The renin-angiotensin system (RAS) is a chief regulator of the cardiovascular system and body fluid homeostasis. Stem/progenitor cell therapy has pointed towards a novel tool for medical and therapeutic intervention. In addition to the physiological and pathological role of the RAS and its pharmacological inhibitors, the proliferation, differentiation in stem cells is mediated through various cell-signalling pathways. This book chapter reviews the new role of RAS components, distinct from other common roles by considering its regulating impact on the several signalling pathways involved in different body tissues, as well as in stem cell therapy.
Part of the book: Renin-Angiotensin System