Overview of the variables.
\\n\\n
More than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\\n\\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\\n\\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\\n\\nAdditionally, each book published by IntechOpen contains original content and research findings.
\\n\\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\\n\\n\\n\\n
\\n"}]',published:!0,mainMedia:{caption:"IntechOpen Maintains",originalUrl:"/media/original/113"}},components:[{type:"htmlEditorComponent",content:'
Simba Information has released its Open Access Book Publishing 2020 - 2024 report and has again identified IntechOpen as the world’s largest Open Access book publisher by title count.
\n\nSimba Information is a leading provider for market intelligence and forecasts in the media and publishing industry. The report, published every year, provides an overview and financial outlook for the global professional e-book publishing market.
\n\nIntechOpen, De Gruyter, and Frontiers are the largest OA book publishers by title count, with IntechOpen coming in at first place with 5,101 OA books published, a good 1,782 titles ahead of the nearest competitor.
\n\nSince the first Open Access Book Publishing report published in 2016, IntechOpen has held the top stop each year.
\n\n\n\nMore than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\n\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\n\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\n\nAdditionally, each book published by IntechOpen contains original content and research findings.
\n\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\n\n\n\n
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"749",leadTitle:null,fullTitle:"Explicative Cases of Controversial Issues in Neurosurgery",title:"Explicative Cases of Controversial Issues in Neurosurgery",subtitle:null,reviewType:"peer-reviewed",abstract:"Neurosurgery is a rapidly developing field of medicine. Therefore, staying keeping track of the advancements in the field is paramount for trainees as well as fully trained neurosurgeons. This book, fully available online, is a part of our effort of improving availability of medical information for anyone who needs to keep up-to-date.",isbn:null,printIsbn:"978-953-51-0623-4",pdfIsbn:"978-953-51-7005-1",doi:"10.5772/1256",price:159,priceEur:175,priceUsd:205,slug:"explicative-cases-of-controversial-issues-in-neurosurgery",numberOfPages:546,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"ba447398ca3b67eb3d9978174712132a",bookSignature:"Francesco Signorelli",publishedDate:"May 23rd 2012",coverURL:"https://cdn.intechopen.com/books/images_new/749.jpg",numberOfDownloads:91144,numberOfWosCitations:30,numberOfCrossrefCitations:19,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:49,numberOfDimensionsCitationsByBook:0,hasAltmetrics:0,numberOfTotalCitations:98,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 1st 2011",dateEndSecondStepPublish:"March 29th 2011",dateEndThirdStepPublish:"August 3rd 2011",dateEndFourthStepPublish:"September 2nd 2011",dateEndFifthStepPublish:"December 31st 2011",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"74494",title:"Dr.",name:"Francesco",middleName:null,surname:"Signorelli",slug:"francesco-signorelli",fullName:"Francesco Signorelli",profilePictureURL:"https://mts.intechopen.com/storage/users/74494/images/system/74494.jpg",biography:"Prof. Francesco Signorelli is an Italian and French board-certified\nneurosurgeon. He was trained in neurosurgery at the University Hospital of Naples, Italy and was fellow in neurosurgery in\nLondon, Southampton, UK, and in Montreal, Canada. He spent\n15 years working as a consultant neurosurgeon at the Hospital\nfor Neurology and Neurosurgery in Lyon, France. He is currently\nprofessor and head of the Neurosurgical Division of the University\nHospital in Bari, Italy. His surgical practice and scientific activity cover the spectrum\nof neurosurgery, with more than 3000 interventions, more than 60 articles in peer-reviewed journals, and several books. His current major interests are vascular neurosurgery and brain and skull base tumors in adult and pediatric patients.",institutionString:'University of Bari Medical School "Aldo Moro"',position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"3",totalChapterViews:"0",totalEditedBooks:"4",institution:{name:"University of Bari Aldo Moro",institutionURL:null,country:{name:"Italy"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1148",title:"Neurosurgery",slug:"neurosurgery"}],chapters:[{id:"37120",title:"Trigeminocardiac Reflex in Neurosurgery - Current Knowledge and Prospects",doi:"10.5772/29607",slug:"the-trigeminocardiac-reflex-in-neurosurgery-current-knowledge-and-prospects",totalDownloads:3441,totalCrossrefCites:10,totalDimensionsCites:27,hasAltmetrics:0,abstract:null,signatures:"Amr Abdulazim, Martin N. Stienen, Pooyan Sadr-Eshkevari, Nora Prochnow, Nora Sandu, Benham Bohluli and Bernhard Schaller",downloadPdfUrl:"/chapter/pdf-download/37120",previewPdfUrl:"/chapter/pdf-preview/37120",authors:[{id:"78171",title:"Prof.",name:"Bernhard",surname:"Schaller",slug:"bernhard-schaller",fullName:"Bernhard Schaller"},{id:"78525",title:"Mr.",name:"Amr",surname:"Abdulazim",slug:"amr-abdulazim",fullName:"Amr Abdulazim"},{id:"78530",title:"Dr",name:"Pooyan",surname:"Sadr-Eshkevari",slug:"pooyan-sadr-eshkevari",fullName:"Pooyan Sadr-Eshkevari"},{id:"126039",title:"Dr.",name:"Martin",surname:"Stienen",slug:"martin-stienen",fullName:"Martin Stienen"},{id:"126040",title:"Dr.",name:"Nora",surname:"Prochnow",slug:"nora-prochnow",fullName:"Nora Prochnow"},{id:"126041",title:"Dr.",name:"Benham",surname:"Bohluli",slug:"benham-bohluli",fullName:"Benham Bohluli"}],corrections:null},{id:"37121",title:"Anesthesiologic Management for Awake Craniotomy",doi:"10.5772/30517",slug:"anesthesiologic-management-for-awake-craniotomy",totalDownloads:4046,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:null,signatures:"Roberto Zoppellari, Enrico Ferri and Manuela Pellegrini",downloadPdfUrl:"/chapter/pdf-download/37121",previewPdfUrl:"/chapter/pdf-preview/37121",authors:[{id:"82904",title:"Prof.",name:"Roberto",surname:"Zoppellari",slug:"roberto-zoppellari",fullName:"Roberto Zoppellari"},{id:"137256",title:"Dr.",name:"Enrico",surname:"Ferri",slug:"enrico-ferri",fullName:"Enrico Ferri"},{id:"137257",title:"Dr.",name:"Manuela",surname:"Pellegrini",slug:"manuela-pellegrini",fullName:"Manuela Pellegrini"}],corrections:null},{id:"37122",title:"Anaesthetic Management of Patients Undergoing Intraventricular Neuro-Endoscopic Procedures",doi:"10.5772/30681",slug:"anaesthesia-for-intracranial-neuro-endoscopic-procedures",totalDownloads:4977,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"A.F. Kalmar and F. Dewaele",downloadPdfUrl:"/chapter/pdf-download/37122",previewPdfUrl:"/chapter/pdf-preview/37122",authors:[{id:"83715",title:"Dr.",name:"Alain",surname:"Kalmar",slug:"alain-kalmar",fullName:"Alain Kalmar"},{id:"149904",title:"Mr.",name:"Frank",surname:"Dewaele",slug:"frank-dewaele",fullName:"Frank Dewaele"}],corrections:null},{id:"37123",title:"Neuro Critical Care",doi:"10.5772/31344",slug:"chapter-proposal-for-neurosurgery",totalDownloads:2270,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Mainak Majumdar",downloadPdfUrl:"/chapter/pdf-download/37123",previewPdfUrl:"/chapter/pdf-preview/37123",authors:[{id:"86678",title:"Dr.",name:"Mainak",surname:"Majumdar",slug:"mainak-majumdar",fullName:"Mainak Majumdar"}],corrections:null},{id:"37124",title:"Decompressive Craniectomy for Refractory Intracranial Hypertension",doi:"10.5772/29693",slug:"decompressive-craniectomy-for-refractory-intracranial-hypertension",totalDownloads:3326,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Michal Bar, Stefan Reguli and Radim Lipina",downloadPdfUrl:"/chapter/pdf-download/37124",previewPdfUrl:"/chapter/pdf-preview/37124",authors:[{id:"78966",title:"Dr.",name:"Michal",surname:"Bar",slug:"michal-bar",fullName:"Michal Bar"},{id:"86891",title:"Dr.",name:"Radim",surname:"Lipina",slug:"radim-lipina",fullName:"Radim Lipina"},{id:"123514",title:"Dr.",name:"Stefan",surname:"Reguli",slug:"stefan-reguli",fullName:"Stefan Reguli"}],corrections:null},{id:"37125",title:"Suboccipital Concentric Craniotomy as Variant for Posterior Cranial Fossa Surgery",doi:"10.5772/29329",slug:"suboccipital-concentric-craniotomy-as-variant-for-posterior-cranial-surgery",totalDownloads:3172,totalCrossrefCites:1,totalDimensionsCites:4,hasAltmetrics:0,abstract:null,signatures:"Abraham Ibarra-de la Torre, Fernando Rueda-Franco and Alfonso Marhx-Bracho",downloadPdfUrl:"/chapter/pdf-download/37125",previewPdfUrl:"/chapter/pdf-preview/37125",authors:[{id:"77314",title:"Dr.",name:"Abraham",surname:"Ibarra-De La Torre",slug:"abraham-ibarra-de-la-torre",fullName:"Abraham Ibarra-De La Torre"},{id:"86122",title:"Dr.",name:"Rueda-Franco",surname:"Fernando",slug:"rueda-franco-fernando",fullName:"Rueda-Franco Fernando"},{id:"86124",title:"Dr.",name:"Marhx-Bracho",surname:"Alfonso",slug:"marhx-bracho-alfonso",fullName:"Marhx-Bracho Alfonso"}],corrections:null},{id:"37126",title:"Diagnostic Evaluation of the Lesions of the Sellar and Parasellar Region",doi:"10.5772/31173",slug:"the-diagnostic-evaluation-of-the-lesions-of-the-sellar-and-parasellar-region",totalDownloads:10607,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Roberto Attanasio, Renato Cozzi, Giovanni Lasio and Regina Barbò",downloadPdfUrl:"/chapter/pdf-download/37126",previewPdfUrl:"/chapter/pdf-preview/37126",authors:[{id:"85910",title:"Dr.",name:"Roberto",surname:"Attanasio",slug:"roberto-attanasio",fullName:"Roberto Attanasio"}],corrections:null},{id:"37127",title:"Pineal Region Tumors",doi:"10.5772/30819",slug:"pineal-region-tumors",totalDownloads:5382,totalCrossrefCites:0,totalDimensionsCites:3,hasAltmetrics:0,abstract:null,signatures:"Paolo Cipriano Cecchi, Giuliano Giliberto, Angelo Musumeci and Andreas Schwarz",downloadPdfUrl:"/chapter/pdf-download/37127",previewPdfUrl:"/chapter/pdf-preview/37127",authors:[{id:"84401",title:"Dr.",name:"Paolo Cipriano",surname:"Cecchi",slug:"paolo-cipriano-cecchi",fullName:"Paolo Cipriano Cecchi"},{id:"86369",title:"Dr.",name:"Giuliano",surname:"Giliberto",slug:"giuliano-giliberto",fullName:"Giuliano Giliberto"},{id:"86370",title:"Dr.",name:"Angelo",surname:"Musumeci",slug:"angelo-musumeci",fullName:"Angelo Musumeci"},{id:"86784",title:"Dr.",name:"Andreas",surname:"Schwarz",slug:"andreas-schwarz",fullName:"Andreas Schwarz"}],corrections:null},{id:"37128",title:"Cerebral Aneurysms",doi:"10.5772/30511",slug:"cerebral-aneurysms-and-subarachinoid-hemorrhage",totalDownloads:2661,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Mohammad Jamous, Mohammad Barbarawi and Hytham El Oqaili",downloadPdfUrl:"/chapter/pdf-download/37128",previewPdfUrl:"/chapter/pdf-preview/37128",authors:[{id:"82874",title:"Dr.",name:"Mohammad",surname:"Jamous",slug:"mohammad-jamous",fullName:"Mohammad Jamous"}],corrections:null},{id:"37129",title:"Ruptured Cerebral Aneurysms: An Update",doi:"10.5772/29224",slug:"ruptured-cerebral-aneurysms-an-update",totalDownloads:3091,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Ming Zhong, Bing Zhao, Zequn Li and Xianxi Tan",downloadPdfUrl:"/chapter/pdf-download/37129",previewPdfUrl:"/chapter/pdf-preview/37129",authors:[{id:"76967",title:"Prof.",name:"Ming",surname:"Zhong",slug:"ming-zhong",fullName:"Ming Zhong"}],corrections:null},{id:"37130",title:"Surgical Management of Posterior Circulation Aneurysms: Defining the Role of Microsurgery in Contemporary Endovascular Era",doi:"10.5772/28669",slug:"surgical-management-of-posterior-circulation-aneurysms-defining-the-role-of-microsurgery-in-contempo",totalDownloads:3409,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Leon Lai and Michael Kerin Morgan",downloadPdfUrl:"/chapter/pdf-download/37130",previewPdfUrl:"/chapter/pdf-preview/37130",authors:[{id:"74913",title:"Dr.",name:"Leon",surname:"Lai",slug:"leon-lai",fullName:"Leon Lai"},{id:"85814",title:"Prof.",name:"Michael Kerin",surname:"Morgan",slug:"michael-kerin-morgan",fullName:"Michael Kerin Morgan"}],corrections:null},{id:"37131",title:"Skull Base Approaches for Vertebro-Basilar Aneurysms",doi:"10.5772/34932",slug:"skull-base-approaches-for-the-vertebro-basilar-aneurysms",totalDownloads:3280,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Renato J. Galzio, Danilo De Paulis and Francesco Di Cola",downloadPdfUrl:"/chapter/pdf-download/37131",previewPdfUrl:"/chapter/pdf-preview/37131",authors:[{id:"102268",title:"Prof.",name:"Renato",surname:"Galzio",slug:"renato-galzio",fullName:"Renato Galzio"},{id:"102283",title:"Dr.",name:"Francesco",surname:"Di Cola",slug:"francesco-di-cola",fullName:"Francesco Di Cola"},{id:"102287",title:"Dr.",name:"Danilo",surname:"De Paulis",slug:"danilo-de-paulis",fullName:"Danilo De Paulis"}],corrections:null},{id:"37132",title:"Endovascular Approaches to the Carotid Cavernous Sinus for Endovascular Treatment of Carotid Cavernous Fistulas and Hormone Sampling",doi:"10.5772/33917",slug:"approaches-to-the-carotid-cavernous-sinus",totalDownloads:2899,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Akira Kurata",downloadPdfUrl:"/chapter/pdf-download/37132",previewPdfUrl:"/chapter/pdf-preview/37132",authors:[{id:"97765",title:"Dr",name:null,surname:"Kurata",slug:"kurata",fullName:"Kurata"}],corrections:null},{id:"37133",title:"Craniovertebral Junction Chordomas",doi:"10.5772/30138",slug:"chordomas-of-tthe-craniocervical-junction",totalDownloads:2607,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Pratipal Kalsi and David Choi",downloadPdfUrl:"/chapter/pdf-download/37133",previewPdfUrl:"/chapter/pdf-preview/37133",authors:[{id:"81020",title:"Dr.",name:"Pratipal",surname:"Kalsi",slug:"pratipal-kalsi",fullName:"Pratipal Kalsi"},{id:"81046",title:"Mr.",name:"David",surname:"Choi",slug:"david-choi",fullName:"David Choi"}],corrections:null},{id:"37134",title:"Anatomical and Surgical Perspective to Approach Degenerative Disc Hernias",doi:"10.5772/29535",slug:"anatomical-and-surgical-perspective-to-approach-degenerative-disc-hernias",totalDownloads:3810,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"H. Selim Karabekir, Nuket Gocmen-Mas and Mete Edizer",downloadPdfUrl:"/chapter/pdf-download/37134",previewPdfUrl:"/chapter/pdf-preview/37134",authors:[{id:"25211",title:"Prof.",name:"Nuket",surname:"Gocmen Mas",slug:"nuket-gocmen-mas",fullName:"Nuket Gocmen Mas"},{id:"78266",title:"Prof.",name:"Hamit