Results of
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
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Lignin is composed of alkyl-aryl ether polymers and is found in the cell walls of trees and plants. It is known as the second most naturally abundant biopolymer. The book will focus on the application of lignin in various materials, its synthesis and characterizations, and its development prospects followed by degradation methodologies. In addition to that, it will also emphasize the strategies to prepare nano- and microparticles of lignin by various means, as well as their chemical modification to obtain desired properties. It will also include the industrial aspects of lignin, lignin derivatives, their configuration, and their significant role in thermosetting, thermoplastic materials. In addition, the book welcomes contributions on the technical and economical potential of lignin in generating green bio-fuel and fine chemicals which will or can be used as an energy source for various industrial plants.
",isbn:"978-1-83968-546-0",printIsbn:"978-1-83968-545-3",pdfIsbn:"978-1-83968-861-4",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"4c3ccf3ce961d9c60aeb9774034eeb87",bookSignature:"Associate Prof. Arpit Sand and Dr. Jaya Tuteja",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11902.jpg",keywords:"Biofuel, Esters, Ethers, Adhesives, Lignin, Structural Features, Physicochemical Properties, Degradation Techniques, Biosynthesis, Biodegradation, Kraft Lignin, Qualitative Analysis",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 14th 2022",dateEndSecondStepPublish:"June 23rd 2022",dateEndThirdStepPublish:"August 22nd 2022",dateEndFourthStepPublish:"November 10th 2022",dateEndFifthStepPublish:"January 9th 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"2 months",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Dr. Sand, associate professor of Chemistry, was a postdoctoral fellow at Gwangju Institute of Science & Technology, Korea, and at Karolinska Institutet, Sweden. With a keen interest in polymer synthesis, Dr. Sand is an editorial board member for Polymer Synthesis Journal by Cambridge Scholars Publishing UK and Journal of Polymer Science.",coeditorOneBiosketch:'An enthusiastic, disciplined, well-organized Assistant Professor in Chemistry, Dr. Tuteja earned her Ph.D. degree in Materials Science from the Japan Advanced Institute of Science and Technology (JAIST) in 2015 for which she was awarded an “Excellent Doctorate Student". Her research includes the development and application of heterogeneous catalysts for the effective conversion of biomass to value-added products.',coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"287032",title:"Associate Prof.",name:"Arpit",middleName:null,surname:"Sand",slug:"arpit-sand",fullName:"Arpit Sand",profilePictureURL:"https://mts.intechopen.com/storage/users/287032/images/system/287032.jpg",biography:"Dr. Arpit Sand is currently an associate professor in the Department of Chemistry, Manav Rachna University, Faridabad, India. He received his BSc in Science and MSc in Chemistry from the University of Allahabad, India, in 2004 and 2006, respectively. He received his Ph.D. in Chemistry from the same university in 2010. Dr. Sand is an editorial board member for Polymer Synthesis Journal by Cambridge Scholars Publishing UK and Journal of Polymer Science. He is an academic book editor and a reviewer for international journals including Carbohydrate Polymers, International Journal of Biological Macromolecules, and Fibers and Polymers, among others.\r\nDr. Sand’s previous roles include assistant professor (guest faculty) in the Department of Chemistry, University of Allahabad; research associate at the National Physical Laboratory (NPL) New Delhi; postdoctoral fellow at Gwangju Institute of Science & Technology (GIST), Korea; postdoctoral fellow at Karolinska Institutet, Sweden; junior researcher at the Brno University of Technology, Czech Republic; and researcher at Soongsil University, South Korea.\r\nHe has more than ten years of teaching and research experience. He is also a life member of the Indian Science Congress and Green Chemistry Network center. He has made significant contributions in the modification and characterization of graft copolymers and films decorated with chalcogenide quantum dots to tune the energy bandgap for solar energy harvesting applications. His research interests include polymer synthesis using different polymerization techniques. He has authored more than twenty-four international research articles and review articles in reputed SCI journals.",institutionString:"Manav Rachna University Faridabad",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"1",institution:null}],coeditorOne:{id:"453331",title:"Dr.",name:"Jaya",middleName:null,surname:"Tuteja",slug:"jaya-tuteja",fullName:"Jaya Tuteja",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003NAhktQAD/Profile_Picture_1643970806232",biography:"Dr. Jaya Tuteja is currently working as Assistant Professor, Department of Chemistry, Faculty of Applied Science, Manav Rachna University since January 2018. She earned her Ph.D. degree in Materials Science from Japan Advanced Institute of Science and Technology (JAIST), Japan in 2015 and was awarded as “Excellent Doctorate Student” by JAIST. \r\nShe has published 5 research papers in reputed international journals with a sum of impact factor of >25. She also has 2 patents filed on her name from her Ph.D. research work. One of the articles in ChemSusChem 7 (1), 96-100 has reached a citation of more than 100 and was selected among 25 Most Accessed Articles from ChemSusChem. Her first research article was awarded a BCSJ award article. She also has 1 book chapter in her account.\r\nBefore joining Manav Rachna University, she was working in a chromatography Industry YMC India Ltd. as a Technical and Application Manager. Her research area includes the development, characterization, and application of heterogeneous catalysts for effective conversion of biomass to value-added products, nanoparticles synthesis and nanoparticle-based heterogeneous catalysts, bimetallic nanoparticles, carbohydrate chemistry, and analytical techniques for compound identification.",institutionString:"Manav Rachna University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"0",institution:null},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"8",title:"Chemistry",slug:"chemistry"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"444315",firstName:"Karla",lastName:"Skuliber",middleName:null,title:"Mrs.",imageUrl:"https://mts.intechopen.com/storage/users/444315/images/20013_n.jpg",email:"karla@intechopen.com",biography:"As an Author Service Manager, my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"10776",title:"Cellulose Science and Derivatives",subtitle:null,isOpenForSubmission:!1,hash:"947660259ce1915c3cac58bf7d990424",slug:"cellulose-science-and-derivatives",bookSignature:"Arpit Sand and Sangita Banga",coverURL:"https://cdn.intechopen.com/books/images_new/10776.jpg",editedByType:"Edited by",editors:[{id:"287032",title:"Associate Prof.",name:"Arpit",surname:"Sand",slug:"arpit-sand",fullName:"Arpit Sand"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. 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Imaging with terahertz (THz) radiation is a research field that has gained a lot of interest and is in the process of moving from research laboratories to commercial applications [1, 2, 3, 4]. As such, the THz research field has grown so much that it has become impossible for a single human to be able to keep track of all developments [4]. Nevertheless, it is possible to outline why there is great interest and potential in THz imaging technology. Most non-conductive materials and non-polar liquids are THz transparent, useful for non-invasive inspection of many multi-component or buried systems, such as paintings [5], electronic circuits [6], space shuttle panels [7] and carbon-fiber composites [8]. Other possibilities are the measurement of picosecond processes in semiconductors [9], quality control of pharmaceutical tablets [10] and non-invasive detection of explosive substances [11]. A plethora of fundamental material resonances, such as phonons, rotations of molecules and precessions of spins, are observable and controllable by THz radiation [12]. Bio-medical applications are highly alluring most notably because the THz photon energies are non-ionizing and high-water sensitivity gives rise to label-free diagnosis of diseases that alter water content, such as cancer [13] and diabetic foot syndrome [14]. There is also the possibility of damaging or repairing DNA with intense THz radiation [15].
With so many possible applications, the reason why THz radiation is barely used outside of laboratories is due to costs of current THz technology. In particular to imaging, the technology is either too expensive, too slow or sacrifices some detection capability (such as picosecond temporal resolution). This is because materials which are suitable for efficient THz detection simply do not exist. This has resulted in THz detector arrays normally working in either narrowbands [16] or needing cryogenic temperatures for sensitive detection [17]. However, microbolometer arrays have very large bandwidths at room temperature operation [18] and when combined with digital holography they can measure both the amplitude and phase of THz radiation [19, 20]. Unfortunately bolometers achieve frequency resolution with a frequency selective source and they do not offer picosecond temporal resolution. This is acceptable for some applications such as detecting concealed weapons, however for applications where time gated detection is used, for example in extracting depths of painting coatings in original art works [5], it becomes unfeasible. An another imaging technique is to project a THz image on an electro-optic crystal then use visible light CCD arrays to spatially map-out the THz field incident onto the crystal [21, 22]. This does not sacrifice the temporal resolution offered time-domain THz spectrometers, however this needs a regen-amplified Ti:Sapphire laser which makes the whole system big and expensive and has prevented the widespread adoption of this technology despite its capabilities. These imaging techniques are all far-field, apart from [21], meaning that they fail to see detail below
The aforementioned imaging approaches are the standard imaging techniques, relying on a detector array or raster scanning, however there is another alternative. Namely, using a spatially modulated light beam and a single-pixel detector to obtain an image [30]. Approaches based on this technique are commonly called
Single-pixel imaging theory concerns itself with obtaining an image of a scene using a detector that can only measure the total amplitude emanating from the scene. The simplest idea is to raster scan an aperture across the field-of-view, building the image pixel by pixel. However, as the aperture is made smaller and smaller, the signal reaching our detector is reduced. We could increase the light incident onto our detector and overcome detector-noise by simultaneously scanning more apertures during each measurement, an idea that originates with Yates in 1935 [32]. In Figure 1(a) we show the main principle of this idea; we have a light beam that is spatially modulated which propagates through an object and onto a detector with no spatial resolution. It is of the utmost importance that in each measurement we know which apertures were open and which were closed. Without this information we could never reconstruct an image of the object. Each measurement is the dot product of the spatial encoding mask and the transmission function of the object, which is mathematically expressed as
(a) Imaging with a single-element detector. An encoding mask spatially encodes a beam of radiation, then the beam passes through an object and onto the single-element detector. (b) Spatial encoding masks, where the first, second, third and fourth coloumns were constructed from Sylvester Hadamard, cyclic Hadamard, random and Fourier matrices respectively. The green triangle in the cyclic mask is there as a visual guide. (c) 2D image transform examples. Figure (a) was extracted from reference [
where
where the rows of matrix
The Sylvester-Hadamard matrices are binary, meaning that they are easily implemented, specifically with digital micromirror devices which are relatively cheap and have switch rates upto 20 kHz. The reconstruction technique can also be efficiently calculated by just doing the Fast Hadamard-Walsh transform, meaning one does not need to store
The Cyclic-Hadamard matrices, also known as Paley Type I and type II Hadamard matrices as they were first discovered by Paley in 1933 [36], are orthogonal and circulant matrices made of 1 s and -1 s. This means they have large noise robustness, easy binary implementation and they are constructed by having one vector,
Random masks constructed from Bernoulli matrices, or Gaussian random matrices, can also be made from 1 s and -1 s making for easy implementation using binary spatial light modulators. However, these matrices are not directly invertible and using a pseudo-inverse can create stability problems. Therefore convex minimization algorithms are usually used for image reconstruction [30, 31]. The main benefit of this masking approach is that is can be used for undersampling which can greatly reduce the total measurement time at the expense of complicated calculations. References [37, 38] were the first theoretical investigation and one can obtain their reconstruction scripts from reference [39], although reference [40] also freely provides their MATLAB scripts for another minimization algorithm called TVAL3 [41]. These algorithms can be slow, hence a mention needs to be given to reference [42] where Kowarlz et al. creates a pseudo-inverse matrix via Fourier-domain regularization that is able to recover images of quality similar to the slow minimazation algorithms, however with faster calculations based on matrix multiplication methods. Note, they also provide their MATLAB and Python scripts freely on github [43].
