\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
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In 2002, Dr. Li started to study the telomere structure and functions in a protozoan parasite, Trypanosoma brucei, which causes human African trypanosomiasis. Dr. Li joined Cleveland State University in 2006 and became a tenured associate professor in 2011. Her work has led to the identification of T. brucei telomere proteins TRF and RAP1. She has shown that T. brucei RAP1 plays an essential role in silencing virulence genes located adjacent to telomeres, demonstrating for the first time that the telomere complex plays an important role in T. brucei pathogenesis and virulence regulation (Yang et al. 2009. 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Engineering",slug:"collagen-based-drug-delivery-systems-for-tissue-engineering",signatures:"Mădălina Georgiana Albu, Irina Titorencu and Mihaela Violeta Ghica",authors:[{id:"50060",title:"Dr.",name:"Madalina Georgiana",middleName:null,surname:"Albu",fullName:"Madalina Georgiana Albu",slug:"madalina-georgiana-albu"},{id:"56578",title:"Dr.",name:"Irina",middleName:null,surname:"Titorencu",fullName:"Irina Titorencu",slug:"irina-titorencu"},{id:"56579",title:"Dr.",name:"Mihaela Violeta",middleName:null,surname:"Ghica",fullName:"Mihaela Violeta Ghica",slug:"mihaela-violeta-ghica"}]},{id:"23633",title:"The Use of Biomaterials to Treat Abdominal Hernias",slug:"the-use-of-biomaterials-to-treat-abdominal-hernias",signatures:"Luciano Zogbi",authors:[{id:"56634",title:"Dr.",name:"Luciano",middleName:null,surname:"Zogbi",fullName:"Luciano Zogbi",slug:"luciano-zogbi"}]},{id:"23634",title:"Biopolymers as Wound Healing Materials: Challenges and New Strategies",slug:"biopolymers-as-wound-healing-materials-challenges-and-new-strategies",signatures:"Ali Demir Sezer and Erdal Cevher",authors:[{id:"62389",title:"PhD.",name:"Ali Demir",middleName:null,surname:"Sezer",fullName:"Ali Demir Sezer",slug:"ali-demir-sezer"},{id:"129634",title:"Prof.",name:"Erdal",middleName:null,surname:"Cevher",fullName:"Erdal Cevher",slug:"erdal-cevher"}]},{id:"23635",title:"Cellular Systems and Biomaterials for Nerve Regeneration in Neurotmesis Injuries",slug:"cellular-systems-and-biomaterials-for-nerve-regeneration-in-neurotmesis-injuries",signatures:"Ana Colette Maurício, Andrea Gärtner, Paulo Armada-da-Silva, Sandra Amado, Tiago Pereira, António Prieto Veloso, Artur Varejão, Ana Lúcia Luís and Stefano Geuna",authors:[{id:"48118",title:"Prof.",name:"Stefano",middleName:null,surname:"Geuna",fullName:"Stefano Geuna",slug:"stefano-geuna"},{id:"56285",title:"Prof.",name:"Ana Colette",middleName:null,surname:"Maurício",fullName:"Ana Colette 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Suckow, Rae Ritchie and Amy Overby",authors:[{id:"56475",title:"Dr.",name:"Mark",middleName:null,surname:"Suckow",fullName:"Mark Suckow",slug:"mark-suckow"},{id:"56502",title:"Dr.",name:"Rae",middleName:null,surname:"Ritchie",fullName:"Rae Ritchie",slug:"rae-ritchie"},{id:"56503",title:"Ms",name:"Amy",middleName:null,surname:"Overby",fullName:"Amy Overby",slug:"amy-overby"}]}]}],publishedBooks:[{type:"book",id:"395",title:"Biomaterials",subtitle:"Physics and Chemistry",isOpenForSubmission:!1,hash:"41507bb56706aec99bb59a645585d54e",slug:"biomaterials-physics-and-chemistry",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/395.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1486",title:"Biomaterials Science and Engineering",subtitle:null,isOpenForSubmission:!1,hash:"38aeff8880e6259e624707abda269b0f",slug:"biomaterials-science-and-engineering",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/1486.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1487",title:"Biomaterials",subtitle:"Applications for Nanomedicine",isOpenForSubmission:!1,hash:"696e143e9bcc2385c45795c2d73cdafc",slug:"biomaterials-applications-for-nanomedicine",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/1487.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7727",title:"Biotechnology and Bioengineering",subtitle:null,isOpenForSubmission:!1,hash:"1e6603fadccf154db3bc2b7a1e473121",slug:"biotechnology-and-bioengineering",bookSignature:"Eduardo Jacob -Lopes and Leila Queiroz Zepka",coverURL:"https://cdn.intechopen.com/books/images_new/7727.jpg",editedByType:"Edited by",editors:[{id:"171980",title:"Dr.",name:"Eduardo",surname:"Jacob-Lopes",slug:"eduardo-jacob-lopes",fullName:"Eduardo Jacob-Lopes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6280",title:"Biomaterials",subtitle:"Physics and Chemistry - 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Some of their most important characteristics that necessitate their use in these applications are lightness, ease of processing, resistance to corrosion, transparency, and others. Nevertheless, their wide use in various applications in combination with the short life span of many plastic products leads to large amounts of end-of-life plastics. Taking all these into account, along with plastic nonbiodegradability, research has focused on exploring environmentally friendly approaches for their safe disposal [2]. Plastic handling involves collection, treatment, and afterward recycling. Unfortunately, finding environmentally friendly approaches for their disposal is no mean feat (Figure 1); due to the variation in types of plastics, which are often of unknown composition, the existence of polymer blends, or composites, multilayer structures with other materials apart from polymers, as well as the wide range of additives (such as UV and thermal stabilizers, antistatic agents, (brominated) flame retardants, colorants, plasticizers, etc.) they may contain [3, 4].
Difficulties encountered during end-of-life plastic handling.
The disposal of post-consumer plastics occurs via landfilling, primary recycling, energy recovery, mechanical recycling, and chemical recycling [2]. Although landfilling is an undesirable, non-recycling method, since it results in serious environmental problems, such as soil and groundwater contamination, until now large amounts of end-of-life plastics still end up in landfilling [5, 6]. With a view to eliminating plastic landfilling, research has focused on recycling methods (Figure 2) that can be applied, which are primary recycling, recycling without quality losses, energy recovery-quaternary, mechanical or secondary recycling-downcycling into lower qualities and chemical or tertiary recycling-recovery of chemical constituents [7]:
In primary recycling (re-extrusion), the plastic scrap is reinserted in the heating cycle of the processing line in order to increase the production [8]. It remains a very popular method, because of its simplicity and low cost. However, it can be applied only in case of clean, uncontaminated single-type waste [2].
Mechanical recycling involves reprocessing and modification of plastic waste using mechanical-physical means with the aim of forming similar, plastic products, at nearly the same or lower performance level when compared with the original products [6]. Since mechanical recycling can be used only in case of homogeneous plastics, heterogeneous plastics require sorting and separation before their recycling. In mechanical recycling, the presence of brominated flame retardant (BFR) incorporated in plastics must be identified before its application, in order to avoid the possible formation of toxic substances, such as polybrominated dibenzo-p-dioxins/furans (PBDD/Fs) [9, 10]. Its main drawback is the fact that product’s properties are deteriorated during every cycle [2]; and it should be underlined that each polymer can endure only a limited number of reprocessing cycles [11]. An additional challenge is the existence of mixed plastic waste (polymer blends), since different polymer types have different melting points and processing temperatures. In such cases, the processing temperature is usually set to the highest melting component. Nevertheless, this may result in overheating and possible degradation of the lower melting components and so, in reduced final properties [12].
In chemical or feedstock recycling, plastic wastes are converted into lower-molecular-weight products, such as: fuels, monomers, or secondary valuable products that can be used as feedstock for refineries. Conversion takes place through chemical reactions in the presence of solvents and reagents [10]. It is an environmentally friendly method, since, as mentioned previously, it results in the formation of valuable products or monomers [9].
During energy recovery, plastics are incinerated in a boiler or in other industrial equipment, taking advantage of their high energy value; for energy production in the form of heat and electricity. Nevertheless, if incomplete incineration takes place, then toxic substances, such as dioxins, furans, and others, may be formed and released into the atmosphere, resulting in environmental issues [2, 8, 9, 10].
Recycling methods for post-consumer plastics.
In conclusion, during chemical recycling, plastics are converted into smaller molecules (mainly liquids and gases), which can be used for the production of new, valuable products; and that is why it is considered as an environmentally friendly and economically feasible technique. Furthermore, chemical recycling seems to be more advantageous than the other existing methods; taking into account, for instance, the fact that during chemical recycling, both heterogeneous and contaminated polymers can be treated, only with a limited pretreatment. Moreover, the energy consumption of the process is very low, if compared with that of mechanical recycling or energy recovery [6].
Chemical recycling comprises two processes: solvolysis and thermolysis. During solvolysis, polymers are dissolved in a solvent and treated with or without catalysts and initiators.
Chemical recycling routes.
Generally, it should be underlined that pyrolysis can be considered as one of the best options for plastics recycling, since its advantages are aplenty. Specifically, pyrolysis enables material and energy recovery from polymer waste, as a very small amount of the energy content of waste is consumed for its conversion into valuable hydrocarbons. Furthermore, pyrolysis products are valuable, since they can be used as fuels or chemical feedstock. Last but not least, in case that flame retardants are present in plastic waste, via pyrolysis the formation of toxic substances may be restricted, due to the fact that it takes place in the absence of oxygen [17]. Of course, catalyst’s presence, as mentioned previously, plays a vital role. Apart from catalysts, various other parameters, including temperature, heating rate, residence time, operating pressure, etc., can strongly affect the quality and distribution of pyrolysis products [6].
As mentioned previously, many obstacles can be found during the end-of-life plastic recycling. In this unit there are presented in detail three case studies, including: polymeric blends (difficulties due to the coexistence of mixed plastic wastes), plastics originating in multilayer packaging (challenging because of the coexistence of different materials, such as plastics, paper, and metals), and brominated flame-retarded plastics from WEEE (possible formation of undesirable, toxic substances due to the BFR’s presence), along with suggestions on how to overcome these difficulties.
Polymer blends are mixtures of two or more polymers in concentration greater than 2%wt. The blends can be miscible or immiscible, a parameter that depends on the thermodynamics of the system and molecular structure, weight, and polymer concentration. More information on the complicated thermodynamics that govern polymer blend miscibility can be found in the Polymer Blends Handbook [18, 19]. Miscible polymer blends are also known as homogeneous blends and are monophasic while immiscible blends with morphologies that differ such as, spheres, cylinders, fibers, or sheets (Figure 4) [12].
