"https://cdn.intechopen.com/books/images_new/10536.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"73465",title:"Dr.",name:"Guillermo",middleName:null,surname:"Téllez",slug:"guillermo-tellez",fullName:"Guillermo Téllez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10798",title:"Starch",subtitle:"Evolution and Recent Advances",isOpenForSubmission:!1,hash:"f197f6062c1574a9a90e50a369271bcf",slug:"starch-evolution-and-recent-advances",bookSignature:"Martins Ochubiojo Emeje",coverURL:"https://cdn.intechopen.com/books/images_new/10798.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11083",title:"Hazardous Waste Management",subtitle:null,isOpenForSubmission:!1,hash:"d553bd4f6f1c4b115ca69bd19faac7dc",slug:"hazardous-waste-management",bookSignature:"Rajesh Banu Jeyakumar, Kavitha Sankarapandian and Yukesh Kannah Ravi",coverURL:"https://cdn.intechopen.com/books/images_new/11083.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"218539",title:"Dr.",name:"Rajesh Banu",middleName:null,surname:"Jeyakumar",slug:"rajesh-banu-jeyakumar",fullName:"Rajesh Banu Jeyakumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10848",title:"Tribology of Machine Elements",subtitle:"Fundamentals and Applications",isOpenForSubmission:!1,hash:"3c4ca4c4692ca8d4fa749b4ae81ec1fa",slug:"tribology-of-machine-elements-fundamentals-and-applications",bookSignature:"Giuseppe Pintaude, Tiago Cousseau and Anna Rudawska",coverURL:"https://cdn.intechopen.com/books/images_new/10848.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"18347",title:"Prof.",name:"Giuseppe",middleName:null,surname:"Pintaude",slug:"giuseppe-pintaude",fullName:"Giuseppe Pintaude"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10856",title:"Crude Oil",subtitle:"New Technologies and Recent Approaches",isOpenForSubmission:!1,hash:"8d0a7ca35b3de95b295dc4eab39a087e",slug:"crude-oil-new-technologies-and-recent-approaches",bookSignature:"Manar Elsayed Abdel-Raouf and Mohamed Hasan El-Keshawy",coverURL:"https://cdn.intechopen.com/books/images_new/10856.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"102626",title:"Prof.",name:"Manar",middleName:null,surname:"Elsayed Abdel-Raouf",slug:"manar-elsayed-abdel-raouf",fullName:"Manar Elsayed Abdel-Raouf"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9625",title:"Spinocerebellar Ataxia",subtitle:"Concepts, Particularities and Generalities",isOpenForSubmission:!1,hash:"365a7025fd46eb45de2549bdd9d50b98",slug:"spinocerebellar-ataxia-concepts-particularities-and-generalities",bookSignature:"Patricia Bozzetto Ambrosi",coverURL:"https://cdn.intechopen.com/books/images_new/9625.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"221787",title:"Dr.",name:"Patricia",middleName:null,surname:"Bozzetto Ambrosi",slug:"patricia-bozzetto-ambrosi",fullName:"Patricia Bozzetto Ambrosi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10905",title:"Plant Defense Mechanisms",subtitle:null,isOpenForSubmission:!1,hash:"84ad5b27dde5f01dc76087d0fd6fa834",slug:"plant-defense-mechanisms",bookSignature:"Josphert Ngui Kimatu",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"224171",title:"Prof.",name:"Josphert N.",middleName:null,surname:"Kimatu",slug:"josphert-n.-kimatu",fullName:"Josphert N. Kimatu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10686",title:"Natural Gas",subtitle:"New Perspectives and Future Developments",isOpenForSubmission:!1,hash:"581763788a6a59e653a9d1d9b5a42d79",slug:"natural-gas-new-perspectives-and-future-developments",bookSignature:"Maryam Takht Ravanchi",coverURL:"https://cdn.intechopen.com/books/images_new/10686.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"2416",title:"Dr.",name:"Maryam",middleName:null,surname:"Takht Ravanchi",slug:"maryam-takht-ravanchi",fullName:"Maryam Takht Ravanchi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10988",title:"Railway Transport Planning and Manageme",subtitle:null,isOpenForSubmission:!1,hash:"5cb54cc53caedad9ec78372563c82e2c",slug:"railway-transport-planning-and-management",bookSignature:"Stefano de Luca, Roberta Di Pace and Chiara Fiori",coverURL:"https://cdn.intechopen.com/books/images_new/10988.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"271061",title:"Prof.",name:"Stefano",middleName:null,surname:"de Luca",slug:"stefano-de-luca",fullName:"Stefano de Luca"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"743",title:"Engineering Dynamics",slug:"electrical-and-electronic-engineering-engineering-dynamics",parent:{id:"116",title:"Electrical and Electronic Engineering",slug:"electrical-and-electronic-engineering"},numberOfBooks:1,numberOfSeries:0,numberOfAuthorsAndEditors:11,numberOfWosCitations:27,numberOfCrossrefCitations:8,numberOfDimensionsCitations:9,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"743",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"6017",title:"Switched Reluctance Motor",subtitle:"Concept, Control and Applications",isOpenForSubmission:!1,hash:"ea21009431eeed49e94d3a693d47f09d",slug:"switched-reluctance-motor-concept-control-and-applications",bookSignature:"Ahmed Tahour and Abdel Ghani Aissaoui",coverURL:"https://cdn.intechopen.com/books/images_new/6017.jpg",editedByType:"Edited by",editors:[{id:"26712",title:"Dr.",name:"Ahmed",middleName:null,surname:"Tahour",slug:"ahmed-tahour",fullName:"Ahmed Tahour"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:1,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"55670",doi:"10.5772/intechopen.69149",title:"Switched Reluctance Motor Topologies: A Comprehensive Review",slug:"switched-reluctance-motor-topologies-a-comprehensive-review",totalDownloads:4958,totalCrossrefCites:4,totalDimensionsCites:5,abstract:"Switched reluctance motor (SRM) is gaining much interest in industrial applications such as wind energy systems and electric vehicles due to its simple and rugged construction, high‐speed operation ability, insensitivity to high temperature, and its features of fault tolerance. With continued research, different topologies have emerged presenting less torque ripple, high efficiency, high power factor, and high power density. However, there has always been a trade‐off between gaining some of the advantageous and losing some with each new technology. In this chapter, various SRM topologies, design, principle of operation, and respective phase switching schemes are extensively reviewed, and their advantages and drawbacks are discussed. On the other hand, some of SRM limitations (such as excitation penalty, control complexity, noise, and vibration) have prompted research into the incorporation of permanent magnets into the basic SRM structure, and therefore, the chapter also includes discussion on a new class of SRM with permanent magnet assist (PM‐assist) called doubly salient permanent magnet (DSPMM). The DSPM motor incorporates the merits of both the PM brushless motor and the SRM.