\\n\\n
More than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\\n\\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\\n\\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\\n\\nAdditionally, each book published by IntechOpen contains original content and research findings.
\\n\\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\\n\\n\\n\\n
\\n"}]',published:!0,mainMedia:{caption:"IntechOpen Maintains",originalUrl:"/media/original/113"}},components:[{type:"htmlEditorComponent",content:'
Simba Information has released its Open Access Book Publishing 2020 - 2024 report and has again identified IntechOpen as the world’s largest Open Access book publisher by title count.
\n\nSimba Information is a leading provider for market intelligence and forecasts in the media and publishing industry. The report, published every year, provides an overview and financial outlook for the global professional e-book publishing market.
\n\nIntechOpen, De Gruyter, and Frontiers are the largest OA book publishers by title count, with IntechOpen coming in at first place with 5,101 OA books published, a good 1,782 titles ahead of the nearest competitor.
\n\nSince the first Open Access Book Publishing report published in 2016, IntechOpen has held the top stop each year.
\n\n\n\nMore than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\n\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\n\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\n\nAdditionally, each book published by IntechOpen contains original content and research findings.
\n\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\n\n\n\n
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"5067",leadTitle:null,fullTitle:"Insecticides Resistance",title:"Insecticides Resistance",subtitle:null,reviewType:"peer-reviewed",abstract:"This book contains 20 chapters, which are divided into 5 sections. Section 1 covers different aspects of insecticide resistance of selected economically important plant insect pests, whereas section 2 includes chapters about the importance, development and insecticide resistance management in controlling malaria vectors. Section 3 is dedicated to some general questions in insecticide resistance, while the main topic of section 4 is biochemical approaches of insecticide resistance mechanisms. Section 5 covers ecologically acceptable approaches for overcoming insecticide resistance, such are the use of mycoinsecticides, and understanding the role of some plant chemical compounds, which are important in interactions between plants, their pests and biological control agents.",isbn:"978-953-51-2258-6",printIsbn:null,pdfIsbn:"978-953-51-4208-9",doi:"10.5772/60478",price:139,priceEur:155,priceUsd:179,slug:"insecticides-resistance",numberOfPages:450,isOpenForSubmission:!1,isInWos:1,isInBkci:!0,hash:"e0c89a15887b47c513a572364c7d9336",bookSignature:"Stanislav Trdan",publishedDate:"March 2nd 2016",coverURL:"https://cdn.intechopen.com/books/images_new/5067.jpg",numberOfDownloads:40580,numberOfWosCitations:115,numberOfCrossrefCitations:70,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:145,numberOfDimensionsCitationsByBook:0,hasAltmetrics:0,numberOfTotalCitations:330,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 19th 2015",dateEndSecondStepPublish:"April 9th 2015",dateEndThirdStepPublish:"July 14th 2015",dateEndFourthStepPublish:"October 12th 2015",dateEndFifthStepPublish:"November 11th 2015",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,8",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"78285",title:"Prof.",name:"Stanislav",middleName:null,surname:"Trdan",slug:"stanislav-trdan",fullName:"Stanislav Trdan",profilePictureURL:"https://mts.intechopen.com/storage/users/78285/images/3405_n.jpg",biography:"Prof. Stanislav Trdan, head of the Chair of Phytomedicine, Agricultural Engineering, Crop Production, Pasture and Grassland Management (Dept. of Agronomy, Biotechnical Faculty, University of Ljubljana, Slovenia), obtained his BSc, MSc and PhD (agricultural entomology) from the University of Ljubljana. Since 2006, he has been the president of the Plant Protection Society of Slovenia; since 2008, he has been an associate professor of plant protection. He is a member of many international and national research societies. He has organised two international symposia and (co)organised four national conferences in the field of plant protection. He has attended almost 30 international and 20 national conferences, workshops and seminars. Until now, he was a leader of four national scientific projects and a member of many national and international project groups. Dr. Trdan has published more than 100 scientific papers, and he or the members of his research group have given approximately 90 presentations at symposia. He was the supervisor of four PhD theses, six MSc theses and approximately 70 undergraduate theses. He was a reviewer of more than 50 scientific papers from the field of agricultural entomology or plant protection. His fields of interest are agricultural entomology and zoology, integrated pest management, biological control and other alternatives for controlling plant pests and the efficacy of insecticides.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"3",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"University of Ljubljana",institutionURL:null,country:{name:"Slovenia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"318",title:"Pestology",slug:"animal-biology-pestology"}],chapters:[{id:"49828",title:"Resistance to neurotoxic insecticides in populations of the coffee leafminer Leucoptera coffeella",doi:"10.5772/61466",slug:"resistance-to-neurotoxic-insecticides-in-populations-of-the-coffee-leafminer-leucoptera-coffeella",totalDownloads:1682,totalCrossrefCites:3,totalDimensionsCites:4,hasAltmetrics:0,abstract:"Coffee leafminer Leucoptera coffeella is an important pest on coffee. The continued use of chemicals can result in loss of efficacy and selection of leafminer-resistant populations. We aimed to identify L. coffeella populations resistant to old and new neurotoxic insecticides in regions of Brazil. We collected seven populations of L. coffeella in Brazil. Low levels of resistance were observed for the insecticides chlorantraniliprole (1.02-3.23 times), abamectin (1.19-4.80 times), and deltamethrin (1.05-5.35 times). High resistance levels were observed for profenofos (65.3-522 times) and chlorpyrifos (4.53-18.63 times). We conclude that Brazilian L. coffeella populations showed greater resistance to organophosphate insecticides. Furthermore, resistance may be associated with the distance between the coffee-producing regions.",signatures:"Daianna P. Costa, Flávio L. Fernandes, Flávia M. Alves, Ézio M. da\nSilva and Liliane E. Visôtto",downloadPdfUrl:"/chapter/pdf-download/49828",previewPdfUrl:"/chapter/pdf-preview/49828",authors:[{id:"160619",title:"Dr.",name:"Flávio",surname:"Fernandes",slug:"flavio-fernandes",fullName:"Flávio Fernandes"}],corrections:null},{id:"49232",title:"Role of AChE in Colorado Potato Beetle (Leptinotarsa decemlineata Say) Resistance to Carbamates and Organophosphates",doi:"10.5772/61460",slug:"role-of-ache-in-colorado-potato-beetle-leptinotarsa-decemlineata-say-resistance-to-carbamates-and-or",totalDownloads:1911,totalCrossrefCites:4,totalDimensionsCites:5,hasAltmetrics:0,abstract:"Colorado potato beetle is one of the most important pests of potatoes and one of the most difficult insects to control. Over the years, none of the control techniques developed against this pest has provided long-term protection for potato crops. Worldwide, CPB is resistant to all major groups of insecticides, including organophosphates and carbamates. The target site of organophosphate (OP) and carbamate insecticides is the same; they inhibit the activity of AChE. The function of acetylcholinesterase (AChE) is degradation of acetylcholine (ACh - neurotransmitter) in the insect cholinergic synapses. Mutations in the AChE-encoding locus have been shown to confer target site insensitivity to organophosphate and carbamate insecticides, leading to modification of AChE (MACE). A range of other amino acid substitutions in AChE confer insecticide resistance, and these mutations typically reside near to or within the active site of the enzyme. Such AChE mutations, associated with insecticide resistance, mostly known as Ace in Drosophila, have also been observed in other species, including L. decemlineata. Based on bioassays and literature, modified/insensitive AChE confers two