Socioeconomic and Covid–19 related variables and the data sources.
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Barely three months into the new year and we are happy to announce a monumental milestone reached - 150 million downloads.
\n\nThis achievement solidifies IntechOpen’s place as a pioneer in Open Access publishing and the home to some of the most relevant scientific research available through Open Access.
\n\nWe are so proud to have worked with so many bright minds throughout the years who have helped us spread knowledge through the power of Open Access and we look forward to continuing to support some of the greatest thinkers of our day.
\n\nThank you for making IntechOpen your place of learning, sharing, and discovery, and here’s to 150 million more!
\n\n\n\n\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"1274",leadTitle:null,fullTitle:"Pathogenesis of Encephalitis",title:"Pathogenesis of Encephalitis",subtitle:null,reviewType:"peer-reviewed",abstract:"Many infectious agents, such as viruses, bacteria, and parasites, can cause inflammation of the central nervous system (CNS). 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\r\n\tThere are new approaches and perspectives in treating HIV; however the full impact of these advances has not been released due to nonadherence. Several studies have investigated the reasons for nonadherence among different groups of patients, with alcohol use, treatment fatigue, forgetfulness, relocation among others commonly reported reasons for nonadherence. It is possible that reasons for nonadherence among adolescents differ from older patients and in different settings. Thus, understanding reasons for nonadherence to treatment, especially among adolescents, as well as what works in improving adherence is critical towards maximising the effects of available medications, which are effective in managing HIV and TB. It will be also important to reflect on the advances made so far on how to tackle the issues on drug resistant HIV and progress on vaccine trials for HIV. This book aims to address these critical issues and focuses on up-to-date review of copious literature.
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The communication challenges facing those who wish to design warning messages involve both content and access. Content focuses on gaining attention and providing appropriate instructions for self-protection. Access depends on sending the messages through a channel or channels and a medium or media that can be retrieved quickly and easily. A team of researchers completed a project designed to develop such content and access. The project was based on previous warning message testing research. Specifically, researchers attempted to apply the IDEA model to create brief, easily accessible earthquake early warning messages via a mobile phone app.
\nThe IDEA model for effective instructional risk and crisis communication is an acronym that stands for internalization, distribution, explanation, and action [1]. According to the IDEA model, such messages ought to include appeals to internalization (e.g., proximity, personal relevance, impact, timeliness), be distributed over multiple channels deemed appropriate based on crisis type and target audience(s), and offer cogent explanations about what is happening. These explanations should be offered by credible sources and the scientific information provided in them be both accurate and translated intelligibly for the target population(s). These messages also must include specific action steps receivers are to take (or not take) for self-protection [2, 3, 4, 5, 6, 7]. The following paragraphs describe the message design and testing project processes, results, and conclusions based on the timeline under which it unfolded.
\nThe design and testing process occurred in two phases. Thus, this section first describes the study design process followed by the results of the two-phase experiment. It closes with a discussion of the results as they may inform the design of effective EEW messages delivered via phone apps.
\nTo launch the project, a multidisciplinary group comprised of seismologists, instructional risk and crisis communication scientists, graphic artists, and emergency managers from the US west coast states met in Pasadena, California to participate in a 3-day design storm focused on earthquake early warning messaging. This design storm was essentially a synergistic brainstorming session to formulate an ecologically valid plan based on a broad cross-section of expertise represented in crisis communication and earthquake science that would inform earthquake early warning message design.
\nUltimately, the group agreed that message content
Message content would address
Message content would address
Message content would address
The graphic artists created eight visual representations of a smart phone app screen, which the instructional risk and crisis team would test during the fall semester. The team would create an online survey to collect responses to the various versions and measure their effectiveness based on affective, cognitive, and behavioral learning outcomes. A snowball sample of participants would be invited via Lucy Jones’ Facebook page and the Shakeout website. The survey collected quantitative and qualitative data and employed a mixed methods analysis.
\nThe results for phase one of the project were collected using a survey distributed via an invitation on Lucy Jones’ Facebook page and the Shakeout website. Both outlets targeted users across the US west coast. Of the 469 surveys entered, 198 were completed in entirety and, thus, usable for the analysis. The usable data resulted in 22–28 responses per condition for the eight varieties tested. The sample was comprised of 106 (56%) females and 92 (44%) males. A majority of the participants (80%) were Caucasians from Southern California (n = 153). Notably, 37% (n = 66) of the participants reported earning incomes over $100,000 annually.
\nEight message conditions were manipulated in ways that indicated the location with or without a map, intensity in numerical or non-numerical form, and countdown in graphic or numerical form. All eight conditions used the same aural warning alert sound and voice command. All eight conditions offered actionable vocal instructions to “drop, take cover, and hold on.”
\nSurvey responses were examined using both quantitative and qualitative methods. Statistically significant quantitative results and dominant qualitative themes emerging in open-ended responses are reported here. The quantitative analysis produced five sets of meaningful results. The subsequent qualitative examination of open-ended responses provided additional insight to inform message refinement. In total, 87 participants (44%) offered open-ended responses to the prompt, “Please provide any additional feedback you believe would be helpful concerning the quality of the app.” These comments ranged from 3 to 328 words (M = 50) Exemplars from these responses are reported with the corresponding quantitative results. These sets of results focus on intensity, location, countdown, perceived helpfulness of visual images, and perceived helpfulness of aural components.
\nA chi-square test revealed that participants were more likely to recall earthquake intensity level correctly when the message included a numerical representation of intensity (χ2 = 78.049, df = 7, p < 0.0001). In other words, participants more accurately recalled the numeral “7” than the phrase “strong shaking.” Qualitative responses indicated confusion, however, regarding what the number “7” actually means. Some noted that “the number was important,” but many also claimed that “many people don’t known what INTENSITY means.” One respondent wrote, for example, “I assume the 7 means 7 out of 10?” Thus, although respondents could recall seeing the number “7,” many did not know what it meant. Therefore, if a numerical representation is present in the warning message, the message must also somehow indicate its meaning and/or prior instruction may be necessary for it to be truly meaningful/effective.
\nFour of the eight conditions tested included a map indicating the epicenter of the earthquake in relation to well-known California cities and highways and four did not. Participants viewing a message without a map were more likely to recall the earthquake’s location incorrectly or not at all than those viewing a message that included a map (χ2 = 43.831, df = 7, p < 0.0001). Qualitative analysis of open-ended responses confirmed the value of the map. Participants viewing the map reported, for example, that “the map showing the general area of the quake was important” and “the map helped me realize where the earthquake was occurring.” Moreover, some commented about the size of the map saying, “the map was far too small to be useful.” Those viewing a message without a map made queries such as: “Did I miss the location?” Based on these results, then, the prototype messages should include a map and the map should be large enough to see easily via a smart phone app.