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Mohammad Mahdi Bouiabady, Aliakbar Damaki Aliabad and\nEbrahim Amiri",authors:[{id:"175468",title:"Dr.",name:"Ebrahim",middleName:null,surname:"Amiri",slug:"ebrahim-amiri",fullName:"Ebrahim Amiri"},{id:"203202",title:"Mr.",name:"Mohammad Mahdi",middleName:null,surname:"Bouiabady",slug:"mohammad-mahdi-bouiabady",fullName:"Mohammad Mahdi Bouiabady"},{id:"203203",title:"Dr.",name:"Aliakbar",middleName:null,surname:"Damaki Aliabad",slug:"aliakbar-damaki-aliabad",fullName:"Aliakbar Damaki Aliabad"}]},{id:"55383",doi:"10.5772/intechopen.68911",title:"Switched Reluctance Motor Drives for Hybrid Electric Vehicles",slug:"switched-reluctance-motor-drives-for-hybrid-electric-vehicles",totalDownloads:3344,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"Because of the ever‐increasing concerns on the energy utilization and environmental protection, the development of hybrid electric vehicles (HEVs) has become a hot research topic. As the major part of HEV technologies, the electric motor drives have to offer high efficiency, high power density, high controllability, wide‐speed operating range, and maintenance‐free operation. In particular, the switched reluctance (SR) motor drive can achieve most of these goals; therefore, this motor type has drawn much attention in the past. This chapter aims to serve as an overview of the latest developments of the SR motor drive, purposely for HEV applications. To be specific, the discussions on motor structures for torque density enhancement and torque ripple minimization are covered.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Christopher H.T. Lee, James L. Kirtley, Jr. and M. Angle",authors:[{id:"201412",title:"Dr.",name:"Christopher H. T.",middleName:null,surname:"Lee",slug:"christopher-h.-t.-lee",fullName:"Christopher H. T. Lee"}]},{id:"55535",doi:"10.5772/intechopen.69228",title:"Four‐Quadrant Control of Switched Reluctance Machine",slug:"four-quadrant-control-of-switched-reluctance-machine",totalDownloads:1639,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"This chapter illustrates modeling techniques and software simulation of the switched reluctance machine (SRM) machine models with controllers for efficient operation. The first model is based on torque and flux data generated through finite element analysis (FEA) and the second model is geometry-based machine model, which are used to develop the operation logic for four-quadrant control of an SRM. The results obtained from these models were used to develop a control strategy to adapt turn-on and turn-off (commutation) angles efficiently. Two digital controllers, namely the phase current controller for regulating current with a hysteresis band and the PI (proportional-integral) speed controller for regulating the speed, are developed to deliver the desired output torque. The controller is based on a negative feedback closed-loop control system.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Sandeep Narla",authors:[{id:"201434",title:"M.Sc.",name:"Sandeep",middleName:null,surname:"Narla",slug:"sandeep-narla",fullName:"Sandeep Narla"}]},{id:"55678",doi:"10.5772/intechopen.69280",title:"Direct Instantaneous Torque Controlled Switched Reluctance Motor Drive for Fan Type Load and Constant Torque Load",slug:"direct-instantaneous-torque-controlled-switched-reluctance-motor-drive-for-fan-type-load-and-constan",totalDownloads:1544,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Switched reluctance motor (SRM) drives can be a good competitor to conventional induction and permanent magnet motors in variable speed applications because of advantages, such as simple construction, no rotor windings, high torque to inertia ratio, adaptability to hostile conditions, etc. Due to its high nonlinearity, the torque ripple is high in switched reluctance motor. The sophisticated direct instantaneous torque control (DITC) can maintain the torque developed by the motor within hysteresis band by suitably selecting the switching states of the converter. Hence, DITC controller minimizes the torque ripples and also provides fast response to the torque changes. The performance of DITC controlled SRM drive is analyzed through simulations during acceleration and also in steady state for two types of load torques namely fan type and constant torque. The variation of the switching frequency of the converter is analyzed by changing the torque hysteresis band. It has been observed that as the hysteresis band decreases, the switching frequency increases. So, the hysteresis band cannot be increased beyond a certain limit so as to ensure that the switching frequency of the device cannot increase beyond its operating limit.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Srinivas Pratapgiri",authors:[{id:"193348",title:"Dr.",name:"Srinivas",middleName:null,surname:"Pratapgiri",slug:"srinivas-pratapgiri",fullName:"Srinivas Pratapgiri"}]},{id:"55557",doi:"10.5772/intechopen.69270",title:"Design, Power Electronics and Torque Control of Switched Reluctance Machines",slug:"design-power-electronics-and-torque-control-of-switched-reluctance-machines",totalDownloads:1754,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"In the last decade, increased tendency in the field of automotive industry was focused on the development of highly efficient and low-cost electric propulsion systems to replace the existing internal combustion solutions. The aim is to reduce the pollution due to carbon dioxide emissions into the air. Several electric machine topologies with their power electronics, control and supply units are continuously in the development process to reach the desired goal. One such machine is the switched reluctance machine (SRM), reaching increased power density, low cost and possibility of continuous operation despite fault occurrence. Designing the machine, choosing its power electronics and controlling the machine to diminish the negative effect of the torque ripples are key points in reaching the proper propulsion system. The main topics presented in detail in this chapter are managing the reader’s skills with an analytic design breviary, presenting the machine’s control strategies for instantaneous torque linearization and finally, showing a power converter topology with increased performances in low voltage applications. To be more close to such an application, the exampled machine is developed for a light electric vehicle for people with physical disabilities. Operational skills of the machine will be validated based on complex simulations.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Mircea Ruba and Petre Dorel Teodosescu",authors:[{id:"190371",title:"Dr.",name:"Mircea",middleName:null,surname:"Ruba",slug:"mircea-ruba",fullName:"Mircea Ruba"},{id:"195867",title:"Dr.",name:"Petre",middleName:"Dorel",surname:"Teodosescu",slug:"petre-teodosescu",fullName:"Petre Teodosescu"}]}],mostDownloadedChaptersLast30Days:[{id:"55670",title:"Switched Reluctance Motor Topologies: A Comprehensive Review",slug:"switched-reluctance-motor-topologies-a-comprehensive-review",totalDownloads:4958,totalCrossrefCites:4,totalDimensionsCites:5,abstract:"Switched reluctance motor (SRM) is gaining much interest in industrial applications such as wind energy systems and electric vehicles due to its simple and rugged construction, high‐speed operation ability, insensitivity to high temperature, and its features of fault tolerance. With continued research, different topologies have emerged presenting less torque ripple, high efficiency, high power factor, and high power density. However, there has always been a trade‐off between gaining some of the advantageous and losing some with each new technology. In this chapter, various SRM topologies, design, principle of operation, and respective phase switching schemes are extensively reviewed, and their advantages and drawbacks are discussed. On the other hand, some of SRM limitations (such as excitation penalty, control complexity, noise, and vibration) have prompted research into the incorporation of permanent magnets into the basic SRM structure, and therefore, the chapter also includes discussion on a new class of SRM with permanent magnet assist (PM‐assist) called doubly salient permanent magnet (DSPMM). The DSPM motor incorporates the merits of both the PM brushless motor and the SRM.