\r\n\tRadiation monitoring deals with the sampling and measurement of different products found in different radiation pathways from the environment ending with consumption in humans. Gamma-spectroscopy is the main tool for measurement of these radiations.
\r\n
\r\n\tThe aim of this book is to investigate the radionuclide concentrations in the most consumable food products, air, water and soil. Particularly, it is essential to investigate the radiations level in the surroundings of a nuclear facility.
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1. Introduction
Herbal medicine is commonly used to treat skin disorders, and the ethnobotanical remedies are developed in different regions, based on local plants. In particular, two different systems, Ayurvedic herbs, estabilished in India, and the traditional Chinese medicine, which uses the combination of different herbs, are known. In the occidental world, the use of herbal medicine is relative to purified extracts, often substituted for synthetic chemical drugs. In the last years, we assisted an intense return, in the occidental world, to herbal medicine, probably because we are living in the green revolution [1]. The use of vegetable raw materials in the preparation of products for local application on the skin dates back to ancient times. The term phytocosmetics, from Greek kosmesis, which means adorn, and phytos, which means plant, is used to indicate the predominant and preferential use of botanical derivatives in cosmetic products. The vegetable field is an inexhaustible source of raw materials that, transformed by various processes, find many applications, both as functional substances and as excipients of the products. Contrary to some 50 years ago, when the cosmetic use of medicinal herbs was largely based on the mere observation of the traditional use, today, numerous scientific studies on the properties of plant-based drugs, as well as advanced knowledge on technical-scientific ones that allow to extract the active principles contained in the plants, are available. The herbal phytonutrient offers an enormous amount and heterogeneity of substances, which, by means of various extracellular processes, give rise to extracts with various functional applications. The active constituents of plants are in fact represented by a complex mixture of substances of different chemical nature (tannins, pectins, saponins, flavonoids, essences, fixed oils, etc.) whose concentration in the extract is essentially linked to the particular extraction process. The most widely used vegetable extracts are glycolic extracts, hydroalcoholic extracts, distilled water, dried extracts, oily extracts, essential oils, and vegetable oils. Vegetable oils are obtained by cold squeezing of plant drugs whose active ingredients are characterized by oily texture. The oil is predominantly made up of polyunsaturated fatty acids rich in triglycerides and also contains antioxidant substances, liposoluble vitamins, and the so-called insaponifiable fraction, a complex mixture of substances of extreme interest both from the dermatological and cosmetic field. Olive oil, coconut oil, wheat germ oil, borage oil, and almond oil are the main types of vegetable oils used in cosmetics. Compared to other types of oily ingredients, the advantage of using vegetable oils in cosmetics and cosmeceuticals lies primarily in their particular lipid composition, which is very close to the structure and function of that of the physiologic sebum present in the interstices and the surface of the corneal layer of the epidermis. The very high affinity to the skin sebum gives them an excellent ability to restore the physiological skin barrier by means of a protective, filmogenic, and emollient action. In this chapter, we describe the advantageous effects of ozonated olive oil in the treatment of skin disorders; in fact, olive oil is considered one of the most excellent foods for diet, but it has anti-inflammatory action, so it is used for skin disease. In the chapter, we report information about the safety and mechanism of action on microorganism and on wound healing.
1.1. Olive oil
Olive oil consists of glycerides, such as oleic, arachidic, palmitic, linoleic, and stearic acids, and of phenolic compounds. It is very important in the culinary use, but it has important applications in cosmetic and pharmaceutical fields. The olive tree Olea europaea is a common feature of the Mediterranean landscape, with the olive fruit and olive oil being the basic elements in the nutrition of civilizations around the Mediterranean basin for millennia. The principal reason is due to the tree’s climatic requirements, which are found in limited areas of the earth’s surface [2]. This longevous tree integrates and identifies economically, socially, and culturally with the inhabitants of this land and determines its rural landscape [3]. Even olive leaves have been used in popular medicine. The therapeutic and health properties of olive oil have been known for millennia so much that Hippocrates advised the juice of fresh olives to cure mental illness and wraps to heal ulcers. During the Middle Ages and during the Renaissance, olive oil was used to cure gynecological infections and was considered useful in the treatment of heart disease, fever, and hypertension.
1.1.1. Beneficial effects of olive oil: health properties
Virgin olive oil has been and still is the subject of numerous studies that have attributed great properties to it, both in the field of health and in cosmetology. Various epidemiological studies have shown that the incidence of inflammatory, cardiovascular, and tumor illnesses is generally lower in Mediterranean European countries (such as Greece, Italy, and Spain) than in other western and northern countries [4]. This can be attributed to the high consumption of olive oil in the Mediterranean diet, which contributes to the daily requirement of vitamin E, essential fatty acids, and specific antioxidants, particularly represented by phenolic compounds and tocopherols. In addition, antioxidants have a primary role in resistance to oxidation and hence in the stability of olive oil and have been shown to exert numerous beneficial effects on the human body. The antioxidants’ protective effect is mainly due to their ability to inhibit the action of oxygen free radicals, indicated by the acronym ROSs [5]. ROSs are highly reactive species represented by atoms or molecules with one or more electrons being dissipated, capable of generating the so-called oxidative stress. When the organism is subject to an increase in oxidative stress, an increase of F2-isoprostanes (IsoPs) in plasma levels and of urinary excretion is observed. IsoPs are a type of novel compound, structurally similar to prostaglandins, biosynthesized in vivo from the free radical–catalyzed peroxidation of arachidonate independent of the cyclooxygenases (COX) [6]. Oxidative stress seems to be the main reason for many chronic and degenerative diseases and skin aging. More specifically, ROSs induce (i) DNA mutations and protein alterations that are the basis of carcinogenesis [7]; (ii) oxidation of low density lipoproteins (LDL) involved in the formation of atherosclerotic plaques [8]; (iii) the onset of chronic intestinal inflammatory diseases, such as Crohn’s disease [9]; (iv) probable onset of neurodegenerative diseases, such as Parkinson’s disease [10]; and (v) cellular aging, by lipid peroxidation of the membranes, which become more permeable and less effective. All this evidence allows us to understand the importance of antioxidants, even from exogenous sources such as diet. The beneficial effects, and in particular the antitumor activity, of olive oil on human health are attributed to the high content of phenolic substances with high antioxidant power [11]. Phenolic compounds, in synergy with α-tocopherol and coenzyme Q, protect cells from oxidative damage by contrasting the toxic effects of ROS [12]. Through various epidemiological studies, the correlation between the consumption of virgin olive oil and the risk of onset of certain types of cancer has been demonstrated, such as breast [13], lung [14], colon [15], ovary [16], pancreas [17], and prostate cancer [18]. It has been shown that among the phenolic compounds, one of the most biologically active is hydroxytyrosol (3,4-DHPEA) that is able to inhibit the 5-lipoxygenase enzyme, by reducing the production of leukotriene B4 in the leukocytes, originating from the metabolism of the eicosanoids [19]. In addition, hydroxytyrosol is able to inhibit in vitro the oxidation of LDL [20] and in vivo [21] the aggregation of platelets [22]. Some experimental studies have also shown that the phenolic extract of virgin olive oil and two isolated compounds, the dialdehyde form of hydroxytyrosol (3,4-DHPEA-EDA) and thiol (p-HPEA-EDA), are able to inhibit uncontrolled cellular proliferation by blocking the cell cycle at G0/G1 and to induce apoptosis in some lines of cancer cells, as demonstrated for HL60 cells of promyelocytic human leukemia [23, 24]. However, compounds with greater biological activity are those containing the ortho-diphenol residues; it has been shown that 3,4-DHPEA and 3,4-DHPEA-EDA are more effective than p-HPEA and p-HPEA-EDA in protecting DNA from damage caused by oxidation [25]. In an in vitro study, by examining different virgin olive oil extracts, a chemoprotective effect was demonstrated on HL60 cell lines in relation to their composition but not to the total content of phenolic substances [26]. ROS production is also closely related to inflammatory processes in which the cyclooxygenase enzymes (COX-1 and COX-2), belonging to the oxidoreductase class, catalyze the conversion of arachidonic acid into prostaglandins. The p-HPEA-EDA, also called oleocanthal, has the ability to inhibit the activity of such enzymes and has a pharmacological effect similar to that of ibuprofen, which belongs to the class of nonsteroidal anti-inflammatory drugs [27]. It has also been shown that the consumption of olive oil may improve blood pressure regulation and cholesterol content in the blood; these events, together with the inhibition of platelet aggregation and the reduction of LDL oxidation, are important to prevent the onset of atherosclerotic plaques and, in general, cardiovascular pathologies [28, 29]. Olive oil also contains many monounsaturated fatty acids, including oleic acid, which is a key component of cellular membranes and can progressively replace polyunsaturated fatty acids. Membranes rich in monounsaturated fatty acids are more fluid and less subject to lipid peroxidation [30]. Some studies have also shown that regular intake of this food may result in a reduction in the risk of developing diabetes [31]. The therapeutic properties of olive oil include a laxative effect and stimulation of biliary function [32]. Finally, some studies on animal models have shown that the intake of olive oil can help to counteract the damage caused by epidermal ultraviolet radiation [33].
1.1.2. Dermatological and cosmetic properties
In recent years, in a number of fields, including cosmetics, there has been a renewed interest in materials of natural origin, particularly those of vegetable origin. Since ancient times, olive oil has been known not only for its high nutritional power but also for its cosmetic and therapeutic properties [34]. In 1971, Thiers was still pointing to its potential use in the cosmetic sector. To date, olive oil is certainly the most appreciated natural ingredient, alongside jojoba and avocado oils. The topical application of olive oil may be advised for its soothing action and its beneficial effects on eczema, surface wounds, and burns [35, 36]. In particular, the presence of phytosterols and triterpenoid compounds offers revitalizing and soothing properties for the skin. Vitamins E and A have an intense antioxidant action and have the ability to prevent irritation and aging of the skin, to help maintain its softness, smoothness, stability, and elasticity. As a result, in the cosmetic field, olive oil can be used to prevent signs of aging as a soothing emollient for dry skin and to strengthen hair [37]. Indeed, it is very often a component of lotions, lip balms, shampoos, bath oils, and massage oils. From a dermatologic point of view, olive oil has also proven to have antimicrobial activity, in vitro, against some positive and negative Gram and various types of fungi, including Candida spp. [38]. Some components of olive oil, especially certain aliphatic aldehydes, inhibit elastase activity; this enzyme is involved in the virulence process [39]. Olive oil is an important component of some topical formulations used in the treatment of inflammatory and mycotic skin diseases [40]. The unsaponifiable fraction is rich in numerous active ingredients with sebum-regulating and moisturizing properties, as well as emollients; it can be a component of cosmetic products (in the form of creams, balms, gels, etc.) for the treatment of delicate, dry, and cracked skin. In fact, the unsaponifiable fraction is very useful in the case of particularly vulnerable skin, such as that of infants and children, or in the case of xerotic skin, such as that of the elderly. Skin hydration is above all important in the neonatal period and especially in premature infants: some clinical trials have been conducted to highlight the beneficial effects of emollient topical treatment [41, 42]. Furthermore, the unsaponifiable fraction exerts a good photoprotective effect on ultraviolet exposed skin: various studies have shown that the application of olive oil may reduce the incidence of skin epithelial tumors on UV-B–exposed mice compared to a control group [43, 44]. The unsaponifiable fraction can also be an additive in makeup products with the purpose of making them easier to apply, softer, and smoother. Butter contains high quantities of squalene (which is the most important constituent of sebum), waxes, and esters that guarantee high penetration of the skin. Butter is ideal for massages or as a vehicle for other active ingredients used in skin care. It acts also as an emollient and moisturizing agent, promoting skin elasticity and preventing the onset of wrinkles. Finally, it can be used as an additive in photoprotective products or in skin hygiene products due to its ability to neutralize aggressive detergent action.
An interesting and powerful way to use extra virgin olive oil is with ozone. The process of ozonization allows the properties of ozone gas to be combined with those of olive oil; the result is a peerless compound. Since ancient times, ozone has also been used in a large number of medical indications [45, 46, 47, 48, 49].