\nFour conditions provided countdowns represented numerically and four offered countdowns represented in graphic form. The quantitative analysis revealed no statistically significant differences in terms of message recall or effectiveness. The qualitative analysis of the open-ended responses provided insight as to why. When participants viewed the numerical countdown, some reported that the static image was confusing because it did not actually count down from 6 to 5, 4, 3, 2, and 1. Moreover, participants that viewed conditions that conveyed both the countdown and the intensity in numerical form were confused about the meaning of each one. When participants viewed the graphic countdown, they also indicated confusion due to the fact that it was static and did not actually move as the number of seconds to impact declined. Many commented as this participant did: “I’m not sure what the pie graph was supposed to represent.” Regardless of the version participants viewed, many suggested using a countdown clock (stopwatch image or digital clock face: 06, 05, 04 that actually ticked down with each second). As one participant noted, “a countdown clock would underscore the importance of acting quickly.” Clearly, additional message refinement using an active countdown was warranted.
\nPerceived helpfulness was measured using a Likert-type scale ranging from 1 to 5, where 1 was least helpful and 5 was most helpful. In addition, open-ended responses were collected and analyzed for recurring themes. Perceived helpfulness results were analyzed and reported for visual images and aural components.
\nAn Analysis of Variance test revealed significant differences among conditions. Regarding visuals, messages that did not include maps and numerical intensity indicators were perceived as least helpful (F(7,188) = 7.789, p < 0.0001). These results support previous findings regarding location and intensity indicators.
\nAn Analysis of Variance revealed no significant differences in the perceived helpfulness of the app based on the alert sound or the speaker’s voice. Since this phase one experiment did not examine different alert message sounds or speaker voices, this result is not surprising. The qualitative analysis did reveal several dominant themes, however, regarding aural components that may inform future message design and testing. Regarding the alert sound, for example, participants responded it “was too light and high pitched” and “should also vibrate the phone.” Some also argued “it should be the same as other national emergency radio announcements.” Others contended that it should be the same as the sound used in Japanese earthquake warning messages. Regarding the speaker’s voice, some claimed that recognizing the voice of Lucy Jones provided a sense of credibility. In other words, the voice “has meaning because I recognize it is Dr. Lucy Jones I find her voice compelling and reassuring.” Thus, this qualitative analysis suggests that the familiar voice of a noted expert may be most important for fostering trustworthiness. These preliminary findings support the meta-analysis of hundreds of communication studies drawing similar conclusions that there are, in fact, negligible differences in perceived credibility and effectiveness based on sex and perceived gender [9].
\nThe results of phase one of this research project revealed several findings:
Participants were significantly more likely to recall the location of the earthquake when the app included a map. They also perceived the apps that included a map to be most helpful.
Participants were significantly more likely to recall the intensity level of the earthquake when a numerical indicator was included. However, a qualitative analysis of open-ended responses revealed a great deal of confusion about what this number means.
No significant differences were found among apps that used numerical versus graphical countdown imaging. The qualitative analysis of open-ended responses revealed confusion because neither countdown approach actually counted down by seconds from 6, to 5, 4, 3, 2, and 1. Participants indicated a desire to see the seconds dropping via an image that represents a digital clock-face or stopwatch-type image.
This phase one pilot project did not test different alert sounds or voice commands statistically as the project was already comprised of eight conditions. However, a qualitative analysis of open-ended responses revealed that participants believed the alert sound should be familiar (e.g., similar to the one used in the US for other warning messages or similar to the one being used already in Japan for earthquake warning messages).
Based on these results and input from risk and crisis communication specialists, seismologists, and emergency manager practitioners, the research team moved into phase two of the project. More specifically, the researchers used this information to refine the prototype IDEA model messages down from eight to four conditions and created a control message based on the existing ShakeAlert warning message computer program used by emergency managers throughout the US west coast states at the time.
\nBased on the results of phase one message testing and focused feedback from crisis and risk communication subject matter experts, seismologists, and practitioners, the original eight conditions were reduced to four. These four treatment conditions were manipulated as follows:
Japanese alert sound with numerical intensity display
US alert sound with numerical intensity display
Japanese alert sound with verbal intensity display
US alert sound with verbal intensity display
The map either rotated with the numerical intensity display or with the verbal intensity display. All other elements were the same across the four conditions (map, countdown, action steps).
\nThe demographics for the sample (N = 294) for phase two was 62.5% female and 37.5% male, 88% Caucasian, and age (M = 47.5; SD = 14.04). Regarding socio-economic status, 52% of the sample reported an annual income of $70,000 or more and 32% currently live in southern California. Of the 294 respondents, 133 provided comments in response to the prompt: “Please provide any additional feedback you believe would be helpful concerning the quality of the app.” Key findings from this round of message testing focus on perceived quality of the app overall, as well as intensity (verbal/numerical), location (map), and behavioral intentions (drop/take cover/hold on).
\nA series of stepwise regression analyses were conducted to examine the research question about perceived quality of the app. The single item asking about the quality of the app used a five-point Likert type response scale (1 = very effective to 5 = not effective). Overall, 75% of the participants across conditions rated the app as “effective” or “very effective” and only 2% rated the app as “not effective.” On the first block, demographic variables were entered in order to account for any variance attributable to respondent characteristics. These included sex, age, race/ethnicity, and income. The second predictor block included these variables, as well as experimental condition. The examination focused on significant models and predictors, as well as potential improvements based on the addition of experimental condition.
\nThe results for the first predictor block indicate a significant model, F(4, 223) = 6.775, p < 0.001. R2 = 0.108. Of the demographic variables only sex β = −249 p < 0.000, and age β = −175 p < 0.01 were predictive of ratings of app quality. When experimental condition was added to the predictor block a significant model was also produced, F(5, 222) = 4.32, p < 0.001, R2 = 0.112. However, the change in variance accounted for was not significant ΛR2 = 0.004. Of the variables in the predictor block, only sex β = −245 p < 0.000, and age β = −176 p < 0.01 were predictive of ratings of app quality.
\nA t-test was conducted for the variables of sex and overall quality across conditions. Women (M = 1.73 SD = 0.81) were more likely than men (M = 2.14, SD = 1.04) to rate the app as being of high quality t(2) = 3.592, p < .001. Sex differences in perceptions of app quality were then broken down by each condition. Differences were found for condition 2, where women (M = 1.61, SD = 1.12) reported higher perceptions of app quality than men (M = 2.30. SD = .74) t(2) = 2.696, p < 0.01, and condition 5 where women (M = 1.70, SD = 0.65) reported higher perceptions of quality than men (M = 2.19, SD = 1.01) t(2) = 2.190, p < 0.05.
\nPerhaps most important here is that participants in all treatment conditions rated the quality of the app as high. Since all treatment conditions used similar content based on the IDEA model (i.e., alert sound, oral and visual countdown, intensity level, map, actionable instructions), it seems the appropriate content is being included. Moreover, a thematic analysis of the open-ended responses revealed that those viewing the control (ShakeAlert) condition were “overwhelmed by the visuals” and wanted to see and hear directions to “duck, cover, and hold on.” These themes suggest that (a) too much information, although accurate, can defeat the purpose of the warning and (b) specific action steps need to be included. In addition to perceived quality of the app, the researchers sought to learn more regarding numerical versus verbal intensity displays, the effect of the map in location cognition (proximity), and behavioral intentions to take appropriate self-protective actions.
\nKey findings from this round of message testing regarding intensity are as follows. First, there were no significant differences among conditions regarding intensity. However, an exploration of descriptive statistics shed additional light on this issue. When asked “how important is it to know the kind of shaking,” 76–87% reported it as very important across all conditions. Moreover, 77–85% of the respondents across conditions answered correctly (i.e., 10 seconds or less) when asked when the shaking would begin.