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Mohammad Mahdi Bouiabady, Aliakbar Damaki Aliabad and\nEbrahim Amiri",authors:[{id:"175468",title:"Dr.",name:"Ebrahim",middleName:null,surname:"Amiri",slug:"ebrahim-amiri",fullName:"Ebrahim Amiri"},{id:"203202",title:"Mr.",name:"Mohammad Mahdi",middleName:null,surname:"Bouiabady",slug:"mohammad-mahdi-bouiabady",fullName:"Mohammad Mahdi Bouiabady"},{id:"203203",title:"Dr.",name:"Aliakbar",middleName:null,surname:"Damaki Aliabad",slug:"aliakbar-damaki-aliabad",fullName:"Aliakbar Damaki Aliabad"}]},{id:"55383",title:"Switched Reluctance Motor Drives for Hybrid Electric Vehicles",slug:"switched-reluctance-motor-drives-for-hybrid-electric-vehicles",totalDownloads:3344,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"Because of the ever‐increasing concerns on the energy utilization and environmental protection, the development of hybrid electric vehicles (HEVs) has become a hot research topic. As the major part of HEV technologies, the electric motor drives have to offer high efficiency, high power density, high controllability, wide‐speed operating range, and maintenance‐free operation. In particular, the switched reluctance (SR) motor drive can achieve most of these goals; therefore, this motor type has drawn much attention in the past. This chapter aims to serve as an overview of the latest developments of the SR motor drive, purposely for HEV applications. To be specific, the discussions on motor structures for torque density enhancement and torque ripple minimization are covered.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Christopher H.T. Lee, James L. Kirtley, Jr. and M. Angle",authors:[{id:"201412",title:"Dr.",name:"Christopher H. T.",middleName:null,surname:"Lee",slug:"christopher-h.-t.-lee",fullName:"Christopher H. T. Lee"}]},{id:"55535",title:"Four‐Quadrant Control of Switched Reluctance Machine",slug:"four-quadrant-control-of-switched-reluctance-machine",totalDownloads:1639,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"This chapter illustrates modeling techniques and software simulation of the switched reluctance machine (SRM) machine models with controllers for efficient operation. The first model is based on torque and flux data generated through finite element analysis (FEA) and the second model is geometry-based machine model, which are used to develop the operation logic for four-quadrant control of an SRM. The results obtained from these models were used to develop a control strategy to adapt turn-on and turn-off (commutation) angles efficiently. Two digital controllers, namely the phase current controller for regulating current with a hysteresis band and the PI (proportional-integral) speed controller for regulating the speed, are developed to deliver the desired output torque. The controller is based on a negative feedback closed-loop control system.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Sandeep Narla",authors:[{id:"201434",title:"M.Sc.",name:"Sandeep",middleName:null,surname:"Narla",slug:"sandeep-narla",fullName:"Sandeep Narla"}]},{id:"55557",title:"Design, Power Electronics and Torque Control of Switched Reluctance Machines",slug:"design-power-electronics-and-torque-control-of-switched-reluctance-machines",totalDownloads:1754,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"In the last decade, increased tendency in the field of automotive industry was focused on the development of highly efficient and low-cost electric propulsion systems to replace the existing internal combustion solutions. The aim is to reduce the pollution due to carbon dioxide emissions into the air. Several electric machine topologies with their power electronics, control and supply units are continuously in the development process to reach the desired goal. One such machine is the switched reluctance machine (SRM), reaching increased power density, low cost and possibility of continuous operation despite fault occurrence. Designing the machine, choosing its power electronics and controlling the machine to diminish the negative effect of the torque ripples are key points in reaching the proper propulsion system. The main topics presented in detail in this chapter are managing the reader’s skills with an analytic design breviary, presenting the machine’s control strategies for instantaneous torque linearization and finally, showing a power converter topology with increased performances in low voltage applications. To be more close to such an application, the exampled machine is developed for a light electric vehicle for people with physical disabilities. Operational skills of the machine will be validated based on complex simulations.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Mircea Ruba and Petre Dorel Teodosescu",authors:[{id:"190371",title:"Dr.",name:"Mircea",middleName:null,surname:"Ruba",slug:"mircea-ruba",fullName:"Mircea Ruba"},{id:"195867",title:"Dr.",name:"Petre",middleName:"Dorel",surname:"Teodosescu",slug:"petre-teodosescu",fullName:"Petre Teodosescu"}]},{id:"55614",title:"Current‐Controlled SRM Fed by Three‐Phase Boost PFC",slug:"current-controlled-srm-fed-by-three-phase-boost-pfc",totalDownloads:1651,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"In this chapter, firstly, converter types of switched reluctance motor (SRM) are described. Current control structure of SRM, which has six stator and four rotor poles, over an asymmetric bridge converter, is also explained. While feeding SRM by an AC grid, grid voltages have to be converted to DC voltage; to realize this conversion, in order to obtain high power factor and sinusoidal grid current, power factor correction (PFC) circuits must be used. In this study, an asymmetric bridge converter of SRM is fed by three‐phase PFC boost converter that consists of uncontrolled diode rectifier and DC‐DC boost converter with high frequency operation. PFC boost converter is controlled by nonlinear control algorithm. By means of the simulations that are conducted by MATLAB/Simulink, grid voltage and current, current harmonics of each phase, three‐phase currents of phases, flux, and current of SRM are presented. Simulation results show that proposed SRM that is fed by three‐phase PFC boost converter system gives the desired performance, for both grid and SRM side.",book:{id:"6017",slug:"switched-reluctance-motor-concept-control-and-applications",title:"Switched Reluctance Motor",fullTitle:"Switched Reluctance Motor - Concept, Control and Applications"},signatures:"Erdal Şehirli and Meral Altınay",authors:[{id:"119997",title:"Mr.",name:"Erdal",middleName:null,surname:"Sehirli",slug:"erdal-sehirli",fullName:"Erdal Sehirli"},{id:"119998",title:"Dr.",name:"Meral",middleName:null,surname:"Altınay",slug:"meral-altinay",fullName:"Meral Altınay"}]}],onlineFirstChaptersFilter:{topicId:"743",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"22",title:"Business, Management and Economics",doi:"10.5772/intechopen.100359",issn:"2753-894X",scope:"\r\n\tThis series will provide a comprehensive overview of recent research trends in business and management, economics, and marketing. Topics will include asset liability management, financial consequences of the financial crisis and covid-19, financial accounting, mergers and acquisitions, management accounting, SMEs, financial markets, corporate finance and governance, managerial technology and innovation, resource management and sustainable development, social entrepreneurship, corporate responsibility, ethics and accountability, microeconomics, labour economics, macroeconomics, public economics, financial economics, econometrics, direct marketing, creative marketing, internet marketing, market planning and forecasting, brand management, market segmentation and targeting and other topics under business and management. This book series will focus on various aspects of business and management whose in-depth understanding is critical for business and company management to function effectively during this uncertain time of financial crisis, Covid-19 pandemic, and military activity in Europe.