2. Ozone
Ozone is an oxygen derivative and is known primarily for its ecological role in the Earth’s balance, absorbing most of the ultraviolet radiation from the sun and preventing it from reaching humans in a harmful way. It is an unstable gas that cannot be stored; in fact, it dissolves in very short time. Ozone is totally neutral to the human body, and in fact, it does not (i) modify pH, (ii) irritate skin or mucous membranes, (iii) damage hair or clothing, (iv) interact with drugs, and (v) cause allergic reactions. This molecule has been subjected to countless studies, and in particular, its strong oxidation capacity has been tested in order to underline its disinfectant and sanitizing properties principally applied as a disinfectant of drinking and waste water [45, 46, 47]. To this purpose, the dedicated design and construction of equipment for the production of gaseous ozone for air and water purification are increasing. But research into the properties of ozone has yielded promising results in biological applications, thus confirming the ozone activity in stimulating natural cell defenses and increasing their energy availability. Indeed, since ancient times, ozone has also been used in a large number of medical indications [48, 49]. Scientific studies have shown that ozone, while being highly unstable, can be trapped inside vegetable oils. These are composed of triglycerides in which saturated and unsaturated fatty acids are present, which have the ability to retain ozone, thus allowing them to prolong their use. In addition, the greater the amount of unsaturated fats present, the greater the amount of ozone that will be retained [50]. Therefore, when extra virgin olive oil is ozonated, the produced product combines the beneficial properties of extra virgin olive oil with those of ozone. There are countless ozone-based products on the market, and in particular, in our laboratory, we have developed Bioxoil™, an ozonated extra virgin olive oil available in pharmacies. This product is exclusively made from olive cultivars from Puglia and Salento and the oil is ozonated by an innovative patented method (number: M2011A001045 titled: “Process for the ozonization of a vegetable oil“) that confers quality and efficiency in various fields of application; in particular, Bioxoil™ is indicated for the treatment of acne, herpes, psoriasis, fungal infections, bed sores, and wounds in general, due to its healing and disinfectant properties (Figure 1).
Figure 1.
Bioxoil™ products. The Bioxoil products have different applications. Bioxoil with a red label is indicated for bed sores; the sky blue label is indicated as soothing medication; the green label is indicated for herpes labialis; the pink label is indicated for acne; and the orange tag is indicated for mycosis.
Bioxoil™ is produced from extra virgin olive oils from two local cultivars, Ogliarola and Cellina, in Salento (Apulia, Italy). The ozone reacts with unsaturated compounds through the known Criegee mechanism. The quality of extra virgin oil is very important to obtain a higher grade of ozonization; for this reason, during the process, it is necessary to control different physical and chemical parameters. Of these parameters, the most important is the temperature, and in fact, during the reaction, the temperature increases provoking an alteration of antioxidant content. The oils’ peroxide content and acidity value that indicate the level of hydrolytic modification and primary and secondary oxidation of oil are analyzed and reported in Table 1. Peroxide index (PI) and acidity index (AI) after ozonization of oils increase with respect to relative controls. In particular, Cellina’s oil sample has an acidity index of 0.2% and a peroxide index of 12 mmol O2 kg−1, while related ozonated oil has an AI of 1.8% and a PI of 533 mmol O2 kg−1. Ogliarola’s oil sample presents an acidity index of 0.3% and a peroxide index of 13 mmoli O2 kg−1, while respective ozonated oil has an AI of 1.3% and the PI increases to 677 mmoli O2 kg−1.
Sample
Acidity index (AI), % (means ± SD)
Peroxide index (PI), mmol O2 kg−1, (means ± SD)
Ogliarola olive oil
0.2 ± 0.03
12 ± 1.2
Ozonated Ogliarola olive oil
1.8 ± 0.02
533 ± 1.5
Cellina olive oil
0.3 ± 0.02
13 ± 1.5
Ozonated Cellina olive oil
1.3 ± 0.01
677 ± 1.6
Table 1.
Physicochemical parameters of Ogliarola olive oil and Cellina olive oil after ozonization procedure.
In our experiments, the ability of ozone to react with olive oil and in particular with the carbon-carbon double bonds present in unsaturated fatty acids was demonstrated by gas liquid chromatography (GLC). The composition of fatty acids of each olive oil and respective ozonated oil are analyzed by GLC. Data demonstrate that the amount of oleic acid decreases in both ozonized oil samples: in Cellina’s ozonated oil, we observed a 30% reduction, while in Ogliarola’s ozonized oil, the reduction was about 26% (Table 2). During the ozonization reaction, ozone etches mainly the double bond of acid oleic, the most abundant fatty acid in olive oil (about 80%). This explains the decrease in oleic acid and the contemporary appearance of new compounds, which are the reaction’s products, among which are nonanal aldehyde and nonanoic acid, both compounds with nine carbon atoms (Table 2). In both cultivar ozonized oils, the composition of fatty acids changes, showing a gradual decrease in unsaturated fatty acids (C 18:1, C 18:2), with a gradual increase in ozone doses.
Composition of fatty acids (%)
Cellina
Cellina
Ogliarola
Ogliarola
Control
Ozonated oil
Control
Ozonated oil
Palmitic acid
12.45
11.91
11.89
11.30
Linolenic acid
5.57
2.19
4.96
2.06
Cis-oleic acid
70.27
39.82
67.00
41.25
Trans-oleic acid
8.22
6.68
7.88
7.2
Stearic acid
3.48
1.29
3.32
3.22
Nonanal
0
11.69
0
10.07
Nonanoic acid
0
1.36
0
1.98
Table 2.
Composition of fatty acids in olive oil samples Cellina and Ogliarola.
3. Biocompatibility of ozonated olive oil with skin
The skin is the largest organ of the body and is the major barrier between the inside and outside of our body. It is formed of two main layers: the epidermis, a thin outer portion, and the dermis, the connective tissue layer of skin. This portion is involved in the thermoregulation process, and the resident dermal fibroblasts secrete collagen, elastin, and substances that offer support and elasticity of the skin. The epidermis is subdivided into four layers: (i) the stratum germinativum (SG) that provides the germinal cells necessary for the regeneration of epidermidis; (ii) the stratum spinosum (SS), in which the cells divided in the SG start to accumulate many desmosomes on their surface; (iii) the stratum granulosum (SGR), in which the keratinocytes accumulate dense basophilic keratohyalin granules that contain lipids, which help to form a waterproof barrier; and (iv) the stratum corneum (SC), the outermost layer, in which the cells are dead. The skin is constantly exposed to the environmental stress of pollutants or cigarette smoke, for example, so it is necessary for the wellness of the skin to preserve it from oxidative stress. To this purpose, there are a variety of antioxidants that include glutathione peroxidase, superoxide dismutase, catalases, and nonenzymatic low-molecular weight antioxidants such as vitamin E isoforms, vitamin C, glutathione (GSH), uric acid, and ubiquinol. Interestingly, the distribution of antioxidants in the SC follows a gradient with higher concentrations in deeper layers [51].
The biocompatibility of Bioxoil™ was investigated by MTT assay on fibroblast 3T3 and on keratinocytes HaCaT and compared with ozonated dulcis almond oils and nonozonated olive oil as controls. The MTT test values the cell metabolic activity and, in particular, measures the activity of oxidoreductase by reduction of the tetrazolium bromide dye in formazan. The dulcis almond oil was chosen because it is largely used in cosmetics, and as it is an oil, it is a possible vector of ozone. Data reported in Figure 2 demonstrate the Bioxoil™ biocompatibility for both cell types. The viability of cells never significantly decreased in relation to the control and was the same as the nonozonated oil. Conversely, once ozonated, 10% of dulcis almond oil had a very significant negative effect on the viability of fibroblasts and keratinocytes but not when dulcis almond oil was nonozonated. Interestingly, the vitality test demonstrated that when these cells are exposed to a mixture of ozonated olive oil and 10% of ozonated dulcis almond oil (3:1), the adverse event induced by the ozonated almond oil alone was partially prevented (Figure 2).
Figure 2.
MTT assay on fibroblasts and keratinocytes.
3.1. Biological action of ozonides
By combining the beneficial properties of extra virgin olive oil with that of ozone, the ozonated extra virgin olive oil becomes very powerful for the topical treatment of acute and chronic skin lesions. The ozonides generated during the ozonization procedure possess many properties including a high germicidal activity on fungi, yeasts, viruses, and bacteria; activation of local microcirculation; stimulation of granulation and tissue growth; and revitalization of epithelial tissues.
3.1.1. Germicidal activity
The excessive consumption of antibiotics for the treatment of infectious diseases has fuelled the drug resistance phenomenon, i.e., the microorganisms are resistant to antibiotics. Therefore, it is necessary to develop new molecules with antibiotic properties, preferably natural and nonsynthetic. In fact, this research is divided into the field of synthetic molecules produced by the chemical/pharmaceutical industry and the field of natural active compounds, in which plant extracts are studied also by the use of green chemistry. The plants are able to withstand fungal and bacterial infections and therefore their secondary metabolites can be applied in the field of medicinal herbs. Maoz and Neeman in their research reported an antifungal action of olive oil due to the high content of oleic acid [52]. The ozonated oil increases this natural capacity, because ozone acts on microorganisms, thanks to its greater oxidizing power; in fact, it is able to break down the macromolecules that are the basis of the vital integrity of bacterial cells, fungus, protozoa, and viruses. The ozone in contact with the microorganism’s lipoproteins forms H2O2 and the final products of lipid oxidation (LOP); H2O2 assures bacteriostatic and bactericidal activity, while final lipid oxidation products have induction activity and reactivate metabolic functions (Figure 3). Nagayoshi et al. [53] reported the capability of ozone to destroy Gram-positive and -negative microorganisms, and in particular, Gram-negative bacteria are more sensitive.
Figure 3.
Molecular mechanism of antimicrobial activity of ozonides: the oxygen internalized from ozonides reacts with the proton/protons in order to form H2O2 that has a bacteriostatic and bactericidal activity.
For virus inactivation, a higher gas dosage than that required for bacteria is necessary. The ozone oxidates and subsequently inactivates the specific viral receptors used to bind the cell wall for virus invasion [54]. We tested the antibacterial activity of Bioxoil™ on mycete Epidermophyton floccosum, demonstrating its efficacy in the inhibition of mycete’s growth in liquid and agar medium; the bacteriostatic effect is obtained in the presence of 5 μl/ml of ozonated olive oil, and the bactericidal effect is obtained in the presence of 15 μl/ml (Figure 4).
Figure 4.
Growth curves of mycete Epidermophyton floccosum in liquid culture medium: 1A, 2A, and 3A are the positive controls with 12.5, 25, and 50 mg/ml of nonozonized olive oil, respectively; 1B, 2B, and 3B are ozonized olive oil samples with 12.5, 25, and 50 mg/ml of ozonized olive oil, respectively; 4 is the negative control.
The antibacterial activity of Bioxoil™ was also tested on Staphylococcus aureus and Staphylococcus epidermidis, and its efficacy in inhibiting microbes growing both in liquid medium culture and in agar medium was demonstrated. We defined the minimal inhibitory concentration (MIC) of 50 mg⋅ml−1 for S. aureus and of 25 mg⋅ml−1 for S. epidermidis. This study confirms that ozonated olive oil has antimicrobial properties, which can be exploited for cutaneous infections, by slow release of O3, which displays effective disinfectant and stimulatory activities that lead to rapid healing.
3.1.2. Biological activity
The ozonides easily penetrate the cell membrane and, thanks to their biological properties, stimulate skin cells and improve the tropism of the skin by promoting wound healing and repair of ulcers of various kinds; from the experiments, it was found that topical application of products based on ozonides has determined a considerable increase of fibroblasts resulting in increased production of collagen, glycosoaminoglycans, and formation of elastic and reticular fibers. The healing of skin lesions includes complex movements like tissue hemorrhage, inflammation, re-epithelialization, granulation tissue, and finally remodeling. These events involve the coordination of many cell types and matrix proteins, which are important for the control of the various stages of tissue repair. Previous studies have shown that endogenous growth factors, such as fibroblast growth factor (FGF), growth factor derived from platelets (PDGF), the TGF-β factor, and vascular endothelial growth factor (VEGF) are important regulators in the healing of wounds [55]. They are released by macrophages, fibroblasts, and keratinocytes at the site of injury and participate in the regulation of re-epithelialization, formation of granulation tissue, collagen synthesis, and neovascularization [56, 57, 58]. The beneficial effects of ozone in the treatment of sores are due to the decrease of bacterial infection and the increasing oxygen tension in the wound. In the literature, it is reported that after exposure to ozone transcription factors are activated, such as NF-kB, and these are important regulators of the inflammatory response and tissue repair process [58]. In conclusion, the ozonated olive oil can accelerate acute cutaneous wound repair, by stimulation of dermal fibroblast, and the ozonized oil has shown to be effective against Gram-negative and -positive bacteria, mycetes, and viruses, so it can be used for the cure of infections.
4. Conclusions
The goal of pharmacological research has always been that of finding drugs that can cure diseases or soothe the pain that derives from them, and this research has evolved over the years in an extraordinary way both in the field of medical knowledge and scientific studies that are more and more powerful and sophisticated. Medicinal herbs, long popular in many parts of the world, are increasingly spreading in the western world and represent a large commercial market with an estimated annual growth of 25%, often replacing synthetic drugs. Among the medicinal herbs, particular interest is reserved to olive oil, called “yellow gold” by the Egyptians for its innumerable beneficial properties. Herbal trade today sees many products based on olive oil for both hygiene and personal care. In the field of oil-based products, particular interest is directed to products containing ozonated oil; these products are the result of the union of the beneficial properties of olive oil with those of ozone. Ozonated oil is the most practical, innovative, harmless, and noninvasive of the techniques of application developed in the field of ozone therapy over the last 130 years. It has demonstrated interesting therapeutic results. The biological effects of ozone include antimicrobial activity (antibacterial, antiviral, and antifungal), antalgic action, and improved O2 metabolism [59]. In this chapter, the possible applications of the Bioxoil™ products, already distributed in pharmacies and herbalist’s shops, have been described; its production line includes five different products characterized by different concentrations of ozonides such as to allow the use for the most varied skin affections. Bioxoil with the highest content of ozonides is indicated for the treatment of bedsores at first and second stages, thanks to its anti-inflammatory and cicatrizing properties, Bioxoil with medium concentrations, but different from each other, is indicated for the treatment of herpes labialis, mycosis, and onychomycosis and for acne due to its antimicrobial action. Finally, Bioxoil with the lowest ozonide content is indicated to soothe contact or allergic irritations. The exceptional usability of the product and its completely natural origin offers a vast market.
