Chronic heart failure (CHF) was characterized by the failure of enough blood supply from the heart to meet the body’s metabolic demands, and the prevalence of CHF continuously increases globally. The personalized diagnosis of Traditional Chinese Medicine (TCM) classifies CHF into several different syndrome types, and integrating Western and TCM to treat CHF has proved a validated therapeutic approach. Over the last few years, there has been a rapidly growing number of metabolomics applications aimed at finding biomarkers that could assist diagnosis, provide therapy guidance, and evaluate response to therapy for individualized intervention of CHF. Thus, in this review, particular attention will be paid to the past successes in applications of state-of-the-art technology on metabolomics to contribute to biomarker discovery in CHF research.
Part of the book: Metabolomics