",coverUrl:"https://cdn.intechopen.com/series/covers/22.jpg",latestPublicationDate:"June 27th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:1,editor:{id:"356540",title:"Prof.",name:"Taufiq",middleName:null,surname:"Choudhry",slug:"taufiq-choudhry",fullName:"Taufiq Choudhry",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000036X2hvQAC/Profile_Picture_2022-03-14T08:58:03.jpg",biography:"Prof. Choudhry holds a BSc degree in Economics from the University of Iowa, as well as a Masters and Ph.D. in Applied Economics from Clemson University, USA. In January 2006, he became a Professor of Finance at the University of Southampton Business School. He was previously a Professor of Finance at the University of Bradford Management School. He has over 80 articles published in international finance and economics journals. His research interests and specialties include financial econometrics, financial economics, international economics and finance, housing markets, financial markets, among others.",institutionString:null,institution:{name:"University of Southampton",institutionURL:null,country:{name:"United Kingdom"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:3,paginationItems:[{id:"86",title:"Business and Management",coverUrl:"https://cdn.intechopen.com/series_topics/covers/86.jpg",isOpenForSubmission:!0,editor:{id:"128342",title:"Prof.",name:"Vito",middleName:null,surname:"Bobek",slug:"vito-bobek",fullName:"Vito Bobek",profilePictureURL:"https://mts.intechopen.com/storage/users/128342/images/system/128342.jpg",biography:"Dr. Vito Bobek works as an international management professor at the University of Applied Sciences FH Joanneum, Graz, Austria. He has published more than 400 works in his academic career and visited twenty-two universities worldwide as a visiting professor. Dr. Bobek is a member of the editorial boards of six international journals and a member of the Strategic Council of the Minister of Foreign Affairs of the Republic of Slovenia. He has a long history in academia, consulting, and entrepreneurship. His own consulting firm, Palemid, has managed twenty significant projects, such as Cooperation Program Interreg V-A (Slovenia-Austria) and Capacity Building for the Serbian Chamber of Enforcement Agents. He has also participated in many international projects in Italy, Germany, Great Britain, the United States, Spain, Turkey, France, Romania, Croatia, Montenegro, Malaysia, and China. Dr. Bobek is also a co-founder of the Academy of Regional Management in Slovenia.",institutionString:"Universities of Applied Sciences FH Joanneum, Austria",institution:null},editorTwo:{id:"293992",title:"Dr.",name:"Tatjana",middleName:null,surname:"Horvat",slug:"tatjana-horvat",fullName:"Tatjana Horvat",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002hXb0hQAC/Profile_Picture_1642419002203",biography:"Tatjana Horvat works as a professor for accountant and auditing at the University of Primorska, Slovenia. She is a Certified State Internal Auditor (licensed by Ministry of Finance RS) and Certified Internal Auditor for Business Sector and Certified accountant (licensed by Slovenian Institute of Auditors). At the Ministry of Justice of Slovenia, she is a member of examination boards for court expert candidates and judicial appraisers in the following areas: economy/finance, valuation of companies, banking, and forensic investigation of economic operations/accounting. At the leading business newspaper Finance in Slovenia (Swedish ownership), she is the editor and head of the area for business, finance, tax-related articles, and educational programs.",institutionString:null,institution:{name:"University of Primorska",institutionURL:null,country:{name:"Slovenia"}}},editorThree:null},{id:"87",title:"Economics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/87.jpg",isOpenForSubmission:!0,editor:{id:"327730",title:"Prof.",name:"Jaime",middleName:null,surname:"Ortiz",slug:"jaime-ortiz",fullName:"Jaime Ortiz",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00002zaOKZQA2/Profile_Picture_1642145584421",biography:"Dr. Jaime Ortiz holds degrees from Chile, the Netherlands, and the United States. He has held tenured faculty, distinguished professorship, and executive leadership appointments in several universities around the world. Dr. Ortiz has previously worked for international organizations and non-government entities in economic and business matters, and he has university-wide globalization engagement in more than thirty-six countries. He has advised, among others, the United Nations Development Program, Inter-American Development Bank, Organization of American States, Pre-investment Organization of Latin America and the Caribbean, Technical Cooperation of the Suisse Government, and the World Bank. Dr. Ortiz is the author, co-author, or editor of books, book chapters, textbooks, research monographs and technical reports, and refereed journal articles. He is listed in Who’s Who in the World, Who’s Who in America, Who’s Who in Finance and Business, Who’s Who in Business Higher Education, Who’s Who in American Education, and Who’s Who Directory of Economists. Dr. Ortiz has been a Fulbright Scholar and an MSI Leadership Fellow with the W.K. Kellogg Foundation. His teaching interests revolve around global economies and markets while his research focuses on topics related to development and growth, global business decisions, and the economics of technical innovation.",institutionString:null,institution:{name:"University of Houston",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},{id:"88",title:"Marketing",coverUrl:"https://cdn.intechopen.com/series_topics/covers/88.jpg",isOpenForSubmission:!0,editor:{id:"203609",title:"Associate Prof.",name:"Hanna",middleName:null,surname:"Gorska-Warsewicz",slug:"hanna-gorska-warsewicz",fullName:"Hanna Gorska-Warsewicz",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSD9pQAG/Profile_Picture_2022-06-14T11:58:32.jpeg",biography:"Hanna Górska-Warsewicz, Ph.D. is Associate Professor at Warsaw University of Life Sciences and Head of Department of Food Market and Consumption Research. She specializes in the subject of brands, brand equity, and brand management in production, service, and trade enterprises. She combines this subject with marketing and marketing management in both theoretical and practical aspects. Prof. Hanna Górska-Warsewicz also analyzes brands in the context of trademarks, legal regulations and the protection of intangible. She is an author or co-author of over 200 publications in this field, including 8 books. She works with the business sector and has participated in projects for the Ministry of Agriculture and Rural Development and the Ministry of Education and Science in Poland.",institutionString:null,institution:{name:"Warsaw University of Life Sciences",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:8,paginationItems:[{id:"82289",title:"Consumer Culture and Abundance of Choices: Having More, Feeling Blue",doi:"10.5772/intechopen.105607",signatures:"Ondřej