major patterns of resistance to OPs/carbamates. Pattern I resistance is characterized by significantly higher resistance ratios (RR) (much greater reduction in the sensitivity of AChE at the biochemical level) to carbamates than to organophosphate insecticides. Pattern II resistance is characterized by resistance ratios (and/or reductions in the sensitivity of AChE) that are approximately equivalent for both carbamates and OPs. There are also a few species for which an insensitive AChE has been reported and for which molecular data have been collected, but for which the resistance profiles for both OPs and carbamates have not been reported. For CPB, both patterns were registered.",signatures:"Miroslav Kostic, Sladjan Stankovic and Janja Kuzevski",downloadPdfUrl:"/chapter/pdf-download/49232",previewPdfUrl:"/chapter/pdf-preview/49232",authors:[{id:"176263",title:"Dr.",name:"Miroslav",surname:"Kostic",slug:"miroslav-kostic",fullName:"Miroslav Kostic"},{id:"176326",title:"Dr.",name:"Sladjan",surname:"Stankovic",slug:"sladjan-stankovic",fullName:"Sladjan Stankovic"},{id:"176333",title:"Dr.",name:"Janja",surname:"Kuzevski",slug:"janja-kuzevski",fullName:"Janja Kuzevski"}],corrections:null},{id:"49309",title:"Spirotetramat — An Alternative for the Control of Parasitic Sucking Insects and its Fate in the Environment",doi:"10.5772/61322",slug:"spirotetramat-an-alternative-for-the-control-of-parasitic-sucking-insects-and-its-fate-in-the-enviro",totalDownloads:3554,totalCrossrefCites:2,totalDimensionsCites:6,hasAltmetrics:0,abstract:"Spirotetramat is an insecticide derived from tetramic acid, a systemic material, for the control of sucking insects in their juvenile, immature stages, including aphids, scale insects, and whitefly. It produces growth inhibition of younger insects, reduces the ability of insects to reproduce, resulting in mortality. It acts to inhibit the biosynthesis of lipids and represents a new alternative for the control of problematic insects such as Planococcus ficus and Aphis gossypii. After a foliar application of spirotetramat, it enters the plant and transforms to its metabolite enol, along with the metabolite ketohydroxy, which are the two main products of degradation.",signatures:"Norma-Julieta Salazar-López, María-Lourdes Aldana-Madrid, María-\nIsabel Silveira-Gramont and José-Luis Aguiar",downloadPdfUrl:"/chapter/pdf-download/49309",previewPdfUrl:"/chapter/pdf-preview/49309",authors:[{id:"83125",title:"Dr.",name:"Maria Lourdes",surname:"Aldana Madrid",slug:"maria-lourdes-aldana-madrid",fullName:"Maria Lourdes Aldana Madrid"},{id:"84143",title:"Dr.",name:"Maria Isabel",surname:"Silveira",slug:"maria-isabel-silveira",fullName:"Maria Isabel Silveira"},{id:"176356",title:"MSc.",name:"Norma-Julieta",surname:"Salazar-Lopez",slug:"norma-julieta-salazar-lopez",fullName:"Norma-Julieta Salazar-Lopez"},{id:"176357",title:"MSc.",name:"José-Luis",surname:"Aguiar",slug:"jose-luis-aguiar",fullName:"José-Luis Aguiar"}],corrections:null},{id:"49332",title:"Management Practices for Insect Resistance in Bt Maize",doi:"10.5772/61653",slug:"management-practices-for-insect-resistance-in-bt-maize",totalDownloads:1667,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"The failure to reduce the population of a phytophagous species recognized as a key pest in a given situation usually occurs by not using the principles of Integrated Pest Management (IPM). The control of insect pests in agriculture has been done mainly through the application of chemical insecticides. However, chemical insecticides has lost effectiveness due to the selection of populations of resistant insects and cause adverse environmental effects. The main resistance management programs (IRM) strategy is the use of ‘high dose/refuge’, which involves the use of high dose of Bt protein in plants, promoting high mortality of heterozygotes associated with the planting of refuge, ie, a proportion of the crop in which it must be planted a non-Bt variety, allowing the survival of susceptible individuals. The emergence of Bt crops is an important step between the tactics available for pest control in various crops such as maize, canola, cotton and, in the near future, soybeans.",signatures:"Gleberson Guillen Piccinin, Alessandro Lucca Braccini, Andréia\nKazumi Suzukawa, Ricardo Shigueru Okumura, Claudete Rosa da\nSilva, Allan Klynger da Silva Lobato and Daiane de Cinque Mariano",downloadPdfUrl:"/chapter/pdf-download/49332",previewPdfUrl:"/chapter/pdf-preview/49332",authors:[{id:"21048",title:"Dr.",name:"Alessandro",surname:"Lucca Braccini",slug:"alessandro-lucca-braccini",fullName:"Alessandro Lucca Braccini"},{id:"79200",title:"Prof.",name:"Allan",surname:"Klynger da Silva Lobato",slug:"allan-klynger-da-silva-lobato",fullName:"Allan Klynger da Silva Lobato"},{id:"111434",title:"MSc.",name:"Gleberson",surname:"Guillen Piccinin",slug:"gleberson-guillen-piccinin",fullName:"Gleberson Guillen Piccinin"},{id:"176250",title:"MSc.",name:"Andréia",surname:"Kazumi Suzukawa",slug:"andreia-kazumi-suzukawa",fullName:"Andréia Kazumi Suzukawa"},{id:"176251",title:"Dr.",name:"Ricardo Shigueru",surname:"Okumura",slug:"ricardo-shigueru-okumura",fullName:"Ricardo Shigueru Okumura"},{id:"176252",title:"Dr.",name:"Claudete",surname:"Rosa da Silva",slug:"claudete-rosa-da-silva",fullName:"Claudete Rosa da Silva"},{id:"177319",title:"Dr.",name:"Daiane",surname:"de Cinque Mariano",slug:"daiane-de-cinque-mariano",fullName:"Daiane de Cinque Mariano"}],corrections:null},{id:"49557",title:"Complications with Controlling Insect Eggs",doi:"10.5772/61848",slug:"complications-with-controlling-insect-eggs",totalDownloads:2039,totalCrossrefCites:6,totalDimensionsCites:14,hasAltmetrics:0,abstract:"Eggs are difficult to kill because of the unique structure of the eggshell, comprised of multiple layers that have evolved to allow the embryo to breathe while simultaneously limiting water loss. The eggshell has been shown to be an excellent barrier to insecticides, fungal pathogens, and some fumigants. The insect eggshell contains only a few areas that could allow penetration of insecticides, the aeropyles and micropyles, which seem to be either so few in number or small in size that they do not allow a sufficient amount of insecticide through the eggshell. Resistance is also a contributing factor to control failures of insect eggs. Resistance in eggs has been documented in several insect species and a few studies have shown that some insect eggs produce elevated numbers of enzymes to break down insecticides. This chapter focuses on the structure and respiration of the insect eggshell as a barrier to insecticides and also covers various management strategies against insect eggs. Lastly, we discuss the few documentations of resistance in insect eggs thus far.",signatures:"Brittany E. Campbell, Roberto M. Pereira and Philip G. Koehler",downloadPdfUrl:"/chapter/pdf-download/49557",previewPdfUrl:"/chapter/pdf-preview/49557",authors:[{id:"157722",title:"Dr.",name:"Philip",surname:"Koehler",slug:"philip-koehler",fullName:"Philip Koehler"},{id:"175951",title:"Ms.",name:"Brittany",surname:"Campbell",slug:"brittany-campbell",fullName:"Brittany Campbell"},{id:"176310",title:"Dr.",name:"Roberto",surname:"Pereira",slug:"roberto-pereira",fullName:"Roberto Pereira"}],corrections:null},{id:"49305",title:"Current Status of the Insecticide Resistance in Aedes aegypti (Diptera: Culicidae) from Mexico",doi:"10.5772/61526",slug:"current-status-of-the-insecticide-resistance-in-aedes-aegypti-diptera-culicidae-from-mexico",totalDownloads:1820,totalCrossrefCites:4,totalDimensionsCites:9,hasAltmetrics:0,abstract:"The mosquito Aedes aegypti (Diptera: Culicidae) is the primary vector of dengue in Mexico and lately virus Chikungunya, although Aedes albopictus is widely distributed; its role in both diseases’ transmission has not been confirmed. The control of mosquitoes in Mexico includes source reduction consisting in the elimination of containers that are favorable sites for oviposition and development of the aquatic stage. The use of insecticides is to control larvae and adulticides as outdoor ultra-low volume applications and indoor residual spray and more recently impregnated materials. The health department regulates the use of insecticides, and such regulations are revised and adapted over time. Since 1999, the vector control regulations gave preference to the use of pyrethroids, a permethrin-based formulation to control adult forms. This insecticide was used as the only adulticide in Mexico for more