Selim",surname:"Karabekir",slug:"hamit-selim-karabekir",fullName:"Hamit Selim Karabekir"},{id:"78268",title:"Dr.",name:"Mete",surname:"Edizer",slug:"mete-edizer",fullName:"Mete Edizer"}],corrections:null},{id:"37135",title:"Balloon-Kyphoplasty for Vertebral Compression Fractures",doi:"10.5772/28935",slug:"balloon-kyphoplasty-for-vertebral-compression-fractures",totalDownloads:3672,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Luca Arpino and Pierpaolo Nina",downloadPdfUrl:"/chapter/pdf-download/37135",previewPdfUrl:"/chapter/pdf-preview/37135",authors:[{id:"75917",title:"Dr.",name:"Luca",surname:"Arpino",slug:"luca-arpino",fullName:"Luca Arpino"},{id:"99739",title:"Dr.",name:"Pierpaolo",surname:"Nina",slug:"pierpaolo-nina",fullName:"Pierpaolo Nina"}],corrections:null},{id:"37136",title:"Cognitive and Behavioural Changes After Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease",doi:"10.5772/32005",slug:"cognitive-and-behavioural-changes-after-deep-brain-stimulation-of-the-subthalamic-nucleus-in-parkins",totalDownloads:2717,totalCrossrefCites:1,totalDimensionsCites:3,hasAltmetrics:0,abstract:null,signatures:"Antonio Daniele, Pietro Spinelli and Chiara Piccininni",downloadPdfUrl:"/chapter/pdf-download/37136",previewPdfUrl:"/chapter/pdf-preview/37136",authors:[{id:"89728",title:"Dr",name:"Antonio",surname:"Daniele",slug:"antonio-daniele",fullName:"Antonio Daniele"}],corrections:null},{id:"37137",title:"Targeting the Subthalamic Nucleus for Deep Brain Stimulation in Parkinson Disease: The Impact of High Field Strength MRI",doi:"10.5772/31794",slug:"advent-of-3-tesla-mri-for-planning-functional-neurosurgery-first-comparative-study",totalDownloads:2554,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Dirk Winkler, Marc Tittgemeyer, Karl Strecker, Axel Goldammer, Jochen Helm, Johannes Schwarz and Jürgen Meixensberger",downloadPdfUrl:"/chapter/pdf-download/37137",previewPdfUrl:"/chapter/pdf-preview/37137",authors:[{id:"88690",title:"Dr",name:null,surname:"Winkler",slug:"winkler",fullName:"Winkler"}],corrections:null},{id:"37138",title:"An Assistive Surgical MRI Compatible Robot - First Prototype with Field Tests",doi:"10.5772/29557",slug:"an-assistive-surgical-mri-compatible-robot-first-prototype-with-field-tests",totalDownloads:2414,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Tapio Heikkilä, Sanna Yrjänä, Pekka Kilpeläinen, John Koivukangas and Mikko Sallinen",downloadPdfUrl:"/chapter/pdf-download/37138",previewPdfUrl:"/chapter/pdf-preview/37138",authors:[{id:"5451",title:"Dr.",name:"Mikko",surname:"Sallinen",slug:"mikko-sallinen",fullName:"Mikko Sallinen"},{id:"78356",title:"Dr.",name:"Tapio",surname:"Heikkila",slug:"tapio-heikkila",fullName:"Tapio Heikkila"},{id:"123508",title:"Dr.",name:"Sanna",surname:"Yrjänä",slug:"sanna-yrjana",fullName:"Sanna Yrjänä"},{id:"123509",title:"Mr.",name:"Pekka",surname:"Kilpelainen",slug:"pekka-kilpelainen",fullName:"Pekka Kilpelainen"},{id:"123510",title:"Prof.",name:"John",surname:"Koivukangas",slug:"john-koivukangas",fullName:"John Koivukangas"}],corrections:null},{id:"37139",title:"Robotic Catheter Operating Systems for Endovascular Neurosurgery",doi:"10.5772/29907",slug:"robotic-catheter-operating-systems-for-endovascular-neurosurgery",totalDownloads:2691,totalCrossrefCites:2,totalDimensionsCites:2,hasAltmetrics:0,abstract:null,signatures:"Shuxiang Guo, Jian Guo, Nan Xiao and Takashi Tamiya",downloadPdfUrl:"/chapter/pdf-download/37139",previewPdfUrl:"/chapter/pdf-preview/37139",authors:[{id:"14601",title:"Prof.",name:"Shuxiang",surname:"Guo",slug:"shuxiang-guo",fullName:"Shuxiang Guo"},{id:"79846",title:"Dr.",name:"Jian",surname:"Guo",slug:"jian-guo",fullName:"Jian Guo"},{id:"147755",title:"Dr.",name:"Nan",surname:"Xiao",slug:"nan-xiao",fullName:"Nan Xiao"},{id:"147756",title:"Prof.",name:"Takashi",surname:"Tamiya",slug:"takashi-tamiya",fullName:"Takashi Tamiya"}],corrections:null},{id:"37140",title:"The Role of Neural Stem Cells in Neurorestoration",doi:"10.5772/29754",slug:"neural-stem-cells-in-the-adult-human-brain",totalDownloads:1883,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"E.O. Vik-Mo, A. Fayzullin, M.C. Moe, H. Olstorn and I.A. Langmoen",downloadPdfUrl:"/chapter/pdf-download/37140",previewPdfUrl:"/chapter/pdf-preview/37140",authors:[{id:"79180",title:"Dr.",name:"Morten",surname:"Moe",slug:"morten-moe",fullName:"Morten Moe"},{id:"85741",title:"Ms.",name:"Rebecca",surname:"Frøen",slug:"rebecca-froen",fullName:"Rebecca Frøen"},{id:"86937",title:"Prof.",name:"Iver A.",surname:"Langmoen",slug:"iver-a.-langmoen",fullName:"Iver A. Langmoen"},{id:"87159",title:"MSc.",name:"Erik O.",surname:"Johnsen",slug:"erik-o.-johnsen",fullName:"Erik O. Johnsen"},{id:"87161",title:"Dr.",name:"Einar",surname:"Vik-Mo",slug:"einar-vik-mo",fullName:"Einar Vik-Mo"}],corrections:null},{id:"37141",title:"Hemostatic Agents in Neurosurgery",doi:"10.5772/31319",slug:"topical-hemostatic-agents-and-neurosurgery",totalDownloads:12110,totalCrossrefCites:2,totalDimensionsCites:5,hasAltmetrics:0,abstract:null,signatures:"F. Lapierre, S. D'Houtaud and M. Wager",downloadPdfUrl:"/chapter/pdf-download/37141",previewPdfUrl:"/chapter/pdf-preview/37141",authors:[{id:"86601",title:"Dr.",name:"Françoise",surname:"Lapierre",slug:"francoise-lapierre",fullName:"Françoise Lapierre"}],corrections:null},{id:"37142",title:"Use of Physical Restraints in Neurosurgery: Guide for a Good Practice",doi:"10.5772/28921",slug:"use-of-physical-restraints-in-neurosurgery-guide-for-a-good-practice",totalDownloads:4128,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Ayten Demir Zencirci",downloadPdfUrl:"/chapter/pdf-download/37142",previewPdfUrl:"/chapter/pdf-preview/37142",authors:[{id:"75863",title:"Associate Prof.",name:"Ayten",surname:"Demir Zencirci",slug:"ayten-demir-zencirci",fullName:"Ayten Demir Zencirci"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"5234",title:"Trauma, Tumors, Spine, Functional Neurosurgery",subtitle:null,isOpenForSubmission:!1,hash:"58640694ad7cbb2e82d217935b12f243",slug:"from-bench-to-bedside-trauma-tumors-spine-functional-neurosurgery",bookSignature:"Francesco Signorelli",coverURL:"https://cdn.intechopen.com/books/images_new/5234.jpg",editedByType:"Edited by",editors:[{id:"74494",title:"Dr.",name:"Francesco",surname:"Signorelli",slug:"francesco-signorelli",fullName:"Francesco Signorelli"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3548",title:"Functional Brain Mapping and the Endeavor to Understand the Working Brain",subtitle:null,isOpenForSubmission:!1,hash:"e37aa76c89bf5fe53740593a6c9668e1",slug:"functional-brain-mapping-and-the-endeavor-to-understand-the-working-brain",bookSignature:"Francesco Signorelli and Domenico Chirchiglia",coverURL:"https://cdn.intechopen.com/books/images_new/3548.jpg",editedByType:"Edited by",editors:[{id:"74494",title:"Dr.",name:"Francesco",surname:"Signorelli",slug:"francesco-signorelli",fullName:"Francesco Signorelli"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8729",title:"Neurofibromatosis",subtitle:"Current Trends and Future Directions",isOpenForSubmission:!1,hash:"d1e955bf58e8cf955270cefb3bdd10bd",slug:"neurofibromatosis-current-trends-and-future-directions",bookSignature:"Francesco Signorelli and Raffaella Messina",coverURL:"https://cdn.intechopen.com/books/images_new/8729.jpg",editedByType:"Edited by",editors:[{id:"74494",title:"Dr.",name:"Francesco",surname:"Signorelli",slug:"francesco-signorelli",fullName:"Francesco Signorelli"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1244",title:"Spine Surgery",subtitle:null,isOpenForSubmission:!1,hash:"9ea5cece2b7ea45907a75de2cc8955f9",slug:"spine-surgery",bookSignature:"Kook Jin Chung",coverURL:"https://cdn.intechopen.com/books/images_new/1244.jpg",editedByType:"Edited by",editors:[{id:"113935",title:"Dr.",name:"Kook Jin",surname:"Chung",slug:"kook-jin-chung",fullName:"Kook Jin Chung"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"690",title:"Gamma Knife Radiosurgery",subtitle:null,isOpenForSubmission:!1,hash:"adb45f5be8b65b622ee009c0e5ebe34c",slug:"gamma-knife-radiosurgery",bookSignature:"David Mathieu",coverURL:"https://cdn.intechopen.com/books/images_new/690.jpg",editedByType:"Edited by",editors:[{id:"76960",title:"Dr.",name:"David",surname:"Mathieu",slug:"david-mathieu",fullName:"David Mathieu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6374",title:"Hydrocephalus",subtitle:"Water on the Brain",isOpenForSubmission:!1,hash:"b431d113b9d7fca7e67c463f0970ed04",slug:"hydrocephalus-water-on-the-brain",bookSignature:"Bora Gürer",coverURL:"https://cdn.intechopen.com/books/images_new/6374.jpg",editedByType:"Edited by",editors:[{id:"95341",title:"Prof.",name:"Bora",surname:"Gürer",slug:"bora-gurer",fullName:"Bora Gürer"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10723",title:"Brachial Plexus Injury",subtitle:"New Techniques and Ideas",isOpenForSubmission:!1,hash:"94c1a38f1ee7a078ee6ec640360c39f2",slug:"brachial-plexus-injury-new-techniques-and-ideas",bookSignature:"Jörg Bahm",coverURL:"https://cdn.intechopen.com/books/images_new/10723.jpg",editedByType:"Edited by",editors:[{id:"78207",title:"Prof.",name:"Jörg",surname:"Bahm",slug:"jorg-bahm",fullName:"Jörg Bahm"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10537",title:"Frontiers in Clinical Neurosurgery",subtitle:null,isOpenForSubmission:!1,hash:"908c7edd9fcb3cbafbf42d30232db9a0",slug:"frontiers-in-clinical-neurosurgery",bookSignature:"Xianli Lv, Guihuai Wang, James Wang and Zhongxue Wu",coverURL:"https://cdn.intechopen.com/books/images_new/10537.jpg",editedByType:"Edited by",editors:[{id:"153155",title:"Dr.",name:"Xianli",surname:"Lv",slug:"xianli-lv",fullName:"Xianli Lv"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8339",title:"Neurosurgical Procedures",subtitle:"Innovative Approaches",isOpenForSubmission:!1,hash:"32ead2c9d075e8762721f52b7ea22b51",slug:"neurosurgical-procedures-innovative-approaches",bookSignature:"Alba Scerrati and Pasquale De Bonis",coverURL:"https://cdn.intechopen.com/books/images_new/8339.jpg",editedByType:"Edited by",editors:[{id:"182614",title:"Dr.",name:"Alba",surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],ofsBooks:[]},correction:{item:{id:"79356",slug:"corrigendum-pregnancy-and-graves-disease",title:"Corrigendum: Pregnancy and Graves’ Disease",doi:null,correctionPDFUrl:"https://cdn.intechopen.com/pdfs/79786.pdf",downloadPdfUrl:"/chapter/pdf-download/79786",previewPdfUrl:"/chapter/pdf-preview/79786",totalDownloads:null,totalCrossrefCites:null,bibtexUrl:"/chapter/bibtex/79786",risUrl:"/chapter/ris/79786",chapter:{id:"75306",slug:"pregnancy-in-women-with-graves-disease-focus-on-fetal-surveillance",signatures:"Anca Maria Panaitescu",dateSubmitted:"December 16th 2020",dateReviewed:"January 27th 2021",datePrePublished:"February 18th 2021",datePublished:"December 1st 2021",book:{id:"10312",title:"Graves' Disease",subtitle:null,fullTitle:"Graves' Disease",slug:"graves-disease",publishedDate:"December 1st 2021",bookSignature:"Robert Gensure",coverURL:"https://cdn.intechopen.com/books/images_new/10312.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"16515",title:"Dr.",name:"Robert",middleName:null,surname:"Gensure",slug:"robert-gensure",fullName:"Robert Gensure"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"251062",title:"Ph.D.",name:"Anca",middleName:null,surname:"Panaitescu",fullName:"Anca Panaitescu",slug:"anca-panaitescu",email:"panaitescu.anca@yahoo.com",position:null,institution:null}]}},chapter:{id:"75306",slug:"pregnancy-in-women-with-graves-disease-focus-on-fetal-surveillance",signatures:"Anca Maria Panaitescu",dateSubmitted:"December 16th 2020",dateReviewed:"January 27th 2021",datePrePublished:"February 18th 2021",datePublished:"December 1st 2021",book:{id:"10312",title:"Graves' Disease",subtitle:null,fullTitle:"Graves' Disease",slug:"graves-disease",publishedDate:"December 1st 2021",bookSignature:"Robert Gensure",coverURL:"https://cdn.intechopen.com/books/images_new/10312.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"16515",title:"Dr.",name:"Robert",middleName:null,surname:"Gensure",slug:"robert-gensure",fullName:"Robert Gensure"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"251062",title:"Ph.D.",name:"Anca",middleName:null,surname:"Panaitescu",fullName:"Anca Panaitescu",slug:"anca-panaitescu",email:"panaitescu.anca@yahoo.com",position:null,institution:null}]},book:{id:"10312",title:"Graves' Disease",subtitle:null,fullTitle:"Graves' Disease",slug:"graves-disease",publishedDate:"December 1st 2021",bookSignature:"Robert Gensure",coverURL:"https://cdn.intechopen.com/books/images_new/10312.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"16515",title:"Dr.",name:"Robert",middleName:null,surname:"Gensure",slug:"robert-gensure",fullName:"Robert Gensure"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},ofsBook:{item:{type:"book",id:"12341",leadTitle:null,title:"Tonsils and Adenoids",subtitle:null,reviewType:"peer-reviewed",abstract:"This book will be a self-contained collection of scholarly papers targeting an audience of practicing researchers, academics, PhD students and other scientists. The contents of the book will be written by multiple authors and edited by experts in the field.",isbn:null,printIsbn:null,pdfIsbn:null,doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"46beabb56a294b711d62826263e99b68",bookSignature:"",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/12341.jpg",keywords:null,numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"May 10th 2022",dateEndSecondStepPublish:"May 31st 2022",dateEndThirdStepPublish:"July 30th 2022",dateEndFourthStepPublish:"October 18th 2022",dateEndFifthStepPublish:"December 17th 2022",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"3 months",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:1,editedByType:null,kuFlag:!1,biosketch:null,coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"16",title:"Medicine",slug:"medicine"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:null},relatedBooks:[{type:"book",id:"6550",title:"Cohort Studies in Health Sciences",subtitle:null,isOpenForSubmission:!1,hash:"01df5aba4fff1a84b37a2fdafa809660",slug:"cohort-studies-in-health-sciences",bookSignature:"R. Mauricio Barría",coverURL:"https://cdn.intechopen.com/books/images_new/6550.jpg",editedByType:"Edited by",editors:[{id:"88861",title:"Dr.",name:"R. Mauricio",surname:"Barría",slug:"r.