The prediction results of 14-class SVM classifier with L1 regularity.
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"10814",leadTitle:null,fullTitle:"Anxiety, Uncertainty, and Resilience During the Pandemic Period - Anthropological and Psychological Perspectives",title:"Anxiety, Uncertainty, and Resilience During the Pandemic Period",subtitle:"Anthropological and Psychological Perspectives",reviewType:"peer-reviewed",abstract:"The COVID-19 pandemic has had adverse effects on many people’s mental and physical health. As such, this book explores research, theories, biopsychosocial perspectives, and intercultural studies about the pandemic with the ultimate goal to promote better quality of life, resilience, and psychological wellbeing of the general population during this period.",isbn:"978-1-83968-126-4",printIsbn:"978-1-83968-119-6",pdfIsbn:"978-1-83968-215-5",doi:"10.5772/intechopen.95017",price:159,priceEur:175,priceUsd:205,slug:"anxiety-uncertainty-and-resilience-during-the-pandemic-period-anthropological-and-psychological-perspectives",numberOfPages:772,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"2db4d2a6638d2c66f7a5741d0f8fe4ae",bookSignature:"Fabio Gabrielli and Floriana Irtelli",publishedDate:"November 3rd 2021",coverURL:"https://cdn.intechopen.com/books/images_new/10814.jpg",numberOfDownloads:17376,numberOfWosCitations:3,numberOfCrossrefCitations:15,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:23,numberOfDimensionsCitationsByBook:0,hasAltmetrics:1,numberOfTotalCitations:41,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"January 28th 2021",dateEndSecondStepPublish:"February 18th 2021",dateEndThirdStepPublish:"April 19th 2021",dateEndFourthStepPublish:"July 8th 2021",dateEndFifthStepPublish:"September 6th 2021",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"259407",title:"Prof.",name:"Fabio",middleName:null,surname:"Gabrielli",slug:"fabio-gabrielli",fullName:"Fabio Gabrielli",profilePictureURL:"https://mts.intechopen.com/storage/users/259407/images/system/259407.jpg",biography:"Dr. Fabio Gabrielli (2015 Nobel Prize nominee) has been Full\nProfessor of Philosophical Anthropology at Ludes University of\nLugano, Switzerland. Currently, he is also working as Professor\nof Philosophy of the Relationship at the School of Management,\nUniversity Jean Monnet, Bari, Italy. He is also a visiting professor, PWSTE, at the University of Jaroslaw, Poland. Dr. Gabrielli\nis a member of the International Scientific Committee of the\nQuantum Paradigms of Psychopathology (QPP) - European section, and a member\nof the Scientific Board of the Aracne Publishing House in Rome for the Neo-existential Anthropology Series. He is the honorary-national president of CCSVI in\nMultiple Sclerosis – ONLUS. Dr. Gabrielli has participated in numerous conferences, seminars, and congresses and has authored many books and journal papers.",institutionString:"Università Lum Jean Monnet",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Università Lum Jean Monnet",institutionURL:null,country:{name:"Italy"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:{id:"174641",title:"Dr.",name:"Floriana",middleName:null,surname:"Irtelli",slug:"floriana-irtelli",fullName:"Floriana Irtelli",profilePictureURL:"https://mts.intechopen.com/storage/users/174641/images/system/174641.jpeg",biography:"Floriana Irtelli is a psychoanalyst/psychotherapist and member of the International Association for Relational Psychoanalysis and Psychotherapy (IARPP) who has been lecturing for several years at the Catholic University of the Sacred Heart, Milan, Italy. She has worked at Fatebenefratelli Hospital in Milan performing research and clinical activities. She is among the authors of several books, including A Fresh Look at Anxiety Disorders and Psychopathy - New Updates on an Old Phenomenon, and has published articles for the Journal of Affective Disorders, Research in Psychotherapy, and the Journal for Psychiatric and Mental Health Nursing. She has participated in numerous conferences, seminars, and congresses. Dr. Irtelli is the sole author of the books Illuminarsi di Ben-essere, Familiar-mente, and Contemporary Perspectives on Relational Wellness.",institutionString:"Catholic University of the Sacred Heart",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"5",totalChapterViews:"0",totalEditedBooks:"4",institution:{name:"Catholic University of the Sacred Heart",institutionURL:null,country:{name:"Italy"}}},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"278",title:"Social Psychology",slug:"social-psychology"}],chapters:[{id:"76565",title:"Introductory Chapter: The Transition from Distress to Acceptance of Human Frailty - Anthropology and Psychology of the Pandemic Era",doi:"10.5772/intechopen.97688",slug:"introductory-chapter-the-transition-from-distress-to-acceptance-of-human-frailty-anthropology-and-ps",totalDownloads:395,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Fabio Gabrielli and Floriana Irtelli",downloadPdfUrl:"/chapter/pdf-download/76565",previewPdfUrl:"/chapter/pdf-preview/76565",authors:[{id:"259407",title:"Prof.",name:"Fabio",surname:"Gabrielli",slug:"fabio-gabrielli",fullName:"Fabio Gabrielli"},{id:"174641",title:"Dr.",name:"Floriana",surname:"Irtelli",slug:"floriana-irtelli",fullName:"Floriana Irtelli"}],corrections:null},{id:"76604",title:"Various Facets of Anxiety during the Pandemic in India - Critical Issues",doi:"10.5772/intechopen.97797",slug:"various-facets-of-anxiety-during-the-pandemic-in-india-critical-issues",totalDownloads:341,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The COVID-19 pandemic has brought on a lot of challenges. Among these challenges, the most pressing causes for concern are mental health issues. Anxiety is one such mental health concern that statistics has shown as increasing since the beginning of the pandemic. Numerous causes have contributed to these rising levels of anxiety. Health related concerns, loss of income, are just some of the many reasons that individuals have attributed their anxiety to. The Indian population has especially seen a massive number of jobs that have been lost, and the first lockdown in April 2020 saw a major domestic migrant crisis. In addition, a number of groups, such as the elderly, women, and the youth have faced anxiety provoking situations of their own. While India is currently facing a second wave exactly a year later, the facets of anxiety to take into consideration are numerous. The chapter looks at various facets of anxiety that have been encountered during the pandemic from an Indian context.",signatures:"Riddhi Laijawala, Sushma Sonavane and Avinash De Sousa",downloadPdfUrl:"/chapter/pdf-download/76604",previewPdfUrl:"/chapter/pdf-preview/76604",authors:[{id:"346560",title:"Prof.",name:"Avinash",surname:"De Sousa",slug:"avinash-de-sousa",fullName:"Avinash De Sousa"},{id:"415357",title:"Prof.",name:"Sushma",surname:"Sonavane",slug:"sushma-sonavane",fullName:"Sushma Sonavane"},{id:"415358",title:"Ms.",name:"Riddhi",surname:"Laijawala",slug:"riddhi-laijawala",fullName:"Riddhi Laijawala"}],corrections:null},{id:"76489",title:"The Impact of COVID-19 Pandemic on Suicidal Behavior",doi:"10.5772/intechopen.97663",slug:"the-impact-of-covid-19-pandemic-on-suicidal-behavior",totalDownloads:483,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"The new type of coronavirus disease (COVID-19), which has affected the whole world and resulted in many people’s death, has also had negative effects on mental health. The measures, restrictions, and quarantine practices taken to control the pandemic have caused psychological, social, and economic problems. In studies conducted to date, it has been stated that anxiety symptoms, depression, severe adaptation, and sleep disorders are observed in people who have lost their relatives due to COVID-19, who were treated with the diagnosis of COVID-19, or who were exposed to intense information pollution related to the pandemic. It is also known that a large number of people lost their jobs due to the pandemic, and unemployment rates increased in countries. Economies and health systems of many countries are under this significant burden. In addition to the increase in the incidence of mental symptoms and disorders associated with COVID-19, growing socioeconomic problems pose a risk for suicide. In studies on the subject, attention is drawn to the rate of suicide that will increase during and after the pandemic, and warnings are given about taking precautions. In this section, the effects of COVID-19 on suicidal behavior will be discussed in light of findings in the literature.",signatures:"Cicek Hocaoglu",downloadPdfUrl:"/chapter/pdf-download/76489",previewPdfUrl:"/chapter/pdf-preview/76489",authors:[{id:"28322",title:"Prof.",name:"Cicek",surname:"Hocaoglu",slug:"cicek-hocaoglu",fullName:"Cicek Hocaoglu"}],corrections:null},{id:"76786",title:"Mental Health Issues during Covid-19 Pandemic in Portuguese Prisons",doi:"10.5772/intechopen.97798",slug:"mental-health-issues-during-covid-19-pandemic-in-portuguese-prisons",totalDownloads:365,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"During imprisonment, inmates face many difficulties to adapt to prison life well depicted in either classical works or recent research. They usually face many struggles related to the lack of contact with their families. For instance, the less the number of prison visits, the higher levels of aggressiveness and, consequently, the lower levels of adaptation. Additionally, this population is already problematic in “normal conditions” of their imprisonment. When facing crisis – such as the Covid-19 pandemic – their mental and emotional conditions become even worst. Inmates may experience higher levels of anxiety and stress due to the uncertain and high-risk circumstances they are all living. In addition, the deprivations of the support from their families, combined with the higher risk they are exposed due to the danger of Covid-19 virus’ contamination, substantially increase their concerns and could contribute to their lack of adjustment. The present chapter refers to the policies implemented by the Portuguese Prison Administration to deal with the Covid-19 pandemic and a provisional balance of its effects after one year of implementation. Besides information regarding inmate’s mental health conditions during pandemic, data on recidivism rates and criminal activity will also be discussed concerning their implication for future penitentiary policies.",signatures:"Rui Abrunhosa Gonçalves and Joana Andrade",downloadPdfUrl:"/chapter/pdf-download/76786",previewPdfUrl:"/chapter/pdf-preview/76786",authors:[{id:"198691",title:"Prof.",name:"Rui",surname:"Abrunhosa Gonçalves",slug:"rui-abrunhosa-goncalves",fullName:"Rui Abrunhosa Gonçalves"},{id:"346577",title:"Dr.",name:"Joana",surname:"Andrade",slug:"joana-andrade",fullName:"Joana Andrade"}],corrections:null},{id:"76734",title:"Athlete Psychological Resilience and Integration with Digital Mental Health Implementation Amid Covid-19",doi:"10.5772/intechopen.97799",slug:"athlete-psychological-resilience-and-integration-with-digital-mental-health-implementation-amid-covi",totalDownloads:361,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:1,abstract:"The current pandemic’s effect on mental health is uncertain with reports of it being largely negative related to loneliness and unemployment. There are different responses to pandemic stress with regards to cultural differences and social environment. Athletes are special in their experience of psychological resilience – there is a trend of positive adjustment to adversity and stress. However, further systematic review is required to confirm these findings along with an athlete-specific psychological resilience instrument. Key themes in relationships include a dichotomous mental health state marked by maladjustment and subsequent resilience, biopsychosocial factors as well as an array of cultural, social and environmental support and demands marked by stressors within and outside of sport. Digital mental health implementation is a logical next step for advancing the construct of athlete psychological resilience towards complementing an effective prevention and early intervention. However, mental health practitioners are grappling with digital mental health in a hybrid model of care. There is a need for converging on methodologies due to the rapid development of digital technologies which have outpaced evaluation of rigorous digital mental health interventions. The functions and implications of human and machine interactions require explainable and responsible implementation for more certain and positive outcomes to arise.",signatures:"Luke Balcombe and Diego De Leo",downloadPdfUrl:"/chapter/pdf-download/76734",previewPdfUrl:"/chapter/pdf-preview/76734",authors:[{id:"38059",title:"Dr.",name:"Diego",surname:"De Leo",slug:"diego-de-leo",fullName:"Diego De Leo"},{id:"346588",title:"Dr.",name:"Luke",surname:"Balcombe",slug:"luke-balcombe",fullName:"Luke Balcombe"}],corrections:null},{id:"77214",title:"The Impact of the COVID-19 Pandemic on the Mental Health of Dentists",doi:"10.5772/intechopen.98591",slug:"the-impact-of-the-covid-19-pandemic-on-the-mental-health-of-dentists",totalDownloads:390,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Since March 2020, the COVID-19 disease has declared a pandemic producing a worldwide containment. For months, many people were subjected to strict social isolation away from family and loved ones to prevent disease transmission, leading to anxiety, fear, and depression. On the other hand, many had to close down their businesses and stop working, resulting in financial issues. Previous studies have reported that pandemics, epidemics, and some diseases can lead to mental disorders such as fear, anxiety, stress, and depression. Among those most affected, healthcare workers (HCWs), especially those on the front line, often develop mental health problems. Although there is data available on the management and care of HCWs, little attention has been paid to the mental health and well-being of dentists during the COVID-19 pandemic. Therefore, this chapter aims to review the impact of the COVID-19 pandemic on dentists’ mental health and mental health-related symptoms. Finally, to recommend specific measures to avoid consequent potential implications for dentists, dental students, and dental patients.",signatures:"Andrea Vergara-Buenaventura and Carmen Castro-Ruiz",downloadPdfUrl:"/chapter/pdf-download/77214",previewPdfUrl:"/chapter/pdf-preview/77214",authors:[{id:"346660",title:"M.Sc.",name:"Andrea",surname:"Vergara-Buenaventura",slug:"andrea-vergara-buenaventura",fullName:"Andrea Vergara-Buenaventura"},{id:"419814",title:"MSc.",name:"Carmen",surname:"Castro-Ruiz",slug:"carmen-castro-ruiz",fullName:"Carmen Castro-Ruiz"}],corrections:null},{id:"76699",title:"Evaluation of Anxiety Disorders and Protective-Risk Factors in Children during Pandemic Process",doi:"10.5772/intechopen.97863",slug:"evaluation-of-anxiety-disorders-and-protective-risk-factors-in-children-during-pandemic-process",totalDownloads:300,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"In this study, the possible negative effects of the pandemic process on children with anxiety disorders or anxiety sensitivity, risk factors and protective factors are discussed from a psychological point of view. In this context, were tried to review risk factors and protective factors by compiling the studies published in the literature on behavioral and emotional disorders observed in children, especially during the pandemic period. As risk factors are discussed mainly personal psychological characteristics such as traumatic experiences etc. As protective factors, personal qualities such as psychological resilience are discussed from a broad perspective. The aim of the chapter is to draw attention to the possible risk factors of children with anxiety disorders during pandemic process and their disadvantageous position resulting from this. At the same time, it is to contribute to the awareness of protective factors and measures that can be taken to strengthen children against this disadvantageous position.",signatures:"İsmail Seçer and Sümeyye Ulaş",downloadPdfUrl:"/chapter/pdf-download/76699",previewPdfUrl:"/chapter/pdf-preview/76699",authors:[{id:"346671",title:"Prof.",name:"İsmail",surname:"Seçer",slug:"ismail-secer",fullName:"İsmail Seçer"},{id:"347163",title:"Mrs.",name:"Sümeyye",surname:"Ulaş",slug:"sumeyye-ulas",fullName:"Sümeyye Ulaş"}],corrections:null},{id:"76902",title:"Anxiety, Uncertainty, and Resilience during the Pandemic: “Re-Directing the Gaze of the Therapeutic Couple”",doi:"10.5772/intechopen.98234",slug:"anxiety-uncertainty-and-resilience-during-the-pandemic-re-directing-the-gaze-of-the-therapeutic-coup",totalDownloads:274,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"The present global pandemic of covid 19 requires many psychotherapists to work at a distance via telephone or the internet. At the same time a considerable number of psychotherapists work with masks while maintaining social distance. This pandemic impact draws our attention to two questions: One is the difference of working within the office vs. working online. Two is how external events impact the individuals socially as well as personally. This chapter explores clinical cases where, even though Covid and its implications imposed a horrible loss and increasing day to day unpredictability on the therapeutic space, the focus of therapy was readjusted thus igniting a process of deeper self-understanding.",signatures:"Eda Arduman",downloadPdfUrl:"/chapter/pdf-download/76902",previewPdfUrl:"/chapter/pdf-preview/76902",authors:[{id:"280312",title:"M.A.",name:"Eda",surname:"Arduman",slug:"eda-arduman",fullName:"Eda Arduman"}],corrections:null},{id:"76845",title:"Psychological Factors Influencing Protective Behaviours during the COVID-19 Pandemic: Capability, Opportunity and Motivation",doi:"10.5772/intechopen.98237",slug:"psychological-factors-influencing-protective-behaviours-during-the-covid-19-pandemic-capability-oppo",totalDownloads:345,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:1,abstract:"This chapter will explore psychological and demographic influences on citizens’ ability to enact protective health behaviours during the COVID-19 pandemic. Such behaviours include social distancing and hygienic practices that have been recommended across the globe to reduce the spread of infection from the coronavirus. Such behaviours represent a seismic change in usual social behaviour and have been particularly difficult to adopt under urgent circumstances. However, human behaviour is the essential driver of the rate and spread of infection. Using evidence from a large-scale longitudinal survey conducted throughout the pandemic in the UK, this chapter explores protective behaviours in relation to the Capability, Opportunity, Motivation-Behaviour (COM-B) model of behaviour change, which presents a framework for understanding the influences on behaviour. We will illustrate how the components of the COM-B model can inform behaviour change interventions and the importance of the role of anxiety in shaping behavioural responses to the pandemic.",signatures:"Jilly Gibson-Miller, Orestis Zavlis, Todd Hartman, Orla McBride, Kate Bennett, Sarah Butter, Liat Levita, Liam Mason, Anton P. Martinez, Ryan McKay, Jamie Murphy, Mark Shevlin, Thomas V.A. Stocks and Richard P. Bentall",downloadPdfUrl:"/chapter/pdf-download/76845",previewPdfUrl:"/chapter/pdf-preview/76845",authors:[{id:"346855",title:"Dr.",name:"Jilly",surname:"Gibson-Miller",slug:"jilly-gibson-miller",fullName:"Jilly Gibson-Miller"},{id:"417299",title:"Mr.",name:"Orestis",surname:"Zavlis",slug:"orestis-zavlis",fullName:"Orestis Zavlis"},{id:"417300",title:"Dr.",name:"Todd",surname:"Hartman",slug:"todd-hartman",fullName:"Todd Hartman"},{id:"417301",title:"Prof.",name:"Kate",surname:"Bennett",slug:"kate-bennett",fullName:"Kate Bennett"},{id:"417302",title:"Dr.",name:"Sarah",surname:"Butter",slug:"sarah-butter",fullName:"Sarah Butter"},{id:"417303",title:"Dr.",name:"Liat",surname:"Levita",slug:"liat-levita",fullName:"Liat Levita"},{id:"417304",title:"Dr.",name:"Liam",surname:"Mason",slug:"liam-mason",fullName:"Liam Mason"},{id:"417305",title:"Mr.",name:"Anton",surname:"Martinez",slug:"anton-martinez",fullName:"Anton Martinez"},{id:"417306",title:"Dr.",name:"Orla",surname:"McBride",slug:"orla-mcbride",fullName:"Orla McBride"},{id:"417307",title:"Dr.",name:"Ryan",surname:"McKay",slug:"ryan-mckay",fullName:"Ryan McKay"},{id:"417308",title:"Prof.",name:"Jamie",surname:"Murphy",slug:"jamie-murphy",fullName:"Jamie Murphy"},{id:"417309",title:"Prof.",name:"Mark",surname:"Shevlin",slug:"mark-shevlin",fullName:"Mark Shevlin"},{id:"417310",title:"Dr.",name:"Thomas V.A.",surname:"Stocks",slug:"thomas-v.a.