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Christian Palavecino

Central University of Chile Chile

Christian E. Palavecino earned his Medical Technologist degree at the Universidad Austral de Chile in 2001. He then earned his M.Sc. and Ph.D. in Microbiology and Molecular Biology from the Universidad Austral de Chile. Dr. Palavecino was awarded an Alban office grant to develop his Ph.D. thesis at the Queen Mary University of London to investigate the molecular basis of Mycobacterium-host interactions. After his Ph.D. degree, he was a postdoctoral fellow at the School of Biological Sciences at the Pontificia Universidad Católica de Chile, focusing his research on vaccine development to prevent human metapneumovirus infection. He is currently an assistant professor at the Facultad de Ciencias de la Salud at the Universidad Central de Chile, working to develop complementary antimicrobial therapy against multidrug-resistant bacteria. His research focuses on developing and evaluating photosensitizing molecules used in photodynamic therapy to inhibit bacterial growth.

1chapters authored

Chapters authored

Photodynamic Treatment of Staphylococcus aureus Infections

By Christian Erick Palavecino, Camila Pérez and Tania Zuñiga

Introduction: Staphylococcus aureus is a Gram-positive coconut that causes various life-threatening infections and, in turn, represents a major producer of healthcare-associated infections. This pathogen is highly resistant to antibiotics, which has made it difficult to eradicate in recent decades. Photodynamic therapy is a promising approach to address the notable shortage of antibiotic options against multidrug-resistant Staphylococcus aureus. This therapy combines the use of a photosensitizing agent, light, and oxygen to eradicate pathogenic microorganisms. The purpose of this study is to provide relevant bibliographic information about the application of photodynamic therapy as an alternative antimicrobial therapy for Staphylococcus aureus infections. Methods: This review was achieved through a bibliographic search in various databases and the analysis of relevant publications on the subject. Results: A large body of evidence demonstrates the efficacy of photodynamic therapy in eliminating biofilm- or biofilm-producing strains of Staphylococcus aureus, as well as antibiotic-resistant strains. Conclusion: We conclude that photodynamic therapy against Staphylococcus aureus is a recommended antibacterial therapy that may complement antibiotic treatment.

Part of the book: Photodynamic Therapy

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