\nImportant findings emerged when asked what kind of shaking would occur. It is encouraging to note that 77–93% of the respondents reported correctly that very strong shaking was going to occur. The researchers placed a screen shot before entering the survey that summarized the meaning of the numerical intensity numbers. When respondents that viewed the verbal intensity display were asked about the numerical intensity level (8), only 15 and 22.4% recalled the correct number. Of the respondents that viewed the numerical intensity display, 69 and 80% recalled the correct number. Of the respondents that viewed the control (ShakeAlert) message, only 35.5% recalled the correct number. This low percentage may be impacted by the amount of detailed information being displayed in the control message. So much information may be difficult to process in 10 seconds or less and, thus, may result in misunderstanding.
\nSubsequently, when asked how well they understand the meaning of intensity level numbers, 48.4 and 38.8% of those viewing the verbal display marked “very well.” Respondents that viewed the numerical intensity display reported knowledge comprehension of “very well” at 56.7 and 56.5%. Those viewing the control (ShakeAlert) message reported knowing the meaning very well at 45.9%. These results suggest the verbal intensity display is more meaningful than the numerical display. These results also suggest that displaying both (as in the control ShakeAlert message) appears to be too much information to process accurately in a short amount of time.
\nAll conditions included a map identifying where the shaking was going to occur. There were no significant differences among the conditions regarding the importance of the map or for accurate location identification. Across conditions, 74–92% reported a map as “important” or “very important.” A somewhat troubling finding, however, was that when asked where the shaking was going to occur, only 33–55% answered correctly (Los Angeles area) across conditions. When the researchers drilled down to include only participants currently living in southern California, the results improved slightly among the four treatment conditions (64–74% correct). However, only 29% of the respondents that viewed the control (ShakeAlert) message answered correctly. Moreover, when asked how helpful the visual images were in conveying information about location, only 27.9–50% said “very helpful” across conditions. However, in all four treatment conditions, respondents reported more preference for the visual images (M = 1.90, SD = 1.82) than those in the control condition (M = 2.26, SD = 1.30) t(2) = −2.106 = p < 0.05. Moreover, a thematic analysis of the open-ended comments revealed a desire for a simple map that merely showing a familiar city with a bullseye target or location flag would be more helpful than one showing both the epicenter and location where shaking will occur. Taken together, these results suggest that a simple map highlighting the location may be more effective than a detailed one showing lots of information.
\nA series of stepwise regression analyses were conducted to examine the research question regarding behavioral intentions. The composite measures were used to assess perceptions of behavioral intentions. The measure for behavioral intentions used nine items with a response scale of 1 = “Very Unlikely” to 5 = “Very Likely.” On the first block, demographic variables were entered in order to account for any variance attributable to respondent characteristics. These included sex, age, race/ethnicity, and income. The second block added experimental condition to these possible predictor variables. The analyses focused on significant models and predictors, as well as possible improvement to the model based on the addition of experimental condition.
\nThe results for the first predictor block did not indicate a significant model, F(4, 227) = 0.989, p = n.s. R2 = 0.017. None of the demographic variables were predictive of behavioral intentions. When experimental condition was added to the predictor block the model did not improve, F(5, 229) = 0.788, p = n.s., R2 = 0.017. None of the variables in the predictor block were predictive of behavioral intentions.
\nThe fact that no significant model stood out as a better predictor for behavioral intentions combined with the descriptive statistics suggest that the including the IDEA model components as we did in each condition may be effective for earthquake early warning messages delivered via a smart phone app. Although the means reported are encouraging, the fact that the pretest self-efficacy (M = 4.44) also may point to a respondent pool comprised of members of a disaster sub-culture that is already pre-disposed to taking appropriate actions for self-protection.
\nSeveral promising conclusions may be drawn from these two rounds of message design and testing. First, a phone APP can be designed in ways that employ the IDEA elements of effective instructional risk and crisis messages for earthquake early warnings in 10 seconds or less. Second, the elements of the IDEA model do appear to positively influence affective (perceived value/importance), cognitive (comprehension), and behavioral (efficacy and intention) learning outcomes.
\nAlso based on these message testing results, however, more honing of some particulars are still warranted. For example, with regard to internalization, the design of the map (proximity) needs to be simplified to ensure accurate comprehension of location. Regarding explanation, it appears that verbal intensity displays are more effective than numerical displays unless a comprehensive educational campaign could be conducted to teach users what the different numbers mean.
\nThe sample for both rounds of message testing was not representative of the entire population in southern California. Additional message testing targeting more representative demographic diversity and marginalized populations is warranted in order to be certain about ultimately launching the most effective warning app.
\nCoronavirus Disease 19 (Covid-19) marked the years 2020 and 2021 with its very fast diffusion rates and severity. With the quick development of vaccines against the disease, the pandemic right now seems to come to an end. Yet, living the last 2 years with a contagious disease has left some serious questions: What is the role of socio–economic determinants in the transmission of an airborne contagious disease like Covid–19? What factors are most influential and make countries more vulnerable to such diseases? What is the role of spatiality in the spread? In this study, we aim to investigate the answers to these questions for Turkey. More specifically, we try to point out the most influential socio–economic factors in the spread of Covid-19 in Turkey in a spatial setting.
The first Covid-19 case is confirmed in Turkey on 11th March 2020 in İstanbul. It spread quickly all over the country. To limit its transmission among the Turkish provinces, similar strategies to other countries, such as travel restrictions and partial curfews, were applied in the initial days. Yet, in time, it has become clear that every country has its own dynamics that limit the effectiveness of precautions against the Covid-19. For example, [1] find that the extreme poverty level is an important determinant in the national performance of low– and middle–income countries, since it determines the ability of social distancing. They also note that the disadvantaged share of the population in terms of socio–economic status is more vulnerable to contagious diseases. Therefore, each country must be assessed individually to understand its needs and to be prepared for future diseases. Analyzing the spread of the Covid-19 and the socio–economic determinants behind is important to be ready for any country as well as Turkey.
The ties between the socio–economic status in the spread of Covid-19 were discussed previously in the literature. These studies mainly focus on mainland China [2, 3] and the USA [4, 5]. Some of them compare the national performances of many countries based on the socio–economic variables, (e.g., [6, 7, 8]). Yet, as [4] clearly state, “
Ref. [11] emphasize the role of spatiality in the analysis of contagious diseases by stating that “
Although the importance of location in the transmission process of such diseases besides the other risk factors is mentioned heavily in the literature, studies considering geography in the Covid-19 incidence rates are scarce and they mostly make a choice between the spatial autoregressive model (SAR) and spatial error model (SEM). [15], for example, attempts to determine the socio-economic and region-specific in the Covid-19 transmission in German counties with a choice between SAR and SEM specifications. [16] examine the local transmission of Covid-19 cases in the USA. Again, they made a selection between SAR and SEM based on the Lagrange Multiplier (LM) tests. [17] employ SAR, SEM, and SAC models to detect the Covid-19 period prevalence in the US counties. [4] consider several demographic factors and income as well as air pollution and health-related variables in order to explain the spread of Covid-19 in the US states. They also employ a SAR model. [18] use the number of confirmed new cases in mainland China as the dependent variable where the recovered cases and the rate of deaths are the explanatory variables in a spatial panel setting. He compares SEM and SAR models, but cannot show spatiality in the explanation of the rate of new cases. He concludes that the spatial lag of X (SLX) model fits the nature of local spillovers in this association for China.