-stocks",fullName:"Thomas V.A. Stocks"},{id:"417311",title:"Prof.",name:"Richard",surname:"Bentall",slug:"richard-bentall",fullName:"Richard Bentall"}],corrections:null},{id:"77759",title:"A Ray of Hope: Resilience Amidst Uncertainty and Other Psycho-Social Issues during COVID-19 Pandemic",doi:"10.5772/intechopen.99154",slug:"a-ray-of-hope-resilience-amidst-uncertainty-and-other-psycho-social-issues-during-covid-19-pandemic",totalDownloads:248,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The chapter explored the various psycho-social issues that the general masses are still suffering from due to the sudden arrival of COVID-19 pandemic and how the impending uncertainties, regarding almost every aspect of routine life and their own existence, played a major role in moderating the effects of these psycho-social issues. Additionally, amidst all of these uncertainties, how resilience of people whether social, mental or religious helped people in overcoming their different fears and psycho-social issues. The chapter incorporated findings achieved from different samples such as that of students, employees, health workers etc. And the role of resilience throughout the history in helping humankind overcoming such disastrous situations. Moreover, the chapter also tried to incorporate the protective strategies which can be useful in overcoming the prevalent uncertainties that still remain.",signatures:"Kanwar Hamza Shuja, Arfa Mubeen and Shazia Tariq",downloadPdfUrl:"/chapter/pdf-download/77759",previewPdfUrl:"/chapter/pdf-preview/77759",authors:[{id:"286219",title:"Ph.D. Student",name:"Kanwar",surname:"Hamza Shuja",slug:"kanwar-hamza-shuja",fullName:"Kanwar Hamza Shuja"},{id:"424971",title:"Ms.",name:"Arfa",surname:"Mubeen",slug:"arfa-mubeen",fullName:"Arfa Mubeen"},{id:"424972",title:null,name:"Shazia",surname:"Tariq",slug:"shazia-tariq",fullName:"Shazia Tariq"}],corrections:null},{id:"76605",title:"Promoting Resilience in the Face of Fundamental Uncertainty",doi:"10.5772/intechopen.97816",slug:"promoting-resilience-in-the-face-of-fundamental-uncertainty",totalDownloads:328,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Complex systems at different levels (states, organisations, individuals) undergo phase transitions when faced with a sudden shock. The phase transitions are unpredictable and can lead to unstable states and also introduce a source of fundamental uncertainty about the future. In the face of this type of fundamental uncertainty, we know from pioneering work on population health that social determinants (e.g. education, employment, housing, etc.) will have a substantial influence on the ability of individuals and society to be resilient and recover from these shocks. This chapter will start with an overview of complex systems, phase transitions and the nature of fundamental uncertainty. These concepts will then be discussed in light of the COVID-19 pandemic. The importance of social determinants in promoting both mental and physical health, and thus resilience at individual and population levels, will be described and the chapter will finish with an exploration of historical and contemporary examples of means that can be used to support individual and collective resilience in the face of fundamental uncertainty.",signatures:"Anant Jani",downloadPdfUrl:"/chapter/pdf-download/76605",previewPdfUrl:"/chapter/pdf-preview/76605",authors:[{id:"347169",title:"Dr.",name:"Anant",surname:"Jani",slug:"anant-jani",fullName:"Anant Jani"}],corrections:null},{id:"76705",title:"Impact of COVID-19 on Psychological Status of General Population",doi:"10.5772/intechopen.97866",slug:"impact-of-covid-19-on-psychological-status-of-general-population",totalDownloads:440,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"WHO has declared COVID-19 as a pandemic on March 11, 2020. Like the virus affects the entire body, the pandemic affected the entire global trade and economy, leading to the loss of jobs and businesses. Thus, it would be appropriate to quote COVID-19 as a social disease rather than treating only as a medical condition. The COVID-19 pandemic, being a social disease, affects all the individuals of the society in terms of their physical, mental, social health and challenges the economic status of the entire population, irrespective of whether they were physically sick. However, the mental health impact of the COVID-19 pandemic has been overlooked, given its benign nature. We can anticipate a higher prevalence of psychological distress during any pandemic than typical situations. The COVID-19 instils fear and anxiety among people. Isolation and quarantine to reduce disease transmission have a negative impact on one’s mental health. The lockdowns lead to the closure of educational institutions and workplaces, loss of jobs, economic loss, lack of physical activity, restrictions on travel and gatherings. All these factors cumulatively affected the mental stamina of millions worldwide. Given its importance, we have reviewed the impact of COVID-19 on the psychological status of general population.",signatures:"Yuvaraj Krishnamoorthy, Ramya Nagarajan, Gayathri Surendran and Manikandanesan Sakthivel",downloadPdfUrl:"/chapter/pdf-download/76705",previewPdfUrl:"/chapter/pdf-preview/76705",authors:[{id:"287937",title:"Dr.",name:"Yuvaraj",surname:"Krishnamoorthy",slug:"yuvaraj-krishnamoorthy",fullName:"Yuvaraj Krishnamoorthy"},{id:"349144",title:"Dr.",name:"Ramya",surname:"Nagarajan",slug:"ramya-nagarajan",fullName:"Ramya Nagarajan"},{id:"415390",title:"Dr.",name:"Gayathri",surname:"Surendran",slug:"gayathri-surendran",fullName:"Gayathri Surendran"},{id:"415391",title:"Dr.",name:"Manikandanesan",surname:"Sakthivel",slug:"manikandanesan-sakthivel",fullName:"Manikandanesan Sakthivel"}],corrections:null},{id:"76606",title:"Psychoanalysis and Non-Adherence to Medical Advice: An Ethical Dilemma in Covid-19 Pandemic",doi:"10.5772/intechopen.97744",slug:"psychoanalysis-and-non-adherence-to-medical-advice-an-ethical-dilemma-in-covid-19-pandemic",totalDownloads:296,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Mitigation measures required by Covid-19 pandemic have posed severe restrictions on individual freedom and have been met with persistent opposition in minority circles. As non-adherence to preventive measures is believed to increase health risks for the society at large, dissent from official policies has been a source of concern. Within this framework several eminent psychoanalysts have suggested psychoanalysis should be enrolled as a component of health related public opinion campaigns. The chapter will discuss the historical relation between mental health institutions and social control strategies and will formulate a psychoanalytic model of the social dialectic associated with the Coronavirus pandemic. The model will allow the author to offer grounded ethical perspectives on the issue.",signatures:"Paolo Azzone",downloadPdfUrl:"/chapter/pdf-download/76606",previewPdfUrl:"/chapter/pdf-preview/76606",authors:[{id:"324882",title:"Dr.",name:"Paolo",surname:"Azzone",slug:"paolo-azzone",fullName:"Paolo Azzone"}],corrections:null},{id:"76864",title:"Anxiety and Depression in COVID-19 Times",doi:"10.5772/intechopen.98215",slug:"anxiety-and-depression-in-covid-19-times",totalDownloads:354,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"The millennial generation has been known as the most anxious and depressed one, due to lack of more physical attachment. During these COVID-19 times, these problem had been widened for everyone - many had been panic about the illness, the media had played an awful hole on it, creating a scenario of huge risk for lives and jobs. We are facing a perfect storm, where we are not allowed to do most of the recreation and healthie programs - like visit the ones beloved, go to gym, go to a party. The use of internet have a lot of misinformation about the pandemic and even physicians, scientists and health politicians overload us with useless information. It was really hard to identify what was important. In this situation, dealing with uncertainty, anxiety and depression had created a huge problem for physicians and psychologists. How to help and support that. There are many strategies that we have used. First to diminish the search of information over COVID-19, selecting one trustable source. Second, contact your beloved ones, if possible with video call on an everyday basis. Third, develop a routine of physical activities in order to keep your body health. Fourth try to develop a health pattern of food. Together they can diminish the chance of having anxiety and depression. But if you need support for a professional, it’s important to have teams of professional available to give attention to that issues. The very first is a phone support or internet support, by teams that could discuss the problems and develop a personal strategy to deal with this situation. But when that is not enough, we must have a consultation with a physician or a psychologist. The approach must discuss fillings, worries and how to plan this isolation times. Most of us have a hidden agenda and fear that must be addressed and at this time it is important to allow the patients to talk about freely, and to develop empathy with their worries. After that we can promote some activities to diminish the fillings of anxiety and depression.",signatures:"Hamilton Lima Wagner",downloadPdfUrl:"/chapter/pdf-download/76864",previewPdfUrl:"/chapter/pdf-preview/76864",authors:[{id:"281898",title:"M.Sc.",name:"Hamilton Lima",surname:"Wagner",slug:"hamilton-lima-wagner",fullName:"Hamilton Lima Wagner"}],corrections:null},{id:"77064",title:"Adversity, Uncertainty and Elevated Symptoms of Obsessive Compulsive Disorder: A New Understanding through Resiliency and Positive Psychotherapy",doi:"10.5772/intechopen.98304",slug:"adversity-uncertainty-and-elevated-symptoms-of-obsessive-compulsive-disorder-a-new-understanding-thr",totalDownloads:299,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The content of thought, which emerges from the processing of information from the social context lived, is a critical factor that guides whether the behavior is psychopathological or not. In cases where worry, anxiety and fear are dominant in the content of thought, the individual may find himself in some psychopathological processes. Adversity and uncertainty are the main factors that lead to the experience of worry, anxiety and fear which is the last point of these. Uncertainty of information from the social context lived, when matched with adversity, may lead to chaotic situations at the cognitive level, e.g., thought contents such as distortions in thought, severe anxiety and fear. Obsessive compulsive disorder derives from severe worry and anxiety. Although the disorder is classified under anxiety disorders, it is actually a thought distortion disorder. The individual finds himself repeating the strange behavior patterns accompanied by strange thought contents in order to get rid of the severe anxiety and accelerated thought cycle he is exposed to. Ambiguity and uncertainty also may lead to the accelerated thought cycle, ruminations, severe thought distortions, over-generalizations. Ruminations, especially, impair the individual’s ability to think and process emotions gradually. Obsessive Compulsive Disorder will be discussed in terms of ambiguity and uncertainty with the combination of adversity. Positive Psychotherapy, which is one of the latest effective technique in recovery processes of the diseases, will be mentioned.",signatures:"Sevgi Güney",downloadPdfUrl:"/chapter/pdf-download/77064",previewPdfUrl:"/chapter/pdf-preview/77064",authors:[{id:"110081",title:"Ph.D.",name:"Sevgi",surname:"Güney",slug:"sevgi-guney",fullName:"Sevgi Güney"}],corrections:null},{id:"77908",title:"Anxiety, Uncertainty and Resilience during the Pandemic Period-Anthropological and Psychological Perspectives",doi:"10.5772/intechopen.98841",slug:"anxiety-uncertainty-and-resilience-during-the-pandemic-period-anthropological-and-psychological-pers",totalDownloads:350,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"Following any natural disaster, tragedy, calamities, there are upsurge of mental health issues found worldwide. COVID 19 is no exception to them. Public health and infection control domains were the first hit at the peak of pandemic. The news and information were bombarded in traditional print and electronic Medias as well as in social Medias. The tsunami of infodemic was a recent topic of discussion. The responsible reporting, media role, role of Government and Non Government organizations are immense. To combat these challenges and ensuring peace and tranquillity are the biggest task of the policymakers ahead.",signatures:"Ranjan Bhattacharyya",downloadPdfUrl:"/chapter/pdf-download/77908",previewPdfUrl:"/chapter/pdf-preview/77908",authors:[{id:"347365",title:"Associate Prof.",name:"Ranjan",surname:"Bhattacharyya",slug:"ranjan-bhattacharyya",fullName:"Ranjan Bhattacharyya"}],corrections:null},{id:"77524",title:"The Grief Elaboration Process in the Pandemic Scenario: A Group Intervention",doi:"10.5772/intechopen.98837",slug:"the-grief-elaboration-process-in-the-pandemic-scenario-a-group-intervention",totalDownloads:314,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The COVID-19 pandemic has claimed thousands of victims worldwide. To deal with loss is a formidable challenge for all, especially those who experienced losing their loved ones. The grief elaboration process is complex, and the pandemic adds some specific challenges, such as the restrictions to funerals and farewell rituals or the impossibility of saying goodbye due to the sanitary measures. This chapter presents a group psychological intervention aimed at people who lost their relatives to COVID-19. The therapeutic groups were carried out virtually through six sessions and brought together people from all over Brazil. Narrative therapy was the theoretical model adopted. The participants mentioned the moment of diagnosis as decisive for experiencing the disease’s terminality and anguish, promoting guilt and anxiety in the family. In the group, the participants found space to share the painful experience, and throughout the sessions, they were able to develop coping resources. They mentioned strategies, such as activating the family and social support network, recalling legacies and moments they shared with the deceased, and elaborating farewell rituals adapted to the pandemic circumstances. The participants evaluated the group intervention as very important for reframing the pain of loss and restoring future projects since they counted on the help and inspiration of the other participants who went through this painful experience in similar circumstances.",signatures:"Silvia Renata Lordello and Isabela Machado da Silva",downloadPdfUrl:"/chapter/pdf-download/77524",previewPdfUrl:"/chapter/pdf-preview/77524",authors:[{id:"283776",title:"Dr.",name:"Silvia Renata",surname:"Lordello",slug:"silvia-renata-lordello",fullName:"Silvia Renata Lordello"},{id:"349178",title:"Dr.",name:"Isabela",surname:"Machado Da Silva",slug:"isabela-machado-da-silva",fullName:"Isabela Machado Da Silva"}],corrections:null},{id:"77909",title:"Uncertainty in Pandemic Times",doi:"10.5772/intechopen.99454",slug:"uncertainty-in-pandemic-times",totalDownloads:307,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The Covid-19 pandemic has burst upon us as a general test for humanity, for which we were woefully unprepared. We all faced the pandemic with little knowledge and no experience. It is the first pandemic of our lives. Over this period, we have seen a range of conflicting statements, positions and behaviours. On occasion, the scientific community and health professionals have failed to speak with a single voice to convey the urgency of the situation, as their views got lost and scattered in rivulets of opposing theories ranging from denying to ringing the alarm. So many elements were in place for the ‘perfect storm’ to get unleashed … and it did. And as the pandemic wreaked its havoc, many health workers have paid a high price for their selfless dedication and professionalism. We have worked in the absence of clear-cut guidelines, in situations where even the cornerstones of medical ethics have faltered. On the other hand, the fruitful aspects of uncertainty also emerged.",signatures:"Liliana Lorettu, Davide Piu and Saverio Bellizzi",downloadPdfUrl:"/chapter/pdf-download/77909",previewPdfUrl:"/chapter/pdf-preview/77909",authors:[{id:"203859",title:"Prof.",name:"Liliana",surname:"Lorettu",slug:"liliana-lorettu",fullName:"Liliana Lorettu"},{id:"427667",title:"Dr.",name:"Davide",surname:"Piu",slug:"davide-piu",fullName:"Davide Piu"},{id:"427668",title:"Dr.",name:"Saverio",surname:"Bellizzi",slug:"saverio-bellizzi",fullName:"Saverio Bellizzi"}],corrections:null},{id:"77493",title:"Stress and Resilience among Medical Students during Pandemic",doi:"10.5772/intechopen.99001",slug:"stress-and-resilience-among-medical-students-during-pandemic",totalDownloads:266,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Medical students who are future physicians are faced with a lot of uncertainties during this pandemic. It includes both academic as well as clinical difficulties. Previous literature has revealed that the stress among medical students is higher when compared to their peers. The stress has even been more during the pandemic as their role during the pandemic is not clear. The purpose of medical training is to produce good doctors but not at the cost of the integrity of the individuals.’Moral inquiry’ is a term used to represent the ethical dilemma faced by doctors during life-death situations. Helplessness faced by students during emergencies leads to moral inqury which in turn leads to more distress. Most of the Medical universities have responded to the pandemic rapidly, by switching to online mode in teaching. This unpatrolled response also has to lead to more stress among medical students. Resilience, by definition, is the capacity to bounce back productively during a stressful situation. Resilience can be viewed as a personality trait or as a fluid process that nurtures according to the situation and the individuals’ reservoir. In this article, we have tried to emphasise the importance of Resilience.",signatures:"J. Shivananda Manohar, Rajesh Raman and Bindu Annigeri",downloadPdfUrl:"/chapter/pdf-download/77493",previewPdfUrl:"/chapter/pdf-preview/77493",authors:[{id:"317387",title:"Dr.",name:"J. Shivananda",surname:"Manohar",slug:"j.-shivananda-manohar",fullName:"J. Shivananda Manohar"},{id:"347999",title:"Dr.",name:"Rajesh",surname:"Raman",slug:"rajesh-raman",fullName:"Rajesh Raman"},{id:"348000",title:"Dr.",name:"Bindu",surname:"Annigeri",slug:"bindu-annigeri",fullName:"Bindu Annigeri"}],corrections:null},{id:"76383",title:"Loneliness and Psychological Distress: A Mediating Role of Meaning in Life during COVID-19 Pandemic",doi:"10.5772/intechopen.97477",slug:"loneliness-and-psychological-distress-a-mediating-role-of-meaning-in-life-during-covid-19-pandemic",totalDownloads:379,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"The COVID-19 pandemic represents a health crisis with a high amount of loneliness, which in turn may be associated with negative mental health outcome like psychological distress. This chapter aimed to investigate if meaning in life mediated the effect of loneliness on symptoms of psychological distress. A young adult sample (N = 605, 75.7% women) completed the measures of loneliness, psychological distress, and meaning in life. The results indicated that meaning in life mediated the relations between loneliness and psychological distress symptoms. This relation was significant at low, medium, and high levels of meaning in life. The study shows that experience of loneliness is associated with symptoms of psychological distress. Level of meaning in life differentiates the direct and indirect effect of loneliness on psychological distress. Knowledge about the effect of loneliness in response to a health crisis is important for developing treatment and prevention strategies for loneliness, psychological distress, and meaning in life.",signatures:"Murat Yıldırım",downloadPdfUrl:"/chapter/pdf-download/76383",previewPdfUrl:"/chapter/pdf-preview/76383",authors:[{id:"348009",title:"Assistant Prof.",name:"Murat",surname:"Yıldırım",slug:"murat-yildirim",fullName:"Murat Yıldırım"}],corrections:null},{id:"77032",title:"Sleep and Resilience during the COVID-19 Pandemic",doi:"10.5772/intechopen.98298",slug:"sleep-and-resilience-during-the-covid-19-pandemic",totalDownloads:401,totalCrossrefCites:4,totalDimensionsCites:4,hasAltmetrics:0,abstract:"Since early 2020, the COVID-19 pandemic has had a profound effect on the mental health and wellbeing of much of the population. Rates of depression, anxiety, loneliness, suicidal ideation, and other mental health concerns increased during the first year of the pandemic, with heightened fears of the virus, social isolation, and economic instability. Psychological resilience remains a key factor in sustaining healthy emotional functioning during the crisis and facilitating rapid recovery as we move forward to build a better post-pandemic world. Our research, and that of others, suggests that healthy sleep is one of the most powerful aspects of psychological resilience. This chapter will summarize the current literature on psychological resilience, particularly as it relates to the pandemic, and describe the important role of sleep as a key component of resilience capacity. We will discuss novel empirical data linking sleep and resilience during the pandemic. We will conclude with concrete, empirically based suggestions for modulating sleep to sustain psychological resilience during the present crisis and those that may emerge in the future.",signatures:"Sara A. Cloonan, Emily C. Taylor, Michelle R. Persich, Natalie S. Dailey and William D.S. Killgore",downloadPdfUrl:"/chapter/pdf-download/77032",previewPdfUrl:"/chapter/pdf-preview/77032",authors:[{id:"348467",title:"Prof.",name:"William D.S.",surname:"Killgore",slug:"william-d.s.-killgore",fullName:"William D.S. Killgore"},{id:"415470",title:"B.A.",name:"Sara A.",surname:"Cloonan",slug:"sara-a.-cloonan",fullName:"Sara A. Cloonan"},{id:"415472",title:"Ms.",name:"Emily C.",surname:"Taylor",slug:"emily-c.-taylor",fullName:"Emily C. Taylor"},{id:"415473",title:"Dr.",name:"Michelle R.",surname:"Persich",slug:"michelle-r.-persich",fullName:"Michelle R. Persich"},{id:"415474",title:"Dr.",name:"Natalie S.",surname:"Dailey",slug:"natalie-s.