(a) and (b) are a visual representation of the differences between miscible and immiscible Polymer Blends. Images (c), (d), and (e) show the spherical, fibrous, and cylindrical morphologies of immiscible Polymer Blends, respectively. Image inspired by Ragaert et al. [
Subject to polymer compatibility, polymer blends can exhibit synergistic, antagonistic, or additive behavior. A common method used to assuage the immiscibility of polymers blends is the inclusion of compatibilizers—a polymeric surface tension reduction agent that promotes interfacial adherence—in the blend. The three most common types of compatibilizers are reactive functionalized polymers, nonreactive polymers containing polar groups, and block or graft polymers [12, 19, 20].
The difficulty during polymer blend recycling lies in the different properties presented by its component parts such as melting points and processing temperatures between polymers [12]. Most recycling efforts are concentrated on the procedure of pyrolysis to extract energy through the oils, wax, char, and gasses produced. Furthermore, research in recent years has focused on the use of various, different catalysts in order to lower the energy consumption of the whole process and increase the exploitable yield. Along with those some novel methods of polymer blend recycling will be explored.
Polymer composites are made up of two or more elements resulting in a multiphase, multicomponent system that exhibits superior properties compared with the constituent materials due to a synergistic effect. It comprises two parts:
A polymeric matrix that can be either thermoplastic polymers such as polypropylene (PP), polycarbonate (PC), acrylonitrile-butadiene-styrene (ABS) and poly(ethylene terephthalate) (PET) or thermoset polymers such as epoxy, vinyl ester, and polyester.
A reinforcing filler such as glass, carbon, and aramid [21].
One way that polymer blend can be recycled is by acting as the matrix for secondary elements creating composite materials. In this way it is possible to unite the two components in a form that reinforces the secondary materials and reuses the polymer blends. This method can be adapted to use natural fillers or fibers as the reinforcing fillers. Those can be added along with a coupling agent to optimize the interaction of the fillers with the matrix further and have the positive side effect of making the whole process environmentally friendly. It is important, however, that these fillers have the capacity to be chemically treated.
In a research conducted by Choudory et al., [22], Low-density polyethylene (LDPE)/Linear low-density polyethylene (LLDPE) blend extracted from milk pouches was used as a matrix for coir fibers. The result was composites with properties only slightly lacking from the virgin material ones. In case a maleated styrene pretreatment was applied, the mechanical properties and thermooxidative stability were drastically increased [23].
In another research conducted by Lou et al., [24], PET/PP blend and bamboo charcoal were used to create extruded or injection-molded composite materials. A great increase in mechanical properties was observed in the injection-molded composites, which maintained their mechanical properties even after three rounds of processing. The percentage of total mass of PET in the blend plays a particularly significant role in the product’s final behavior [23].
Pyrolysis is a promising choice as regards the recycling of polymer blends. With pyrolysis, high levels of conversion of the polymer blend into oil and gas with high calorific values can be attained. These can be used afterward to either fuel the process, or they can be utilized elsewhere [25]. This can be an invaluable asset to the petrochemical industry and a green way for the recycling of plastic waste [26].
Another advantage of pyrolysis is that a sorting process is not needed in contrast to other recycling methods that are extremely susceptible to contamination. This can of course save money and time when recycling polymer blends. Lastly, with the use of the pyrolysis procedure, waste management becomes easier as it is a cheap and environmentally friendly method. In the meanwhile, it allows for minimization of landfill capacity—a serious contemporary difficulty [5]. As the combination of polymers that make up polymer blends is wide, with every blend presenting different properties and pyrolysis behavior, it would be impractical to analyze each one of them. Instead, this chapter will focus on the pyrolysis route taken for the most common polymer blends by examining the research conducted by scientists in the field.
In general, the pyrolysis process can be either thermal or catalytic. In practice, however, the latter is widely preferred by the industry as it demands lower operating temperatures—and thus cost is minimized—that produce a more satisfactory yield of pyrolytic oils, if the correct catalyst has been elected [5].
In a study conducted by Vasile et al., [26], a blend with a composition similar to that originating in municipal waste—24%wt high-density polyethylene (HDPE), 39%wt LDPE, 21.5%wt isotactic polypropylene (IPP), 10%wt PS, 4%wt ABS, and 1.5%wt PET—was investigated. The blend underwent the process of catalytic pyrolysis two separate times each with a different catalyst—HZSM-5 in the first batch and PZSM-5 zeolite catalyst in the second batch, in order to find which catalyst led to better results. It was concluded that the PZSM zeolitic catalyst was characterized by higher selectivity and stability. The optimal temperature for the pyrolysis was found to be 450–480°C, and the gas produced increased sixfold in comparison to the non-catalytic process. Furthermore, the liquid products were found to contain high concentrations of aromatic hydrocarbons. As such, both the liquid and the gas phase can be utilized by the petrochemical industry. Lastly, the pyrolysis oil could be useful as petrochemical feedstock [26].
A novel research conducted by Bober et al. [27] proposed a way to produce hydrogen gas from the catalytic pyrolysis of different consistency HDPE/ poly(methyl methacrylate) PMMA polymer blends. After trial and error, the optimal temperature for maximum hydrogen production was found to be 815°C, a temperature where the catalyst used, Ni/Co, operated the best for hydrogen production. It was also found that, the higher the HDPE content in the blend, the bigger the hydrogen output. In contrast, when PMMA was the dominant polymer in the blend, CO was produced at a greater rate than the previous procedure. The research team proposed that the best ratio for HDPE/PMMA in the blend is 4:1 [27].
It must also be noted that concerning the production of hydrogen from pyrolysis of polymer blends, a popular option is the co-pyrolysis of the polymer blends with biomass [28].
A largely untapped potential of Polymer Blends is their recycling as feedstock for the chemical industry. A study presented by Plastics Europe [29], displays that only 2–3% of the collected plastic waste in Europe is utilized as feedstock (Figure 5).
The fate of the European collected plastic waste. Image inspired by Donaj et al. [
A possible procedure for the creation of feedstock from pyrolysis of Polymer Blends on the group of polyolefins was suggested by Donaj et al., [30]. For the purposes of the process, the researchers used a blend of polyolefins—46% LDPE, 30% HDPE, 24% PP- taken from MSW/plastic waste. The collected material was firstly reduced in size to about 3 mm pieces and then pyrolysis ensued under temperatures of 600–700°C in a fluidized bed reactor and with the use of steam and a catalyst if that was deemed feasible as the latter materials increase the yield of olefines. To optimize the procedure, Ziegler-Natta catalyst was used.
The research noted that after the procedure’s conclusion, plastic pyrolysis had directly yielded 15–30% gaseous olefins that can then be channeled directly into a polymerization plant. The residue produced consists of a naphtha-like consistency. To be used, this residue must undergo reformation via petrochemical technologies to be upgraded into olefins. Also, as in the previous cases of pyrolysis, the products of the process can be used to fuel the procedure itself. However, work still needs to be done on this field as the process described is not as cost-effective as desired [30].
A last noteworthy method for the utilization of immiscible Polymer Blends is their direct melting processing into fibers with good mechanical properties proposed by Shi et al. [31]. The blend used in this research was PS/PP while fibers were chosen due to two distinct reasons: (a) The fiber spinning technique is known to endow improved properties to polymer blends. (b) Fibers from polymer blends may display new properties in comparison to pure polymers. This method is widely cost-effective for preparing strong fibers for the industry, and it is expected to see great development in the coming years [31].
In this age of climate change and overall pollution, it has been the priority of policymakers to ensure the viable and sustainable future of human development. An example of this is the EU with the European Plastic Strategy dictating that all packaging used should be reusable or recyclable by 2030 [32].
A prime example of the challenges the industry faces to reach this standard is Tetra Pak, a multilayer packaging used mostly in the food, medicine, chemical, and commodities industry. Tetra Pak most usually consists of three elements: paper cardboard, aluminum, and LDPE.
As stated by the Tetra Pak company, its composition is as follows: (a) 71% paperboard, (b) 24% plastics, and (c) 5% aluminum foil (Figures 6 and 7).
Raw materials used to produce Tetra Pak. Image inspired by the Tetra Pak site information.
The layers of Tetra Pak. Image inspired by Georgiopoulou et al. [
These three make up the six layers that combined make Tetra Pak. Each layer has a particular use elaborated on below:
However, this is not an absolute rule. For example, certain products with a short shelf life have no need for the protection given by the aluminum layer. On the other hand, when the aforementioned shelf life needs to be extended, the LDPE layers can be substituted by PP providing a chance for further heat treatment of the product. HDPE, PET, and PA are also possible options for replacing the LDPE layers. Lastly, polyurethanes and EMAA are often utilized as adhesives between layers [34] while the Tetra Pak carton may also contain various chemical additives such as plasticizers, stabilizers, lubricants, fillers, foaming agents, colorants, flame retardants, and antistatic agents [35].
As Tetra Pak cartons are composed of mainly paper, the removal and recycling of the carboard layer are of much significance. As such there are two main processing routes: recycling without hydropulping and recycling with hydropulping. The initial procedure processes the cartons as a whole, while the latter uses the technique of hydropulping to first separate the cellulosic fibers from the Al-LDPE laminate.
The main aim of those following this route is energy recovery or downcycling. Energy recovery is attained in combination with solid municipal waste through means of pyrolysis, gasification, or incineration. However, this method comes with many downsides. Paper—the main ingredient of Tetra Pak cartons—has a low heat combustion (16 MJ/Kg), high moisture content, and a significantly high ash value. This makes the entire process inefficient, and thus it is in general not widely used [34].
Before proceeding with the options in this category, it would be useful to briefly go over the hydropulping process. When the soon-to-be recycled material first arrives into the recycle unit, the hydropulper breaks apart the paper with rotating blades that use high pressure water and a slurry of fibers is produced. Further processing ensues in centrifugal cleaners that remove heavy materials such as sand, adhesives, staples, etc. [36]. The end result of this procedure is a pulp of cellulosic fibers and can be used as a substitute for wood pulp, in the production of brown paper and pulp board [37]. What remains after the process is the external LDPE layer and the Al-LDPE laminates. However, residual cellulosic fibers can account for up to 5% of the finished products (Figure 8).
The main recycling routes.
The appeal of this method lies in its simplicity and cost-effectiveness. The pyrolysis procedure has two steps: (a) the degradation of paper (200–400°C) and (b) the devolatilization of LDPE (420–515°C) [38, 39, 40]. It should be noted that the temperature plays an important role in the composition of the final products. For example, the production of char is minimized with higher temperatures, and the opposite is true for wax.
The solid products that follow the process are aluminum, char caused by paper degradation, wax from LDPE degradation and tar. A great deal of gaseous products are also formed that mainly consist of CO2, CO, H2, CH4, C2–6 hydrocarbons, and volatile matter. Lastly, there is an aqueous phase consisting of water and phenols.
Many uses have been proposed for those pyrolytic products. The produced gases could be used to sustain the pyrolysis procedure itself or used elsewhere entirely, the char and tar can be exploited as a solid and oil fuel, respectively, while char can also act as a primal resource for the production of carbon-based materials. Lastly, the wax and aqueous phase can readily be utilized as a raw material for the chemical industry [39, 40].