-mauricio-barria",fullName:"R. Mauricio Barría"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9500",title:"Recent Advances in Bone Tumours and Osteoarthritis",subtitle:null,isOpenForSubmission:!1,hash:"ea4ec0d6ee01b88e264178886e3210ed",slug:"recent-advances-in-bone-tumours-and-osteoarthritis",bookSignature:"Hiran Amarasekera",coverURL:"https://cdn.intechopen.com/books/images_new/9500.jpg",editedByType:"Edited by",editors:[{id:"67634",title:"Dr.",name:"Hiran",surname:"Amarasekera",slug:"hiran-amarasekera",fullName:"Hiran Amarasekera"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2270",title:"Fourier Transform",subtitle:"Materials Analysis",isOpenForSubmission:!1,hash:"5e094b066da527193e878e160b4772af",slug:"fourier-transform-materials-analysis",bookSignature:"Salih Mohammed Salih",coverURL:"https://cdn.intechopen.com/books/images_new/2270.jpg",editedByType:"Edited by",editors:[{id:"111691",title:"Dr.Ing.",name:"Salih",surname:"Salih",slug:"salih-salih",fullName:"Salih Salih"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"117",title:"Artificial Neural Networks",subtitle:"Methodological Advances and Biomedical Applications",isOpenForSubmission:!1,hash:null,slug:"artificial-neural-networks-methodological-advances-and-biomedical-applications",bookSignature:"Kenji Suzuki",coverURL:"https://cdn.intechopen.com/books/images_new/117.jpg",editedByType:"Edited by",editors:[{id:"3095",title:"Prof.",name:"Kenji",surname:"Suzuki",slug:"kenji-suzuki",fullName:"Kenji Suzuki"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"872",title:"Organic Pollutants Ten Years After the Stockholm Convention",subtitle:"Environmental and Analytical Update",isOpenForSubmission:!1,hash:"f01dc7077e1d23f3d8f5454985cafa0a",slug:"organic-pollutants-ten-years-after-the-stockholm-convention-environmental-and-analytical-update",bookSignature:"Tomasz Puzyn and Aleksandra Mostrag-Szlichtyng",coverURL:"https://cdn.intechopen.com/books/images_new/872.jpg",editedByType:"Edited by",editors:[{id:"84887",title:"Dr.",name:"Tomasz",surname:"Puzyn",slug:"tomasz-puzyn",fullName:"Tomasz Puzyn"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"23621",title:"Application of Low-Temperature Plasma Processes for Biomaterials",doi:"10.5772/25035",slug:"application-of-low-temperature-plasma-processes-for-biomaterials",body:null,keywords:null,chapterPDFUrl:"https://cdn.intechopen.com/pdfs/23621.pdf",chapterXML:null,downloadPdfUrl:"/chapter/pdf-download/23621",previewPdfUrl:"/chapter/pdf-preview/23621",totalDownloads:5027,totalViews:136,totalCrossrefCites:1,totalDimensionsCites:2,totalAltmetricsMentions:0,introChapter:null,impactScore:1,impactScorePercentile:53,impactScoreQuartile:3,hasAltmetrics:0,dateSubmitted:"December 20th 2010",dateReviewed:"May 6th 2011",datePrePublished:null,datePublished:"November 16th 2011",dateFinished:null,readingETA:"0",abstract:null,reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/23621",risUrl:"/chapter/ris/23621",book:{id:"1487",slug:"biomaterials-applications-for-nanomedicine"},signatures:"Michael Schlosser Uwe Walschus, Karsten Schröder, Birgit Finke, Barbara Nebe, Jürgen Meichsner, Rainer Hippler, Rainer Bader and Andreas Podbielski",authors:[{id:"48929",title:"Dr.",name:"Birgit",middleName:null,surname:"Finke",fullName:"Birgit Finke",slug:"birgit-finke",email:"finke@inp-greifswald.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Leibniz Institute for Plasma Science and Technology",institutionURL:null,country:{name:"Germany"}}},{id:"48930",title:"Dr.",name:"Barbara",middleName:null,surname:"Nebe",fullName:"Barbara Nebe",slug:"barbara-nebe",email:"barbara.nebe@med.uni-rostock.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Universitätsmedizin Rostock",institutionURL:null,country:{name:"Germany"}}},{id:"48934",title:"Dr.",name:"Karsten",middleName:null,surname:"Schröder",fullName:"Karsten Schröder",slug:"karsten-schroder",email:"schroeder@inp-greifswald.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Leibniz Institute for Plasma Science and Technology",institutionURL:null,country:{name:"Germany"}}},{id:"61229",title:"Dr.",name:"Michael",middleName:null,surname:"Schlosser",fullName:"Michael Schlosser",slug:"michael-schlosser",email:"schlosse@uni-greifswald.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"University of Greifswald",institutionURL:null,country:{name:"Germany"}}},{id:"61240",title:"Mr.",name:"Uwe",middleName:null,surname:"Walschus",fullName:"Uwe Walschus",slug:"uwe-walschus",email:"uwe.walschus@uni-greifswald.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"University of Greifswald",institutionURL:null,country:{name:"Germany"}}},{id:"61241",title:"Prof.",name:"Rainer",middleName:null,surname:"Bader",fullName:"Rainer Bader",slug:"rainer-bader",email:"rainer.bader@med.uni-rostock.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"University of Rostock",institutionURL:null,country:{name:"Germany"}}},{id:"61242",title:"Prof.",name:"Andreas",middleName:null,surname:"Podbielski",fullName:"Andreas Podbielski",slug:"andreas-podbielski",email:"andreas.podbielski@med.uni-rostock.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Universitätsmedizin Rostock",institutionURL:null,country:{name:"Germany"}}},{id:"61243",title:"Prof.",name:"Rainer",middleName:null,surname:"Hippler",fullName:"Rainer Hippler",slug:"rainer-hippler",email:"hippler@physik.uni-greifswald.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"University of Greifswald",institutionURL:null,country:{name:"Germany"}}},{id:"61244",title:"Dr.",name:"Jürgen",middleName:null,surname:"Meichsner",fullName:"Jürgen Meichsner",slug:"jurgen-meichsner",email:"meichsner@physik.uni-greifswald.de",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"University of Greifswald",institutionURL:null,country:{name:"Germany"}}}],sections:null,chapterReferences:null,footnotes:null,contributors:null,corrections:null},book:{id:"1487",type:"book",title:"Biomaterials",subtitle:"Applications for Nanomedicine",fullTitle:"Biomaterials Applications for Nanomedicine",slug:"biomaterials-applications-for-nanomedicine",publishedDate:"November 16th 2011",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/1487.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:null,printIsbn:"978-953-307-661-4",pdfIsbn:"978-953-51-4399-4",reviewType:"peer-reviewed",numberOfWosCitations:410,isAvailableForWebshopOrdering:!0,editors:[{id:"64447",title:"Prof.",name:"Rosario",middleName:null,surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"916"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"23616",type:"chapter",title:"Bioactive Ceramics as Bone Morphogenetic Proteins Carriers",slug:"bioactive-ceramics-as-bone-morphogenetic-proteins-carriers",totalDownloads:2828,totalCrossrefCites:0,signatures:"Sayed Mahmood Rabiee",reviewType:"peer-reviewed",authors:[{id:"50304",title:"Prof.",name:"Sayed Mahmood",middleName:null,surname:"Rabiee",fullName:"Sayed Mahmood Rabiee",slug:"sayed-mahmood-rabiee"}]},{id:"23617",type:"chapter",title:"Collagen- vs. Gelatine-Based Biomaterials and Their Biocompatibility: Review and Perspectives",slug:"collagen-vs-gelatine-based-biomaterials-and-their-biocompatibility-review-and-perspectives",totalDownloads:9469,totalCrossrefCites:63,signatures:"Selestina Gorgieva and Vanja Kokol",reviewType:"peer-reviewed",authors:[{id:"55577",title:"Prof.",name:"Vanja",middleName:null,surname:"Kokol",fullName:"Vanja Kokol",slug:"vanja-kokol"},{id:"61285",title:"BSc",name:"Selestina",middleName:null,surname:"Gorgieva",fullName:"Selestina Gorgieva",slug:"selestina-gorgieva"}]},{id:"23618",type:"chapter",title:"Hydrogel Scaffolds Contribute to the Osteogenesis and Chondrogenesis in the Small Osteochongral Defects",slug:"hydrogel-scaffolds-contribute-to-the-osteogenesis-and-chondrogenesis-in-the-small-osteochongral-defe",totalDownloads:2266,totalCrossrefCites:1,signatures:"Miroslav Petrtyl, Jaroslav Lisal, Ladislav Senolt, Zdenek Bastl, Zdenek Krulis, Marketa Polanska, Hana Hulejova, Pavel Cerny and Jana Danesova",reviewType:"peer-reviewed",authors:[{id:"60810",title:"Prof.",name:"Miroslav",middleName:null,surname:"Petrtyl",fullName:"Miroslav Petrtyl",slug:"miroslav-petrtyl"},{id:"60819",title:"Dr.",name:"Jaroslav",middleName:null,surname:"Lisal",fullName:"Jaroslav Lisal",slug:"jaroslav-lisal"},{id:"60844",title:"Dr.",name:"Ladislav",middleName:null,surname:"Šenolt",fullName:"Ladislav Šenolt",slug:"ladislav-senolt"},{id:"60845",title:"Dr.",name:"Zdenek",middleName:null,surname:"Bastl",fullName:"Zdenek Bastl",slug:"zdenek-bastl"},{id:"60846",title:"Dr.",name:"Zdenek",middleName:null,surname:"Krulis",fullName:"Zdenek Krulis",slug:"zdenek-krulis"},{id:"60847",title:"Dr.",name:"Marketa",middleName:null,surname:"Polanska",fullName:"Marketa Polanska",slug:"marketa-polanska"},{id:"60848",title:"Dr.",name:"Hana",middleName:null,surname:"Hulejova",fullName:"Hana Hulejova",slug:"hana-hulejova"},{id:"60849",title:"MSc.",name:"Pavel",middleName:null,surname:"Cerny",fullName:"Pavel Cerny",slug:"pavel-cerny"},{id:"60850",title:"Dr.",name:"Jana",middleName:null,surname:"Danesova",fullName:"Jana Danesova",slug:"jana-danesova"}]},{id:"23619",type:"chapter",title:"Development and Applications of Varieties of Bioactive Glass Compositions in Dental Surgery, Third Generation Tissue Engineering, Orthopaedic Surgery and as Drug Delivery System",slug:"development-and-applications-of-varieties-of-bioactive-glass-compositions-in-dental-surgery-third-ge",totalDownloads:3814,totalCrossrefCites:1,signatures:"Samit Kumar Nandi, Biswanath Kundu and Someswar Datta",reviewType:"peer-reviewed",authors:[{id:"60514",title:"Dr.",name:"Samit",middleName:null,surname:"Nandi",fullName:"Samit Nandi",slug:"samit-nandi"},{id:"61615",title:"Mr.",name:"Biswanath",middleName:null,surname:"Kundu",fullName:"Biswanath Kundu",slug:"biswanath-kundu"},{id:"61616",title:"Mr.",name:"Someswar",middleName:null,surname:"Datta",fullName:"Someswar Datta",slug:"someswar-datta"}]},{id:"23620",type:"chapter",title:"Elasticity of Spider Dragline Silks Viewed as Nematics: Yielding Induced by Isotropic-Nematic Phase Transition",slug:"elasticity-of-spider-dragline-silks-viewed-as-nematics-yielding-induced-by-isotropic-nematic-phase-t",totalDownloads:1812,totalCrossrefCites:0,signatures:"Linying Cui, Fei Liu and Zhong-Can Ou-Yang",reviewType:"peer-reviewed",authors:[{id:"51812",title:"Ms.",name:"Linying",middleName:null,surname:"Cui",fullName:"Linying Cui",slug:"linying-cui"},{id:"51815",title:"Dr.",name:"Zhong-Can",middleName:null,surname:"Ou-Yang",fullName:"Zhong-Can Ou-Yang",slug:"zhong-can-ou-yang"},{id:"52000",title:"Dr.",name:"Fei",middleName:null,surname:"Liu",fullName:"Fei Liu",slug:"fei-liu"}]},{id:"23621",type:"chapter",title:"Application of Low-Temperature Plasma Processes for Biomaterials",slug:"application-of-low-temperature-plasma-processes-for-biomaterials",totalDownloads:5027,totalCrossrefCites:1,signatures:"Michael Schlosser Uwe Walschus, Karsten Schröder, Birgit Finke, Barbara Nebe, Jürgen Meichsner, Rainer Hippler, Rainer Bader and Andreas Podbielski",reviewType:"peer-reviewed",authors:[{id:"48929",title:"Dr.",name:"Birgit",middleName:null,surname:"Finke",fullName:"Birgit Finke",slug:"birgit-finke"},{id:"48930",title:"Dr.",name:"Barbara",middleName:null,surname:"Nebe",fullName:"Barbara Nebe",slug:"barbara-nebe"},{id:"48934",title:"Dr.",name:"Karsten",middleName:null,surname:"Schröder",fullName:"Karsten Schröder",slug:"karsten-schroder"},{id:"61229",title:"Dr.",name:"Michael",middleName:null,surname:"Schlosser",fullName:"Michael Schlosser",slug:"michael-schlosser"},{id:"61240",title:"Mr.",name:"Uwe",middleName:null,surname:"Walschus",fullName:"Uwe Walschus",slug:"uwe-walschus"},{id:"61241",title:"Prof.",name:"Rainer",middleName:null,surname:"Bader",fullName:"Rainer Bader",slug:"rainer-bader"},{id:"61242",title:"Prof.",name:"Andreas",middleName:null,surname:"Podbielski",fullName:"Andreas Podbielski",slug:"andreas-podbielski"},{id:"61243",title:"Prof.",name:"Rainer",middleName:null,surname:"Hippler",fullName:"Rainer Hippler",slug:"rainer-hippler"},{id:"61244",title:"Dr.",name:"Jürgen",middleName:null,surname:"Meichsner",fullName:"Jürgen Meichsner",slug:"jurgen-meichsner"}]},{id:"23622",type:"chapter",title:"δ-Free FoF1-ATPase, Nanomachine and Biosensor",slug:"-free-fof1-atpase-nanomachine-and-biosensor",totalDownloads:2185,totalCrossrefCites:0,signatures:"Jia-Chang Yue, Yao-Gen Shu, Pei-Rong Wang and Xu Zhang",reviewType:"peer-reviewed",authors:[{id:"50443",title:"Prof.",name:"Jiachang",middleName:null,surname:"Yue",fullName:"Jiachang Yue",slug:"jiachang-yue"},{id:"61166",title:"Prof.",name:"Yao-Gen",middleName:null,surname:"Shu",fullName:"Yao-Gen Shu",slug:"yao-gen-shu"},{id:"61167",title:"Dr.",name:"Pei-Rong",middleName:null,surname:"Wang",fullName:"Pei-Rong Wang",slug:"pei-rong-wang"},{id:"61168",title:"Dr.",name:"Xu",middleName:null,surname:"Zhang",fullName:"Xu Zhang",slug:"xu-zhang"}]},{id:"23623",type:"chapter",title:"PLGA-Alendronate Conjugate as a New Biomaterial to Produce Osteotropic Drug Nanocarriers",slug:"plga-alendronate-conjugate-as-a-new-biomaterial-to-produce-osteotropic-drug-nanocarriers",totalDownloads:4058,totalCrossrefCites:1,signatures:"Rosario Pignatello",reviewType:"peer-reviewed",authors:[{id:"64447",title:"Prof.",name:"Rosario",middleName:null,surname:"Pignatello",fullName:"Rosario Pignatello",slug:"rosario-pignatello"}]},{id:"23624",type:"chapter",title:"Complete Healing of Severe Experimental Osseous Infections Using a Calcium-Deficient Apatite as a Drug-Delivery System",slug:"complete-healing-of-severe-experimental-osseous-infections-using-a-calcium-deficient-apatite-as-a-dr",totalDownloads:2286,totalCrossrefCites:1,signatures:"G. Amador Del Valle, H. Gautier, A. Gaudin, V. Le Mabecque, A.F. Miegeville, J.M. Bouler, J. Caillon, P. Weiss, G. Potel and C. Jacqueline",reviewType:"peer-reviewed",authors:[{id:"61659",title:"Dr.",name:"Gilles",middleName:null,surname:"Amador",fullName:"Gilles Amador",slug:"gilles-amador"},{id:"62605",title:"Dr.",name:"Hélène",middleName:null,surname:"Gautier",fullName:"Hélène Gautier",slug:"helene-gautier"},{id:"62606",title:"Dr.",name:"Alexis",middleName:null,surname:"Gaudin",fullName:"Alexis Gaudin",slug:"alexis-gaudin"},{id:"62607",title:"Ms.",name:"Virginie",middleName:null,surname:"Le Mabecque",fullName:"Virginie Le Mabecque",slug:"virginie-le-mabecque"},{id:"62608",title:"Mrs.",name:"Anne-Françoise",middleName:null,surname:"Miegeville",fullName:"Anne-Françoise Miegeville",slug:"anne-francoise-miegeville"},{id:"62609",title:"Prof.",name:"Jean-Michel",middleName:null,surname:"Bouler",fullName:"Jean-Michel Bouler",slug:"jean-michel-bouler"},{id:"62610",title:"Dr.",name:"Jocelyne",middleName:null,surname:"Caillon",fullName:"Jocelyne