\n',keywords:"extra virgin olive oil, ozone, herbal medicine, antimicrobial activity, wound healing",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/58960.pdf",chapterXML:"https://mts.intechopen.com/source/xml/58960.xml",downloadPdfUrl:"/chapter/pdf-download/58960",previewPdfUrl:"/chapter/pdf-preview/58960",totalDownloads:1747,totalViews:897,totalCrossrefCites:1,totalDimensionsCites:3,totalAltmetricsMentions:0,impactScore:1,impactScorePercentile:74,impactScoreQuartile:3,hasAltmetrics:0,dateSubmitted:"May 30th 2017",dateReviewed:"December 18th 2017",datePrePublished:"March 21st 2018",datePublished:"January 30th 2019",dateFinished:"January 23rd 2018",readingETA:"0",abstract:"Extra virgin olive oil has been mainly produced and consumed in Mediterranean countries since ancient times; olive oil is one of the principal ingredients in the Mediterranean diet, and it constitutes the main source of nutritional fat. Aside from the high nutritional content of olive oil, it is also known for its cosmetic and therapeutic properties. In 1956, Thiers obtained satisfactory results in the treatment of scleroderma, stating that olive oil and its derivatives could be considered “a new group of therapeutic agents.” Hincky reported the beneficial properties of olive oil in the treatment of dry, senescent and sensitive skins. This has opened a new perspective for the use of the olive fruit, thus contributing to the increase in research about new applications. One such application is ozonized olive oil, which combines the properties of ozone with those of olive oil, to obtain a peerless compound. The composition of olive oil makes it a suitable vehicle for cutaneous absorption, as it is able to stabilize ozone, which is a highly reactive molecule. The oxidant power of ozone has interesting effects on microorganism and on wound healing.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/58960",risUrl:"/chapter/ris/58960",book:{id:"6302",slug:"herbal-medicine"},signatures:"Elisabetta Carata, Bernardetta Anna Tenuzzo and Luciana Dini",authors:[{id:"103116",title:"Prof.",name:"Luciana",middleName:null,surname:"Dini",fullName:"Luciana Dini",slug:"luciana-dini",email:"luciana.dini@unisalento.it",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"University of Salento",institutionURL:null,country:{name:"Italy"}}},{id:"206595",title:"Dr.",name:"Bernardetta Anna",middleName:null,surname:"Tenuzzo",fullName:"Bernardetta Anna Tenuzzo",slug:"bernardetta-anna-tenuzzo",email:"bernardetta.tenuzzo@unisalento.it",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"206596",title:"Dr.",name:"Elisabetta",middleName:null,surname:"Carata",fullName:"Elisabetta Carata",slug:"elisabetta-carata",email:"elisabetta.carata@unisalento.it",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_1_2",title:"1.1. Olive oil",level:"2"},{id:"sec_1_3",title:"1.1.1. Beneficial effects of olive oil: health properties",level:"3"},{id:"sec_2_3",title:"1.1.2. Dermatological and cosmetic properties",level:"3"},{id:"sec_5",title:"2. Ozone",level:"1"},{id:"sec_6",title:"3. Biocompatibility of ozonated olive oil with skin",level:"1"},{id:"sec_6_2",title:"3.1. Biological action of ozonides",level:"2"},{id:"sec_6_3",title:"3.1.1. Germicidal activity",level:"3"},{id:"sec_7_3",title:"3.1.2. Biological activity",level:"3"},{id:"sec_10",title:"4. Conclusions",level:"1"},{id:"sec_13",title:"Abbreviations",level:"1"}],chapterReferences:[{id:"B1",body:'Shenefelt PD. Herbal Treatment for Dermatological Disorders. In: Wachtel-Galor S, editor. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd ed. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. 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Department of Biological and Environmental Science and Technology, Italy
'},{corresp:null,contributorFullName:"Bernardetta Anna Tenuzzo",address:null,affiliation:'
Department of Biological and Environmental Science and Technology, Italy
Department of Biological and Environmental Science and Technology, Italy
CNR-Nanotech Centro Ecotekne, Italy
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\n
1. Introduction
\n
Increasing growth in human population has necessitated increased agricultural production. Agricultural production in the last five decades has been said to increase more than three times. Other factors responsible for increased agricultural production include technological advancement toward green revolution and expansion of soil for agricultural production [1, 2]. It has been estimated that agricultural sector provides about 24 million tons of food globally [1] with accompanying health risks and threat on ecosystems [3]. We cannot do without agriculture because food is a necessity across the globe, but the impact of agriculture on the environment is also evident. For example, it has been documented that about 21% of greenhouse gas emission comes from agriculture. The negative influence of agriculture on the environment, aquatic lives and human health have necessitated improvement in agricultural production, involving effective and efficient ways of handling agricultural solid wastes [4].
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The global leaders have been mandated to prioritize production of more food and energy for increasing human population which is estimated to exceed 10 billion by 2050 as well as to tackle the impacts already caused. However, this mandate is expected to be achieved with lower emissions of pollutants, zero solid waste and less fossil fuel [5, 6]. The future prediction for increased agricultural production involves food production for human population, industrial needs, and animal feed [7]. However, every step of agricultural production, processing and consumption generates quantities of agricultural solid wastes, depending on the type of agricultural produce or product, processing techniques and purpose of use.
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The agricultural sector is one of the main sectors generating the largest quantities of agricultural solid wastes, which may be allowed to accumulate indiscriminately and constitute nuisance to global health and threat to food security or used as raw materials for bio-economy [8, 9]. The benefits of recycling of agricultural solid wastes include reduction of greenhouse gas emissions and use as fossil fuel as well as contributing significantly to the development of new green markets, creation of jobs, production of bio-energy and bio-conversion of agricultural solid wastes to animal feed [10, 11].
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The emphasis on the management of agricultural solid wastes cannot be overemphasis. Agricultural solid wastes are generated from many sources. One of such sources are pesticides, including herbicides and insecticides. It has been estimated that the global food production would fall by an estimate of about 42% if the use of pesticide is completely stopped [12]. The influence of agricultural solid wastes on human health, animal health, and the environment is significant and all hands must be on deck to tackle the menace posed by mismanagement of agricultural solid wastes. Agricultural solid wastes are mismanaged largely owing to ignorance. Many of the farmers and household managers who generate these wastes do not know how to effectively manage them. Many of them do not know the health implications of what they toy with, while some who know are ‘handicapped’. Year after year, large tons of agricultural solid wastes are being produced, with an annual increase of about 7.5% [13, 14]. In many parts in developing countries, agricultural solid wastes are indiscriminately dumped or burnt in public places, thereby resulting in the generation of air pollution, soil contamination, a harmful gas, smoke and dust and the residue may be channeled into a water source thereby polluting the water and aquatic environment [15, 16, 17].
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\n
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2. Classification and causes/sources of agricultural solid wastes
\n
Agricultural solid wastes are produced mainly from farming activities. However, it is not limited to the production but other activities associated with farming and food chain. Every stage and phase of the agricultural-food chain can generate significant agricultural solid wastes. The broad classification of agricultural solid wastes includes the following:
Animal production solid wastes;
Food and meat processing solid wastes;
Crop production solid wastes;
On-farm medical solid wastes;
Horticultural production solid wastes;
Industrial agricultural solid wastes;
Chemical wastes.
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Animal production solid wastes—animal production solid wastes are solid wastes generated from the production of livestock for whatever purposes. Examples of such wastes include bedding/litter, animal carcasses, damaged feeders, and water-trough, etc.
Food and meat processing solid wastes—this class of agricultural solid wastes are produced from the processing of crop or animal products for human consumption, such as abattoir or slaughterhouses. Examples of food and meat processing agricultural solid wastes include hoofs, bones, feathers, banana peels, etc.
Crop production solid wastes—crop solid wastes are associated with agricultural solid wastes typically produced from agricultural activities involving crop production. Examples of such agricultural solid wastes are crop residues, husks, etc.
On-farm medical solid wastes—on-farm medical solid wastes refer to solid wastes that are generated from the use of drugs, insecticides or vaccines used on or animals. Examples of such wastes include vaccine wrappers or containers, disposable needles, syringes, etc.
Horticultural production solid wastes—this group of agricultural solid wastes refer to solid wastes generated from cultivation and maintenance of horticultural plants and landscape for beautification. Examples of such wastes are prunings and grass cuttings.
Industrial agricultural solid wastes—agricultural produce and livestock are not only cultivated and produced for dietary consumption. They are used for other uses and it is not unlikely that such activities result in agricultural solid wastes. Wood processing and cuttings readily come to mind as a source of agricultural solid wastes. Paper production using agricultural products as raw materials also generate some quantities of agricultural solid wastes.
Chemical wastes—chemical wastes in this context have to do with agricultural solid wastes generated from the use of pesticides, insecticides and herbicides on the farm or store, such as pesticide containers or bottles. Agricultural activities still depend on the use of pesticides, insecticides, and herbicides, being handled by many uneducated and untrained farmers in developing countries, resulting in abuse by these uneducated farmers [18, 19]. Some uneducated farmers mishandle pesticide containers, thereby resulting in unpredictable environmental hazards. It has been reported that about 2% of pesticides remain in the containers after use, which some ignorant and uneducated users may throw in the ponds or on the open field resulting in food poisoning, environmental and water pollution, causing death of many lives [20, 21].
\n\n
Agricultural solid wastes are usually generated through agricultural activities involving preparation, production, storage, processing and consumption of agricultural produce, livestock and their products. Agricultural solid wastes are produced via:
Farming activities
Poor road network
Poor electricity or lack of rural electrification
Inadequate drying technique and storage facilities
Food spoilage
Kitchen-generated agricultural solid wastes
\n
Farming activities—the main source of agricultural solid waste generation is agriculture. Beginning from land clearing till harvest, every phase of farming activities results in the generation of agricultural waste. From preparing the pen for the arrival of the animals to the farm, preparation of pasture/paddock till the animals are slaughtered and sold, solid wastes are generated.
Poor road network for transporting harvested produce from the farm to the market or storage is another avenue of generating large quantities of agricultural solid wastes. This happens largely as a result of the bad road network in some developing countries, which may result in a road accident or delay of agricultural produce from farms to markets. When road accident occurs, perishable agricultural produce result easily in wastage, and when delayed, the same result may occur. The spoilt produce is either thrown away on the road or separated to be discarded once the farmer gets to the market. Figure 1 shows agricultural produce being transported in a city in Nigeria.
Poor electricity or lack of rural electrification—the epileptic power supply and lack of rural electrification in some parts of developing countries with significant agricultural activities are contributing in no small measure to the generation of agricultural solid wastes. Stable electricity could have facilitated the cold storage of the harvested produce and thereby reduce spoilage and consequently agricultural solid wastes.
Inadequate drying technique and storage facilities—spoilage of much agricultural produce could be prevented with adequate drying techniques. If farmers have access to adequate drying technique or moisture monitor, it would have gone a long way in militating against food spoilage and agricultural solid waste, thereby enhancing food security and reducing the impact of agricultural solid waste on human health and the environment. Many of the farmers depend largely on the unpredictable solar system to dry their produce before they are stored, as well as rely on the conventional method of moisture monitoring which is neither effective nor accurate. Inadequate monitoring of moisture content in grain before storage has been reported to result in aflatoxin infestation. Aflatoxin is produced by Aspergillus flavus. Aflatoxin infestation is both a cause and a product of food spoilage [23] and its contamination of food and livestock feed can lead to significant annual crop losses globally [24].
It has been estimated that about 10% of global crop harvest is destroyed by filamentous fungi through contamination of food and feed with mycotoxins. Aflatoxins have been reported to produce liver carcinogens, impair human health in developing countries, and result in the huge economic losses, in the U.S. corn alone amounting to about $280 million annually. The economic losses could be as high as 1 billion dollars if other crop-infestation such as cotton, peanuts and tree nuts are included. Aflatoxins B1 and B2 which cause preharvest and postharvest crop infestation are produced by Aspergillus flavus [23].
Food spoilage is another important source or cause of agricultural solid wastes. It has been estimated that about 40% of food is wasted in the US alone annually. This waste has been estimated to cost about 162 billion dollars Natural Resources Defense Council [25]. Pest and insect infestation may also increase wastage owing to spoilage.