Fourier masks are those derived from the Fourier matrix. However, as this is just linear algebra representation of the Fourier transform and we are measuring real images (without imaginary numbers), then we do not need to measure the negative Fourier frequencies as they are just the complex conjugate of their positive frequency counterpart. The Fourier matrix is also orthogonal meaning it has noise robustness equal to the Hadamard matrices as well efficient image reconstruction algorithms, simply the Fast Fourier Transform. These masks, however, are not binary but require grayscale values which limits their deployability. Binary spatial modulators can accomplish this either by temporal dithering, at the expense of slower switch-rates, or by spatial dithering, which creates some quantization errors [34]. Nevertheless, these masks benefit from extensive literature based on the Fourier Transform and various image compression algorithms that can be reversed for image-undersampling procedures.
In this single-pixel imaging modality, the most crucial part is to create a spatially modulated beam. In this respect for the THz regime there are four main methods that can be employed; by creating a physical mechanical mask, by changing the electrical conductivity of a material via the injection/depletion of charge carriers, by controlling the refractive index of liquid crystal cells and by creating a spatially varied beam directly at the THz generation stage.
Creating a physical mask to modulate THz radiation has the great advantage that this is the easiest in terms of manufacturing with great modulation depth,
There is another modulation technique that falls in this mechanical category. Namely, mirror arrays where each mirror can be individually addressed. Such arrays already exist for the visible light regime in the form of digital micromirror arrays (DMD). However, DMD mirrors are with dimensions around 10
Schematic of a single pixel of the THz-SLM for normally incident terahertz waves. The pixel is composed of mirrors that are arranged in 4 rows and 8 columns. (a) OFF-state for a bias voltage of 0 V. all mirrors are inclined and incident terahertz radiation (red) is diffracted away (blue) from the transceiver. (b) ON-state for a bias voltage of 37 V. all mirrors are pulled down to the substrate and incident terahertz radiation (red) is reflected (blue) into the transceiver. (c) Schematic cross-sectional view of an unreleased mirror. The base of the mirror adheres to the parylene C, while the part to be released sits on the poly-Si. (d) Schematic cross-sectional view of a released mirror. The base of the mirror adheres to the parylene C, while the released part is inclined due to residual stress in the Cr-Cu-Cr mirror material. (e) Modulation contrast of the THz-SLM. The contrast exceeds a value of 0.5 for a working range from 0.97 THz to 2.28 THz with a maximum contrast of 0.87 at 1.38 THz. (f) Linear dependence of the detected modulated electric field on the number of switched-ON rows in the THz-SLM. (g) Linear dependence of the detected modulated electric field on the number of switched-ON columns in the THz-SLM. Figure reprinted from reference [
The main principle with this THz modulation technique is based upon the Drude model dielectric function [48, 49].
where
Optical based spatial THz-light modulators are currently the best in terms of achieved switch-rate, operational frequency and ease of implementation. Their switch-rate and operational frequencies are both similar to the electrical modulators in that they also rely on modifying the charge carrier density in some material. However, as they use optical light to achieve this, their experimental implementation is very different and due to the current state of visible-light SLMs they are much easier to be implemented. One starts by patterning a visible light beam and then projecting this spatial pattern onto a semiconductor, thereby creating areas that experience large optical excitation and other areas which are left in their ground state. This in turn creates a spatially varying conductivity/absorption profile on the surface of the semiconductor, and thus if a THz beam passes through this surface then the inverse spatial pattern from the visible-light beam is imparted onto the THz beam. The optical excitation can come in two forms, pulsed and continuous wave. For both cases, the carrier concentration is described by
for carrier generation rate
For continuous wave excitation one needs to consider the photo-carrier generation, recombination and diffusion dynamics within the semiconductor. The steady-state equilibrium carrier concentration within the semiconductor is given by [48].
where
(a) Carrier density (in arbitrary units) for different carrier lifetimes, shown by the colored numbers in ms, as we switch a continuous wave source on and off. (b) Illustration of imaging setup: Using a digital micromirror device and a lens, a pump pulse is spatially structured and projected onto a silicon wafer. This spatially modulates a coincident THz pulse. This THz pulse then passes through an object and is measured on a single-element THz detector. Inset is an optical image of a resolution test target (cartwheel) manufactured from gold on a 6
For pulsed optical-excitation probed by a synchronous THz pulse, Eq. (5) changes because the THz pulse can travel through the spatially photopumped region a few picoseconds after photoexcitation and for
Electrical based modulators are likely to be the long-term future solution for spatial THz modulators because they have very little fundamental limitations. Namely, the maximum switch-rates are limited by the carrier recombination rates meaning they can potentially achieve megahertz switch rates, provided the RC constants of the devices are taken into account, especially with electrically tunable materials such as graphene [58, 59]. Their size is determined by photolithographic manufacturing technologies, which is already orders of magnitudes smaller than the THz wavelengths meaning that pixel sizes can be highly subwavelength. In fact, sometimes THz modulation structures can be too large for some commercial photolithographic systems. They are fully self-contained and compact, which is their main advantage over the optical based modulators (see
One of the first demonstrations of this modulation technique was by Kleine-Ostmann et al. in 2004 [60] where they electronically depleted carriers from a GaAs/AlGaAs interface, achieving about 3% modulation across a broadband frequency range of 0.1 to 2 THz. Since then there have been numerous attempts at improving the modulation depth, see references [61, 62] for recent reviews. These efforts have included enhancing the interaction between the THz wave and the charge carrier regions by metamaterial structures [63, 64]. Others have recently used graphene as the modulator [65, 66]. Using metamaterials or Fabry-Perot type resonances to enhance the modulation depth has the trade-off of reducing the working frequencies of the modulator. A further note is that subwavelength grating structures can enhance the THz modulation over a broadband range [58] for the correct THz polarization.
In 2014 C. M. Watts et al. created an electrical based THz-SLM in reference [67], and Figure 4(a) shows their experimental schematic and part (b) shows an image of their SLM. They electrically change the THz absorption of a 2
(a) Schematic of the single-pixel imaging process utilizing an SLM. An image is spatially modulated by the metamaterial and the resulting radiation is sent to the single-pixel detector. (b) Photograph of the SLM (courtesy of K. burke, Boston College media technology services); total active area of the SLM is (4.8 mm
Another innovative approach to single-pixel imaging is to create a spatially patterned beam at the generation step, rather than generate a homogeneous beam that is then spatially modulated, which has the benefit of not needing a THz-SLM. For the terahertz regime, this can be accomplished by three possible ways. First, having an array of photoconductive antennas [70, 71, 72], however this approach suffers from antenna cross-talk and inefficiency problems arising from the small working-area of the antennas whilst occupying a large area. Further, such antennas arrays have only been used as detectors. The second method is to use an electro-optic (EO) crystal that converts visible-light to THz frequencies via non-linear polarization effects [73]. The generation of THz radiation is localized to where the visible light is, hence projecting a spatially varying light beam will generate a THz-beam with the same spatial features. This idea was implemented by references [74, 75] where they used a used a SLM to pattern an 800 nm femtosecond pulse and project that onto a ZnTe crystal. The third method is similar to the second one, with the difference being the use of a spintronic THz emitter instead of an electro-optic crystal. Here the inverse spin Hall effect is used to generate an ultrafast current transient that generates the THz radiation [76, 77, 78]. The spatial patterning is again done by a visible-light SLM since the THz generation is again localized to areas where the optical-pump was shined upon. This was demonstrated by Chen et al. in reference [79].
The similarities between the spintronic and electro-optic crystal approaches are that they both require femtosecond pulses with mJ/cm
Figure 5(a) shows the experimental setup of reference [79] which uses the spintronic emitter array approach. Note that the EO crystal approach is identical in that you only have to replace the spintronic emitter with the EO crystal and remove the magnetic field, then place the object as close as possible to the emitter array. One should note that the use of the second DMD in Figure 5(a) is only to correct the phase front induced by first DMD, which can also be achieved by the technique shown in the supplementary information of reference [82]. The spintronic emitter is nanometer thick hence Chen et al. was able to resolve metallic lines 6
(a) Schematic of the GHOSTEAM system. The spintronic THz emitter array (STEA) is excited by two-DMD-encoded fs laser pulses and generates spatially coded THz pulses. An object “CAEP” was placed in the near-field region (
Liquid crystal modulators work by the re-orientating the material molecules under an applied voltage. As the molecules are oblong, this changes the refractive index that an electro-magnetic wave experiences. Therefore these devices are great for phase modulation giving the greatest freedom in the values that the sampling matrix can take. In other words, they can theoretically project a Fourier matrix that has grayscale complex-values. Note that complex valued masks can be used in conjunction with an intensity only detector to obtain an image that has phase and amplitude information [83]. A liquid crystal based SLM for THz was computationally studied [84]. However, the re-orientation of the molecules is a slow process, and in the visible light regime liquid crystal displays are typically limited to below 100 Hz switch rates. Due to the longer THz wavelengths, thicker layers of liquid crystals are needed resulting in even slower switch rates. For this reason, liquid crystal spatial modulators for THz radiation have been limited mostly to applications where slow switching speeds are acceptable such as dynamically controllable lenses [85, 86], absorption [87] or polarization control [88].
