Fitri Octaviana
I\'m neurologist, my field is in peripheral nerve, epilepsy and clinical neurophysiology. My research now focuses on HIV neuropathy.
I\'m neurologist, my field is in peripheral nerve, epilepsy and clinical neurophysiology. My research now focuses on HIV neuropathy.
As advances in the treatment of HIV are now allowing patients a longer life span, further comorbidities become apparent. This includes sensory neuropathy (HIV-SN) which can affect a patient’s quality of life. Here, we review factors influencing HIV-SN in patients receiving antiretroviral therapy that promotes this condition and in the modern era when these therapies have been withdrawn. This has halved the incidence of HIV-SN, but the condition remains significant in the lives of many sufferers. Genetic polymorphisms that influence pathogenesis of HIV-SN have indicated likely mechanisms, but studies of skin biopsies and animal models are needed to confirm the roles of the encoded proteins.
Part of the book: Demystifying Polyneuropathy