than 10 years. The consequences of this actions have evolved in a widespread and strong resistance to other insecticides, mainly pyrethroids. We include in this revision evidence of resistance reported in Ae. aegypti in Mexico.",signatures:"Adriana E. Flores-Suarez, Gustavo Ponce-Garcia, Beatriz Lopez-\nMonroy, Olga Karina Villanueva-Segura, Iram Pablo RodriguezSanchez,\nJuan Ignacio Arredondo-Jimenez and Pablo Manrique-\nSaide",downloadPdfUrl:"/chapter/pdf-download/49305",previewPdfUrl:"/chapter/pdf-preview/49305",authors:[{id:"176037",title:"Dr.",name:"Adriana",surname:"Flores-Suárez",slug:"adriana-flores-suarez",fullName:"Adriana Flores-Suárez"},{id:"176038",title:"Dr.",name:"Gustavo",surname:"Ponce-García",slug:"gustavo-ponce-garcia",fullName:"Gustavo Ponce-García"},{id:"176039",title:"Dr.",name:"Beatriz",surname:"Lopez-Monroy",slug:"beatriz-lopez-monroy",fullName:"Beatriz Lopez-Monroy"},{id:"176040",title:"Dr.",name:"Pablo",surname:"Manrique-Saide",slug:"pablo-manrique-saide",fullName:"Pablo Manrique-Saide"},{id:"176224",title:"Dr.",name:"Juan Ignacio",surname:"Arredondo-Jiménez",slug:"juan-ignacio-arredondo-jimenez",fullName:"Juan Ignacio Arredondo-Jiménez"},{id:"176990",title:"MSc.",name:"Iram Pablo",surname:"Rodriguez-Sanchez",slug:"iram-pablo-rodriguez-sanchez",fullName:"Iram Pablo Rodriguez-Sanchez"},{id:"177033",title:"MSc.",name:"Olga Karina",surname:"Villanueva-Segura",slug:"olga-karina-villanueva-segura",fullName:"Olga Karina Villanueva-Segura"}],corrections:null},{id:"49257",title:"Mosquito-Borne Diseases, Pesticides Used for Mosquito Control, and Development of Resistance to Insecticides",doi:"10.5772/61510",slug:"mosquito-borne-diseases-pesticides-used-for-mosquito-control-and-development-of-resistance-to-insect",totalDownloads:3259,totalCrossrefCites:5,totalDimensionsCites:16,hasAltmetrics:0,abstract:"Mosquitoes are one of the most dangerous insects in the world for humanity. Over one million people worldwide die from mosquito-borne diseases every year. Mosquito vectored diseases include protozoan diseases, i.e., malaria, filarial diseases such as dog heartworm, and viral diseases such as dengue, encephalitis, and yellow fever. In addition, mosquitoes transmit several diseases and parasites that dogs and horses are very susceptible too. These include dog heartworm, West Nile virus (WNV), and eastern equine encephalitis (EEE). Since its discovery, chemical insecticides have represented the most widely method used to control mosquito-borne vectors. However, the effects of chemical insecticides on mosquito vector populations are usually transitory because vectors can rapidly develop resistance against them. Each insecticide triggers the selection of one or more mechanisms of resistance. These mechanisms include changes in the target site of action and metabolic detoxification among others.",signatures:"Jaime A. Cuervo-Parra, Teresa Romero Cortés and Mario Ramirez-\nLepe",downloadPdfUrl:"/chapter/pdf-download/49257",previewPdfUrl:"/chapter/pdf-preview/49257",authors:[{id:"76645",title:"Dr.",name:"Mario",surname:"Ramirez-Lepe",slug:"mario-ramirez-lepe",fullName:"Mario Ramirez-Lepe"},{id:"177394",title:"Dr.",name:"Jaime Alioscha",surname:"Cuervo-Parra",slug:"jaime-alioscha-cuervo-parra",fullName:"Jaime Alioscha Cuervo-Parra"},{id:"177395",title:"Dr.",name:"Teresa",surname:"Romero-Cortes",slug:"teresa-romero-cortes",fullName:"Teresa Romero-Cortes"}],corrections:null},{id:"49420",title:"Resistance and Its Management to Microbial and Insect Growth Regulator Larvicides in Mosquitoes",doi:"10.5772/61658",slug:"resistance-and-its-management-to-microbial-and-insect-growth-regulator-larvicides-in-mosquitoes",totalDownloads:2054,totalCrossrefCites:13,totalDimensionsCites:17,hasAltmetrics:0,abstract:"Mosquito larvicides derived from microbial organisms and insect growth regulators have been increasingly used to control mosquito larvae worldwide. Their relative target specificity, nontarget safety, and environmentally friendly profile have been well documented. The current chapter was intended to review and analyze the relevant information regarding resistance development and resistance management tactics. Bacillus thuringiensis israelensis de Bajac (B.t.i.) is a quick-acting and highly target-specific biopesticide against mosquitoes, blackflies, and other nematoceran species. Resistance development toward intact complementary toxin complex of B.t.i. was rare; however, low to high levels of resistance to individual toxins have occurred in laboratory mosquito populations. The toxins from bacterium Bacillus sphaericus Neide (recently renamed Lysinibacillus sphaericus Meyer and Neide) is another highly active larvicide against mosquitoes, toward which low to high levels of resistance have occurred in both laboratory and field mosquito populations. The Cyt1A toxin from B.t.i. and Mtx toxin from certain strains of B. sphaericus are the key components in resistance management to B.t.i. and B. sphaericus. The resistance management strategies have been well developed and implemented. Spinosad derived from Saccharopolyspora spinosa Mertz and Yao has been recently used for mosquito control; high levels of resistance and cross-resistance have occurred in laboratory mosquito populations and no management tactics have ever been developed. Methoprene has been used to control mosquitoes for decades, and low to high levels of resistance have been occasionally reported in both laboratory and field mosquito populations. Studies on mechanism and management of methoprene resistance are quite meager. Very little attention has been paid to the resistance management in mosquitoes to other insect growth regulators such as pyriproxyfen and diflubenzuron. The prevention of resistance and restoration of susceptibility in mosquitoes to these biorational larvicides are crucial to the success of sustainable integrated mosquito management.",signatures:"Tianyun Su",downloadPdfUrl:"/chapter/pdf-download/49420",previewPdfUrl:"/chapter/pdf-preview/49420",authors:[{id:"176406",title:"Ph.D.",name:"Tianyun",surname:"Su",slug:"tianyun-su",fullName:"Tianyun Su"}],corrections:null},{id:"49174",title:"Optimizing Strategic Insecticide Resistance Management Planning in Malaria Vectors",doi:"10.5772/61301",slug:"optimizing-strategic-insecticide-resistance-management-planning-in-malaria-vectors",totalDownloads:1926,totalCrossrefCites:2,totalDimensionsCites:2,hasAltmetrics:0,abstract:"In the past decade, there has been rapid scale-up of insecticide-based malaria vector control in the context of integrated vector management (IVM). But, the continued efficacy of vector control interventions is threatened by the selection of insecticide resistance. Evidence of insecticide resistance operationally undermining malaria vector control programmes is invariably mounting and is resulting in policy changes. Monitoring and management of resistant disease vectors is essential to limit the selection and spread of insecticide resistance and to maintain the effectiveness of vector control. Thus, countries are encouraged to implement pre-emptive insecticide resistance management (IRM) strategies against malaria vectors according to the Global Plan for IRM. However, substantial challenges for implementation exist at country level. The IVM strategy provides a potential platform that could be exploited for enhanced national strategic IRM planning and operationalisation. Nevertheless, significant coordinated response among stakeholders and political commitment is needed for timely and effective policy implementation within the context of a national health system.",signatures:"Emmanuel Chanda",downloadPdfUrl:"/chapter/pdf-download/49174",previewPdfUrl:"/chapter/pdf-preview/49174",authors:[{id:"175938",title:"Dr.",name:"Emmanuel",surname:"Chanda",slug:"emmanuel-chanda",fullName:"Emmanuel Chanda"}],corrections:null},{id:"49270",title:"Insecticide Resistance in East Africa — History, Distribution and Drawbacks on Malaria Vectors and Disease Control",doi:"10.5772/61570",slug:"insecticide-resistance-in-east-africa-history-distribution-and-drawbacks-on-malaria-vectors-and-dise",totalDownloads:1962,totalCrossrefCites:7,totalDimensionsCites:14,hasAltmetrics:0,abstract:"Malaria is a major contributor to the global disease burden and a significant impediment to socio-economic development in resource-poor countries. In contrast to improved trends of malaria morbidity and mortality in some parts of the world, malaria has remained a life threatening disease in many other