Roubal",slug:"consumer-culture-and-abundance-of-choices-having-more-feeling-blue",totalDownloads:2,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"A New Era of Consumer Behavior - Beyond the Pandemic",coverURL:"https://cdn.intechopen.com/books/images_new/11581.jpg",subseries:{id:"88",title:"Marketing"}}},{id:"82405",title:"Does Board Structure Matter in CSR Spending of Commercial Banks? Empirical Evidence from an Emerging Economy",doi:"10.5772/intechopen.105589",signatures:"Bishnu Kumar Adhikary and Ranjan Kumar Mitra",slug:"does-board-structure-matter-in-csr-spending-of-commercial-banks-empirical-evidence-from-an-emerging-",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Corporate Social Responsibility",coverURL:"https://cdn.intechopen.com/books/images_new/11602.jpg",subseries:{id:"86",title:"Business and Management"}}},{id:"82395",title:"Toward a Better Understanding of Green Human Resource Management’s Impact on Green Competitive Advantage: A Conceptual Model",doi:"10.5772/intechopen.105528",signatures:"Hosna Hossari and Kaoutar Elfahli",slug:"toward-a-better-understanding-of-green-human-resource-management-s-impact-on-green-competitive-advan",totalDownloads:12,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Corporate Social Responsibility",coverURL:"https://cdn.intechopen.com/books/images_new/11602.jpg",subseries:{id:"86",title:"Business and Management"}}},{id:"82269",title:"CSR Reporting and Blockchain Technology",doi:"10.5772/intechopen.105512",signatures:"Pattarake Sarajoti, Pattanaporn Chatjuthamard, Suwongrat Papangkorn and Piyachart Phiromswad",slug:"csr-reporting-and-blockchain-technology",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Corporate Social Responsibility",coverURL:"https://cdn.intechopen.com/books/images_new/11602.jpg",subseries:{id:"86",title:"Business and Management"}}}]},overviewPagePublishedBooks:{paginationCount:1,paginationItems:[{type:"book",id:"11392",title:"Leadership in a Changing World",subtitle:"A Multidimensional Perspective",coverURL:"https://cdn.intechopen.com/books/images_new/11392.jpg",slug:"leadership-in-a-changing-world-a-multidimensional-perspective",publishedDate:"May 11th 2022",editedByType:"Edited by",bookSignature:"Muhammad Mohiuddin, Bilal Khalid, Md. Samim Al Azad and Slimane Ed-dafali",hash:"86a6d33cf601587e591064ce92effc02",volumeInSeries:1,fullTitle:"Leadership in a Changing World - A Multidimensional Perspective",editors:[{id:"418514",title:"Dr.",name:"Muhammad",middleName:null,surname:"Mohiuddin",slug:"muhammad-mohiuddin",fullName:"Muhammad Mohiuddin",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038UqSfQAK/Profile_Picture_2022-05-13T10:39:03.jpg",biography:"Dr. Muhammad Mohiuddin is an Associate Professor of International Business at Laval University, Canada. He has taught at Thompson Rivers University, Canada; University of Paris-Est, France; Osnabruck University of Applied Science, Germany; and Shanghai Institute of Technology and Tianjin University of Technology, China. He has published research in Research Policy, Applied Economics, Review of Economic Philosophy, Strategic Change, International Journal of Logistics, Sustainability, Journal of Environmental Management, Journal of Global Information Management, Journal of Cleaner Production, M@N@GEMENT, and more. He is a member of CEDIMES Institut (France), Academy of International Business (AIB), Strategic Management Society (SMS), Academy of Management (AOM), Administrative Science Association of Canada (ASAC), and Canadian council of small business and entrepreneurship (CCSBE). He is currently the director of the Research Group on Contemporary Asia (GERAC) at Laval University. He is also co-managing editor of Transnational Corporations Review and a guest editor for Electronic Commerce Research and Journal of Internet Technology.",institutionString:"Université Laval",institution:{name:"Université Laval",institutionURL:null,country:{name:"Canada"}}}]}]},openForSubmissionBooks:{paginationCount:3,paginationItems:[{id:"11601",title:"Econometrics - Recent Advances and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11601.jpg",hash:"bc8ab49e2cf436c217a49ca8c12a22eb",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"May 13th 2022",isOpenForSubmission:!0,editors:[{id:"452331",title:"Dr.",name:"Brian",surname:"Sloboda",slug:"brian-sloboda",fullName:"Brian Sloboda"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12141",title:"Leadership - Advancing Great Leadership Practices and Good Leaders",coverURL:"https://cdn.intechopen.com/books/images_new/12141.jpg",hash:"85f77453916f1d80d80d88ee4fd2f2d1",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 1st 2022",isOpenForSubmission:!0,editors:[{id:"420133",title:"Dr.",name:"Joseph",surname:"Crawford",slug:"joseph-crawford",fullName:"Joseph Crawford"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12139",title:"Global Market and Trade",coverURL:"https://cdn.intechopen.com/books/images_new/12139.jpg",hash:"fa34af07c3a9657fa670404202f8cba5",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"July 21st 2022",isOpenForSubmission:!0,editors:[{id:"243649",title:"Dr.Ing.",name:"Ireneusz",surname:"Miciuła",slug:"ireneusz-miciula",fullName:"Ireneusz Miciuła"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:10,paginationItems:[{id:"82380",title:"Evolution of Parasitism and Pathogenic Adaptations in Certain Medically Important Fungi",doi:"10.5772/intechopen.105206",signatures:"Gokul Shankar Sabesan, Ranjit Singh AJA, Ranjith Mehenderkar and Basanta Kumar Mohanty",slug:"evolution-of-parasitism-and-pathogenic-adaptations-in-certain-medically-important-fungi",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fungal Infectious Diseases - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11400.jpg",subseries:{id:"4",title:"Fungal Infectious Diseases"}}},{id:"82367",title:"Spatial Variation and Factors Associated with Unsuppressed HIV Viral Load among Women in an HIV Hyperendemic Area of KwaZulu-Natal, South Africa",doi:"10.5772/intechopen.105547",signatures:"Adenike O. Soogun, Ayesha B.M. Kharsany, Temesgen Zewotir and Delia North",slug:"spatial-variation-and-factors-associated-with-unsuppressed-hiv-viral-load-among-women-in-an-hiv-hype",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82193",title:"Enterococcal Infections: Recent Nomenclature and emerging trends",doi:"10.5772/intechopen.104792",signatures:"Kavita Raja",slug:"enterococcal-infections-recent-nomenclature-and-emerging-trends",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"82207",title:"Management Strategies in Perinatal HIV",doi:"10.5772/intechopen.105451",signatures:"Kayla Aleshire and Rima Bazzi",slug:"management-strategies-in-perinatal-hiv",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82013",title:"Streamlining Laboratory Tests for HIV Detection",doi:"10.5772/intechopen.105096",signatures:"Ramakrishna Prakash and Mysore Krishnamurthy Yashaswini",slug:"streamlining-laboratory-tests-for-hiv-detection",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"81972",title:"The Submicroscopic Plasmodium falciparum Malaria in Sub-Saharan Africa; Current Understanding of the Host Immune System and New Perspectives",doi:"10.5772/intechopen.105086",signatures:"Kwame Kumi Asare",slug:"the-submicroscopic-plasmodium-falciparum-malaria-in-sub-saharan-africa-current-understanding-of-the-",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Malaria - Recent Advances, and New Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11576.