The first demonstration of a single-pixel THz camera that uses a multi-pixel modulation approach3 was in 2008 by Chan et al. [89]. Therein the authors showed amplitude and phase imaging was possible. Since Chan showed single-pixel THz imaging with metallic masks [89], most publications up until now have focused on improving the implementation by showing proof-of-concept modulation/generation techniques as opposed to potential applications. Shortly after in 2009 spectroscopic imaging was demonstrated [90]. The next experiment was in 2012 by Shen et al. [46] where they used a spinning disc with random masks, but it should be noted that their experiment used an infrared and a THz source whilst using the same SLM. The first demonstration of an optical based SLM was by Shrekenhamer et al. in 2013 [49]. The same group then published an electrical based SLM for single-pixel THz imaging in 2014 [67]. The next developments showed in 2016 that such imaging systems can detect a sub-wavelength fissure (8
The potential applications and capabilities of single-pixel THz cameras are directly determined by the THz source and detector, rather than the technique used to impart a spatial pattern in a beam of THz radiation. As such, it is unlikely for there to be a single-solution for all practical applications. Therefore, it is valuable to discuss where each of the techniques in
The metallic/physical based masks, employed in
Modifying the Drude plasma frequency of a semiconductor via injection/depletion of charge carriers has great potential for compact integration of the entire imaging system, as long as electrical gating is used as it negates the need for an extra pump-laser. The drawback is that to ensure modulation depth over a large frequency range the Drude plasma frequency has to be sufficiently modified. For example, after photoexcitation of silicon if
Direct generation of a spatially varying THz beam,
Although the first experimental implementations of single-pixel cameras can be traced back to 1976 [97], such imaging approaches were not widely studied or implemented in the commercial world. The reason is that the serial measurement of such ideas can not compete with parallel data acquisition of imaging arrays. Further, compressed sensing techniques began gaining mainstream attention in 2006 after two publications [37, 38]. This coincides with the development of visible light spatial modulators thereby allowing the implementation of the ideas in references [37, 38]. Whilst inherently slower than imaging arrays, these single-pixel cameras are much more robust and easier to implement in areas where imaging array technology is unavailable. In particular, the terahertz frequency regime.
This book chapter began by outlining the current state of THz cameras. Then it discusses the background theory of single-pixel imaging techniques. Most of the chapter was dedicated to discussing the current state of spatial THz-light modulators for use in single-pixel THz imaging in
The most advanced THz-SLM at present are those based on optical excitation of semiconductors,
Ultimately, the development of single-pixel THz cameras is likely to proceed with optical modulators being used in university laboratories to optimize the algorithms and methodologies used in image recovery as well as synchronization of all the equipment. Simultaneously there will be an effort to develop electrical based array modulators that have fast-switch rates and large modulation depth over a broadband frequency range. Then the miniaturization of such modulator arrays will start and it is likely that at this point such commercially available THz-SLMs will become available from new specialized start-up companies. Spatially-generated THz beams will likely remain only in laboratories for fundamental studies of different systems, but are unlikely to be used for industrial and commercial applications mostly due to the requirement of pump powers of
This work was partially supported by the Research Grants Council of Hong Kong (project numbers 14206717 and 14201415), The Hong Kong Innovation and Technology Fund (project number ITS/371/16), The Engineering and Physical Sciences Research Council (grant number EP/S021442/1), and the Royal Society Wolfson Merit Award (EPM).
The authors declare no conflict of interest.
Atomic force microscope
Printed Circuit Board
Field-programmable gate array
Spatial light modulator
Terahertz
Electro-optic
Signa-to-noise ratio
Digital micromirror device
Vanadium Dioxide
Charge Coupled device
Technological innovations and work process automation play a key role in meeting the increased demands that organizations face in today’s competitive and fast-changing market [1]. To become and remain efficient, automation and robotics offer many solutions for the potential optimization of work processes. Robotic Process Automation (RPA) is currently one of the most used tools in business process automation that stimulates higher organizational productivity [2]. RPA is a software robot that uses the interface of an already present computer system and mimics the actions of a human employee. RPA can automate work processes that are administrative, well-structured, and repetitive of nature [3, 4, 5]. Typical tasks that can be done by RPA entail, for example, processing incoming emails and orders, transferring data from one digital system to another, and searching for and communicating with potential new hires. Organizations greatly benefit from the implementation of RPA, mainly due to increased process speed and production growth, as well as error reduction [6].
However, although there are many advantages to the commissioning of RPA, it is estimated that between 30 and 50% of all RPA implementations fail [7]. This relatively high number of unsuccessful RPA implementations is in line with the general notion that digital transitions often do not result in desired outcomes, such as enhanced productivity and efficiency. A potential explanation for failing technological implementations is the lack of consideration for the employees who have to work with a new technology [8]. With this study we aim to gain more insight in this human-technology interaction [9] by investigating to what extent the implementation of an RPA technology impacts work characteristics and employee well-being.
In-depth knowledge on the consequences of digital transitions for the work characteristics and employee well-being is increasingly important, because both are to a large extent predictive of overall employee performance and organizational productivity [10, 11]. By studying this issue we contribute to the existing body of knowledge on workplace automation and information systems in two important ways. First, this study aims to address the research gap concerning the impact of workplace automation on individual work experiences. Whereas earlier research has mainly focused on the effects of technological innovations on employment and labor market composition, we argue that more understanding of the relationship between the implementation of an automation system and work characteristics, as well as well-being of those who have to work with these new technologies can contribute to the successful implementation of technological innovations. This can help organizations that want to innovate and invest in better designed jobs, as well as lead to better implementations of new technologies such that sustainable employee performance can be consolidated and organizational efficiency can be achieved. Second, we aim to contribute to the growing body of literature on workplace automation and the application of RPA technology [5, 6, 12, 13]. More specifically, we examine to what extent RPA influences the work experiences of employees and whether RPA technology results in the desired outcomes with regard to a decrease in job demands, an increase in job resources, and in turn enhanced employee well-being. In sum, with this research we want to achieve a better understanding of how employees experience working with RPA, so that such an innovation in the future actually contributes to what it is intended for and does not generate negative side effects. In the following sections, we will explain how RPA can influence work characteristics and how these work characteristics are related to employee well-being.
Work process automation changes the way work is performed and perceived by employees. For example, the use of robots that automate heavy manual labor can result in less physically straining job tasks for employees, while at the same time requires them to handle new machinery. Similarly, the use of chatbots can significantly decrease interpersonal interactions at work, but can potentially also result in employees to feel alienated from their original work role. Hence, the introduction of a new technology and workplace automation can have both simultaneously positive and negative influences on employees’ work experiences.
The idea behind RPA technology is that administrative work processes become more streamlined and efficient, so that employees have to spend less time on performing repetitive work tasks [3]. Compared to traditional automation systems (e.g., BPM, CRM) RPA can automate many different work tasks, is easy to implement and use, and does not require modification of existing IT infrastructures [5]. As such, RPA is unique in a sense that it requires minimal human intervention, can be applied to a range of business applications, and is designed such that end users can make changes without the need to possess extensive programming skills. Although RPA does not automate and replace complete jobs, it does substantially change certain tasks and the way jobs are designed [9, 14]. Therefore, the implementation of RPA is likely to change the way employees (perceive their) work and thus can result in better or worse designed jobs, which likely has a profound impact on important outcomes related to employee work experiences and well-being [9].
From a work design perspective, the job demands-resources model states that all work characteristics can be divided into job demands and job resources [15]. Job demands, such as workload, time pressure, and role conflict, refer to all aspects of a job that require continuous cognitive or emotional effort and are related to physiological and/or psychological costs. Job resources are those aspects of a job that help employees cope with high job demands, attain work goals and performance, and stimulate professional growth. Examples of job resources are feedback, task variety, support, and autonomy [15]. In line with Demerouti [16] and Parker and Grote [9], we argue that during and after the implementation of a new technology and workplace automation both job demands and job resources are subject to substantial changes. A recent systematic literature review [17] on the impact of the implementation of technological innovations on core work characteristics, showed that the implementation of a new technology was associated with intensified job demands, including job complexity and workload. Additionally, the relationship between the implementation of a technological innovation and job resources was predominantly positive, especially with regard to autonomy and control. These findings suggest that although job demands tend to increase after the introduction of a new technology, job resources seem, at least to some extent, compensate for these increased demands. However, in finding an answer to the question which work characteristics are susceptible to change after the introduction of an RPA technology, it is important to take a closer look at the defining features of RPA.
Starting with job resources, as mentioned above, one of the main goals of RPA is to take over administrative and repetitive work tasks from employees [5]. This means that the use of RPA frees time that employees otherwise had to spend on monotonous tasks. Considering that RPA generates more time for other aspects of the job, this should allow employees to exert more control over their work structure and tasks. As such, we expect that RPA use relates to more autonomy at work for employees. This notion is also supported by a qualitative interview study of Engberg and Sördal [18], who found that the introduction of RPA enhanced the experienced freedom of employees to independently organize their work schedule and tasks.
Second, although RPA is useful in replacing structured and repetitive tasks, it is less suitable to take over complex work that requires more advanced problem-solving skills and abilities [3]. Taking into account that RPA technology releases employees from carrying out repetitive work duties, it simultaneously leaves more room to perform other and more challenging tasks. In line with this argumentation, several qualitative studies have shown that, overall, employees experienced that RPA enabled them to advance their skill set. In addition the introduction of RPA enabled them to devote time to their professional development and growth while performing new and challenging tasks [18, 19]. These findings suggest that RPA creates space for employees to focus on a variety of challenging work tasks. Therefore, we also expect that the use of RPA positively relates to task variety, which entails the extent to which employees experience variety in their job content and can perform a wide range of tasks that require different skills [20].
Turning to job demands, reference [21] indicates that RPA is able to take over and process up to 300% more information compared to human employees. This increase in productivity is due to the fact that RPA can complete a large range of administrative tasks in a fraction of the time compared to actual employees and can work throughout the night and weekend. Additionally, RPA is relatively easy to implement and configure, meaning that employees can use RPA, as well as make changes in how tasks are performed, without an extensive technical background [22]. This implies that employees are no longer bothered with continuously having to deal with processing and analyzing large amounts of information and are able to easily adjust the system during the implementation process based on the requirements and needs of their job. Information processing refers to the amount of data and information that employees are required to monitor and manage in their job [20, 23]. Considering that RPA takes over data and information processing tasks to a substantial extent, we propose that RPA completes a large range of administrative tasks in a fraction of the time compared to actual employees. Taken together, with regard to changes in job demands and job resources we formulate the following hypotheses: Hypothesis 1:RPA use is positively related to (a) autonomy and (b) task variety. Hypothesis 2:RPA use is negatively related to information processing.
Employee well-being refers to a passive or active work-related affect and individual’s evaluation of the quality of experiences at work [24]. In this study, we included work engagement and exhaustion as indicators of work-related well-being, considering that both are regarded as important factors in the operationalization of employee well-being [25, 26]. In relation to work-related well-being, the JD-R framework proposes two independent underlying processes [15]. First, a health impairment process, in which continued exposure to high job demands results in strain, burnout, and an overall decline in health-related outcomes. Second, a motivational process is proposed, in which access to sufficient job resources protects employees against high job demands and leads to motivation, work engagement, and increased productivity. Following these central assumptions, we argue that higher levels of autonomy and task variety associated with RPA use instigate the motivational process as proposed in the JD-R framework. To clarify, autonomy and task variety are key job resources, which consistently have been found to be predictive of work engagement and performance outcomes (for overviews see [27, 28]. Consequently, we propose that employees who can turn over their repetitive tasks to RPA are likely to experience more autonomy and task variety, and in turn feel more engaged. In addition, consistent exposure to high job demands, including workload and information processing, are linked to increased levels of exhaustion and burnout (e.g. [29]. With regard to information processing, we expect that employees who can transfer their administrative responsibilities to RPA and thus on a daily basis deal with substantially less repetitive job tasks, experience lower levels of information processing (see Hypothesis 2). In turn, lower levels of information processing are likely to relate to lower levels of exhaustion (i.e., a positive relationship). Therefore, we hypothesize the following: Hypothesis 3:(a) Autonomy and (b) task variety are positively related to work engagement. Hypothesis 4:RPA use is indirectly related to more work engagement through (a) autonomy and (b) task variety. Hypothesis 5:Information processing is positively related to exhaustion. Hypothesis 6:RPA use is indirectly related to less exhaustion through information processing.