regions including East Africa because of factors such as weak health systems, growing drug and insecticide resistance, ecological change, climate anomalies, socio-economic factors and changes in land use patterns. Ongoing malaria vector control strategies rely mainly on the use of indoor residual spraying (IRS) and insecticide treated nets (ITNs) which are the primary intervention strategies to reduce malaria burden. The current success in reducing malaria related morbidity and mortality has led to the optimism that elimination of the disease as a public health problem may be a realistic objective. Efforts during the last decades enabled access to ITNs in sub-Saharan Africa protecting millions of people at risk of malaria. The number of countries that employed IRS as a vector control strategy increased almost by two fold and the percentage of households owing at least one ITN in sub-Saharan Africa is estimated to increase from time to time. Currently, all ITNs are treated with pyrethroids while IRS depends on pyrethroids, DDT and recently on carbamates. Despite IRS and ITNs are known in reducing malaria incidence, insecticide resistance in malaria vectors threatens the success of malaria control program. Resistance to insecticides has occurred in most arthropod vectors with different mechanisms. If the current trends of increased insecticide resistance continue, it may jeopardise the efficacy of current vector control tools. Given the limited choice of available insecticides, i.e., only 12 insecticides belonging to 4 classes of insecticides (organochlorines, organophosphates, pyrethroids and carbamates), resistance to these insecticides has become a limiting factor for current efforts to sustain control. Currently, no other insecticide class with similar efficacy has been approved by WHOPES. The development of insecticide resistance in malaria vectors has been attributed to the prolonged use of insecticides for IRS and high coverage of ITNs/LLINs. The recent use of pyrethroids for indoor residual spraying is likely to have enhanced the selection pressure for insecticide resistance alleles among East African vector populations. Moreover, mosquitoes breeding in agricultural habitats are exposed to sub lethal doses of pesticides used in agriculture. Since currently recommended insecticides for IRS or ITNs were developed with similar active ingredients of pesticides used for agricultural pest control, their extensive and widespread use to boost agricultural productivity is believed to foster insecticide resistance in mosquito populations. There is strong evidence on the emergence of resistance to DDT and pyrethroids in the major malaria vectors in East Africa however, current information on resistance status of the malaria vectors in different areas of the sub-region is scarce. Genes conferring resistance to malaria vectors, including kdr, super kdr and acetylcholinesterase mutations and metabolic resistance are not mapped. The frequency and spatial distribution of East and West African kdr mutations and their association with the phenotypic resistance in East Africa is less understood. The bioassay results after WHO diagnostic tests in different East African malaria vector populations against insecticides used in public health is not well documented. In conclusion, planning and implementing insecticide resistance monitoring and management strategy should be part of the vector control program either for pre-emptive action without waiting for the development of resistance or to slowdown the spread of resistance in malaria vectors in the sub-region.",signatures:"Delenasaw Yewhalaw and Eliningaya J. Kweka",downloadPdfUrl:"/chapter/pdf-download/49270",previewPdfUrl:"/chapter/pdf-preview/49270",authors:[{id:"123576",title:"Prof.",name:"Eliningaya",surname:"Kweka",slug:"eliningaya-kweka",fullName:"Eliningaya Kweka"},{id:"175958",title:"Dr.",name:"Delenasaw",surname:"Yewhalaw",slug:"delenasaw-yewhalaw",fullName:"Delenasaw Yewhalaw"}],corrections:null},{id:"49298",title:"Emerging Insect-Borne Diseases of Agricultural, Medical and Veterinary Importance",doi:"10.5772/61467",slug:"emerging-insect-borne-diseases-of-agricultural-medical-and-veterinary-importance",totalDownloads:2067,totalCrossrefCites:3,totalDimensionsCites:11,hasAltmetrics:0,abstract:"Current migrations, due to several causes, but mainly consequence of climate changes, are causing several problems in Southern Europe. Some migrations are evident and attract attention immediately; others are silent, but still important, like several ones involving agriculture and livestock. In the future, a number of products employed in pest control may lose their efficacy. Pesticide resistance should be considered an increasing problem, and more environmental-friendly control approaches against arthropod pests are urgently needed. Two examples from the South of Italy clearly explain the kind of arising alerts and the complex network involving abiotic and biotic causes. The first case is the growing number of blue-tongue disease outbreaks, vectored by Culicoides sp. The second case is the alarm concerning the olive trees epidemic disease in Apulia, due to the bacterium Xylella fastidiosa. The development of new pest control methods is required in order to minimize negative effects of currently marketed synthetic pesticides. In this scenario, natural product research can afford solutions as part of an integrated pest control system. Preliminary results concerning the use of neem, Azadirachta indica, in control of insect vectors are discussed.",signatures:"Marcello Nicoletti, Kadarkarai Murugan and Giovanni Benelli",downloadPdfUrl:"/chapter/pdf-download/49298",previewPdfUrl:"/chapter/pdf-preview/49298",authors:[{id:"65501",title:"Prof.",name:"Marcello",surname:"Nicoletti",slug:"marcello-nicoletti",fullName:"Marcello Nicoletti"}],corrections:null},{id:"49941",title:"Insecticide Resistance and Fitness Cost",doi:"10.5772/61826",slug:"insecticide-resistance-and-fitness-cost",totalDownloads:2380,totalCrossrefCites:7,totalDimensionsCites:24,hasAltmetrics:0,abstract:"The intensive use of chemicals through decades has been selecting resistant populations of several insect species to distinct classes of insecticides, like neurotoxics, insect growth regulators, and toxins derived from bacteria. Insecticide resistance is nowadays a huge challenge for control programs of pests of rural practices and principally to the management of arthropod vector-borne diseases. Several behavioral, physiological, and molecular mechanisms can be selected for avoiding toxic effects of insecticides in the insect organism. These changes are genetic traits that arise randomly and spread throughout the population along time, under an environment with insecticide selective pressure. However, new rapidly achieved characteristics can present a fitness cost to their harbors, with negative effects in development and reproductive aspects. In this way, in the absence of insecticides, susceptible individuals may present reproductive advantages and then the population resistance levels would tend to decrease. If the selection pressure persists, however, compensatory genes known as modifiers can be selected, ameliorating the negative effects caused by the resistance genes themselves or their pleiotropic effects.",signatures:"Thiago Affonso Belinato and Ademir Jesus Martins",downloadPdfUrl:"/chapter/pdf-download/49941",previewPdfUrl:"/chapter/pdf-preview/49941",authors:[{id:"83198",title:"Prof.",name:"Ademir",surname:"Martins",slug:"ademir-martins",fullName:"Ademir Martins"}],corrections:null},{id:"49385",title:"A Review of Insecticide Resistance Status in Botswana",doi:"10.5772/61513",slug:"a-review-of-insecticide-resistance-status-in-botswana",totalDownloads:1632,totalCrossrefCites:3,totalDimensionsCites:3,hasAltmetrics:0,abstract:"For many decades, Botswana has been engaged in various malaria control activities that involved programmes that focused on the elimination of the malaria vector Anopheles arabiensis, by using DDT and pyrethroids. Despite the numerous and continuous application of these insecticides, studies have shown that there is susceptibility of this vector to DDT and pyrethroids in Botswana. Natural insecticides such as Bacillus thuringiensis and Spinosad, as alternatives to the use of chemicals, have shown to be effective against the eggs and larvae of DBM. Insect-resistant crop varieties were also found as alternatives in order to minimise insecticide resistance through the application