The situation for the scarce studies that consider the spread of Covid-19 in Turkey from a spatial perspective is parallel to the world literature. [8] provides an exploratory spatial analysis with different weight matrices for Turkish Covid-19 cases and deaths in which high spatial autocorrelation is detected particularly for major Turkish provinces. Similarly, [19] use Moran I and Local Indicator Spatial Association (LISA) statistics to determine the hot and cold spots among Turkish provinces. [20] examine the effects of a group of socio–economic determinants as well as climate–based variables on the number of Covid-19 cases with SEM and SAR specifications. [21] looks at the relationship between centrality in terms of trade, transportation, and health and the number of cases in a Turkish province while considering other socioeconomic factors as control variables. For this aim, he employs SAR and SAC models. [22] use the impact of population density, elderly dependency ratio, Gross Domestic Product (GDP) per capita, literacy rate, and health capacity variables to explain the diffusion of Covid-19 in Turkey with a SAR model. They find global spillovers and significant coefficients for population density and elderly dependency ratio while explaining the increase in the Covid-19 cases.
With this study, we also contribute to the scarce literature on Covid-19 studies in Turkey with a spatial perspective. One of the novelties of this paper comes from the spatial model it adopts. Unlike the previous spatial studies on Covid-19 diffusion, we argue that a spatial Durbin model (SDM) must be the first model to adopt for the analysis. The SDM approach is well known for containing both the global and local spillovers at the same time, which is a feature of the Covid-19 pandemic. In fact, when the best describing model is unknown, [23] suggests using SDM as a starting point as well. As a result, we start our analysis with an SDM setting to detect the local and global spillovers in the diffusion of Covid-19 cases across 81 Turkish provinces. Different from the existing studies, we use the vaccination rates and sub–indicators of Life Index in Provinces by the Turkish Statistical Institute (TSI) as the explanatory variables. Life Index in Provinces report includes 41 sub–indicators about income, work life, safety, housing, environment, social life, access to infrastructure services, education, life satisfaction, and civic engagement. By using these sub–indicators, we believe that every aspect of socioeconomic status in Turkish provinces, from per km2 green area to health capacity, can be taken into account. Hence, an exhaustive list of variables that have the potential to impact the spread of Covid-19 is considered. Controlling the vaccination rates also allows us to detect its role among other variables and its impact on the spread of the disease. By doing so, we are able to contribute to the very limited literature on Covid-19 vaccine hesitancy.
To the extent of our knowledge, a similar study to our setting that examines the spread of Covid-19 in Turkey belongs to [24]. He employs 11 leading indicators of the Life Index in Provinces report, not the sub–indicators as well as other socioeconomic and environmental variables such as GDP, household size, age, air quality, humidity, and average temperature. Although this study also mentions the spatial distribution of Covid-19 cases in Turkey and benefits from some spatial maps, the main analysis method is Ordinary Least–Squares (OLS), not spatial models. By using spatial analysis methods with an exhaustive set of socioeconomic indicators, we believe that our study closes an important gap in the literature.
Our results indicate no significant global impacts in the spread of Covid-19 cases across Turkey, but significant local interactions. We show that vaccination in a given province decreases the total number of cases per hundred thousand people in the same province, but increases the Covid-19 cases in the neighboring province. This seemingly puzzling finding is a result of vaccine hesitancy toward Covid-19 vaccines. The “
Based on the findings of this study, we can suggest that the usage of clear communication channels with society has vital importance in fighting against infectious diseases. In this way, it is possible to correct the misperceptions both about the nature of the disease and the vaccinations. Overconfidence about the health status and vaccine hesitancy might increase the overall number of cases, so the burden on the health care system.
The rest of the study continues with an explanation of the data and methodology utilized. The next section presents our findings. The last section concludes with the policy suggestions to the Turkish authorities for the next pandemics.
This study uses the total number of confirmed COVID-19 cases per 100,000 population from 81 Turkish provinces as the dependent variable. This data is publicly available and reported as weekly averages by the Turkish Ministry of Health.
To be able to determine which explanatory variables might be important in the spread of Covid-19, we examine thoroughly the previous literature that applies both a spatial and non-spatial analysis. [25] argue economic variables like wealth or income are the main drivers of the person-to-person spread of infectious diseases such as COVID-19. [26] demonstrate that low literacy has been influential in the spread of the disease. [17, 27] find that age is effective on the spread of COVID-19 cases. Population and population density were also noted as significant variables by [15, 25, 28, 29]. The number of doctors and the number of hospital beds are considered important factors by [3, 25, 26] because their availability has the potential to draw more COVID-19 patients to the area. Living in an urban vs. rural area might be another determinant in the spread of cases as noted by [25, 29]. [15] also considers household size as a factor. Social life indicators and average space available per household are used by [25].
We proxy the socioeconomic and health status of each province that is noted in the literature by using the Life Index in Provinces provided by the Turkish Statistical Institute in 2016. This index is produced based on the approach of the OECD Better Life Index. The aim of the Life Index in Provinces is to compare the well–being and living quality of Turkish provinces as well as their economic status. To do so, 11 leading indicators and 41 sub–indicators that include both objective and subjective aspects of life are created. These indicators include income, work life, safety, housing, environment, social life, access to infrastructure services, education, life satisfaction, and civic engagement dimensions. Based on the previous literature, we select explanatory variables among the 41 sub–indicators. The dimensions that can affect the spread of Covid-19 but are not captured by the Life Index in Provinces, such as median age, percentage of individuals 65 years old and above, or population density are also added to the analysis.
Besides the socio–economic factors, the vaccine uptake decision of societies is a crucial weapon against the spread of Covid-19. Therefore, we use the vaccination rates for individuals 18 years old and above for each province as a control variable in the models.
A summary of explanatory variables that are employed in this analysis and the data sources are reported in Table 1.