Data for this study was collected via an online questionnaire. We recruited data from employees within two large departments of a Dutch Ministry (N = 420). The response rate was 37.33%. In 2019 this Ministry introduced and implemented RPA in their organization. Employees working in the two departments typically hold office jobs, such as administrative workers, financial and legal experts, project managers and members, and HR representatives. We invited both employees who could turn over certain aspects of their work to RPA (i.e., RPA users, who make or control work processes and provide input for the RPA robot; N = 140) and employees whose work was not directly impacted by RPA (N = 280). In the questionnaire employees were asked whether their work was somehow impacted by the introduction of RPA and if so, in what way their work has changed and how they interacted with the robot. Based on these answers a distinction could be made between RPA users and non-RPA users. The group of RPA users consisted of employees from whom RPA took over one or several administrative and repetitive work tasks, such as scanning and filing emails and documents, extracting data, and generating (mass) emails. Additionally, this group also consisted of employees that made or controlled RPA work processes and output, as well as provided new input for the RPA robot. All employees received an email from the Ministry with information about the aim of the study, a link to the online questionnaire, and an explanation of the confidentiality was offered to all respondents. This study obtained approval of the Ethics Review Board.
In the total sample, 54.90% was male and the average age was 48.96 years (SD = 10.85). The mean job tenure was 14.61 years (SD = 11.22) and on average respondents worked for 33.48 hours a week (SD = 4.87). Most employees worked in jobs that required a Bachelor’s Degree (48.10%) or an Associate Degree (12.10%). In terms of demographical variables (i.e., gender, age, weekly workhours, and contract type) RPA users did not differ significantly from non-RPA users. Additionally, we tested for differences between RPA users and non-RPA users on the study main variables by conducting independent samples t-tests in SPSS. Table 1 shows the results of these analyses. RPA users reported significantly lower levels of autonomy, task variety, and information processing compared to non-RPA users.
RPA users | Non-RPA users | ||||
---|---|---|---|---|---|
M | SD | M | SD | ||
Autonomy | 3.62 | 0.74 | 3.97 | 0.65 | 4.86** |
Task variety | 3.33 | 0.82 | 3.68 | 0.70 | 4.59** |
Inform. Processing | 3.83 | 0.65 | 4.02 | 0.67 | 2.82** |
Work engagement | 4.71 | 0.99 | 4.69 | 0.90 | −0.22 |
Exhaustion | 2.07 | 0.75 | 2.01 | 0.68 | −1.15 |
Results of
Note:
Frist, autonomy was measured with a Dutch translation of three items of the Work Design Questionnaire (WDQ; [20]). An example item of this scale is: “The job allows me to make a lot of decisions on my own”. Cronbach’s α was 0.80. Task variety was measured with two items of the WDQ [20]. One of these items is “The job involves a great deal of task variety”. Information processing was measured with two items of the WDQ . An example of these items is: “The job requires me to monitor a great deal of information”. Work engagement was measured with the three-item version of the Utrecht Work Engagement Scale [30]. An example item of this scale is: “At my work, I feel bursting with energy”. Cronbach’s α for this scale was 0.82. Exhaustion was measured with three items of the Burnout Assessment Tool (BAT [31]). One of the items is: “I feel mentally exhausted at work”. Cronbach’s α for this scale was 0.81.
First, we evaluated the measurement model using confirmatory factor analysis (CFA). Latent variables (i.e., autonomy, task variety, information processing, work engagement, and exhaustion) were modeled with scale items. The following fit indices were used to evaluate model fit: the Comparative Fit Index (CFI), the Tucker-Lewis Index (TLI), and the root mean square error of approximation (RMSEA). With CFI and TLI values above 0.95, and RMSEA below 0.06, model fit is acceptable [32]. Second, we tested the proposed research model using structural equation (SEM) with the AMOS software package [33]. To assess the specific indirect effects of autonomy and task variety in the relationship between RPA use and work engagement, as well as the specific indirect effect of information processing in the relationship between RPA use and exhaustion, we applied the phantom model approach [34]. In addition, to test the robustness of our proposed research model, we tested an alternative model, that proposed a relationship between RPA use and work engagement, and in turn, autonomy and task variety. Additionally, this alternative model proposed an indirect relationship between RPA use, exhaustion, and information processing.
In Table 2 the descriptive statistics, including the means, standard deviations, and correlations of the variables in this study can be found. Job level was the only demographic variable that correlated significantly with several of the outcome variables (i.e., autonomy, task variety, and information processing). Therefore, we controlled for job level in our further analyses.
Mean | SD | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
---|---|---|---|---|---|---|---|---|---|---|
1. Age | 48.96 | 10.85 | — | |||||||
2. Job level | 2.72 | 0.68 | −0.01 | — | ||||||
3. System use | 0.33 | 0.47 | −0.08 | −0.25** | — | |||||
4. Autonomy | 3.85 | 0.70 | 0.03 | 0.34** | −0.24** | — | ||||
5. Task variety | 3.56 | 0.76 | −0.05 | 0.48** | −0.23** | 0.47** | — | |||
6. Information processing | 3.96 | 0.67 | 0.07 | 0.37** | −0.14** | 0.36** | 0.36** | — | ||
7. Work engagement | 4.70 | 0.92 | 0.05 | 0.05 | 0.01 | 0.28** | 0.32** | −0.14*** | — | |
8. Exhaustion | 2.04 | 0.71 | −0.04 | −0.01 | 0.06 | −0.14** | −0.13** | 0.09 | −0.27** | — |
Descriptive statistics and inter-correlations of the study variables
Note:
The measurement model, including autonomy, task variety, information processing, work engagement, and exhaustion as latent variables, showed a very good fit to the data: χ2 = 144.00, df = 55, CFI = 0.96, TLI = 0.94, RMSEA = 0.06. All factor loadings loaded significantly on their respective latent factor and ranged between 0.63 and 0.97.
In Hypothesis 1a and 1b we predicted that RPA use was positively related to (a) autonomy and (b) task variety. Contrary to our expectations, our analysis showed an opposite relationship, namely that RPA use was significantly and negatively related to both autonomy (β = −0.19, p < 0.01) and task variety (β = −0.13, p < 0.05), thereby not supporting Hypotheses 1a and 1b.
In Hypothesis 2, we predicted that RPA use would be negatively associated with information processing. Although this relationship was indeed negative, it was not significant (β = −0.06, p = 0.17), and thereby not in support of Hypothesis 2.
In line with Hypotheses 3a and 3b, we found that autonomy (β = 0.13, p = 0.01) and task variety (β = 0.26, p < 0.05) were as expected indeed positively and significantly related to work engagement, thereby confirming Hypothesis 3.
Turning to Hypotheses 4a and 4b and the indirect relationship between system use and work engagement through both autonomy and task variety, the data showed that this combined indirect effect was negative and significant (estimate = −0.06, p < 0.02 with a bias-corrected confidence interval ranging from −0.10 to −0.02). To assess the specific indirect effects of autonomy and task variety separately in the relationship between system use and work engagement, the phantom model approach was applied [34]. The specific indirect effect of autonomy in the relation between system use and work engagement was indeed negative and significant (estimate = −0.10, p = 0.02), thereby not in support of Hypothesis 4a. The specific indirect effect of task variety in the relation between system use and work engagement was also negative and significant (estimate = −0.06, p = 0.02). As such, Hypothesis 4b was also not confirmed.
In contrast to Hypothesis 5, we found no significant relationship between information processing and exhaustion, (β = 0.08, p = 0.17). As such, Hypothesis 5 was not supported by the data.
Hypothesis 6, in which an indirect effect of information processing in the relationship between RPA use and exhaustion was hypothesized, was not supported by the data (estimate = −0.01, p = 0.16 with a bias-corrected confidence interval ranging from −0.02 to 0.00). As such, Hypothesis 6 was not confirmed.
Overall, the proposed structural model showed a good fit to the data: χ2 = 210.235, df = 78, CFI = 0.94, TLI = 0.92, RMSEA = 0.06. Figure 1 shows a schematic representation of all study’s results.
Overview of results of structural equation modeling. Note:
Last, we tested a plausible alternative model, in which system use was related to autonomy and task variety, through work engagement. Additionally, in this alternative model we proposed that system use was indirectly related to information processing through exhaustion. The alternative model showed a lower overall fit with the data (χ2 = 248.549 df = 80, CFI = 0.92, TLI = 0.90, RMSEA = 0.07). After comparison of the two models, the proposed research model yielded a significantly better fit (Δχ2 = 38.314, Δdf = 2, p < 0.01).
To gain a better understanding of the impact of workplace automation on the quality of work and employee well-being, we examined to what extent the introduction of RPA relates to work characteristics and subsequent work-related employee well-being. We drew on the JD-R framework [15] to argue for a positive relationship between RPA use (vs. non-use) and the job resources autonomy and task variety, and in turn work engagement. Additionally, we proposed a negative association between RPA use and information processing and subsequently exhaustion. Contrary to our expectations, the results showed that RPA use was negatively related to both autonomy and task variety, which in turn were positively related to work engagement. Moreover, the indirect effects of both autonomy and task variety were negative in the relationship between RPA use and work engagement. These results indicate that the introduction of a workplace automation, and more specifically the use of RPA, is at the expense of work engagement for employees who have to deal with this new technology through a decrease in job resources. Furthermore, we found no significant relationship between RPA use and information processing and in turn exhaustion, suggesting that job demands were not significantly affected by the introduction of a new workplace technology.
Unexpectedly and remarkably, the findings of this study demonstrate that working with RPA as a new technology is associated with lower levels of both autonomy and task variety. This is a worrying finding in itself, especially because autonomy and task variety are important predictors of work engagement, as also underlined by the results of this study. Moreover, many studies have demonstrated that a lack of job resources, including autonomy and task variety, is also associated with other negative work outcomes such as burnout, turnover intentions, lower levels of learning behaviors, as well as a decrease in motivation, proactivity, and performance [35, 36, 37]. This further underlines that it is very important to conserve job resources when introducing a new work process automation.