A novel approach has been taken by researchers in Mexico and Spain who have used the char and the aluminum from the pyrolysis to have them act as absorbents of mercury in aqueous solutions. By means of trial and error and using thermodynamical analyses, they did conclude that char obtained from pyrolysis at 600°C at a 3 h procedure demonstrated the most promising mercury adsorption capacity at 21.0 mg/g. The field of char absorbents is still expanding with hopes of Tetra Pak pyrolysis chars acting as major absorbents for industry in the future [41].
The basic principle of this approach is the immersion of the Al-PE laminate in a carefully selected solvent and under specific temperature conditions with the aim of the dissolution of the LDPE in the solvent. What follows is the removal by means of filtration of additives and impurities. Lastly an antisolvent is added, and as a result precipitation of the dissolved polymer follows. To maximize LDPE and pure aluminum recovery, the SDP process is repeated three times.
The LDPE produced is of quality that matches that of the virgin product while the aluminum collected is also of high purity. Along with the hydropulping process, this is a very promising option for Tetra Pak recycling. However, the procedure is not without drawbacks: firstly, because of the cost-effective energy consumption needed to separate the solvent-antisolvent mixture and secondly, due to its high environmental impact. The economic viability of this technique rests upon whether the solvent-antisolvent mixture can be separated cheaply (Figure 9) [33].
The SDP process. Image inspired by Georgiopoulou et al. [
This technique has been developed by researchers in China and focuses on the separation of LDPE and aluminum by means of a separation reagent, mostly aqueous solutions of organic acids or even mixtures of acids. The procedure works by breaking the mechanical bonds holding the laminate together and as such allows for recovery of the products.
The yield of the process is highly dependent on the conditions of the reaction. In the process some of the aluminum is dissolved by the acid—which is also consumed—and thus losses are to be expected. However, this depends on many factors such as acid used, temperature, etc. Product purity is also correlated with those factors.
After trial and error, it has been found that methanoic acid is the best separation reagent for Tetra Pak. Lastly, there seems to be a high correlation between the separation rate, the temperature the reaction is taking place at, and the concentration of the reagent. More specifically, reaction time decreases with the rise of reagent concentration and temperature (Figure 10) [37].
The acid-based delamination process. Image inspired by Zhang Ji-fei et al. [
Thanks to the high heating value of the Al-LDPE laminate (40 MJ/Kg), it can be used as a sufficient fuel source. This has taken precedent especially in Europe. Although the laminate can be used directly after the hydropulping process, it is most usually used in conjunction with other fuel sources. This recycling route can be considered environmentally friendly as the LDPE of Tetra Pak burns cleanly without producing fumes containing elements such as sulfur, nitrogen, or halogens.
Also, the Al2O3 produced during pyrolysis, by the reaction between Al and moisture in high heat conditions, is in big part exploited by the cement industry, which uses it as a desired component of cement production [36]. Lastly there is the choice of forming finished products directly by using the laminates in roof tile production, injection and rotational molding, and PE-Al agglomeration and pulverization [42, 43].
In these times that society demands a more environmental way of thinking from the industry, recycling of multilayer packaging becomes a priority for many scientists. They have developed a plethora of ways to recycle such packaging, from using it as a fuel to using its pyrolysis products as a mercury absorbent. It is most likely that this field will keep on expanding with ever more innovative and cost-effective ways to fully exploit, reuse, and transform the Tetra Pak multilayer packaging as human development is going into the future.
The rapid technological advances along with people’s need for better living conditions resulted in a global rise in the consumption of EEE over the last years and so in huge amounts of WEEE [44]. Plastics in WEEE account for ~30% of WEEE and in most cases contain BFR that necessitates careful handling [9], since BFR’s presence in plastics leads to the formation of various, toxic brominated substances in the liquid fraction obtained after pyrolysis, inhibiting its further use. In such cases a pretreatment step before or during the recycling is necessary in order to receive bromine-free products. So, due to the fact that
One very common pretreatment method for the removal of BFR applied before pyrolysis is
Apart from the typical soxhlet extraction, many advanced solvent extraction techniques have been explored over the years, including supercritical fluid extraction (SFE), pressurized liquid extraction (PLE), ultrasonic-assisted extraction (UAE), and microwave-assisted extraction (MAE). These techniques require less time and volumes of solvents than those during soxhlet extraction [47]. Vilaplana et al. applied MAE for the removal of TBBPA and decabromodiphenyl ether (Deca-BDE) from virgin high-impact polystyrene (HIPS) and standard samples from real WEEE. They found that complete extraction of TBBPA took place when they used a combination of polar/nonpolar solvent system (isopropanol/n-hexane) and high extraction temperatures (130°C). On the other hand, in case of Deca-BDE, there were obtained lower extraction yields due to its high molecular weight and its nonpolar nature [47].
In another study [48], UAE and MAE were investigated for the recovery of TBBPA from real WEEE samples that consisted of ABS, polypropylene (PP), polycarbonate (PC), and blends of ABS/PC. From the results obtained it was proved that MAE was more efficient in extracting TBBPA than UAE, especially in case of ABS polymers. The optimal solvent media was isopropanol: n-hexane (1:1), which is a binary mixture of a polar –nonpolar solvent, whereas pure isopropanol, as a solvent, could not result in complete extraction of TBBPA [48].
As mentioned previously, SFE has also attracted a lot of attention as regards the degradation of brominated flame-retarded plastics from WEEE, because of the supercritical fluids’ unique properties, such as high density, low viscosity, varied permittivity related to pressure, and high mass transfer, as well as the fact that their viscosity, density, and diffusion coefficient are very sensitive to changes in temperature and pressure. Supercritical fluids appear at temperature and pressure higher than their critical state. Supercritical CO2 is the most widely used fluid in SFE, since it presents remarkable advantages, including: low critical point, low cost, ease of availability, non-toxicity, recyclability, and simplicity as regards its operation. Water is also, a cheap, nontoxic, and easily available fluid, but it has a relatively high supercritical point [49].
Onwudili and Williams [50] studied supercritical water (T > 374°C and P > 22.1 MPa) due to the fact that it presents different characteristics in comparison with organic solvents. They focused on ABS and HIPS, since they are some of the most representative brominated plastics in WEEE and degraded them in supercritical water (up to 450°C and 31 MPa) in a batch reactor. Furthermore, they investigated the effect of alkaline additives, NaOH and Ca(OH)2, by treating the plastics both in the absence and in the presence of them. They noticed that oils, which were the main reaction products, had almost zero bromine and antimony content in the presence of NaOH additive [50]. In another work, [51] there was used subcritical water for the debromination of printed circuit boards (PCB) that contained BFR in a high-pressure batch reactor. They applied three different temperatures, 225, 250, and 275°C, and noticed that debromination increased with increase in temperature. After the debromination of the samples, they applied recycling methods, such as pyrolysis.
Apart from water, organic solvents such as acetone, methanol, and ethanol can also be used as supercritical fluids in chemical recycling of plastics from WEEE [52]. For instance, Wang and Zhang [52] used various supercritical fluids: acetone, methanol, isopropanol, and water with a view to studying the degradation of waste computer housing plastics that contained BFR. They came to the conclusion that supercritical fluid process was efficient for the debromination and decomposition of brominated flame-retarded plastics enabling the recycling of bromine-free oil. As for solvent’s efficiency in debromination, the order was the following: water > methanol > isopropanol > acetone.
It should be highlighted here that although SFE technology is considered as a green choice for resource recovery, it has some important drawbacks as well. One of the main obstacles in such technology is the fact that only equipment able to withstand high pressures and temperatures and very resistant to corrosion can be used. These demands, however, increase the cost a lot, and along with the large amount of energy that is required, prevent its industrial implementation [49].
To avoid the latter difficulties, there are other approaches that can be applied in case of flame-retarded plastics. One such approach is that of
As described above, during co-pyrolysis, the end-of-life brominated plastics along with other (plastic) waste are pyrolyzed together and result in bromine reduction in the derived pyrolysis oil, without any kind of pretreatment before the pyrolysis process. Another idea, in order to reduce bromine while avoiding the extra pretreatment step, is that of the
During
In another study [59], there was investigated activated Al2O3 for catalytic pyrolysis of waste PCB examining three different temperatures: 400, 500, and 600°C, as well as different ratios of PCB: Al2O3. They noticed that higher temperatures improved the oil production; and the optimal results as regards the production of light oil and the debromination were obtained at 600°C. The catalyst’s presence increased the formation of light hydrocarbons and in the meantime the debromination. Wu et al. [60] carried out catalytic pyrolysis of brominated HIPS that also contained Sb2O3, in the presence of red mud, limestone, and natural zeolite, with a view to eliminating bromine and antimony from the pyrolysis oil. They found that in their presence, the total amount of bromine (and antimony) in the oil was reduced. Nevertheless, red mud was the most efficient catalyst in reducing bromine, since Fe2O3 present in red mud reacted with HBr that was formed during the degradation of the BFR and hindered the formation of the volatile SbBr3; in the meanwhile, its zeolite property catalytically destroyed the organobromine compounds [60].
Co-pyrolysis can also take place in the presence of catalysts, known as
An example that belongs in the first category is [63], in which they examined a small-scale two-stage pyrolysis and catalytic reforming of brominated flame-retarded HIPS at 500°C using four zeolites: natural zeolite (NZ), iron oxide–loaded natural zeolite (Fe-NZ), HY zeolite (YZ), and iron oxide–loaded HY zeolite (Fe-YZ). They observed that the bromine content in the oil was reduced in the presence of catalysts; however, Fe-NZ and Fe-YZ showed better debromination results, due to the reactions between the iron oxide that was loaded and the derived HBr. Compared with Fe-YZ, Fe-NZ did not greatly change the pyrolysis products and so preserved the valuable single-ring aromatic compounds. As a result, Fe-NZ was more effective and feasible for the feedstock recycling of brominated HIPS via the pyrolysis process.
Areeprasert and Khaobang [64] studied pyrolysis and catalytic reforming of a polymer blend (ABS/PC) and PCB, at 500°C, using some conventional catalysts: Y-zeolite (YZ), ZSM-5, iron oxide–loaded Y-zeolite (Fe/YZ), and iron oxide–loaded ZSM-5 (Fe/ZSM-5), as well as some alternative, green catalysts: biochar (BC), electronic waste char (EWC), iron oxide–loaded biochar (Fe/BC), and iron oxide–loaded electronic waste char (Fe/EWC). They found that all catalysts increased the single-ring hydrocarbon products of the liquid fraction. As for the debromination, it was noticed that in case of ABS/PC, the most effective catalyst was Fe/BC, whereas in case of PCB, it was Fe/EWC. Also, they concluded that the green-renewable catalysts could be a promising choice for removing bromine from the liquid fraction [64]. Ma et al. [65] investigated pyrolysis-catalytic upgrading of brominated flame-retarded ABS. The process took place in a two-stage fixed bed reactor; and the second stage included the catalytic upgrading of the vapor intermediates that were obtained from pyrolysis (first stage). The examined catalysts were: HZSM-5 and Fe/ZSM-5. Both catalysts had high catalytic cracking activities that led to an increased yield of oil and to a reduction of the bromine in the liquid fraction.