Kitchen-generated agricultural solid wastes: in most cases, the end result of agricultural activities is family consumption. Usually, the consumption of agricultural produce at the family level is not without the production of agricultural solid wastes. Some of these wastes are generated out of necessity. For example, orange peels and banana peels are discarded as agricultural solid wastes in many homes. However, agricultural solid wastes may also be generated unintentionally, arising from food spoilage. Kitchen-generated agricultural solid wastes become significant when restaurants are included as kitchens (commercial kitchens). Of all the kitchen wastes considered in cities in China, agricultural solid wastes (food wastes) constitute between 88 and 94% [26]. Figure 2, Tables 1 and 2 respectively show home-generated agricultural solid wastes, the composition of kitchen wastes and nutritional characteristics of kitchen wastes in selected cities in China.
\n\n
Figure 1.
Transportation of agricultural produce in Nigeria. Source: Vanguard Newspaper [22].
\n
Figure 2.
Home-generated agricultural solid wastes.
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n\n
\n
Cities
\n
Food waste
\n
Paper
\n
Metal
\n
Bone
\n
Wood
\n
Fiber
\n
Plastic
\n
\n\n\n
\n
Guiyang
\n
92.09
\n
0.80
\n
0.10
\n
5.20
\n
1.01
\n
0.10
\n
0.70
\n
\n
\n
Shenyang
\n
92.16
\n
0.42
\n
0.08
\n
5.22
\n
1.31
\n
0.12
\n
0.69
\n
\n
\n
Chongqing
\n
94.13
\n
0.31
\n
0.00
\n
5.24
\n
0.02
\n
0.13
\n
0.19
\n
\n
\n
Wuhan
\n
88.40
\n
2.80
\n
0.20
\n
5.20
\n
1.00
\n
0.30
\n
2.10
\n
\n\n
Table 1.
Composition of kitchen wastes in Chinese cities (unit: %).
3. Influence of agricultural solid waste on human health and environment
\n
The influence of agricultural production on human, health, change in climate, animal healthy and the environment cannot be over-emphasized. For example, it has been suggested the greenhouse gas emissions need to be reduced drastically to avert the impeding threat on the planet, earth and its inhabitants to avert temperature rise by at least an average rise of 35.6°F [27]. Animal production has been indicted to produce about 37 and 65% of global methane and nitrous oxide emissions respectively [28], which are more potent than carbon dioxide. Indiscriminate burning of agricultural solid wastes produces climate-relevant emissions. Improper handling of agricultural solid wastes influence change in climate and change in climate in turn hampers food production. The effects of indiscriminate disposal of agricultural solid wastes cannot be overemphasized. Some of the effects are outlined below:
Flood
Health and environmental implication
Food security
\n
Flood: One major cause of flood has been the blockage of waterways. Waterways are blocked primarily when human beings build on waterways or when the canals or waterways are blocked by solid wastes. In an agricultural environment, the indiscriminate dumping of agricultural solid wastes can result in blockage of waterways which when that happens will result in floods which may result in losses of lives and properties.
Health and environmental implication—arising from indiscriminate burning of generated wastes. Indiscriminate dumping and burning of agricultural solid waste have resulted in pollution, a threat to human lives as well as other environmental problems, calling for global attention, although these wastes can be recycled to improve soil fertility, being rich in nutrient required for sustainable agricultural production [13, 29, 30]. Figure 3 shows the agricultural solid wastes being dumped in open space.
Food security and agricultural solid wastes: Continuous human population growth has been linked with increased agricultural activities which consequently results in increased generation of agricultural solid wastes. There are currently about 7.5 billion people around the globe and a significant portion of this population still do not have enough food to eat. Figure 4 is a chart comparing the human population according to continents while Table 3 shows the current human population parameters according to continents. The effects of food insecurity are enormous, ranging from poor health, slow progress in education and employment development [34]. One of the important 17 Global Sustainable Goals is to end hunger, achieve food security and improve nutrition and promote sustainable agriculture by 2030. Unfortunately, 10 years ahead of the deadline for this goal, there are still about 821 hungry people across the globe [34]. It has been argued that the main problem of food insecurity is not that we are not producing enough food, but agricultural solid wastes, mainly food wastage is responsible. Africa and Asia have been noted as the fast-growing population in the world, incidentally, these are the regions with most food insecure people and inefficient waste management [33, 35]. It has been estimated that one-third of the food we produce annually is lost or wasted, costing about one trillion US dollars annually. Wastage occurs mostly in developing countries during the production and supply chain while it occurs mainly in developed countries on the plate [34]. Agricultural solid wastes can be recycled as nonconventional feed ingredients to enhance food security by enhancing animal protein production [36]. Figures 5 and 6 respectively show food wastage chart in America and estimate of unconsumed food by an average American family.
\n\n
Figure 3.
Dumping of agricultural solid wastes at the public. Sources: Akande and Olorunnisola [31] and Olayiwola et al. [32].
\n
Figure 4.
Current population of the seven continents. Source: Worldometers [33].
\n
\n
\n
\n
\n
\n
\n
\n\n
\n
Rank
\n
Continent
\n
Population
\n
Area, km2\n
\n
Density, P/km2\n
\n
World population share, %
\n
\n\n\n
\n
1
\n
Asia
\n
4,641,054,775
\n
31,033,131
\n
150
\n
59.5
\n
\n
\n
2
\n
Africa
\n
1,340,598,147
\n
29,648,900
\n
45
\n
17.2
\n
\n
\n
3
\n
Europe
\n
747,636,026
\n
22,134,900
\n
34
\n
9.6
\n
\n
\n
4
\n
North America
\n
592,072,212
\n
21,330,000
\n
28
\n
7.6
\n
\n
\n
5
\n
South America
\n
430,759,766
\n
17,461,112
\n
25
\n
5.5
\n
\n
\n
6
\n
Australia/Oceania
\n
42,677,813
\n
8,486,460
\n
5
\n
0.6
\n
\n
\n
7
\n
Antarctica
\n
0
\n
13,720,000
\n
0
\n
0.0
\n
\n\n
Table 3.
List of continents ranked by current human population parameters.
Unconsumed food by an average American family. Source: Rescuing Leftover Cuisine [25].
\n
Figure 6.
Food wastage chart in America. Source: Rescuing Leftover Cuisine [25].
\n
\n
\n
4. Effective management of agricultural solid wastes
\n
There are options on how agricultural solid wastes could be handled. This chapter is necessary because of the need to focus people’s attention on efficient ways of managing these wastes. Traditionally, shafts from palm oil processing could be used as fuel in fuel wood for cooking and heating. In the recent time, some of these wastes are put into better uses. Some of these agricultural solid wastes could be used as additives in cement mixes, water glass manufacturing, paper making, ethanol production, animal feed, electricity and biogas generation, heavy metal removal, mulching, organic fertilizers, and compost. An effective means of managing agricultural solid wastes is to recycle them to produce useful products. This can be achieved through:
Compositing/organic manure
Substrates for edible fungi cultivation
Nonconventional feed ingredient
Traditional soap making
Alternative energy sources and bio-fuel production
Production of silica
\n
Compositing: Li et al. [26] recommended that kitchen wastes, largely agricultural solid waste from food wastage could be used as an animal feed via sterilization, fertilizer via composting and bioenergy via anaerobic digestion. These wastes are important candidates for compositing owing to their high organic matter content and nutrients, although their high salt, moisture content and oil may impair composting.
Substrates for mushroom cultivation: mushroom has been grown on different agricultural solid wastes as substrates [32, 37]. Steps involved in mushroom cultivation and its benefits are highlighted by Olayiwola et al. [32].
Nonconventional feed ingredient. Several attempts have been made to feed agricultural solid wastes to livestock as a means of recycling as well as a cheap source of feed for raising animal-source protein. A nonconventional feed ingredient, mycomeat has also been produced from agricultural solid wastes. The wastes served as substrate and a mixture of the substrates and the cultivated fungi (mushroom) was feed to broiler chicks, as a nonconventional feed ingredient, mycomeat [36, 37, 38, 39, 40] fed some agricultural solid wastes to albino rats and recommended processing of the wastes in order to obtain a better result. Adebiyi et al. [41] recommended the combination of 40% cassava peel +40% concentrate +20% watermelon wastes for feeding grower pigs. Poultry feathers could be used for several products instead of being indiscriminately discarded or burnt. Traditional, feathers are used for decoration, pillows and could be converted as nonconventional feed ingredients to feed livestock.
\n\n
Feathers are a group of agricultural solid wastes that are generated in large quantities annually as a by-product of poultry processing [42]. It may account for about 6% of the total live weight of a mature chicken. They are rich in a keratinous protein, which is a fibrous and insoluble protein [43]. Adejumo et al. [44] reported protein content of between 84 and 87% for feather meal, hence, effective use of feather meal as livestock feed ingredient may payoff than its use as other produce. Feathers can be used in erosion control, for diaper filling, as biodegradable composites, in the greenhouse industry, animal feeds, upholstery, artwork, paper alternatives, light-weight structural materials, water filtration fibers, fabric, aircraft, and automotive industries and thermal insulation [45, 46]. The major limitation to the use of feathers as a livestock feed ingredient is the insoluble keratinous protein, but recent studies are suggesting ways of overcoming the limitation [38, 44, 47]. It has been documented that about 80% of kitchen wastes, largely food wastage are fed to pigs in China, although direct feeding of kitchen waste has not been without restriction in China, arising from the concern of foot and mouth disease [48] Processing of agricultural solid wastes could enhance their value for feeding pigs [49, 50]. The effect of dried sweet orange (Citrus sinensis) peel has been tested on humoral immune response of broiler chickens [51] as well as maize replacement and its effect evaluated on growth performance and carcass qualities of broiler chickens [52], instead of allowing them to accumulate and constitute a nuisance as agricultural solid wastes.
Traditional soap making: traditional technology exists in Africa decades ago for turning some of the agricultural solid wastes into useful products. Cocoa pods which could turn agricultural solid wastes are usually either allowed to naturally decompose and enrich the soil or are used to make black soap, which may be used for washing dishes or bathing.
Alternative energy source and bio-fuel production: agricultural solid wastes can be converted to green energy through anaerobic digestion [9]. High protein and fat contents of these wastes may impair anaerobic digestion stability, as well as unavailability of efficient technology required for disposal of biogas residues [53]. However, pre-treatment techniques such as mechanical (sonication), chemical addition (acid or alkali), oxidative (ozone), biological (enzyme addition), thermal ad osmotic (freezing and sodium chloride treatment) may improve the physical and chemical properties of the wastes, thereby enhancing their solubilization of organic particles, sterilization effect as well as the promotion of their subsequent recycling (biogas production) [54, 55]. Despite many challenges confronting its production, bio-fuel and bio-energy attract many hopes as a sustainable renewable energy source, which tend to promote rural and regional development, reduction of CO2 emission, creation of job opportunity as well as replacing the energy from nonrenewable fossil fuel with green energy [56, 57, 58]. Agricultural solid wastes (rich in cellulose, hemicellulose, starch, lipids and proteins) which are produced in large tons and burnt in open-field or allowed to accumulate in some developing countries may be channeled toward bio-fuel generation [59, 60]. Key players and political leaders, particularly in developing countries should team up with researchers to scale up the conversion of biomass to alternative energy sources or bio-fuel generation. This is expected not only to reduce the health menace arising from open-field agricultural solid wastes burning or dumping but to improve energy production and reduce economic losses of waste disposal as well.
Production of silica: Production of silica: Silicon, the 2nd most abundant nonmetallic element in the earth crust with an atomic weight of 28 [61, 62] forms silica and silicates. It is rarely found in its elemental state owing to its affinity for oxygen [63]. It has been reported as a beneficial trace element, widely distributed in foods. Its health benefits include improvement of the structural integrity of nail, hair, skin, immunity, bone mineralization, bone calcification and reduces the occurrence of atherosclerosis [64, 65, 66]. In the presence of hydrochloric acid and other gastric fluids in the GIT, silicon compounds are degraded into bioavailable forms of silicic acid (ortho, meta, di, and tri-silicates) [67] and are diffused into different organs of the body [68, 69]. Silicon quantity decreases with age and tends to be more in plants than animal-sources, although dietary sources are low in silicon and may need to be supplemented in diets through other means [65, 70, 71, 72]. It does not bond with plasma proteins, hence, about 75% of plasma silicon is excreted within a few hours after ingestion [68, 73]. Agricultural solid wastes are potential sources of silica. Silica has been produced from agricultural solid wastes such as corn cob, rice husk, bagasse and rice straw using chemical, thermal, and microbial methods [74, 75, 76, 77, 78, 79].
\n\n
\n
\n
5. Conclusion
\n
Food wastage is an important source of agricultural solid wastes. Hence, the prevention of food wastage at all levels before they are created will salvage some of these wastes and prevent unnecessary ill-health and environmental disadvantages as well as huge economic losses. This can be achieved through proper education and awareness of those involved with agricultural activities at all levels as well as being a little more generous by feeding hungry people with fresh food instead of keeping them till they are spoilt. There are hungry people everywhere in the world. Feeding animals saves food scraps and bioconversion of agricultural by-products, which may turn to agricultural solid wastes if their values are not enhanced and will go a long way in preventing such wastes as well. Composting and conversion of agricultural solid wastes to a renewable energy source is another effective way of managing agricultural solid wastes. It is high time attention is focused on turning these huge potential agricultural solid wastes to wealth, particularly in developing countries. To make our world safer for us to live, all hands must be on deck. Research activities should be geared toward commercial scaling of some productive findings made toward the efficient recycling of agricultural wastes.