Caillon",slug:"jocelyne-caillon"},{id:"62611",title:"Prof.",name:"Pierre",middleName:null,surname:"Weiss",fullName:"Pierre Weiss",slug:"pierre-weiss"},{id:"62612",title:"Prof.",name:"Gilles",middleName:null,surname:"Potel",fullName:"Gilles Potel",slug:"gilles-potel"},{id:"62614",title:"Dr.",name:"Cedric",middleName:null,surname:"Jacqueline",fullName:"Cedric Jacqueline",slug:"cedric-jacqueline"}]},{id:"23625",type:"chapter",title:"Nanocrystalline Diamond Films: Applications and Advances in Nanomedicine",slug:"nanocrystalline-diamond-films-applications-and-advances-in-nanomedicine",totalDownloads:3473,totalCrossrefCites:1,signatures:"Ying-Chieh Chen, Don-Ching Lee and Ing-Ming Chiu",reviewType:"peer-reviewed",authors:[{id:"58229",title:"Dr.",name:"Ing-Ming",middleName:null,surname:"Chiu",fullName:"Ing-Ming Chiu",slug:"ing-ming-chiu"},{id:"61150",title:"Dr.",name:"Ying-Chieh",middleName:null,surname:"Chen",fullName:"Ying-Chieh Chen",slug:"ying-chieh-chen"},{id:"61151",title:"Mr.",name:"Don-Ching",middleName:null,surname:"Lee",fullName:"Don-Ching Lee",slug:"don-ching-lee"}]},{id:"23626",type:"chapter",title:"Transfection of Bone Cells In Vivo Using HA-Ceramic Particles - Histological Study",slug:"transfection-of-bone-cells-in-vivo-using-ha-ceramic-particles-histological-study",totalDownloads:1949,totalCrossrefCites:0,signatures:"Patrick Frayssinet and Nicole Rouquet",reviewType:"peer-reviewed",authors:[{id:"50905",title:"Dr.",name:"Patrick",middleName:null,surname:"Frayssinet",fullName:"Patrick Frayssinet",slug:"patrick-frayssinet"},{id:"60751",title:"Prof.",name:"Nicole",middleName:null,surname:"Rouquet",fullName:"Nicole Rouquet",slug:"nicole-rouquet"}]},{id:"23627",type:"chapter",title:"Magnetite Nanoparticles for Cell Lysis Implanted Into Bone - Histological and TEM Study",slug:"magnetite-nanoparticles-for-cell-lysis-implanted-into-bone-histological-and-tem-study",totalDownloads:2188,totalCrossrefCites:1,signatures:"Patrick Frayssinet, Didier Mathon, Marylène Combacau and Nicole Rouquet",reviewType:"peer-reviewed",authors:[{id:"50905",title:"Dr.",name:"Patrick",middleName:null,surname:"Frayssinet",fullName:"Patrick Frayssinet",slug:"patrick-frayssinet"},{id:"60751",title:"Prof.",name:"Nicole",middleName:null,surname:"Rouquet",fullName:"Nicole Rouquet",slug:"nicole-rouquet"},{id:"60749",title:"Mrs.",name:"Marylène",middleName:null,surname:"Combacau",fullName:"Marylène Combacau",slug:"marylene-combacau"},{id:"60750",title:"Dr.",name:"Didier",middleName:null,surname:"Mathon",fullName:"Didier Mathon",slug:"didier-mathon"}]},{id:"23628",type:"chapter",title:"Polysaccharides as Excipients for Ocular Topical Formulations",slug:"polysaccharides-as-excipients-for-ocular-topical-formulations",totalDownloads:4999,totalCrossrefCites:3,signatures:"Ylenia Zambito and Giacomo Di Colo",reviewType:"peer-reviewed",authors:[{id:"57344",title:"Dr.",name:"Ylenia",middleName:null,surname:"Zambito",fullName:"Ylenia Zambito",slug:"ylenia-zambito"},{id:"61639",title:"Prof.",name:"Giacomo",middleName:null,surname:"Di Colo",fullName:"Giacomo Di Colo",slug:"giacomo-di-colo"}]},{id:"23629",type:"chapter",title:"Nacre, a Natural Biomaterial",slug:"nacre-a-natural-biomaterial",totalDownloads:4720,totalCrossrefCites:1,signatures:"Marthe Rousseau",reviewType:"peer-reviewed",authors:[{id:"50051",title:"Dr.",name:"Marthe",middleName:null,surname:"Rousseau",fullName:"Marthe Rousseau",slug:"marthe-rousseau"}]},{id:"23630",type:"chapter",title:"Alumina and Zirconia Ceramic for Orthopaedic and Dental Devices",slug:"alumina-and-zirconia-ceramic-for-orthopaedic-and-dental-devices",totalDownloads:4848,totalCrossrefCites:9,signatures:"Giulio Maccauro, Pierfrancesco Rossi Iommetti, Luca Raffaelli and Paolo Francesco Manicone",reviewType:"peer-reviewed",authors:[{id:"38492",title:"Dr.",name:"Giulio",middleName:null,surname:"Maccauro",fullName:"Giulio Maccauro",slug:"giulio-maccauro"},{id:"54410",title:"Dr.",name:"Luca",middleName:null,surname:"Raffaelli",fullName:"Luca Raffaelli",slug:"luca-raffaelli"},{id:"61257",title:"Dr.",name:"Pierfrancesco",middleName:null,surname:"Rossi Iommeytti",fullName:"Pierfrancesco Rossi Iommeytti",slug:"pierfrancesco-rossi-iommeytti"},{id:"61258",title:"Dr.",name:"Paolo Francesco",middleName:null,surname:"Manicone",fullName:"Paolo Francesco Manicone",slug:"paolo-francesco-manicone"},{id:"61259",title:"Dr.",name:"Maria Silvia",middleName:null,surname:"Spinelli",fullName:"Maria Silvia Spinelli",slug:"maria-silvia-spinelli"},{id:"61260",title:"Dr.",name:"Calogero",middleName:null,surname:"Graci",fullName:"Calogero Graci",slug:"calogero-graci"}]},{id:"23631",type:"chapter",title:"Natural-Based Polyurethane Biomaterials for Medical Applications",slug:"natural-based-polyurethane-biomaterials-for-medical-applications",totalDownloads:4299,totalCrossrefCites:2,signatures:"Doina Macocinschi, Daniela Filip and Stelian Vlad",reviewType:"peer-reviewed",authors:[{id:"56189",title:"Dr.",name:"Doina",middleName:null,surname:"Macocinschi",fullName:"Doina Macocinschi",slug:"doina-macocinschi"},{id:"59259",title:"Dr.",name:"Daniela",middleName:null,surname:"Filip",fullName:"Daniela Filip",slug:"daniela-filip"},{id:"59260",title:"Dr.",name:"Stelian",middleName:null,surname:"Vlad",fullName:"Stelian Vlad",slug:"stelian-vlad"}]},{id:"23632",type:"chapter",title:"Collagen-Based Drug Delivery Systems for Tissue Engineering",slug:"collagen-based-drug-delivery-systems-for-tissue-engineering",totalDownloads:3960,totalCrossrefCites:6,signatures:"Mădălina Georgiana Albu, Irina Titorencu and Mihaela Violeta Ghica",reviewType:"peer-reviewed",authors:[{id:"50060",title:"Dr.",name:"Madalina Georgiana",middleName:null,surname:"Albu",fullName:"Madalina Georgiana Albu",slug:"madalina-georgiana-albu"},{id:"56578",title:"Dr.",name:"Irina",middleName:null,surname:"Titorencu",fullName:"Irina Titorencu",slug:"irina-titorencu"},{id:"56579",title:"Prof.",name:"Mihaela Violeta",middleName:null,surname:"Ghica",fullName:"Mihaela Violeta Ghica",slug:"mihaela-violeta-ghica"}]},{id:"23633",type:"chapter",title:"The Use of Biomaterials to Treat Abdominal Hernias",slug:"the-use-of-biomaterials-to-treat-abdominal-hernias",totalDownloads:8456,totalCrossrefCites:6,signatures:"Luciano Zogbi",reviewType:"peer-reviewed",authors:[{id:"56634",title:"Dr.",name:"Luciano",middleName:null,surname:"Zogbi",fullName:"Luciano Zogbi",slug:"luciano-zogbi"}]},{id:"23634",type:"chapter",title:"Biopolymers as Wound Healing Materials: Challenges and New Strategies",slug:"biopolymers-as-wound-healing-materials-challenges-and-new-strategies",totalDownloads:12887,totalCrossrefCites:11,signatures:"Ali Demir Sezer and Erdal Cevher",reviewType:"peer-reviewed",authors:[{id:"62389",title:"PhD.",name:"Ali Demir",middleName:null,surname:"Sezer",fullName:"Ali Demir Sezer",slug:"ali-demir-sezer"},{id:"129634",title:"Prof.",name:"Erdal",middleName:null,surname:"Cevher",fullName:"Erdal Cevher",slug:"erdal-cevher"}]},{id:"23635",type:"chapter",title:"Cellular Systems and Biomaterials for Nerve Regeneration in Neurotmesis Injuries",slug:"cellular-systems-and-biomaterials-for-nerve-regeneration-in-neurotmesis-injuries",totalDownloads:2859,totalCrossrefCites:3,signatures:"Ana Colette Maurício, Andrea Gärtner, Paulo Armada-da-Silva, Sandra Amado, Tiago Pereira, António Prieto Veloso, Artur Varejão, Ana Lúcia Luís and Stefano Geuna",reviewType:"peer-reviewed",authors:[{id:"48118",title:"Prof.",name:"Stefano",middleName:null,surname:"Geuna",fullName:"Stefano Geuna",slug:"stefano-geuna"},{id:"56285",title:"Prof.",name:"Ana Colette",middleName:null,surname:"Maurício",fullName:"Ana Colette Maurício",slug:"ana-colette-mauricio"},{id:"56287",title:"Prof.",name:"Paulo",middleName:null,surname:"Armada-Da-Silva",fullName:"Paulo Armada-Da-Silva",slug:"paulo-armada-da-silva"},{id:"56288",title:"Dr.",name:"António Prieto",middleName:null,surname:"Veloso",fullName:"António Prieto Veloso",slug:"antonio-prieto-veloso"},{id:"56289",title:"MSc.",name:"Andrea",middleName:null,surname:"Gartner",fullName:"Andrea Gartner",slug:"andrea-gartner"},{id:"56290",title:"MSc.",name:"Sandra",middleName:null,surname:"Amado",fullName:"Sandra Amado",slug:"sandra-amado"},{id:"56291",title:"Dr.",name:"Artur",middleName:null,surname:"Varejão",fullName:"Artur Varejão",slug:"artur-varejao"},{id:"56292",title:"Dr.",name:"Ana Lúcia",middleName:null,surname:"Luís",fullName:"Ana Lúcia Luís",slug:"ana-lucia-luis"},{id:"99505",title:"Dr.",name:"Tiago",middleName:null,surname:"Pereira",fullName:"Tiago Pereira",slug:"tiago-pereira"}]},{id:"23636",type:"chapter",title:"Extracellular Matrix Adjuvant for Vaccines",slug:"extracellular-matrix-adjuvant-for-vaccines",totalDownloads:2247,totalCrossrefCites:0,signatures:"Mark A. Suckow, Rae Ritchie and Amy Overby",reviewType:"peer-reviewed",authors:[{id:"56475",title:"Dr.",name:"Mark",middleName:null,surname:"Suckow",fullName:"Mark Suckow",slug:"mark-suckow"},{id:"56502",title:"Dr.",name:"Rae",middleName:null,surname:"Ritchie",fullName:"Rae Ritchie",slug:"rae-ritchie"},{id:"56503",title:"Ms",name:"Amy",middleName:null,surname:"Overby",fullName:"Amy Overby",slug:"amy-overby"}]}]},relatedBooks:[{type:"book",id:"395",title:"Biomaterials",subtitle:"Physics and Chemistry",isOpenForSubmission:!1,hash:"41507bb56706aec99bb59a645585d54e",slug:"biomaterials-physics-and-chemistry",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/395.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"22914",title:"Galectins: Structures, Binding Properties and Function in Cell Adhesion",slug:"galectins-structures-binding-properties-and-function-in-cell-adhesion",signatures:"Christiane E. Römer and Lothar Elling",authors:[{id:"58706",title:"Prof.",name:"Lothar",middleName:null,surname:"Elling",fullName:"Lothar Elling",slug:"lothar-elling"},{id:"61746",title:"MSc.",name:"Christiane Elisabeth",middleName:null,surname:"Römer",fullName:"Christiane Elisabeth Römer",slug:"christiane-elisabeth-romer"}]},{id:"22915",title:"Biomaterials and Epithesis, Our Experience in Maxillo Facial Surgery",slug:"biomaterials-and-epithesis-our-experience-in-maxillo-facial-surgery",signatures:"G. Fini, L.M. Moricca, A. Leonardi, S. Buonaccorsi and V. Pellacchia",authors:[{id:"61689",title:"Dr.",name:"Luca Maria",middleName:null,surname:"Moricca",fullName:"Luca Maria Moricca",slug:"luca-maria-moricca"},{id:"61702",title:"Prof.",name:"Giuseppina",middleName:null,surname:"Fini",fullName:"Giuseppina Fini",slug:"giuseppina-fini"},{id:"61703",title:"Dr.",name:"Alessandra",middleName:null,surname:"Leonardi",fullName:"Alessandra Leonardi",slug:"alessandra-leonardi"},{id:"61704",title:"Dr.",name:"Sara",middleName:null,surname:"Buonaccorsi",fullName:"Sara Buonaccorsi",slug:"sara-buonaccorsi"},{id:"61705",title:"Dr.",name:"Valentina",middleName:null,surname:"Pellacchia",fullName:"Valentina Pellacchia",slug:"valentina-pellacchia"},{id:"61706",title:"Dr.",name:"Luciano",middleName:null,surname:"D",fullName:"Luciano D",slug:"luciano-d"},{id:"61707",title:"Dr.",name:"Elidon",middleName:null,surname:"Mici",fullName:"Elidon Mici",slug:"elidon-mici"},{id:"115981",title:"Dr.",name:"Laura",middleName:null,surname:"Frontero",fullName:"Laura Frontero",slug:"laura-frontero"}]},{id:"22916",title:"Nanostructural Chemically Bonded Ca-Aluminate Based Bioceramics",slug:"nanostructural-chemically-bonded-ca-aluminate-based-bioceramics",signatures:"Leif Hermansson",authors:[{id:"57192",title:"Prof.",name:"Leif",middleName:null,surname:"Hermansson",fullName:"Leif Hermansson",slug:"leif-hermansson"}]},{id:"22917",title:"Ulvan: A Versatile Platform of Biomaterials from Renewable Resources",slug:"ulvan-a-versatile-platform-of-biomaterials-from-renewable-resources",signatures:"Federica Chiellini and Andrea Morelli",authors:[{id:"60263",title:"Dr.",name:"Federica",middleName:null,surname:"Chiellini",fullName:"Federica Chiellini",slug:"federica-chiellini"},{id:"60747",title:"Dr.",name:"Andrea",middleName:null,surname:"Morelli",fullName:"Andrea Morelli",slug:"andrea-morelli"}]},{id:"22918",title:"Silanization with APTES for Controlling the Interactions Between Stainless Steel and Biocomponents: Reality vs Expectation",slug:"silanization-with-aptes-for-controlling-the-interactions-between-stainless-steel-and-biocomponents-r",signatures:"Jessem Landoulsi, Michel J. Genet, Karim El Kirat, Caroline Richard, Sylviane Pulvin and Paul G. Rouxhet",authors:[{id:"57300",title:"Prof.",name:"Paul",middleName:null,surname:"Rouxhet",fullName:"Paul Rouxhet",slug:"paul-rouxhet"},{id:"61024",title:"Dr.",name:"Jessem",middleName:null,surname:"Landoulsi",fullName:"Jessem Landoulsi",slug:"jessem-landoulsi"},{id:"61025",title:"Dr.",name:"Michel J.",middleName:null,surname:"Genet",fullName:"Michel J. Genet",slug:"michel-j.