-dailey",fullName:"Natalie S. Dailey"}],corrections:null},{id:"77114",title:"Potential Effects of the COVID-19 Pandemic on Children and Adolescents with Separation Anxiety Disorder",doi:"10.5772/intechopen.98334",slug:"potential-effects-of-the-covid-19-pandemic-on-children-and-adolescents-with-separation-anxiety-disor",totalDownloads:422,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Children with separation anxiety disorder (SAD) experience unrealistic fear of being separated from their significant caregivers (mostly parents). The occurrence of pathological separation anxiety is determined by many factors: parental attitudes, their mental and physical health, but also the way of perceiving the environment, traumatic events in the child’s family and life, as well as genetic and individual effects. Pandemic situation and related isolation caused change in the current lifestyle. Both psychological (i.e. the novelty of the social situation, negative information in the mass media, fear of their own live and their loved ones) and daily-life routine disturbances (i.e. the closure of schools and restrictions of contacts with peers, limited contacts with distant family members, remote work of parents) generate difficulties for children and can contribute anxiety among children with SAD. Paradoxically, despite the fact that children and adolescents are at home, the COVID-19 pandemic may intensify SAD, exacerbating factors underlying separation anxiety. It turns out that family social isolation can escalate conflicts. This, in turn, adversely affects relationships between family members and can reduce children’s sense of security. Due to pandemic problematic access to specialized health care, especially personal contact with a psychotherapist, children with SAD suffer from insufficient professional help.",signatures:"Malgorzata Dabkowska and Agnieszka Dabkowska-Mika",downloadPdfUrl:"/chapter/pdf-download/77114",previewPdfUrl:"/chapter/pdf-preview/77114",authors:[{id:"48667",title:"Dr.",name:"Malgorzata",surname:"Dabkowska",slug:"malgorzata-dabkowska",fullName:"Malgorzata Dabkowska"},{id:"58055",title:"Dr.",name:"Agnieszka",surname:"Dabkowska-Mika",slug:"agnieszka-dabkowska-mika",fullName:"Agnieszka Dabkowska-Mika"}],corrections:null},{id:"77215",title:"Child and Adolescent Anxiety as a Result of the COVID-19 Pandemic",doi:"10.5772/intechopen.98503",slug:"child-and-adolescent-anxiety-as-a-result-of-the-covid-19-pandemic",totalDownloads:327,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"As the coronavirus disease 2019 (COVID-19) pandemic has spread, so has the psychological impact of the disease been felt worldwide. Among the various types of psychological problems that are caused by COVID-19, anxiety poses a great threat to the physical and mental health of children and adolescents. With an aim of advancing the current work of diagnosing and treating child and adolescent anxiety as a result of the COVID-19 pandemic, this chapter discusses this noticeable global health issue focusing on the following key parts: possible etiology, clinical characteristics, diagnosis and available therapeutic options.",signatures:"Jie Luo and Alfred Shaw",downloadPdfUrl:"/chapter/pdf-download/77215",previewPdfUrl:"/chapter/pdf-preview/77215",authors:[{id:"348850",title:"Dr.",name:"Jie",surname:"Luo",slug:"jie-luo",fullName:"Jie Luo"},{id:"349138",title:"Dr.",name:"Alfred",surname:"Shaw",slug:"alfred-shaw",fullName:"Alfred Shaw"}],corrections:null},{id:"76735",title:"Anxiety, Coping Strategies and Resilience among Children and Adolescents during COVID-19 Pandemic: A Systematic Review",doi:"10.5772/intechopen.97828",slug:"anxiety-coping-strategies-and-resilience-among-children-and-adolescents-during-covid-19-pandemic-a-s",totalDownloads:479,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"COVID-19 pandemic is a global challenge that affects people’s mental health worldwide. Experiencing anxiety by children and adolescents, who are vulnerable to the impact of sustained stressors during developmentally sensitive periods, can lead to long-lasting effects on their health. The article brings insight into the short and long-term consequences of the COVID-19 pandemic on the children and adolescents’ mental health. The particular aim of this study is to investigate the relationship between anxiety, stress, and resilience in young individuals in the context of COVID-19. A review of the psychological effects of pandemic on children and adolescents was done using electronic databases. Most reviewed studies reported risk factors of psychosocial problems among children and adolescents during pandemics, resilience and positive coping as protective factors for the occurrence of anxiety and stress symptoms, and mediating role of parents’ stress impact on children’s behavioral and emotional problems. Clinical implications are discussed and additional research is suggested.",signatures:"Malgorzata Dąbkowska, Anna Kobierecka-Dziamska and Monika Prusaczyk",downloadPdfUrl:"/chapter/pdf-download/76735",previewPdfUrl:"/chapter/pdf-preview/76735",authors:[{id:"48667",title:"Dr.",name:"Malgorzata",surname:"Dabkowska",slug:"malgorzata-dabkowska",fullName:"Malgorzata Dabkowska"},{id:"349165",title:"Dr.",name:"Anna",surname:"Kobierecka-Dziamska",slug:"anna-kobierecka-dziamska",fullName:"Anna Kobierecka-Dziamska"},{id:"349166",title:"Ms.",name:"Monika",surname:"Prusaczyk",slug:"monika-prusaczyk",fullName:"Monika Prusaczyk"}],corrections:null},{id:"78271",title:"Is the Pandemic a Risk Factor for Eating Disorders?",doi:"10.5772/intechopen.99792",slug:"is-the-pandemic-a-risk-factor-for-eating-disorders-",totalDownloads:223,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"COVID-19 has already established direct or indirect effect on the lives of everyone. One of its many consequences is exacerbation of eating disorders’ (ED) triggers. Numerous risk factors for ED are enhanced during pandemic – anxiety, fear, depressed mood. Distance learning or working may result in loss of daily-life routine and feeling of being overwhelmed with duties. Due to forced isolation people are more exposed to social media pressure. Additionally, awareness of limitations of physical activity can develop fear of gaining the weight. These are typical symptoms of Anorexia Nervosa, a disease with the highest mortality rate among psychiatric disorders. Frustration, tedium and lack of external distractors can lead to inappropriate food-related coping style. Especially during the first wave of the pandemic, society was cautious about fresh food supplies and therefore many decided to stock up with processed, unhealthy food. Aggregation of stressors (e.g., worries about health, financial problems, loneliness) may promote binge eating.",signatures:"Agnieszka Dąbkowska-Mika",downloadPdfUrl:"/chapter/pdf-download/78271",previewPdfUrl:"/chapter/pdf-preview/78271",authors:[{id:"58055",title:"Dr.",name:"Agnieszka",surname:"Dabkowska-Mika",slug:"agnieszka-dabkowska-mika",fullName:"Agnieszka Dabkowska-Mika"}],corrections:null},{id:"78150",title:"A Year after - Could We Move beyond Psychosomatics and Dissociation",doi:"10.5772/intechopen.99227",slug:"a-year-after-could-we-move-beyond-psychosomatics-and-dissociation",totalDownloads:220,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Living in a global world that is continuously changing while creating the experience of fluidity, we are losing ground and, therefore, stability. It affects mental health across the life span. During the last 12 months from the first WHO notification of the novel coronavirus 2019-nCoV, humanity started to experience a dramatic change in the level of plans, norms, expectations. Besides fear for personal safety and health, the directed distancing increased the gap in everyday quality of possibilities for personal contacts and support. Losing the ground and experience trembling, we were inevitably facing blurred boundaries, insecurity and a direct attack on our will and who we are. Furthermore, a year after, we realize that we are in the fertile ground for the manifestation and experience of anxiety, panic, and numerous psychosomatic disorders. The whole of humanity is suffering. Hence, those coming from helping professions (psychologist, psychotherapists, social workers) dealing with mental health are experiencing the kick even harder. The research we are conducting is checking their wellbeing a year after.",signatures:"Emilija Stoimenova Canevska, Ena Canevska and Jana Petreska",downloadPdfUrl:"/chapter/pdf-download/78150",previewPdfUrl:"/chapter/pdf-preview/78150",authors:[{id:"325539",title:"Prof.",name:"Emilija",surname:"Stoimenova Canevska",slug:"emilija-stoimenova-canevska",fullName:"Emilija Stoimenova Canevska"},{id:"426657",title:"Dr.",name:"Ena",surname:"Canevska",slug:"ena-canevska",fullName:"Ena Canevska"},{id:"426658",title:"Dr.",name:"Jana",surname:"Petreska",slug:"jana-petreska",fullName:"Jana Petreska"}],corrections:null},{id:"76816",title:"Uncertainty, Sex and Sexuality during the Pandemic: Impact on Psychosocial Resilience",doi:"10.5772/intechopen.98231",slug:"uncertainty-sex-and-sexuality-during-the-pandemic-impact-on-psychosocial-resilience",totalDownloads:385,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:1,abstract:"The Coronavirus disease 2019 (COVID-19) pandemic has been a global unprecedented health threat. Besides the myriad of effects on public health, the psychosocial implications of the outbreak have been far-fetched. Though the increased prevalence of psychiatric disorders, reduced access to care and social vulnerabilities have been highlighted in literature, the immense impact on sexuality and psychosexual health tends to be silent. The World Health Organization (WHO) defines sexual health as “a state of physical, emotional, mental and social well-being in relation to sexuality; it is not merely the absence of disease, dysfunction or infirmity.” Sexual practices and intimacy have been influenced by more ways than one, namely fear of infection, ambiguity about viral spread, misinformation, physical distancing, travel restrictions, intimate partner violence and deprivation of ‘social touch’. The frontline workers, socio-economically impoverished groups, age and sexual minorities are especially affected. Sexual and reproductive rights are compromised due to reduced help-seeking, panic and stigma related to the outbreak. Psychological resilience helps one navigate through stressful situations and assumes a special importance during the ongoing crisis. This chapter reviews the multi-faceted intersections between sexual health and resilience, highlights the possible roles of pandemic-related uncertainty and advocates for certain guidelines to promote and preserve healthy expressions of sexuality for coping during COVID-19.",signatures:"Debanjan Banerjee, Sanchari Mukhopadhyay, Abhinav Tandon and T.S. Sathyanarayana Rao",downloadPdfUrl:"/chapter/pdf-download/76816",previewPdfUrl:"/chapter/pdf-preview/76816",authors:[{id:"317231",title:"Prof.",name:"T S Sathyanarayana",surname:"Rao",slug:"t-s-sathyanarayana-rao",fullName:"T S Sathyanarayana Rao"},{id:"317388",title:"Dr.",name:"Abhinav",surname:"Tandon",slug:"abhinav-tandon",fullName:"Abhinav Tandon"},{id:"350093",title:"Dr.",name:"Debanjan",surname:"Banerjee",slug:"debanjan-banerjee",fullName:"Debanjan Banerjee"},{id:"416659",title:"Dr.",name:"Sanchari",surname:"Mukhopadhyay",slug:"sanchari-mukhopadhyay",fullName:"Sanchari Mukhopadhyay"}],corrections:null},{id:"77039",title:"COVID-19 Pandemic; Anxiety and Depression among Frontline Healthcare Workers: Rising from the Ashes",doi:"10.5772/intechopen.98274",slug:"covid-19-pandemic-anxiety-and-depression-among-frontline-healthcare-workers-rising-from-the-ashes",totalDownloads:367,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"This chapter gives an insight into the psychological journey of the essential healthcare workers (HCWs) during the COVID-19 pandemic. The catastrophe which started off with uncertainty, provoked fear-related behaviors among the frontline doctors, nurses and paramedical staff. With meager resources and lack of a disaster plan, fire-fighting was a reflex response of healthcare institutions. Though the whole world seemed to be unprepared for the calamity, developing countries with fragile healthcare systems were more vulnerable to collapse. The negative aura was complicated by mistrust among the general population, regarding healthcare workers, institutions and government. Furthermore, with economic downfall; balancing work and protecting the family was a challenge for HCWs, especially during the pandemic peak. The psychological distress translated to rising incidence of depression and anxiety among them. As institutions gained insight into psychosocial issues of HCWs; support and therapies were offered to them. Positive messages labelling HCWs as “Heroes of the Pandemic” were circulated and structured programs developed to address their needs. With the advent of COVID-19 vaccine, a ray of hope emerged, although there are still apprehensions about its efficacy and side-effects. The whole world now eagerly awaits the calamity to perish while normality can rise from ashes.",signatures:"Salman Sharif and Faridah Amin",downloadPdfUrl:"/chapter/pdf-download/77039",previewPdfUrl:"/chapter/pdf-preview/77039",authors:[{id:"350303",title:"Prof.",name:"Faridah",surname:"Amin",slug:"faridah-amin",fullName:"Faridah Amin"},{id:"350305",title:"Prof.",name:"Salman",surname:"Sharif",slug:"salman-sharif",fullName:"Salman Sharif"}],corrections:null},{id:"77579",title:"Anxiety of Dental Professionals during Covid-19 Pandemic",doi:"10.5772/intechopen.98994",slug:"anxiety-of-dental-professionals-during-covid-19-pandemic",totalDownloads:282,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Coronavirus (COVID-19) is an enveloped RNA virus with a size of ~350 kilobase-pair and COVID-19 is commonly transmitted via aerosols, saliva, nasal droplets, and surface contact which causes severe acute respiratory tract infection among infected humans, and recently many cases declared with severe blood clotting. The average incubation period ranges from 4 to 14 days. The infected person usually presents fever accompanying an upper respiratory tract infection (RTI) and complaints of dry cough, and dyspnea. It is highly recommended to keep any suspected individuals in quarantine (isolation). After its first emergence in Wuhan, China in 2019 and then intercontinental spread it was declared as a pandemic by the World Health Organization in March 2020. The pandemic of COVID-19 deeply affected the whole world and healthcare workers as front liners are most at risk among professional groups. Dentistry is among the riskiest occupational groups that include all direct and indirect ways of COVID-19 spread. In this process, the dentists who experienced the effects of COVID-19 in the working conditions, economy, and social fields were psychologically negatively affected, and their anxiety, fear, and stress levels increased. In this review, we discuss the increased risk of the spread of coronavirus during dental operative procedures and the effects of the COVID-19 pandemic on the anxiety level, depression, and mental health of dental professionals.",signatures:"Pinar Kiymet Karataban",downloadPdfUrl:"/chapter/pdf-download/77579",previewPdfUrl:"/chapter/pdf-preview/77579",authors:[{id:"272237",title:"Dr.",name:"Pinar",surname:"Karataban",slug:"pinar-karataban",fullName:"Pinar Karataban"}],corrections:null},{id:"76779",title:"Children Living a Global Pandemic: Anxiety Repercussions",doi:"10.5772/intechopen.98212",slug:"children-living-a-global-pandemic-anxiety-repercussions",totalDownloads:293,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"A global pandemic caused by SARS-CoV-2 is still beaten our world. The disease, termed COVID-19 by the WHO, has a wide range of clinical manifestations, ranging from a mild, self-limiting form of the disease to multiple organ failure and death, forcing governments to take measures to mitigate the transmission and reduce the economic impact. However, the paediatric manifestation appears to take a milder form of the disease but they are not oblivious to the consequences of the disease. They suffered personal and parental lost, broke their social relationships, forced to home confinement, school closures, all of them with secondary implications. As a result, children’s anxiety levels and manifestations have increased during pandemic. To prevent and counteract this situation, measures were implemented like increase physical activity, a balanced diet, and regular sleep pattern; and in relationship sphere use social media to stay in touch with school mates and relatives.",signatures:"Salvador I. Garcia-Adasme and Alejandro López-Escobar",downloadPdfUrl:"/chapter/pdf-download/76779",previewPdfUrl:"/chapter/pdf-preview/76779",authors:[{id:"350502",title:"Dr.",name:"Alejandro",surname:"López-Escobar",slug:"alejandro-lopez-escobar",fullName:"Alejandro López-Escobar"},{id:"350521",title:"Ph.D. Student",name:"Salvador",surname:"García-Adasme",slug:"salvador-garcia-adasme",fullName:"Salvador García-Adasme"}],corrections:null},{id:"76713",title:"The Psychological Aspects of Home-Makers and Women during Pandemic",doi:"10.5772/intechopen.97687",slug:"the-psychological-aspects-of-home-makers-and-women-during-pandemic",totalDownloads:423,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"Depression and anxiety are two faces of a coin and we unfortunately fail to understand the plight of a person suffering from any one of these mental conditions. However, nowadays people have started considering mental health as a serious and complex issue, but still, those suffering from it tend to shy away and hide in arrears their own dark curtains. Sometimes, a very normal looking person may also be a victim of mental breakdown and anxiety. He may be working out fine, laughing, smiling, talking and all, but somewhere deep inside and within, he may be crying his heart out. It just does not visibly appear so on the outside. Moreover, in the phase of COVID, this situation has aggravated a lot because of various reasons like loss of jobs, work from home, salary reductions and cost cuttings etc. The effect of these problems fell on the families overall, but the most suffered category was – THE HOMEMAKERS, or in other words, THE HOUSEWIVES. Housewives have usually higher resilience when it comes to handling problems and family issues as they have an inbuilt capacity and trait to handle and adjust themselves in any atmosphere and ambience after marriage, but this COVID period was equally tough to handle for them as well. Specifically, if we talk about housewives, the entire COVID period was difficult for them to handle because of multiple reasons which will be mentioned point by point.",signatures:"Samina Firoz Wagla Wala",downloadPdfUrl:"/chapter/pdf-download/76713",previewPdfUrl:"/chapter/pdf-preview/76713",authors:[{id:"351133",title:"Ms.",name:"Samina",surname:"Wagla Wala",slug:"samina-wagla-wala",fullName:"Samina Wagla Wala"}],corrections:null},{id:"77680",title:"Anxiety, Uncertainty, and Resilience of Medical Students Worldwide during the COVID-19 Pandemic",doi:"10.5772/intechopen.99226",slug:"anxiety-uncertainty-and-resilience-of-medical-students-worldwide-during-the-covid-19-pandemic",totalDownloads:296,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"The COVID-19 pandemic significantly impacted medical education worldwide. While healthcare professionals labored to ensure proper care for COVID-19 patients, medical students suffered from high rates of anxiety, uncertainty, burnout, and depressive symptoms. Whilst students in the pre-clinical phase of education faced disruption of didactic lectures and laboratory training, senior medical students faced uncertainty regarding their clinical rotations and internships, which are vital for practical exposure to healthcare. Several studies across the world demonstrated that clinical learning was significantly affected, with students in many countries completely cut off from in-person rotations. The disruption of the clinical curriculum coupled with a sense of failure to contribute at a time of significant need often led to despair. Reforms proposed and/or implemented by governments, medical advisory boards, medical schools, and other administrative bodies were felt to be insufficient by the medical student fraternity at large. Consequently, these students continue to face high rates of anxiety, depression, and a general sense of cynicism. In this student-authored perspective, we highlight the challenges faced by and the psychological impact on medical students directly or indirectly from the pandemic.",signatures:"Mohammad Abdullah Sarkar and Ahmad Ozair",downloadPdfUrl:"/chapter/pdf-download/77680",previewPdfUrl:"/chapter/pdf-preview/77680",authors:[{id:"349724",title:"Dr.",name:"Ahmad",surname:"Ozair",slug:"ahmad-ozair",fullName:"Ahmad Ozair"},{id:"353300",title:"Mr.",name:"Mohammad Abdullah",surname:"Sarkar",slug:"mohammad-abdullah-sarkar",fullName:"Mohammad Abdullah Sarkar"}],corrections:null},{id:"77734",title:"Cyberchondria and Its Effects on Anxiety during Covid-19 Pandemic",doi:"10.5772/intechopen.98507",slug:"cyberchondria-and-its-effects-on-anxiety-during-covid-19-pandemic",totalDownloads:264,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Cyberchondria is a blend of the words cyber and hypochondriac. Social isolation with easily available information on the Internet for little or no cost created a havoc. It is an abnormal behavioral pattern in the emotional state. There were hundreds of social media groups created during the pandemic. Many people including the healthcare workers started sharing their experiences, positive and negative. It created a lot of anxiety and depression among the general population. As we already know people with anxiety and depression react and respond more to information available online without verifying the facts. Though the social media groups helped the readers with innumerable information but it had its flaws. Patients with cyberchondria increased and also the burden on healthcare systems.",signatures:"Suman Shekar and Avinash Aravantagi",downloadPdfUrl:"/chapter/pdf-download/77734",previewPdfUrl:"/chapter/pdf-preview/77734",authors:[{id:"414671",title:"M.D.",name:"Suman",surname:"Shekar",slug:"suman-shekar",fullName:"Suman Shekar"},{id:"417617",title:"Dr.",name:"Avinash",surname:"Aravantagi",slug:"avinash-aravantagi",fullName:"Avinash Aravantagi"}],corrections:null},{id:"77428",title:"Indigenous Peoples, Uncertainty and Exclusion in the Global South in Periods of the Pandemic",doi:"10.5772/intechopen.98785",slug:"indigenous-peoples-uncertainty-and-exclusion-in-the-global-south-in-periods-of-the-pandemic",totalDownloads:276,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The indigenous peoples are distributed in all regions of the world, representing more than 6% of the world’s population. According to UN data, the pandemic has disproportionately affected indigenous groups, aggravating the structural inequalities and processes of widespread historical discrimination and exclusion present in the Global South, for example, high rates of extreme poverty, social exclusion, high prevalence of the disease, and limited and in some cases non-existent access to health care. Also, indigenous peoples have a great wealth of knowledge, traditional practices, cultural forms, and access to natural resources, as well as forms of collective social organization and community life that result in resilience factors in response to adversity and uncertainty. In this way, the chapter focuses from a descriptive-analytical approach on the situation of indigenous peoples and the pandemic, analyzing the forms of responses, their resilient action in the face of uncertainties and structural exclusions in the Global South.",signatures:"Javier Lastra-Bravo",downloadPdfUrl:"/chapter/pdf-download/77428",previewPdfUrl:"/chapter/pdf-preview/77428",authors:[{id:"305413",title:"Ph.D. Student",name:"Javier",surname:"Lastra-Bravo",slug:"javier-lastra-bravo",fullName:"Javier Lastra-Bravo"}],corrections:null},{id:"75957",title:"Loss of Employment and Reduction of Income