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"81821",title:"Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination",doi:"10.5772/intechopen.104999",signatures:"Adnan Al-Lahham",slug:"pneumococcal-carriage-in-jordanian-children-and-the-importance-of-vaccination",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"81813",title:"Schistosomiasis: Discovery of New Molecules for Disease Treatment and Vaccine Development",doi:"10.5772/intechopen.104738",signatures:"Andressa Barban do Patrocinio",slug:"schistosomiasis-discovery-of-new-molecules-for-disease-treatment-and-vaccine-development",totalDownloads:14,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"New Horizons for Schistosomiasis Research",coverURL:"https://cdn.intechopen.com/books/images_new/10829.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"81644",title:"Perspective Chapter: Ethics of Using Placebo Controlled Trials for Covid-19 Vaccine Development in Vulnerable Populations",doi:"10.5772/intechopen.104776",signatures:"Lesley Burgess, Jurie Jordaan and Matthew Wilson",slug:"perspective-chapter-ethics-of-using-placebo-controlled-trials-for-covid-19-vaccine-development-in-vu",totalDownloads:22,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"SARS-CoV-2 Variants - Two Years After",coverURL:"https://cdn.intechopen.com/books/images_new/11573.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"80546",title:"Streptococcal Skin and Skin-Structure Infections",doi:"10.5772/intechopen.102894",signatures:"Alwyn Rapose",slug:"streptococcal-skin-and-skin-structure-infections",totalDownloads:64,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}}]},subseriesFiltersForOFChapters:[{caption:"Fungal Infectious Diseases",value:4,count:1,group:"subseries"},{caption:"Parasitic Infectious Diseases",value:5,count:2,group:"subseries"},{caption:"Bacterial Infectious Diseases",value:3,count:3,group:"subseries"},{caption:"Viral Infectious Diseases",value:6,count:4,group:"subseries"}],publishedBooks:{paginationCount:32,paginationItems:[{type:"book",id:"10798",title:"Starch",subtitle:"Evolution and Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/10798.jpg",slug:"starch-evolution-and-recent-advances",publishedDate:"June 28th 2022",editedByType:"Edited by",bookSignature:"Martins Ochubiojo Emeje",hash:"f197f6062c1574a9a90e50a369271bcf",volumeInSeries:33,fullTitle:"Starch - Evolution and Recent Advances",editors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje",profilePictureURL:"https://mts.intechopen.com/storage/users/94311/images/system/94311.jpeg",institutionString:"National Institute for Pharmaceutical Research and Development",institution:{name:"National Institute for Pharmaceutical Research and Development",institutionURL:null,country:{name:"Nigeria"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",slug:"essential-oils-advances-in-extractions-and-biological-applications",publishedDate:"June 23rd 2022",editedByType:"Edited by",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",hash:"742e6cae3a35686f975edc8d7f9afa94",volumeInSeries:32,fullTitle:"Essential Oils - Advances in Extractions and Biological Applications",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira",profilePictureURL:"https://mts.intechopen.com/storage/users/195290/images/system/195290.png",institutionString:"Museu Paraense Emílio Goeldi",institution:{name:"Museu Paraense Emílio Goeldi",institutionURL:null,country:{name:"Brazil"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10839",title:"Protein Detection",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10839.jpg",slug:"protein-detection",publishedDate:"June 23rd 2022",editedByType:"Edited by",bookSignature:"Yusuf Tutar and Lütfi Tutar",hash:"2f1c0e4e0207fc45c936e7d22a5369c4",volumeInSeries:31,fullTitle:"Protein Detection",editors:[{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar",profilePictureURL:"https://mts.intechopen.com/storage/users/158492/images/system/158492.jpeg",institutionString:"University of Health Sciences",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10797",title:"Cell Culture",subtitle:"Advanced Technology and Applications in Medical and Life Sciences",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",slug:"cell-culture-advanced-technology-and-applications-in-medical-and-life-sciences",publishedDate:"June 15th 2022",editedByType:"Edited by",bookSignature:"Xianquan Zhan",hash:"2c628f4757f9639a4450728d839a7842",volumeInSeries:30,fullTitle:"Cell Culture - Advanced Technology and Applications in Medical and Life Sciences",editors:[{id:"223233",title:"Prof.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",profilePictureURL:"https://mts.intechopen.com/storage/users/223233/images/system/223233.png",institutionString:"Shandong First Medical University",institution:{name:"Affiliated Hospital of Shandong Academy of Medical Sciences",institutionURL:null,country:{name:"China"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10841",title:"Hydrolases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10841.jpg",slug:"hydrolases",publishedDate:"June 15th 2022",editedByType:"Edited by",bookSignature:"Sajjad Haider, Adnan Haider and Angel Catalá",hash:"4e868cde273d65a7ff54b1817d640629",volumeInSeries:29,fullTitle:"Hydrolases",editors:[{id:"110708",title:"Dr.",name:"Sajjad",middleName:null,surname:"Haider",slug:"sajjad-haider",fullName:"Sajjad Haider",profilePictureURL:"https://mts.intechopen.com/storage/users/110708/images/system/110708.png",institutionString:"King Saud University",institution:{name:"King Saud University",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10803",title:"Reactive Oxygen Species",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10803.jpg",slug:"reactive-oxygen-species",publishedDate:"April 28th 2022",editedByType:"Edited by",bookSignature:"Rizwan Ahmad",hash:"176adcf090fdd1f93cb8ce3146e79ca1",volumeInSeries:28,fullTitle:"Reactive Oxygen Species",editors:[{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9008",title:"Vitamin K",subtitle:"Recent Topics on the Biology and Chemistry",coverURL:"https://cdn.intechopen.com/books/images_new/9008.jpg",slug:"vitamin-k-recent-topics-on-the-biology-and-chemistry",publishedDate:"March 23rd 2022",editedByType:"Edited by",bookSignature:"Hiroyuki Kagechika and Hitoshi Shirakawa",hash:"8b43add5389ba85743e0a9491e4b9943",volumeInSeries:27,fullTitle:"Vitamin K - Recent Topics on the Biology and Chemistry",editors:[{id:"180528",title:"Dr.",name:"Hiroyuki",middleName:null,surname:"Kagechika",slug:"hiroyuki-kagechika",fullName:"Hiroyuki Kagechika",profilePictureURL:"https://mts.intechopen.com/storage/users/180528/images/system/180528.jpg",institutionString:"Tokyo Medical and Dental University",institution:{name:"Tokyo Medical and Dental University",institutionURL:null,country:{name:"Japan"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10799",title:"Phenolic Compounds",subtitle:"Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10799.jpg",slug:"phenolic-compounds-chemistry-synthesis-diversity-non-conventional-industrial-pharmaceutical-and-therapeutic-applications",publishedDate:"February 23rd 2022",editedByType:"Edited by",bookSignature:"Farid A. Badria",hash:"339199f254d2987ef3167eef74fb8a38",volumeInSeries:26,fullTitle:"Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",institutionString:"Mansoura University",institution:{name:"Mansoura University",institutionURL:null,country:{name:"Egypt"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9659",title:"Fibroblasts",subtitle:"Advances in Inflammation, Autoimmunity and Cancer",coverURL:"https://cdn.intechopen.com/books/images_new/9659.jpg",slug:"fibroblasts-advances-in-inflammation-autoimmunity-and-cancer",publishedDate:"December 