Variable | Proxy | Source |
---|---|---|
COVID-19 variables | Total number of cases per 100,000 population by Turkish provinces | Turkish Ministry of Health (weekly) |
Percentage of 18+ population vaccinated against COVID-19 at least once by Turkish provinces | Turkish Ministry of Health (daily) | |
Housing Conditions | Number of rooms per person | Life Index in Provinces by Turkish Statistical Institute (2016) |
The household size in Turkish provinces | Turkish Statistical Institute (2020) | |
Work Life | Employment Rate | Life Index in Provinces by Turkish Statistical Institute (2016) |
Unemployment Rate | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Average Daily Earnings | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Income and Wealth | Percentage of Households in middle and higher Income Groups | Life Index in Provinces by Turkish Statistical Institute (2016) |
Percentage of Households declaring to fail on meeting basic needs | Life Index in Provinces by Turkish Statistical Institute (2016) | |
GDP per capita by Turkish provinces | Turkish Statistical Institute (2013) | |
Health | Infant Mortality Rate | Life Index in Provinces by Turkish Statistical Institute (2016) |
Life Expectancy at Birth | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Satisfaction Rate with Health Status | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Health Capacity Index | Turkish Ministry of Health, Health Statistics (2018) | |
Education | Percentage of higher education graduates | Life Index in Provinces by Turkish Statistical Institute (2016) |
Safety | Murder Rate | Life Index in Provinces by Turkish Statistical Institute (2016) |
Percentage of people feeling safe when walking alone at night | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Civic engagement | Voter turnout at local administrations | Life Index in Provinces by Turkish Statistical Institute (2016) |
Rate of membership to political parties | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Percentage of persons interested in union/association activities | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Access to Infrastructure Services | Number of internet subscriptions (per hundred persons) | Life Index in Provinces by Turkish Statistical Institute (2016) |
Social life | Number of cinema and theater audiences (per hundred persons) | Life Index in Provinces by Turkish Statistical Institute (2016) |
Shopping mall area per thousand people (m2) | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Satisfaction rate with social relations | Life Index in Provinces by Turkish Statistical Institute (2016) | |
Median Age | Median of individuals’ age in Turkish provinces | Turkish Statistical Institute (2020) |
Age 65+ | Percentage of population over 65 + by Turkish provinces | Turkish Statistical Institute (2020) |
Population | Population density of Turkish provinces | Turkish Statistical Institute (2019) |
Socioeconomic and Covid–19 related variables and the data sources.
The data period is determined by the announcement periods of the Turkish Ministry of Health. Vaccination rates started to be announced at the province level on 04.07.2021 on a daily basis. The total number of cases per 100,000 population is announced weekly. Therefore, we consider the average total number of cases and vaccination rates for July 2021 in this analysis.
A standard OLS model is often estimated as a reference for the following spatial models. This study employs the same starting point. To understand the effect of location on the Covid-19 cases, many studies employ SAR and SEM specifications. [2] note that the SAR model will show how the infection burden in a location is affected by the infection burden in the neighboring locations. SEM is used to understand whether the OLS residuals are correlated to residuals of the neighboring locations. In the lines of [2, 3] also consider a SAC model. They argue that since the SAC model contains a spatial lag and a spatial error term, it can be seen as a combination of these two.
In fact, the spatial model family has a large set of approaches1, and model selection is a crucial part of its applications. [4] argues that this selection must be based on the spillover type that the economic theory points out. Unlike [2]‘s suggestion, [4] stresses that the SAC model is not the linear combination of SAR and SEM approaches. Not considering the spillover types in the selection of appropriate spatial models leads us to the identification problem noted in [5].
[6] state that the locations that are closer to the center of the pandemic are affected more quickly than the distant ones. However, besides geographical proximity, Covid-19 can spread easily when the locations are connected on a network, such as traveling. It means that both global and local spillovers exist in the diffusion of infectious diseases. We argue in this paper that this nature of Covid-19 can be best captured with an SDM approach. [7] also recommends using SDM as a departure point, when the true data generating process, as in the case of Covid-19, is unknown. SDM will also give the linear combination of SAR and SEM specifications [4], as intended by [2, 3].
The OLS model that is used as a benchmark is presented in Eq. (1).
where
The SDM specification that is used in this paper is shown in Eq. (2).
In Eq. (2), the dependent and the explanatory variables are the same as the OLS model defined in Eq. (1). However, here, we scale both the dependent and explanatory variables with a spatial weight matrix (W). The coefficient
Our model selection process follows [7] and we also compare our results with SAR and SLX specifications. The SAR and SLX models are shown in Eq. (3) and Eq. (4) respectively.
The spatial weight matrix used throughout all these models is the same. The elements of W take the value of 1 if two Turkish provinces are neighbors, and zero otherwise.
First, we examine the spatial variation of the total number of cases in Turkey. The spread of Covid-19 cases across Turkish provinces is shown in Figure 1.
The variation of Covid-19 cases across provinces in Turkey in July 2021.
The map in Figure 1 demonstrates that there are regional variations in the diffusion of Covid-19 cases. The total number of confirmed cases increases from west to east of Turkey. We also consider the four main regions of Turkey and statistically compare the average cases in these regions. These regions are defined as follows:
We begin our analysis with the classical OLS model. By excluding the insignificant variables at the 10% level, we refine the model and obtain the ultimate model. We check the OLS assumptions. We find heteroskedasticity in our main model which might be a result of spatial dependency.
As explained before, since the association between the total number of cases and the various socioeconomic variables is not well discussed in the previous literature, we start with an SDM specification to avoid the omitted variable problem [23], which is also the linear combination of SAR and SEM specifications [30]. However, the SDM specification does not show significant results. The LR tests comparing SDM vs. OLS and SAR vs. OLS cannot reject the null hypothesis of no significant global interactions. The lack of significant global spillovers indicates that the burden of the disease at one location is not affected by the burden of the disease in the neighboring locations. Yet, the LR test for the coefficients of local interactions in the SDM specification is significant at the 1% level (LR test is 52.5983, and the p–value is 0.0015). That is to say, although no global impacts can be detected in the transmission process of Covid-19 cases in Turkey, geography still matters in the form of local interactions. The socioeconomic features of neighboring provinces are influential on the spread of Covid-19 in a given province. This finding is in line with the study by [18] in which an SLX model is found appropriate to model the new cases in mainland China. Therefore, following [23], we continue our analysis with an SLX model. The final SLX model and the OLS model as a benchmark are shown in Table 2.
(1) | (2) | |
---|---|---|
Final OLS Model | Final SLX Model | |
Vaccine Rate | −1.5737*** | −1.3693** |
(0.5605) | (0.5926) | |
Membership to Political Parties | 2.0558 | 3.2805** |
(1.5622) | (1.5043) | |
satisfaction rate with social relations | −2.1859 | −2.2772*** |
(1.6857) | (0.7206) | |
satisfaction rate with health status | 3.4398 | 3.3891** |
(2.6869) | (1.6631) | |
Constant | −21.0895 | −26.1843 |
(117.8685) | (105.4470) | |
W*Vaccine Rate | 4.9654*** | |
(1.7096) | ||
W* Median Age | −10.2514*** | |
(3.4318) | ||
AIC | 870.386 | 874.219 |
Adjusted R2 | 0.2341 | |
Number of Observations | 81 | 81 |
The impact of socioeconomic variables on the total cases of Covid-19: OLS and SLX models.
Vaccination is clearly the strongest weapon in the fight against Covid-19. The findings from Table 2 also confirm this situation and reveal that the vaccination rate and the total number of cases are significantly and negatively related. Interestingly, it is found that the effect of vaccination rates in the neighboring provinces is positive and significant. That is, the increased rates of vaccination in the neighboring locations cause a growth in the total number of cases in a given province. This result seems puzzling at first, but it can be explained by the vaccine hesitancy concept. Vaccine hesitancy is defined as the “delay in acceptance or refusal of vaccination despite the availability of vaccination services” [31]. [32] state that the vaccine uptake decision of an individual can be dependent on the actions of the neighbors. They call this concept
We also show that as the satisfaction rate with health status increases, the number of total cases also rises in a particular province. This finding can be attributed to the fact that Covid-19 is mostly perceived as an older people’s disease or only dangerous for people with co–morbidities. To fight this perception, World Health Organization (WHO) made many announcements, including the one that the Chief of WHO explained that “
The rate of membership to political parties is an indicator of civic engagement. As this variable has a higher rate, the social relations, and connections increase as well. This would make it difficult to keep the social distance and adapt to “stay at home” calls. Our findings in Table 2 confirm this result and demonstrate a positive effect of this variable on the total number of cases.