\n
Proper awareness should be made to everyone involved in agricultural activities whether at a middleman or woman, farmer, or consumer on the effects of indiscriminate disposal of agricultural solid wastes and benefits of efficient management of agricultural solid wastes. Political leaders, particularly in developing countries should be open-minded and formulate policies that ensure the efficient recycling of agricultural solid wastes and appropriate funds should be earmarked to achieving this. Attention should be focused on minimizing wastage by creating a more efficient sustainable agricultural supply chain through the development of sustainable durable markets and improving rural infrastructures such as electrification, roads, and storage [34].
\n
It should also be noted that huge revenue could be generated from the conversion of agricultural solid wastes into useful products, as it has the potential of employing people if well-harnessed. Hence, its importance goes beyond the health implication but includes income generation for individual and governments which receive tax from companies and individual working in such establishments involved in the conversion of wastes to useful products. Also, it could contribute significantly to minimizing civil unrest plaguing some villages in developing countries. Some idle youths used to foment trouble could be scarce to find if they are gainfully employed, and that gainful employment could be companies or individuals who are efficiently engaging in turning agricultural solid wastes to wealth. Recycling of agricultural solid wastes into useful products could generate other sets of agricultural solid wastes, which may serve as raw materials for another useful products, thereby necessitating the continuous recycling of agricultural solid wastes until every potential waste is converted into wealth.
\n
\n
Conflict of interest
We have no conflicts of interest.
\n',keywords:"agricultural solid waste, animal feed, composting, environmental safety, recycling",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/73517.pdf",chapterXML:"https://mts.intechopen.com/source/xml/73517.xml",downloadPdfUrl:"/chapter/pdf-download/73517",previewPdfUrl:"/chapter/pdf-preview/73517",totalDownloads:1581,totalViews:0,totalCrossrefCites:5,dateSubmitted:"July 3rd 2020",dateReviewed:"August 14th 2020",datePrePublished:"December 15th 2020",datePublished:"April 21st 2021",dateFinished:"October 8th 2020",readingETA:"0",abstract:"The role of the agricultural sector in human development and economic development cannot be overemphasized. Awareness for increased agricultural production is on the increase, arising from the need to feed the ever-increasing human population. Interestingly, almost all agricultural activities generate wastes, which are generated in large quantities in many countries. However, these wastes may constitute a serious threat to human health through environmental pollution and handling them may result in huge economic loss. Unfortunately, in many developing countries where large quantities of these wastes are generated, they are not properly managed because little is known about their potential risks and benefits if properly managed. There are studies that address some of the challenges of agricultural solid wastes as well as suggestions on how they can be properly managed. In this chapter, we intend to explore the major sources of agricultural solid wastes, their potential risks, and how they can be properly managed.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/73517",risUrl:"/chapter/ris/73517",signatures:"Isaac Oluseun Adejumo and Olufemi Adebukola Adebiyi",book:{id:"9873",type:"book",title:"Strategies of Sustainable Solid Waste Management",subtitle:null,fullTitle:"Strategies of Sustainable Solid Waste Management",slug:"strategies-of-sustainable-solid-waste-management",publishedDate:"April 21st 2021",bookSignature:"Hosam M. Saleh",coverURL:"https://cdn.intechopen.com/books/images_new/9873.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83962-560-2",printIsbn:"978-1-83962-559-6",pdfIsbn:"978-1-83962-561-9",isAvailableForWebshopOrdering:!0,editors:[{id:"144691",title:"Prof.",name:"Hosam",middleName:null,surname:"Saleh",slug:"hosam-saleh",fullName:"Hosam Saleh"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"276527",title:"Dr.",name:"Isaac Oluseun",middleName:null,surname:"Adejumo",fullName:"Isaac Oluseun Adejumo",slug:"isaac-oluseun-adejumo",email:"smogisaac@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"328699",title:"Dr.",name:"O.A.",middleName:null,surname:"Adebiyi",fullName:"O.A. Adebiyi",slug:"o.a.-adebiyi",email:"femibiyi01@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"University of Ibadan",institutionURL:null,country:{name:"Nigeria"}}}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Classification and causes/sources of agricultural solid wastes",level:"1"},{id:"sec_3",title:"3. Influence of agricultural solid waste on human health and environment",level:"1"},{id:"sec_4",title:"4. Effective management of agricultural solid wastes",level:"1"},{id:"sec_5",title:"5. Conclusion",level:"1"},{id:"sec_9",title:"Conflict of interest",level:"1"}],chapterReferences:[{id:"B1",body:'\nFood and Agriculture Organization of the United Nations (FAO). Strategic work of FAO for sustainable food and agriculture. 2017. 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Available from: https://northerly.ag/causes-of-agricultural-waste/ [Accessed: 12 August 2020]\n'},{id:"B13",body:'\nWang HY, Liu S, Zhai LM, Zhang JZ, Ren TZ, Fan BQ , et al. Preparation and utilization of phosphate biofertilizers using agricultural waste. Journal of Integrative Agriculture. 2015;14:158-167\n'},{id:"B14",body:'\nWang SR, Ru B, Dai GX, Sun WX, Qiu KZ, Zhou JS. Pyrolysis mechanism study of minimally damaged hemicellulose polymers isolated from agricultural waste straw samples. Bioresource Technology. 2015;190:211-218\n'},{id:"B15",body:'\nVarma VS, Yadav J, Das S, Kalamdhad AS. Potential of waste carbide sludge addition on earthworm growth and organic matter degradation during vermicomposting of agricultural wastes. Ecological Engineering. 2015;83:90-95\n'},{id:"B16",body:'\nKarak T, Sonar I, Nath JR, Paul RK, Das S, Boruah RK, et al. Struvite for composting of agricultural wastes with termite mound: Utilizing the unutilized. Bioresource Technology. 2015;187:49-59\n'},{id:"B17",body:'\nWang B, Dong F, Chen M, Zhu J, Tan J, Xinmei F, et al. Advances in recycling and utilization of agricultural wastes in China: Based on environmental risk, crucial pathways, influencing factors, policy mechanism the tenth international conference on waste management and technology (ICWMT). Procedia Environmental Sciences. 2016;31:12-17\n'},{id:"B18",body:'\nAdejumo IO, Ologhobo AD, Babalola TO. Effect of pre-planting seed dressers on serum enzymes of laying chickens. American Chemical Science Journal. 2015;9(2):1-5. DOI: 10.9734/ACSJ/2015/19687\n'},{id:"B19",body:'\nAdejumo IO, Ologhobo AD, Adedeji IA, Ogunjimi SI. Status of exposure of bio-systems to restricted aluminium phosphide pesticide in Kano state, Nigeria. International Journal of Scientific Research in Knowledge. 2014;2(7):306-312\n'},{id:"B20",body:'\nDien BV, Vong VD. Analysis of Pesticide Compound Residues in Some Water Sources in the Province of Gia Lai and DakLak. Vietnam: Vietnam Food Administrator; 2006\n'},{id:"B21",body:'\nObi FO, Ugwuishiwu BO, Nwakaire JN. Agricultural waste concept, generation, utilization and management. Nigerian Journal of Technology. 2016;35(4):957-964\n'},{id:"B22",body:'\nVanguard Newspaper. 2020. Available from: www.vanguardngr.com/2020/07/fg-signs-mou-to-curb-risks-in-transporting-agricultural-produce [Accessed: 03 August 2020\ufeff]\n'},{id:"B23",body:'\nKlich MA. Aspergillus flavus: The major producer of aflatoxin. Molecular Plant Pathology. 2007;l(8):713-722. DOI: 10.1111/j.1364-3703.2007.00436.x\n'},{id:"B24",body:'\nNierman WC, Yu J, Fedorova-Abrams ND, Losada L, Cleveland TE, Bhatnagar D, et al. Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes aflatoxin contamination of food and feed. Genome Announcements. 2015;3(2):e00168-e00115. DOI: 10.1128/genomeA.00168-15\n'},{id:"B25",body:'\nRescuing Leftover Cruisine. 2020. Available from: https://www.rescuingleftovercuisine.org/challenge [Accessed: 03 August 2020]\n'},{id:"B26",body:'\nYangyang L, Jin Y, Li J, Chen Y, Gong Y, Li Y, et al. Current situation and development of kitchen waste treatment in China. In: The Tenth International Conference on Waste Management and Technology (ICWMT), Procedia Environmental Sciences. Vol. 31. 2016. pp. 40-49\n'},{id:"B27",body:'\nJeremy W, Adrian W, Hughes John K, Mairi B, Richard M. Energy and the food system. Philosophical Transactions of the Royal Society B. 2010;365:2991-3006. DOI: 10.1098/rstb.2010.0172\n'},{id:"B28",body:'\nFAO. Livestock Long Shadow. 2006. Available from: http://www.fao.org/3/a-a0701e.pdf [Accessed: 13 August 2020]\n'},{id:"B29",body:'\nLiu Y, Dong JX, Liu GJ, Yang HN, Liu W, Wang L, et al. Co-digestion of tobacco waste with different agricultural biomass feedstocks and the inhibition of tobacco viruses by anaerobic digestion. Bioresource Technology. 2015;189:210-216\n'},{id:"B30",body:'\nIbrahim RA. Tribological performance of polyester composites reinforced by agricultural wastes. Tribology International. 2015;90:463-466\n'},{id:"B31",body:'\nAkande OM, Olorunnisola AO. Potential of briquetting as a waste-management option for handling market-generated vegetable waste in Port Harcourt, Nigeria. Recycling. 2018;3(2):11. DOI: 10.3390/recycling3020011\n'},{id:"B32",body:'\nAkintola OA, Idowu OO, Lateef SA, Adebayo GA, Shokalu AO, Akinyoola OI. The Use of Waste Management Techniques to Enhance Household Income and Reduce Urban Water Pollution, Elements of Bioeconomy, Krzysztof Biernat. Rijeka: IntechOpen; 2019. DOI: 10.5772/intechopen.85580\n'},{id:"B33",body:'\nWorldometers. 2020. Available from: worldometers.info/geography/7-continents [Accessed: 03 August 2020]\n'},{id:"B34",body:'\nWorld Food Programme. 2020. Available from: https://www.wfp.org/zero-hunger [Accessed: 04 August 2020]\n'},{id:"B35",body:'\nFAO, IFAD and WHO. The State of Food Security and Nutrition in the World: Safeguarding Against Economic Slowdown and Downturns. Rome, Italy: World Food Programme; 2019. pp. 1-32\n'},{id:"B36",body:'\nAdejumo IO, Adetunji CO, Adeyemi OS. Influence of UV light exposure on mineral composition and biomass production of mycomeat produced from different agricultural substrates. The Journal of Agricultural Science. 2017;62(1):51-59. DOI: 10.2298/JAS1701051A\n'},{id:"B37",body:'\nAdetunji CO, Adejumo IO. Nutritional assessment of mycomeat produced from different agricultural substrates using wild and mutant strains from Pleurotus sajor-caju during solid state fermentation. Animal Feed Science and Technology. 2017;224:14-19 http://dx.doi.org/10.1016/j.anifeedsci.2016.12.004\n\n'},{id:"B38",body:'\nOluwaseun AC, Oluseun AI. Efficacy of crude and immobilized immobilized enzymes from Bacillus licheniformis for production of biodegraded feather meal and their assessment on chickens. Environmental Technology and Innovation. 2018;11:116-124. DOI: 10.1016/j.eti.2018.05.002\n'},{id:"B39",body:'\nOluseun AI, Adetunji CO, Nwonuma CO, Alejolowo OO, Maimako R. Evaluation of selected agricultural solid wastes on biochemical profile and liver histology of albino rats. Food & Feed Research. 2017;44(1):73-79. DOI: 10.5937/FFR1701073A\n'},{id:"B40",body:'\nOluwaseun AC, Oluseun AI. Potency of agricultural wastes in mushroom (Pleurotus sajor-caju) biotechnology for feeding broiler chicks (Arbor acre). International Journal of Recycling of Organic Waste in Agriculture. 2018;8:37-45. DOI: 10.1007/ s40093-018-0226-6\n'},{id:"B41",body:'\nAdebiyi OA, Awotale HO, Adejumo IO, Osinowo OA, Muibi MA, Nwaodu OB. Performance, serum and haematological indices of pigs fed watermelon waste based-diet. Tropical Animal Production Investigation. 2019;22(1):10-16\n'},{id:"B42",body:'\nFakhfakh-Zouari N, Hmidet N, Haddar AS, Kanoun S, Nasri M. A novel serine metallokeratinase from a newly isolated Bacillus pumilus A1 grown on chicken feather meal: Biochemical and molecular characterization. Applied Biochemical Biotechnology. 2010;162:329-344\n'},{id:"B43",body:'\nSwetlana N, Jain PC. Feather degradation by strains of bacillus isolated from decomposing feathers. Brazilian Journal of Microbiology. 2010;41:196-200. DOI: 10.1590/S1517-83822010000100028\n'},{id:"B44",body:'\nAdejumo IO, Adetunji CO, Kunle O, Sonia ON. Chemical composition and amino acid profile of differently processed feather meal. The Journal of Agricultural Science. 2016;61(3):237-246. DOI: 10.2298/JAS1603237A\n'},{id:"B45",body:'\nComis D. Chicken Feather Is the Eco-Friendly Plastics of the 21st Century. Washington, D.C., USA: Agricultural Research Service, USDA; 1998\n'},{id:"B46",body:'\nSchmidt WF. Innovative feather utilization strategies. In: Auburn AL, editor. Proceedings of the 1998 National Poultry Waste Management Symposium. Springdale, Arkansas: Auburn University Printing Services; 1998. pp. 276-282\n'},{id:"B47",body:'\nOluseun AI, Oluwaseun AC. Production and evaluation of biodegraded feather meal using immobilized and crude enzyme from Bacillus subtilis on broiler chickens. Brazilian Journal of Biological Sciences. 2018;5(10):405-416. DOI: 10.21472/bjbs.051017\n'},{id:"B48",body:'\nChen T, Jin Y, Qiu X, Chen X. A hybrid fuzzy evaluation method for safety assessment of food-waste feed based on entropy and the analytic hierarchy process methods. Expert Systems with Applications. 