22nd 2021",editedByType:"Edited by",bookSignature:"Mojca Frank Bertoncelj and Katja Lakota",hash:"926fa6446f6befbd363fc74971a56de2",volumeInSeries:25,fullTitle:"Fibroblasts - Advances in Inflammation, Autoimmunity and Cancer",editors:[{id:"328755",title:"Ph.D.",name:"Mojca",middleName:null,surname:"Frank Bertoncelj",slug:"mojca-frank-bertoncelj",fullName:"Mojca Frank Bertoncelj",profilePictureURL:"https://mts.intechopen.com/storage/users/328755/images/system/328755.jpg",institutionString:"BioMed X Institute",institution:{name:"University Hospital of Zurich",institutionURL:null,country:{name:"Switzerland"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8977",title:"Protein Kinases",subtitle:"Promising Targets for Anticancer Drug Research",coverURL:"https://cdn.intechopen.com/books/images_new/8977.jpg",slug:"protein-kinases-promising-targets-for-anticancer-drug-research",publishedDate:"December 8th 2021",editedByType:"Edited by",bookSignature:"Rajesh Kumar Singh",hash:"6d200cc031706a565b554fdb1c478901",volumeInSeries:24,fullTitle:"Protein Kinases - Promising Targets for Anticancer Drug Research",editors:[{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8018",title:"Extracellular Matrix",subtitle:"Developments and Therapeutics",coverURL:"https://cdn.intechopen.com/books/images_new/8018.jpg",slug:"extracellular-matrix-developments-and-therapeutics",publishedDate:"October 27th 2021",editedByType:"Edited by",bookSignature:"Rama Sashank Madhurapantula, Joseph Orgel P.R.O. and Zvi Loewy",hash:"c85e82851e80b40282ff9be99ddf2046",volumeInSeries:23,fullTitle:"Extracellular Matrix - Developments and Therapeutics",editors:[{id:"212416",title:"Dr.",name:"Rama Sashank",middleName:null,surname:"Madhurapantula",slug:"rama-sashank-madhurapantula",fullName:"Rama Sashank Madhurapantula",profilePictureURL:"https://mts.intechopen.com/storage/users/212416/images/system/212416.jpg",institutionString:"Illinois Institute of Technology",institution:{name:"Illinois Institute of Technology",institutionURL:null,country:{name:"United States of America"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9759",title:"Vitamin E in Health and Disease",subtitle:"Interactions, Diseases and Health Aspects",coverURL:"https://cdn.intechopen.com/books/images_new/9759.jpg",slug:"vitamin-e-in-health-and-disease-interactions-diseases-and-health-aspects",publishedDate:"October 6th 2021",editedByType:"Edited by",bookSignature:"Pınar Erkekoglu and Júlia Scherer Santos",hash:"6c3ddcc13626110de289b57f2516ac8f",volumeInSeries:22,fullTitle:"Vitamin E in Health and Disease - Interactions, Diseases and Health Aspects",editors:[{id:"109978",title:"Prof.",name:"Pınar",middleName:null,surname:"Erkekoğlu",slug:"pinar-erkekoglu",fullName:"Pınar Erkekoğlu",profilePictureURL:"https://mts.intechopen.com/storage/users/109978/images/system/109978.jpg",institutionString:"Hacettepe University",institution:{name:"Hacettepe University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Proteomics",value:18,count:4},{group:"subseries",caption:"Metabolism",value:17,count:6},{group:"subseries",caption:"Cell and Molecular Biology",value:14,count:9},{group:"subseries",caption:"Chemical Biology",value:15,count:13}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:8},{group:"publicationYear",caption:"2021",value:2021,count:7},{group:"publicationYear",caption:"2020",value:2020,count:12},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:2}],authors:{paginationCount:301,paginationItems:[{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/116250/images/system/116250.jpg",biography:"Professor Nima Rezaei obtained an MD from Tehran University of Medical Sciences, Iran. He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. Govindarajan completed his BSc degree in Zoology at Government Arts College (Autonomous), Kumbakonam, and MSc, MPhil, and PhD degrees at Annamalai University, Annamalai Nagar, Tamil Nadu, India. He is serving as an assistant professor at the Department of Zoology, Annamalai University. His research interests include isolation, identification, and characterization of biologically active molecules from plants and microbes. He has identified more than 20 pure compounds with high mosquitocidal activity and also conducted high-quality research on photochemistry and nanosynthesis. He has published more than 150 studies in journals with impact factor and 2 books in Lambert Academic Publishing, Germany. He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"337446",title:"Dr.",name:"Maria",middleName:null,surname:"Zavala-Colon",slug:"maria-zavala-colon",fullName:"Maria Zavala-Colon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico, Medical Sciences Campus",country:{name:"United States of America"}}},{id:"338856",title:"Mrs.",name:"Nur Alvira",middleName:null,surname:"Pascawati",slug:"nur-alvira-pascawati",fullName:"Nur Alvira Pascawati",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universitas Respati Yogyakarta",country:{name:"Indonesia"}}},{id:"441116",title:"Dr.",name:"Jovanka M.",middleName:null,surname:"Voyich",slug:"jovanka-m.-voyich",fullName:"Jovanka M. Voyich",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Montana State University",country:{name:"United States of America"}}},{id:"330412",title:"Dr.",name:"Muhammad",middleName:null,surname:"Farhab",slug:"muhammad-farhab",fullName:"Muhammad Farhab",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"349495",title:"Dr.",name:"Muhammad",middleName:null,surname:"Ijaz",slug:"muhammad-ijaz",fullName:"Muhammad Ijaz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}}]}},subseries:{item:{id:"20",type:"subseries",title:"Animal Nutrition",keywords:"Sustainable Animal Diets, Carbon Footprint, Meta Analyses",scope:"An essential part of animal production is nutrition. Animals need to receive a properly balanced diet. One of the new challenges we are now faced with is sustainable animal diets (STAND) that involve the 3 P’s (People, Planet, and Profitability). We must develop animal feed that does not compete with human food, use antibiotics, and explore new growth promoters options, such as plant extracts or compounds that promote feed efficiency (e.g., monensin, oils, enzymes, probiotics). These new feed options must also be environmentally friendly, reducing the Carbon footprint, CH4, N, and P emissions to the environment, with an adequate formulation of nutrients.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/20.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11416,editor:{id:"175967",title:"Dr.",name:"Manuel",middleName:null,surname:"Gonzalez Ronquillo",slug:"manuel-gonzalez-ronquillo",fullName:"Manuel Gonzalez Ronquillo",profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",biography:"Dr. Manuel González Ronquillo obtained his doctorate degree from the University of Zaragoza, Spain, in 2001. He is a research professor at the Faculty of Veterinary Medicine and Animal Husbandry, Autonomous University of the State of Mexico. He is also a level-2 researcher. He received a Fulbright-Garcia Robles fellowship for a postdoctoral stay at the US Dairy Forage Research Center, Madison, Wisconsin, USA in 2008–2009. He received grants from Alianza del Pacifico for a stay at the University of Magallanes, Chile, in 2014, and from Consejo Nacional de Ciencia y Tecnología (CONACyT) to work in the Food and Agriculture Organization’s Animal Production and Health Division (AGA), Rome, Italy, in 2014–2015. He has collaborated with researchers from different countries and published ninety-eight journal articles. He teaches various degree courses in zootechnics, sheep production, and agricultural sciences and natural resources.