Median age, itself, is not a determinant of the spread of Covid-19 cases across Turkish provinces. However, the median age of the neighbors negatively impacts the number of cases in a given province. This finding is in line with [15]. He notes that the increase in the median age of neighbors reduces the social interactions with the given state and traveling, so less spread has occurred.
The satisfaction rate with social relations is a proxy for social life. Our results indicate that the higher values of this variable are related to a lower level of total cases. It seems that people who are more satisfied with their social life are most likely to keep their social distance and less engaged with many people. This finding might be explained by the existence of video–calls and other telecommunication methods. Individuals may meet their social needs via the internet and stay at home at the same time.
We cannot show any significant effect of housing conditions, work life, income and wealth, or health indicators other than health status, education, safety, and access to infrastructure services, however.
The results of this paper once more emphasize the importance of vaccinations in order to control the number of cases. In the case of such infectious diseases, governments must use clear communication channels with society to avoid misperceptions about the nature of the disease or the precautions to avoid further spread. Our findings show that over–confidence about the individual health status and vaccine hesitancy increase the number of total cases, so the burden on the health care system.
This study employs an exhaustive set of socioeconomic variables and vaccination rates to detect their roles in the spread of Covid-19 in Turkey in a spatial setting. Province-level data allows us to detect the existence of spatiality as well. We cannot detect any global interactions in the diffusion process, so the number of infected people at one location does not bring an extra infection burden to the neighboring locations. Yet, our findings show that local interactions in terms of vaccination rates and median age play an important role in the increase in the total number of cases. Increased vaccination rates in the neighboring provinces also increase the total number of cases in a given province. This result can be explained by the vaccine hesitancy toward the Covid-19 vaccine. We also find evidence that people that are more satisfied with their health status are more likely to catch the disease and increase the total number of cases. To fight the misperceptions about the nature of the disease and the vaccination procedure, the Turkish government must adopt a clear–communication policy and actively work for individuals to access reliable information.
"Open access contributes to scientific excellence and integrity. It opens up research results to wider analysis. It allows research results to be reused for new discoveries. And it enables the multi-disciplinary research that is needed to solve global 21st century problems. Open access connects science with society. It allows the public to engage with research. To go behind the headlines. And look at the scientific evidence. And it enables policy makers to draw on innovative solutions to societal challenges".
\n\nCarlos Moedas, the European Commissioner for Research Science and Innovation at the STM Annual Frankfurt Conference, October 2016.
",metaTitle:"About Open Access",metaDescription:"Open access contributes to scientific excellence and integrity. It opens up research results to wider analysis. It allows research results to be reused for new discoveries. And it enables the multi-disciplinary research that is needed to solve global 21st century problems. Open access connects science with society. It allows the public to engage with research. To go behind the headlines. And look at the scientific evidence. And it enables policy makers to draw on innovative solutions to societal challenges.\n\nCarlos Moedas, the European Commissioner for Research Science and Innovation at the STM Annual Frankfurt Conference, October 2016.",metaKeywords:null,canonicalURL:"about-open-access",contentRaw:'[{"type":"htmlEditorComponent","content":"The Open Access publishing movement started in the early 2000s when academic leaders from around the world participated in the formation of the Budapest Initiative. They developed recommendations for an Open Access publishing process, “which has worked for the past decade to provide the public with unrestricted, free access to scholarly research—much of which is publicly funded. Making the research publicly available to everyone—free of charge and without most copyright and licensing restrictions—will accelerate scientific research efforts and allow authors to reach a larger number of readers” (reference: http://www.budapestopenaccessinitiative.org)
\\n\\nIntechOpen’s co-founders, both scientists themselves, created the company while undertaking research in robotics at Vienna University. Their goal was to spread research freely “for scientists, by scientists’ to the rest of the world via the Open Access publishing model. The company soon became a signatory of the Budapest Initiative, which currently has more than 1000 supporting organizations worldwide, ranging from universities to funders.
\\n\\nAt IntechOpen today, we are still as committed to working with organizations and people who care about scientific discovery, to putting the academic needs of the scientific community first, and to providing an Open Access environment where scientists can maximize their contribution to scientific advancement. By opening up access to the world’s scientific research articles and book chapters, we aim to facilitate greater opportunity for collaboration, scientific discovery and progress. We subscribe wholeheartedly to the Open Access definition:
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The Open Access publishing movement started in the early 2000s when academic leaders from around the world participated in the formation of the Budapest Initiative. They developed recommendations for an Open Access publishing process, “which has worked for the past decade to provide the public with unrestricted, free access to scholarly research—much of which is publicly funded. Making the research publicly available to everyone—free of charge and without most copyright and licensing restrictions—will accelerate scientific research efforts and allow authors to reach a larger number of readers” (reference: http://www.budapestopenaccessinitiative.org)
\n\nIntechOpen’s co-founders, both scientists themselves, created the company while undertaking research in robotics at Vienna University. Their goal was to spread research freely “for scientists, by scientists’ to the rest of the world via the Open Access publishing model. The company soon became a signatory of the Budapest Initiative, which currently has more than 1000 supporting organizations worldwide, ranging from universities to funders.
\n\nAt IntechOpen today, we are still as committed to working with organizations and people who care about scientific discovery, to putting the academic needs of the scientific community first, and to providing an Open Access environment where scientists can maximize their contribution to scientific advancement. By opening up access to the world’s scientific research articles and book chapters, we aim to facilitate greater opportunity for collaboration, scientific discovery and progress. We subscribe wholeheartedly to the Open Access definition:
\n\n“By “open access” to [peer-reviewed research literature], we mean its free availability on the public internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself. The only constraint on reproduction and distribution, and the only role for copyright in this domain, should be to give authors control over the integrity of their work and the right to be properly acknowledged and cited” (reference: http://www.budapestopenaccessinitiative.org)
\n\nOAI-PMH
\n\nAs a firm believer in the wider dissemination of knowledge, IntechOpen supports the Open Access Initiative Protocol for Metadata Harvesting (OAI-PMH Version 2.0). Read more
\n\nLicense
\n\nBook chapters published in edited volumes are distributed under the Creative Commons Attribution 3.0 Unported License (CC BY 3.0). IntechOpen upholds a very flexible Copyright Policy. There is no copyright transfer to the publisher and Authors retain exclusive copyright to their work. All Monographs/Compacts are distributed under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Read more
\n\nPeer Review Policies
\n\nAll scientific works are Peer Reviewed prior to publishing. Read more
\n\nOA Publishing Fees
\n\nThe Open Access publishing model employed by IntechOpen eliminates subscription charges and pay-per-view fees, enabling readers to access research at no cost. In order to sustain operations and keep our publications freely accessible we levy an Open Access Publishing Fee for manuscripts, which helps us cover the costs of editorial work and the production of books. Read more
\n\nDigital Archiving Policy
\n\nIntechOpen is committed to ensuring the long-term preservation and the availability of all scholarly research we publish. We employ a variety of means to enable us to deliver on our commitments to the scientific community. Apart from preservation by the Croatian National Library (for publications prior to April 18, 2018) and the British Library (for publications after April 18, 2018), our entire catalogue is preserved in the CLOCKSS archive.