during the COVID-19 Pandemic in the Maranhão State, Brazil",doi:"10.5772/intechopen.97095",slug:"loss-of-employment-and-reduction-of-income-during-the-covid-19-pandemic-in-the-maranh-o-state-brazil",totalDownloads:300,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"To estimate the prevalence and factors associated to the loss of employment and reduction of income during the covid-19 pandemic in the state of Maranhão, Brazil. A population-based household survey was performed, from October 19 to 30, 2020. The estimates considered clustering, stratification and non-response. The sample selection was carried out in three stages (stratum, census tracts and households). After systematic analysis, thirty sectors were selected in each stratum, totaling 150 sectors, with the number of households in each sector set at 34 households, totaling 5,100 households and one inhabitant per household (resident for at least six months and with 1-year-old or more) selected by simple random sample. To this research were analyzed 3,297 inhabitants among 18 and 64 years old. The Loss of employment and income from the pandemic was questioned. Descriptive analysis (weighted frequency) and Pearson’s chi-square test were performed to verify univariate association between independent variables and the outcome (p < 0.05). The prevalence of loss of employment and income was 12.1% (95%CI 10.5–13.7%), but another 39.7% (95% CI 37.3–42.1%) were already out of the market before the pandemic. This loss was statistically greater among residents of the largest and wealthiest cities in the state (stratum with the state capital: 22.7%; 95% CI 18.8–27.2; and in cities with more than 100 thousand inhabitants: 12.4%; 95% CI 9.9–15.6), male (14.3%; 95% CI 11.9–17.3; p = 0.037), middle-aged adults between 30 and 49 years (15.3%; 95% CI 12.8–18.2; p = 0.001), medium level (15.3%; 95% CI 12.9–18.1; p = 0.003) and higher education (14.4%; 95% CI 9.4–21.5; p = 0.003) and users of public transportation (14.6%; 95% CI 12.4–17.2; p = 0.005), and among those who received this aid was much higher (50.4%; 95% CI 33.2–67.4; p = 0.001). The results showed a relevant prevalence of loss of work and income in Maranhão and its association with individual and contextual factors. They revealed the groups and contexts most affected socioeconomically by the pandemic and that should deserve special attention from public income transfer strategies.",signatures:"Bruno Luciano Carneiro Alves de Oliveira",downloadPdfUrl:"/chapter/pdf-download/75957",previewPdfUrl:"/chapter/pdf-preview/75957",authors:[{id:"311063",title:"Dr.",name:"Bruno",surname:"Luciano Carneiro Alves de Oliveira",slug:"bruno-luciano-carneiro-alves-de-oliveira",fullName:"Bruno Luciano Carneiro Alves de Oliveira"}],corrections:null},{id:"76315",title:"The Impact of Covid-19 Pandemic on Community Psychiatric Services in Northern Italy",doi:"10.5772/intechopen.97156",slug:"the-impact-of-covid-19-pandemic-on-community-psychiatric-services-in-northern-italy",totalDownloads:334,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The Covid-19 pandemic, started brutally in February 2020 in Northern Italy (first European area hit by virus), has induced the most drastic and prolonged containment measures by a European government. The most affected areas of the Italian territory were Lombardy and Veneto. A severe and global lock-down was ordered for more than two months, with the closure of essential medical services among others. All health resources have been diverted to address the health crisis caused by the pandemic. During the lock-down, however, the only community medicine services that remained open were mental health services: psychiatry, the area of addictions, child neuropsychiatry. The community facilities have always provided services favoring, on the one hand, the maintenance of care and rehabilitation paths for patients in care, and on the other, allowing anyone who needs to have access to treatment. The operators were also involved at the forefront in the management of covid + patients and in the support paths for the management of the operators’ stress. In this chapter, we want to describe the working conditions and the organizational responses of our services, referring to a large catchment area of the region most affected by covid-19.",signatures:"Federico Durbano, Barbara Marchesi, Silvia Carnevali, Luisa Elisabetta Sonzogno and Claudio Arici",downloadPdfUrl:"/chapter/pdf-download/76315",previewPdfUrl:"/chapter/pdf-preview/76315",authors:[{id:"157077",title:"Dr.",name:"Federico",surname:"Durbano",slug:"federico-durbano",fullName:"Federico Durbano"},{id:"346618",title:"Dr.",name:"Barbara",surname:"Marchesi",slug:"barbara-marchesi",fullName:"Barbara Marchesi"},{id:"346619",title:"Dr.",name:"Silvia",surname:"Carnevali",slug:"silvia-carnevali",fullName:"Silvia Carnevali"},{id:"346620",title:"Dr.",name:"Luisa Elisabetta",surname:"Sonzogno",slug:"luisa-elisabetta-sonzogno",fullName:"Luisa Elisabetta Sonzogno"},{id:"352449",title:"Dr.",name:"Claudio",surname:"Arici",slug:"claudio-arici",fullName:"Claudio Arici"}],corrections:null},{id:"77378",title:"Vulnerable Groups and COVID-19 Pandemic; How Appropriate Are Psychosocial Responses?",doi:"10.5772/intechopen.98762",slug:"vulnerable-groups-and-covid-19-pandemic-how-appropriate-are-psychosocial-responses-",totalDownloads:259,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Covid-19 pandemic has had adverse health, economic and social consequences on different communities, groups and individuals. Vulnerable groups are more likely to contract the infection and suffer from mental disorders particularly anxiety due to lack of access to health and social resources, lower income and less awareness etc. In this chapter, in addition to a description of the psychological and social conditions of vulnerable groups including women, children, the elderly, and minority groups during the pandemic, the factors influencing the success of psychosocial interventions provided for these groups and the weak points and upcoming challenges will be addressed. Finally, the conclusion will offer some recommendation for coping with the future circumstances.",signatures:"Amir Moghanibashi-Mansourieh",downloadPdfUrl:"/chapter/pdf-download/77378",previewPdfUrl:"/chapter/pdf-preview/77378",authors:[{id:"346672",title:null,name:"Amir",surname:"Moghanibashi-Mansourieh",slug:"amir-moghanibashi-mansourieh",fullName:"Amir Moghanibashi-Mansourieh"}],corrections:null},{id:"75513",title:"COVID-19 Pandemic and Initial Psychological Responses by Bangladeshi People",doi:"10.5772/intechopen.96624",slug:"covid-19-pandemic-and-initial-psychological-responses-by-bangladeshi-people",totalDownloads:417,totalCrossrefCites:0,totalDimensionsCites:2,hasAltmetrics:0,abstract:"The present study was aimed to investigate the causes of COVID-19 worry and its effect on initial behaviors that observed in early stage of the COVID-19 outbreak in Bangladesh. In the online survey, participants’ were asked about normative concerns, COVID-19 worry, initial behaviors, and the neuroticism personality trait. Results of the study demonstrated that (i) higher normative concerns and neurotic trait were predictors of higher COVID-19 worry; and (ii) higher normative concerns and COVID-19 worry significant predictors of buying preparatory materials, higher worry for postponing travel plan, and higher worry and neuroticism for purchasing daily commodities more than usual and difficulties in concentration.",signatures:"Oli Ahmed, Md Zahir Ahmed, Zhou Aibao, Sohan Mia and Md Arif Uddin Khan",downloadPdfUrl:"/chapter/pdf-download/75513",previewPdfUrl:"/chapter/pdf-preview/75513",authors:[{id:"346925",title:"Mr.",name:"Md Zahir",surname:"Ahmed",slug:"md-zahir-ahmed",fullName:"Md Zahir Ahmed"},{id:"347584",title:"Mr.",name:"Oli",surname:"Ahmed",slug:"oli-ahmed",fullName:"Oli Ahmed"},{id:"347585",title:"Mr.",name:"Sohan",surname:"Mia",slug:"sohan-mia",fullName:"Sohan Mia"},{id:"347586",title:"Mr.",name:"Md Arif Uddin",surname:"Khan",slug:"md-arif-uddin-khan",fullName:"Md Arif Uddin Khan"},{id:"347588",title:"Dr.",name:"Zhou",surname:"Aibao",slug:"zhou-aibao",fullName:"Zhou Aibao"}],corrections:null},{id:"78171",title:"Living with Uncertainty in Times of Pandemic: The View of Working Students in Higher Education",doi:"10.5772/intechopen.99793",slug:"living-with-uncertainty-in-times-of-pandemic-the-view-of-working-students-in-higher-education",totalDownloads:429,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Today we live in times of real uncertainty. All of us, young, old, adults or children, experience new ways of facing daily challenges. The education and health sectors are naturally the most affected and deserve to be assessed for the impacts of this pandemic. This chapter aims to focus its analysis on a specific group of students in higher education: working students. In fact, this population group has a distinct profile from “regular” students in higher education. Typically, the student role is not the predominant one in their lives, competing with their roles as active workers and as heads of their families. Choosing a quantitative scientific methodology, about a hundred working student were the target of a survey exploring not only their greatest anxieties and fears, but also the ways they choose to deal with it, namely their exposure to media coverage of the COVID-19. It is expected that the results will contribute to a critical reflection on the challenges that this pandemic poses to us, identifying clues to better manage and overcome them.",signatures:"Diana Dias",downloadPdfUrl:"/chapter/pdf-download/78171",previewPdfUrl:"/chapter/pdf-preview/78171",authors:[{id:"347123",title:"Prof.",name:"Diana",surname:"Dias",slug:"diana-dias",fullName:"Diana Dias"}],corrections:null},{id:"77464",title:"COVID 19 and Quality of Life in Indian Context",doi:"10.5772/intechopen.98477",slug:"covid-19-and-quality-of-life-in-indian-context",totalDownloads:270,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Battling the novel COVID-19 pandemic has caused emotional distress and many nations lost their humans at the fight against the virus. Quality of Life (QOL) has a wide range of contexts, including the fields of international development, healthcare, politics and employment. Standard indicators of the quality of life include wealth, employment, the environment, physical and mental health, education, recreation and leisure time, social belonging, religious beliefs, safety, security and freedom. Being a poor economic country like India, lockdown during COVID 19 devastated occupation, education, recreation and money from the people and the fear of the disease impacts not only on the health of the individuals but also the quality of life of individual is affected.",signatures:"Ganapathy Sankar Umaiorubagam, Monisha Ravikumar and Santhana Rajam Sankara Eswaran",downloadPdfUrl:"/chapter/pdf-download/77464",previewPdfUrl:"/chapter/pdf-preview/77464",authors:[{id:"347731",title:"Ms.",name:"Monisha",surname:"Ravikumar",slug:"monisha-ravikumar",fullName:"Monisha Ravikumar"},{id:"348550",title:"Prof.",name:"Ganapathy Sankar",surname:"Umaiorubagam",slug:"ganapathy-sankar-umaiorubagam",fullName:"Ganapathy Sankar Umaiorubagam"},{id:"419910",title:"Mrs.",name:"Santhana",surname:"Rajam Sankara Eswaran",slug:"santhana-rajam-sankara-eswaran",fullName:"Santhana Rajam Sankara Eswaran"}],corrections:null},{id:"77445",title:"COVID 19 and Myriad of Psychological Problems in Indian Context",doi:"10.5772/intechopen.98768",slug:"covid-19-and-myriad-of-psychological-problems-in-indian-context",totalDownloads:282,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Corona Virus 2019 (COVID 19) is impacting every family financially as well as emotionally. There is a panic situation existed throughout the world. Due to the presence of Novel Corona Virus, there are innumerous defects and changes existed in everybody’s routine activities of daily living and other recreational tasks. As the pandemic outbreak in India was on-going, the Government of India took stringent measures to limit the cases by far in that stage only, by initiating a major lockdown pan-India and also by shifting the immigrants to the special quarantine facilities prepared by the Indian Military directly from the airports and seaports for a minimum of 14 days. The lives of people were drastically affected with lock-down and fear related to the disease’s potential effects and transmission. The fear due to the contraction of COVID -19 is on the rise because of the death tolls and global spread. For low income country like India, financial crisis had troubled the lives of everybody. For older adults, there is a fear of death as well as fear of saving the lives of their loved one. Adapting to this new normal life is a real challenge for older adults in middle and low economic zone like India. Indian people are going through a myriad of psychological problems in adjusting to the current lifestyles and fear of the disease.",signatures:"Ganapathy Sankar Umaiorubagam, Monisha Ravikumar and Santhana Rajam Sankara Eswaran",downloadPdfUrl:"/chapter/pdf-download/77445",previewPdfUrl:"/chapter/pdf-preview/77445",authors:[{id:"347731",title:"Ms.",name:"Monisha",surname:"Ravikumar",slug:"monisha-ravikumar",fullName:"Monisha Ravikumar"},{id:"348550",title:"Prof.",name:"Ganapathy Sankar",surname:"Umaiorubagam",slug:"ganapathy-sankar-umaiorubagam",fullName:"Ganapathy Sankar Umaiorubagam"}],corrections:null},{id:"77772",title:"Pleasant Activities among Young Adults and Their Lack during the COVID-19 Pandemic",doi:"10.5772/intechopen.98997",slug:"pleasant-activities-among-young-adults-and-their-lack-during-the-covid-19-pandemic",totalDownloads:255,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The pandemic COVID-19 burst in the Slovak Republic in March of the 2020 year. Subsequently, the schools were closed on the 10th of March and the everyday life in the country was for a long uncertain time questionable. The curfew slowed down the outdoor activities and has brought sudden changes also in the lives of young active people. This can be a time of uncertainty, and the stress. To do some pleasant activities can act as a stress reliever, but in the pandemic time not all pleasant activities can be realized. We were interested in lack of doing pleasant activities during the pandemic COVID-19 time. We analyzed 195 different activities in life of young mostly sporting people, whether a given activity is popular and pleasant for individuals, the occurrence and frequency of activity implementation before pandemic, during pandemic and feelings the lack of this activity during pandemic. We found out the most pleasant activity for men – non-organized, spontaneous sporting activity and for women – laughing. We recorded statistically significant decline t(14.856) = 48, p < .001 in frequency of doing pleasant activities in comparison before and during COVID-19. The most missing activity was inviting friends’ visits.",signatures:"Janka Peráčková and Pavol Peráček",downloadPdfUrl:"/chapter/pdf-download/77772",previewPdfUrl:"/chapter/pdf-preview/77772",authors:[{id:"348732",title:"Associate Prof.",name:"Janka",surname:"Peráčková",slug:"janka-perackova",fullName:"Janka Peráčková"},{id:"348733",title:"Prof.",name:"Pavol",surname:"Peráček",slug:"pavol-peracek",fullName:"Pavol Peráček"}],corrections:null},{id:"76851",title:"Forecasting the Long-Term Effects of the Pandemic on Children: Towards a COVID-Generation",doi:"10.5772/intechopen.97931",slug:"forecasting-the-long-term-effects-of-the-pandemic-on-children-towards-a-covid-generation",totalDownloads:421,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"This study focuses on mapping the existing effects of the pandemic and the measures taken to address it on the mental health of children in order to investigate the long-term consequences that it is expected to have. For infants, preschool, school and adolescent children it seems that intense stress develops for different reasons. As adults these children may experience an increased incidence of anxiety, depressive, obsessive–compulsive and personality disorders, while they are also expected to develop a strong External Locus of Control, low Faith in the Just World and low happiness. At the same time, an absence of distinction within the limits of the physical and digital world is expected. As for children with special educational needs, they are particularly affected due to the pandemic, as early diagnosis and the development of interventions to improve their educational and psychosocial progress are hampered and this might have negative long-term effects on their development. In overall, these negative effects and related experiences seem to be homogeneous across humanity for those who are currently minors and are expected to lead to the view of an autonomous generation, the COVID-generation.",signatures:"Panagiotis Pelekasis",downloadPdfUrl:"/chapter/pdf-download/76851",previewPdfUrl:"/chapter/pdf-preview/76851",authors:[{id:"349115",title:"M.Sc.",name:"Panagiotis",surname:"Pelekasis",slug:"panagiotis-pelekasis",fullName:"Panagiotis Pelekasis"}],corrections:null},{id:"76987",title:"COVID-19 and Psychological Distress among Older Adults in Ghana",doi:"10.5772/intechopen.98277",slug:"covid-19-and-psychological-distress-among-older-adults-in-ghana",totalDownloads:268,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"COVID-19, the novel of all respiratory pandemics, has since its global invasion remained a significant threat in all spheres of human endeavour. This phenomenon has led to short-term and long-term psychosocial and mental health implications for many populations, particularly vulnerable groups, of which older people form part. This paper fills the lacuna in research on how the pandemic is breeding psychological distress among older people. Cross-sectional data were obtained from an Ageing, Health, Lifestyle and Health Services (AHLHS) study conducted between June 2020 and August 2020 (N = 400) in the Ashanti and Greater Accra regions of Ghana. Sequential logistic regression models were performed to estimate the variables that predict psychological distress, whereas descriptive statistics were used to determine the extent of psychological distress among the study population. This study revealed that psychological distress was somehow prevalent, necessitating early intervention to minimise the risks of the said health risk. Additionally, gender, employment status, chronic NCDs, perceived health status and receipt of COVID-19 information were significantly associated with psychological distress among the respondents. It is necessary to employ strategies to minimise the psychological distress in Ghana during this pandemic.",signatures:"Anthony Kwame Morgan, Justin Cobbold, Beatrice Aberinpoka Awafo, Daniel Katey, Theophilus Quartey and Rahinatu Ibrahim",downloadPdfUrl:"/chapter/pdf-download/76987",previewPdfUrl:"/chapter/pdf-preview/76987",authors:[{id:"349385",title:"Mr.",name:"Anthony",surname:"Morgan",slug:"anthony-morgan",fullName:"Anthony Morgan"},{id:"416887",title:"Mr.",name:"Justin",surname:"Cobbold",slug:"justin-cobbold",fullName:"Justin Cobbold"},{id:"416888",title:"Ms.",name:"Beatrice Aberinpoka",surname:"Awafo",slug:"beatrice-aberinpoka-awafo",fullName:"Beatrice Aberinpoka Awafo"},{id:"416889",title:"Mr.",name:"Daniel",surname:"Katey",slug:"daniel-katey",fullName:"Daniel Katey"},{id:"416890",title:"Mr.",name:"Theophilus",surname:"Quartey",slug:"theophilus-quartey",fullName:"Theophilus Quartey"},{id:"416891",title:"Ms.",name:"Rahinatu",surname:"Ibrahim",slug:"rahinatu-ibrahim",fullName:"Rahinatu Ibrahim"}],corrections:null},{id:"76897",title:"Main Concerns in Times of COVID-19 in Three Groups of People: Italians, Romanian Immigrants in Italy, and Romanians in Romania",doi:"10.5772/intechopen.97858",slug:"main-concerns-in-times-of-covid-19-in-three-groups-of-people-italians-romanian-immigrants-in-italy-a",totalDownloads:280,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"This chapter is a description of results of a study conducted in Italy involving Italians (N = 491), Romanian immigrants (N = 275), and Romanians in Romania (N = 312) with aim to explore the principal sources of anxiety and uncertainty during COVID-19 pandemic, and the differences between the groups. In addition, the study analysed the role of resilience as a potential moderator between perception of sources of anxiety during COVID-19 and distress. A questionnaire was administered containing several scales. Results showed that Italians and immigrants have similar concerns and that the perception of resilience play significant role in determining emotional distress.",signatures:"Ankica Kosic and Tamara Dzamonja Ignjatovic",downloadPdfUrl:"/chapter/pdf-download/76897",previewPdfUrl:"/chapter/pdf-preview/76897",authors:[{id:"298118",title:"Dr.",name:"Tamara",surname:"Dzamonja Ignjatovic",slug:"tamara-dzamonja-ignjatovic",fullName:"Tamara Dzamonja Ignjatovic"},{id:"349395",title:"Associate Prof.",name:"Ankica",surname:"Kosic",slug:"ankica-kosic",fullName:"Ankica Kosic"}],corrections:null},{id:"77866",title:"Psychosocial Impact of Lockdown Induced Setback on Education during Pandemic in India",doi:"10.5772/intechopen.98445",slug:"psychosocial-impact-of-lockdown-induced-setback-on-education-during-pandemic-in-india",totalDownloads:241,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Educational reforms occur from time to time to keep up the pace of changing trends. The new generations of kids are exposed to modern technology at a very younger age. They are well equipped with the novel usage of digital technology to aid in a better teaching-learning process. Pandemic has invoked a lot of drastic changes in many sectors owing to changing norms and lockdown policies across the globe. In India also these lockdown policies were imposed as a measure to curtail the growing rate of infection. India is a country with a dense population with varied socio-cultural and economic differences. Closure of educational institutes adopted as a strategic measure to face the Pandemic lead to uncertainty among the stakeholders which had a huge impact on the psychosocial domain. The education sector took to the mode of digital learning by offering online classes to cater to the need of the students. Shutting down schools and educational institutes not only paralyzed the social contact a child develops on attending school but also increased the severity of screen time with absolute lack of physical activity among children. This chapter