Carol Davila University of Medicine and Pharmacy

CRISTINA MANUELA DRĂGOI is associate professor at the Department of Biochemistry, Faculty of Pharmacy, University of Medicine and Pharmacy 'Carol Davila', Bucharest, Romania. She has professional and academic experience in antioxidants mechanisms, in assessing drugs effects on antioxidant processes and endogenous indoles modulatory actions. She has been fascinated by melatonin, the pineal hormone, which she has studied under different circumstances, assessed its interactions with DNA, performed research on its effects in association with other therapeutic agents, using different animal models and cell lines. Her scientific interest focuses on revealing melatonin's actions on major physiological processes, as pregnancy or aging, determining its modulatory abilities in different stages of fetus evolution, in healthy aging mechanisms and in preventing neurodegeneration. This captivating subject of applied biochemistry in drug research is the core of her scientific research projects. Mrs. Drăgoi has a great interest in nutrition strategies applied in the clinical field, modulating the energy metabolism in cancerous states, mitochondrial and neurological diseases. She runs the nutritional biochemistry module within the master program 'Nutrition and Food Safety'. The field of nutrition and dietetics has been one of her active concerns, elaborating a series of scientific papers in this field.

1books edited

4chapters authored

Latest work with IntechOpen by CRISTINA MANUELA DRĂGOI

Melatonin, the pineal neurohormone, is a pleiotropic molecule acting in the center of the integrative molecular mechanisms of the organism, based on interconnections of the regulatory systems: neural, endocrine, immune, and genetic, conveying into the uniqueness of human architecture. This book provides a systematic and updated overview of melatonin biochemical mechanisms of action, pharmacological features, and clinical uses, clutching the subject with complete details of pharmaceutical formulations designed for different routes of administration and different health issues, aiming at optimal melatonin bioavailability when therapeutically delivered. The book addresses a broad range of audiences, from healthcare professionals, medically and pharmaceutically based, to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge of the physiological and pathological implications of melatonin and its metabolites.

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