2014;41:7328-7337\n'},{id:"B49",body:'\nAdebukola AO, Michael S, Oluwanifemi AO, Oluseun AI. Effects of extruded rice bran based diets on the performance, intestinal microbiota and morphology of weaned pigs. Agricultura Tropica Et Subtropica. 2018;51(1):13-19. DOI: 10.2478/ats-2018-0002\n'},{id:"B50",body:'\nAdebiyi OA, Oboli UT, Adejumo IO, Osinowo OA, Chika CU. Palm oil industry waste as an animal feed and its influence on growth performance of grower pigs. Journal of Animal Science. 2019;97(Supple 3):386, 387. DOI: 10.1093/jas/skz258.769\n'},{id:"B51",body:'\nPourhossein Z, Qotbi AAA, Seidavi A, Laudadio V, Mazzei D, Tufarelli V. Feeding of dried sweet orange (Citrus sinensis) peel on humoral immune response of broiler chickens. International Journal of Recycling of Organic Waste in Agriculture. 2019;8:361-367. DOI: 10.1007/s40093-019-0272-8\n'},{id:"B52",body:'\nOluremi OIA, Ebe AI, Ngi J, Aku EO. Effect of naturally fermented sweet orange (Citrus sinensis) peel meal on its maize replacement value in broiler diet on performance and carcass indices. In: Proc. of 35th Ann. Conf. Nig. Soc. for Anim. Prod. 14-17 March. Nigeria: University of Ibadan; 2010. pp. 449-542\n'},{id:"B53",body:'\nTsai WT, Lin CC, Yeh CW. An analysis of biodiesel fuel from waste edible oil in Taiwan. Renewable and Sustainable Energy Reviews. 2007;11:838-857\n'},{id:"B54",body:'\nHiraoka M, Takeda N, Sakai S, Yasuda A. Highly efficient anaerobic digestion with thermal pretreatment. Water Science and Technology. 1984;17:529-539\n'},{id:"B55",body:'\nCliment M, Ferrer I, Baeza MD, Artola A, Vazquez F, Font X. Effects of thermal and mechanical pre-treatments of secondary sludge on biogas production under thermophilic conditions. Chemical Engineering Journal. 2007;133:335-342\n'},{id:"B56",body:'\nElghali L, Clift R, Sinclair P, Panoutsou C, Bauen A. Developing a sustainability framework for the assessment of bioenergy systems. Energy Policy. 2007;35(12):6075-6083\n'},{id:"B57",body:'\nWismeijer R, Kwant KW, Lammers EA, Novem S, Project Group. A framework for sustainable biomass. Schriftenreihezu Nachhaltigkeit und CSR. 2007;1\n'},{id:"B58",body:'\nNguyen TL, Gheewala SH, Sagisaka M. Greenhouse gas savings potential of sugar cane bio-energy systems. Journal of Cleaner Production. 2010;18(5):412-418\n'},{id:"B59",body:'\nDaoutidis P, Marvin WA, Rangarajan S, Torres AI. Engineering biomass conversion processes: A systems perspective. AICHE Journal. 2013;59(1):3-18\n'},{id:"B60",body:'\nEngling G, He J, Betha R, Balasubramanian R. Assessing the regional impact of Indonesian biomass burning emissions based on organic molecular tracers and chemical mass balance modeling. Atmospheric Chemistry and Physics. 2014;14(15):8043-8054\n'},{id:"B61",body:'\nExley C. Silicon in life: A bioinorganic solution to bioorganic essentiality. Journal of Inorganic Biochemistry. 1998;69:139-144\n'},{id:"B62",body:'\nSjöberg S. Silica in aqueous environments. Journal of Non-Crystalline Solids. 1996;196:51-57\n'},{id:"B63",body:'\nKlein C. Rocks, minerals, and a dusty world. In: Guthrie GD Jr, Mossman BT, editors. Reviews in Mineralogy Vol. 28. Health Effects of Mineral Dust, Mineralogical Society of America. Washington DC: Bookcrafters Inc; 1993. p. 8\n'},{id:"B64",body:'\nMartin KR. The chemistry of silica and its potential health benefits. The Journal of Nutrition, Health & Aging. 2007;11:94-97\n'},{id:"B65",body:'\nMartin KR. Dietary silicon: Is biofortification essential? J Nutr and Food Sci Forecast. 2018;1:1006\n'},{id:"B66",body:'\nNakanishi L, Bombonatti B, Muller LS, Villa RT, Velasco MV, Bedin V, et al. Oral supplementation of orthosilicic acid and its impact on hair quality. Medicina Cutánea Ibero-Latino-Americana. 2017;45:29-35\n'},{id:"B67",body:'\nJugdaohsingh R, Anderson SH, Tucker KL, Elliott H, Kiel DP, Thompson RP, et al. Dietary silicon intake and absorption. The American Journal of Clinical Nutrition. 2002;75:887-893\n'},{id:"B68",body:'\nPopplewell JF, King SJ, Day JP, Ackrill P, Fifield LK, Cresswell RG, et al. Kinetics of uptake and elimination of silicic acid by a human subject: A novel application of 32Si and accelerator mass spectrometry. Journal of Inorganic Biochemistry. 1998;69:177-180\n'},{id:"B69",body:'\nJugdaohsingh R. Silicon and bone health. The Journal of Nutrition, Health & Aging. 2007;11:99-110\n'},{id:"B70",body:'\nChen F, Cole P, Wen L, Mi Z, Trapido EJ. Estimates of trace element intakes Chinese farmers. The Journal of Nutrition. 1994;124:196-201\n'},{id:"B71",body:'\nAnderson JJ. Plant-based diets and bone health: Nutritional implications. The American Journal of Clinical Nutrition. 1999;70:539S-542S\n'},{id:"B72",body:'\nD’Imperio M, Brunetti G, Gigante I, Serio F, Santamaria P, Cardinali A, et al. Integrated in vitro approaches to assess the bioaccessibility and bioavailability of silicon-biofortified leafy vegetables and preliminary effects on bone. In Vitro Cellular & Developmental Biology. Animal. 2017;53:217-224\n'},{id:"B73",body:'\nSripanyakorn S, Jugdaohsingh R, Thompson RPH, Powell JJ. Dietary silicon and bone health. Nutrition Bulletin. 2005;30:222-230\n'},{id:"B74",body:'\nKalapathy U, Proctor A, Shultz J. An improved method for production of silica from rice hull ash. Bioresource Technology;85(3):285-289\n'},{id:"B75",body:'\nGu S, Zhou J, Luo Z, Wang Q , Ni M. A detailed study of the effects of pyrolysis temperature and feedstock particle size on the preparation of nanosilica from rice husk. Industrial Crops and Products. 2013;50:540-549\n'},{id:"B76",body:'\nShim J, Velmurugan P, Oh BT. Extraction and physical characterization of amorphous silica made from corn cob ash at variable pH conditions via sol gel processing. Journal of Industrial and Engineering Chemistry. 2015;30:249-253\n'},{id:"B77",body:'\nUsman AM, Raji A, Waziri NH, Hassan MA. A study on silica and alumina potential of the savannah bagasse ash. IOSR Journal of Mechanical and Civil Engineering. 2014;11(3):48-52\n'},{id:"B78",body:'\nVaibhav V, Vijayalakshmi U, Roopan SM. Agricultural waste as a source for the production of silica nanoparticles. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2015;139:515-520\n'},{id:"B79",body:'\nYuvakkumar R, Elango V, Rajendran V, Kannan N. High-purity nano silica powder from rice husk using a simple chemical method. Journal of Experimental Nanoscience. 2014;9(3):272-281\n'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Isaac Oluseun Adejumo",address:"smogisaac@gmail.com",affiliation:'
Department of Animal Science, Federal University, Nigeria
Department of Animal Science, University of Ibadan, Nigeria
'}],corrections:null},book:{id:"9873",type:"book",title:"Strategies of Sustainable Solid Waste Management",subtitle:null,fullTitle:"Strategies of Sustainable Solid Waste Management",slug:"strategies-of-sustainable-solid-waste-management",publishedDate:"April 21st 2021",bookSignature:"Hosam M. Saleh",coverURL:"https://cdn.intechopen.com/books/images_new/9873.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83962-560-2",printIsbn:"978-1-83962-559-6",pdfIsbn:"978-1-83962-561-9",isAvailableForWebshopOrdering:!0,editors:[{id:"144691",title:"Prof.",name:"Hosam",middleName:null,surname:"Saleh",slug:"hosam-saleh",fullName:"Hosam Saleh"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},profile:{item:{id:"416612",title:"Dr.",name:"Tsholofelo",middleName:null,surname:"Lori",email:"tshololori@gmail.com",fullName:"Tsholofelo Lori",slug:"tsholofelo-lori",position:null,biography:null,institutionString:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",totalCites:0,totalChapterViews:"0",outsideEditionCount:0,totalAuthoredChapters:"1",totalEditedBooks:"0",personalWebsiteURL:null,twitterURL:null,linkedinURL:null,institution:null},booksEdited:[],chaptersAuthored:[{id:"78776",title:"Use of Phytosociology and Remote Sensing to Classify and Map the Vegetation in Protected Areas, Botswana",slug:"use-of-phytosociology-and-remote-sensing-to-classify-and-map-the-vegetation-in-protected-areas-botsw",abstract:"In a natural environment, the vegetation is organized into different plant communities. The vegetation maps produced through phytosociological and remote sensing techniques can be used in the conservation, management, and monitoring of wildlife habitats in protected areas. A desk study was conducted to review studies conducted by various peer-reviewed researchers that used phytosociology and remote sensing methods to classify and map the vegetation in Botswana’s protected areas from 2000 to 2021. Seven studies were carried out in the last two decades, and four out of these studies were conducted in Northern Botswana. Even though a variety of satellite imagery was used, Landsat was the most commonly used. Maximum-likelihood supervised classification and random forest were the most common classification methods used to classify and map the vegetation. Vegetation maps are crucial in knowing which plant species occur in which protected areas, and they are used to manage effectively the vegetation in protected areas. It is important to incorporate phytosociology and remote sensing technology with the management of protected areas to conserve effectively and monitor the vegetation in these areas.",signatures:"Tsholofelo Lori",authors:[{id:"416612",title:"Dr.",name:"Tsholofelo",surname:"Lori",fullName:"Tsholofelo Lori",slug:"tsholofelo-lori",email:"tshololori@gmail.com"}],book:{id:"10844",title:"Protected Area Management",slug:"protected-area-management-recent-advances",productType:{id:"1",title:"Edited Volume"}}}],collaborators:[{id:"416226",title:"Ph.D. Student",name:"Adelakun",surname:"Kehinde Moruff",slug:"adelakun-kehinde-moruff",fullName:"Adelakun Kehinde Moruff",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"416568",title:"Associate Prof.",name:"Binh",surname:"V. Ngo",slug:"binh-v.-ngo",fullName:"Binh V. Ngo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/416568/images/system/416568.jpg",biography:"BINH V. NGO is an Associate Professor of Biology and a senior lecturer at the College of Education, Hue University, Vietnam, where he has taught Zoology, Ecology, and Animal Behavior over the last 6 y. He received his Ph.D. in Zoology from National Cheng Kung University, Taiwan (2015). His research focuses primarily on behavioral ecology, bioacoustics, population biology, community ecology, conservation ecology, log-normal distributions, and site occupancy of amphibians and reptiles living in tropical regions.",institutionString:"Hue University",institution:{name:"Hue University",institutionURL:null,country:{name:"Vietnam"}}},{id:"417681",title:"Dr.",name:"Shafiu Kilishi",surname:"Halidu",slug:"shafiu-kilishi-halidu",fullName:"Shafiu Kilishi Halidu",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"417682",title:"Dr.",name:"Azeez Olalekan",surname:"Ibrahim",slug:"azeez-olalekan-ibrahim",fullName:"Azeez Olalekan Ibrahim",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"417683",title:"Dr.",name:"Olorunfemi Boye",surname:"Oyediran",slug:"olorunfemi-boye-oyediran",fullName:"Olorunfemi Boye Oyediran",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"417926",title:"Prof.",name:"Jean-Eudes",surname:"BEURET",slug:"jean-eudes-beuret",fullName:"Jean-Eudes BEURET",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"417931",title:"Dr.",name:"Anne",surname:"Cadoret",slug:"anne-cadoret",fullName:"Anne Cadoret",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Aix-Marseille University",institutionURL:null,country:{name:"France"}}},{id:"418786",title:"Dr.Ing.",name:"Mirjam",surname:"de Koning",slug:"mirjam-de-koning",fullName:"Mirjam de Koning",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"424027",title:"Dr.",name:"Oliver",surname:"Avramoski",slug:"oliver-avramoski",fullName:"Oliver Avramoski",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"428625",title:"Dr.",name:"Ya-Fu",surname:"Lee",slug:"ya-fu-lee",fullName:"Ya-Fu Lee",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null}]},generic:{page:{slug:"attribution-policy",title:"Attribution Policy",intro:"
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",metaTitle:"Attribution Policy",metaDescription:"DEFINITION OF TERMS",metaKeywords:null,canonicalURL:"/page/attribution-policy",contentRaw:'[{"type":"htmlEditorComponent","content":"