A possible explanation for the negative association between RPA use and autonomy and task variety - and thus the opposite intended effect of RPA - could lie in the ongoing implementation process of a workplace automation [9]. In this case, RPA was relatively recently introduced within the organization, meaning that the system was still in continuous adjustment to the specific demands of the organization and employees. Although RPA takes over well-structured and repetitive work tasks, the provided output still needs to be regularly checked by human employees. Therefore, it could be that employees working with RPA were still spending considerable time to examine and correct potential system mistakes and updating the robot to certain tasks and needs [38]. Considering that employees needed to search, report, and adjust RPA system errors, this could lead to a decreased sense of autonomy and control. Additionally, because this also requires a different set of work skills, room to engage in new and challenging tasks could be limited. Moreover, employees who had to work with RPA could not freely choose whether RPA took over certain work tasks they previously performed themselves. It could be the case that this lack of individual influence on the use of RPA resulted in a decreased feeling of control. As such, because employees were required to use and learn RPA and did not have a final say in whether RPA was implemented in their work or not, their autonomy may be threatened and thus reduced.
Taken together, the present study findings implicate that after the implementation of a work process automation technology, employee engagement, and thus well-being, is at risk due to a significant decrease in core job resources for RPA users. Additionally, the results of this study showed that RPA use is not related at all to information processing. A possible explanation for this finding may be that information processing simultaneously increases and decreases for RPA users, thereby canceling out any effects. More specifically, it could be that while RPA use relates to less administrative information that has to be analyzed and processed, employees do have to process more information associated with learning to work and getting familiar with RPA, as well as controlling and adjusting RPA processes. In that case, it would be useful to distinguish between different types of information processing related to a digital transition. For instance, information processing associated with the eventual effects of a new technology on individuals work content (and thus an expected decrease in simple and monotonous work tasks), and information processing related to the implementation process and learning a new technology.
Alternatively, other job demands than information processing could be taken into account when examining the impact of RPA on work characteristics. For instance, workload and role conflict could be potential interesting factors in light of the implementation of RPA, considering that the job content is likely to change due to the implementation of a new work process automation technology. Additionally, in the initial phase after a digital transition a new system requires new routines and knowledge, which is likely to have an impact on employees’ workload [39].
Last, we did not found the expected positive relationship between information processing and exhaustion. Exhaustion is often regarded as a more distal outcome compared to work engagement, because employee exhaustion only develops after repeated exposure of (high) job demands [40]. Due to the cross-sectional design of this study that also was conducted only two months after the implementation of RPA, it could be that the health impairment processes, as proposed by the JD-R framework, had not been set in motion yet.
A first important contribution of the current study is that it demonstrates that the relationship between the implementation of technological innovations at work and employee well-being via work characteristics is not straightforward. Our results show that, although RPA is often introduced with the intention to lessen the burden on employees concerning monotonous, repetitive work tasks, this goal is not necessarily achieved. Based on the present study, it seems that job demands do not decrease for those employees that work with the new technology. More importantly and also contrary to our expectations, the use of a new system at work was related to lower instead of higher levels of autonomy and task variety, meaning that job resources of system users seem to decrease after implementation of a work process automation. Thus, our findings demonstrated that the introduction of a new technology did not lower demands. In fact, it even generated less resources in that it created less space for employees to take control over their work and engage in challenging and a wider variety of tasks. Taken together, these findings provide support for the existence of a technology paradox, in that the potential of a new workplace technology does not necessarily results in desired organizational and individual outcomes. Specifically, the implementation of a work process automation should not be at the expense of employee job resources.
Second, the present study contributes to the emerging literature on RPA [5, 6] and offers more insight into workplace automation, and specifically the implementation of RPA, on employee experiences. Whereas earlier studies on the impact of workplace automation and RPA showed overall positive associations with job resources [18, 41, 42], the results of this study present a different picture. Our findings suggest that automation does not always result in a desired reduction of demands, and more importantly, that it poses a potential treat to well-being via a decrease in job resources. To the best of our knowledge this is one of the first papers that focusses on both job resources and a job demand following the implementation of a workplace automation. To gain a deeper understanding of the complex human-technology interaction, future research should place emphasis on changes in both challenging and hindering demands following a digital transition, as well as on job resources that can help employees cope and perform with automation and RPA.
This study has several limitations. First, due to the cross-sectional study design, we cannot draw conclusions about the causal relationships between RPA use, the examined job resources and demand, and work engagement and exhaustion. Although we carefully followed the core premises by the JD-R model [15], it could be the case that some proposed relationships are reciprocal. For instance, it might be that employees who experience high levels of work engagement also perceive more job resources in their work [43]. Earlier studies (e.g. [44, 45] indeed found that job resources and work engagement influence each other in both directions, suggesting a gain cycle in which the presence of job resources and work engagement reinforce each other reciprocally. These findings further underline the importance of more longitudinal research to investigate such bidirectional relationships in a digital transition context. Additionally, when investigating the influence of a technological implementation on employees’ job quality and work experiences, future research could apply a longitudinal study design, in which users and non-users are compared at several measurement points, including pre- and post-implementation. Since employees included in the present study were not randomly assigned to use RPA, the selection of employees to use RPA could be correlated with their perceptions of task variety and job automation. For instance, some employees are more capable and can handle more task variety, so they may be more likely to be selected to use RPA. Thus, it is a challenge to determine the causal effect. Therefore, a within-group pre-post design would have been better and is recommended for future studies.
In addition, the use of self-reports could lead to common method bias [46]. However, additional to the good fit of the measurement model, we conducted Harman’s single-factor test, which demonstrated that variance in the data was not due to a single underlying factor and thus indicating that common method bias was not a problem in this study. Moreover, it can be argued that constructs reflecting individual states, such as work engagement and exhaustion, as well as perceived work characteristics, can best be evaluated by the individual actor, and are not necessarily suitable to cross-validate with other-ratings.
Finally, in this study we focused on (only) three specific work characteristics that were likely to be influenced by the introduction and use of RPA, namely autonomy, task variety, and information processing. The choice of these work characteristics was based on earlier qualitative research findings on the impact of RPA on job resources [18]. Moreover, we reasoned that the implementation of RPA lessens the amount of information that needs to be processed by human employees, as well as generates more control and room for other challenging tasks. Considering that we found no relationship between RPA use and information processing, it would be particularly interesting to uncover if and how other job demands of system users are affected by the implementation of a workplace automation. For instance, future research could further differentiate between challenging and hindering job demands, were job hindrances (e.g., job insecurity, role conflict, and constraints) are associated with exhaustion and job challenges (e.g., workload and cognitive demands) with engagement [47]. It could be that the implementation of new technologies at work simultaneously incite hinderances and challenges for employees. More insight into how workplace automation affects these specific job demands could contribute to a better implementation of new technologies and optimize adaption among employees who have to work with these technologies [9]. Similarly, it would be relevant to examine what and how job resources can help employees to achieve their goals and stay motivated during the introduction of a new technology [16]. In sum, it is of key importance to design jobs in such a way that a digital transition involves both challenging and realizable job demands, as well as sufficient job resources to stimulate employee performance and well-being. A human-centered approach to workplace automation and job design with particular consideration for employee work experiences is of key importance in reducing the technology-paradox and optimizing the full potential of technology [8].
The present study connects to a broader debate on the quality of work in the rapid-changing contemporary world of work [48, 49]. Both employees and managers benefit greatly from a healthy and motivating work environment, especially in times of digital transition and widespread automation within organizations. The findings of this study provide further insight into how technological innovations relate to employee well-being through work characteristics and underline the importance of stimulating autonomy and task variety in order to safeguard employee motivation after introducing a workplace automation.
Facilitating a work environment in which employees have access to sufficient job resources that help them deal and work with technological advancements, as well as enabling good performance, is one of the most important implications for practice. Based on the results of this study and in line with the recommendations of reference [16], organizations and HR practitioners should take responsibility during and after the implementation of new technologies. One of the focal points should be to (re)design jobs in such a way that technological innovations turn into a resource itself by closely paying attention to the needs and concerns of users. Carefully identifying how job demands may change after a digital transition can also help organizations to offer appropriate job resources for employees to cope with changes in their job demands. For instance, access to sufficient training and education can help employees to become acquainted and more proficient in using a new technology, and thereby also reducing workload, anxiety, and job insecurity [50]. Additionally, providing feedback and support from the organization and managers are two main resources for employees that help them deal with the negative consequences of job demands [51]. Furthermore, another way to successfully gain and maintain well-being and motivation during a digital transition, is by facilitating employee job crafting [52] which refers to an individual proactive strategy to seek out relevant job resources that can help employees during technological change. Managers and organizations play a key role in creating a work environment in which employees feel encouraged to engage in job crafting and proactively seek out resources they need to adjust and perform [53].
In sum, during and following the implementation of a technological innovation, organizations and managers should be aware of changes in job demands and needs from employees, as well as focus on providing adequate resources for employees to cope with these demands and to stimulate optimal performance with a new technology.
The current study demonstrates that the introduction of a workplace automation system may have a profound negative impact on employee job resources. More specifically, the findings indicate that use of an automation system relates to lower levels of autonomy and variation in work tasks, forming a serious threat to the work engagement of employees who have to work with the new system. As such, this study shows that organizations should take a close look at and take into account potentially affected job resources due to the implementation of a workplace automation. Importantly, focusing on stimulating relevant job resources, such as autonomy and task variety, during and after digital transitions is necessary to maintain and promote employee well-being and motivation.
This research was funded by a grant from A + O fonds Rijk, an independent Dutch Foundation for innovation and research within the Dutch Government.
Ove Odredbe i uvjeti ističu pravila i regulacije u svezi korištenja IntechOpenove stranice www.intechopen.com i svih poddomena u vlasništvu IntechOpena, tvrtke sa sjedištem u 5 Princes Gate Court, London, SW7 2QJ, Ujedinjeno Kraljevstvo.
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\\n\\nSljedeća terminologija odnosi se na Odredbe i uvjete, te na sve naše ugovore:
\\n\\nKlijent, stranka, vi, vaš odnosi se na vas, osobu koja pristupa ovoj stranici i prihvaća IntechOpenove Odredbe i uvjete;
\\n\\nKompanija, tvrtka, mi, naše odnosi se na tvrtku IntechOpen;
\\n\\nStranke, strane odnosi se na klijenta i na nas, ili samo na klijenta ili nas.
\\n\\nSve odredbe koje se odnose na ponudu, prihvat ili razmatranje plaćanja, a za koja mi pružamo asistenciju klijentu, bilo na ugovoreni ili fiksni način, a s ciljem da se ostvare potrebe i želje klijenta u svezi s našim uslugama, su podložne zakonskim odredbama Ujedinjenog Kraljevstva.