-genet"},{id:"61026",title:"Dr.",name:"Karim",middleName:null,surname:"El Kirat",fullName:"Karim El Kirat",slug:"karim-el-kirat"},{id:"61027",title:"Prof.",name:"Caroline",middleName:null,surname:"Richard",fullName:"Caroline Richard",slug:"caroline-richard"},{id:"61028",title:"Prof.",name:"Sylviane",middleName:null,surname:"Pulvin",fullName:"Sylviane Pulvin",slug:"sylviane-pulvin"}]},{id:"22919",title:"Human Dentin as Novel Biomaterial for Bone Regeneration",slug:"human-dentin-as-novel-biomaterial-for-bone-regeneration",signatures:"Masaru Murata, Toshiyuki Akazawa, Masaharu Mitsugi, In-Woong Um, Kyung-Wook Kim and Young-Kyun Kim",authors:[{id:"61607",title:"Dr.",name:"Masaru",middleName:null,surname:"Murata",fullName:"Masaru Murata",slug:"masaru-murata"},{id:"62246",title:"Dr.",name:"Toshiyuki",middleName:null,surname:"Akazawa",fullName:"Toshiyuki Akazawa",slug:"toshiyuki-akazawa"},{id:"62247",title:"Prof.",name:"Masaharu",middleName:null,surname:"Mitsugi",fullName:"Masaharu Mitsugi",slug:"masaharu-mitsugi"},{id:"62248",title:"Prof.",name:"In-Woong",middleName:null,surname:"Um",fullName:"In-Woong Um",slug:"in-woong-um"},{id:"62249",title:"Prof.",name:"Kyung-Wook",middleName:null,surname:"Kim",fullName:"Kyung-Wook Kim",slug:"kyung-wook-kim"},{id:"62484",title:"Prof.",name:"Young-Kyun",middleName:null,surname:"Kim",fullName:"Young-Kyun Kim",slug:"young-kyun-kim"}]},{id:"22920",title:"Comparative Metal Ion Binding to Native and Chemically Modified Datura innoxia Immobilized Biomaterials",slug:"comparative-metal-ion-binding-to-native-and-chemically-modified-datura-innoxia-immobilized-biomateri",signatures:"Gary D. Rayson and Patrick A. Williams",authors:[{id:"60445",title:"Prof.",name:"Gary",middleName:null,surname:"Rayson",fullName:"Gary Rayson",slug:"gary-rayson"},{id:"60913",title:"Mr.",name:"Patrick",middleName:null,surname:"Williams",fullName:"Patrick Williams",slug:"patrick-williams"}]},{id:"22921",title:"Decellularization, Stabilization and Functionalization of Collagenous Tissues Used as Cardiovascular Biomaterials",slug:"decellularization-stabilization-and-functionalization-of-collagenous-tissues-used-as-cardiovascular-",signatures:"Birzabith Mendoza-Novelo and Juan Valerio Cauich-Rodríguez",authors:[{id:"62414",title:"Dr.",name:"Juan",middleName:"Valerio",surname:"Cauich-Rodríguez",fullName:"Juan Cauich-Rodríguez",slug:"juan-cauich-rodriguez"},{id:"62486",title:"PhD.",name:"Birzabith",middleName:null,surname:"Mendoza-Novelo",fullName:"Birzabith Mendoza-Novelo",slug:"birzabith-mendoza-novelo"}]},{id:"22922",title:"Research on Mg-Zn-Ca Alloy as Degradable Biomaterial",slug:"research-on-mg-zn-ca-alloy-as-degradable-biomaterial",signatures:"B.P. Zhang, Y. Wang and L. Geng",authors:[{id:"54477",title:"Dr",name:"Baoping",middleName:null,surname:"Zhang",fullName:"Baoping Zhang",slug:"baoping-zhang"},{id:"140304",title:"Dr.",name:"You",middleName:null,surname:"Wang",fullName:"You Wang",slug:"you-wang"},{id:"140305",title:"Dr.",name:"Lin",middleName:null,surname:"Geng",fullName:"Lin Geng",slug:"lin-geng"}]},{id:"22923",title:"Biomechanical Properties of Synovial Fluid in/Between Peripheral Zones of Articular Cartilage",slug:"biomechanical-properties-of-synovial-fluid-in-between-peripheral-zones-of-articular-cartilage",signatures:"Miroslav Petrtyl, Jaroslav Lisal and Jana Danesova",authors:[{id:"60810",title:"Prof.",name:"Miroslav",middleName:null,surname:"Petrtyl",fullName:"Miroslav Petrtyl",slug:"miroslav-petrtyl"},{id:"60819",title:"Dr.",name:"Jaroslav",middleName:null,surname:"Lisal",fullName:"Jaroslav Lisal",slug:"jaroslav-lisal"},{id:"60820",title:"Dr.",name:"Jana",middleName:null,surname:"Danesova",fullName:"Jana Danesova",slug:"jana-danesova"}]},{id:"22924",title:"Charge Transport and Electrical Switching in Composite Biopolymers",slug:"charge-transport-and-electrical-switching-in-composite-biopolymers",signatures:"Gabriel Katana and Wycliffe Kipnusu",authors:[{id:"59195",title:"Prof.",name:"Gabriel",middleName:null,surname:"Katana",fullName:"Gabriel Katana",slug:"gabriel-katana"},{id:"61572",title:"Mr.",name:"Wycliffe",middleName:null,surname:"Kipnusu",fullName:"Wycliffe Kipnusu",slug:"wycliffe-kipnusu"}]},{id:"22925",title:"Biomimetic Materials as Potential Medical Adhesives – Composition and Adhesive Properties of the Material Coating the Cuvierian Tubules Expelled by Holothuria dofleinii",slug:"biomimetic-materials-as-potential-medical-adhesives-composition-and-adhesive-properties-of-the-mater",signatures:"Yong Y. Peng, Veronica Glattauer, Timothy D. Skewes, Jacinta F. White, Kate M. Nairn, Andrew N. McDevitt, Christopher M. Elvin, Jerome A. Werkmeister, Lloyd D. Graham and John A.M. Ramshaw",authors:[{id:"55499",title:"Mr.",name:"John",middleName:null,surname:"Ramshaw",fullName:"John Ramshaw",slug:"john-ramshaw"}]},{id:"22926",title:"Mechanical and Biological Properties of Bio-Inspired Nano-Fibrous Elastic Materials from Collagen",slug:"mechanical-and-biological-properties-of-bio-inspired-nano-fibrous-elastic-materials-from-collagen",signatures:"Nobuhiro Nagai, Ryosuke Kubota, Ryohei Okahashi and Masanobu Munekata",authors:[{id:"51544",title:"Dr.",name:"Nobuhiro",middleName:null,surname:"Nagai",fullName:"Nobuhiro Nagai",slug:"nobuhiro-nagai"},{id:"61541",title:"Mr.",name:"Ryosuke",middleName:null,surname:"Kubota",fullName:"Ryosuke Kubota",slug:"ryosuke-kubota"},{id:"61542",title:"Mr.",name:"Ryohei",middleName:null,surname:"Okahashi",fullName:"Ryohei Okahashi",slug:"ryohei-okahashi"},{id:"61543",title:"Prof.",name:"Masanobu",middleName:null,surname:"Munekata",fullName:"Masanobu Munekata",slug:"masanobu-munekata"}]},{id:"22927",title:"In Silico Study of Hydroxyapatite and Bioglass®: How Computational Science Sheds Light on Biomaterials",slug:"in-silico-study-of-hydroxyapatite-and-bioglass-how-computational-science-sheds-light-on-biomaterials",signatures:"Marta Corno, Fabio Chiatti, Alfonso Pedone and Piero Ugliengo",authors:[{id:"60583",title:"Prof.",name:"Piero",middleName:null,surname:"Ugliengo",fullName:"Piero Ugliengo",slug:"piero-ugliengo"},{id:"60584",title:"Dr.",name:"Marta",middleName:null,surname:"Corno",fullName:"Marta Corno",slug:"marta-corno"},{id:"61350",title:"MSc.",name:"Fabio",middleName:null,surname:"Chiatti",fullName:"Fabio Chiatti",slug:"fabio-chiatti"},{id:"61638",title:"Dr.",name:"Alfonso",middleName:null,surname:"Pedone",fullName:"Alfonso Pedone",slug:"alfonso-pedone"}]},{id:"22928",title:"The Use of Vibration Principles to Characterize the Mechanical Properties of Biomaterials",slug:"the-use-of-vibration-principles-to-characterize-the-mechanical-properties-of-biomaterials",signatures:"Osvaldo H. Campanella, Hartono Sumali, Behic Mert and Bhavesh Patel",authors:[{id:"49546",title:"Prof.",name:"Osvaldo",middleName:null,surname:"Campanella",fullName:"Osvaldo Campanella",slug:"osvaldo-campanella"},{id:"59818",title:"Prof.",name:"Behic",middleName:null,surname:"Mert",fullName:"Behic Mert",slug:"behic-mert"},{id:"59819",title:"Dr.",name:"Patel",middleName:"K",surname:"Bhavesh",fullName:"Patel Bhavesh",slug:"patel-bhavesh"},{id:"59820",title:"Dr.",name:"Hartono",middleName:null,surname:"Sumali",fullName:"Hartono Sumali",slug:"hartono-sumali"}]},{id:"22929",title:"The Effects of Endurance Running Training on Young Adult Bone: Densitometry vs. Biomaterial Properties",slug:"the-effects-of-endurance-running-training-on-young-adult-bone-densitometry-vs-biomaterial-properties",signatures:"Tsang-Hai Huang, Ming-Yao Chang, Kung-Tung Chen, Sandy S. Hsieh and Rong-Sen Yang",authors:[{id:"50557",title:"Prof.",name:"Rong-Sen",middleName:null,surname:"Yang",fullName:"Rong-Sen Yang",slug:"rong-sen-yang"},{id:"59842",title:"Dr.",name:"Tsang-Hai",middleName:null,surname:"Huang",fullName:"Tsang-Hai Huang",slug:"tsang-hai-huang"},{id:"59843",title:"Mr.",name:"Ming-Yao",middleName:null,surname:"Chang",fullName:"Ming-Yao Chang",slug:"ming-yao-chang"},{id:"109705",title:"Dr.",name:"Kung-Tung",middleName:null,surname:"Chen",fullName:"Kung-Tung Chen",slug:"kung-tung-chen"},{id:"109709",title:"Prof.",name:"Sandy",middleName:null,surname:"Hsieh",fullName:"Sandy Hsieh",slug:"sandy-hsieh"}]},{id:"22930",title:"Effect of the Er, Cr: YSGG Laser Parameters on Shear Bond Strength and Microstructure on Human Dentin Surface",slug:"effect-of-the-er-cr-ysgg-laser-parameters-on-shear-bond-strength-and-microstructure-on-human-dentin-",signatures:"Eun Mi Rhim, Sungyoon Huh, Duck Su Kim, Sun-Young Kim, Su-Jin Ahn, Kyung Lhi Kang and Sang Hyuk Park",authors:[{id:"60471",title:"Prof.",name:"Sang Hyuk",middleName:null,surname:"Park",fullName:"Sang Hyuk Park",slug:"sang-hyuk-park"},{id:"61611",title:"Prof.",name:"Eun Mi",middleName:null,surname:"Rhim",fullName:"Eun Mi Rhim",slug:"eun-mi-rhim"},{id:"98423",title:"Dr.",name:"Duck Su",middleName:null,surname:"Kim",fullName:"Duck Su Kim",slug:"duck-su-kim"},{id:"98428",title:"Prof.",name:"Sun-Young",middleName:null,surname:"Kim",fullName:"Sun-Young Kim",slug:"sun-young-kim"},{id:"98429",title:"Dr.",name:"Su-Jin",middleName:null,surname:"Ahn",fullName:"Su-Jin Ahn",slug:"su-jin-ahn"},{id:"98431",title:"Prof.",name:"Kyung Lhi",middleName:null,surname:"Kang",fullName:"Kyung Lhi Kang",slug:"kyung-lhi-kang"},{id:"100775",title:"Dr.",name:"Sungyoon",middleName:null,surname:"Huh",fullName:"Sungyoon Huh",slug:"sungyoon-huh"}]},{id:"22931",title:"Elaboration and Characterization of Calcium Phosphate Biomaterial for Biomedical Applications",slug:"elaboration-and-characterization-of-calcium-phosphate-biomaterial-for-biomedical-applications",signatures:"Foued Ben Ayed",authors:[{id:"50775",title:"Dr.",name:"Ben Ayed",middleName:null,surname:"Foued",fullName:"Ben Ayed Foued",slug:"ben-ayed-foued"}]},{id:"22932",title:"Fracture Mechanisms of Biodegradable PLA and PLA/PCL Blends",slug:"fracture-mechanisms-of-biodegradable-pla-and-pla-pcl-blends",signatures:"Mitsugu Todo and Tetsuo Takayama",authors:[{id:"56090",title:"Prof.",name:"Mitsugu",middleName:null,surname:"Todo",fullName:"Mitsugu Todo",slug:"mitsugu-todo"},{id:"61234",title:"Dr.",name:"Tetsuo",middleName:null,surname:"Takayama",fullName:"Tetsuo Takayama",slug:"tetsuo-takayama"}]},{id:"22933",title:"Cell Adhesion and Spreading on an Intrinsically Anti-Adhesive PEG Biomaterial",slug:"cell-adhesion-and-spreading-on-an-intrinsically-anti-adhesive-peg-biomaterial",signatures:"Marga C. Lensen, Vera A. Schulte and Mar Diez",authors:[{id:"56428",title:"Prof.",name:"Marga",middleName:null,surname:"Lensen",fullName:"Marga Lensen",slug:"marga-lensen"},{id:"98116",title:"Ms.",name:"Vera",middleName:null,surname:"Schulte",fullName:"Vera Schulte",slug:"vera-schulte"},{id:"98118",title:"Ms.",name:"Mar",middleName:null,surname:"Diez",fullName:"Mar Diez",slug:"mar-diez"}]},{id:"22934",title:"A Preliminary In Vivo Study on the Histocompatibility of Silk Fibroin",slug:"a-preliminary-in-vivo-study-on-the-histocompatibility-of-silk-fibroin",signatures:"Lu Yan, Zhao Xia, Shao Zhengzhong, Cao Zhengbing and Cai Lihui",authors:[{id:"61256",title:"Dr.",name:"Yan",middleName:null,surname:"Lu",fullName:"Yan Lu",slug:"yan-lu"},{id:"61734",title:"Dr.",name:"Zhao",middleName:null,surname:"Xia",fullName:"Zhao Xia",slug:"zhao-xia"},{id:"61741",title:"Dr.",name:"Jiao",middleName:null,surname:"Wei",fullName:"Jiao Wei",slug:"jiao-wei"}]},{id:"22935",title:"Histopatological Effect Characteristics of Various Biomaterials and Monomers Used in Polymeric Biomaterial Production",slug:"histopatological-effect-characteristics-of-various-biomaterials-and-monomers-used-in-polymeric-bioma",signatures:"Serpil Ünver Saraydin and Dursun Saraydin",authors:[{id:"54924",title:"Prof.",name:"Serpil",middleName:null,surname:"Ünver Saraydın",fullName:"Serpil Ünver Saraydın",slug:"serpil-unver-saraydin"},{id:"58334",title:"Prof.",name:"Dursun",middleName:null,surname:"Saraydin",fullName:"Dursun Saraydin",slug:"dursun-saraydin"}]},{id:"22936",title:"Facial Remodelling and Biomaterial",slug:"facial-remodelling-and-biomaterial",signatures:"G. Fini, L.M. Moricca, A. Leonardi, S. Buonaccorsi and V. Pellacchia",authors:[{id:"61689",title:"Dr.",name:"Luca Maria",middleName:null,surname:"Moricca",fullName:"Luca Maria Moricca",slug:"luca-maria-moricca"}]},{id:"22937",title:"Biomaterials in Urology - Beyond Drug Eluting and Degradable - A Rational Approach to Ureteral Stent Design",slug:"biomaterials-in-urology-beyond-drug-eluting-and-degradable-a-rational-approach-to-ureteral-stent-des",signatures:"Dirk Lange, Chelsea N. Elwood and Ben H. Chew",authors:[{id:"56152",title:"Dr.",name:"Ben",middleName:null,surname:"Chew",fullName:"Ben Chew",slug:"ben-chew"},{id:"61462",title:"Dr.",name:"Dirk",middleName:null,surname:"Lange",fullName:"Dirk Lange",slug:"dirk-lange"},{id:"61463",title:"Dr.",name:"Chelsea",middleName:null,surname:"Elwood",fullName:"Chelsea Elwood",slug:"chelsea-elwood"}]},{id:"22938",title:"Candida Biofilms on Oral Biomaterials",slug:"candida-biofilms-on-oral-biomaterials",signatures:"Philippe Courtois",authors:[{id:"56756",title:"Dr.",name:"Philippe",middleName:null,surname:"Courtois",fullName:"Philippe Courtois",slug:"philippe-courtois"}]}]}],publishedBooks:[{type:"book",id:"395",title:"Biomaterials",subtitle:"Physics and Chemistry",isOpenForSubmission:!1,hash:"41507bb56706aec99bb59a645585d54e",slug:"biomaterials-physics-and-chemistry",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/395.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1486",title:"Biomaterials Science and Engineering",subtitle:null,isOpenForSubmission:!1,hash:"38aeff8880e6259e624707abda269b0f",slug:"biomaterials-science-and-engineering",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/1486.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1487",title:"Biomaterials",subtitle:"Applications for Nanomedicine",isOpenForSubmission:!1,hash:"696e143e9bcc2385c45795c2d73cdafc",slug:"biomaterials-applications-for-nanomedicine",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/1487.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7727",title:"Biotechnology and Bioengineering",subtitle:null,isOpenForSubmission:!1,hash:"1e6603fadccf154db3bc2b7a1e473121",slug:"biotechnology-and-bioengineering",bookSignature:"Eduardo Jacob -Lopes and Leila Queiroz Zepka",coverURL:"https://cdn.intechopen.com/books/images_new/7727.jpg",editedByType:"Edited by",editors:[{id:"171980",title:"Dr.",name:"Eduardo",surname:"Jacob-Lopes",slug:"eduardo-jacob-lopes",fullName:"Eduardo Jacob-Lopes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6280",title:"Biomaterials",subtitle:"Physics and Chemistry - New Edition",isOpenForSubmission:!1,hash:"4d45002a20a9496ff80f5c0166d9be33",slug:"biomaterials-physics-and-chemistry-new-edition",bookSignature:"Rosario Pignatello and Teresa Musumeci",coverURL:"https://cdn.intechopen.com/books/images_new/6280.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],publishedBooksByAuthor:[{type:"book",id:"508",title:"Biomedical Engineering",subtitle:"Frontiers and Challenges",isOpenForSubmission:!1,hash:"7f5bfc734fd607df80a0dc2fe965b313",slug:"biomedical-engineering-frontiers-and-challenges",bookSignature:"Reza Fazel-Rezai",coverURL:"https://cdn.intechopen.com/books/images_new/508.jpg",editedByType:"Edited by",editors:[{id:"1995",title:"Dr.",name:"Reza",surname:"Fazel-Rezai",slug:"reza-fazel-rezai",fullName:"Reza Fazel-Rezai"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1487",title:"Biomaterials",subtitle:"Applications for Nanomedicine",isOpenForSubmission:!1,hash:"696e143e9bcc2385c45795c2d73cdafc",slug:"biomaterials-applications-for-nanomedicine",bookSignature:"Rosario Pignatello",coverURL:"https://cdn.intechopen.com/books/images_new/1487.jpg",editedByType:"Edited by",editors:[{id:"64447",title:"Prof.",name:"Rosario",surname:"Pignatello",slug:"rosario-pignatello",fullName:"Rosario Pignatello"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},onlineFirst:{chapter:{type:"chapter",id:"62673",title:"ASIC Commercialization Analysis: Technology Portfolios and the Innovative Performance of ASIC Firms during Technology Evolution",doi:"10.5772/intechopen.79647",slug:"asic-commercialization-analysis-technology-portfolios-and-the-innovative-performance-of-asic-firms-d",body:'\n
We examine the relationship between the size and diversity of ASIC firms’ technology portfolios and their innovative performance as ASIC technology evolves.