This chapter briefly presents all methods that are used nowadays for plastic recycling, including primary recycling, energy recovery, mechanical recycling, and chemical recycling. The advantages and disadvantages of each method are discussed. Emphasis though is given on chemical recycling and mainly, pyrolysis, due to its many benefits, which are fully described. Furthermore, three case studies that involve some difficulties in plastic recycling are thoroughly investigated. The first one includes the case of polymeric blends, where the coexistence of different plastic materials makes their recycling more difficult. The second one is focused on the recycling of plastics that come from multilayer packaging. The main obstacle in this case lies in the fact that multilayer packaging comprises various, different materials, such as paper and metals, apart from the plastics, so extra attention is required for their separation and recycling. The last case study that is presented here is that of brominated flame-retarded plastics from WEEE, since in such cases direct recycling is not that easy due to the formation of undesirable brominated compounds and more often than not a pretreatment step prior to their recycling is necessary. Taking into account the mentioned difficulties, the aim of this chapter is to present and analyze various recent literature data along with suggestions on how to overcome the mentioned problems.
The research work was supported by the Hellenic Foundation for Research and Innovation (HFRI) under the HFRI PhD Fellowship grant (Fellowship Number: 853).
IntechOpen implements a robust policy to minimize and deal with instances of fraud or misconduct. As part of our general commitment to transparency and openness, and in order to maintain high scientific standards, we have a well-defined editorial policy regarding Retractions and Corrections.
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\\n\\nA Statement of Concern detailing alleged misconduct will be issued by the Academic Editor or publisher following a 3rd party report of scientific misconduct when:
\\n\\nIntechOpen believes that the number of occasions on which a Statement of Concern is issued will be very few in number. In all cases when such a decision has been taken by the Academic Editor the decision will be reviewed by another editor to whom the author can make representations.
\\n\\n3. CORRECTIONS
\\n\\nA Correction will be issued by the Academic Editor when:
\\n\\n3.1. ERRATUM
\\n\\nAn Erratum will be issued by the Academic Editor when it is determined that a mistake in a Chapter originates from the production process handled by the publisher.
\\n\\nA published Erratum will adhere to the Retraction Notice publishing guidelines outlined above.
\\n\\n3.2. CORRIGENDUM
\\n\\nA Corrigendum will be issued by the Academic Editor when it is determined that a mistake in a Chapter is a result of an Author’s miscalculation or oversight. A published Corrigendum will adhere to the Retraction Notice publishing guidelines outlined above.
\\n\\n4. FINAL REMARKS
\\n\\nIntechOpen wishes to emphasize that the final decision on whether a Retraction, Statement of Concern, or a Correction will be issued rests with the Academic Editor. The publisher is obliged to act upon any reports of scientific misconduct in its publications and to make a reasonable effort to facilitate any subsequent investigation of such claims.
\\n\\nIn the case of Retraction or removal of the Work, the publisher will be under no obligation to refund the APC.
\\n\\nThe general principles set out above apply to Retractions and Corrections issued in all IntechOpen publications.
\\n\\nAny suggestions or comments on this Policy are welcome and may be sent to permissions@intechopen.com.
\\n\\nPolicy last updated: 2017-09-11
\\n"}]'},components:[{type:"htmlEditorComponent",content:'IntechOpen’s Retraction and Correction Policy has been developed in accordance with the Committee on Publication Ethics (COPE) publication guidelines relating to scientific misconduct and research ethics:
\n\n1. RETRACTIONS
\n\nA Retraction of a Chapter will be issued by the Academic Editor, either following an Author’s request to do so or when there is a 3rd party report of scientific misconduct. Upon receipt of a report by a 3rd party, the Academic Editor will investigate any allegations of scientific misconduct, working in cooperation with the Author(s) and their institution(s).
\n\nA formal Retraction will be issued when there is clear and conclusive evidence of any of the following:
\n\nPublishing of a Retraction Notice will adhere to the following guidelines:
\n\n1.2. REMOVALS AND CANCELLATIONS
\n\n2. STATEMENTS OF CONCERN
\n\nA Statement of Concern detailing alleged misconduct will be issued by the Academic Editor or publisher following a 3rd party report of scientific misconduct when:
\n\nIntechOpen believes that the number of occasions on which a Statement of Concern is issued will be very few in number. In all cases when such a decision has been taken by the Academic Editor the decision will be reviewed by another editor to whom the author can make representations.
\n\n3. CORRECTIONS
\n\nA Correction will be issued by the Academic Editor when:
\n\n3.1. ERRATUM
\n\nAn Erratum will be issued by the Academic Editor when it is determined that a mistake in a Chapter originates from the production process handled by the publisher.
\n\nA published Erratum will adhere to the Retraction Notice publishing guidelines outlined above.
\n\n3.2. CORRIGENDUM
\n\nA Corrigendum will be issued by the Academic Editor when it is determined that a mistake in a Chapter is a result of an Author’s miscalculation or oversight. A published Corrigendum will adhere to the Retraction Notice publishing guidelines outlined above.
\n\n4. FINAL REMARKS
\n\nIntechOpen wishes to emphasize that the final decision on whether a Retraction, Statement of Concern, or a Correction will be issued rests with the Academic Editor. The publisher is obliged to act upon any reports of scientific misconduct in its publications and to make a reasonable effort to facilitate any subsequent investigation of such claims.
\n\nIn the case of Retraction or removal of the Work, the publisher will be under no obligation to refund the APC.
\n\nThe general principles set out above apply to Retractions and Corrections issued in all IntechOpen publications.
\n\nAny suggestions or comments on this Policy are welcome and may be sent to permissions@intechopen.com.
\n\nPolicy last updated: 2017-09-11
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His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. 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Samim Al Azad and Slimane Ed-dafali",coverURL:"https://cdn.intechopen.com/books/images_new/11392.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"418514",title:"Dr.",name:"Muhammad",middleName:null,surname:"Mohiuddin",slug:"muhammad-mohiuddin",fullName:"Muhammad Mohiuddin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10400",title:"The Application of Ant Colony Optimization",subtitle:null,isOpenForSubmission:!1,hash:"f4fdfd07ee1ab99fb7c740d6d0c144c6",slug:"the-application-of-ant-colony-optimization",bookSignature:"Ali Soofastaei",coverURL:"https://cdn.intechopen.com/books/images_new/10400.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"257455",title:"Dr.",name:"Ali",middleName:null,surname:"Soofastaei",slug:"ali-soofastaei",fullName:"Ali Soofastaei"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10915",title:"Leadership",subtitle:"New Insights",isOpenForSubmission:!1,hash:"0d72e79892f2a020cee66a52d09de5a4",slug:"leadership-new-insights",bookSignature:"Mário Franco",coverURL:"https://cdn.intechopen.com/books/images_new/10915.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"105529",title:"Dr.",name:"Mário",middleName:null,surname:"Franco",slug:"mario-franco",fullName:"Mário Franco"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10683",title:"Technological Innovations and Advances in Hydropower Engineering",subtitle:null,isOpenForSubmission:!1,hash:"7ce7ad8768bd2cad155470fe1fd883f4",slug:"technological-innovations-and-advances-in-hydropower-engineering",bookSignature:"Yizi Shang, Ling Shang and Xiaofei Li",coverURL:"https://cdn.intechopen.com/books/images_new/10683.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"349630",title:"Dr.",name:"Yizi",middleName:null,surname:"Shang",slug:"yizi-shang",fullName:"Yizi Shang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7102",title:"Pneumonia",subtitle:null,isOpenForSubmission:!1,hash:"9fd70142814192dcec58a176749f1b60",slug:"pneumonia",bookSignature:"Nima Rezaei",coverURL:"https://cdn.intechopen.com/books/images_new/7102.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9670",title:"Current Trends in Wheat Research",subtitle:null,isOpenForSubmission:!1,hash:"89d795987f1747a76eee532700d2093d",slug:"current-trends-in-wheat-research",bookSignature:"Mahmood-ur-Rahman Ansari",coverURL:"https://cdn.intechopen.com/books/images_new/9670.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"185476",title:"Dr.",name:"Mahmood-ur-Rahman",middleName:null,surname:"Ansari",slug:"mahmood-ur-rahman-ansari",fullName:"Mahmood-ur-Rahman Ansari"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"62",title:"Accounting",slug:"accounting",parent:{id:"7",title:"Business, Management and Economics",slug:"business-management-and-economics"},numberOfBooks:3,numberOfSeries:0,numberOfAuthorsAndEditors:70,numberOfWosCitations:8,numberOfCrossrefCitations:28,numberOfDimensionsCitations:40,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"62",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"10818",title:"Accounting and Finance Innovations",subtitle:null,isOpenForSubmission:!1,hash:"dd81bc60e806fddc63d1ae22da1c779a",slug:"accounting-and-finance-innovations",bookSignature:"Nizar M. Alsharari",coverURL:"https://cdn.intechopen.com/books/images_new/10818.jpg",editedByType:"Edited by",editors:[{id:"231461",title:"Dr.",name:"Nizar",middleName:"Mohammad",surname:"Alsharari",slug:"nizar-alsharari",fullName:"Nizar Alsharari"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6660",title:"Accounting from a Cross-Cultural Perspective",subtitle:null,isOpenForSubmission:!1,hash:"1fbbfae523cabcfa248b56822a2221cc",slug:"accounting-from-a-cross-cultural-perspective",bookSignature:"Asma Salman and Muthanna G. Abdul Razzaq",coverURL:"https://cdn.intechopen.com/books/images_new/6660.jpg",editedByType:"Edited by",editors:[{id:"206443",title:"Prof.",name:"Asma",middleName:null,surname:"Salman",slug:"asma-salman",fullName:"Asma Salman"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6000",title:"Accounting and Corporate Reporting",subtitle:"Today and Tomorrow",isOpenForSubmission:!1,hash:"aa4f840bdfa861be2f1c4b982a1e2cb5",slug:"accounting-and-corporate-reporting-today-and-tomorrow",bookSignature:"Soner Gokten",coverURL:"https://cdn.intechopen.com/books/images_new/6000.jpg",editedByType:"Edited by",editors:[{id:"70354",title:"Ph.D.",name:"Soner",middleName:null,surname:"Gokten",slug:"soner-gokten",fullName:"Soner Gokten"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:3,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"55533",doi:"10.5772/intechopen.69264",title:"The Future of Accounting Profession in an Era of Start-Ups",slug:"the-future-of-accounting-profession-in-an-era-of-start-ups",totalDownloads:2035,totalCrossrefCites:6,totalDimensionsCites:8,abstract:"With the help of the advancements in the field of communication and information technologies, the number of IT-based software has rapidly increased and the capabilities of high-budget enterprise resource planning (ERP) software widely used by large enterprises have begun to be offered to small and medium-sized enterprises (SMEs). In this chapter, cloud computing and other information technologies based accounting start-ups are covered, and the effects of these highly increasing start-ups on the profession of accounting have been addressed. In conclusion, it has been predicted that technology-based accounting start-ups with both accounting professionals and entrepreneurs having an expertise on information technologies will come together and will increase in the future, and cloud-based accounting initiatives will