of insecticides on insect infesting crops. The appearance of esterases B1 and A2–B2 in the Gaborone and Molepolole strains of Culex, respectively, indicates dispersion of these esterases through human migration.",signatures:"N.M. Makate",downloadPdfUrl:"/chapter/pdf-download/49385",previewPdfUrl:"/chapter/pdf-preview/49385",authors:[{id:"176112",title:"Dr.",name:"Ntebaleng",surname:"Makate",slug:"ntebaleng-makate",fullName:"Ntebaleng Makate"}],corrections:null},{id:"49354",title:"Effect of Imidacloprid on Bacterial Soil Isolate Bacillus weihenstephanensis",doi:"10.5772/61503",slug:"effect-of-imidacloprid-on-bacterial-soil-isolate-bacillus-weihenstephanensis",totalDownloads:1547,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:"Imidacloprid is a chloronicotinyl insecticide used widely to control biting and sucking insects. The over accumulation of this pesticide in environment requires higher awareness about this pesticide. Present investigation was carried out to analyze the effect of imidacloprid on antioxidant enzymes such as superoxide dismutase, catalase and peroxidase in soil isolate Bacillus weihenstephanensis isolated after laboratory and field studies on the toxic effect of imidacloprid. Further, the genes for the three enzymes involved in the antioxidant defense process in soil isolate Bacillus weihenstephanensis were sequenced and identified. Study on the effect of 10–7 to 10–3 molar concentrations of imidacloprid for a period of 24, 48, 72 and 96 h on three antioxidant enzymes superoxide dismutase, catalase and peroxidase in Bacillus weihenstephanensis showed that there was an increase in the activity of all the three antioxidant enzymes. The enzyme activity increased with an increase in the concentration of insecticide proving that the inhibitory effect is dose-dependent. Further, sequencing revealed that Fe/MnSOD (sod A), hydroxyperoxidase HP(II) (Kat E) and glutathione peroxidase genes were expressed in response to stress induced by imidacloprid treatment in Bacillus weihenstephanensis. The present investigation indicates that imidacloprid induces the expression of antioxidant enzymes in the soil isolate Bacillus weihenstephanensis. The synthesis of antioxidant enzymes may be helping Bacillus weihenstephanensis in resisting the toxic effects of imidacloprid.",signatures:"A.A. Shetti and B.B. Kaliwal",downloadPdfUrl:"/chapter/pdf-download/49354",previewPdfUrl:"/chapter/pdf-preview/49354",authors:[{id:"78330",title:"Dr.",name:"Basappa",surname:"Kaliwal",slug:"basappa-kaliwal",fullName:"Basappa Kaliwal"}],corrections:null},{id:"49288",title:"Resistance in Bacteria",doi:"10.5772/61479",slug:"resistance-in-bacteria",totalDownloads:1866,totalCrossrefCites:1,totalDimensionsCites:5,hasAltmetrics:0,abstract:"Resistance is the result of bacteria evolving new genes in response to the presence of pesticide and antibiotics. In our society day by day, a number of chemicals, pesticides, and antibiotics are introducing due to the result of resistance development of bacteria. Pesticides are added to the environment for the purpose of killing or injuring some form of life. Pesticide resistance describes the decreased susceptibility of a pest population to a pesticide that was previously effective at controlling the pest. Bacteria have been used extensively for bioremediation purposes. The ability of organisms to bioremediate pesticides is mainly based on their biodegradation activity. Methomyl and imidacloprid are widely using throughout the world as a pesticide. Many pesticide degradation genes present in soil bacteria have been shown to reside on plasmids or genome, a common location for other degradation genes. The excessive use of pesticides and antibiotic leads and promotes the development of resistance in the bacteria. An increase in the frequency of antibiotic resistance in bacteria since the 1950s has been observed for all major classes of antibiotics used to treat a wide variety of diseases. Development of resistance is a major concern for another reason of human and animal health. Antibiotic resistance profiles of the isolates must be done earlier to the use of antibiotics in both to choose appropriate antibiotic for treatment and prevention of the disease. Research into newer antibiotics continues, measures can and should be taken to reverse the practices that promote the development of antibiotic resistance in bacteria.",signatures:"S.O. Sadashiv and Basappa B. Kaliwal",downloadPdfUrl:"/chapter/pdf-download/49288",previewPdfUrl:"/chapter/pdf-preview/49288",authors:[{id:"78330",title:"Dr.",name:"Basappa",surname:"Kaliwal",slug:"basappa-kaliwal",fullName:"Basappa Kaliwal"},{id:"176334",title:"Dr.",name:"Sadashiv",surname:"S. O.",slug:"sadashiv-s.-o.",fullName:"Sadashiv S. O."}],corrections:null},{id:"49761",title:"The Role of Glutathione Transferases in the Development of Insecticide Resistance",doi:"10.5772/61972",slug:"the-role-of-glutathione-transferases-in-the-development-of-insecticide-resistance",totalDownloads:1909,totalCrossrefCites:3,totalDimensionsCites:5,hasAltmetrics:0,abstract:"Glutathione transferases are multifunctional enzymes. Some of the known functions of the enzymes are biotransformation of xenobiotics, countering oxidative stress and participating in cell regulatory functions. As the isoforms present in number of classes the purification of a particular isoform for characterization is a challenging task. In insect, the study of GSTs is focusing on their roles in development of insecticide resistance. There were evident that certain classes of the enzymes are reactive towards conjugating the pesticides. This makes GSTs one of the enzymes of intention in the discipline of pesticide control management.",signatures:"Zazali Alias",downloadPdfUrl:"/chapter/pdf-download/49761",previewPdfUrl:"/chapter/pdf-preview/49761",authors:[{id:"176212",title:"Dr.",name:"Zazali",surname:"Alias",slug:"zazali-alias",fullName:"Zazali Alias"}],corrections:null},{id:"49576",title:"Biological and Biochemical Bases of Pesticides Resistance in Rhipicephalus (Boophilus) microplus",doi:"10.5772/61839",slug:"biological-and-biochemical-bases-of-pesticides-resistance-in-rhipicephalus-boophilus-microplus",totalDownloads:1839,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Several arthropod species are important vectors of pathogens that cause disease in humans, animals, and plants, including protozoa, nematodes, bacteria, and viruses. Arthropods are also pests competing with humans for food and parasitize farm animals, decreasing their productivity. Historically, arthropod pests and disease vectors affecting public health, crop yields, and livestock production have been managed through the intensive use of pesticides. The widespread use of pesticides is a major problem because most of the economically important arthropod species have developed resistance to currently used pesticides. The impact of pesticide resistance is multifactorial and involves losses due to the heavy use of pesticides, environmental pollution, decreased profitability, food contamination, and public health problems due to pesticide exposure. An indirect consequence of pesticide resistance is the mortality caused by arthropod-borne diseases such as dengue and malaria in humans and babesiosis and anaplasmosis in cattle. The understanding of molecular mechanisms and adaptations to resistance in arthropods is an important issue. However, the molecular mechanisms of pesticide resistance remain to be fully understood. Understanding of resistance mechanisms will contribute significantly to improve integrated managements programs and to discover new targets for vaccine development to mitigate the effects of pesticide-resistant arthropods on agriculture and public health.",signatures:"Rodrigo Rosario-Cruz and Delia Inés Domínguez-García",downloadPdfUrl:"/chapter/pdf-download/49576",previewPdfUrl:"/chapter/pdf-preview/49576",authors:[{id:"176211",title:"Ph.D.",name:"Rodrigo",surname:"Rosario-Cruz",slug:"rodrigo-rosario-cruz",fullName:"Rodrigo Rosario-Cruz"},{id:"176225",title:"Dr.",name:"Delia Ines",surname:"Domínguez-García",slug:"delia-ines-dominguez-garcia",fullName:"Delia Ines Domínguez-García"}],corrections:null},{id:"49628",title:"Biochemical Insecticide Resistance in Tea Pests",doi:"10.5772/61949",slug:"biochemical-insecticide-resistance-in-tea-pests",totalDownloads:2262,totalCrossrefCites:4,totalDimensionsCites:5,hasAltmetrics:0,abstract:"Polyphagous insect herbivores encounter numerous toxins (xenobiotics) as they pass