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Liposuction is a procedure to improve the body contour and not a surgery to reduce weight, although recently people who have failed in their plans to lose weight look at liposuction as a means to contour their body figure. Tumescent liposuction of large volumes requires a meticulous selection of each patient; their preoperative evaluation and perioperative management are essential to obtain the expected results. The various techniques of general anesthesia are the most recommended and should be monitored in the usual way, as well as monitoring the total doses of infiltrated local anesthetics to avoid systemic toxicity. The management of intravenous fluids is controversial, but the current trend is the restricted use of hydrosaline solutions. The most feared complications are deep vein thrombosis, pulmonary thromboembolism, fat embolism, lung edema, hypothermia, infections and even death. 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It has a higher prevalence of refractory seizures when compared to those with idiopathic epilepsy (40 vs. 26%). These patients are usually treated with multiple anti-epileptic drugs, yet the total number of which used is inversely proportional to their efficacy. Moreover, these children may have significantly worse behavioural problems and can result in substantial cognitive impairments when older. Luckily, the number of cryptogenic epilepsy cases is diminishing due to better diagnostic abilities in recent years. We aim to divide this chapter into three parts. First, we hope to discuss our working algorithm and explain the use and advantages of different imaging modalities including high-field 3-Tesla MRI with morphological analysis for accurate localisation of the epileptogenic foci. We shall then elaborate the concept of the epileptogenic circuit and explore the selection criteria for more invasive approaches, such as depth electrodes and SEEG. Last but not the least, we aim to discuss the surgical treatments, including VNS and DBS, and their outcomes in these patients.",book:{id:"11585",title:"Epilepsy - Seizures Without Triggers",coverURL:"https://cdn.intechopen.com/books/images_new/11585.jpg"},signatures:"Joyce Shuk Wan Chow and Tak Lap Poon"},{id:"82407",title:"Current Diagnostic Tests for Dry Eye Disease in Sjögren’s Syndrome",slug:"current-diagnostic-tests-for-dry-eye-disease-in-sj-gren-s-syndrome",totalDownloads:1,totalDimensionsCites:null,doi:"10.5772/intechopen.103671",abstract:"Sjogren’s syndrome (Sicca Syndrome) is mainly characterized by the presence of dry eye disease (DED). 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The newer evaluations that provide the greatest diagnostic value for Sjogren’s syndrome are: noninvasive keratograph tear rupture time (NIKBUT), tear meniscus height (TMH), Schirmer’s test, meibography, ocular surface disease index (OSDI), Vital stains of the ocular surface, Matrix Metalloproteinase 9 (MMP-9), Tear osmolarity (TearLab); all of these are important complements to the existing tests, which, although less objective, are not substitutable.",book:{id:"11702",title:"Eye Diseases - Recent Advances, New Perspectives and Therapeutic Options",coverURL:"https://cdn.intechopen.com/books/images_new/11702.jpg"},signatures:"María del Rosario Sánchez Valerio"},{id:"82987",title:"Health of Trans People in Paraguay",slug:"health-of-trans-people-in-paraguay",totalDownloads:0,totalDimensionsCites:0,doi:"10.5772/intechopen.106488",abstract:"Trans care is not taught in conventional medical education programs, and very few doctors have the knowledge and comfort level to do so. A theoretical design study was carried out using the bibliographic review method, which allowed to provide a systematic framework of products in terms of scientific publications and official publications on the health of transgender people. In the Paraguayan context, it is recognized that sex work is the main economic activity of 86% of trans people, which although it is a job that is not punished in Paraguay, but neither is it recognized or regulated by law, although in Paraguay, numerous international instruments for the protection of human rights have been ratified, by which it is obliged to adopt measures to guarantee the sexual and reproductive health of all people and nondiscrimination based on sex, sexual orientation, and gender identity.",book:{id:"11228",title:"Transgender Health: Advances and New Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11228.jpg"},signatures:"Carlos Miguel Rios-González"},{id:"82989",title:"Human Sperm Vitrification: Review of Recent Progress",slug:"human-sperm-vitrification-review-of-recent-progress",totalDownloads:1,totalDimensionsCites:0,doi:"10.5772/intechopen.106267",abstract:"Sperm vitrification has been used in the field of assisted reproductive technology (ART) for years and has resulted in many healthy live births. Compared to the conventional sperm slow freezing method, vitrification is simpler, quicker, and less expensive, and some vitrification methods are also cryoprotectant free, which has the potential to become an alternative cryopreservation method for human sperm. Human sperm vitrification has been the most commonly used and valuable way to preserve the fertility of males with small numbers of spermatozoa. Recently, new sperm vitrification devices have been developed to help improve volume control. Direct contact during the vitrification process with liquid nitrogen increases the risk of cross-contamination. New strategies have been implemented to minimize the contamination risk. Depending on the variety of semen parameters and patients’ purposes at ART clinics, specific sperm cryopreservation approaches should be personalized to achieve the optimal results for each case.",book:{id:"11735",title:"Embryology Update",coverURL:"https://cdn.intechopen.com/books/images_new/11735.jpg"},signatures:"Feng Gao"},{id:"82976",title:"Mesothelioma: Overview of Technical, Immunochemical and Pathomorphological Diagnosing Aspects",slug:"mesothelioma-overview-of-technical-immunochemical-and-pathomorphological-diagnosing-aspects",totalDownloads:0,totalDimensionsCites:0,doi:"10.5772/intechopen.106570",abstract:"For the clinicians with non-pathology background, first encountering the patients with pleural or peritoneal effusions, mesothelioma is only one statistically rare but clinically significant option of many differential diagnoses. This review aims to help the clinicians and broad life science audiences to understand step by step the possibilities and shortcomings of pathological diagnosing of mesothelioma, including the basic technical requirements. The first cytomorphology evaluation of pleural and peritoneal effusions in routinely stained smears enables in most cases only to identify cells suspicious for malignancy. The recent guidelines of epithelioid mesothelioma cytologic diagnosis and reporting emphasize immunochemistry (IC) in the cell blocks is mandatory whenever a diagnosis of malignancy is clinically entertained and/or cytologically suspected. The IC workup is challenging, since there is no fixed antibody panel, but multiple questions must be solved, such as 1) confirm the mesothelial or epithelial origin of isolated atypical cells and cell clusters; 2) delineate their benign or malignant nature; and 3) discriminate mesothelioma from other malignancies and metastatic disease. The rationale of the most widely clinically used IC markers is given and illustrated by the examples. The final confirmation of mesothelioma diagnosis and establishing its subtype and grade is possible only in the histological samples.",book:{id:"10831",title:"Mesothelioma - Diagnostics, Treatment and Basic Research",coverURL:"https://cdn.intechopen.com/books/images_new/10831.jpg"},signatures:"Ave Minajeva and Diana Saranova"},{id:"82974",title:"Canine Glioma as a Model for Human Glioblastoma",slug:"canine-glioma-as-a-model-for-human-glioblastoma",totalDownloads:2,totalDimensionsCites:0,doi:"10.5772/intechopen.106464",abstract:"Glioblastoma, a high-grade diffuse glioma, carries a poor clinical prognosis despite decades of extensive research on the genetic and molecular features of disease and investigation of experimental therapeutics. Because spontaneous canine glioma and human glioblastoma share many clinicopathologic characteristics, recent efforts have focused on utilizing companion dogs as a preclinical model for both research and therapeutic development. A detailed investigation of the canine disease, with particular attention to the genetic and molecular profile, is important in order to allow translation of specific clinical findings from canines to humans and vice versa. In this chapter, we investigate the most common genetic, molecular, and epigenetic alterations associated with canine and human glioma. Appropriate implementation of the canine glioma model may provide valuable information to improve both human and veterinary patient care.",book:{id:"11597",title:"Glioblastoma - Current Evidences",coverURL:"https://cdn.intechopen.com/books/images_new/11597.jpg"},signatures:"Nicole M. Yost and James M. 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The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"23",title:"Education and Human Development",doi:"10.5772/intechopen.100360",issn:null,scope:"
\r\n\tEducation and Human Development is an interdisciplinary research area that aims to shed light on topics related to both learning and development. This Series is intended for researchers, practitioners, and students who are interested in understanding more about these fields and their applications.