shape the future of the profession.",book:{id:"6000",slug:"accounting-and-corporate-reporting-today-and-tomorrow",title:"Accounting and Corporate Reporting",fullTitle:"Accounting and Corporate Reporting - Today and Tomorrow"},signatures:"Burak Özdoğan",authors:[{id:"203445",title:"Dr.",name:"Burak",middleName:null,surname:"Ozdogan",slug:"burak-ozdogan",fullName:"Burak Ozdogan"}]},{id:"55274",doi:"10.5772/intechopen.68832",title:"Paradigm Shift in Corporate Reporting",slug:"paradigm-shift-in-corporate-reporting",totalDownloads:2189,totalCrossrefCites:4,totalDimensionsCites:6,abstract:"In this paper, we present the evolution of integrated reporting and organizations playing an active role in this process. As a result of the changes, corporate reports including only historical financial information have become insufficient. It has started to be important for the firms to be sensitive towards environment, social capital and governance. For these reasons, authorities started to search for new reporting types. Their aim was to form a report giving detailed (prospective and retrospective) information about the total performance of the firm. Sustainability reports, the starting point of integrated reporting, were established and Global Reporting Initiative (GRI) standards were formed to increase the popularization. Integrated reports aim to supply full disclosure about the firms’ strategies, goals and performances. They also respond to the demands and needs of key stakeholders. In order to actualize the financial stability and sustainability, they are necessary. Integrated reports also put related groups into play. So, decision makers become a participant instead of watching the system from outside. In addition, integrated thinking philosophy provides systematic disclosure of value creation, namely how organizations made resource allocations in the past and how they will create value in the future according to their business models.",book:{id:"6000",slug:"accounting-and-corporate-reporting-today-and-tomorrow",title:"Accounting and Corporate Reporting",fullTitle:"Accounting and Corporate Reporting - Today and Tomorrow"},signatures:"Pınar Okan Gökten and Beyhan Marşap",authors:[{id:"204188",title:"Ph.D.",name:"Pınar",middleName:null,surname:"Okan Gokten",slug:"pinar-okan-gokten",fullName:"Pınar Okan Gokten"},{id:"204189",title:"Prof.",name:"Beyhan",middleName:null,surname:"Marsap",slug:"beyhan-marsap",fullName:"Beyhan Marsap"}]},{id:"56092",doi:"10.5772/intechopen.69103",title:"Value Relevance of Accounting Data in an Emerging Market: Did Accounting Reforms Make a Difference?",slug:"value-relevance-of-accounting-data-in-an-emerging-market-did-accounting-reforms-make-a-difference-",totalDownloads:1450,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"This study investigates the association of accounting earnings (NI) and book value of equity (BV) with stock prices in Istanbul Stock Exchange (ISE), currently Borsa Istanbul (BIST), during the 1992–2006 period. We also explore the effect of accounting reforms on value relevance that is measured as the strength of the association between a firm’s NI and BV and its market value. We specifically investigate the impact of the Turkish Uniform Chart of Accounts (1994), mandatory inflation accounting, consolidations and voluntary (2003–2004), and the mandatory (2005) adoption of International Financial Reporting Standards (IFRS). We hypothesize that these reforms have reduced information asymmetry and thus are expected to enhance the value relevance of accounting information. We find strong evidence that the Ohlson model is a valid model, and BV is more value relevant than NI in BIST. We also find that inflation accounting and consolidations have enhanced the value relevance of BV, while IFRS has increased the value relevance of NI, but reduced that of BV. We contribute to the debate by exploiting the unique sequence of reforms, to come up with comparative value relevance testing designs and interesting results for all major reforms, which we believe will be instructive for researchers and for all emerging and developed economies undergoing similar reforms and best practices.",book:{id:"6000",slug:"accounting-and-corporate-reporting-today-and-tomorrow",title:"Accounting and Corporate Reporting",fullTitle:"Accounting and Corporate Reporting - Today and Tomorrow"},signatures:"Mine Aksu, Ayse Tansel Cetin and Can Simga Mugan",authors:[{id:"203574",title:"Associate Prof.",name:"Mine",middleName:null,surname:"Aksu",slug:"mine-aksu",fullName:"Mine Aksu"},{id:"204249",title:"Prof.",name:"Can Simga",middleName:null,surname:"Mugan",slug:"can-simga-mugan",fullName:"Can Simga Mugan"},{id:"204250",title:"Prof.",name:"Ayse",middleName:null,surname:"Tansel Cetin",slug:"ayse-tansel-cetin",fullName:"Ayse Tansel Cetin"}]},{id:"61095",doi:"10.5772/intechopen.76867",title:"Ethical Awareness, Ethical Decision Making, and Transparency: A Study on Turkish CPAs in Istanbul",slug:"ethical-awareness-ethical-decision-making-and-transparency-a-study-on-turkish-cpas-in-istanbul",totalDownloads:1619,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"This research aims to reveal the connections among ethical awareness, ethical decision making, and transparency from the perspective of certified public accountants (CPAs) in Istanbul. Data are collected from Turkish CPAs’ survey responses, which are based on a seven-point Likert scale, and analyzed using explanatory factor analysis. Hypotheses were tested using ordinary least squares regression, and the results show that, based on the participants’ average responses, CPAs are affected mainly by the level of their ethical awareness in decision making about an ethical issue or transparency of financial reports, which indicates that the three concepts are strongly connected to each other.",book:{id:"6660",slug:"accounting-from-a-cross-cultural-perspective",title:"Accounting from a Cross-Cultural Perspective",fullTitle:"Accounting from a Cross-Cultural Perspective"},signatures:"Nida Türegün",authors:[{id:"238085",title:"Ph.D.",name:"Nida",middleName:null,surname:"Türegün",slug:"nida-turegun",fullName:"Nida Türegün"}]},{id:"55385",doi:"10.5772/intechopen.68778",title:"Public Accounting Reform from Institutional Theory Perspectives: Case of Turkey",slug:"public-accounting-reform-from-institutional-theory-perspectives-case-of-turkey",totalDownloads:1711,totalCrossrefCites:0,totalDimensionsCites:2,abstract:"In the literature, it is often found that institutional theory is used as the theoretical framework to explain the development and application of accounting. By means of these studies, it becomes easier to understand accounting as a social and political activity within itself and thus to be able to understand the economic, institutional, political and social environment of the turnover of the practices. In this regard, the main aim of this study is to explain the development of the public accounting system in Turkey with the help of institutional theory. Thus, it is aimed to explain all the dynamics that provide the institutionalization of state account in the national sense, together with the economic, political and social processes of the period in question. It is revealed that the regulatory arrangements directly contribute to the institutionalization of a field, and as a result, how the public organizations directly contribute to the institutionalization process.",book:{id:"6000",slug:"accounting-and-corporate-reporting-today-and-tomorrow",title:"Accounting and Corporate Reporting",fullTitle:"Accounting and Corporate Reporting - Today and Tomorrow"},signatures:"Ceray Aldemir and Tuğba Uçma Uysal",authors:[{id:"204342",title:"Dr.",name:"Ceray",middleName:null,surname:"Aldemir",slug:"ceray-aldemir",fullName:"Ceray Aldemir"},{id:"204348",title:"Dr.",name:"Tugba",middleName:null,surname:"Ucma Uysal",slug:"tugba-ucma-uysal",fullName:"Tugba Ucma Uysal"}]}],mostDownloadedChaptersLast30Days:[{id:"78825",title:"Accounting Quality and Its Challenges in 21st Century",slug:"accounting-quality-and-its-challenges-in-21st-century",totalDownloads:256,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"This paper describes current research to drive future research challenges in accounting quality. The definition of accounting quality is mainly varying depending on the objective that the study pointed. Previous research revealed that many proxies describe the accounting quality but most of them from the financial perspective. Furthermore, this paper tries to expose this research issue in the behavioural approach and drive future research in the mixed method. It concludes that the behavioural issues can be a research model, triggering future research challenges in accounting quality. The authors support these triggers from the perspectives of political hegemony, bureaucracy ratcheting, cognitive distortion, and international accounting standard. Finally, we infer and simultaneously predict that accounting quality would broaden its concepts and lasting impression in the 21st century.",book:{id:"10818",slug:"accounting-and-finance-innovations",title:"Accounting and Finance Innovations",fullTitle:"Accounting and Finance Innovations"},signatures:"Sumiyana Sumiyana, Hendrian Hendrian, Ruslan Effendi, Krisnhoe Fitrijati and Sriwidharmanely Sriwidharmanely",authors:[{id:"328451",title:"Prof.",name:"Sumiyana",middleName:null,surname:"Sumiyana",slug:"sumiyana-sumiyana",fullName:"Sumiyana Sumiyana"},{id:"328452",title:"Dr.",name:"Sriwidharmanely",middleName:null,surname:"Sriwidharmanely",slug:"sriwidharmanely-sriwidharmanely",fullName:"Sriwidharmanely Sriwidharmanely"},{id:"350499",title:"Dr.",name:"Hendrian",middleName:null,surname:"Hendrian",slug:"hendrian-hendrian",fullName:"Hendrian Hendrian"},{id:"350500",title:"Dr.",name:"Ruslan",middleName:null,surname:"Effendi",slug:"ruslan-effendi",fullName:"Ruslan Effendi"},{id:"350501",title:"Dr.",name:"Krisnhoe",middleName:null,surname:"Fitrijati",slug:"krisnhoe-fitrijati",fullName:"Krisnhoe Fitrijati"}]},{id:"61095",title:"Ethical Awareness, Ethical Decision Making, and Transparency: A Study on Turkish CPAs in Istanbul",slug:"ethical-awareness-ethical-decision-making-and-transparency-a-study-on-turkish-cpas-in-istanbul",totalDownloads:1619,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"This research aims to reveal the connections among ethical awareness, ethical decision making, and transparency from the perspective of certified public accountants (CPAs) in Istanbul. Data are collected from Turkish CPAs’ survey responses, which are based on a seven-point Likert scale, and analyzed using explanatory factor analysis. Hypotheses were tested using ordinary least squares regression, and the results show that, based on the participants’ average responses, CPAs are affected mainly by the level of their ethical awareness in decision making about an ethical issue or transparency of financial reports, which indicates that the three concepts are strongly connected to each other.",book:{id:"6660",slug:"accounting-from-a-cross-cultural-perspective",title:"Accounting from a Cross-Cultural Perspective",fullTitle:"Accounting from a Cross-Cultural Perspective"},signatures:"Nida Türegün",authors:[{id:"238085",title:"Ph.D.",name:"Nida",middleName:null,surname:"Türegün",slug:"nida-turegun",fullName:"Nida Türegün"}]},{id:"78745",title:"Analysis of Return and Risk of Cryptocurrency Bitcoin Asset as Investment Instrument",slug:"analysis-of-return-and-risk-of-cryptocurrency-bitcoin-asset-as-investment-instrument",totalDownloads:421,totalCrossrefCites:1,totalDimensionsCites:0,abstract:"This study aims to explore the potential use of the cryptocurrency bitcoin as an investment instrument in Indonesia. The return obtained from bitcoin cryptocurrency is compared to other investment instruments, namely stock returns, gold and the rupiah exchange rate. The research period was carried out based on research data from 2011 to 2020. This study employee compares means test (t test) and analysis of variance (F test) on rate of return of bitcoin investment. The bitcoin return compare to the rate of return form the others investments instruments namely exchange rate, gold and stock. The study collected 120 data of each investments instruments: bitcoin, exchange rate, gold