through their life cycle; some toxins are produced naturally by the host plants (allelochemicals) and others by humans (insecticides) to manage these insects having pest status. The host plants have evolved defensive mechanisms for protection from herbivory, including chemical repellents and toxins (secondary metabolites). Many classes of insect repellents and toxic substances, such as isoflavonoids, furanocoumarins, terpenoids, alkaloids and cyanogenic glycosides are synthesized in plants. The biosynthetic pathways leading to these allelochemicals are continually evolving to generate new secondary metabolites. Similarly, to control the herbivorous insect pests, numerous chemicals of synthetic origin are used continuously against them. In response, the attacking organisms also evolve mechanisms that enable them to resist the defensive chemicals of their hosts and those toxins of synthetic origin applied for their control. A variety of defence mechanisms, including enzymatic detoxification systems, physiological tolerance and behavioural avoidance, protect insect herbivores from these xenobiotic compounds. Insect pests have evolved the mechanisms to degrade metabolically (enzymatically) or otherwise circumvent the toxic effect of many types of chemicals that we have synthesized as modern insecticides. The extent to which insects can metabolize and thereby degrade these antibiotics or toxins is of considerable importance for their survival in hostile chemical environment. These mechanisms continue to evolve as insects attempt to colonize new plant species or encounter newer molecules of synthetic insecticides. Generally, three main enzymes, general esterases (GEs), glutathione S-transferases (GSTs) and cytochrome P450-mediated monooxygenases (CYPs), are involved in the process of metabolic detoxification of insecticides. During the past 70 years, following the discovery and extensive use of synthetic insecticides, resistance of insects to insecticides has registered the greatest increase and strongest impact. The evolution of resistance to insecticides is an example of evolutionary process. An insecticide is the selection pressure, which results in a very strong but differential fitness of the individual in a population having susceptible and resistant genotypes. The survival and subsequent reproduction of resistant individuals lead to a change in the frequency of alleles conferring resistance in the population over time. While selection pressure acts to change allele frequencies within pest populations, the phenotype upon which selection operates is a function of both genotype and the environment. Recent studies in insect detoxifying enzymes have revealed further versatility in the adaptation of insects to their environment by the phenomenon of induction. This is the process in which a chemical stimulus enhances the activity of the detoxification enzyme systems by the production of additional enzymes that metabolize toxic chemical substances. Hence, the influence of environmental factors such as continuous usage of insecticides and the chemical constituents (allelochemicals) of host plants on phytophagous insects can have a great impact to induce the enzymatic detoxification systems of insects, thereby promoting the insecticide resistance mechanisms. While all insects do possess detoxification ability, its magnitude is expected to vary among the species with the nature of its recent environment and feeding ecology. The level and type of detoxifying mechanisms differ greatly, which therefore result in varying toxicity among different developmental stages, species and populations. Variation in detoxifying enzyme activity is responsible in part for the selective toxicity of different insecticides, the development of resistance to insecticides and selective adaptation to host plants. Over-expression of these detoxifying enzymes, capable of metabolizing insecticides, can result in a high level of metabolic tolerance/resistance to synthetic insecticides. Increased expressions of genes encoding the major xenobiotic metabolizing enzymes are the most common cause of insecticide resistance in insects.",signatures:"Dhiraj Saha",downloadPdfUrl:"/chapter/pdf-download/49628",previewPdfUrl:"/chapter/pdf-preview/49628",authors:[{id:"176292",title:"Dr.",name:"Dhiraj",surname:"Saha",slug:"dhiraj-saha",fullName:"Dhiraj Saha"}],corrections:null},{id:"49233",title:"The Role of Volatile Substances Emitted by Cultivated Plant's Roots in Indirect Defense Against Soil Herbivores",doi:"10.5772/61369",slug:"the-role-of-volatile-substances-emitted-by-cultivated-plant-s-roots-in-indirect-defense-against-soil",totalDownloads:1631,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Plants in nature have developed many defense mechanisms to defend themselves against attacks by harmful organisms; these mechanisms are indirect and direct. When attacked by a harmful organism, many plant species release volatile substances that attract natural enemies of herbivores. Volatile substances have an important role in the tritrophic system consisting of a plant, a herbivore, and its natural enemy. They function as a kind of chemical signal (semiochemical) which directly influences both harmful pests and their natural enemy. Some of these substances appear on damaged as well as undamaged plants, while other substances are released in the case of mechanic damage or feeding of a particular herbivore species. Volatile substances may repel a herbivore. Harmful pests have an important role in attracting natural enemies, as they also emit chemical signals that function as kairomones for natural enemies. In order to increase our knowledge in the field of indirect plant defense we studied chemosensation of four entomopathogenic nematode species (Steinernema, Heterorhabditis) to compounds released by insect (wireworms and grubs) damaged and undamaged potato and carrot roots, and mechanically damaged maize roots. The aim of our research was (1) to study the effect of different EPN foraging strategies (ambush, intermediate, or cruise) toward the tested volatile compounds, (2) to determine whether chemotaxis is species-specific, and (3) to assess whether the volatile compounds from damaged and undamaged roots have any behavioral effects on the EPNs studied, and (4) if volatile compounds are a part of an indirect plant defense. Our results indicate that all of the tested EPN species exhibited attraction (or repulsion) to volatiles, irrespective of their foraging strategy, and suggest that responses to distinct volatile cues are a species-specific characteristic. These results expand our knowledge of volatile compounds as cues, which may be used by EPNs to find hosts and for other aspects of navigation in soil.",signatures:"Žiga Laznik and Stanislav Trdan",downloadPdfUrl:"/chapter/pdf-download/49233",previewPdfUrl:"/chapter/pdf-preview/49233",authors:[{id:"78285",title:"Prof.",name:"Stanislav",surname:"Trdan",slug:"stanislav-trdan",fullName:"Stanislav Trdan"},{id:"78340",title:"Dr.",name:"Žiga",surname:"Laznik",slug:"ziga-laznik",fullName:"Žiga Laznik"}],corrections:null},{id:"49223",title:"About Previous Investigations Regarding the Role of Glucosinolates in Controlling Brassica Insect Pests in Slovenia",doi:"10.5772/61444",slug:"about-previous-investigations-regarding-the-role-of-glucosinolates-in-controlling-brassica-insect-pe",totalDownloads:1583,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The chapter presents previous field and laboratory investigations of cabbage flea beetles (Phyllotreta spp.) and cabbage stink bugs (Eurydema spp.) interactions with different Brassica crops in Slovenia. The special emphasis is given to an influence of different glucosinolates on injuries caused by mentioned economically important two genera of insect pests. In the study, we found out that the content of glucosinolates differs between different Brassica species, as well as between individual plant organs of the same species. The content of glucosinolates is conditioned also by environmental influences. Among the analysed glucosinolates, glucobrassicin was presented in all plant species. In almost all plant species, it inhibited the feeding of cabbage flea beetles, except in oil rape, where it had stimulative effects. We have established that the influence of individual glucosinolate on Phyllotreta spp. and Eurydema spp. is not identical as it differs between individual plant species. Because of the variability of glucosinolates as well as different