\nFor many technology-based firms, in-house developed technology is crucial for the creation of innovations and for capturing innovation returns [1, 2, 3]. In-house technology development enables firms to increase the complexity of their innovations, so it becomes difficult for competitors to imitate them [4]. It also enables firms to maintain secrecy and, in that way, to establish a lead time [5]. Especially, technology that is classified as “distinctive competencies” [6] and that forms the core of the firm’s technological capabilities will mostly be developed in-house because of these reasons. In-house technology development also creates absorptive capacity, i.e., the knowledge that enables firms to better understand, source, and use external technology [5, 7, 8].
\nIn this chapter, we focus on the effects of the size and diversity of the in-house ASIC technology portfolio on ASIC firms’ innovative performance. The size of the portfolio reflects the firms’ total efforts to develop ASIC technology in-house. The diversity of the portfolio reflects how firms’ development efforts are spread over various ASIC sub-technologies.
\nThe relationship between the size and diversity of firms’ internal technology portfolios and their innovative performance is complex, and the results of the previous research have been conflicting. We contribute to this research by investigating the moderating effect of technology evolution. As a moderator, we use Abernathy and Utterback’s concept of technology evolution of an industry [9]. They distinguish three evolutionary phases: the fluid phase, the transitional phase, and the specific phase. Currently, ASIC technology is in the specific phase, according to patent counts, and this is also indicated by the industry’s technology trends. The exact evolutionary phase may differ per ASIC sub-technology: gate array technology is at the end of its evolution, standard cell technology is in the late specific phase, and PLD technology is also in the specific phase. A competing technology such as FPGA is earlier in the specific phase. Emerging technologies, whether they are labeled as ASIC or as competing with ASIC, are in the fluid phase.
\nIn the early, fluid phase of technology evolution, technological uncertainty is high, and firms need to keep various development options open to cope with that uncertainty. They need to develop large and diverse technology portfolios that are useful for various technology development scenarios. In the later, specific phase of technology evolution, after a “dominant design” has been established [10], technological uncertainty is much lower. This means that there is less need for large and diverse technology portfolios. This enables firms to focus on those technologies they can best exploit.
\nManagers of technology-based firms need to know whether and when during the evolution of a technology, investments in large or diverse technology portfolios contribute to their firms’ innovative performance. Building and maintaining such technology portfolios require large and risky resource investments, and it is therefore important to ensure the returns to these investments.
\nTo study the effects of portfolio size and diversity on innovative performance during technology evolution, we developed a longitudinal dataset of 67 firms from the ASIC industry over the period 1986–2003. Our results support the moderating effect of technology evolution on the relationship between technology portfolio size and diversity and firms’ innovative performance. Our findings contribute to a better understanding of the complexity of these relationships.
\nThe practical implication is that ASIC firms need to adjust their technology sourcing strategy according to the phase of ASIC technology evolution. In earlier stages of technology evolution, investing in a relatively large and diverse technology portfolio seems to be a better approach to improve innovative performance. In later stages, focusing on a relatively smaller and specialized technology portfolio seems to improve innovative performance. ASIC firms that focus on multiple technology areas need to balance their technology portfolios across the areas: focusing for the late-evolution technologies and investing and diversifying for early-evolution technologies.
\nThe ASIC industry is a part of the semiconductor industry that can be characterized as an independent market for design modules [11] that has been a driving force behind major technological breakthroughs in the semiconductor industry [12]. The history of this industry is well known: the inventions of the point contact transistor (by John Bardeen and Walter Brattain in 1947) and the junction transistor (by William Shockley in 1948) in the Bell Labs provided, together with the diffusion-oxide masking photo process (1954), the integrated circuit (1958), and planar technology (1959), and the foundations for the development of the global semiconductor industry [11, 13]. By 1961, it had developed into a worldwide billion-dollar industry [13]. Although the development of ASIC technology began at the end of the 1960s [14], it became popular in the 1980s [15]. In the 1980s it became possible to combine standard integrated circuits (ICs) into custom ICs that were tailored to particular systems or applications or Application-Specific Integrated Circuits (ASICs) [16].
\nThe successful development of ASICs requires the knowledge and competencies of different types of firms [17]. As a result, it is an industry characterized by newcomers, strategic alliances, and mergers and acquisitions [17]. The dynamic patterns and the need for different knowledge and competencies make it an attractive industry for our type of research. The major firms currently active in the ASIC industry are Texas Instruments, Infineon Technologies, STMicroelectronics, Renesas Electronics, Analog Devices (which acquired Linear Technology in 2017), Maxim Integrated Products, NXP Semiconductors, ON Semiconductor, Qualcomm, and Intel [18]. All these major players are active in multiple segments of the semiconductor industry, ASIC being one of them.
\nAnalogous to most semiconductor firms, ASIC firms initially worked according to the integrated device manufacturer (IDM) business model. They vertically integrated every aspect of chip production, from design to manufacturing, packaging, and testing [19]. In 1984, Xilinx was the first firm adopting a “fabless” business model, focusing on the design of ASICs, and outsourcing its manufacturing to other “IDM” firms [19]. Soon after, in 1987, TSMC adopted a pure foundry business model, focusing on the manufacturing [20]. During the 1980s, most firms still used the IDM model. By now, most semiconductor firms use the fabless model, although a few major ones, such as Intel and STMicroelectronics, still use the IDM model, still accounting for about 55% of the market [21].
\nThe industry reports generally define three ASIC subsegments:
Full-custom design: a circuit that is customized on all mask layers and is sold to one customer.
Semi-custom design: a circuit that has one or more customized mask layers, but does not have all mask layers customized and is sold to one customer. This segment includes gate array and standard cell technologies [22], although standard cell is sometimes placed separately in between full-custom and semi-custom designs.
Programmable logic devices (PLD): a circuit with fuse that may be programmed (customized) and, in some cases, reprogrammed by the user. This segment includes CPLD, SPLD, and PAL technologies. FPGA technologies have in the past been regarded as a special kind of PLD but are now generally considered as a technology that competes with ASIC (see, e.g., [23]).
The three categories contain different devices with the same system functionalities that can be programmed at different moments in the development process; by the vendor (for standard cell, gate array), by the designer, prior to assembly (for full custom); or by the user (for PLD). Programmable logic devices offer the cheapest solution for low volumes. If volumes are higher and exceed a few thousand units, gate arrays offer the best solution. Full-custom devices are the best choice when production volumes exceed hundreds of thousands.
\nFor the total ASIC industry, we can define the various phases of technology evolution based on our data. Based on the technological developments of all firms together, starting with the first patents developed in the ASIC industry, we can put the
Number of ASIC firms.
Looking at the ASIC subsegments, we start with gate array technology, which existed in some form since the mid-1960s but did not capture a sizable share until around 1983 [15]. By the 2010s this technology was hardly applied anymore [25]. In the mid-1980s, the standard cell was implemented. The first type of programmable logic device was invented in the 1970s [26], but the technology became more popular in the 1980s, and the PLD submarket became one of the fastest-growing sectors in the semiconductor industry. Figures 2 and 3 show the units sold and the prices per subsegment. These figures clearly indicate that the gate array technology evolution preceded the standard cell and PLD technologies in time.
\nASIC units sold (in millions).
Price per unit (in USD).
We identify four major technology trends in the ASIC industry (see also [27, 28]). The first trend is the continuation of Moore’s law through increasingly smaller DRAM pitch scales, increasing numbers of mask layers, and multi-patterning in lithography [29]. This trend is commonly referred to as “more Moore” [27, 28]. It entails strongly increasing cost of development of ASICs. As a consequence, minimum efficient design scale (numbers of ASICs sold per design) increases, and only few large design firms (fabless or IDM) are able to continue profitable operations, an indication of a mature technological field [9]. This development also fits the trend of firms concentrating on core competencies by adopting a fabless business model.
\nThe second trend is increased efficiency in manufacturing due to wafer-size increases. The share of 300 mm wafers is still increasing [30], and efforts were made to increase wafer sizes from 300 to 450 mm [29]), although the consortium of firms involved abandoned its efforts at the end of 2016 [31]. This trend is mainly production process innovation, which like “more Moore” requires large investments in manufacturing facilities [29]. This, too, is a logical development in a mature technological field, and it fits in the trend of firms focusing on core competencies by adopting a foundry business model. Here, too, relatively few firms will be able to profitably carry out such investments because the minimum efficient scale of manufacturing ASICs increases.
\nThese first two technology trends fit with market demand trends of ASICs as commodities for high-volume applications, such as Internet of Things, which require a lot of ASICs but not necessarily require leading-edge technology. Other markets with such demand are virtual and augmented reality, automotive electronics, smartphones, personal computing, and wearable electronics [32].
\nThe third trend is added functionality, resulting in increasingly complex products for advanced applications such as machine learning or blockchain mining. This trend is commonly referred to as “more than Moore” [27, 28]. Examples of products are “software-defined hardware” or combinations of ASICs and general-purpose chips on a single-circuit board, like “domain-specific system-on-chip” [33] or “system-in-package” designs [27, 28]. This trend, too, indicates a relatively mature technological field with a focus on specific, albeit high-end, applications. This trend is accompanied by a shift from technology push-based roadmapping, to a more interactive approach in which multiple stakeholders are involved in defining future developments [27].
\nAs a note on trends one till three: a mature technological field does not mean that technology does not develop or improve anymore. The technology still develops, e.g., in speed, power consumption, cost reductions, and performance for specific applications, but it develops in a relatively predictable direction and with a relatively predictable speed. This does not mean that such technology development becomes easier for firms: while the purely technological risks and uncertainties may be lower than before, the resource investments and the business risks are considerable, as are the business opportunities. In business terms, the industry moved from exploring new technologies to exploiting existing technologies.
\nThe fourth trend, perhaps more accurately a collection of trends, is the emergence of new technologies such as quantum computing or nano-carbon technology [28]. This trend deals with completely new technological fields, and it is not always immediately clear whether these are still related to “ASIC” or the emergence of a completely new industry. Such uncertainty is a characteristic of the fluid phase of technology evolution [9]. This could be referred to as “beyond Moore.”
\nTechnological knowledge is a resource that helps create innovation by enabling firms to add value to incoming factors of production [34]. Here, we look at the size and the diversity of firms’ technology portfolios. We would normally expect a positive effect of the
Technological knowledge embedded in patents is often converted into innovative products that contribute to firm performance (see, e.g., [35]). Given a certain efficiency of this function, more input (patents) will result in higher performance.
Knowledge as a resource is indivisible and self-generating, which cause it to have strong static and dynamic economies of scale in its application [3]. Indivisibility [36] means that a certain critical mass of technological knowledge is needed before it can be productively applied. Therefore, more technological knowledge can be expected to create higher innovative performance after this critical mass is reached. Self-generating ability [37] means that new relevant knowledge may emerge from the technology development process as additional output besides the normal output of (new) goods and services. The accumulated knowledge then becomes a basis for subsequent technological developments [7].
A larger technology portfolio allows for more recombination of knowledge (e.g., [38]). The possible number of combinations of knowledge exponentially grows with the size of the portfolio.
However, the relationship between technology portfolio size and innovative performance is more complex than expected. Lin et al. [39] find nonsignificant effects of technology portfolio (technology stock) on firm performance metrics. Artz et al. [40] show that, while the direct effects of R&D input to patent output (invention) and of patent input to product announcement output (innovation) are positive as expected, the indirect effect of R&D input on product announcement output is unexpectedly U-shaped and the indirect effect of patent input on firm performance is even negative.
\nThe choice between a diverse and a focused knowledge base is one of the fundamental choices in a firm’s knowledge strategies [1]. We would normally expect a positive effect of
A diverse technology portfolio may generate economies of scope, or “synergies,” meaning that it is more efficient to develop (related) technologies together than independently [3, 41].
Combining various technologies may generate “causal ambiguity,” meaning that competitors are unable to determine the source of a firm’s competitive advantage and therefore may have difficulty imitating it [4].
If we see innovation as a process of “recombinant search” for new combinations, a more diverse portfolio may result in many more possible combinations [38, 42].
However, this relationship, too, is more complex than expected. More diversity leads to increased coordination cost, which may partly or wholly offset the benefits, dependent on the strength of the firm’s “integrative capabilities” [3]. Distributed technological capabilities may limit the firm’s focus to develop strong core capabilities [43, 44]. The recombinant search advantage of a diverse portfolio depends on the degree of interdependency between components and on the size of the search space. Fleming and Sorenson [38] show that when interdependency is too high or too low, and when the search space is too large, recombinant search will become progressively less efficient. Building on this literature, Leten et al. [44] and Huang and Chen [45] argue that the relationship between diversity and innovative performance is complex and nonlinear. Lin [46] finds a nonsignificant relationship and suggests that diversity may interact with other variables.
\nA possible explanation for these complex results is that there is another variable that moderates the relationships between the size and diversity of a technology portfolio and innovative performance. We propose that technology evolution of an industry [9] is such a variable and that we may (partially) explain the complexities by including it in our model. We use Utterback’s model [24] for our definition of technology evolution. This is a refined and validated version of the original Abernathy and Utterback model [9]. It specifies three phases in technology evolution: the fluid phase, the transitional phase, and the specific phase.
\nDuring the
They need to keep many options open and need to explore multiple different technological trajectories. To gain innovative performance in the early phases of technology evolution, firms need a large and diverse technology portfolio. A diverse technological knowledge base allows a firm to adapt [2] to turbulent environments and to develop a higher number of technologies. It also reduces the danger of a lock-in into dead-end technologies [48], and it hedges against the risks of developing the wrong technology [49]. As a result, diversification is positively associated with innovative performance. As technological scientific knowledge solutions are not readily available internally or externally, they need to be developed, adding to the portfolio size. Often, because of indivisibilities, various sub-technologies have to be developed simultaneously to create feasible technology solutions. When firms plan to source knowledge externally, they first need to develop a stock of knowledge internally that will enable them to scan and absorb external knowledge [7, 50]. During technology development, an increase in the number of components results in an exponentially larger number of possible combinations [38]. Grant [2] argues that different types of specialized knowledge are complements rather than substitutes, meaning that they are most useful when combined, or that there are economies of scope. A diverse technological knowledge base is required to be creative [47] and to create cross-fertilization between technological areas, which increases innovative performance [48]. Incidentally, this kind of cross-fertilization resembles the layout of the Bell Labs Murray Hill building in which the transistor was invented by design enabling—almost forcing—close contacts between researchers from different technological disciplines [51].
\nIn the
In the
In summary, we reason that during the fluid phase, firms need to develop large and diverse technology portfolios to cope with uncertainty and to keep development options open. In later phases, after a dominant design appears and technological uncertainty is lower, firms will benefit more from smaller, specialized portfolios that can be more easily protected and exploited. Based on this reasoning, we formulate the following hypotheses:
\nWe test our hypotheses in the ASIC industry because it is knowledge-intensive, technology-intensive, and dynamic [11]. This makes it possible to measure the impact of the size and diversity of the internal technology portfolio on the innovative performance of ASIC firms during the phases of ASIC technology evolution.
\nWe constructed a panel dataset that includes data from 300 ASIC firms and selected all 67 ASIC firms with innovative performance from this dataset for the period 1986–2003, using the Integrated Circuit Engineering ASIC-Outlook industry reports (1986–1999) and the Integrated Circuit Engineering status reports (1980–1999) until 1999. For the period between 2000 and 2003, we used the IC Insights reports [53], Compustat, product guides, Gartner reports, and data of the World Semiconductor Trade Statistics Corporation. We selected these firms based on the available data from the Integrated Circuit Engineering Corporation and IC Insights Company.
\nTo measure our dependent variable, innovative performance, we collected data on the number of ASIC patents during 1986–2003 at t = i (where i = 1986, 1987, … 2003). Figure 4 shows an example of a firm’s innovative performance over time.
\nExample innovative performance.
We measured the first independent variable, the size of a firm’s technology portfolio, by collecting data on the number of successful ASIC patent applications measured at t = i minus 5 (where i = 1986, 1987, … 2003). We added all submarket-related patents per segment (PLD + gate array + standard cell) in 5 years prior to the year of observation. Henderson and Cockburn [54] recommend this moving window of 5 years, arguing that prior technologies can be expected to contribute to the development of new technologies. Figure 5 shows an example of a firm’s technology portfolio size over time.
\nExample technology portfolio size.
We measured the second independent variable, the diversity of a firm’s technology portfolio, by collecting data on the types of ASIC patents (PLD, gate array, standard cell) and by adding up all three submarket-related patents that a firm received during 5 years prior to the year of observation. This diversity is based on three types of technologies (PLD, gate array, standard cell) that the portfolios may contain in each year, which means that the value of this variable varies between 0 and 3: 0 if a firm has zero technologies in a year, 1 if a firm has one ASIC technology in its portfolios, etc. Figure 6 shows an example of a firm’s technology portfolio diversity over time.