aims to explore the impact of the online mode of education and its psychosocial perspectives during the lockdown.",signatures:"Chitra Mourali",downloadPdfUrl:"/chapter/pdf-download/77866",previewPdfUrl:"/chapter/pdf-preview/77866",authors:[{id:"351967",title:"Prof.",name:"Chitra",surname:"Mourali",slug:"chitra-mourali",fullName:"Chitra Mourali"}],corrections:null},{id:"76837",title:"Psychiatric Services and Teaching during the Covid-19 Pandemic in Romania",doi:"10.5772/intechopen.97800",slug:"psychiatric-services-and-teaching-during-the-covid-19-pandemic-in-romania",totalDownloads:434,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"The Covid-19 pandemic has been declared in Romania on the 16th March 2020.The medical system reacted promptly: chronic patients had to be discharged within 48 h and further scheduled admittances were postponed, adequate epidemiological measures and circuits were organized. Anxiety, insomnia, frustration, binge eating, domestic violence were reported. The majority respected the general advises but soon, persons selected their information sources rather from social media, being victims of the infodemia and peculiar conspirationist theories. A new disorder has been described: coronaphobia. The psychiatric hospitals and outpatient settings had to reduce or innactivate their activity, switch as much as possible to TelePsychiatry. Psychiatry admittances were: onsets of psychosis, relapses of schizophrenia and alcohol, other psychoactive substances abuses, intoxications, and withdrawal states. Later, there were depressions, bipolar disorders, suicide attempts, self-harm in borderline disorder, dementia and delirium. Due to the closure of outpatient units for several months, patients visited the Emergency rooms. Personnel experienced burnout and new psychiatric pathology developed in the aftermath of Covid-19 infection. A big relief occurred with the initial vaccination of the medical staff and seniors, chronically ill persons, psychiatric patients being again left behind. Medical teaching shifted entirely to online and in 2021 the hybrid teaching system has been employed.",signatures:"Ioana Valentina Micluţia",downloadPdfUrl:"/chapter/pdf-download/76837",previewPdfUrl:"/chapter/pdf-preview/76837",authors:[{id:"215988",title:"Prof.",name:"Ioana",surname:"Valentina Micluţia",slug:"ioana-valentina-miclutia",fullName:"Ioana Valentina Micluţia"}],corrections:null},{id:"76488",title:"Psychological Aspects of Neuroinflammatory Disorders in COVID-19 Era",doi:"10.5772/intechopen.97629",slug:"psychological-aspects-of-neuroinflammatory-disorders-in-covid-19-era",totalDownloads:300,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Although the COVID-19 pandemic was initially manifested as a contagious respiratory infection, its other aspects quickly became apparent. Accordingly, the disease could affect various organs such as skin, digestive system, and the central nervous system. Apart from these diverse manifestations, it was rapidly cleared that the virus could potentially play a role in causing a wide range of autoimmune diseases. Moreover, various anthropological aspects of COVID-19 and its effects on human life were considered. In this regard, one of the important issues is its psychological effects, not only on the population of healthy people, but also on people suffering from underlying diseases. Inflammatory diseases of the central nervous system are included as one group of these diseases. Since these diseases can cause many psychological problems in patients, it is very important to pay attention to them during the COVID-19 pandemic. In the following section, the psychological aspects of COVID-19 in patients with neuroinflammatory diseases are described.",signatures:"Abdorreza Naser Moghadasi",downloadPdfUrl:"/chapter/pdf-download/76488",previewPdfUrl:"/chapter/pdf-preview/76488",authors:[{id:"346561",title:"Assistant Prof.",name:"Abdorreza",surname:"Naser Moghadasi",slug:"abdorreza-naser-moghadasi",fullName:"Abdorreza Naser Moghadasi"}],corrections:null},{id:"77510",title:"Local Knowledge, Community Experiences, Nature, Collaboration, and Resilience in Times of Pandemic, Uncertainty, and Climate Change in the Anthropocene Era",doi:"10.5772/intechopen.98481",slug:"local-knowledge-community-experiences-nature-collaboration-and-resilience-in-times-of-pandemic-uncer",totalDownloads:288,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"The pandemic afflicting the world is accompanied by a social, economic, political, cultural, and climatic multi-crisis. It is the crisis of the Anthropocene Era and modern paradigms. Modern society is in a complex situation. The responses to the multicrisis, including the pandemic, will probably come from the revalorization and resignification of experiences and socioecological knowledge of communities. Their historical experiences, currently fragmented by modernization processes, will be able to intercommunicate and, with resilient energy, open new possibilities for human and planetary life. It will be a great transformation, in which old and new models of development will be in tension. These tensions will also be expressed in the form of social and political radicalization and result in conflicts over natural resources, especially water, natural forests, ecosystems, and productive land. Human and planetary life is seriously threatened. Intellectual and scientific activity must connect with the ecological knowledge of local communities to defend human and natural life.",signatures:"Jorge Rojas Hernández, Patricio Silva Ávila and Ricardo Barra Ríos",downloadPdfUrl:"/chapter/pdf-download/77510",previewPdfUrl:"/chapter/pdf-preview/77510",authors:[{id:"291624",title:"Dr.",name:"Jorge",surname:"Rojas Hernández",slug:"jorge-rojas-hernandez",fullName:"Jorge Rojas Hernández"},{id:"414334",title:"Prof.",name:"Ricardo",surname:"Barra",slug:"ricardo-barra",fullName:"Ricardo Barra"},{id:"423510",title:"Dr.",name:"Patricio",surname:"Silva Ávila",slug:"patricio-silva-avila",fullName:"Patricio Silva Ávila"}],corrections:null},{id:"75425",title:"Buddhist Monastery, Amulet, Spiritual Support and COVID-19 Outbreak",doi:"10.5772/intechopen.96496",slug:"buddhist-monastery-amulet-spiritual-support-and-covid-19-outbreak",totalDownloads:372,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"COVID-19 is an important global problem. The disease causes illness and results in anxious state and panic. It also has a lot of socioeconomic impact worldwide. The supports for the affected persons are by several partners including religious unit. The religious unit can play important social welfare role to support the local people. In Indochina, many local Buddhist monasteries act this role. This is an interesting anthropological phenomenon. Many monasteries issue amulet as gimmicks for sale to the donor. The donor buys amulets for spiritual support during frustrate period and the monastery receive money for its welfare function. This is an interesting social sustainability phenomenon.",signatures:"Rujitika Mungmunpuntipantip and Viroj Wiwanitkit",downloadPdfUrl:"/chapter/pdf-download/75425",previewPdfUrl:"/chapter/pdf-preview/75425",authors:[{id:"347021",title:"Dr.",name:"Rujittika",surname:"Mungmunpuntopantip",slug:"rujittika-mungmunpuntopantip",fullName:"Rujittika Mungmunpuntopantip"},{id:"347026",title:"Prof.",name:"Viroj",surname:"Wiwanitkit",slug:"viroj-wiwanitkit",fullName:"Viroj Wiwanitkit"}],corrections:null},{id:"76968",title:"In the Darkness of This Time: Wittgenstein and Freud on Uncertainty",doi:"10.5772/intechopen.98381",slug:"in-the-darkness-of-this-time-wittgenstein-and-freud-on-uncertainty",totalDownloads:462,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Both Wittgenstein and Freud experienced the crisis of humanism resulting from the first and second world wars. Although they were both considered to be influential figures, they hardly investigated the ways in which people could cope with the consequences of these crises. However, Wittgenstein and Freud did suggest ways of understanding uncertainties caused by real life events, as well as by the nature of human thought processes. This article will explore the therapeutic ways of dealing with uncertainties common to both thinkers and the different concepts facilitating their methodologies. The central contention of this article is that both Wittgenstein and Freud developed a complex methodology, acknowledging the constant and unexpected changes humans have deal with, whilst also offering the possibility of defining “hinge propositions” and “language-games” which can stabilize our consciousness.",signatures:"Dorit Lemberger",downloadPdfUrl:"/chapter/pdf-download/76968",previewPdfUrl:"/chapter/pdf-preview/76968",authors:[{id:"325725",title:"Dr.",name:"Dorit",surname:"Lemberger",slug:"dorit-lemberger",fullName:"Dorit Lemberger"}],corrections:null},{id:"77080",title:"Human Reconfigurations: Conversations on Being Therap(ist)eutic in Time of Covid",doi:"10.5772/intechopen.98317",slug:"human-reconfigurations-conversations-on-being-therap-ist-eutic-in-time-of-covid",totalDownloads:271,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"In this paper the authors’ aim is to reflect on the impact the Sars-CoV-2 Pandemic has had and is still having on our external and internal reality, in terms of individual and collective implications. In an open dialog with colleagues and patients, through a psychoanalytic viewpoint capable of respecting the suffering and the solutions identified by the Ego-subject within the “therapeutic dance”, it was possible during this period to observe movements and processes underlying these changes. Throughout the paper, the authors highlight both difficulties and resources that the patients put in play within the relational space and the need to “reconfigure” them; our focus is on the creativity and the repercussions this event, significant for the majority of the Society, has had on the practices and beliefs of each of us. The peculiar experience of loneliness and isolation, faced during this pandemic emergency, has profoundly transformed and shaped our living space, demanding a collective reorganization of the social space and thus forcing us to rethink our humanity. In the relational exchange, the possibility of finding one’s own space to exist and to inhabit one’s present, can be unfolded. A shared resilience is necessary to face current challenges.",signatures:"Jolanda Spoto, Valentina Stirone and Romina Coin",downloadPdfUrl:"/chapter/pdf-download/77080",previewPdfUrl:"/chapter/pdf-preview/77080",authors:[{id:"347881",title:"Ph.D.",name:"Romina",surname:"Coin",slug:"romina-coin",fullName:"Romina Coin"},{id:"348271",title:"Dr.",name:"Spoto",surname:"Jolanda",slug:"spoto-jolanda",fullName:"Spoto Jolanda"},{id:"416592",title:null,name:"Valentina",surname:"Stirone",slug:"valentina-stirone",fullName:"Valentina Stirone"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:[{id:"51",label:"edited by 2015 nobel prize nominee"}]},relatedBooks:[{type:"book",id:"8262",title:"The New Forms of Social Exclusion",subtitle:null,isOpenForSubmission:!1,hash:"29bf235aa7659d3651183fe9ea49dc0d",slug:"the-new-forms-of-social-exclusion",bookSignature:"Rosalba Morese and Sara Palermo",coverURL:"https://cdn.intechopen.com/books/images_new/8262.jpg",editedByType:"Edited by",editors:[{id:"214435",title:"Dr.",name:"Rosalba",surname:"Morese",slug:"rosalba-morese",fullName:"Rosalba Morese"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7818",title:"Social Isolation",subtitle:"An Interdisciplinary View",isOpenForSubmission:!1,hash:"db3b513d7d35476f333a0d4a3147935b",slug:"social-isolation-an-interdisciplinary-view",bookSignature:"Rosalba Morese, Sara Palermo and Raffaella Fiorella",coverURL:"https://cdn.intechopen.com/books/images_new/7818.jpg",editedByType:"Edited by",editors:[{id:"214435",title:"Dr.",name:"Rosalba",surname:"Morese",slug:"rosalba-morese",fullName:"Rosalba Morese"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6934",title:"Psycho-Social Aspects of Human Sexuality and Ethics",subtitle:null,isOpenForSubmission:!1,hash:"44731b106aa0d1ab5c64a7394483c7d5",slug:"psycho-social-aspects-of-human-sexuality-and-ethics",bookSignature:"Dhastagir Sultan Sheriff",coverURL:"https://cdn.intechopen.com/books/images_new/6934.jpg",editedByType:"Edited by",editors:[{id:"167875",title:"Dr.",name:"Dhastagir Sultan",surname:"Sheriff",slug:"dhastagir-sultan-sheriff",fullName:"Dhastagir Sultan Sheriff"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10450",title:"Evolutionary Psychology Meets Social Neuroscience",subtitle:null,isOpenForSubmission:!1,hash:"bd4df54e3fb185306ec3899db7044efb",slug:"evolutionary-psychology-meets-social-neuroscience",bookSignature:"Rosalba Morese, Vincenzo Auriemma and Sara Palermo",coverURL:"https://cdn.intechopen.com/books/images_new/10450.jpg",editedByType:"Edited by",editors:[{id:"214435",title:"Dr.",name:"Rosalba",surname:"Morese",slug:"rosalba-morese",fullName:"Rosalba Morese"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. 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Salih"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],ofsBooks:[]},correction:{item:{id:"79356",slug:"corrigendum-to-analytical-study-of-environmental-impacts-and-their-effects-on-groundwater-hydrology",title:"Corrigendum to: Analytical Study of Environmental Impacts and Their Effects on Groundwater Hydrology",doi:null,correctionPDFUrl:"https://cdn.intechopen.com/pdfs/72413.pdf",downloadPdfUrl:"/chapter/pdf-download/72413",previewPdfUrl:"/chapter/pdf-preview/72413",totalDownloads:null,totalCrossrefCites:null,bibtexUrl:"/chapter/bibtex/72413",risUrl:"/chapter/ris/72413",chapter:{id:"68077",slug:"analytical-study-of-environmental-impacts-and-their-effects-on-groundwater-hydrology",signatures:"Muhammad Salik Javaid, Laila Khalid and Muhammad Zeshan Khalid",dateSubmitted:"April 29th 2019",dateReviewed:"June 12th 2019",datePrePublished:null,datePublished:"March 4th 2020",book:{id:"8602",title:"Groundwater Hydrology",subtitle:null,fullTitle:"Groundwater Hydrology",slug:"groundwater-hydrology",publishedDate:"March 4th 2020",bookSignature:"Muhammad Salik Javaid",coverURL:"https://cdn.intechopen.com/books/images_new/8602.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"208759",title:"Dr.",name:"Muhammad Salik",middleName:null,surname:"Javaid",slug:"muhammad-salik-javaid",fullName:"Muhammad Salik Javaid"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"208759",title:"Dr.",name:"Muhammad Salik",middleName:null,surname:"Javaid",fullName:"Muhammad Salik Javaid",slug:"muhammad-salik-javaid",email:"msalikj@hotmail.com",position:null,institution:{name:"Abasyn University",institutionURL:null,country:{name:"Pakistan"}}}]}},chapter:{id:"68077",slug:"analytical-study-of-environmental-impacts-and-their-effects-on-groundwater-hydrology",signatures:"Muhammad Salik Javaid, Laila Khalid and Muhammad Zeshan Khalid",dateSubmitted:"April 29th 2019",dateReviewed:"June 12th 2019",datePrePublished:null,datePublished:"March 4th 2020",book:{id:"8602",title:"Groundwater Hydrology",subtitle:null,fullTitle:"Groundwater Hydrology",slug:"groundwater-hydrology",publishedDate:"March 4th 2020",bookSignature:"Muhammad Salik Javaid",coverURL:"https://cdn.intechopen.com/books/images_new/8602.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"208759",title:"Dr.",name:"Muhammad Salik",middleName:null,surname:"Javaid",slug:"muhammad-salik-javaid",fullName:"Muhammad Salik Javaid"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"208759",title:"Dr.",name:"Muhammad Salik",middleName:null,surname:"Javaid",fullName:"Muhammad Salik Javaid",slug:"muhammad-salik-javaid",email:"msalikj@hotmail.com",position:null,institution:{name:"Abasyn 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Beauty and attractiveness have occupied human minds for millennia and have influenced the outcomes of our social interactions. Beauty has been a topic of discussion ever since the dawn of civilization as demonstrated by the works of ancient philosophers and thinkers, as well as by modern scholars and intellectuals. The present book intends to provide the reader with a comprehensive overview of the state of art in beauty and attraction studies, by using a multidisciplinary approach and incorporating different points of view, from evolution and biology to culture and arts. The chapters in this book will cover topics including evolutionary approaches to aesthetics and attractiveness, the influence of beauty in the understanding of the outside world, and how it influences our social and interpersonal decision makings, cross-cultural similarities and differences in attractiveness perception and preferences, aesthetics in visual arts, as well as, beauty as supernormality.
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Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"71286",title:"Categorizing Patient Disease into ICD-10 with Deep Learning for Semantic Text Classification",doi:"10.5772/intechopen.91292",slug:"categorizing-patient-disease-into-icd-10-with-deep-learning-for-semantic-text-classification",body:'\nIt has been found out that the analysis of the big EHR can help accomplish precision medicine for patients to improve the quality of human healthcare. In EHR analysis, there are a lot of applications that need to categorize each patient’s disease into the corresponding category with respect to a medical coding standard. The automatic categorization is very desirable for the massive EHR data sets. In this paper, we develop deep learning algorithms for semantic text classification of EHR. Our categorization system consists of four core components to accomplish the disease categorization. Firstly, by using domain knowledge of medical informatics and techniques of information fusion, we construct structured & meaningful patients’ clinic profiles from the scattered and heterogeneous medical records such as inpatient and outpatient records, lab tests, treatment plans, and doctors’ prescriptions for medications in the EHRs. This makes it possible for us to leverage the insights from the big data with artificial intelligence (AI) algorithms. Secondly, we extract each patient’s historical disease descriptions in the clinic profiles and take each of them as a document for categorization. Thirdly, we use NLP algorithms for document tokenization and vector representation when necessary. The last component is to train the predictive model based on supervised classification to categorize each disease into one of the 26 categories according to the first-level disease categories of the 10th version of the International Classification of Diseases (ICD-10) and Related Health Problems to standardize medical records [1] through text data categorization using deep learning algorithms such as the CNN, LSTM, and GRU neural networks. Experiments of comprehensive studies show that the CNN algorithm outperforms the other deep learning algorithms, and it generates much better results than the traditional machine learning algorithms for the same data set according to the quantitative metric of F1-score.
\nOur contributions are demonstrated in the following two aspects:
We construct the patients’ individual clinic profiles from the scattered and heterogeneous clinic records and tables in real EHRs with our medical domain knowledge together with medical informatics for medical information processing. The constructed clinic profiles make it feasible for us to generate actionable intelligence from the unstructured EHR raw data sets using machine learning, NLP and artificial intelligence algorithms (AI).
We design and train predictive models with NLP, embedded representations, and deep neural network algorithms to categorize patients’ diseases into ICD-10 standard.
The remaining of this paper is organized as follows. The research methodology is discussed in detail in Section 2. The experimental results are presented in Section 3, and the conclusions of the paper are made in Section 4 together with some discussions and the direction of future work.
\nThis research consists of 4 components for the categorization of EHRs: problem definition and data preparation and collection from EHR, text data extraction from the prepared and collected data, the tokenization of the Chinese documents using NLP, and supervised deep learning algorithms with embedded vector representations for tokens/words as inputs to the neural network architectures for the semantic categorization of each patient’s disease symptom description into ICD-10 standard.
\nFor the research of Chinese medical healthcare data analysis, we have obtained the Chinese EHRs from 10 Chinese hospitals in Shandong Province, China. These EHRs contain 179 scattered and heterogeneous clinic records and tables, for example, the patients’ admission records, outpatient records, inpatient hospitalization records, all kinds of lab tests, prescriptions for medication information, surgery information, hospital and doctor information, patients’ personal information and their family information. However, the data quality is not satisfactory because it is still at the early stage for the Chinese hospitals to create the EHRs for patients, and most of the doctors are more willing to write notes on their patients’ record books rather than to type their notes in the computer systems. As a result, in the 179 clinic tables, only a portion of them contains useful information and there are too many non-filled columns in many tables. After the preprocessing process, only 85 tables are selected and even in these 85 tables, many records do not contain useful information and we need to do additional processing such as data governance [2] for some applications. We then construct individual clinic profiles for patients by using the method of database information fusion on the scattered and heterogeneous 85 tables according to the medical domain knowledge. The constructed clinic profiles contain each patient’s individual symptom descriptions, diagnosis records, lab tests, doctor’s treatment plans, and prescriptions for each office visit or each day’s hospitalization, forming the clinic profiles. The clinic profile is very useful for all applications about the EHR analysis with machine learning. But for this categorization task, we only extract the disease symptom description of individual patients from the constructed clinic profiles, and then we use NLP, machine learning, and AI algorithms to analyze them. The number of valid records with non-empty symptom description in the EHR is significantly reduced after all preprocessing steps.
