Huan Ren

Southern University of Science and Technology, Shenzhen

Huan Ren, born in 1967, currently works as a professor in Immunology. She obtained her PhD at University of Liverpool, School of Medicine, Dept of Neuroscience, England. She obtained her master degree in Dept of Immunology, Harbin Medical University in 1997. She established her research group in 2007 at Harbin Medical University, China. Her research mainly focuses on understanding the key events and mechanisms of cancer development and progression, especially the dynamic interaction between tumor cells and their microenvironment, recognizing tumor biomarkers for early diagnosis and relapse, and defining novel therapeutic strategies for patients with malignant tumors. She is a PI for a few funding of National Science Foundation of China. Dr. Ren\'s researches have been published in many scientific journals.

1books edited

2chapters authored

Latest work with IntechOpen by Huan Ren

Protein tyrosine kinase (PTK) deregulation contributes to growth of cancer and many other diseases. The development of small-molecule tyrosine kinase inhibitors (TKIs) that target the deregulated PTKs, such as epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) and Bcr-ABL in chronic myeloid leukemia (CML), has revolutionized disease management. In this book, we examine a few aspects of PTKs and cancer, considering efficacy, predictive markers to therapeutic response, limitations, and future directions in TKI treatment. In this rapidly evolving field, overcoming therapeutic resistance is most challenging, and multi-targeting directs the next-generation TKIs and combination therapy as ongoing strategies in cancer treatment.

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