preferences of the studied groups of harmful pests in regard to the plant species, one of the options for diminishing the damage caused by cabbage stink bugs and cabbage flea beetles is the use of mixed Brassica crops for trapping the pests in the growing season. In the future, glucosinolates should be employed to a greater extent in environmentally acceptable ways of food production, one of which is also the use of trap crops in order to reduce harmful effects of cabbage stink bugs.",signatures:"Tanja Bohinc and Stanislav Trdan",downloadPdfUrl:"/chapter/pdf-download/49223",previewPdfUrl:"/chapter/pdf-preview/49223",authors:[{id:"176249",title:"Dr.",name:"Tanja",surname:"Bohinc",slug:"tanja-bohinc",fullName:"Tanja Bohinc"},{id:"176280",title:"Prof.",name:"Stanislav",surname:"Trdan",slug:"stanislav-trdan",fullName:"Stanislav Trdan"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"3055",title:"Insecticides",subtitle:"Development of Safer and More Effective Technologies",isOpenForSubmission:!1,hash:"adb06e05715aa4d3ec42f707d1626158",slug:"insecticides-development-of-safer-and-more-effective-technologies",bookSignature:"Stanislav Trdan",coverURL:"https://cdn.intechopen.com/books/images_new/3055.jpg",editedByType:"Edited by",editors:[{id:"78285",title:"Prof.",name:"Stanislav",surname:"Trdan",slug:"stanislav-trdan",fullName:"Stanislav Trdan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2036",title:"Insecticides",subtitle:"Advances in Integrated Pest Management",isOpenForSubmission:!1,hash:"42dc69ce20386f76845e38275b0e54e8",slug:"insecticides-advances-in-integrated-pest-management",bookSignature:"Farzana Perveen",coverURL:"https://cdn.intechopen.com/books/images_new/2036.jpg",editedByType:"Edited by",editors:[{id:"75563",title:"Dr.",name:"Farzana Khan",surname:"Perveen",slug:"farzana-khan-perveen",fullName:"Farzana Khan Perveen"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5252",title:"Integrated Pest Management (IPM)",subtitle:"Environmentally Sound Pest Management",isOpenForSubmission:!1,hash:"8f2c00d77debd573ce98ad0af592512a",slug:"integrated-pest-management-ipm-environmentally-sound-pest-management",bookSignature:"Harsimran Kaur Gill and Gaurav Goyal",coverURL:"https://cdn.intechopen.com/books/images_new/5252.jpg",editedByType:"Edited by",editors:[{id:"169846",title:"Dr.",name:"Harsimran",surname:"Gill",slug:"harsimran-gill",fullName:"Harsimran Gill"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. 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Unfortunately solutions to differential equations can rarely be expressed by closed formulas and numerical methods are needed to approximate their solutions. There are many numerical methods for approximating the solution to differential equations including the finite difference (FD), finite element (FE), finite volume (FV), spectral, and discontinuous Galerkin (DG) methods. These methods are used when the mathematical equations are too complicated to be solved analytically.
The FE method has become the standard numerical scheme for approximating the solution to many mathematical problems; see [1, 2, 3, 4, 5, 6, 7, 8, 9] and the references therein just to mention a few. In simple words, the FE method is a numerical method to solve differential equations by discretizing the domain into a finite mesh. Numerically speaking, a set of differential equations are converted into a set of algebraic equations to be solved for unknown at the nodes of the mesh. The FE method originated from the need to solve complex elasticity and structural analysis problems in civil and aeronautical engineering. The first development can be traced back to the work by Hrennikoff in 1941 [10] and Courant in 1943 [11]. Although these pioneers used different perspectives in their FE approaches, they each identified the one common and essential characteristic: mesh discretization of a continuous domain into a set of discrete sub-domains, usually called elements. Another fundamental mathematical contribution to the FE method is represented by Gilbert Strang and George Fix [12]. Since then, the FE method has been generalized for the numerical modeling of physical systems in many engineering disciplines including electromagnetism, heat transfer, and fluid dynamics.
The advantages of this method can be summarized as follows:
Numerical efficiency: The discretization of the calculation domain with finite elements yields matrices that are in most cases sparse and symmetric. Therefore, the system matrix, which is obtained after spatial and time discretization, is sparse and symmetric too. Both the storage of the system matrix and the solution of the algebraic system of equations can be performed in a very efficient way.
Treatment of nonlinearities: The modeling of nonlinear material behavior is well established for the FE method (e.g., nonlinear curves, hysteresis).
Complex geometry: By the use of the FE method, any complex domain can be discretized by triangular elements in 2D and by tetrahedra elements in 3D.
Applicable to many field problems: The FE method is suited for structural analysis, heat transfer, electrical/magnetical analysis, fluid and acoustic analysis, multi-physics, etc.
COMSOL Multiphysics (known as FEMLAB before 2005) is a commercial FE software package designed to address a wide range of physical phenomena. It is widely used in science and industry for research and development. It excels at modeling almost any multi-physics problem by solving the governing set of PDEs via the FE method. This software package is able to solve one, two and three-dimensional problems. It comes with a modern graphical user interface to set up simulation models and can be scripted from Matlab or via its native Java API.
In this chapter, we introduce the FE method for several one-dimensional and two-dimensional model problems. Although the FE method has been extensively used in the field of structural mechanics, it has been successfully applied to solve several other types of engineering problems, such as heat conduction, fluid dynamics, seepage flow, and electric and magnetic fields. These applications prompted mathematicians to use this technique for the solution of complicated problems. For illustration, we will use simple one-dimensional and two-dimensional model problems to introduce the FE method.
We first present the FE method as an approximation technique for solving the following first-order initial-value problem (IVP) using piecewise linear polynomials
In order to apply the FE method to solve this problem, we carry out the following process.
Derive a weak form (variational formulation). This can be done by multiplying the ODE in (1) by a test function
Generate a triangulation (also called a mesh) of the computational domain
Define a finite dimensional space over the triangulation: Let the solution
Define the FE space as the set of all continuous piecewise linear polynomials
We remark that any function
Construct a set of basis functions based on the triangulation. Since
A continuous piecewise linear function
There are infinite number of sets of basis functions. We should choose a set of basis functions that are simple, have compact (minimum) support (that is, zero almost everywhere except for a small region), and meet the regularity requirement, that is, they have to be continuous, and differentiable except at nodal points. The simplest ones are the so-called hat functions satisfying
Approximate the exact solution
This type of FE method (with similar trial and test space) is sometimes called a Galerkin method, named after the famous Russian mathematician and engineer Galerkin.
since
A typical hat function
Finally, we solve the linear system for
However, for
Similarly, for
We next calculate
Thus, we obtain the following linear system of equations
The determinant of the above matrix is
Finally, we solve the linear system for
Following the same steps used for the case
Here, we extend the FE method for the nonlinear IVP using piecewise linear polynomials
The FE method consists of finding
Writing
where
Let
Similarly,
Using Simpson’s Rule
However, for
Next, we compute the Jacobian matrix with entries
We already computed the entries
Using Simpson’s Rule, we get
Here, we shall study the derivation and implementation of the FE method for two-point boundary-value problems (BVPs). For easy presentation, we consider the following model problem: Find
where
The model problem (3) can be reformulated into three different forms:
(D)-form: the original differential equation (3).