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Kim"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7661",title:"Heat and Mass Transfer",subtitle:"Advances in Science and Technology Applications",isOpenForSubmission:!1,hash:"c29b5c2ce24925a935ca52b8344fbb99",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",bookSignature:"Alfredo Iranzo",coverURL:"https://cdn.intechopen.com/books/images_new/7661.jpg",editedByType:"Edited by",editors:[{id:"67352",title:"Dr.",name:"Alfredo",middleName:null,surname:"Iranzo",slug:"alfredo-iranzo",fullName:"Alfredo Iranzo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:2,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"67726",doi:"10.5772/intechopen.86322",title:"CFD Simulation of Heat and Mass Transfer for Climate Control in Greenhouses",slug:"cfd-simulation-of-heat-and-mass-transfer-for-climate-control-in-greenhouses",totalDownloads:1120,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"Greenhouse plant production involves a number of processes such as transpiration, condensation, photosynthesis, and climate control. Such processes, in turn, set off mass and heat transfer phenomena that influence not only the quality and quantity of crop production but also its environmental cost. While these processes have considerably been analyzed in separate, they strongly interact with one another. For instance, increased radiation (mainly thermal infrared) increases temperature, reduces humidity, consequently increases transpiration, and affects CO2 exchange as well as other reaction rates. Computational fluid dynamics (CFD) is a numerical tool with a solid physical basis which allows, through the construction of a computational model, to simulate the fluid flow environment. Heating, ventilation, and condensation have been analyzed in the greenhouse environment with CFD techniques. The current challenge is the interaction of these processes and their impact on the production system. The present work summarizes some CFD investigations carried out in this topic, in order to analyze the processes of heat and mass transfer in a greenhouse for agronomic purposes.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Cruz Ernesto Aguilar Rodriguez and Jorge Flores Velazquez",authors:[{id:"173578",title:"Dr.",name:"Jorge",middleName:null,surname:"Flores-Velazquez",slug:"jorge-flores-velazquez",fullName:"Jorge Flores-Velazquez"}]},{id:"66158",doi:"10.5772/intechopen.84706",title:"Numerical Solution to Two-Dimensional Freezing and Subsequent Defrosting of Logs",slug:"numerical-solution-to-two-dimensional-freezing-and-subsequent-defrosting-of-logs",totalDownloads:620,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"Two-dimensional mutually connected mathematical models have been created, solved, and verified for the transient non-linear heat conduction in logs during their freezing and subsequent defrosting. The models reflect the influence of the internal sources of latent heat of both the free and bound water on the logs’ freezing process and also the impact of the temperature on the fiber saturation point of wood species, with whose participation the current values of the thermo-physical characteristics in each separate volume point of the subjected to freezing and subsequent defrosting logs are computed. The chapter presents solutions of the models with explicit form of the finite-difference method and their validation towards own experimental studies. Results from experimental and simulative investigation of 2D non-stationary temperature distribution in the longitudinal section of beech and pine logs with a diameter of 0.24 m and length of 0.48 m during their many hours freezing in a freezer and subsequent defrosting at room temperature are presented, visualized, and analyzed.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Nencho Deliiski and Natalia Tumbarkova",authors:[{id:"43040",title:"Prof.",name:"Nencho",middleName:"Stanev",surname:"Deliiski",slug:"nencho-deliiski",fullName:"Nencho Deliiski"},{id:"284649",title:"Dr.",name:"Natalia",middleName:"Yordanova",surname:"Tumbarkova",slug:"natalia-tumbarkova",fullName:"Natalia Tumbarkova"}]},{id:"67626",doi:"10.5772/intechopen.86738",title:"The Boundary Element Method for Fluctuating Active Colloids",slug:"the-boundary-element-method-for-fluctuating-active-colloids",totalDownloads:920,totalCrossrefCites:0,totalDimensionsCites:2,abstract:"The boundary element method (BEM) is a computational method particularly suited to solution of linear partial differential equations (PDEs), including the Laplace and Stokes equations, in complex geometries. The PDEs are formulated as boundary integral equations over bounding surfaces, which can be discretized for numerical solution. This manuscript reviews application of the BEM for simulation of the dynamics of “active” colloids that can self-propel through liquid solution. We introduce basic concepts and model equations for both catalytically active colloids and the “squirmer” model of a ciliated biological microswimmer. We review the foundations of the BEM for both the Laplace and Stokes equations, including the application to confined geometries, and the extension of the method to include thermal fluctuations of the colloid. Finally, we discuss recent and potential applications to research problems concerning active colloids. The aim of this review is to facilitate development and adoption of boundary element models that capture the interplay of deterministic and stochastic effects in the dynamics of active colloids.",book:{id:"8416",slug:"non-equilibrium-particle-dynamics",title:"Non-Equilibrium Particle Dynamics",fullTitle:"Non-Equilibrium Particle Dynamics"},signatures:"William E. Uspal",authors:[{id:"279308",title:"Prof.",name:"William",middleName:null,surname:"Uspal",slug:"william-uspal",fullName:"William Uspal"}]},{id:"66487",doi:"10.5772/intechopen.85735",title:"Mean Aspects Controlling Supercritical CO2 Precipitation Processes",slug:"mean-aspects-controlling-supercritical-co-sub-2-sub-precipitation-processes",totalDownloads:736,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"The use of supercritical CO2 is an excellent alternative in extraction, particle precipitation, impregnation and reaction processes due to its special properties. Solubility of the compound in supercritical CO2 drives the precipitation process in different ways. In supercritical antisolvent process, mass and heat transfers, phase equilibria, nucleation, and growth of the compound to be precipitated are the main phenomena that should be taken into account. Mass transfer conditions the morphology and particle size of the final product. This transfer could be tuned altering operating conditions. Heat transfer in non-isothermal process influences on mixing step the size of generated microparticles. In rapid expansion of supercritical solution, phenomena as the phase change from supercritical to a CO2 gas flow, rapid mass transfer and crystallization of the compound, and expansion jet define the morphology and size of the final product. These phenomena a priori could be modulated tuning a large number of operating parameters through the experiments, but the correlations and modeling of these processes are necessary to clarify the relative importance of each one. Moreover, particle agglomeration in the expansion jet and CO2 condensation are determinant phenomena which should be avoided in order to conserve fine particles in the final product.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Antonio Montes, Clara Pereyra and Enrique J. Martínez de la Ossa",authors:[{id:"55991",title:"Mr.",name:"Antonio",middleName:null,surname:"Montes",slug:"antonio-montes",fullName:"Antonio Montes"},{id:"55992",title:"Dr.",name:"Clara",middleName:null,surname:"Pereyra",slug:"clara-pereyra",fullName:"Clara Pereyra"},{id:"55993",title:"Dr.",name:"Enrique",middleName:null,surname:"Martinez De La Ossa",slug:"enrique-martinez-de-la-ossa",fullName:"Enrique Martinez De La Ossa"}]},{id:"66317",doi:"10.5772/intechopen.85254",title:"Review Heat Transfer of Non-Newtonian Fluids in Agitated Tanks",slug:"review-heat-transfer-of-non-newtonian-fluids-in-agitated-tanks",totalDownloads:1001,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The heating and cooling of non-Newtonian liquids in tanks with mechanical impellers are operations commonly employed as chemical reactors, heat exchangers, distillers, extractors, thinners and decanters. In particular, the design of heat exchangers (jackets, helical coils, spiral coils and vertical tubular baffles) in tanks requires the prior knowledge of the rheology of the liquid for the calculation of the convection coefficients and the Reynolds number, in order to obtain the area thermal exchange. This chapter aimed to present the basic concepts of tanks with agitation, non-Newtonian liquids, hydrodynamics, heat transfer and, finally, with a practical design example for engineers and undergraduate students.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Vitor da Silva Rosa and Deovaldo de Moraes Júnior",authors:[{id:"187128",title:"Ph.D.",name:"Vitor",middleName:null,surname:"Rosa",slug:"vitor-rosa",fullName:"Vitor Rosa"},{id:"188792",title:"Dr.",name:"Deovaldo",middleName:null,surname:"Moraes Júnior",slug:"deovaldo-moraes-junior",fullName:"Deovaldo Moraes Júnior"}]}],mostDownloadedChaptersLast30Days:[{id:"66878",title:"Design of Industrial Falling Film Evaporators",slug:"design-of-industrial-falling-film-evaporators",totalDownloads:1753,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The high performance evaporators are important for process industries such as food, desalination and refineries. The falling film evaporators have many advantages over flooded and vertical tubes that make them best candidate for processes industries application. The heat transfer area is the key parameter in designing of an evaporator and many correlations are available to estimate the size of tube bundle. Unfortunately, most of the correlation is available only for pure water and above 322 K saturation temperatures. Out of these conditions, the areas are designed by the extrapolation of existing correlations. We demonstrated that the actual heat transfer values are 2–3-fold higher at lower temperature and hence simple extrapolated estimation leads to inefficient and high capital cost design. We proposed an accurate heat transfer correlation for falling film evaporators that can capture both, low temperature evaporation and salt concentration effectively. It is also embedded with unique bubble-assisted evaporation parameter that can be only observed at low temperature and it enhances the heat transfer. The proposed correlation is applicable from 280 to 305 K saturation temperatures and feed water concentration ranges from 35,000 to 95,000 ppm. The uncertainty of measured data is less than 5% and RMS of regressed data is 3.5%. In this chapter, first part summarized the all available correlations and their limitations. In second part, falling film evaporation heat transfer coefficient (FFHTC) is proposed and model is developed. In the last part, experimentation is conducted and FFHTC developed and compared with conventional correlations.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Muhammad Wakil Shahzad, Muhammad Burhan and Kim Choon Ng",authors:[{id:"174208",title:"Dr.",name:"Muhammad Wakil",middleName:null,surname:"Shahzad",slug:"muhammad-wakil-shahzad",fullName:"Muhammad Wakil Shahzad"},{id:"249811",title:"Dr.",name:"Muhammad",middleName:null,surname:"Burhan",slug:"muhammad-burhan",fullName:"Muhammad Burhan"},{id:"254696",title:"Prof.",name:"Kim Choon",middleName:null,surname:"Ng",slug:"kim-choon-ng",fullName:"Kim Choon Ng"}]},{id:"66102",title:"Heat and Mass Transfer of Additive Manufacturing Processes for Metals",slug:"heat-and-mass-transfer-of-additive-manufacturing-processes-for-metals",totalDownloads:1302,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Additive manufacturing (AM), a method in which a part is fabricated layer by layer from a digital design package, provides the potential to produce complex components at reduced cost and time. Many techniques (using many different names) have been developed to accomplish this via melting or solid-state joining. However, to date, only a handful can be used to produce metallic parts that fulfill the requirements of industrial applications. The thermal physics and weld pool behaviors in metal AM process have decisive influence on the deposition quality, the microstructure and service performance of the depositions. Accurate analysis and calculation of thermal processes and weld pool behaviors are of great significance to the metallurgy analysis, stress and deformation analysis, process control and process optimization etc. Numerical modeling is also a necessary way to turn welding from qualitative description and experience-based art into quantitative analysis- and science-based engineering branch. In this chapter, two techniques for producing metal parts are explored, with a focus on the thermal science of metal AM: fluid flow and heat transfer. Selective laser melting (SLM) is the one that is most widely used because it typically has the best resolution. Another is named metal fused-coated additive manufacturing (MFCAM) that is cost competitive and efficient in producing large and middle-complex components in aerospace applications.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Zhengying Wei and Jun Du",authors:[{id:"47614",title:"Prof.",name:"Zhengying",middleName:null,surname:"Wei",slug:"zhengying-wei",fullName:"Zhengying Wei"},{id:"282052",title:"Dr.",name:"Jun",middleName:null,surname:"Du",slug:"jun-du",fullName:"Jun Du"}]},{id:"66563",title:"Heat and Mass Transfer in Outward Convex Corrugated Tube Heat Exchangers",slug:"heat-and-mass-transfer-in-outward-convex-corrugated-tube-heat-exchangers",totalDownloads:1037,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"Heat and mass transfer in outward convex corrugated tube heat exchangers is of significant importance for the optimization, fabrication, and application of outward convex corrugated tube heat exchangers. This chapter gives a deep investigation of the heat and mass transfer in outward convex corrugated tube heat exchangers. Based on the experimental setup developed, the performances of a novel outward convex corrugated tube heat exchanger are presented. Simulation methods are then used to detail the heat and mass transfer at tube side and shell side of the outward convex corrugated tube heat exchanger, and these include the flow structure, temperature distribution, and turbulence kinetic energy. Heat and mass transfer enhancements of the outward convex corrugated tube heat exchanger are also studied, and they are from tube side, shell side, and overall system aspects. Finally, multi-objective optimization of the outward convex corrugated tube heat exchanger is conducted to obtain the optimal performances through using Response Surface Methodology (RSM) and Non-dominated Sorting Genetic Algorithm (NSGA-II). Main conclusions and future outlook are then briefly stated and summarized. We firmly believe that the contents presented in this chapter can not only enrich the knowledge of heat exchangers but also develop methods for studying heat exchangers.