and stock from various of sources during 2011–2020. Then, we calculate the return and risk of individual investment instruments. The results showed that the bitcoin currency had the highest rate of return 18% with a standard deviation of 61% compared to exchange rate, gold and stock returns. While the rate of return for the others investment instruments showed less than 0.5% with standard deviation less than 5%. The rate of return bitcoin has significance difference compare to the rate of return of exchange rate, gold and stock. The study contribute for the investors who would like to invest on bitcoin. The investors should understand the characteristic of bitcoin in term of rate of returns and also the risk. This study also contributes to government of Indonesia on crypto currency development. The Indonesia government should adopt and regulate on crypto currency in the future to secure the investor and economic growth.",book:{id:"10818",slug:"accounting-and-finance-innovations",title:"Accounting and Finance Innovations",fullTitle:"Accounting and Finance Innovations"},signatures:"Sunita Dasman",authors:[{id:"348739",title:"Dr.",name:"Sunita",middleName:null,surname:"Dasman",slug:"sunita-dasman",fullName:"Sunita Dasman"}]},{id:"55587",title:"Historical Development of Government Accounting",slug:"historical-development-of-government-accounting",totalDownloads:2774,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Government accounting aims at preventing waste in government services and establishing a balance between optimal expenditure and services by managing government assets and government sources in the most efficient way. This balance can be established only by obtaining complete and accurate information from government accounting system on time. Since the users have a low level of knowledge needs in government accounting system, it has been recorded for long years in a cash basis manner. However, as the government’s area of operation expanded and the needs increased, it became obvious that cash basis system had lacking parts. So it started to focus on recording financial transactions and financial reporting. These lacking parts in the accounting system tried to be overcome through a new regulation by focusing on the areas where cash basis accounting system was insufficient; and a change was experienced with regard to applying the accrual basis in the areas of government accounting and financial reporting. This study aims to explain the historical development of government accounting by applications in countries and especially by detailed expressions for Turkey. As a result of the literature review and the examination of countries’ government accounting practices, it has been determined that the government accounting practice has made the correct transition from cash basis to accrual basis.",book:{id:"6000",slug:"accounting-and-corporate-reporting-today-and-tomorrow",title:"Accounting and Corporate Reporting",fullTitle:"Accounting and Corporate Reporting - Today and Tomorrow"},signatures:"Mihriban Coşkun Arslan",authors:[{id:"203724",title:"Dr.",name:"Mihriban",middleName:null,surname:"Coşkun Arslan",slug:"mihriban-coskun-arslan",fullName:"Mihriban Coşkun Arslan"}]},{id:"55289",title:"Behavioral Accounting and its Interactions",slug:"behavioral-accounting-and-its-interactions",totalDownloads:4019,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Behavioral accounting is a branch of accounting that is related to behavior besides the accounting knowledge. It deals with the attitude and behavior of people when they are encountered with an accounting phenomenon which determines the behavior that they will show in decision‐making. This special area of accounting addresses such aspects as human information‐processing behavior, judgment quality, accounting problems that are created by users and providers of accounting information, and accounting information users’ and producers’ decision‐making skills. Behavioral research tries to find out how individuals make decisions and interact and influence other individuals, organizations, markets, and society. 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His research interest focuses on computational chemistry and molecular modeling of diverse systems of pharmacological, food, and alternative energy interests by resorting to DFT and Conceptual DFT. He has authored a coauthored more than 255 peer-reviewed papers, 32 book chapters, and 2 edited books. He has delivered speeches at many international and domestic conferences. He serves as a reviewer for more than eighty international journals, books, and research proposals as well as an editor for special issues of renowned scientific journals.",institutionString:"Centro de Investigación en Materiales Avanzados",institution:{name:"Centro de Investigación en Materiales Avanzados",country:{name:"Mexico"}}},{id:"76477",title:"Prof.",name:"Mirza",middleName:null,surname:"Hasanuzzaman",slug:"mirza-hasanuzzaman",fullName:"Mirza Hasanuzzaman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/76477/images/system/76477.png",biography:"Dr. Mirza Hasanuzzaman is a Professor of Agronomy at Sher-e-Bangla Agricultural University, Bangladesh. He received his Ph.D. in Plant Stress Physiology and Antioxidant Metabolism from Ehime University, Japan, with a scholarship from the Japanese Government (MEXT). Later, he completed his postdoctoral research at the Center of Molecular Biosciences, University of the Ryukyus, Japan, as a recipient of the Japan Society for the Promotion of Science (JSPS) postdoctoral fellowship. He was also the recipient of the Australian Government Endeavour Research Fellowship for postdoctoral research as an adjunct senior researcher at the University of Tasmania, Australia. Dr. Hasanuzzaman’s current work is focused on the physiological and molecular mechanisms of environmental stress tolerance. Dr. Hasanuzzaman has published more than 150 articles in peer-reviewed journals. He has edited ten books and written more than forty book chapters on important aspects of plant physiology, plant stress tolerance, and crop production. According to Scopus, Dr. Hasanuzzaman’s publications have received more than 10,500 citations with an h-index of 53. He has been named a Highly Cited Researcher by Clarivate. He is an editor and reviewer for more than fifty peer-reviewed international journals and was a recipient of the “Publons Peer Review Award” in 2017, 2018, and 2019. He has been honored by different authorities for his outstanding performance in various fields like research and education, and he has received the World Academy of Science Young Scientist Award (2014) and the University Grants Commission (UGC) Award 2018. He is a fellow of the Bangladesh Academy of Sciences (BAS) and the Royal Society of Biology.",institutionString:"Sher-e-Bangla Agricultural University",institution:{name:"Sher-e-Bangla Agricultural University",country:{name:"Bangladesh"}}},{id:"187859",title:"Prof.",name:"Kusal",middleName:"K.",surname:"Das",slug:"kusal-das",fullName:"Kusal Das",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBDeQAO/Profile_Picture_1623411145568",biography:"Kusal K. Das is a Distinguished Chair Professor of Physiology, Shri B. M. Patil Medical College and Director, Centre for Advanced Medical Research (CAMR), BLDE (Deemed to be University), Vijayapur, Karnataka, India. Dr. Das did his M.S. and Ph.D. in Human Physiology from the University of Calcutta, Kolkata. His area of research is focused on understanding of molecular mechanisms of heavy metal activated low oxygen sensing pathways in vascular pathophysiology. He has invented a new method of estimation of serum vitamin E. His expertise in critical experimental protocols on vascular functions in experimental animals was well documented by his quality of publications. He was a Visiting Professor of Medicine at University of Leeds, United Kingdom (2014-2016) and Tulane University, New Orleans, USA (2017). For his immense contribution in medical research Ministry of Science and Technology, Government of India conferred him 'G.P. Chatterjee Memorial Research Prize-2019” and he is also the recipient of 'Dr.Raja Ramanna State Scientist Award 2015” by Government of Karnataka. He is a Fellow of the Royal Society of Biology (FRSB), London and Honorary Fellow of Karnataka Science and Technology Academy, Department of Science and Technology, Government of Karnataka.",institutionString:"BLDE (Deemed to be University), India",institution:null},{id:"243660",title:"Dr.",name:"Mallanagouda Shivanagouda",middleName:null,surname:"Biradar",slug:"mallanagouda-shivanagouda-biradar",fullName:"Mallanagouda Shivanagouda Biradar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243660/images/system/243660.jpeg",biography:"M. S. Biradar is Vice Chancellor and Professor of Medicine of\nBLDE (Deemed to be University), Vijayapura, Karnataka, India.\nHe obtained his MD with a gold medal in General Medicine and\nhas devoted himself to medical teaching, research, and administrations. He has also immensely contributed to medical research\non vascular medicine, which is reflected by his numerous publications including books and book chapters. Professor Biradar was\nalso Visiting Professor at Tulane University School of Medicine, New Orleans, USA.",institutionString:"BLDE (Deemed to be University)",institution:{name:"BLDE University",country:{name:"India"}}},{id:"289796",title:"Dr.",name:"Swastika",middleName:null,surname:"Das",slug:"swastika-das",fullName:"Swastika Das",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/289796/images/system/289796.jpeg",biography:"Swastika N. Das is Professor of Chemistry at the V. P. Dr. P. G.\nHalakatti College of Engineering and Technology, BLDE (Deemed\nto be University), Vijayapura, Karnataka, India. She obtained an\nMSc, MPhil, and PhD in Chemistry from Sambalpur University,\nOdisha, India. Her areas of research interest are medicinal chemistry, chemical kinetics, and free radical chemistry. She is a member\nof the investigators who invented a new modified method of estimation of serum vitamin E. She has authored numerous publications including book\nchapters and is a mentor of doctoral curriculum at her university.",institutionString:"BLDEA’s V.P.Dr.P.G.Halakatti College of Engineering & Technology",institution:{name:"BLDE University",country:{name:"India"}}},{id:"248459",title:"Dr.",name:"Akikazu",middleName:null,surname:"Takada",slug:"akikazu-takada",fullName:"Akikazu Takada",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248459/images/system/248459.png",biography:"Akikazu Takada was born in Japan, 1935. After graduation from\nKeio University School of Medicine and finishing his post-graduate studies, he worked at Roswell Park Memorial Institute NY,\nUSA. He then took a professorship at Hamamatsu University\nSchool of Medicine. In thrombosis studies, he found the SK\npotentiator that enhances plasminogen activation by streptokinase. He is very much interested in simultaneous measurements\nof fatty acids, amino acids, and tryptophan degradation products. By using fatty\nacid analyses, he indicated that plasma levels of trans-fatty acids of old men were\nfar higher in the US than Japanese men. . He also showed that eicosapentaenoic acid\n(EPA) and docosahexaenoic acid (DHA) levels are higher, and arachidonic acid\nlevels are lower in Japanese than US people. By using simultaneous LC/MS analyses\nof plasma levels of tryptophan metabolites, he recently found that plasma levels of\nserotonin, kynurenine, or 5-HIAA were higher in patients of mono- and bipolar\ndepression, which are significantly different from observations reported before. In\nview of recent reports that plasma tryptophan metabolites are mainly produced by\nmicrobiota. He is now working on the relationships between microbiota and depression or autism.",institutionString:"Hamamatsu University School of Medicine",institution:{name:"Hamamatsu University School of Medicine",country:{name:"Japan"}}},{id:"137240",title:"Prof.",name:"Mohammed",middleName:null,surname:"Khalid",slug:"mohammed-khalid",fullName:"Mohammed Khalid",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/137240/images/system/137240.png",biography:"Mohammed Khalid received his B.S. degree in chemistry in 2000 and