We report the synthesis of six multifunctional cationic cholesteric liquid crystals polyesters functionalized with choline, amine, and amide groups to obtain new chemical formulations involving macromolecular features with new properties added to those of precursor chiral cholesteric polyesters. They are designed as PTOBDME-choline [(C34H36O8)n─C5H13N]; PTOBEE-choline [(C26H20O8)n─C5H13N]; PTOBDME-ammonium [(C34H36O8)n─C5H13N]; PTOBEE-ammonium [(C26H20O8)n─C5H13N]; PTOBUME-amide (C33H33O9N)n; and PTOBEE-amide (C26H19O9N)n. Structural characterization is performed by NMR. Thermal behavior is studied by thermogravimetry (TG) and differential scanning calorimetry (DSC), showing all the polymers endothermic transition from crystal phase to liquid crystal mesophase. Chirality is determined by optical rotatory dispersion (ORD). The cationic cholesteric liquid crystal polymers described here have proved to act as nonviral vectors in gene therapy, transfecting DNA to the nucleus cell.
Part of the book: Liquid Crystals