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Huaizhi Han, Bingxi Li, Yaning Zhang, Quan Zhu and Ruitian Yu",authors:[{id:"23828",title:"Dr.",name:"Quan",middleName:null,surname:"Zhu",slug:"quan-zhu",fullName:"Quan Zhu"},{id:"148369",title:"Prof.",name:"Bingxi",middleName:null,surname:"Li",slug:"bingxi-li",fullName:"Bingxi Li"},{id:"196928",title:"Dr.",name:"Yaning",middleName:null,surname:"Zhang",slug:"yaning-zhang",fullName:"Yaning Zhang"},{id:"281875",title:"Prof.",name:"Huaizhi",middleName:null,surname:"Han",slug:"huaizhi-han",fullName:"Huaizhi Han"},{id:"282268",title:"Mr.",name:"Ruitian",middleName:null,surname:"Yu",slug:"ruitian-yu",fullName:"Ruitian Yu"}]},{id:"66317",title:"Review Heat Transfer of Non-Newtonian Fluids in Agitated Tanks",slug:"review-heat-transfer-of-non-newtonian-fluids-in-agitated-tanks",totalDownloads:1001,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The heating and cooling of non-Newtonian liquids in tanks with mechanical impellers are operations commonly employed as chemical reactors, heat exchangers, distillers, extractors, thinners and decanters. In particular, the design of heat exchangers (jackets, helical coils, spiral coils and vertical tubular baffles) in tanks requires the prior knowledge of the rheology of the liquid for the calculation of the convection coefficients and the Reynolds number, in order to obtain the area thermal exchange. This chapter aimed to present the basic concepts of tanks with agitation, non-Newtonian liquids, hydrodynamics, heat transfer and, finally, with a practical design example for engineers and undergraduate students.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Vitor da Silva Rosa and Deovaldo de Moraes Júnior",authors:[{id:"187128",title:"Ph.D.",name:"Vitor",middleName:null,surname:"Rosa",slug:"vitor-rosa",fullName:"Vitor Rosa"},{id:"188792",title:"Dr.",name:"Deovaldo",middleName:null,surname:"Moraes Júnior",slug:"deovaldo-moraes-junior",fullName:"Deovaldo Moraes Júnior"}]},{id:"65692",title:"Advances in Concentrated Solar Power: A Perspective of Heat Transfer",slug:"advances-in-concentrated-solar-power-a-perspective-of-heat-transfer",totalDownloads:1114,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Solar energy has the potential to reduce the dependence on the dwindling supply of fossil fuels through concentrated solar power (CSP) technology. CSP plants utilize solar thermal energy to produce electrical energy based on different thermodynamic power cycles. Solar collectors, reflectors, receivers, thermal fluid, and turbines are the main components of each CSP plant and involve intensive heat transfer at all stages. This chapter illustrates the thermal characteristics of the main components used in CSP technology. In addition, the solar thermal fluid characteristics and its stable operational ranges are discussed in this chapter. Heat capacity, vapor pressure, volume expansion, density and viscosity of the thermal fluid should not differ significantly at different temperatures during various operation stages because these variations can cause failure in the system, which is designed at the fixed material properties. Currently, CSP technology is associated with a higher cost compared to the electricity generated through gas power plants. Many efforts are made to search for sustainable and inexpensive materials to minimize the cost of CSP. One critical issue faced by CSP technology is the intermittent nature of the sun. Modern CSP plants integrate thermal energy storage (TES) unit to smoothen the power production or to shift the production from peak sunshine hours to peak demand hours.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Fadi Alnaimat and Yasir Rashid",authors:[{id:"151722",title:"Dr.",name:"Fadi",middleName:null,surname:"Alnaimat",slug:"fadi-alnaimat",fullName:"Fadi Alnaimat"},{id:"291252",title:"Mr.",name:"Yasir",middleName:null,surname:"Rashid",slug:"yasir-rashid",fullName:"Yasir Rashid"}]}],onlineFirstChaptersFilter:{topicId:"954",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:8,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:286,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:9,numberOfPublishedChapters:101,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"24",title:"Sustainable Development",doi:"10.5772/intechopen.100361",issn:null,scope:"
\r\n\tTransforming our World: the 2030 Agenda for Sustainable Development endorsed by United Nations and 193 Member States, came into effect on Jan 1, 2016, to guide decision making and actions to the year 2030 and beyond. Central to this Agenda are 17 Goals, 169 associated targets and over 230 indicators that are reviewed annually. The vision envisaged in the implementation of the SDGs is centered on the five Ps: People, Planet, Prosperity, Peace and Partnership. This call for renewed focused efforts ensure we have a safe and healthy planet for current and future generations.
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\r\n\tThis Series focuses on covering research and applied research involving the five Ps through the following topics:
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\r\n\t1. Sustainable Economy and Fair Society that relates to SDG 1 on No Poverty, SDG 2 on Zero Hunger, SDG 8 on Decent Work and Economic Growth, SDG 10 on Reduced Inequalities, SDG 12 on Responsible Consumption and Production, and SDG 17 Partnership for the Goals
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\r\n\t2. Health and Wellbeing focusing on SDG 3 on Good Health and Wellbeing and SDG 6 on Clean Water and Sanitation
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\r\n\t3. Inclusivity and Social Equality involving SDG 4 on Quality Education, SDG 5 on Gender Equality, and SDG 16 on Peace, Justice and Strong Institutions
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\r\n\t4. Climate Change and Environmental Sustainability comprising SDG 13 on Climate Action, SDG 14 on Life Below Water, and SDG 15 on Life on Land
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\r\n\t5. Urban Planning and Environmental Management embracing SDG 7 on Affordable Clean Energy, SDG 9 on Industry, Innovation and Infrastructure, and SDG 11 on Sustainable Cities and Communities.
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\r\n\tThe series also seeks to support the use of cross cutting SDGs, as many of the goals listed above, targets and indicators are all interconnected to impact our lives and the decisions we make on a daily basis, making them impossible to tie to a single topic.
",coverUrl:"https://cdn.intechopen.com/series/covers/24.jpg",latestPublicationDate:"April 24th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:0,editor:{id:"262440",title:"Prof.",name:"Usha",middleName:null,surname:"Iyer-Raniga",slug:"usha-iyer-raniga",fullName:"Usha Iyer-Raniga",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRYSXQA4/Profile_Picture_2022-02-28T13:55:36.jpeg",biography:"Usha Iyer-Raniga is a professor in the School of Property and Construction Management at RMIT University. Usha co-leads the One Planet Network’s Sustainable Buildings and Construction Programme (SBC), a United Nations 10 Year Framework of Programmes on Sustainable Consumption and Production (UN 10FYP SCP) aligned with Sustainable Development Goal 12. The work also directly impacts SDG 11 on Sustainable Cities and Communities. She completed her undergraduate degree as an architect before obtaining her Masters degree from Canada and her Doctorate in Australia. Usha has been a keynote speaker as well as an invited speaker at national and international conferences, seminars and workshops. Her teaching experience includes teaching in Asian countries. She has advised Austrade, APEC, national, state and local governments. She serves as a reviewer and a member of the scientific committee for national and international refereed journals and refereed conferences. She is on the editorial board for refereed journals and has worked on Special Issues. Usha has served and continues to serve on the Boards of several not-for-profit organisations and she has also served as panel judge for a number of awards including the Premiers Sustainability Award in Victoria and the International Green Gown Awards. Usha has published over 100 publications, including research and consulting reports. Her publications cover a wide range of scientific and technical research publications that include edited books, book chapters, refereed journals, refereed conference papers and reports for local, state and federal government clients. She has also produced podcasts for various organisations and participated in media interviews. She has received state, national and international funding worth over USD $25 million. Usha has been awarded the Quarterly Franklin Membership by London Journals Press (UK). Her biography has been included in the Marquis Who's Who in the World® 2018, 2016 (33rd Edition), along with approximately 55,000 of the most accomplished men and women from around the world, including luminaries as U.N. Secretary-General Ban Ki-moon. In 2017, Usha was awarded the Marquis Who’s Who Lifetime Achiever Award.",institutionString:null,institution:{name:"RMIT University",institutionURL:null,country:{name:"Australia"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. 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Main aspects of the topic are: Applying bioinformatics in drug discovery and development; Bioinformatics in clinical diagnostics (genetic variants that act as markers for a condition or a disease); Blockchain and Artificial Intelligence/Machine Learning in personalized medicine; Customize disease-prevention strategies in personalized medicine; Big data analysis in personalized medicine; Translating stratification algorithms into clinical practice of personalized medicine.",annualVolume:11403,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",editor:{id:"351533",title:"Dr.",name:"Slawomir",middleName:null,surname:"Wilczynski",fullName:"Slawomir Wilczynski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035U1loQAC/Profile_Picture_1630074514792",institutionString:null,institution:{name:"Medical University of Silesia",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"5886",title:"Dr.",name:"Alexandros",middleName:"T.",surname:"Tzallas",fullName:"Alexandros Tzallas",profilePictureURL:"https://mts.intechopen.com/storage/users/5886/images/system/5886.png",institutionString:"University of Ioannina, Greece & Imperial College London",institution:{name:"University of Ioannina",institutionURL:null,country:{name:"Greece"}}},{id:"257388",title:"Distinguished Prof.",name:"Lulu",middleName:null,surname:"Wang",fullName:"Lulu Wang",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRX6kQAG/Profile_Picture_1630329584194",institutionString:null,institution:{name:"Shenzhen Technology University",institutionURL:null,country:{name:"China"}}},{id:"225387",title:"Prof.",name:"Reda",middleName:"R.",surname:"Gharieb",fullName:"Reda Gharieb",profilePictureURL:"https://mts.intechopen.com/storage/users/225387/images/system/225387.jpg",institutionString:"Assiut University",institution:{name:"Assiut University",institutionURL:null,country:{name:"Egypt"}}}]},{id:"8",title:"Bioinspired Technology and Biomechanics",keywords:"Bioinspired Systems, Biomechanics, Assistive Technology, Rehabilitation",scope:'Bioinspired technologies take advantage of understanding the actual biological system to provide solutions to problems in several areas. Recently, bioinspired systems have been successfully employing biomechanics to develop and improve assistive technology and rehabilitation devices. The research topic "Bioinspired Technology and Biomechanics" welcomes studies reporting recent advances in bioinspired technologies that contribute to individuals\' health, inclusion, and rehabilitation. Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',annualVolume:11404,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"49517",title:"Prof.",name:"Hitoshi",middleName:null,surname:"Tsunashima",fullName:"Hitoshi Tsunashima",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTP4QAO/Profile_Picture_1625819726528",institutionString:null,institution:{name:"Nihon University",institutionURL:null,country:{name:"Japan"}}},{id:"425354",title:"Dr.",name:"Marcus",middleName:"Fraga",surname:"Vieira",fullName:"Marcus Vieira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003BJSgIQAX/Profile_Picture_1627904687309",institutionString:null,institution:{name:"Universidade Federal de Goiás",institutionURL:null,country:{name:"Brazil"}}},{id:"196746",title:"Dr.",name:"Ramana",middleName:null,surname:"Vinjamuri",fullName:"Ramana Vinjamuri",profilePictureURL:"https://mts.intechopen.com/storage/users/196746/images/system/196746.jpeg",institutionString:"University of Maryland, Baltimore County",institution:{name:"University of Maryland, Baltimore County",institutionURL:null,country:{name:"United States of America"}}}]},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering",scope:"The Biotechnology - Biosensors, Biomaterials and Tissue Engineering topic within the Biomedical Engineering Series aims to rapidly publish contributions on all aspects of biotechnology, biosensors, biomaterial and tissue engineering. We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. 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