\\n\\nOsim ako nije suprotno navedeno, IntechOpen i/ili svi davatelji licence vlasnici su intelektualnog vlasništva nad svim materijalima na www.intechopen.com. Sva prava intelektualnog vlasništva su pridržana. Stranice sa www.intechopen.com možete gledati, preuzimati, dijeliti, dijeliti poveznice i printati za osobnu uporabu, a temeljem pravila sadržanih u ovim Odredbama i uvjetima.
\\n\\nMi koristimo kolačiće. Korištenjem IntechOpenove stranice slažete se s korištenjem kolačića u skladu s IntechOpenovom Politikom privatnosti. Većina modernih, interaktivnih stranica koristi kolačiće kako bi omogućila ponovno pronalaženje korisničkih detalja kod svakog posjeta. Na našoj stranici kolačići se uglavnom koriste kako bi omogućili funkcionalnost i olakšali posjetiteljima korištenje stranice.
\\n\\nIntechOpen ili njegovi suradnici niti u jednom slučaju neće biti odgovorni za štete (štete uključuju gubitak podataka ili profita, druge poslovne prekide, te sve ostale štete) koje nastanu zbog korištenja materijala na IntechOpenovoj stranici ili nemogućnosti da se iste koriste, čak i ako je IntechOpen ili njegov predstavnik o takvoj šteti obaviješten pismenim ili usmenim putem. Neke jurisdikcije ne dozvoljavaju ograničenja garancija ili ograničenja obveza za posljedične ili slučajne štete pa se u tom slučaju ova ograničenja možda ne odnose na vas.
\\n\\nMaterijali koji se pojavljuju na IntechOpenovoj stranici mogu sadržavati manje greške, tipfelere ili fotografske greške. IntechOpen može napraviti promjene na bilo kojem materijalu koji se nalazi na stranici u bilo koje vrijeme.
\\n\\nIntechOpen nije formalno povezan niti s jednom vanjskom stranicom čije poveznice vode na www.intechopen.com, osim ako to nije izravno navedeno. Iz tog razloga IntechOpen nije odgovoran za sadržaj koji se pojavljuje na takvim stranicama. Poveznica na IntechOpenovu stranicu ne implicira povezanost sa IntechOpenom. Korištenje takvih poveznica isključiva je odgovornost korisnika.
\\n\\nZadržavamo pravo vlasništva nad cjelokupnom stranicom www.intechopen.com i nad svim materijalom na toj stranici. Koristeći se našim uslugama, slažete se da maknete sve poveznice na našu stranicu odmah nakon što to od vas zatražimo. Također, zadržavamo pravo da ove Odredbe i uvjete, i politiku o poveznicama izmjenimo u bilo koje vrijeme. Koristeći se poveznicama na naše stranice slažete se s ovim Odredbama i uvjetima.
\\n\\nAko smatrate da je bilo koja poveznica na našoj stranici sumnjiva iz bilo kojeg razloga, molimo vas da nas kontaktirate. U tom slučaju razmotrit ćemo micanje poveznice s naše stranice, iako nismo obvezni to napraviti.
\\n\\nBez prethodne privole i izričite pisane dozvole, ne možete stvarati okvire oko naših stranica ili koristiti druge tehnike koje na bilo koji način mogu promijeniti prezentaciju ili izgled naše stranice.
\\n\\nIntechOpen može ove Odredbe izmijeniti u bilo koje vrijeme i bez prethodne obavijesti. Koristeći ovu stranicu vi se slažete s trenutnim Odredbama i uvjetima koje su na snazi.
\\n\\nOve Odredbe i uvjeti su sastavljeni u skladu s odredbama prava Ujedinjenog Kraljevstva, a za sve sporove nadležan je sud u Londonu, Ujedinjeno Kraljevstvo.
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\n\nSljedeća terminologija odnosi se na Odredbe i uvjete, te na sve naše ugovore:
\n\nKlijent, stranka, vi, vaš odnosi se na vas, osobu koja pristupa ovoj stranici i prihvaća IntechOpenove Odredbe i uvjete;
\n\nKompanija, tvrtka, mi, naše odnosi se na tvrtku IntechOpen;
\n\nStranke, strane odnosi se na klijenta i na nas, ili samo na klijenta ili nas.
\n\nSve odredbe koje se odnose na ponudu, prihvat ili razmatranje plaćanja, a za koja mi pružamo asistenciju klijentu, bilo na ugovoreni ili fiksni način, a s ciljem da se ostvare potrebe i želje klijenta u svezi s našim uslugama, su podložne zakonskim odredbama Ujedinjenog Kraljevstva.
\n\nOsim ako nije suprotno navedeno, IntechOpen i/ili svi davatelji licence vlasnici su intelektualnog vlasništva nad svim materijalima na www.intechopen.com. Sva prava intelektualnog vlasništva su pridržana. Stranice sa www.intechopen.com možete gledati, preuzimati, dijeliti, dijeliti poveznice i printati za osobnu uporabu, a temeljem pravila sadržanih u ovim Odredbama i uvjetima.
\n\nMi koristimo kolačiće. Korištenjem IntechOpenove stranice slažete se s korištenjem kolačića u skladu s IntechOpenovom Politikom privatnosti. Većina modernih, interaktivnih stranica koristi kolačiće kako bi omogućila ponovno pronalaženje korisničkih detalja kod svakog posjeta. Na našoj stranici kolačići se uglavnom koriste kako bi omogućili funkcionalnost i olakšali posjetiteljima korištenje stranice.
\n\nIntechOpen ili njegovi suradnici niti u jednom slučaju neće biti odgovorni za štete (štete uključuju gubitak podataka ili profita, druge poslovne prekide, te sve ostale štete) koje nastanu zbog korištenja materijala na IntechOpenovoj stranici ili nemogućnosti da se iste koriste, čak i ako je IntechOpen ili njegov predstavnik o takvoj šteti obaviješten pismenim ili usmenim putem. Neke jurisdikcije ne dozvoljavaju ograničenja garancija ili ograničenja obveza za posljedične ili slučajne štete pa se u tom slučaju ova ograničenja možda ne odnose na vas.
\n\nMaterijali koji se pojavljuju na IntechOpenovoj stranici mogu sadržavati manje greške, tipfelere ili fotografske greške. IntechOpen može napraviti promjene na bilo kojem materijalu koji se nalazi na stranici u bilo koje vrijeme.
\n\nIntechOpen nije formalno povezan niti s jednom vanjskom stranicom čije poveznice vode na www.intechopen.com, osim ako to nije izravno navedeno. Iz tog razloga IntechOpen nije odgovoran za sadržaj koji se pojavljuje na takvim stranicama. Poveznica na IntechOpenovu stranicu ne implicira povezanost sa IntechOpenom. Korištenje takvih poveznica isključiva je odgovornost korisnika.
\n\nZadržavamo pravo vlasništva nad cjelokupnom stranicom www.intechopen.com i nad svim materijalom na toj stranici. Koristeći se našim uslugama, slažete se da maknete sve poveznice na našu stranicu odmah nakon što to od vas zatražimo. Također, zadržavamo pravo da ove Odredbe i uvjete, i politiku o poveznicama izmjenimo u bilo koje vrijeme. Koristeći se poveznicama na naše stranice slažete se s ovim Odredbama i uvjetima.
\n\nAko smatrate da je bilo koja poveznica na našoj stranici sumnjiva iz bilo kojeg razloga, molimo vas da nas kontaktirate. U tom slučaju razmotrit ćemo micanje poveznice s naše stranice, iako nismo obvezni to napraviti.
\n\nBez prethodne privole i izričite pisane dozvole, ne možete stvarati okvire oko naših stranica ili koristiti druge tehnike koje na bilo koji način mogu promijeniti prezentaciju ili izgled naše stranice.
\n\nIntechOpen može ove Odredbe izmijeniti u bilo koje vrijeme i bez prethodne obavijesti. Koristeći ovu stranicu vi se slažete s trenutnim Odredbama i uvjetima koje su na snazi.
\n\nOve Odredbe i uvjeti su sastavljeni u skladu s odredbama prava Ujedinjenog Kraljevstva, a za sve sporove nadležan je sud u Londonu, Ujedinjeno Kraljevstvo.
