Part of the book: Lasers
This chapter provides an overview of recent advances in the field of laser-based synthesis of biopolymer thin films for biomedical applications. The introduction addresses the importance of biopolymer thin films with respect to several applications like tissue engineering, cell instructive environments, and drug delivery systems. The next section is devoted to applications of the fabrication of organic and hybrid organic–inorganic coatings. Matrix-assisted pulsed laser evaporation (MAPLE) and Combinatorial-MAPLE are introduced and compared with other conventional methods of thin films assembling on solid substrates. Advantages and limitations of the methods are pointed out by focusing on the delicate transfer of bio-macromolecules, preservation of properties and on the prospect of combinatorial libraries’ synthesis in a single-step process. The following section provides a brief description of fundamental processes involved in the molecular transfer of delicate materials by MAPLE. Then, the chapter focuses on the laser synthesis of two polysaccharide thin films, namely Dextran doped with iron oxide nanoparticles and Levan, followed by an overview on the MAPLE synthesis of other biopolymers. The chapter ends with summary and perspectives of this fast-expanding research field, and a rich bibliographic database.
Part of the book: Recent Advances in Biopolymers
Active under visible light, photocatalysts based on doped titania were obtained via pulsed laser deposition (PLD) method. To find out the crystalline structure, optical properties, and electronic structure, the following techniques such as X-ray diffraction, electronic spectroscopy, electrical conductivity measurements, and X-ray photoelectron spectroscopy (XPS) are used. Photocatalytic activity is monitored by applying the photoreduction of dichromate ions under UV and visible light. The influence of zirconium ions and its content and synthesis conditions on the efficiency of nitrogen incorporation into titania structure that, in turn, determines the electronic structure and photocatalytic ability of the semiconductive materials are discussed. A substitutional nitrogen (Ti–N) rather than an interstitial one (Ti–O–N) is mainly responsible for the observed photoactivity. It is pointed that substitutional nitrogen is responsible for bandgap narrowing or formation of intragap localized states within semiconductor bandgap. The bandgap energy values are sharply decreased, while the relative intensity of substitutional nitrogen XPS peaks is increased. Pulsed laser synthesis of TiO2 films in N2/CH4 atmosphere not only leads to nitrogen incorporation but also to the formation of defects including oxygen vacancies and Ti3+ states which are all contributing to light absorption. An appropriate ratio of gas mixture, optimum zirconia content, suitable pressure, and temperature during synthesis was found for the synthesis of highly active semiconductive films. The highest photocatalytic conversion yields are obtained for nitrogen-doped 10% ZrO2/TiO2 synthesized in N2:CH4 = 5:1 at 100 Pa and at 450°C under both UV and visible light.
Part of the book: Semiconductor Photocatalysis
This chapter reviews the progress and perspectives of composite materials in the form of thin films based on renewable resources for biofabrication of a new generation of medical implants with antibacterial properties. The chapter starts with an overview of the types of renewable materials that were currently studied and of the unique properties which make them perfect candidates for numerous bio‐related applications. A briefing of recent progresses in the field of advanced laser synthesis of composites from renewable and sustainable materials, as well as the relevant results in our researches is made. The discussion spans composite coatings based on renewable resources, [e.g., chitosan (CHT) and lignin (Lig)] as biomaterials intended for metallic implants. A particular attention is given to lignin synthesis in the form of thin films due to its ability to functionalize the medical implant surface while preserving the similar composition and the structural properties of the raw, renewable biomaterial. We focused on recent technological advancements (e.g., matrix‐assisted pulsed laser evaporation (MAPLE) and Combinatorial‐MAPLE) which have brought the spotlight onto renewable biomaterials, by detailing the relevant engineering data of processing. This chapter concludes that the extensions of advanced laser techniques are viable fabrication methods of a new generation of metallic implants.
Part of the book: Composites from Renewable and Sustainable Materials
This chapter reviews the laser ablation of delicate organic/biological substances by matrix-assisted pulsed laser evaporation (MAPLE). It is shown that direct ablation in this case is possible but sometimes not workable at all in adverse conditions. The considered solution is the protection by a prevalent dissolving/suspending component that can allow for a “shielded” ablation by the frozen solvent followed by its gradual evaporation by melting, evaporation and evacuation by pumping system. We extend the study to the case of non-UV absorbing solvents, e.g., water, when the primary interaction between laser and solute ignites evaporation process at a lower ablation threshold due to reduced pressure inside irradiation chamber. We called this case as “generalized” MAPLE interaction. Relevant examples are provided and critically analyzed in view of potential applications for nanobiomedicine, biosensors, advanced implants and chemical technologies.
Part of the book: Laser Ablation