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She has been a faculty member at the University of California, Riverside in the School of Education since 2016. Her research focuses on translational studies to explore the reward system in ASD, as well as how anxiety contributes to social challenges in ASD. She also investigates how behavioral interventions affect neural activity, behavior, and school performance in children with ASD. She is also involved in the diagnosis of children with ASD and is a licensed clinical psychologist in California. She is the Assistant Director of the SEARCH Center at UCR and is a faculty member in the Graduate Program in Neuroscience.",institutionString:null,institution:{name:"University of California, Riverside",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:2,paginationItems:[{id:"89",title:"Education",coverUrl:"https://cdn.intechopen.com/series_topics/covers/89.jpg",isOpenForSubmission:!1,annualVolume:null,editor:{id:"260066",title:"Associate Prof.",name:"Michail",middleName:null,surname:"Kalogiannakis",slug:"michail-kalogiannakis",fullName:"Michail Kalogiannakis",profilePictureURL:"https://mts.intechopen.com/storage/users/260066/images/system/260066.jpg",biography:"Michail Kalogiannakis is an Associate Professor of the Department of Preschool Education, University of Crete, and an Associate Tutor at School of Humanities at the Hellenic Open University. He graduated from the Physics Department of the University of Crete and continued his post-graduate studies at the University Paris 7-Denis Diderot (D.E.A. in Didactic of Physics), University Paris 5-René Descartes-Sorbonne (D.E.A. in Science Education) and received his Ph.D. degree at the University Paris 5-René Descartes-Sorbonne (PhD in Science Education). His research interests include science education in early childhood, science teaching and learning, e-learning, the use of ICT in science education, games simulations, and mobile learning. 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She has run and participated in several funded and non-funded projects on the teaching of Science, Social Sciences, and ICT in education. She also has the experience of participating in five Erasmus+ projects.",institutionString:"University of Crete",institution:{name:"University of Crete",institutionURL:null,country:{name:"Greece"}}},editorThree:null},{id:"90",title:"Human Development",coverUrl:"https://cdn.intechopen.com/series_topics/covers/90.jpg",isOpenForSubmission:!0,annualVolume:11974,editor:{id:"191040",title:"Dr.",name:"Tal",middleName:null,surname:"Dotan Ben-Soussan",slug:"tal-dotan-ben-soussan",fullName:"Tal Dotan Ben-Soussan",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBf1QAG/Profile_Picture_2022-03-18T07:56:11.jpg",biography:"Tal Dotan Ben-Soussan, Ph.D., is the director of the Research Institute for Neuroscience, Education and Didactics (RINED) – Paoletti Foundation. 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Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. 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He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null}]},{type:"book",id:"7839",title:"Malaria",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7839.jpg",slug:"malaria",publishedDate:"December 11th 2019",editedByType:"Edited by",bookSignature:"Fyson H. Kasenga",hash:"91cde4582ead884cb0f355a19b67cd56",volumeInSeries:4,fullTitle:"Malaria",editors:[{id:"86725",title:"Dr.",name:"Fyson",middleName:"Hanania",surname:"Kasenga",slug:"fyson-kasenga",fullName:"Fyson Kasenga",profilePictureURL:"https://mts.intechopen.com/storage/users/86725/images/system/86725.jpg",biography:"Dr. Kasenga is a graduate of Tumaini University, Kilimanjaro Christian Medical College, Moshi, Tanzania and Umeå University, Sweden. He obtained a Master’s degree in Public Health and PhD in Public Health and Epidemiology. He has a background in Clinical Medicine and has taken courses at higher diploma levels in public health from University of Transkei, Republic of South Africa, and African Medical and Research Foundation (AMREF) in Nairobi, Kenya. Dr. Kasenga worked in different places in and outside Malawi, and has held various positions, such as Licensed Medical Officer, HIV/AIDS Programme Officer, HIV/AIDS resource person in the International Department of Diakonhjemet College, Oslo, Norway. He also managed an Integrated HIV/AIDS Prevention programme for over 5 years. He is currently working as a Director for the Health Ministries Department of Malawi Union of the Seventh Day Adventist Church. Dr. Kasenga has published over 5 articles on HIV/AIDS issues focusing on Prevention of Mother to Child Transmission of HIV (PMTCT), including a book chapter on HIV testing counseling (currently in press). 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:{name:"Medical University Plovdiv",country:{name:"Bulgaria"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. RELACION DE PONENCIAS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGIA. 10/2014.",institutionString:null,institution:null},{id:"243698",title:"Dr.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:null,institution:null},{id:"7227",title:"Dr.",name:"Hiroaki",middleName:null,surname:"Matsui",slug:"hiroaki-matsui",fullName:"Hiroaki Matsui",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Tokyo",country:{name:"Japan"}}},{id:"312999",title:"Dr.",name:"Bernard O.",middleName:null,surname:"Asimeng",slug:"bernard-o.-asimeng",fullName:"Bernard O. Asimeng",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Ghana",country:{name:"Ghana"}}},{id:"318905",title:"Prof.",name:"Elvis",middleName:"Kwason",surname:"Tiburu",slug:"elvis-tiburu",fullName:"Elvis Tiburu",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Ghana",country:{name:"Ghana"}}},{id:"336193",title:"Dr.",name:"Abdullah",middleName:null,surname:"Alamoudi",slug:"abdullah-alamoudi",fullName:"Abdullah Alamoudi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"318657",title:"MSc.",name:"Isabell",middleName:null,surname:"Steuding",slug:"isabell-steuding",fullName:"Isabell Steuding",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}},{id:"318656",title:"BSc.",name:"Peter",middleName:null,surname:"Kußmann",slug:"peter-kussmann",fullName:"Peter Kußmann",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}}]}},subseries:{item:{id:"3",type:"subseries",title:"Bacterial Infectious Diseases",keywords:"Antibiotics, Biofilm, Antibiotic Resistance, Host-microbiota Relationship, Treatment, Diagnostic Tools",scope:"