To date, the genetic loci associated with disease and economic traits have been identified in livestock based on linkage analysis or genome-wide association studies. These analyses require the use of numerous genetic markers, of which microsatellites have been utilized most extensively because they allow for the easy genotyping of allelic variation at each locus using PCR. In the domestic goat (Capra hircus), microsatellite markers are powerful tools for various genetic studies, such as the estimation of intra- and interpopulation genetic diversity, linkage analyses of phenotypic traits, and marker-assisted selection of favorable phenotypes; however, the studies on goats are less extensive than those on other major livestock. The aim of this chapter is to summarize the currently available information on goat breeding using microsatellite markers. In particular, we use various studies, including our own recent work, to illustrate how these markers may be used to identify phenotypic traits.
Part of the book: Microsatellite Markers