\nWhen we use machine learning for document categorization, documents first need to be tokenized into individual words or tokens. For traditional machine learning algorithms, documents are represented as feature vectors with the bag of words (BOW) feature engineering method. For deep learning algorithms, each document is the input of the deep learning architecture with individual tokens represented as word embeddings. So, we first tokenize each Chinese document into a collection of terms. The tokenization of Chinese documents is very different from that of English, which can be accomplished through the delimiters between terms. In this work, we use the Han LP, an open source tokenization tool for tokenizing Chinese documents. After some preprocessing for the tokens, we then represent each word with the pre-trained embedded vector representation with the language model of distributed representation learning algorithm word2Vec [3].
\nBoth traditional one-hot vector representation and BOW-based TF-IDF or binary feature representation for words have a lot of limitations for document classification. They are constrained with problems of high dimensionality and sparsity for the feature vectors and they are not able to capture any semantic information from the words due to the mutual orthogonality of the individual words with such representations. The motivation of using the distributed embedded vector representation is to reduce the dimensionality of the vector while at the same time providing semantic information of words. The word2Vec algorithm [3] is a kind of distributed representation learning algorithm for the language model to capture each word’s semantic information through the embedded dense vectors so that semantically similar words can be inferred from each other. There are two different models in the word2Vec algorithm and they are the continuous bag-of-words (CBOW) model and the skip-gram model as shown in \nFigures 1\n and \n2\n, respectively.
\nThe CBOW model in word2Vec.
The skip-gram model in word2Vec.
For a sentence, the CBOW model is used to predict the current word from its left side and right side context words, which are within a window centered at the current word. On the other hand, the skip-gram model is used to predict the surrounding context words in a sentence for the given current word with the context words within a window whose center is at the current word. The Word2vec model can be trained in two different ways: using the hierarchical softmax algorithm or using the negative sampling method. For the hierarchical softmax algorithm, we first get the vocabulary of the corpus and then we create a binary Huffman tree for all words according to their frequencies of occurrences, and all words are the leaf nodes of the Huffman tree. The main benefit of the Huffman tree is that it offers the convenient access of the frequent information. In the Huffman tree, the high-frequency words have short paths from the root of the tree to the individual leaf nodes, and the low-frequency words have long paths, thus accomplishing optimal encoding performance from the viewpoint of bit-rate. In the original softmax algorithm, as shown in formula (1), when updating one word’s vector during the training process, all words’ vectors should be involved in the calculation and the computational complexity is accordingly as high as O(N). On the other hand, in the hierarchical softmax, when updating the embedded vector for a leaf node in the tree, only the leaf node and non-leaf-nodes on the path from the root of the tree to the leaf node need to be involved in the calculation. As a result, by using the Huffman tree based hierarchical softmax algorithm, we can significantly reduce the computational complexity from O(N) to O(logN).
\nAs for the negative sampling, it does not need all words’ vectors to be involved in updating a word’s vector in the back-propagation process and it only needs to sample a few negative pairs like (central word, [negative context words]) for the central word of each positive pair (central word, positive context word) in the corpus. Furthermore, to improve the vector quality of low-frequency words, the high-frequency words are down-sampled and the low-frequency words are up-sampled by using a method called frequency lifting. This helps because otherwise the high-frequency words are more likely to be sampled than the low-frequency words for updating their vectors. With the embedded representation from Word2Vec, each word in the corpus can be represented by a unique low-dimensional dense vector. \nFigures 3\n and \n4\n demonstrate the clustering feature of this kind of word embeddings that if some words are semantically close to each other, their representations in the vector space are close to each other.
\nThe clustering characteristics of embedded vector representations of semantically similar words in the dense vector space.
The similar sub-structures of the embedded vectors in the dense vector space between semantically meaningful country-capital word pairs with the courtesy of Mikolov etc. [
In this work, we build the predictive models based on deep learning techniques with the supervised learning methodology. To this end, we train four different deep learning models for performance comparison: the CNN with max pooling and k-max pooling, respectively, LSTM, and GRU.
\nThe CNN is one of the popular deep neural network algorithms for both NLP and computer vision applications. The CNN architecture contains the layers of automatic feature extraction, feature selection, and the pattern classification. It has attracted great attention in text classification [4] and computer vision [5]. As demonstrated in \nFigure 5\n, different channels of the data can be used as inputs of the CNN architecture for feature extraction and feature selection via convolutional operations together with the pooling process and nonlinear activation. For computer vision applications, the R, G, B colors of an image are usually used as CNN’s inputs. For text classification applications, a matrix of word embeddings stacked by the words’ embedded vectors according to the order of the words in the sequence, is usually used as the input of the CNN architecture. The embeddings can be either from word2Vec, one-hot representation and/or other vector representations of words, forming different channels of the representation of text data. Within the CNN architecture, each channel of the texts is represented as a matrix, in which, the rows of the matrix represent the sequence of words according to their order, and each row is a word’s vector representation with the number of columns being the dimension size of the embedded vector space. For feature extraction, the matrix is convolved with some filters of different sizes, respectively. All filters have the same number of columns as the words’ embeddings.
\nText classification using the CNN architecture with courtesy of Kim [
For text classification, the main idea of CNN using different sizes of filters is pretty much like that for computer vision. It is for the purpose of extracting the semantic features (patterns) of different N-Grams characterized by the filters. The different filter sizes correspond to different N-Grams. The words’ vector representations can be either from the pre-trained word embeddings, for example, the word2Vec embeddings, or randomly initialized. For the randomly initialized words vectors, they are iteratively updated in the back-propagation process during the training stage until the training process is done, and this is another way of representation learning. For the clear illustration, we assume the filter
where
In addition to the commonly used max-pooling for CNN, another pooling method is the k-max pooling CNN [6], in which for each feature map obtained from the convolution of a filter
RNNs are very efficient for modeling the time series data for prediction and forecasting tasks. As shown in \nFigure 6\n, the chain-link RNN architecture consists of a sequence of neural network modules sharing the same parameters. Each module is used to analyze the information at a time in the sequence. At any time, the RNN system takes as inputs the information
The RNN structure with courtesy of Colah [
The typical NLP applications of using RNN are text classification, sentence generation, and language translation. With the sequence modeling, a sentence is taken to be an ordered time series with the starting time 0 at the first word and at time
The LSTM networks are a special kind of RNNs, capable of learning the long-term dependencies in the input data. LSTMs are explicitly designed to avoid the vanishing gradient problem in learning the long-term dependencies in the data and they have achieved great success in sentiment analysis, text classification, and language translation. As shown in \nFigure 7\n, the LSTM architecture is very similar to that of the RNN. It is a chain of repeating modules, each of which is a modified version of that in RNNs.
\nThe LSTM architecture with courtesy of Colah [
By comparing a module at time
The architecture of gated recurrent units (GRU) [9] is a simplified version of the LSTM architecture with only two gates, a reset gate r and an update gate
The GRU structure with courtesy of Colah [
The ICD-10 coding system is essentially a tree-like hierarchical structure with 3 layers to encode patients’ diseases. For a larger layer number in the tree, it categorizes diseases into finer disease categories. In the first layer, it only classifies disease symptoms into 26 coarse disease categories, but, in the second layer, it can classify disease symptoms into more than 500 disease categories, and in the third layer, it can accomplish the categorization for about 21,000 diseases. But for the time being, for supervised machine learning, we can only train a model to classify patient diseases into one of the 26 categories corresponding to the first layer of ICD-10 coding system. This is for the fact that as the number of classes increases for supervised machine learning, the required annotated training data increases significantly, however we do not have so many patient records now. Furthermore, our current EHR data is very unbalanced and most of the patients’ diseases belong to popular diseases. For the 26 disease categories in the first-layer of ICD-10, our EHR system only has sufficient disease examples for 14 popular disease categories, but we do not have sufficient disease examples for the rest 12 unpopular disease categories. In this paper, we can only annotate disease examples for the 14 popular disease categories to train a 14-class classifier.
\nIn this paper, we use the quantitative metrics to measure the performance of the models. They are the precision, recall, and F1-score, and they are calculated in the following way:
\nwhere
For the fair performance comparison of deep learning algorithms with traditional machine learning algorithms, we compare the deep learning algorithms with what we have done with SVM [10]. For SVM, we use two kinds of vector representations for document representation: the BOW vectors and the embedded vectors. The BOW vectors can be further separated into TF-IDF weighted vectors and binary vectors. The embedded vectors can be separated into two forms: the averaged word embeddings of the pre-trained word embeddings from word2Vec to represent a document, and the doc2Vec vectors from the PV-DM model [11], respectively. As a result, we totally use 4 document representations as the inputs for SVM. For BOW method using both the TF-IDF weighted and binary vector representations, we use the keywords as the features instead of the individual tokenized words, and the dimensionality of the feature vectors is 53,039 after performing some preprocessing to filter out the infrequent keywords. When optimizing the word2Vec to get the pre-trained word embeddings, we have tried 4 models and they are the Skip-gram with the hierarchical softmax, Skip-gram with the negative sampling, CBOW with the hierarchical softmax, and CBOW with the negative sampling. We select the CBOW with the negative sampling to get the pre-trained word embeddings, and the feature vector of the SVM classifier is obtained as discussed above. The values for the optimized hyperparameters are: the number of epochs is set 10, minibatch is 32, dimension size of embeddings is 100, low frequency threshold for sampling is 1e−5, window size is 3, and 5 samples are used for negative sampling,
\nTo train the multi-class SVM classifier, we use the grid search with the regularity \n
Input vector(s) | \nF1-score | \nPrecision | \nRecall | \n
---|---|---|---|
Binary BOW | \n0.76 | \n0.76 | \n0.76 | \n
TF-IDF BOW | \n0.76 | \n0.76 | \n0.76 | \n
Avg. Word2Vec | \n0.70 | \n0.71 | \n0.71 | \n
Doc2Vec | \n0.64 | \n0.65 | \n0.65 | \n
The prediction results of 14-class SVM classifier with L1 regularity.
Input vector(s) | \nF1-score | \nPrecision | \nRecall | \n
---|---|---|---|
Binary BOW | \n0.76 | \n0.76 | \n0.76 | \n
TF-IDF BOW | \n0.77 | \n0.77 | \n0.77 | \n
Avg. Word2Vec | \n0.70 | \n0.71 | \n0.71 | \n
Doc2Vec | \n0.64 | \n0.65 | \n0.65 | \n
The prediction results of 14-class SVM classifier with L2 regularity.
To train the multi-class CNN classifier, we use the pretrained word embeddings of word2Vec as the inputs of words’ embeddings for the CNN architecture. For each filter size, we use 100 convolutional filters to extract features. The crawled Chinese medical documents are used as the corpus for training the word2Vec algorithm to get the pre-trained word embeddings. The optimized hyperparameter values of the CNN are: epoch size is 40, batch size is 20, dropout probability is 0.5, the \n
To train the multi-class LSTM and GRU classifiers, to make sure the deep learning models are trained in an optimal way, we have tried different optimization methods, such as the Adam, AdaDelta, and RMSprop. We find that the RMSprop optimizer works best for our data set. We set the hyperparameters to be: batch size 32, hidden size 64, epoch size 50, the dimension of word embeddings 300, dropout 0.5, and L2 regularization lambda 0.7. The LSTM and GRU algorithms are implemented in Python and Tensorflow. Since the training process for both LSTM and GRU is very time consuming for the use of 6000 training and validation examples for each disease category, for computational efficiency, we shorten each disease description to be 700 words. This assumes that customers’ disease symptoms are mainly contained in the first 700 words of each note. Otherwise the memory requirement is very huge. This assumption is of course not 100% correct, but it greatly helps speed up the training process.
\nIn this paper, the NLP, deep learning algorithms, and the algorithm of SVM are implemented in Python, Tensorflow, and the open source software of machine learning library Sklearn. The results of CNN, LSTM and GRU algorithms are displayed in \nTable 3\n, from which we can see that the CNN algorithm with max-pooling works best.
\nInput vector(s) | \nF1-score | \nPrecision | \nRecall | \n
---|---|---|---|
Word2vec + CNN + k-max pool | \n0.74 | \n0.73 | \n0.73 | \n
Word2vec + CNN + Max pool | \n0.80 | \n0.80 | \n0.81 | \n
Word2vec + LSTM | \n0.74 | \n0.75 | \n0.74 | \n
Word2vec + GRU | \n0.74 | \n0.75 | \n0.74 | \n
The prediction results of 4 deep learning algorithms.
In this paper, we develop NLP and deep learning algorithms to categorize patients’ diseases according to the ICD-10 coding standard. Through comparative studies, we find out that the CNN model achieves better performance than the RNN-based LSTM and GRU models. The CNN model also outperforms the popular traditional machine learning model SVM for the same data set. In the future, we are going to investigate the transfer learning and deep learning algorithms with the attention mechanism for semantic text classification. At the same time, it is very necessary for hospitals and doctors to provide high-quality medical healthcare data and the high-quality EHR data is equally important as the medical services provided to patients.
\nThe authors would like to thank the support from the Health Planning Commission of Shandong Province, China.
\nTraditional cryopreservation techniques are widely used in assisted reproductive technology (ART) programs all over the world; however, vitrification is a novel technique and has become a quickly growing alternative method for the cryopreservation of human spermatozoa in the past decade. Sperm vitrification usually requires a small loading volume of sample to achieve an extremely high cooling rate. Human sperm vitrification has been the most commonly used way to preserve the fertility of males, including those with severe oligospermia or azoospermia patients, who have undergone a TESE/micro-TESE procedure, which has yielded a small number of spermatozoa. However, in the past few years, many new designs of larger volumes have been developed and have displayed promising results. This review summarizes the recent researches on human sperm vitrification, including comparison studies of conventional cryopreservation methods like slow freezing and vitrification, descriptions of different types of cryoprotectants, methods of human sperm vitrification, as well as the warming, storage of vitrified samples, contamination risk and control during sperm vitrification.
There are several different cryopreservation methods, including slow freezing (0.5–0°C/min), rapid freezing (50–400°C/min), ultra-rapid freezing (~2500°C/min), and vitrification (~20,000°C/min), applied accordingly depending on the freezing speed and cryoprotectant concentration and temperature reduction [1]. The principles of cryopreservation are based on the laws of thermodynamics. Sperm has been shown to be sensitive to exposure to high concentrations of cryoprotective agents. Freezing media for human sperm vitrification is significantly different from cryopreservation solutions for oocytes and embryos. Contrary to the slow freezing process, the vitrification process is based on an extremely high cooling rate that prevents intracellular ice crystallization and produces an amorphous, glass-like solid state.
The greatest challenge the cells are facing during the freezing and warming processes is cell damage caused by ice crystals forming a temperature range between −15 and − 60°C. At temperatures between −5 to −15°C, extracellular ice formation occurs and develops an extracellular solid phase. Meanwhile, the inside of the cell remains supercooled, which has a high chemical potential and diffuses out of the cell osmotically. Extracellularly hypertonic results in further removal of water from cells causing almost complete dehydration. The composition of the cryopreservation media plays a vital role in the freezing techniques, fast or slow. Permeable cryoprotectants, including glycerol, ethylene glycol, 1,2 propanediol, and dimethyl sulfoxide (DMSO), are typically used in the cryopreservation of human spermatozoa. Due to their lipophilic properties, they cross the cell membrane, creating an osmotic gradient caused by water outside of the cell. Sperm have been shown to be particularly sensitive to high concentrations of cryoprotectants that are routinely used for oocytes and embryos. Non-permeable cryoprotectants, including sucrose, glucose, and trehalose etc., are of high molecular weight, and consequently are not able to penetrate the cell membrane. They are not directly toxic to sperm, but they nonetheless cause damage due to the osmotic shock encountered during addition and removal. Vitrification does not require an osmotic balance during the freezing period of the cells, as fast dehydration occurs with a super high freezing speed and a hyperosmolar medium. During the process, as the viscosity of the solution increases, the molecules are immobilized and the liquid passed to a solid glass-like phase without the formation of ice crystals in both the intracellular and extracellular environment while displacing the water from the cell. For the vitrification of human sperm, the cryoprotectant-free vitrification method has been developed to reduce cryo-injuries [2].
Both slow freezing and vitrification have advantages and disadvantages which can be found in Table 1. One way to investigate the difference between slow freezing and vitrification is directly compared the two methods using the same semen samples in the same study [3]. With 57 human semen samples, Saritha and Bango et al. discovered no substantial motility differences between the two methods [4]. Zhu et al. used 58 washed human semen samples to compare the efficiency of the slow freezing method versus the vitrification process. No differences in motility or DNA stability were found in this study, however, higher progressive motility, plasma membrane, and acrosome integrity were found in the vitrification group with optimal sucrose concentration than in the slow-freezing group [5]. Recently, Pabon et al. compared the efficiency of vitrification versus slow freezing. They found that vitrification resulted in better motility recovery and higher mitochondrial activity compared to slow freezing [6]. Karthikeyan et al. conducted a comparison study using 20 severe oligoasthenozoospermia samples and found higher motility and vitality using vitrification than slow freezing [7]. Spis et al.’s study with one epididymal and one testicular sperm sample demonstrated that vitrification had higher mitochondrial membrane potential and motility in both samples than slow freezing [8]. A systematic meta-analysis review study conducted by Li et al. included a total of 2428 published articles and 13 randomized controlled trials containing 486 vitrified and 486 slow-freezing sperm samples [9]. They concluded that although the efficacy of vitrification varied by vitrification protocols and sample quality, the vitrification method was superior to slow freezing regarding the post-thaw total motility and progressive motility [9]. Taken together, human sperm vitrification has shown higher potential compared to slow freezing, although the vitrification procedures need further to be optimized and standardized for a more definitive conclusion.
Slow freezing | Vitrification | |
---|---|---|
Cryoprotectants | Glycerol (5–10%), TEST yolk buffer (12% glycerol), IUI -ready cryoprotectant (HEPES-buffered human tubal fluid with 1% human serum album, 4% sucrose, and 6% glycerol) | Glycerol (5–10%), some vitrification methods are free of permeable cryoprotectants |
Standardized protocol | Yes | No |
Cryopreservation device | Cryovial | Cryoloop, spermVD, cryotip, cryotube, cryogenic Vial 0.25 ml |
Food and Drug Administration (FDA) approved | Yes | No |
Validated for human sperm cryopreservation and storage | Yes | No |
Current clinically applied populations | Male with normal sperm count (>15 million sperm per milliliter) | Male with severe oligospermia or azoospermia who have undergone a TESE/micro-TESE procedure which has yielded a small number of spermatozoa. |
Comparison of slow freezing vs. vitrification of human spermatozoa.
A recent review, including all the previous methods, techniques, and devices for vitrification of human spermatozoa, concluded that the universal method/platform has yet to be developed [3]. Novel solutions specially designed to vitrify a small number of spermatozoa needed to be further explored [10]. Table 2 summarizes the various methods of sperm vitrification and warming which have been developed in the past decades.
Vitrification | Warming | Reference | |
Device | Cyrotube 0.85 ml | Warmed at room temperature 30–45 min. | [11] |
Medium | Glycerol | ||
Procedure | Room temperature 10 min, plunged into liquid nitrogen | ||
Device | Cryogenic Vial 0.25 ml | Warmed in 42°C water bath 1 min, then 37°C water bath till melted. | [5] |
Medium | Permeable cryoprotectant free | ||
Procedure | Room temperature 1 min, plunged into liquid nitrogen | ||
Device | 1.5 ml straw | Warmed in 42°C medium 20 seconds. | [12] |
Medium | Permeable cryoprotectant free | ||
Procedure | Room temperature 10 min, loaded 100 μl in a straw, plunged into liquid nitrogen | ||
Device | Collector-grid 5–10 μl drop | Warmed in 44°C medium 3 min. | [6] |
Medium | Permeable cryoprotectant free. | ||
Procedure | Room temperature, plunged into liquid nitrogen | ||
Device | Cryovial. | Quickly submerging the sample in 5 ml G-IVF Plus medium prewarmed to 37°C with gentle agitation. After incubation at 37°C for 5 min, the post-thaw sperm suspension was centrifuged at 300 g for 5 min and resuspended in 100 μl G-IVF Plus medium. | [13] |
Medium | Trehalose (0.5 mol l − 1), glycine (100 mmol l − 1) and human serum albumin (1% [w/v]) | ||
Procedure | The vitrification medium was slowly added to human semen sample at a 1:1 dilution, and the resultant suspension was incubated at 25°C for 5 min. Approximately 25 μl of aliquots of the sperm suspension were dropped directly into medical-grade liquid nitrogen free from contaminants which resulting in the immediate formation of a 25 μl floating sphere that solidifies and sinks after about 25 seconds. This process was repeated to obtain a sufficient number of spheres (Figure 1). All the spheres were finally packed into a 1.8 ml cryovial and stored in liquid nitrogen. | ||
Device | SpermVD | Warmed at room temperature, spermatozoa were located in the spermVD droplet, transferred to the collection droplet and used for ICSI. | [15] |
Medium | Quinn’s Advantage™ Sperm-freezing medium | ||
Procedure | Spermatozoa were transferred from the collection drop to a 0.8-1 μl droplet in the spermVD, and placed the spermVD inside a cryovial, plunged into liquid nitrogen (Figure 2). |
Human spermatozoa vitrification and warming procedure.