Ph.D. degree in physical chemistry in 2007 from the University of Khartoum, Sudan. He moved to School of Chemistry, Faculty of Science, University of Sydney, Australia in 2009 and joined Dr. Ron Clarke as a postdoctoral fellow where he worked on the interaction of ATP with the phosphoenzyme of the Na+/K+-ATPase and dual mechanisms of allosteric acceleration of the Na+/K+-ATPase by ATP; then he went back to Department of Chemistry, University of Khartoum as an assistant professor, and in 2014 he was promoted as an associate professor. In 2011, he joined the staff of Department of Chemistry at Taif University, Saudi Arabia, where he is currently an assistant professor. His research interests include the following: P-Type ATPase enzyme kinetics and mechanisms, kinetics and mechanisms of redox reactions, autocatalytic reactions, computational enzyme kinetics, allosteric acceleration of P-type ATPases by ATP, exploring of allosteric sites of ATPases, and interaction of ATP with ATPases located in cell membranes.",institutionString:"Taif University",institution:{name:"Taif University",country:{name:"Saudi Arabia"}}},{id:"63810",title:"Prof.",name:"Jorge",middleName:null,surname:"Morales-Montor",slug:"jorge-morales-montor",fullName:"Jorge Morales-Montor",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/63810/images/system/63810.png",biography:"Dr. Jorge Morales-Montor was recognized with the Lola and Igo Flisser PUIS Award for best graduate thesis at the national level in the field of parasitology. He received a fellowship from the Fogarty Foundation to perform postdoctoral research stay at the University of Georgia. He has 153 journal articles to his credit. He has also edited several books and published more than fifty-five book chapters. He is a member of the Mexican Academy of Sciences, Latin American Academy of Sciences, and the National Academy of Medicine. He has received more than thirty-five awards and has supervised numerous bachelor’s, master’s, and Ph.D. students. Dr. Morales-Montor is the past president of the Mexican Society of Parasitology.",institutionString:"National Autonomous University of Mexico",institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"217215",title:"Dr.",name:"Palash",middleName:null,surname:"Mandal",slug:"palash-mandal",fullName:"Palash Mandal",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/217215/images/system/217215.jpeg",biography:null,institutionString:"Charusat University",institution:null},{id:"49739",title:"Dr.",name:"Leszek",middleName:null,surname:"Szablewski",slug:"leszek-szablewski",fullName:"Leszek Szablewski",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49739/images/system/49739.jpg",biography:"Leszek Szablewski is a professor of medical sciences. He received his M.S. in the Faculty of Biology from the University of Warsaw and his PhD degree from the Institute of Experimental Biology Polish Academy of Sciences. He habilitated in the Medical University of Warsaw, and he obtained his degree of Professor from the President of Poland. Professor Szablewski is the Head of Chair and Department of General Biology and Parasitology, Medical University of Warsaw. Professor Szablewski has published over 80 peer-reviewed papers in journals such as Journal of Alzheimer’s Disease, Biochim. Biophys. Acta Reviews of Cancer, Biol. Chem., J. Biomed. Sci., and Diabetes/Metabol. Res. Rev, Endocrine. He is the author of two books and four book chapters. He has edited four books, written 15 scripts for students, is the ad hoc reviewer of over 30 peer-reviewed journals, and editorial member of peer-reviewed journals. Prof. Szablewski’s research focuses on cell physiology, genetics, and pathophysiology. He works on the damage caused by lack of glucose homeostasis and changes in the expression and/or function of glucose transporters due to various diseases. He has given lectures, seminars, and exercises for students at the Medical University.",institutionString:"Medical University of Warsaw",institution:{name:"Medical University of Warsaw",country:{name:"Poland"}}},{id:"173123",title:"Dr.",name:"Maitham",middleName:null,surname:"Khajah",slug:"maitham-khajah",fullName:"Maitham Khajah",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/173123/images/system/173123.jpeg",biography:"Dr. Maitham A. Khajah received his degree in Pharmacy from Faculty of Pharmacy, Kuwait University, in 2003 and obtained his PhD degree in December 2009 from the University of Calgary, Canada (Gastrointestinal Science and Immunology). Since January 2010 he has been assistant professor in Kuwait University, Faculty of Pharmacy, Department of Pharmacology and Therapeutics. His research interest are molecular targets for the treatment of inflammatory bowel disease (IBD) and the mechanisms responsible for immune cell chemotaxis. He cosupervised many students for the MSc Molecular Biology Program, College of Graduate Studies, Kuwait University. Ever since joining Kuwait University in 2010, he got various grants as PI and Co-I. He was awarded the Best Young Researcher Award by Kuwait University, Research Sector, for the Year 2013–2014. He was a member in the organizing committee for three conferences organized by Kuwait University, Faculty of Pharmacy, as cochair and a member in the scientific committee (the 3rd, 4th, and 5th Kuwait International Pharmacy Conference).",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"195136",title:"Dr.",name:"Aya",middleName:null,surname:"Adel",slug:"aya-adel",fullName:"Aya Adel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/195136/images/system/195136.jpg",biography:"Dr. Adel works as an Assistant Lecturer in the unit of Phoniatrics, Department of Otolaryngology, Ain Shams University in Cairo, Egypt. Dr. Adel is especially interested in joint attention and its impairment in autism spectrum disorder",institutionString:"Ain Shams University",institution:{name:"Ain Shams University",country:{name:"Egypt"}}},{id:"94911",title:"Dr.",name:"Boulenouar",middleName:null,surname:"Mesraoua",slug:"boulenouar-mesraoua",fullName:"Boulenouar Mesraoua",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94911/images/system/94911.png",biography:"Dr Boulenouar Mesraoua is the Associate Professor of Clinical Neurology at Weill Cornell Medical College-Qatar and a Consultant Neurologist at Hamad Medical Corporation at the Neuroscience Department; He graduated as a Medical Doctor from the University of Oran, Algeria; he then moved to Belgium, the City of Liege, for a Residency in Internal Medicine and Neurology at Liege University; after getting the Belgian Board of Neurology (with high marks), he went to the National Hospital for Nervous Diseases, Queen Square, London, United Kingdom for a fellowship in Clinical Neurophysiology, under Pr Willison ; Dr Mesraoua had also further training in Epilepsy and Continuous EEG Monitoring for two years (from 2001-2003) in the Neurophysiology department of Zurich University, Switzerland, under late Pr Hans Gregor Wieser ,an internationally known epileptologist expert. \n\nDr B. Mesraoua is the Director of the Neurology Fellowship Program at the Neurology Section and an active member of the newly created Comprehensive Epilepsy Program at Hamad General Hospital, Doha, Qatar; he is also Assistant Director of the Residency Program at the Qatar Medical School. \nDr B. Mesraoua's main interests are Epilepsy, Multiple Sclerosis, and Clinical Neurology; He is the Chairman and the Organizer of the well known Qatar Epilepsy Symposium, he is running yearly for the past 14 years and which is considered a landmark in the Gulf region; He has also started last year , together with other epileptologists from Qatar, the region and elsewhere, a yearly International Epilepsy School Course, which was attended by many neurologists from the Area.\n\nInternationally, Dr Mesraoua is an active and elected member of the Commission on Eastern Mediterranean Region (EMR ) , a regional branch of the International League Against Epilepsy (ILAE), where he represents the Middle East and North Africa(MENA ) and where he holds the position of chief of the Epilepsy Epidemiology Section; Dr Mesraoua is a member of the American Academy of Neurology, the Europeen Academy of Neurology and the American Epilepsy Society.\n\nDr Mesraoua's main objectives are to encourage frequent gathering of the epileptologists/neurologists from the MENA region and the rest of the world, promote Epilepsy Teaching in the MENA Region, and encourage multicenter studies involving neurologists and epileptologists in the MENA region, particularly epilepsy epidemiological studies. \n\nDr. Mesraoua is the recipient of two research Grants, as the Lead Principal Investigator (750.000 USD and 250.000 USD) from the Qatar National Research Fund (QNRF) and the Hamad Hospital Internal Research Grant (IRGC), on the following topics : “Continuous EEG Monitoring in the ICU “ and on “Alpha-lactoalbumin , proof of concept in the treatment of epilepsy” .Dr Mesraoua is a reviewer for the journal \"seizures\" (Europeen Epilepsy Journal ) as well as dove journals ; Dr Mesraoua is the author and co-author of many peer reviewed publications and four book chapters in the field of Epilepsy and Clinical Neurology",institutionString:"Weill Cornell Medical College in Qatar",institution:{name:"Weill Cornell Medical College in Qatar",country:{name:"Qatar"}}},{id:"282429",title:"Prof.",name:"Covanis",middleName:null,surname:"Athanasios",slug:"covanis-athanasios",fullName:"Covanis Athanasios",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/282429/images/system/282429.jpg",biography:null,institutionString:"Neurology-Neurophysiology Department of the Children Hospital Agia Sophia",institution:null},{id:"190980",title:"Prof.",name:"Marwa",middleName:null,surname:"Mahmoud Saleh",slug:"marwa-mahmoud-saleh",fullName:"Marwa Mahmoud Saleh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/190980/images/system/190980.jpg",biography:"Professor Marwa Mahmoud Saleh is a doctor of medicine and currently works in the unit of Phoniatrics, Department of Otolaryngology, Ain Shams University in Cairo, Egypt. She got her doctoral degree in 1991 and her doctoral thesis was accomplished in the University of Iowa, United States. Her publications covered a multitude of topics as videokymography, cochlear implants, stuttering, and dysphagia. She has lectured Egyptian phonology for many years. Her recent research interest is joint attention in autism.",institutionString:"Ain Shams University",institution:{name:"Ain Shams University",country:{name:"Egypt"}}},{id:"259190",title:"Dr.",name:"Syed Ali Raza",middleName:null,surname:"Naqvi",slug:"syed-ali-raza-naqvi",fullName:"Syed Ali Raza Naqvi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259190/images/system/259190.png",biography:"Dr. Naqvi is a radioanalytical chemist and is working as an associate professor of analytical chemistry in the Department of Chemistry, Government College University, Faisalabad, Pakistan. Advance separation techniques, nuclear analytical techniques and radiopharmaceutical analysis are the main courses that he is teaching to graduate and post-graduate students. In the research area, he is focusing on the development of organic- and biomolecule-based radiopharmaceuticals for diagnosis and therapy of infectious and cancerous diseases. Under the supervision of Dr. Naqvi, three students have completed their Ph.D. degrees and 41 students have completed their MS degrees. He has completed three research projects and is currently working on 2 projects entitled “Radiolabeling of fluoroquinolone derivatives for the diagnosis of deep-seated bacterial infections” and “Radiolabeled minigastrin peptides for diagnosis and therapy of NETs”. He has published about 100 research articles in international reputed journals and 7 book chapters. Pakistan Institute of Nuclear Science & Technology (PINSTECH) Islamabad, Punjab Institute of Nuclear Medicine (PINM), Faisalabad and Institute of Nuclear Medicine and Radiology (INOR) Abbottabad are the main collaborating institutes.",institutionString:"Government College University",institution:{name:"Government College University, Faisalabad",country:{name:"Pakistan"}}},{id:"58390",title:"Dr.",name:"Gyula",middleName:null,surname:"Mozsik",slug:"gyula-mozsik",fullName:"Gyula