\n\nDr. Ronquillo’s research focuses on the evaluation of sustainable animal diets (StAnD), using native resources of the region, decreasing carbon footprint, and applying meta-analysis and mathematical models for a better understanding of animal production.",institutionString:null,institution:{name:"Universidad Autónoma del Estado de México",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,series:{id:"13",title:"Veterinary Medicine and Science",doi:"10.5772/intechopen.73681",issn:"2632-0517"},editorialBoard:[{id:"175762",title:"Dr.",name:"Alfredo J.",middleName:null,surname:"Escribano",slug:"alfredo-j.-escribano",fullName:"Alfredo J. Escribano",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRGnzQAG/Profile_Picture_1633076636544",institutionString:"Consultant and Independent Researcher in Industry Sector, Spain",institution:null},{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra",profilePictureURL:"https://mts.intechopen.com/storage/users/310962/images/system/310962.jpg",institutionString:null,institution:{name:"West Bengal University of Animal and Fishery Sciences",institutionURL:null,country:{name:"India"}}},{id:"216995",title:"Prof.",name:"Figen",middleName:null,surname:"Kırkpınar",slug:"figen-kirkpinar",fullName:"Figen Kırkpınar",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRMzxQAG/Profile_Picture_1625722918145",institutionString:null,institution:{name:"Ege University",institutionURL:null,country:{name:"Turkey"}}}]},onlineFirstChapters:{paginationCount:2,paginationItems:[{id:"82392",title:"Nanomaterials as Novel Biomarkers for Cancer Nanotheranostics: State of the Art",doi:"10.5772/intechopen.105700",signatures:"Hao Yu, Zhihai Han, Cunrong Chen and Leisheng Zhang",slug:"nanomaterials-as-novel-biomarkers-for-cancer-nanotheranostics-state-of-the-art",totalDownloads:21,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11405.jpg",subseries:{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering"}}},{id:"81778",title:"Influence of Mechanical Properties of Biomaterials on the Reconstruction of Biomedical Parts via Additive Manufacturing Techniques: An Overview",doi:"10.5772/intechopen.104465",signatures:"Babatunde Olamide Omiyale, Akeem Abiodun Rasheed, Robinson Omoboyode Akinnusi and Temitope Olumide Olugbade",slug:"influence-of-mechanical-properties-of-biomaterials-on-the-reconstruction-of-biomedical-parts-via-add",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11405.jpg",subseries:{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering"}}}]},publishedBooks:{paginationCount:7,paginationItems:[{type:"book",id:"7102",title:"Pneumonia",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7102.jpg",slug:"pneumonia",publishedDate:"May 11th 2022",editedByType:"Edited by",bookSignature:"Nima Rezaei",hash:"9fd70142814192dcec58a176749f1b60",volumeInSeries:13,fullTitle:"Pneumonia",editors:[{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei",profilePictureURL:"https://mts.intechopen.com/storage/users/116250/images/system/116250.jpg",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",institutionURL:null,country:{name:"Iran"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9615",title:"Chikungunya Virus",subtitle:"A Growing Global Public Health Threat",coverURL:"https://cdn.intechopen.com/books/images_new/9615.jpg",slug:"chikungunya-virus-a-growing-global-public-health-threat",publishedDate:"February 9th 2022",editedByType:"Edited by",bookSignature:"Jean Engohang-Ndong",hash:"c960d94a63867dd12a8ab15176a3ff06",volumeInSeries:12,fullTitle:"Chikungunya Virus - A Growing Global Public Health Threat",editors:[{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",institutionString:"Kent State University",institution:{name:"Kent State University",institutionURL:null,country:{name:"United States of America"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9619",title:"Epstein-Barr Virus",subtitle:"New Trends",coverURL:"https://cdn.intechopen.com/books/images_new/9619.jpg",slug:"epstein-barr-virus-new-trends",publishedDate:"December 22nd 2021",editedByType:"Edited by",bookSignature:"Emmanuel Drouet",hash:"a2128c53becb6064589570cbe8d976f8",volumeInSeries:11,fullTitle:"Epstein-Barr Virus - New Trends",editors:[{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",institutionString:null,institution:{name:"Grenoble Alpes University",institutionURL:null,country:{name:"France"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9613",title:"Dengue Fever in a One Health Perspective",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9613.jpg",slug:"dengue-fever-in-a-one-health-perspective",publishedDate:"October 28th 2020",editedByType:"Edited by",bookSignature:"Márcia Aparecida Sperança",hash:"77ecce8195c11092230b4156df6d83ff",volumeInSeries:7,fullTitle:"Dengue Fever in a One Health Perspective",editors:[{id:"176579",title:"Dr.",name:"Márcia Aparecida",middleName:null,surname:"Sperança",slug:"marcia-aparecida-speranca",fullName:"Márcia Aparecida Sperança",profilePictureURL:"https://mts.intechopen.com/storage/users/176579/images/system/176579.jpg",institutionString:null,institution:{name:"Universidade Federal do ABC",institutionURL:null,country:{name:"Brazil"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7887",title:"Hepatitis B and C",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7887.jpg",slug:"hepatitis-b-and-c",publishedDate:"April 8th 2020",editedByType:"Edited by",bookSignature:"Luis Rodrigo",hash:"8dd6dab483cf505d83caddaeaf497f2c",volumeInSeries:5,fullTitle:"Hepatitis B and C",editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo",profilePictureURL:"https://mts.intechopen.com/storage/users/73208/images/system/73208.jpg",institutionString:"University of Oviedo",institution:{name:"University of Oviedo",institutionURL:null,country:{name:"Spain"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7064",title:"Current Perspectives in Human Papillomavirus",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7064.jpg",slug:"current-perspectives-in-human-papillomavirus",publishedDate:"May 2nd 2019",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"d92a4085627bab25ddc7942fbf44cf05",volumeInSeries:2,fullTitle:"Current Perspectives in Human Papillomavirus",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"6667",title:"Influenza",subtitle:"Therapeutics and Challenges",coverURL:"https://cdn.intechopen.com/books/images_new/6667.jpg",slug:"influenza-therapeutics-and-challenges",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"105e347b2d5dbbe6b593aceffa051efa",volumeInSeries:1,fullTitle:"Influenza - Therapeutics and Challenges",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.png",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}},{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}}]},submityourwork:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],subseriesList:[{id:"14",title:"Cell and Molecular Biology",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression"},{id:"15",title:"Chemical Biology",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors"},{id:"17",title:"Metabolism",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation"},{id:"18",title:"Proteomics",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:null},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"profile.detail",path:"/profiles/76156",hash:"",query:{},params:{id:"76156"},fullPath:"/profiles/76156",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()