\n"}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. 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Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"993",title:"Pre-Hospital Emergency Medicine",slug:"critical-care-medicine-pre-hospital-emergency-medicine",parent:{id:"173",title:"Critical Care Medicine",slug:"critical-care-medicine"},numberOfBooks:3,numberOfSeries:0,numberOfAuthorsAndEditors:69,numberOfWosCitations:18,numberOfCrossrefCitations:13,numberOfDimensionsCitations:22,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"993",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"5970",title:"Bedside Procedures",subtitle:null,isOpenForSubmission:!1,hash:"ba56d3036ac823a7155f40e4a02c030d",slug:"bedside-procedures",bookSignature:"Gabriel Cismaru",coverURL:"https://cdn.intechopen.com/books/images_new/5970.jpg",editedByType:"Edited by",editors:[{id:"191888",title:"Dr.",name:"Gabriel",middleName:null,surname:"Cismaru",slug:"gabriel-cismaru",fullName:"Gabriel Cismaru"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5756",title:"Intensive Care",subtitle:null,isOpenForSubmission:!1,hash:"c15f872f6c0158a19bf64f081fe1e854",slug:"intensive-care",bookSignature:"Nissar Shaikh",coverURL:"https://cdn.intechopen.com/books/images_new/5756.jpg",editedByType:"Edited by",editors:[{id:"107703",title:"Dr.",name:"Nissar",middleName:null,surname:"Shaikh",slug:"nissar-shaikh",fullName:"Nissar Shaikh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5220",title:"Oncology Critical Care",subtitle:null,isOpenForSubmission:!1,hash:"6ca48669ac7afaf59398a958335eff65",slug:"oncology-critical-care",bookSignature:"Jeffrey B. Hoag",coverURL:"https://cdn.intechopen.com/books/images_new/5220.jpg",editedByType:"Edited by",editors:[{id:"91738",title:"Dr.",name:"Jeffrey",middleName:null,surname:"Hoag",slug:"jeffrey-hoag",fullName:"Jeffrey Hoag"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:3,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"52089",doi:"10.5772/64372",title:"Infections in Cancer Patients",slug:"infections-in-cancer-patients",totalDownloads:2569,totalCrossrefCites:4,totalDimensionsCites:5,abstract:"Cancer therapy is a dynamically evolving field. Chemotherapy and biologic agents impact the magnitude and duration of immunosuppression in the already-immunocompromised cancer hosts who are then susceptible to a broad spectrum of infectious complications ranging from mild opportunistic infections to severe, fatal neutropenic sepsis. Numerous bacterial, fungal, and viral organisms have been implicated dictating varied preventative approaches. Rapid assessment and risk stratification of febrile patients identify individuals requiring hospital admission. Timely delivery of antimicrobials reduces the risk of complications and death. Herein, we summarize the current “state of art” in the management of infection in the cancer patient. We detail the advances in antibacterial and antifungal therapy.",book:{id:"5220",slug:"oncology-critical-care",title:"Oncology Critical Care",fullTitle:"Oncology Critical Care"},signatures:"Deepjot Singh and Robert A. Bonomo",authors:[{id:"181936",title:"Dr.",name:"Deepjot",middleName:null,surname:"Singh",slug:"deepjot-singh",fullName:"Deepjot Singh"},{id:"187145",title:"Dr.",name:"Robert",middleName:null,surname:"Bonomo",slug:"robert-bonomo",fullName:"Robert Bonomo"}]},{id:"55443",doi:"10.5772/intechopen.68630",title:"Aneurysmal Subarachnoid Hemorrhage",slug:"aneurysmal-subarachnoid-hemorrhage",totalDownloads:2940,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"Aneurysmal subarachnoid hemorrhage (SAH) is a devastating neurological syndrome, which occurs at a rate of 3–25 per 100,000 population. Smoking and hypertension are the most important risk factors of subarachnoid hemorrhage. Rupture of cerebral aneurysm leads to rapid spread of blood into cerebrospinal fluid and subsequently leads to sudden increase of intracranial pressure and severe headache. Subarachnoid hemorrhage is associated with neurological (such as re‐bleeding and vasospasm) and systemic (such as myocardial injury and hyponatremia) complications that are causes of high mortality and morbidity. Although patients with poor‐grade subarachnoid hemorrhage are at higher risk of neurological and systemic complications, the early and aggressive management of this group of patient has decreased overall mortality by 17% in last 40 years. Early aneurysm repair, close monitoring in dedicated neurological intensive care unit, prevention, and aggressive management of medical and neurological complications are the most important strategies to improve outcome.",book:{id:"5756",slug:"intensive-care",title:"Intensive Care",fullTitle:"Intensive Care"},signatures:"Adel E. Ahmed Ganaw, Abdulgafoor M. Tharayil, Ali O. Mohamed\nBel Khair, Saher Tahseen, Jazib Hassan, Mohammad Faisal Abdullah\nMalmstrom and Sohel Mohamed Gamal Ahmed",authors:[{id:"198979",title:"Dr.",name:"Saher",middleName:null,surname:"Tahseen",slug:"saher-tahseen",fullName:"Saher Tahseen"},{id:"199923",title:"Dr.",name:"Adel. E. Ahmad",middleName:null,surname:"Ganaw",slug:"adel.-e.-ahmad-ganaw",fullName:"Adel. E. Ahmad Ganaw"},{id:"200584",title:"Dr.",name:"Abdulgafoor",middleName:null,surname:"Tharayil",slug:"abdulgafoor-tharayil",fullName:"Abdulgafoor Tharayil"},{id:"205193",title:"Dr.",name:"Ali",middleName:"O Mohamed",surname:"Bel Khair",slug:"ali-bel-khair",fullName:"Ali Bel Khair"},{id:"205194",title:"Dr.",name:"Jazib",middleName:null,surname:"Hassan",slug:"jazib-hassan",fullName:"Jazib Hassan"},{id:"205195",title:"Dr.",name:"M. Faisal",middleName:null,surname:"Malmstrom",slug:"m.-faisal-malmstrom",fullName:"M. Faisal Malmstrom"},{id:"205787",title:"Dr.",name:"Sohel Mohamed Gamal",middleName:null,surname:"Ahmed",slug:"sohel-mohamed-gamal-ahmed",fullName:"Sohel Mohamed Gamal Ahmed"}]},{id:"56878",doi:"10.5772/intechopen.70498",title:"Lumbar Puncture of the Newborn",slug:"lumbar-puncture-of-the-newborn",totalDownloads:1462,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"Heinrich Irenäus Quincke was the first person in medical history to perform lumbar puncture (LP). Indications of lumbar puncture include suspected meningitis, suspected subarachnoid hemorrhage, administration of chemotherapeutic agents, instillation of contrast media for imaging of the spinal cord, and the evaluation of various neurologic conditions including normal pressure hydrocephalus and Guillain-Barré syndrome, and the treatment of idiopathic intracranial hypertension. Contraindications of lumbar puncture include findings of increased intracranial pressure, bleeding diathesis, cardiopulmonary instability, soft tissue infection at the puncture site, shock, respiratory insufficiency, and suspected meningococcal septicemia with extensive or spreading purpura. Altered mental status, focal neurologic signs, papilledema, focal seizure, and risk for brain abscess are indications for cranial imaging before performing LP. Lack of local anesthetic use and advancement of the spinal needle with the stylet in place were most prominent risk factors for a traumatic LP. Ultrasound may minimize the number of LP attempts and decrease patient and parent anxiety by easily identifying an insertion site. Infection, spinal hematoma, epidermoid tumor, and cerebral herniation are the main complications of LP. When LP is traumatic, the wisest approach is to assume the patient is having meningitis and start empirical therapy.",book:{id:"5970",slug:"bedside-procedures",title:"Bedside Procedures",fullTitle:"Bedside Procedures"},signatures:"Selim Öncel",authors:[{id:"200133",title:"Associate Prof.",name:"Selim",middleName:null,surname:"Öncel",slug:"selim-oncel",fullName:"Selim Öncel"}]},{id:"54793",doi:"10.5772/intechopen.68308",title:"Intensive Care Unit Workforce: Occupational Health and Safety",slug:"intensive-care-unit-workforce-occupational-health-and-safety",totalDownloads:2221,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"There are many different work tasks and workplace hazards related to the ICU setting. The workplace hazards include the physical environment of the ICU, working conditions, psychosocial factors, ergonomic factors, biological factors and chemical factors that cause ICU workers to have health problems. The occurrence of occupational health problems in ICU workers not only leads to decreased job satisfaction and productivity but also increases absenteeism and burnout. Moreover, this situation adversely affects patient care and increases the cost of treatment. Recognising occupational hazards and risks arising from the work environment will assist in planning strategies to protect and promote health programmes for ICU workers. Understanding the importance of occupational health and safety practices by all institutions is a key factor to improve quality of life, work efficiency and work satisfaction of ICU workers.",book:{id:"5756",slug:"intensive-care",title:"Intensive Care",fullTitle:"Intensive Care"},signatures:"Melek Nihal Esin and Duygu Sezgin",authors:[{id:"183522",title:"Prof.",name:"Melek Nihal",middleName:null,surname:"Esin",slug:"melek-nihal-esin",fullName:"Melek Nihal Esin"},{id:"197030",title:"Dr.",name:"Duygu",middleName:null,surname:"Sezgin",slug:"duygu-sezgin",fullName:"Duygu Sezgin"}]},{id:"54955",doi:"10.5772/intechopen.68348",title:"Acute Kidney Injury in the Intensive Care Unit",slug:"acute-kidney-injury-in-the-intensive-care-unit",totalDownloads:2452,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"Acute kidney injury (AKI) is defined as an abrupt decrease in glomerular filtration rate (GFR). Incidence varies from 20% to as high as 70% in critically ill patients. Classically, AKI has been divided into three broad pathophysiologic categories: prerenal AKI, intrinsic AKI, and postrenal (obstructive) AKI. The clinical manifestations of AKI vary among a wide range of symptoms and metabolic abnormalities. A sudden decrease in GFR will result in rising concentrations of solutes in the blood, which are normally excreted by the kidneys. Recently, new urinary and serum biomarkers have gained a place in the diagnosis, classification, and prognosis prediction of AKI. The best treatment for AKI is prevention. Patients with prerenal azotemia should have intravascular volume deficits corrected and cardiac function optimized. Obstructive (postrenal) kidney disease is treated by mechanical relief of the block. The primary management of acute interstitial nephritis is discontinuation of the inciting agent. Renal replacement therapy (RRT) has emerged as a supportive mechanism rather than just as a lifesaving measure. Continuous techniques are preferable in treating critically ill patients, although every modality has its benefits, indications, and contraindications.",book:{id:"5756",slug:"intensive-care",title:"Intensive Care",fullTitle:"Intensive Care"},signatures:"Jose J. Zaragoza and Faustino J. Renteria",authors:[{id:"181646",title:"Dr.",name:"Jose",middleName:"Jesus",surname:"Zaragoza",slug:"jose-zaragoza",fullName:"Jose Zaragoza"},{id:"200843",title:"Dr.",name:"Faustino",middleName:null,surname:"Renteria",slug:"faustino-renteria",fullName:"Faustino Renteria"}]}],mostDownloadedChaptersLast30Days:[{id:"55736",title:"Haemodynamic Monitoring in the Intensive Care Unit",slug:"haemodynamic-monitoring-in-the-intensive-care-unit",totalDownloads:3370,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Monitoring is a cognitive aid that allows clinicians to detect the nature and extent of pathology and helps assessment of response to therapy. The cardiovascular system is the most commonly monitored organ system in the critical care setting. It helps identify the presence and nature of shock and guides response to resuscitation by detection of cardiac rate and rhythm, evaluation of volume state, cardiac contractility and systemic vascular resistance. Newer technologies allow greater assessment of oxygen delivery to vulnerable tissues. We discuss the nature, history, modalities and interpretation of the most commonly available haemodynamic monitoring methods in clinical use currently.",book:{id:"5756",slug:"intensive-care",title:"Intensive Care",fullTitle:"Intensive Care"},signatures:"Mainak Majumdar",authors:[{id:"86678",title:"Dr.",name:"Mainak",middleName:null,surname:"Majumdar",slug:"mainak-majumdar",fullName:"Mainak Majumdar"}]},{id:"56744",title:"Endotracheal Intubation in Children: Practice Recommendations, Insights, and Future Directions",slug:"endotracheal-intubation-in-children-practice-recommendations-insights-and-future-directions",totalDownloads:2450,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"Management