\nExample technology portfolio diversity.
We measured the moderating variable, technology evolution, based on its three phases: the fluid phase between 1986 and 1991, the transitional phase between 1992 and 1997, and the specific phase between 1998 and 2003. We use an industry-level metric, which is in line with the framework of Abernathy and Utterback [9] and Utterback [24]. It is based on the technological developments of all firms together, starting with the first patents developed in the ASIC industry. The metric is the same across the three subsegments, PLD, gate array, and standard cell.
\nWe computed the interaction effect of technology portfolio size and technology evolution phase and the interaction effect of the technology portfolio diversity and technology evolution phase by multiplying the independent variables involved in the interaction. To enhance interpretability and eliminate nonessential multicollinearity, we standardized the independent variables in the interaction terms prior to computing those interaction terms [55]. We standardized the variables by first subtracting the overall mean from the value for each case, resulting in a mean of zero. We then divided the difference between the individual’s score and the mean by the standard deviation, which results in a standard deviation of one.
\nWe include five control variables. We measured the size of a firm’s strategic alliance network as the number of cooperative relationships between firms: a firm’s degree centrality [56]. We calculated this for each year using UCINET software. We use cooperation between firms over the last 5 years prior to the year of observation. We measured firm size as the natural log of the number of employees. Because larger firms are more dominant and have more financial means and resources to invest in R&D than smaller firms, they may have a higher innovation output compared to smaller firms due to economies of scale. We used a natural log because the number of employees is not normally distributed and the order of magnitude of the firm matters rather than its exact size. We used a firm’s R&D expenses as a percentage of total sales, to check for the firm’s propensity to invest in R&D. We also controlled for region indicating whether the firm’s headquarters are located in America, in Asia, or in Europe.
\nTable 1 gives an overview of the variables. The firm-level data show a high average R&D intensity of 13% and a high average of 590 ASIC patents in the firms’ portfolio, which indicate that the ASIC industry is knowledge-intensive and technology-intensive.
\nVariable | \nTime | \nDescription | \nMean | \nSD | \nMin. | \nMax. | \n
---|---|---|---|---|---|---|
Innovative performance | \nt = i | \nNumber of ASIC patents per year | \n151 | \n409 | \n0 | \n4764 | \n
Technology portfolio size | \nt = i − 5 | \nNumber of successful patent applications | \n590 | \n1592 | \n0 | \n19,454 | \n
Technology portfolio diversity | \nt = i − 5 | \nZero, one, two, or three types of ASIC patents (PLD, gate array, standard cell) in the technology portfolio | \n1.35 | \n1.24 | \n0 | \n3 | \n
Technology evolution | \nt = i | \n0 = fluid phase, 1 = transitional phase, 2 = specific phase | \n0.94 | \n0.81 | \n0 | \n2 | \n
Alliance network size | \nt = i − 5 | \nNormalized degree centrality | \n0.80 | \n0.84 | \n0 | \n5.3 | \n
Firm size | \nt = i | \nNatural log of the number of employees | \n8.81 | \n2.77 | \n2.30 | \n13.00 | \n
R&D/sales ratio | \nt = i | \nPercentage of sales invested in research and development | \n13% | \n15% | \n0% | \n300% | \n
Asia region | \nt = i | \nDummy variable denoting that the headquarters are located in Asia (default = America) | \n0.25 | \n0.43 | \n0 | \n1 | \n
Europe region | \nt = i | \nDummy variable denoting that the headquarters are located in Europe (default = America) | \n0.18 | \n0.38 | \n0 | \n1 | \n
Overview of the variables.
To test the hypotheses, we composed a longitudinal panel dataset. We conducted Hausman tests to decide whether to use fixed or random effect models. The panel analyses with the dependent count variable innovative performance are based on weighted patents. The mean and variance of the count distribution of these weighted patents are unequal, which means over-dispersion of the data, resulting in the need for a negative binomial regression [57].
\nTable 2 shows the correlation matrix. Based on the robustness of the test results (pair-wise exclusion of the variables with high correlations), no variables need to be excluded to avoid multicollinearity. Based on the results of the Hausman test, we selected fixed effects models for testing both hypotheses.
\n\n | Innovative performance | \nTechnology portfolio size | \nTechnology portfolio diversity | \nTechnology evolution phase | \nAlliance network size | \nFirm size | \nR&D/sales ratio | \nAsia region | \nEurope region | \n
---|---|---|---|---|---|---|---|---|---|
Innovative performance | \n1.00 | \n\n | \n | \n | \n | \n | \n | \n | \n |
Technology portfolio size | \n0.81 | \n1.00 | \n\n | \n | \n | \n | \n | \n | \n |
Technology portfolio diversity | \n0.32 | \n0.37 | \n1.00 | \n\n | \n | \n | \n | \n | \n |
Technology evolution | \n0.20 | \n0.31 | \n0.32 | \n1.00 | \n\n | \n | \n | \n | \n |
Alliance network size | \n0.22 | \n0.26 | \n0.46 | \n0.28 | \n1.00 | \n\n | \n | \n | \n |
Firm size | \n−0.00 | \n0.03 | \n0.42 | \n−0.02 | \n0.27 | \n1.00 | \n\n | \n | \n |
R&D/sales ratio | \n−0.01 | \n−0.00 | \n−0.11 | \n0.03 | \n−0.07 | \n−0.43 | \n1.00 | \n\n | \n |
Asia region | \n−0.06 | \n0.04 | \n0.27 | \n0.05 | \n−0.19 | \n0.35 | \n−0.27 | \n1.00 | \n\n |
Europe region | \n−0.14 | \n−0.14 | \n−0.09 | \n−0.03 | \n0.17 | \n0.31 | \n−0.05 | \n−0.25 | \n1.00 | \n
Correlations.
To check our hypotheses, we test three models, the results of which are presented in Table 3. Model 1 is the baseline model that tests the direct effects of technology portfolio size and technology portfolio diversity on innovative performance. The model indicates positive and significant effects of portfolio size and portfolio diversity on a firm’s innovative performance.
\n\n | Model 1 (main effects) | \nModel 2 (portfolio size and technology evolution) | \nModel 3 (portfolio diversity and technology evolution) | \n
---|---|---|---|
\n | Fixed effects♯♯ | \nFixed effects♯♯ | \nFixed effects♯♯ | \n
Technology portfolio size | \n0.000107*** (0.000) | \n0.000368*** (0.000) | \n0.000127*** (0.000) | \n
Technology portfolio diversity | \n0.726*** (0.109) | \n0.586*** (0.110) | \n0.675*** (0.107) | \n
Technology evolution phase | \n0.0403 (0.055) | \n−0.0056 (0.054) | \n0.274*** (0.071) | \n
Technology portfolio size x technology evolution phase ♯ | \n\n | −0.357*** (0.036) | \n\n |
Technology portfolio diversity x technology evolution phase ♯ | \n\n | \n | −0.276*** (0.054) | \n
Alliance network size | \n0.356*** (0.055) | \n0.350*** (0.054) | \n0.358*** (0.055) | \n
Firm size | \n0.146*** (0.032) | \n0.164*** (0.032) | \n0.183*** (0.034) | \n
R&D/sales ratio | \n−0.0162 (0.411) | \n0.065 (0.416) | \n0.0646 (0.408) | \n
Asia region | \n0.772*** (0.147) | \n0.788*** (0.149) | \n0.763*** (0.147) | \n
Europe region | \n−0.625*** (0.195) | \n−0.619*** (0.198) | \n−0.768*** (0.197) | \n
Constant | \n−3.315*** (0.311) | \n−3.435*** (0.314) | \n−3.776*** (0.334) | \n
Number of observations | \n807 | \n807 | \n807 | \n
Number of firms | \n59 | \n59 | \n59 | \n
Results.
To calculate the interaction terms, we standardized the variables. For the main effects, the variables are not standardized.
The values of the Hausman test are for Model 1 Prob > χ2 = 0.0042, for Model 2 Prob > χ2 = 0.0001, and for Model 3 Prob > χ2 = 0.0000. Since the tests are significant (p < 0.05), the null hypothesis is rejected, and the fixed effects model is most appropriate.
Standard errors in parentheses. Significance levels: ***p < 0.01, **p < 0.05, *p < 0.1.
Model 2 tests how the technology evolution stage influences the relationship between technology portfolio
Model 3 tests how the technology evolution stage influences the relationship between technology portfolio
All models indicate that larger firms and firms with larger networks have higher innovative performance, which is in line with findings of Gopalakrishnan and Bierly [58]. Larger firms have larger knowledge bases, and firms with larger networks are able to attract more external knowledge, which can be complementary to internally developed technology. Given the positive and significant main effects, the effects of these two control variables are not surprising.
\nThe models also show that R&D investments, measured as the R&D/sales ratio, have nonsignificant effects on innovative performance. While this may seem surprising, there are various possible explanations. First, in our data, R&D investment is measured for all the firm’s technologies, not specifically for the ASIC technologies. Many of the firms in our dataset also develop non-ASIC technologies, so that only a part of their R&D investment is related to ASIC development. Second, the effects of R&D on performance have sometimes been found to be nonsignificant or curvilinear (e.g., [40]), and these effects are not captured in our model. Related to this, R&D spending is regarded as an input to the development of a technology portfolio and may therefore be subject to the efficiency of the “invention production function” that is not captured in our model.
\nFinally, the models show that relatively more innovative firms were located in Asia and relatively fewer in Europe between 1986 and 2003. Explanations for this are that more ASIC-developing firms are based in Asia and fewer in Europe to begin with and that during this period some European firms exited the sector, whereas in Asia new players entered.
\nThe main effect of
We find that technology evolution negatively and significantly moderates the relationship between technology portfolio size and innovative performance. This is a possible explanation for the previous conflicting results of Lin et al. [39] and Artz et al. [32]. Our results indicate that it is more beneficial for a firm to have a relatively large portfolio in an earlier phase of technology evolution and to reduce the size of its portfolio in later phases. To put it differently, in the earlier phases, firms are more focused on production of knowledge from R&D, whereas in later phases, they are more focused on production of innovation from knowledge. Conducting cross-sectional research in an earlier phase would result in underestimating the production of innovations from R&D, while doing so in a later phase would result in overestimating the production of innovations from R&D.
\nIf we return to the characteristics of technological knowledge as we mentioned before, namely, economies of scale [3], indivisibilities [36], and self-generative abilities [37], firms likely need to accumulate a certain critical mass of technological knowledge in earlier phases before such knowledge becomes productive and leads to innovative performance. Conversely, in later phases, when such critical mass has been reached, it should be easier to achieve innovative performance, and expanding the technology portfolio is unnecessary.
\nOur findings for the
We find that technology evolution negatively and significantly moderates the relationship between technology portfolio diversity and innovative performance. This finding complements existing explanations of the complexity of the relationship between technology portfolio diversity and innovative performance. Our research indicates that it is beneficial for a firm to have a relatively diverse portfolio in earlier phases of technology evolution and to reduce portfolio diversity in later phases.
\nIt is widely recognized that this relationship is complex. Granstrand [3] argued that the coordination and integration costs of multidisciplinary R&D become higher with increased diversification. Research by Leten et al. [44] and Huang and Chen [45] confirms this argument. They found an inverted U-shaped effect of technological diversification on technological performance. While technological diversification enables combination and recombination, (too) high levels of diversification provide only marginal benefits due to high coordination and integration costs.
\nOur findings complement this explanation by arguing that more coordination efforts are needed in the earlier phases of technology evolution when technologies are unknown and that less coordination efforts are needed later when the relevant technologies are much better known. Therefore, we suggest that the inverted U-shape will have steeper slopes during earlier phases of technology evolution, when there are both high benefits from technology diversity and high costs of technology diversification. The inverted U-shape will have gentler slopes in later phases, when the benefits from technology diversity are less and the cost of technology diversification is lower.
\nWhether the firm can gain net benefits from the balance between technology diversity and coordination costs depends on the integrative capabilities of both technologists and managers [3]. If the firm possesses the capabilities to integrate diverse technologies, this is associated with causal ambiguity and sustainable competitive advantage [4].
\nThe relationships between the size and diversity of firms’ internal technology portfolios and their innovative performance are complex. We contribute to the literature by introducing technology evolution as a moderating variable of the relationship between internal technology sourcing and innovative performance. Our results support these moderating effects. The findings from our study contribute to explaining the complexity of the relationships between technology portfolio size and diversity and innovative performance by offering a possible explanation for conflicting empirical findings (technology portfolio size) and by offering an explanation that complements earlier findings (technology portfolio diversity).
\nOur findings suggest that during earlier phases of ASIC technology evolution, ASIC firms need broad technological portfolios and technological capabilities to keep their options open to adapt [2], to avoid lock-in [48], and to avoid investing in the wrong technology [49]. Such a broad portfolio requires strong integrative capabilities to profit from technology diversity. As such in earlier phases, causal ambiguity is created, making the firm’s innovation difficult to imitate. During later phases of ASIC technology evolution, ASIC firms need to focus on their core technologies and their core capabilities [52], in which the causal ambiguity has been embedded. In these phases, the role of integrative capabilities would be less pronounced.
\nFor managers in the ASIC industry, our results imply that they need to invest in a large and diverse technology portfolio in the early phase of technology evolution and need to maintain relatively smaller and less diverse technology portfolios later on, to optimize their firm’s innovative performance. Having a large and diverse ASIC portfolio in early phases of technology evolution gives the firm the flexibility to keep all options open during uncertain periods, while a smaller and specialized portfolio contributes to a focus on the core competencies in more certain periods. In the fluid phase, ASIC firms need to explore the technology space by developing a large and diverse technological knowledge portfolio. In the transitional phase, they need to reduce the size and diversity of their technological knowledge base and focus on their own unique knowledge contribution within the dominant design, applying knowledge from their core technological base. In the specific phase, they need to concentrate on a small, focused, unique, protectable, and exploitable technological knowledge base.
\nASIC technology is currently in the specific phase, and it therefore may make most sense for ASIC firms to focus on such a small, focused, unique, protectable, and exploitable technological knowledge base. As we argued in our discussion of the trends in the ASIC industry, they can do this by focusing on cost reduction and large-scale production of commodity products to earn back the ever-larger design and production investments or by focusing on providing added functionality solutions for specific high-end applications. Of course, while doing so, they need to separately manage their portfolios regarding emerging technologies. If they want to play an active role in such emerging technologies, they will need to develop large and diverse portfolios again to deal with the uncertainties that such technologies bring.
\nThe research described in this chapter has several limitations, which can provide directions for future research. First, we tested the effects of the size and diversity of the technology portfolio separately. We recognize that the combination of both effects may have an impact on innovative performance as well. Lin et al. [39] suggest that firms with smaller knowledge stocks should concentrate on a specific technological field and that the size of the knowledge stock may moderate the relationship between diversification and performance. This implies that, for individual firms, there may be different roads to success: either building large and diversified technology portfolios (e.g., Intel or Texas Instruments) or developing small and focused technology portfolios (e.g., SK Hynix). Future research could investigate the implications of technology evolution for both these roads, e.g., by case study analyses. Second, we did not specifically include the interactions between internal and external sourcing through the innovation network. The past research indicates complementarities between internal and external technology sourcing (e.g., [8, 50]). This implies that firms could, for example, combine internally focused portfolios with external cooperation to ensure the necessary diversity. Further research could extend out model to include such effects. Finally, we did not include the effects of mergers, acquisitions, buyouts, and spin-offs as vehicles to manage and build technology portfolios. This, too, could be addressed by future research using case study analyses.
\nIf you are associated with any of the institutions in our list below, you can apply to receive OA publication funds by following the instructions provided in the links.
",metaTitle:"List of Institutions by Country",metaDescription:"If you are associated with any of the institutions in our list below, you can apply to receive OA publication funds by following the instructions provided in the links. However, if your research is financed through any of the below-mentioned funders, please consult their Open Access policies or grant ‘terms and conditions’ to explore ways to cover your publication costs (also accessible by clicking on the link in their title).",metaKeywords:null,canonicalURL:"open-access-funding-institutions-list",contentRaw:'[{"type":"htmlEditorComponent","content":"Book Chapters and Monographs
\\n\\nBook Chapters
\\n\\nMonographs Only
\\n\\n\\n\\nBook Chapters and Monographs
\\n\\nMonographs Only
\\n\\nBook Chapters and Monographs
\\n\\n\\n\\nBook Chapters and Monographs
\\n\\n\\n\\nCorresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
\\n\\nCSIC affiliated authors can also take advantage of a central Open Access fund (amounting to 10,000 EUR) to cover up to 50% of the rest of the OAPF until it expires. Effective for chapters accepted from January 1, 2020.
\\n\\nCorresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
\\n\\nCorresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
\\n\\n\\n\\nCorresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
\\n\\nBook Chapters and Monographs
\\n\\nBook Chapters and Monographs
\\n\\nBook Chapters and Monographs
\\n\\nBook Chapters and Monographs
\\n\\nThe Claremont Colleges are pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
\\n\\nCorresponding authors will receive a 15% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
\\n\\nThe University of Massachusetts, Amherst is pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
\\n\\nCorresponding authors will receive a 10% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
\\n\\nThe University of Surrey is pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
\\n\\nCorresponding authors will receive a 10% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
\\n\\nMonographs Only
\\n\\n\\n\\nImportant: You must be a member or grantee of the above listed institutions in order to apply for their Open Access publication funds.
