The technique was emanated in early 1960s; nowadays, deep brain stimulation (DBS) has become a huge practice in treatment of various movement disorders along with some psychiatric disorders. The advancement of DBS in different neurodegenerative diseases and managing patients with refractory brain disorders are closely related to the developments in technology. This development in regard with the device advancement along with the safe coupling of DBS to high-resolution imaging can help us to shape our knowledge in brain-wide networks and circuits linked with clinical aspects. DBS is found to be useful in learning and memory. On the contrary, traditional epilepsy surgeries are more complicated and technologically DBS is easier and more feasible. There are mild adverse effects of this DBS treatment, but a number of studies have shown positive treatment outcome with movement disorders and many kinds of psychiatric disorders too.