Vitrification with highly concentrated, permeable cryoprotectants is not suitable for spermatozoa as spermatozoa are osmotically sensitive. Sperm vitrification media is isomolar between 300 and 396 mOsm/L., which can be maintained by non-permeable cryoprotectants or a combination. The most commonly used permeable cryoprotectants include DMSO, glycerol, glycol, and ethylene. Non-permeable cryoprotectants include albumins, dextran, and egg yolk. Isachenko et al. developed cryoprotectant-free vitrification with capillaries method showing higher motility and integrity rates of cytoplasmic and acrosome membranes, and less cryo-injury in human sperm vitrification [2]. They used 52 human swim-up prepared ejaculated samples for vitrification without any permeable cryoprotectants. Some studies reported successful sperm vitrification in straws and cryoloop droplets for small volumes [2]. Azipurua et al. compared a permeable cryoprotectant-free vitrification protocol to the slow freezing method using 18 normal sperm samples and found that improved recovery rates of good quality sperm and better maintenance of sperm quality were generated in the vitrification group compared to the slow-freezing group [16]. Moreover, they demonstrated that vitrification with the cryoprotectant free method produced a higher percentage of spermatozoa, better preservation of acrosomes, and lower DNA fragmentation compared to the slow freezing method [16]. Additionally, they used alpha-tubulin immunochemistry to identify the similar labeling pattern of the sperm skeleton in the tail as fresh sperm, but different from post-thaw sperm from the slow freezing [16]. However, Agha-Rahimi et al. found there was no major difference in post-thaw motility, DNA fragmentation, or hyaluronan-binding potential with or without cryoprotectant for normospermia samples [17].
Regarding nonpermeable cryoprotectants, sucrose (0.25 M final concentration) and serum dextran supplement in a final concentration of 0.1% are generally used for sperm vitrification base medium. Some modifications have been made to the composition of the vitrification medium, for instance, Butylhydroxytoluene (BHT), a synthetic analog of vitamin E, was used as an antioxidant to improve the cryoprotective effects on human spermatozoa [18]. After warming, higher progressive sperm motility, DNA integrity, and lower reactive oxygen species were observed in the vitrification medium supplemented with BHT. The proposed mechanism of BHT is increasing the fluidity of the cell membrane via incorporation into the membrane [18]. Another study found that post-warming sperm motility using 0.1 mol/L trehalose (69%) was higher than that of used sucrose (0.25 M, 58%) with healthy volunteer semen samples [14]. Similar results were found at 6 and 12 h post-thaw. Furthermore, 0.1 mol/L trehalose improved membrane integrity at 0 h post-thaw. No significant improvements were found at 6 and 12 h in terms of membrane integrity [14]. According to these results, the use of trehalose increases tolerance to hypertonic and hypotonic conditions, preventing cell lysis and death during the vitrification and warming process. Additionally, the study demonstrated that post-thaw spermatozoa maintained at room temperature better than maintained at 37°C up to 4 h in terms of viability and mitochondrial membrane potential [14]. Zhou, D et al. developed a modified vitrification method which has a relatively better recovery rate (65.8%) and improved preservation of several sperm quality parameters compared with slow freezing (Figure 1). They used trehalose (0.5 mol/L) glycine (100 mol/L) and human serum albumin (1% w/v) as cryoprotectants to vitrify 28 semen samples from healthy participants [13].
Illustration of the vitrification process and device by Zhou, D et al. [
Collectively, some might perform better than others depending on specific situations/concentrations in terms of cryoprotectants. Further research is needed to investigate the optimal permeable and non-permeable cryoprotectants.
The vitrification process is based on an extremely high cooling rate that prevents ice crystal formation. A semen sample can be processed by swim-up and loading in straws or cryoloops, and then rapidly cooled by direct contact with liquid nitrogen (−196°C). After loading, the straws or cryoloops are put into the precooked aluminum blocks for long storage in liquid nitrogen or vapor phase in a liquid nitrogen tank (−180°C). Zhou, D et al. tested different combinations of carriers, including cryoleaf (Medicult, Jyllinge, Denmark), cryoloop (Hampton Research, Orange, CA, USA), and straw (Cryo Bio System, Paris, France). The highest freeze rate (about 10,000°C per min) is achieved by the cryoleaf and cryoloop system, however, they also exhibit the lowest freezing efficiencies (Figure 1) [13]. Berkovitz et al. tested a novel vitrification device spermVD and found it is an efficient and simple carrier method for freezing a small number of spermatozoa in low-volume droplets that significantly reduces post-thaw search time from hours to minutes, allowing a 96% recovery rate and leading to successful use of sperm for fertilization (Figure 2) [15]. The target populations are patients with a small number of spermatozoa, such as azoospermia patients, who have undergone a TESE/micro TESE procedure or severe oligozoospermia patients.
Sperm VD: An innovative and efficient medical device for cryopreservation of small numbers of spermatozoa [
Besides the high-speed freezing, the warming speed should also be high allowing the water inside spermatozoa to pass from a glassy state to liquid without ice crystal formation. Mansilla et al. tested different warming temperatures and found the progressive motility in sperm samples warmed at 42°C (65%) was higher than at 38°C (26%) and 40°C (57%) and plasma membrane function was better preserved at 42°C [19]. Pabon et al. warmed vitrified spermatozoa micro pills (5-10 μl each) in 500 μl prewarmed medium and maintained them at 44°C for 5 seconds and decent post-thaw motility and mitochondrial activity were observed [6]. Zhou D et al. warmed the sample by submerging the spheres in 5 ml G-IVF Plus medium pre-warmed to 37°C accompanied by gentle agitation for 5 min. Post-thaw sperm achieves a statistically significantly higher recovery rate, motility, morphology, and curve line velocity than slow freezing (p < 0.05) [13]. Furthermore, a lower rate of DNA fragmentation and better acrosome protection were observed in the spermatozoa after vitrification than slow freezing (p < 0.05) [13]. Schulz et al. found that 42°C was the optimal temperature to preserve the sperm parameters, including motility and membrane integrity in the warming process [1]. Collectively, the warming process is flexible in terms of temperature.
Cryopreservation of spermatozoa is the standard of care for fertility preservation in patients who undergo chemotherapy or radiotherapy. There are other reasons why a couple or individual patient needs to cryopreserve the spermatozoa, for instance, before vasectomy or in the case of a traveling husband. The conventional cryopreservation (slow freezing) protocol is standardized and widely used in clinical practice. The spermatozoa being vitrified with non-permeable cryoprotectants reduce the possibility of water inside the cell, allowing storage at lower temperatures. This technique is limited as only small volumes with small numbers of spermatozoa can be cryopreserved. The possibility that vitrified sperm preserve their function at temperature of −80°C could simplify storage, optimizing the space and time as well as the operator’s safety [3]. Lyophilization of spermatozoa is another method that requires additional investigation and validation [20]. Since the lyophilized spermatozoa are immobile, they can only be used in intracytoplasmic sperm injection (ICSI). Therefore, further research needs to be conducted on the optimization, safety, and health of the offspring.
Exposing the semen samples directly to liquid nitrogen increases the risk of contamination. A large variety of bacterial, viral, and fungal species have been found in liquid nitrogen [21]. Unsterilized commercial liquid nitrogen could cause transmission and propagation of diseases. On the other hand, the survival of cryogenic pathogens in liquid nitrogen creates the possibility of cross-contamination between stored contaminated semen samples and liquid nitrogen. Bacteria have a higher tolerance than fungi to freezing. Piasecka–Serafin reported bacteria contamination from infected semen samples to sterile liquid nitrogen and then other sterile semen pellets [22]. Within only 2 h of cryo-storage, about 94% of the sterile samples were contaminated with
The basic procedure to avoid contamination is to store contaminated or infected semen samples separately in quarantine to minimize the risk of cross-contamination. Sterilizing the air used to create a small amount of liquid nitrogen by using the air filter with 0.22 μm polytetrafluoroethylene efficiently retained
Another basic rule to control contamination is to avoid direct contact with liquid nitrogen. Using liquid nitrogen vapor, instead of liquid nitrogen itself, to store human semen samples can lower the risk of cross-contamination. Ultraviolet (UV) light could also be a possible way to reduce the contamination risk of vitrified sperm samples [24]. Treating a small volume of liquid nitrogen with 8000 us/cm2 UV light could kill the hepatitis B virus, while 330,000 us/cm2 destroyed the fungus Aspergillus niger [24]. Most viruses can be deactivated by UV light at a dose of 200,000 uw/cm2. But it has been reported that the Zika virus may have higher resistance to UV light [25]. The UV light can also possibly induce genetic aberrations in stored spermatozoa. A simple solution is to sterilize liquid nitrogen with UV light before sperm storage. Another concern is the generation of ozone by UV light, which could cause damage to the buffer system in which the sperm samples are stored. However, the formation of ozone from UV light is insignificant as the liquid quid is free from oxygen.
Although there is no way to completely eliminate all the potential risks of cross-contamination in sperm vitrification, it is possible to control the contamination risk of vitrification to the level of slow freezing.
In the past decades, slow freezing of human sperm is still the main method used for sperm cryopreservation. However, vitrification provides a simpler, faster, more cost-effective alternative to conventional methods. Major concerns of the vitrification are the size of the sample and cross contamination with open devices. Optimization of the vitrification medium, sample size, and devices are a promising option. Due to different characteristics of spermatozoa species, including normospermia, oligospermia, azoospermia, testicular sperm aspiration, and testicular sperm extraction samples with different parameters, there is no universal vitrification method to serve different cryopreservation purposes at human clinics. Specific sperm vitrification methods should be individually designed to reach the optimal results depending on the personalized purpose at clinics. Future research in human sperm vitrification should include validation of the vitrification methods and whether the vitrification of sperm can improve clinical ART outcomes.
I am grateful to Mr. John Dong’s help with proofreading and grammatical corrections.
The authors declare no conflict of interest.
assisted reproductive technology dimethyl sulfoxide intracytoplasmic sperm injection ultraviolet butylhydroxytoluene food and drug administration
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Its major nutritional limitation has been the low protein content and poor protein quality, which necessitates the use of expensive high‐protein supplements or synthetic amino acids such as lysine in diets containing large proportion of maize. Therefore, extensive research has been conducted by maize breeders on the world maize germplasms collection with the aim of improving its nutritive value, particularly protein quality for monogastric animals. This chapter assesses the genetic upgrading of the nutritional quality of maize protein that culminated in the development of a new class of maize known as “Quality Protein Maize (QPM)”. Various studies on the nutritionally improved maize for poultry as well as future challenges confronting maize utilisation in poultry production are highlighted.",book:{id:"5315",slug:"poultry-science",title:"Poultry Science",fullTitle:"Poultry Science"},signatures:"Herbert K. Dei",authors:[{id:"28844",title:"Prof.",name:"Herbert Kwabla",middleName:"Kwabla",surname:"Dei",slug:"herbert-kwabla-dei",fullName:"Herbert Kwabla Dei"}]},{id:"61570",title:"Adenoviruses and Their Diversity in Poultry",slug:"adenoviruses-and-their-diversity-in-poultry",totalDownloads:1804,totalCrossrefCites:2,totalDimensionsCites:4,abstract:"An investigation into the aetiology of fowl adenovirus strains and their distribution worldwide in populations of poultry flocks industry has been conducted. Pathogenic role of the viruses is not always clear. They can cause latent infection or several diseases and are the reason of economic losses in poultry flock industry. Ubiquity of adenovirus strains was commonly described, and stand-alone pathogenicity for a long time has been disputed. A globally emerging trend of adenoviruses and adenovirus-associated diseases has been increasing from year to year in all over the world. Mainly, type FAdV-4 is responsible for hydropericardium hepatitis syndrome (HP), type FAdV-1 for gizzard erosion and ulceration (GEU), and types FAdV-2, 8a, 8b, and 11 seem to be responsible for inclusion body hepatitis (IBH). Defining the spreading of the avian adenovirus strains in different types of fowl profile production, recognising their property and determining their types and molecular characterisation are very important from the epidemiological point of view and are considered as excellent basis for vaccine development and gene therapy implementation. This chapter provides a comprehensive review of FAdVs, including their epidemiology, pathogenesis, diagnostic, detection, and molecular characterisation. This comprehensive review is needed to better understand the latest progress in study of the viruses and prospects regarding disease control and implementation of gene therapy.",book:{id:"6623",slug:"application-of-genetics-and-genomics-in-poultry-science",title:"Application of Genetics and Genomics in Poultry Science",fullTitle:"Application of Genetics and Genomics in Poultry Science"},signatures:"Jowita Samanta Niczyporuk",authors:[{id:"212649",title:"Dr.",name:"Jowita Samanta",middleName:null,surname:"Niczyporuk",slug:"jowita-samanta-niczyporuk",fullName:"Jowita Samanta Niczyporuk"}]},{id:"65864",title:"Poultry Housing and Management",slug:"poultry-housing-and-management",totalDownloads:3238,totalCrossrefCites:5,totalDimensionsCites:11,abstract:"Majority of the people in the poorest regions of the tropics rely on poultry production as their major source of protein supply. However, poultry production is hindered by the harsh environmental conditions in this regions therefore, reducing the daily supply of protein. It is believed that understanding heat stress in birds by paying detail attention to the sources of heat generation in a poultry house can help manage the heat stress situation in this region. This text reviews the internal climatic conditions of the poultry houses, how the birds respond to them, and their implications for heat management in poultry production. Thus, it provides pertinent information for guidance on parameters for open poultry houses architectural design that ensures optimum climatic conditions that will alleviate heat stress problem in poultry production in hot and humid climate.",book:{id:"8470",slug:"poultry-an-advanced-learning",title:"Poultry",fullTitle:"Poultry - An Advanced Learning"},signatures:"Ayodeji Oloyo and Adedamola Ojerinde",authors:[{id:"273409",title:"Mr.",name:"Ayodeji",middleName:null,surname:"Oloyo",slug:"ayodeji-oloyo",fullName:"Ayodeji Oloyo"},{id:"274920",title:"MSc.",name:"Adedamola",middleName:null,surname:"Ojerinde",slug:"adedamola-ojerinde",fullName:"Adedamola Ojerinde"}]},{id:"61583",title:"Domestication and Welfare in Farmed Fish",slug:"domestication-and-welfare-in-farmed-fish",totalDownloads:1690,totalCrossrefCites:4,totalDimensionsCites:16,abstract:"The domestication of fish species is still in its early stages when compared to terrestrial animals. The effects of domestication on welfare of farmed fishes are complex to study because fish differ from livestock in genetics, physiology and behaviour, and experience different sensory worlds. Consequently, empathy with fish and understanding of their needs becomes more problematic than with land animals. Additionally, the acknowledgement and study of mental dimensions of fish existence is very recent. We discuss that higher levels of domestication in fish do not necessarily correspond to better welfare because (1) artificial selection by the aquaculture industry is mostly focused on production-related traits such as growth, and this selection process may have unknown negative effects on welfare-related traits; (2) the number of fish species presently farmed (circa 300) is 10-fold higher than land animals, rendering the establishment of standard welfare guidelines extremely complicated; (3) the current paradigm of the Five Freedoms guiding welfare is out-dated and was designed for livestock; and (4) there are still severe knowledge gaps in the biology of farmed fishes, especially in welfare-related traits. The implementation of humane farming systems should integrate industry, science and ethics in an open dialogue in order to produce relevant results.",book:{id:"6053",slug:"animal-domestication",title:"Animal Domestication",fullTitle:"Animal Domestication"},signatures:"João L. 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He is on the editorial board of several international peer-reviewed journals and has published many papers. Additionally, he has participated in many international and national congresses, seminars, and workshops with oral and poster presentations. He is an active member of many local and international organizations.",institutionString:"İskenderun Technical University",institution:{name:"İskenderun Technical University",country:{name:"Turkey"}}},{id:"61139",title:"Dr.",name:"Sergey",middleName:null,surname:"Tkachev",slug:"sergey-tkachev",fullName:"Sergey Tkachev",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/61139/images/system/61139.png",biography:"Dr. Sergey Tkachev is a senior research scientist at the Institute of Fundamental Medicine and Biology, Kazan Federal University, Russia, and at the Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia. He received his Ph.D. in Molecular Biology with his thesis “Genetic variability of the tick-borne encephalitis virus in natural foci of Novosibirsk city and its suburbs.” His primary field is molecular virology with research emphasis on vector-borne viruses, especially tick-borne encephalitis virus, Kemerovo virus and Omsk hemorrhagic fever virus, rabies virus, molecular genetics, biology, and epidemiology of virus pathogens.",institutionString:"Russian Academy of Sciences",institution:{name:"Russian Academy of Sciences",country:{name:"Russia"}}},{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/310962/images/system/310962.jpg",biography:"Amlan K. Patra, FRSB, obtained a Ph.D. in Animal Nutrition from Indian Veterinary Research Institute, India, in 2002. 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In 1992, Dr. Babinszky obtained a Ph.D. in Animal Nutrition from the University of Wageningen. His main research areas are swine and poultry nutrition. He has authored more than 300 publications (papers, book chapters) and edited four books and fourteen international conference proceedings.",institutionString:"University of Debrecen",institution:{name:"University of Debrecen",country:{name:"Hungary"}}},{id:"201830",title:"Dr.",name:"Fernando",middleName:"Sanchez",surname:"Davila",slug:"fernando-davila",fullName:"Fernando Davila",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/201830/images/5017_n.jpg",biography:"I am a professor at UANL since 1988. My research lines are the development of reproductive techniques in small ruminants. We also conducted research on sexual and social behavior in males.