Chapters authored
Supercritical Carbon Dioxide Facilitated Collagen Scaffold Production for Tissue Engineering
The rise of tissue engineering and regenerative medicine (TERM) is a developing field that focuses on the advancement of alternative therapies for tissue and organ restoration. Collagen scaffold biomaterials play a vital role as a scaffold to promote cell growth and differentiation to promote the repair and regenerate the tissue lesion. The goal of this chapter will be to evaluate the role of supercritical carbon dioxide extraction technology in the production of collagen scaffold biomaterials from various tissues and organs and relate it to the traditional decellularization techniques in the production of collagen biomaterials for TERM. Therefore, we will study the collagen scaffold biomaterials produced using supercritical carbon dioxide extraction technology and their characteristics, such as chemical-physical properties, toxicity, biocompatibility, in vitro and in vivo bioactivity that could affect the interaction with cells and living system, relative to traditional decellularization technique-mediated collagen scaffolds. Furthermore, the chapter will focus on supercritical carbon dioxide extraction technology for the production of collagen scaffolds biomaterial appropriate for TERM.
Part of the book: Collagen Biomaterials