(V)-form: the variational form or weak form:
(M)-form: the minimization form:
Under some assumptions, the three different forms are equivalent, that is, they have the same solution as will be explained in the following theorem.
(D) is equivalent to (V), (V) is equivalent to (M), and (M) is equivalent to (D).
To solve (3) using the FE method, we carry out the process described below. Usually, a FE method is always derived from the weak or variational formulation of the problem at hand.
since
We want to find
If
Conversely, if
Existence and uniqueness of weak solutions is obtained by the Lax-Milgram Theorem.
We can consider solutions with lower regularity using the weak formulation.
FE method gives an approximation of the weak solution.
From now on, we use the notation
The matrix
It is natural to obtain an approximation
We call
It is easy to show that
Let
The explicit expressions for the hat function
for
We call
It can be shown that (6) is equivalent to the
where
We can use either the weak/variational form (V), or the minimization form (M), to derive a linear system of equations for the coefficients
Substituting (8) into (7) yields
The problem (7) is now equivalent to the following: Find the real numbers
We note that the linear system (9) is equivalent to the system in matrix–vector form
where
and
To obtain the approximate solution we need to solve the linear system for the unknown vector
The Ritz method is one of the earliest FE methods. However, not every problem has a minimization form. The minimization form for the model problem (3) is
As before, we look for an approximate solution of the form (8). If we plug this into the functional form above, we get
which is a multi-variable function of
Exchange the order of integration and the summation, we get
which is exactly the same linear system (9) obtained using the Galerkin method.
It is straightforward to calculate the entries
Furthermore, if
By symmetry, we also have
To obtain
So, we can easily verify that
where
Finally, we obtain the following system:
Finally, we obtain the following system:
which is the same system obtained using the finite difference method, where
Next, we state a general convergence result for the Galerkin method. We first define the following norm and semi-norm: For
where
Next, we study the convergence of
Since
This inequality suggest that the error between
where
If the partition is not uniform then we obtain the same error estimate with
The error is expressed in terms of the exact solution
The norm
In problem (3) we considered a homogeneous Dirichlet boundary conditions. Here, we extend the FE method to boundary conditions of different types. There are three important types of boundary conditions (BCs):
Dirichlet BCs:
Neumann BCs:
Robin BCs:
Note that any combination is possible at the two boundary points.
where
since
Let
It can be shown that (17) is equivalent to the
Expanding
where the coefficients
Substituting (19) into (18) yields
which is a
where
For simplicity we assume the partition is uniform so that
It is straightforward to calculate the entries of the stiffness matrix. For
where we have used that
Changing
Thus the stiffness matrix is
The entries
We note that
where
Multiplying (23) by a function
Since
Hence, the weak or variational form of (23) reads: Given
The FE space
with
Let us consider the following two-point BVP: find
where
Multiplying (26) by a function
We gather all
The FE method consists of finding
which is a
and
Let for simplification
Let
and its subspace
where
with
Figure 3 shows the global shape functions for the space
(left) global shape functions for the space
where
with
The variational formulation of the internal approximation of the Dirichlet BVP (3) consists now in finding
Here, it is convenient to introduce the notation
where
where
and load vector
Since the shape functions
Hence, the shape functions can be reduced to only three basic shape functions (Figure 3):
Their respective derivatives are
This approach consists in considering all computations on an interval
In this case, the elementary contributions of the element
Thus, the problem is reduced to computing the integrals
Consider the following two-point BVP: find
where
Multiplying (29) by a function
Hence, the weak or variational form of (29) reads: Given
Let
The FE method scheme consists of finding
Introduce the notation
where
where
and the load vector
Clearly, the only extra terms are given in the vector with entries
Suppose
Here, we apply the FE method for two-dimensional elliptic problem: Find
where
Let
Let
This means that triangle
The Delaunay algorithm determine a triangulation with the given points as triangle nodes. Delaunay triangulations are optimal in the sense that the angles of all triangles are maximal.
Matlab has a built in toolbox called PDE Toolbox and includes a mesh generation algorithm.
Let
Now let
This is solvable due to
where
Let
Solving the systems, we get
Let
Functions in
Given
in particular
where
Now, we consider the piecewise continuous interpolant
where
Let
The problem of finding
where
Since
The problem can be expressed as a linear system of equations
In general, we use a quadrature rule to approximate integrals. The general form is
where the
The FE method was designed to approximate solutions to complicated equations of elasticity and structural mechanics, usually modeled by elliptic type equations, with complicated geometries. It has been developed for other applications as well.
Consider the following two-dimensional elliptic problem: Find
where
In order to derive the weak formulation, we multiply (31) with
We obtain the weak form: Find
We can formulate the method as in the 1D case by using the weak formulation (32). The FE method in 2D is defined as follows: Find
where
This gives us the system
where
In general we have
Furthermore, we obviously have
where
Given
Consider the following Dirichlet Problem: Find
where
So the weak problem reads: Find
Assume that
Assume that we have
where
Consider the following Neumann Problem: Find
where
Thus, the variational formulation reads: find
In order to guarantee solvability, we note that if
Therefore we need to assume the following compatibility condition
to ensure that a solution can exist. Note that if
which contains only functions with a zero mean value. This is a called a quotient space. This space guarantees a unique weak solution (with weak formulation as usual with test functions in
Now, the FE method takes the form: find
where
Here we describe briefly how Neumann conditions are handled in two-dimensional finite elements. Suppose
where
Multiplying (36) by a test function
since
We now restrict our discussion once more to two-dimensional polygonal domains. To apply the FE method, we must choose an approximating subspace of
A basis for
In a two-dimensional problem, inhomogeneous boundary conditions are handled just as in one dimension. Inhomogeneous Dirichlet conditions are addressed via the method of shifting the data (with a specially chosen piecewise linear function), while inhomogeneous Neumann conditions are taken into account directly when deriving the weak form. Both types of boundary conditions lead to a change in the load vector.
The method of shifting the data can be used to transform an inhomogeneous Dirichlet problem to a homogeneous Dirichlet problem. This technique works just as it did for a one-dimensional problem, although in two dimensions it is more difficult to find a function satisfying the boundary conditions. We consider the BVP
where
Suppose we find a function
and
Finally, the solution
We now describe a method for computing a function
A direct calculation shows that
We then define
We have thus replaced each
Finally, we define
The reader should notice how the second term interpolates between the boundary values on
We can also apply the technique of shifting the data to transform a BVP with inhomogeneous Neumann conditions to a related BVP with homogeneous Neumann conditions. However, the details are somewhat more involved than in the Dirichlet case. Consider the following BVP with the Neumann conditions
where
We make the following observation: If there is a twice-continuously differentiable function
which together imply that
We will assume that (41) holds.
We now explain how to compute a function that satisfies the desired Neumann conditions. The method is similar to that used to shift the data in a Dirichlet problem: we will “interpolate” between the Neumann conditions in each dimension and arrange things so that the two interpolations do not interfere with each other. We use the fact that
The first step is to transform the boundary data
We can satisfy these conditions with a function of the form
If
We can now define
Then
Consider the following Eigenvalue Problem: Find
In order to derive the weak formulation, we multiply (43) with
We obtain the weak form: Find
The FE method in 2D is defined as follows: Find
where
This leads to an algebraic system of the form
Consider the following model Problem: Find
The weak form: Find
The FE approximation is defined as follows: Find
where
This leads to system of the form
Now, let
There are two different kinds of error estimates,
Consider the following convection-diffusion problem: Find
We seek a weak solution
Note that there is no need to apply Green’s formula to
The FE method in 2D is defined as follows: Find
where