Mozsik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/58390/images/system/58390.png",biography:"Gyula Mózsik MD, Ph.D., ScD (med), is an emeritus professor of Medicine at the First Department of Medicine, Univesity of Pécs, Hungary. He was head of this department from 1993 to 2003. His specializations are medicine, gastroenterology, clinical pharmacology, clinical nutrition, and dietetics. His research fields are biochemical pharmacological examinations in the human gastrointestinal (GI) mucosa, mechanisms of retinoids, drugs, capsaicin-sensitive afferent nerves, and innovative pharmacological, pharmaceutical, and nutritional (dietary) research in humans. He has published about 360 peer-reviewed papers, 197 book chapters, 692 abstracts, 19 monographs, and has edited 37 books. He has given about 1120 regular and review lectures. He has organized thirty-eight national and international congresses and symposia. He is the founder of the International Conference on Ulcer Research (ICUR); International Union of Pharmacology, Gastrointestinal Section (IUPHAR-GI); Brain-Gut Society symposiums, and gastrointestinal cytoprotective symposiums. He received the Andre Robert Award from IUPHAR-GI in 2014. Fifteen of his students have been appointed as full professors in Egypt, Cuba, and Hungary.",institutionString:"University of Pécs",institution:{name:"University of Pecs",country:{name:"Hungary"}}},{id:"277367",title:"M.Sc.",name:"Daniel",middleName:"Martin",surname:"Márquez López",slug:"daniel-marquez-lopez",fullName:"Daniel Márquez López",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/277367/images/7909_n.jpg",biography:"Msc Daniel Martin Márquez López has a bachelor degree in Industrial Chemical Engineering, a Master of science degree in the same área and he is a PhD candidate for the Instituto Politécnico Nacional. His Works are realted to the Green chemistry field, biolubricants, biodiesel, transesterification reactions for biodiesel production and the manipulation of oils for therapeutic purposes.",institutionString:null,institution:{name:"Instituto Politécnico Nacional",country:{name:"Mexico"}}},{id:"196544",title:"Prof.",name:"Angel",middleName:null,surname:"Catala",slug:"angel-catala",fullName:"Angel Catala",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/196544/images/system/196544.jpg",biography:"Angel Catalá studied chemistry at Universidad Nacional de La Plata, Argentina, where he received a Ph.D. in Chemistry (Biological Branch) in 1965. From 1964 to 1974, he worked as an Assistant in Biochemistry at the School of Medicine at the same university. From 1974 to 1976, he was a fellow of the National Institutes of Health (NIH) at the University of Connecticut, Health Center, USA. From 1985 to 2004, he served as a Full Professor of Biochemistry at the Universidad Nacional de La Plata. He is a member of the National Research Council (CONICET), Argentina, and the Argentine Society for Biochemistry and Molecular Biology (SAIB). His laboratory has been interested for many years in the lipid peroxidation of biological membranes from various tissues and different species. Dr. Catalá has directed twelve doctoral theses, published more than 100 papers in peer-reviewed journals, several chapters in books, and edited twelve books. He received awards at the 40th International Conference Biochemistry of Lipids 1999 in Dijon, France. He is the winner of the Bimbo Pan-American Nutrition, Food Science and Technology Award 2006 and 2012, South America, Human Nutrition, Professional Category. In 2006, he won the Bernardo Houssay award in pharmacology, in recognition of his meritorious works of research. Dr. Catalá belongs to the editorial board of several journals including Journal of Lipids; International Review of Biophysical Chemistry; Frontiers in Membrane Physiology and Biophysics; World Journal of Experimental Medicine and Biochemistry Research International; World Journal of Biological Chemistry, Diabetes, and the Pancreas; International Journal of Chronic Diseases & Therapy; and International Journal of Nutrition. 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At the National Cancer Institute (National Institute of Health, Bethesda, MD) he worked as a research associate on the molecular biology of selenium and its role in health and disease. After postdoctoral collaborations with Carlos Gutierrez-Merino (University of Extremadura, Spain) and Dario Alessi (University of Dundee, UK), he established his own laboratory in 2008. 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Fungal infectious illness prevalence and prognosis are determined by the exposure between fungi and host, host immunological state, fungal virulence, and early and accurate diagnosis and treatment. \r\nPatients with both congenital and acquired immunodeficiency are more likely to be infected with opportunistic mycosis. Fungal infectious disease outbreaks are common during the post- disaster rebuilding era, which is characterised by high population density, migration, and poor health and medical conditions.\r\nSystemic or local fungal infection is mainly associated with the fungi directly inhaled or inoculated in the environment during the disaster. The most common fungal infection pathways are human to human (anthropophilic), animal to human (zoophilic), and environment to human (soilophile). Diseases are common as a result of widespread exposure to pathogenic fungus dispersed into the environment. \r\nFungi that are both common and emerging are intertwined. In Southeast Asia, for example, Talaromyces marneffei is an important pathogenic thermally dimorphic fungus that causes systemic mycosis. Widespread fungal infections with complicated and variable clinical manifestations, such as Candida auris infection resistant to several antifungal medicines, Covid-19 associated with Trichoderma, and terbinafine resistant dermatophytosis in India, are among the most serious disorders. \r\nInappropriate local or systemic use of glucocorticoids, as well as their immunosuppressive effects, may lead to changes in fungal infection spectrum and clinical characteristics. Hematogenous candidiasis is a worrisome issue that affects people all over the world, particularly ICU patients. CARD9 deficiency and fungal infection have been major issues in recent years. Invasive aspergillosis is associated with a significant death rate. Special attention should be given to endemic fungal infections, identification of important clinical fungal infections advanced in yeasts, filamentous fungal infections, skin mycobiome and fungal genomes, and immunity to fungal infections.\r\nIn addition, endemic fungal diseases or uncommon fungal infections caused by Mucor irregularis, dermatophytosis, Malassezia, cryptococcosis, chromoblastomycosis, coccidiosis, blastomycosis, histoplasmosis, sporotrichosis, and other fungi, should be monitored. \r\nThis topic includes the research progress on the etiology and pathogenesis of fungal infections, new methods of isolation and identification, rapid detection, drug sensitivity testing, new antifungal drugs, schemes and case series reports. It will provide significant opportunities and support for scientists, clinical doctors, mycologists, antifungal drug researchers, public health practitioners, and epidemiologists from all over the world to share new research, ideas and solutions to promote the development and progress of medical mycology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/4.jpg",keywords:"Emerging Fungal Pathogens, Invasive Infections, Epidemiology, Cell Membrane, Fungal Virulence, Diagnosis, Treatment"},{id:"5",title:"Parasitic Infectious Diseases",scope:"Parasitic diseases have evolved alongside their human hosts. In many cases, these diseases have adapted so well that they have developed efficient resilience methods in the human host and can live in the host for years. Others, particularly some blood parasites, can cause very acute diseases and are responsible for millions of deaths yearly. Many parasitic diseases are classified as neglected tropical diseases because they have received minimal funding over recent years and, in many cases, are under-reported despite the critical role they play in morbidity and mortality among human and animal hosts. The current topic, Parasitic Infectious Diseases, in the Infectious Diseases Series aims to publish studies on the systematics, epidemiology, molecular biology, genomics, pathogenesis, genetics, and clinical significance of parasitic diseases from blood borne to intestinal parasites as well as zoonotic parasites. We hope to cover all aspects of parasitic diseases to provide current and relevant research data on these very important diseases. In the current atmosphere of the Coronavirus pandemic, communities around the world, particularly those in different underdeveloped areas, are faced with the growing challenges of the high burden of parasitic diseases. At the same time, they are faced with the Covid-19 pandemic leading to what some authors have called potential syndemics that might worsen the outcome of such infections. Therefore, it is important to conduct studies that examine parasitic infections in the context of the coronavirus pandemic for the benefit of all communities to help foster more informed decisions for the betterment of human and animal health.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",keywords:"Blood Borne Parasites, Intestinal Parasites, Protozoa, Helminths, Arthropods, Water Born Parasites, Epidemiology, Molecular Biology, Systematics, Genomics, Proteomics, Ecology"},{id:"6",title:"Viral Infectious Diseases",scope:"The Viral Infectious Diseases Book Series aims to provide a comprehensive overview of recent research trends and discoveries in various viral infectious diseases emerging around the globe. The emergence of any viral disease is hard to anticipate, which often contributes to death. A viral disease can be defined as an infectious disease that has recently appeared within a population or exists in nature with the rapid expansion of incident or geographic range. This series will focus on various crucial factors related to emerging viral infectious diseases, including epidemiology, pathogenesis, host immune response, clinical manifestations, diagnosis, treatment, and clinical recommendations for managing viral infectious diseases, highlighting the recent issues with future directions for effective therapeutic strategies.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/6.jpg",keywords:"Novel Viruses, Virus Transmission, Virus Evolution, Molecular Virology, Control and Prevention, Virus-host Interaction"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"May 15th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:4,numberOfPublishedChapters:286,numberOfPublishedBooks:27,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"14",title:"Cell and Molecular Biology",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",annualVolume:11410,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",annualVolume:11411,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null,editorialBoard:[{id:"241413",title:"Dr.",name:"Azhar",middleName:null,surname:"Rasul",fullName:"Azhar Rasul",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRT1oQAG/Profile_Picture_1635251978933",institutionString:null,institution:{name:"Government College University, Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"178316",title:"Ph.D.",name:"Sergey",middleName:null,surname:"Sedykh",fullName:"Sergey Sedykh",profilePictureURL:"https://mts.intechopen.com/storage/users/178316/images/system/178316.jfif",institutionString:null,institution:{name:"Novosibirsk State University",institutionURL:null,country:{name:"Russia"}}}]},{id:"17",title:"Metabolism",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",annualVolume:11413,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},{id:"18",title:"Proteomics",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRqB9QAK/Profile_Picture_1626163237970",institutionString:null,institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"profile.detail",path:"/profiles/425601",hash:"",query:{},params:{id:"425601"},fullPath:"/profiles/425601",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()