\nI am Mexican and study my professional career as an engineer in agriculture and animal science at UANL. Then take a masters degree in science in Germany (Animal breeding). Take a doctorate in animal science at the UANL.",institutionString:null,institution:{name:"Universidad Autónoma de Nuevo León",country:{name:"Mexico"}}},{id:"309250",title:"Dr.",name:"Miguel",middleName:null,surname:"Quaresma",slug:"miguel-quaresma",fullName:"Miguel Quaresma",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/309250/images/9059_n.jpg",biography:"Miguel Nuno Pinheiro Quaresma was born on May 26, 1974 in Dili, Timor Island. He is married with two children: a boy and a girl, and he is a resident in Vila Real, Portugal. He graduated in Veterinary Medicine in August 1998 and obtained his Ph.D. degree in Veterinary Sciences -Clinical Area in February 2015, both from the University of Trás-os-Montes e Alto Douro. He is currently enrolled in the Alternative Residency of the European College of Animal Reproduction. He works as a Senior Clinician at the Veterinary Teaching Hospital of UTAD (HVUTAD) with a role in clinical activity in the area of livestock and equine species as well as to support teaching and research in related areas. He teaches as an Invited Professor in Reproduction Medicine I and II of the Master\\'s in Veterinary Medicine degree at UTAD. Currently, he holds the position of Chairman of the Portuguese Buiatrics Association. He is a member of the Consultive Group on Production Animals of the OMV. He has 19 publications in indexed international journals (ISIS), as well as over 60 publications and oral presentations in both Portuguese and international journals and congresses.",institutionString:"University of Trás-os-Montes and Alto Douro",institution:{name:"University of Trás-os-Montes and Alto Douro",country:{name:"Portugal"}}},{id:"38652",title:"Prof.",name:"Rita",middleName:null,surname:"Payan-Carreira",slug:"rita-payan-carreira",fullName:"Rita Payan-Carreira",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRiFPQA0/Profile_Picture_1614601496313",biography:"Rita Payan Carreira earned her Veterinary Degree from the Faculty of Veterinary Medicine in Lisbon, Portugal, in 1985. She obtained her Ph.D. in Veterinary Sciences from the University of Trás-os-Montes e Alto Douro, Portugal. After almost 32 years of teaching at the University of Trás-os-Montes and Alto Douro, she recently moved to the University of Évora, Department of Veterinary Medicine, where she teaches in the field of Animal Reproduction and Clinics. Her primary research areas include the molecular markers of the endometrial cycle and the embryo–maternal interaction, including oxidative stress and the reproductive physiology and disorders of sexual development, besides the molecular determinants of male and female fertility. She often supervises students preparing their master's or doctoral theses. She is also a frequent referee for various journals.",institutionString:null,institution:{name:"University of Évora",country:{name:"Portugal"}}},{id:"283019",title:"Dr.",name:"Oudessa",middleName:null,surname:"Kerro Dego",slug:"oudessa-kerro-dego",fullName:"Oudessa Kerro Dego",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/283019/images/system/283019.png",biography:"Dr. Kerro Dego is a veterinary microbiologist with training in veterinary medicine, microbiology, and anatomic pathology. Dr. Kerro Dego is an assistant professor of dairy health in the department of animal science, the University of Tennessee, Institute of Agriculture, Knoxville, Tennessee. He received his D.V.M. (1997), M.S. (2002), and Ph.D. (2008) degrees in Veterinary Medicine, Animal Pathology and Veterinary Microbiology from College of Veterinary Medicine, Addis Ababa University, Ethiopia; College of Veterinary Medicine, Utrecht University, the Netherlands and Western College of Veterinary Medicine, University of Saskatchewan, Canada respectively. He did his Postdoctoral training in microbial pathogenesis (2009 - 2015) in the Department of Animal Science, the University of Tennessee, Institute of Agriculture, Knoxville, Tennessee. Dr. Kerro Dego’s research focuses on the prevention and control of infectious diseases of farm animals, particularly mastitis, improving dairy food safety, and mitigation of antimicrobial resistance. Dr. Kerro Dego has extensive experience in studying the pathogenesis of bacterial infections, identification of virulence factors, and vaccine development and efficacy testing against major bacterial mastitis pathogens. Dr. Kerro Dego conducted numerous controlled experimental and field vaccine efficacy studies, vaccination, and evaluation of immunological responses in several species of animals, including rodents (mice) and large animals (bovine and ovine).",institutionString:"University of Tennessee at Knoxville",institution:{name:"University of Tennessee at Knoxville",country:{name:"United States of America"}}},{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón Poggi",slug:"juan-carlos-gardon-poggi",fullName:"Juan Carlos Gardón Poggi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",biography:"Juan Carlos Gardón Poggi received University degree from the Faculty of Agrarian Science in Argentina, in 1983. Also he received Masters Degree and PhD from Córdoba University, Spain. He is currently a Professor at the Catholic University of Valencia San Vicente Mártir, at the Department of Medicine and Animal Surgery. He teaches diverse courses in the field of Animal Reproduction and he is the Director of the Veterinary Farm. He also participates in academic postgraduate activities at the Veterinary Faculty of Murcia University, Spain. His research areas include animal physiology, physiology and biotechnology of reproduction either in males or females, the study of gametes under in vitro conditions and the use of ultrasound as a complement to physiological studies and development of applied biotechnologies. Routinely, he supervises students preparing their doctoral, master thesis or final degree projects.",institutionString:null,institution:{name:"Valencia Catholic University Saint Vincent Martyr",country:{name:"Spain"}}},{id:"309529",title:"Dr.",name:"Albert",middleName:null,surname:"Rizvanov",slug:"albert-rizvanov",fullName:"Albert Rizvanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/309529/images/9189_n.jpg",biography:'Albert A. Rizvanov is a Professor and Director of the Center for Precision and Regenerative Medicine at the Institute of Fundamental Medicine and Biology, Kazan Federal University (KFU), Russia. He is the Head of the Center of Excellence “Regenerative Medicine” and Vice-Director of Strategic Academic Unit \\"Translational 7P Medicine\\". Albert completed his Ph.D. at the University of Nevada, Reno, USA and Dr.Sci. at KFU. He is a corresponding member of the Tatarstan Academy of Sciences, Russian Federation. Albert is an author of more than 300 peer-reviewed journal articles and 22 patents. He has supervised 11 Ph.D. and 2 Dr.Sci. dissertations. Albert is the Head of the Dissertation Committee on Biochemistry, Microbiology, and Genetics at KFU.\nORCID https://orcid.org/0000-0002-9427-5739\nWebsite https://kpfu.ru/Albert.Rizvanov?p_lang=2',institutionString:"Kazan Federal University",institution:{name:"Kazan Federal University",country:{name:"Russia"}}},{id:"210551",title:"Dr.",name:"Arbab",middleName:null,surname:"Sikandar",slug:"arbab-sikandar",fullName:"Arbab Sikandar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210551/images/system/210551.jpg",biography:"Dr. Arbab Sikandar, PhD, M. Phil, DVM was born on April 05, 1981. He is currently working at the College of Veterinary & Animal Sciences as an Assistant Professor. He previously worked as a lecturer at the same University. \nHe is a Member/Secretory of Ethics committee (No. CVAS-9377 dated 18-04-18), Member of the QEC committee CVAS, Jhang (Regr/Gen/69/873, dated 26-10-2017), Member, Board of studies of Department of Basic Sciences (No. CVAS. 2851 Dated. 12-04-13, and No. CVAS, 9024 dated 20/11/17), Member of Academic Committee, CVAS, Jhang (No. CVAS/2004, Dated, 25-08-12), Member of the technical committee (No. CVAS/ 4085, dated 20,03, 2010 till 2016).\n\nDr. Arbab Sikandar contributed in five days hands-on-training on Histopathology at the Department of Pathology, UVAS from 12-16 June 2017. He received a Certificate of appreciation for contributions for Popularization of Science and Technology in the Society on 17-11-15. He was the resource person in the lecture series- ‘scientific writing’ at the Department of Anatomy and Histology, UVAS, Lahore on 29th October 2015. He won a full fellowship as a principal candidate for the year 2015 in the field of Agriculture, EICA, Egypt with ref. to the Notification No. 12(11) ACS/Egypt/2014 from 10 July 2015 to 25th September 2015.; he received a grant of Rs. 55000/- as research incentives from Director, Advanced Studies and Research, UVAS, Lahore upon publications of research papers in IF Journals (DR/215, dated 19-5-2014.. He obtained his PhD by winning a HEC Pakistan indigenous Scholarship, ‘Ph.D. fellowship for 5000 scholars – Phase II’ (2av1-147), 17-6/HEC/HRD/IS-II/12, November 15, 2012. \n\nDr. Sikandar is a member of numerous societies: Registered Veterinary Medical Practitioner (life member) and Registered Veterinary Medical Faculty of Pakistan Veterinary Medical Council. The Registration code of PVMC is RVMP/4298 and RVMF/ 0102.; Life member of the University of Veterinary and Animal Sciences, Lahore, Alumni Association with S# 664, dated: 6-4-12. ; Member 'Vets Care Organization Pakistan” with Reference No. VCO-605-149, dated 05-04-06. :Member 'Vet Crescent” (Society of Animal Health and Production), UVAS, Lahore.",institutionString:"University of Veterinary & Animal Science",institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}},{id:"311663",title:"Dr.",name:"Prasanna",middleName:null,surname:"Pal",slug:"prasanna-pal",fullName:"Prasanna Pal",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311663/images/13261_n.jpg",biography:null,institutionString:null,institution:{name:"National Dairy Research Institute",country:{name:"India"}}},{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",biography:"Catrin Rutland is an Associate Professor of Anatomy and Developmental Genetics at the University of Nottingham, UK. She obtained a BSc from the University of Derby, England, a master’s degree from Technische Universität München, Germany, and a Ph.D. from the University of Nottingham. She undertook a post-doctoral research fellowship in the School of Medicine before accepting tenure in Veterinary Medicine and Science. Dr. Rutland also obtained an MMedSci (Medical Education) and a Postgraduate Certificate in Higher Education (PGCHE). She is the author of more than sixty peer-reviewed journal articles, twelve books/book chapters, and more than 100 research abstracts in cardiovascular biology and oncology. She is a board member of the European Association of Veterinary Anatomists, Fellow of the Anatomical Society, and Senior Fellow of the Higher Education Academy. Dr. Rutland has also written popular science books for the public. https://orcid.org/0000-0002-2009-4898. www.nottingham.ac.uk/vet/people/catrin.rutland",institutionString:null,institution:{name:"University of Nottingham",country:{name:"United Kingdom"}}},{id:"283315",title:"Prof.",name:"Samir",middleName:null,surname:"El-Gendy",slug:"samir-el-gendy",fullName:"Samir El-Gendy",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRduYQAS/Profile_Picture_1606215849748",biography:"Samir El-Gendy is a Professor of anatomy and embryology at the faculty of veterinary medicine, Alexandria University, Egypt. Samir obtained his PhD in veterinary science in 2007 from the faculty of veterinary medicine, Alexandria University and has been a professor since 2017. Samir is an author on 24 articles at Scopus and 12 articles within local journals and 2 books/book chapters. His research focuses on applied anatomy, imaging techniques and computed tomography. Samir worked as a member of different local projects on E-learning and he is a board member of the African Association of Veterinary Anatomists and of anatomy societies and as an associated author at local and international journals. Orcid: https://orcid.org/0000-0002-6180-389X",institutionString:null,institution:{name:"Alexandria University",country:{name:"Egypt"}}},{id:"246149",title:"Dr.",name:"Valentina",middleName:null,surname:"Kubale",slug:"valentina-kubale",fullName:"Valentina Kubale",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246149/images/system/246149.jpg",biography:"Valentina Kubale is Associate Professor of Veterinary Medicine at the Veterinary Faculty, University of Ljubljana, Slovenia. Since graduating from the Veterinary faculty she obtained her PhD in 2007, performed collaboration with the Department of Pharmacology, University of Copenhagen, Denmark. She continued as a post-doctoral fellow at the University of Copenhagen with a Lundbeck foundation fellowship. She is the editor of three books and author/coauthor of 23 articles in peer-reviewed scientific journals, 16 book chapters, and 68 communications at scientific congresses. Since 2008 she has been the Editor Assistant for the Slovenian Veterinary Research journal. She is a member of Slovenian Biochemical Society, The Endocrine Society, European Association of Veterinary Anatomists and Society for Laboratory Animals, where she is board member.",institutionString:"University of Ljubljana",institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"258334",title:"Dr.",name:"Carlos Eduardo",middleName:null,surname:"Fonseca-Alves",slug:"carlos-eduardo-fonseca-alves",fullName:"Carlos Eduardo Fonseca-Alves",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/258334/images/system/258334.jpg",biography:"Dr. Fonseca-Alves earned his DVM from Federal University of Goias – UFG in 2008. He completed an internship in small animal internal medicine at UPIS university in 2011, earned his MSc in 2013 and PhD in 2015 both in Veterinary Medicine at Sao Paulo State University – UNESP. Dr. Fonseca-Alves currently serves as an Assistant Professor at Paulista University – UNIP teaching small animal internal medicine.",institutionString:null,institution:{name:"Universidade Paulista",country:{name:"Brazil"}}},{id:"245306",title:"Dr.",name:"María Luz",middleName:null,surname:"Garcia Pardo",slug:"maria-luz-garcia-pardo",fullName:"María Luz Garcia Pardo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/245306/images/system/245306.png",biography:"María de la Luz García Pardo is an agricultural engineer from Universitat Politècnica de València, Spain. She has a Ph.D. in Animal Genetics. Currently, she is a lecturer at the Agrofood Technology Department of Miguel Hernández University, Spain. Her research is focused on genetics and reproduction in rabbits. The major goal of her research is the genetics of litter size through novel methods such as selection by the environmental sensibility of litter size, with forays into the field of animal welfare by analysing the impact on the susceptibility to diseases and stress of the does. Details of her publications can be found at https://orcid.org/0000-0001-9504-8290.",institutionString:null,institution:{name:"Miguel Hernandez University",country:{name:"Spain"}}},{id:"350704",title:"M.Sc.",name:"Camila",middleName:"Silva Costa",surname:"Ferreira",slug:"camila-ferreira",fullName:"Camila Ferreira",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/350704/images/17280_n.jpg",biography:"Graduated in Veterinary Medicine at the Fluminense Federal University, specialist in Equine Reproduction at the Brazilian Veterinary Institute (IBVET) and Master in Clinical Veterinary Medicine and Animal Reproduction at the Fluminense Federal University. She has experience in analyzing zootechnical indices in dairy cattle and organizing events related to Veterinary Medicine through extension grants. I have experience in the field of diagnostic imaging and animal reproduction in veterinary medicine through monitoring and scientific initiation scholarships. I worked at the Equus Central Reproduction Equine located in Santo Antônio de Jesus – BA in the 2016/2017 breeding season. I am currently a doctoral student with a scholarship from CAPES of the Postgraduate Program in Veterinary Medicine (Pathology and Clinical Sciences) at the Federal Rural University of Rio de Janeiro (UFRRJ) with a research project with an emphasis on equine endometritis.",institutionString:null,institution:null},{id:"41319",title:"Prof.",name:"Lung-Kwang",middleName:null,surname:"Pan",slug:"lung-kwang-pan",fullName:"Lung-Kwang Pan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41319/images/84_n.jpg",biography:null,institutionString:null,institution:null},{id:"125292",title:"Dr.",name:"Katy",middleName:null,surname:"Satué Ambrojo",slug:"katy-satue-ambrojo",fullName:"Katy Satué Ambrojo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/125292/images/system/125292.jpeg",biography:"Katy Satué Ambrojo received her Veterinary Medicine degree, Master degree in Equine Technology and doctorate in Veterinary Medicine from the Faculty of Veterinary, CEU-Cardenal Herrera University in Valencia, Spain.Dr. Satué is accredited as a Private University Doctor Professor, Doctor Assistant, and Contracted Doctor by AVAP (Agència Valenciana d'Avaluació i Prospectiva) and currently, as a full professor by ANECA (since January 2022). To date, Katy has taught 22 years in the Department of Animal Medicine and Surgery at the CEU-Cardenal Herrera University in undergraduate courses in Veterinary Medicine (General Pathology, integrated into the Applied Basis of Veterinary Medicine module of the 2nd year, Clinical Equine I of 3rd year, and Equine Clinic II of 4th year). Dr. Satué research activity is in the field of Endocrinology, Hematology, Biochemistry, and Immunology in the Spanish Purebred mare. She has directed 5 Doctoral Theses and 5 Diplomas of Advanced Studies, and participated in 11 research projects as a collaborating researcher. She has written 2 books and 14 book chapters in international publishers related to the area, and 68 scientific publications in international journals. Dr. Satué has attended 63 congresses, participating with 132 communications in international congresses and 19 in national congresses related to the area. Dr. Satué is a scientific reviewer for various prestigious international journals such as Animals, American Journal of Obstetrics and Gynecology, Veterinary Clinical Pathology, Journal of Equine Veterinary Science, Reproduction in Domestic Animals, Research Veterinary Science, Brazilian Journal of Medical and Biological Research, Livestock Production Science and Theriogenology, among others. Since 2014 she has been responsible for the Clinical Analysis Laboratory of the CEU-Cardenal Herrera University Veterinary Clinical Hospital.",institutionString:null,institution:null},{id:"201721",title:"Dr.",name:"Beatrice",middleName:null,surname:"Funiciello",slug:"beatrice-funiciello",fullName:"Beatrice Funiciello",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/201721/images/11089_n.jpg",biography:"Graduated from the University of Milan in 2011, my post-graduate education included CertAVP modules mainly on equines (dermatology and internal medicine) and a few on small animal (dermatology and anaesthesia) at the University of Liverpool. After a general CertAVP (2015) I gained the designated Certificate in Veterinary Dermatology (2017) after taking the synoptic examination and then applied for the RCVS ADvanced Practitioner status. After that, I completed the Postgraduate Diploma in Veterinary Professional Studies at the University of Liverpool (2018). My main area of work is cross-species veterinary dermatology.",institutionString:null,institution:null},{id:"291226",title:"Dr.",name:"Monica",middleName:null,surname:"Cassel",slug:"monica-cassel",fullName:"Monica Cassel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/291226/images/8232_n.jpg",biography:'Degree in Biological Sciences at the Federal University of Mato Grosso with scholarship for Scientific Initiation by FAPEMAT (2008/1) and CNPq (2008/2-2009/2): Project \\"Histological evidence of reproductive activity in lizards of the Manso region, Chapada dos Guimarães, Mato Grosso, Brazil\\". Master\\\'s degree in Ecology and Biodiversity Conservation at Federal University of Mato Grosso with a scholarship by CAPES/REUNI program: Project \\"Reproductive biology of Melanorivulus punctatus\\". PhD\\\'s degree in Science (Cell and Tissue Biology Area) \n at University of Sao Paulo with scholarship granted by FAPESP; Project \\"Development of morphofunctional changes in ovary of Astyanax altiparanae Garutti & Britski, 2000 (Teleostei, Characidae)\\". She has experience in Reproduction of vertebrates and Morphology, with emphasis in Cellular Biology and Histology. She is currently a teacher in the medium / technical level courses at IFMT-Alta Floresta, as well as in the Bachelor\\\'s degree in Animal Science and in the Bachelor\\\'s degree in Business.',institutionString:null,institution:null},{id:"442807",title:"Dr.",name:"Busani",middleName:null,surname:"Moyo",slug:"busani-moyo",fullName:"Busani Moyo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Gwanda State University",country:{name:"Zimbabwe"}}},{id:"439435",title:"Dr.",name:"Feda S.",middleName:null,surname:"Aljaser",slug:"feda-s.-aljaser",fullName:"Feda S. 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The applications of this research cover many related fields, such as biotechnology and medicine, where, for example, Bioinformatics contributes to faster drug design, DNA analysis in forensics, and DNA sequence analysis in the field of personalized medicine. Personalized medicine is a type of medical care in which treatment is customized individually for each patient. Personalized medicine enables more effective therapy, reduces the costs of therapy and clinical trials, and also minimizes the risk of side effects. Nevertheless, advances in personalized medicine would not have been possible without bioinformatics, which can analyze the human genome and other vast amounts of biomedical data, especially in genetics. The rapid growth of information technology enabled the development of new tools to decode human genomes, large-scale studies of genetic variations and medical informatics. The considerable development of technology, including the computing power of computers, is also conducive to the development of bioinformatics, including personalized medicine. In an era of rapidly growing data volumes and ever lower costs of generating, storing and computing data, personalized medicine holds great promises. Modern computational methods used as bioinformatics tools can integrate multi-scale, multi-modal and longitudinal patient data to create even more effective and safer therapy and disease prevention methods. Main aspects of the topic are: Applying bioinformatics in drug discovery and development; Bioinformatics in clinical diagnostics (genetic variants that act as markers for a condition or a disease); Blockchain and Artificial Intelligence/Machine Learning in personalized medicine; Customize disease-prevention strategies in personalized medicine; Big data analysis in personalized medicine; Translating stratification algorithms into clinical practice of personalized medicine.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11403,editor:{id:"351533",title:"Dr.",name:"Slawomir",middleName:null,surname:"Wilczynski",slug:"slawomir-wilczynski",fullName:"Slawomir Wilczynski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035U1loQAC/Profile_Picture_1630074514792",biography:"Professor Sławomir Wilczyński, Head of the Chair of Department of Basic Biomedical Sciences, Faculty of Pharmaceutical Sciences, Medical University of Silesia in Katowice, Poland. 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Editor-in-chief of the journal in the field of aesthetic medicine and dermatology - Aesthetica.",institutionString:null,institution:{name:"Medical University of Silesia",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null,series:{id:"7",title:"Biomedical Engineering",doi:"10.5772/intechopen.71985",issn:"2631-5343"},editorialBoard:[{id:"5886",title:"Dr.",name:"Alexandros",middleName:"T.",surname:"Tzallas",slug:"alexandros-tzallas",fullName:"Alexandros Tzallas",profilePictureURL:"https://mts.intechopen.com/storage/users/5886/images/system/5886.png",institutionString:"University of Ioannina, Greece & Imperial College London",institution:{name:"University of Ioannina",institutionURL:null,country:{name:"Greece"}}},{id:"257388",title:"Distinguished Prof.",name:"Lulu",middleName:null,surname:"Wang",slug:"lulu-wang",fullName:"Lulu Wang",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRX6kQAG/Profile_Picture_1630329584194",institutionString:"Shenzhen Technology University",institution:{name:"Shenzhen Technology University",institutionURL:null,country:{name:"China"}}},{id:"225387",title:"Prof.",name:"Reda R.",middleName:"R.",surname:"Gharieb",slug:"reda-r.-gharieb",fullName:"Reda R. 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