of airway is mandatory in a critically ill child with severe trauma or any other situation that threatens his or her life. It is important, that clinicians who attend critically ill pediatric patients requiring airway management know the rapid sequence intubation (RSI) procedure, identify a patient with difficult airway, know the devices and techniques for the management of difficult airway, and look for receiving a formal training in endotracheal intubation (ETI). Future strategies for teaching and/or training clinicians in pediatric and neonatal ETI should be evaluated through conducting controlled clinical trials to identify which type will be the most effective by considering the less number of attempts and complications.",book:{id:"5970",slug:"bedside-procedures",title:"Bedside Procedures",fullTitle:"Bedside Procedures"},signatures:"Maribel Ibarra-Sarlat, Eduardo Terrones-Vargas, Lizett Romero-\nEspinoza, Graciela Castañeda-Muciño, Alejandro Herrera-Landero\nand Juan Carlos Núñez-Enríquez",authors:[{id:"166303",title:"Dr.",name:"Juan",middleName:"Carlos",surname:"Nuñez-Enriquez",slug:"juan-nunez-enriquez",fullName:"Juan Nuñez-Enriquez"},{id:"206296",title:"Dr.",name:"Eduardo",middleName:null,surname:"Terrones-Vargas",slug:"eduardo-terrones-vargas",fullName:"Eduardo Terrones-Vargas"},{id:"206297",title:"Dr.",name:"Maribel",middleName:null,surname:"Ibarra-Sarlat",slug:"maribel-ibarra-sarlat",fullName:"Maribel Ibarra-Sarlat"},{id:"206298",title:"Dr.",name:"Lizett",middleName:null,surname:"Romero-Espinoza",slug:"lizett-romero-espinoza",fullName:"Lizett Romero-Espinoza"},{id:"206299",title:"Dr.",name:"Alejandro",middleName:null,surname:"Herrera-Landero",slug:"alejandro-herrera-landero",fullName:"Alejandro Herrera-Landero"},{id:"213723",title:"Dr.",name:"Graciela",middleName:null,surname:"Castañeda-Muciño",slug:"graciela-castaneda-mucino",fullName:"Graciela Castañeda-Muciño"}]},{id:"55848",title:"Airway Management in ICU Settings",slug:"airway-management-in-icu-settings",totalDownloads:2864,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Maintenance of patent airway, adequate ventilation, and pulmonary gas exchange is very important in critically ill patients. Airway management in intensive care patients differs significantly from routine surgical procedures in the operating room. The airway competence in intensive care unit (ICU) should be coping with the rapidly evolving advances in airway management. Therefore, efforts should be focused on the three pillars of airway master: airway providers as intensivists or critical care physicians, equipment, and operational plans. Not all institutions can afford all airway equipment in the market; however, they should make sure that critical care providers have a full access to the available tools and they are comfortable using it. Educational sessions and refresher courses should be tailored to meet the competence level of the ICU providers and equipment availability. Operational plan includes developing institutional airway protocols and implementing difficult airway guidelines. The protocols should consider different staffing models of ICU and make sure all the time at least one member of the team with the highest experience in airway should be always available. The aim of writing this chapter is to enable the intensivist to optimize their use of airway equipment and managing high‐risk patients in ICU.",book:{id:"5756",slug:"intensive-care",title:"Intensive Care",fullTitle:"Intensive Care"},signatures:"Nabil Abdelhamid Shallik, Mamdouh Almustafa, Ahmed Zaghw\nand Abbas Moustafa",authors:[{id:"202782",title:"Dr.",name:"Nabil A.",middleName:null,surname:"Shallik",slug:"nabil-a.-shallik",fullName:"Nabil A. Shallik"},{id:"206965",title:"Dr.",name:"Mamdouh",middleName:null,surname:"Almustafa",slug:"mamdouh-almustafa",fullName:"Mamdouh Almustafa"},{id:"206966",title:"Dr.",name:"Ahmed",middleName:null,surname:"Zaghw",slug:"ahmed-zaghw",fullName:"Ahmed Zaghw"},{id:"206967",title:"Dr.",name:"Abbas",middleName:null,surname:"Moustafa",slug:"abbas-moustafa",fullName:"Abbas Moustafa"}]},{id:"56878",title:"Lumbar Puncture of the Newborn",slug:"lumbar-puncture-of-the-newborn",totalDownloads:1461,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"Heinrich Irenäus Quincke was the first person in medical history to perform lumbar puncture (LP). Indications of lumbar puncture include suspected meningitis, suspected subarachnoid hemorrhage, administration of chemotherapeutic agents, instillation of contrast media for imaging of the spinal cord, and the evaluation of various neurologic conditions including normal pressure hydrocephalus and Guillain-Barré syndrome, and the treatment of idiopathic intracranial hypertension. Contraindications of lumbar puncture include findings of increased intracranial pressure, bleeding diathesis, cardiopulmonary instability, soft tissue infection at the puncture site, shock, respiratory insufficiency, and suspected meningococcal septicemia with extensive or spreading purpura. Altered mental status, focal neurologic signs, papilledema, focal seizure, and risk for brain abscess are indications for cranial imaging before performing LP. Lack of local anesthetic use and advancement of the spinal needle with the stylet in place were most prominent risk factors for a traumatic LP. Ultrasound may minimize the number of LP attempts and decrease patient and parent anxiety by easily identifying an insertion site. Infection, spinal hematoma, epidermoid tumor, and cerebral herniation are the main complications of LP. When LP is traumatic, the wisest approach is to assume the patient is having meningitis and start empirical therapy.",book:{id:"5970",slug:"bedside-procedures",title:"Bedside Procedures",fullTitle:"Bedside Procedures"},signatures:"Selim Öncel",authors:[{id:"200133",title:"Associate Prof.",name:"Selim",middleName:null,surname:"Öncel",slug:"selim-oncel",fullName:"Selim Öncel"}]},{id:"55443",title:"Aneurysmal Subarachnoid Hemorrhage",slug:"aneurysmal-subarachnoid-hemorrhage",totalDownloads:2938,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"Aneurysmal subarachnoid hemorrhage (SAH) is a devastating neurological syndrome, which occurs at a rate of 3–25 per 100,000 population. Smoking and hypertension are the most important risk factors of subarachnoid hemorrhage. Rupture of cerebral aneurysm leads to rapid spread of blood into cerebrospinal fluid and subsequently leads to sudden increase of intracranial pressure and severe headache. Subarachnoid hemorrhage is associated with neurological (such as re‐bleeding and vasospasm) and systemic (such as myocardial injury and hyponatremia) complications that are causes of high mortality and morbidity. Although patients with poor‐grade subarachnoid hemorrhage are at higher risk of neurological and systemic complications, the early and aggressive management of this group of patient has decreased overall mortality by 17% in last 40 years. Early aneurysm repair, close monitoring in dedicated neurological intensive care unit, prevention, and aggressive management of medical and neurological complications are the most important strategies to improve outcome.",book:{id:"5756",slug:"intensive-care",title:"Intensive Care",fullTitle:"Intensive Care"},signatures:"Adel E. Ahmed Ganaw, Abdulgafoor M. Tharayil, Ali O. Mohamed\nBel Khair, Saher Tahseen, Jazib Hassan, Mohammad Faisal Abdullah\nMalmstrom and Sohel Mohamed Gamal Ahmed",authors:[{id:"198979",title:"Dr.",name:"Saher",middleName:null,surname:"Tahseen",slug:"saher-tahseen",fullName:"Saher Tahseen"},{id:"199923",title:"Dr.",name:"Adel. E. Ahmad",middleName:null,surname:"Ganaw",slug:"adel.-e.-ahmad-ganaw",fullName:"Adel. E. Ahmad Ganaw"},{id:"200584",title:"Dr.",name:"Abdulgafoor",middleName:null,surname:"Tharayil",slug:"abdulgafoor-tharayil",fullName:"Abdulgafoor Tharayil"},{id:"205193",title:"Dr.",name:"Ali",middleName:"O Mohamed",surname:"Bel Khair",slug:"ali-bel-khair",fullName:"Ali Bel Khair"},{id:"205194",title:"Dr.",name:"Jazib",middleName:null,surname:"Hassan",slug:"jazib-hassan",fullName:"Jazib Hassan"},{id:"205195",title:"Dr.",name:"M. Faisal",middleName:null,surname:"Malmstrom",slug:"m.-faisal-malmstrom",fullName:"M. Faisal Malmstrom"},{id:"205787",title:"Dr.",name:"Sohel Mohamed Gamal",middleName:null,surname:"Ahmed",slug:"sohel-mohamed-gamal-ahmed",fullName:"Sohel Mohamed Gamal Ahmed"}]}],onlineFirstChaptersFilter:{topicId:"993",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:11,numberOfPublishedChapters:91,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:332,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:11,numberOfPublishedChapters:143,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:124,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:112,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:23,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:12,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"7",title:"Biomedical Engineering",doi:"10.5772/intechopen.71985",issn:"2631-5343",scope:"Biomedical Engineering is one of the fastest-growing interdisciplinary branches of science and industry. The combination of electronics and computer science with biology and medicine has improved patient diagnosis, reduced rehabilitation time, and helped to facilitate a better quality of life. Nowadays, all medical imaging devices, medical instruments, or new laboratory techniques result from the cooperation of specialists in various fields. The series of Biomedical Engineering books covers such areas of knowledge as chemistry, physics, electronics, medicine, and biology. 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Currently, he is a professor of Orthodontics. He holds a Certificate of Advanced Study type A in Technology of Biomaterials used in Dentistry (1995); Certificate of Advanced Study type B in Dento-Facial Orthopaedics (1997) from the Faculty of Dental Surgery, University Denis Diderot-Paris VII, France; Diploma of Advanced Study (DESA) in Biocompatibility of Biomaterials from the Faculty of Medicine and Pharmacy of Casablanca (2002); Certificate of Clinical Occlusodontics from the Faculty of Dentistry of Casablanca (2004); University Diploma of Biostatistics and Perceptual Health Measurement from the Faculty of Medicine and Pharmacy of Casablanca (2011); and a University Diploma of Pedagogy of Odontological Sciences from the Faculty of Dentistry of Casablanca (2013). 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:{name:"Medical University Plovdiv",country:{name:"Bulgaria"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. 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Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:null,institution:null},{id:"7227",title:"Dr.",name:"Hiroaki",middleName:null,surname:"Matsui",slug:"hiroaki-matsui",fullName:"Hiroaki Matsui",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Tokyo",country:{name:"Japan"}}},{id:"312999",title:"Dr.",name:"Bernard O.",middleName:null,surname:"Asimeng",slug:"bernard-o.-asimeng",fullName:"Bernard O. 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Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',annualVolume:11404,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"49517",title:"Prof.",name:"Hitoshi",middleName:null,surname:"Tsunashima",fullName:"Hitoshi Tsunashima",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTP4QAO/Profile_Picture_1625819726528",institutionString:null,institution:{name:"Nihon University",institutionURL:null,country:{name:"Japan"}}},{id:"425354",title:"Dr.",name:"Marcus",middleName:"Fraga",surname:"Vieira",fullName:"Marcus Vieira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003BJSgIQAX/Profile_Picture_1627904687309",institutionString:null,institution:{name:"Universidade Federal de Goiás",institutionURL:null,country:{name:"Brazil"}}},{id:"196746",title:"Dr.",name:"Ramana",middleName:null,surname:"Vinjamuri",fullName:"Ramana Vinjamuri",profilePictureURL:"https://mts.intechopen.com/storage/users/196746/images/system/196746.jpeg",institutionString:"University of Maryland, Baltimore County",institution:{name:"University of Maryland, Baltimore County",institutionURL:null,country:{name:"United States of America"}}}]},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering",scope:"The Biotechnology - Biosensors, Biomaterials and Tissue Engineering topic within the Biomedical Engineering Series aims to rapidly publish contributions on all aspects of biotechnology, biosensors, biomaterial and tissue engineering. We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. 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