\\n"}]'},components:[{type:"htmlEditorComponent",content:'Book Chapters and Monographs
\n\n\n\nBook Chapters
\n\nMonographs Only
\n\n\n\nBook Chapters and Monographs
\n\nMonographs Only
\n\nBook Chapters and Monographs
\n\n\n\nBook Chapters and Monographs
\n\n\n\nCorresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
\n\nCSIC affiliated authors can also take advantage of a central Open Access fund (amounting to 10,000 EUR) to cover up to 50% of the rest of the OAPF until it expires. Effective for chapters accepted from January 1, 2020.
\n\nCorresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
\n\nCorresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
\n\n\n\nCorresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
\n\nBook Chapters and Monographs
\n\nBook Chapters and Monographs
\n\nBook Chapters and Monographs
\n\n\n\nBook Chapters and Monographs
\n\nThe Claremont Colleges are pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
\n\nCorresponding authors will receive a 15% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
\n\nThe University of Massachusetts, Amherst is pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
\n\nCorresponding authors will receive a 10% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
\n\nThe University of Surrey is pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
\n\nCorresponding authors will receive a 10% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
\n\nMonographs Only
\n\n\n\nImportant: You must be a member or grantee of the above listed institutions in order to apply for their Open Access publication funds.
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. In the Engineering side, Digital Signal Processing, Computer Architecture, Electronics Devices, Digital Filtering and Engineering Management.\nApart from his Academic Interest and activities he loves sport especially, Cricket, Football, Snooker and Squash. He plays cricket for Esbjerg city in the second division team as an opener wicket keeper batsman. He is a very good player of squash but has not played squash since his arrival in Denmark.",institutionString:null,institution:null},{id:"611",title:"Prof.",name:"T",middleName:null,surname:"Nagarajan",slug:"t-nagarajan",fullName:"T Nagarajan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universiti Teknologi Petronas",country:{name:"Malaysia"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:13404},{group:"region",caption:"Middle and South America",value:2,count:11681},{group:"region",caption:"Africa",value:3,count:4213},{group:"region",caption:"Asia",value:4,count:22423},{group:"region",caption:"Australia and Oceania",value:5,count:2020},{group:"region",caption:"Europe",value:6,count:33699}],offset:12,limit:12,total:135704},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{topicId:"20"},books:[{type:"book",id:"11857",title:"Updates on Excitons",subtitle:null,isOpenForSubmission:!0,hash:"8a2fd9bbbbae283bf115881d9d5cc47a",slug:null,bookSignature:"Dr. Ashim Kumar Dutta",coverURL:"https://cdn.intechopen.com/books/images_new/11857.jpg",editedByType:null,editors:[{id:"277477",title:"Dr.",name:"Ashim",surname:"Dutta",slug:"ashim-dutta",fullName:"Ashim Dutta"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11858",title:"Terahertz Radiation",subtitle:null,isOpenForSubmission:!0,hash:"f08ee0bf20cd8b5fa772b4752081f2fe",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11858.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11861",title:"Redefining Standard Model Particle Physics",subtitle:null,isOpenForSubmission:!0,hash:"085d4f6e00016fdad598675f825d6775",slug:null,bookSignature:"Prof. Brian Albert Robson",coverURL:"https://cdn.intechopen.com/books/images_new/11861.jpg",editedByType:null,editors:[{id:"102886",title:"Prof.",name:"Brian Albert",surname:"Robson",slug:"brian-albert-robson",fullName:"Brian Albert Robson"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12013",title:"Plasma Science - Recent Advances, New Perspectives and Applications",subtitle:null,isOpenForSubmission:!0,hash:"0261ac62d10563bf93735982748e3a2e",slug:null,bookSignature:"Dr. Sukhmander Singh",coverURL:"https://cdn.intechopen.com/books/images_new/12013.jpg",editedByType:null,editors:[{id:"282807",title:"Dr.",name:"Sukhmander",surname:"Singh",slug:"sukhmander-singh",fullName:"Sukhmander Singh"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12014",title:"Aerodynamics of Sports",subtitle:null,isOpenForSubmission:!0,hash:"a15f5d35a75d3dfee7d27e19238306b0",slug:null,bookSignature:"Dr. Rakhab Mehta",coverURL:"https://cdn.intechopen.com/books/images_new/12014.jpg",editedByType:null,editors:[{id:"56358",title:"Dr.",name:"Rakhab",surname:"Mehta",slug:"rakhab-mehta",fullName:"Rakhab Mehta"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12270",title:"Laser Ablation",subtitle:null,isOpenForSubmission:!0,hash:"998af2dd3ea1e28f4db7451a65010272",slug:null,bookSignature:"Dr. Masoud Harooni",coverURL:"https://cdn.intechopen.com/books/images_new/12270.jpg",editedByType:null,editors:[{id:"184282",title:"Dr.",name:"Masoud",surname:"Harooni",slug:"masoud-harooni",fullName:"Masoud Harooni"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:22},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:6},{group:"topic",caption:"Business, Management and Economics",value:7,count:4},{group:"topic",caption:"Chemistry",value:8,count:15},{group:"topic",caption:"Computer and Information Science",value:9,count:18},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:8},{group:"topic",caption:"Engineering",value:11,count:37},{group:"topic",caption:"Environmental Sciences",value:12,count:5},{group:"topic",caption:"Immunology and Microbiology",value:13,count:8},{group:"topic",caption:"Materials Science",value:14,count:15},{group:"topic",caption:"Mathematics",value:15,count:8},{group:"topic",caption:"Medicine",value:16,count:61},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:2},{group:"topic",caption:"Neuroscience",value:18,count:2},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:7},{group:"topic",caption:"Physics",value:20,count:5},{group:"topic",caption:"Psychology",value:21,count:5},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:8},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:2}],offset:12,limit:12,total:6},popularBooks:{featuredBooks:[{type:"book",id:"10827",title:"Oral Health Care",subtitle:"An Important Issue of the Modern Society",isOpenForSubmission:!1,hash:"9a0ceb9ced4598aea3f3723f6dc4ea04",slug:"oral-health-care-an-important-issue-of-the-modern-society",bookSignature:"Lavinia Cosmina Ardelean and Laura Cristina Rusu",coverURL:"https://cdn.intechopen.com/books/images_new/10827.jpg",editors:[{id:"180569",title:"Dr.",name:"Lavinia",middleName:null,surname:"Ardelean",slug:"lavinia-ardelean",fullName:"Lavinia Ardelean"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10780",title:"Current Trends in Orthodontics",subtitle:null,isOpenForSubmission:!1,hash:"badce0e23eb5176fd653b049d5295c0a",slug:"current-trends-in-orthodontics",bookSignature:"Farid Bourzgui",coverURL:"https://cdn.intechopen.com/books/images_new/10780.jpg",editors:[{id:"52177",title:"Prof.",name:"Farid",middleName:null,surname:"Bourzgui",slug:"farid-bourzgui",fullName:"Farid Bourzgui"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8452",title:"Organizational Conflict",subtitle:"New Insights",isOpenForSubmission:!1,hash:"96bdaaba38a7850a7e7379aa5a505748",slug:"organizational-conflict-new-insights",bookSignature:"Josiane Fahed-Sreih",coverURL:"https://cdn.intechopen.com/books/images_new/8452.jpg",editors:[{id:"103784",title:"Dr.",name:"Josiane",middleName:null,surname:"Fahed-Sreih",slug:"josiane-fahed-sreih",fullName:"Josiane Fahed-Sreih"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10206",title:"Terahertz Technology",subtitle:null,isOpenForSubmission:!1,hash:"2cdb79bf6297623f1d6202ef11f099c4",slug:"terahertz-technology",bookSignature:"Borwen You and Ja-Yu Lu",coverURL:"https://cdn.intechopen.com/books/images_new/10206.jpg",editors:[{id:"191131",title:"Dr.",name:"Borwen",middleName:null,surname:"You",slug:"borwen-you",fullName:"Borwen You"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11331",title:"Secondary Metabolites",subtitle:"Trends and Reviews",isOpenForSubmission:!1,hash:"7d6274f42d5441e537c5fa744bc84523",slug:"secondary-metabolites-trends-and-reviews",bookSignature:"Ramasamy Vijayakumar and Suresh Selvapuram Sudalaimuthu Raja",coverURL:"https://cdn.intechopen.com/books/images_new/11331.jpg",editors:[{id:"176044",title:"Dr.",name:"Ramasamy",middleName:null,surname:"Vijayakumar",slug:"ramasamy-vijayakumar",fullName:"Ramasamy Vijayakumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10793",title:"Molecular Mechanisms in Cancer",subtitle:null,isOpenForSubmission:!1,hash:"3ed2817275edb3de6f5683602314706e",slug:"molecular-mechanisms-in-cancer",bookSignature:"Metin Budak and Rajamanickam Rajkumar",coverURL:"https://cdn.intechopen.com/books/images_new/10793.jpg",editors:[{id:"226275",title:"Ph.D.",name:"Metin",middleName:null,surname:"Budak",slug:"metin-budak",fullName:"Metin Budak"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10957",title:"Liquid Crystals",subtitle:null,isOpenForSubmission:!1,hash:"7a2d81fa4893fcf74e7b3823a3e4f385",slug:"liquid-crystals",bookSignature:"Pankaj Kumar Choudhury and Abdel-Baset M.A. Ibrahim",coverURL:"https://cdn.intechopen.com/books/images_new/10957.jpg",editors:[{id:"205744",title:"Dr.",name:"Pankaj",middleName:null,surname:"Kumar Choudhury",slug:"pankaj-kumar-choudhury",fullName:"Pankaj Kumar Choudhury"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7827",title:"Interpersonal Relationships",subtitle:null,isOpenForSubmission:!1,hash:"ebf41f4d17c75010eb3294cc8cac3d47",slug:"interpersonal-relationships",bookSignature:"Martha Peaslee Levine",coverURL:"https://cdn.intechopen.com/books/images_new/7827.jpg",editors:[{id:"186919",title:"Dr.",name:"Martha",middleName:null,surname:"Peaslee Levine",slug:"martha-peaslee-levine",fullName:"Martha Peaslee Levine"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10652",title:"Information Extraction and Object Tracking in Digital Video",subtitle:null,isOpenForSubmission:!1,hash:"d13718b2d986d058d55cf91e69bf21c0",slug:"information-extraction-and-object-tracking-in-digital-video",bookSignature:"Antonio José Ribeiro Neves and Francisco Javier Gallegos-Funes",coverURL:"https://cdn.intechopen.com/books/images_new/10652.jpg",editors:[{id:"1177",title:"Prof.",name:"António",middleName:"J. R.",surname:"José Ribeiro Neves",slug:"antonio-jose-ribeiro-neves",fullName:"António José Ribeiro Neves"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10820",title:"Data Clustering",subtitle:null,isOpenForSubmission:!1,hash:"086d299ffd05aacd2311c3ca4ebf0d3a",slug:"data-clustering",bookSignature:"Niansheng Tang",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",editors:[{id:"221831",title:"Prof.",name:"Niansheng",middleName:null,surname:"Tang",slug:"niansheng-tang",fullName:"Niansheng Tang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10728",title:"Blood Groups",subtitle:"More than Inheritance of Antigenic Substances",isOpenForSubmission:!1,hash:"b5e79b54a382651f3130c9ee5ab862b4",slug:"blood-groups-more-than-inheritance-of-antigenic-substances",bookSignature:"Kaneez Fatima Shad",coverURL:"https://cdn.intechopen.com/books/images_new/10728.jpg",editors:[{id:"31988",title:"Prof.",name:"Kaneez",middleName:null,surname:"Fatima Shad",slug:"kaneez-fatima-shad",fullName:"Kaneez Fatima Shad"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4802},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"10827",title:"Oral Health Care",subtitle:"An Important Issue of the Modern Society",isOpenForSubmission:!1,hash:"9a0ceb9ced4598aea3f3723f6dc4ea04",slug:"oral-health-care-an-important-issue-of-the-modern-society",bookSignature:"Lavinia Cosmina Ardelean and Laura Cristina Rusu",coverURL:"https://cdn.intechopen.com/books/images_new/10827.jpg",publishedDate:"August 17th 2022",numberOfDownloads:2310,editors:[{id:"180569",title:"Dr.",name:"Lavinia",middleName:null,surname:"Ardelean",slug:"lavinia-ardelean",fullName:"Lavinia Ardelean"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",publishedDate:"August 17th 2022",numberOfDownloads:2095,editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10780",title:"Current Trends in Orthodontics",subtitle:null,isOpenForSubmission:!1,hash:"badce0e23eb5176fd653b049d5295c0a",slug:"current-trends-in-orthodontics",bookSignature:"Farid Bourzgui",coverURL:"https://cdn.intechopen.com/books/images_new/10780.jpg",publishedDate:"August 17th 2022",numberOfDownloads:2079,editors:[{id:"52177",title:"Prof.",name:"Farid",middleName:null,surname:"Bourzgui",slug:"farid-bourzgui",fullName:"Farid Bourzgui"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8452",title:"Organizational Conflict",subtitle:"New Insights",isOpenForSubmission:!1,hash:"96bdaaba38a7850a7e7379aa5a505748",slug:"organizational-conflict-new-insights",bookSignature:"Josiane Fahed-Sreih",coverURL:"https://cdn.intechopen.com/books/images_new/8452.jpg",publishedDate:"August 17th 2022",numberOfDownloads:1987,editors:[{id:"103784",title:"Dr.",name:"Josiane",middleName:null,surname:"Fahed-Sreih",slug:"josiane-fahed-sreih",fullName:"Josiane Fahed-Sreih"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10206",title:"Terahertz Technology",subtitle:null,isOpenForSubmission:!1,hash:"2cdb79bf6297623f1d6202ef11f099c4",slug:"terahertz-technology",bookSignature:"Borwen You and Ja-Yu Lu",coverURL:"https://cdn.intechopen.com/books/images_new/10206.jpg",publishedDate:"August 17th 2022",numberOfDownloads:1528,editors:[{id:"191131",title:"Dr.",name:"Borwen",middleName:null,surname:"You",slug:"borwen-you",fullName:"Borwen You"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11331",title:"Secondary Metabolites",subtitle:"Trends and Reviews",isOpenForSubmission:!1,hash:"7d6274f42d5441e537c5fa744bc84523",slug:"secondary-metabolites-trends-and-reviews",bookSignature:"Ramasamy Vijayakumar and Suresh Selvapuram Sudalaimuthu Raja",coverURL:"https://cdn.intechopen.com/books/images_new/11331.jpg",publishedDate:"August 17th 2022",numberOfDownloads:932,editors:[{id:"176044",title:"Dr.",name:"Ramasamy",middleName:null,surname:"Vijayakumar",slug:"ramasamy-vijayakumar",fullName:"Ramasamy Vijayakumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10793",title:"Molecular Mechanisms in Cancer",subtitle:null,isOpenForSubmission:!1,hash:"3ed2817275edb3de6f5683602314706e",slug:"molecular-mechanisms-in-cancer",bookSignature:"Metin Budak and Rajamanickam Rajkumar",coverURL:"https://cdn.intechopen.com/books/images_new/10793.jpg",publishedDate:"August 17th 2022",numberOfDownloads:700,editors:[{id:"226275",title:"Ph.D.",name:"Metin",middleName:null,surname:"Budak",slug:"metin-budak",fullName:"Metin Budak"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10957",title:"Liquid Crystals",subtitle:null,isOpenForSubmission:!1,hash:"7a2d81fa4893fcf74e7b3823a3e4f385",slug:"liquid-crystals",bookSignature:"Pankaj Kumar Choudhury and Abdel-Baset M.A. Ibrahim",coverURL:"https://cdn.intechopen.com/books/images_new/10957.jpg",publishedDate:"August 17th 2022",numberOfDownloads:676,editors:[{id:"205744",title:"Dr.",name:"Pankaj",middleName:null,surname:"Kumar Choudhury",slug:"pankaj-kumar-choudhury",fullName:"Pankaj Kumar Choudhury"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7827",title:"Interpersonal Relationships",subtitle:null,isOpenForSubmission:!1,hash:"ebf41f4d17c75010eb3294cc8cac3d47",slug:"interpersonal-relationships",bookSignature:"Martha Peaslee Levine",coverURL:"https://cdn.intechopen.com/books/images_new/7827.jpg",publishedDate:"July 27th 2022",numberOfDownloads:7215,editors:[{id:"186919",title:"Dr.",name:"Martha",middleName:null,surname:"Peaslee Levine",slug:"martha-peaslee-levine",fullName:"Martha Peaslee Levine"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10652",title:"Information Extraction and Object Tracking in Digital Video",subtitle:null,isOpenForSubmission:!1,hash:"d13718b2d986d058d55cf91e69bf21c0",slug:"information-extraction-and-object-tracking-in-digital-video",bookSignature:"Antonio José Ribeiro Neves and Francisco Javier Gallegos-Funes",coverURL:"https://cdn.intechopen.com/books/images_new/10652.jpg",publishedDate:"August 17th 2022",numberOfDownloads:602,editors:[{id:"1177",title:"Prof.",name:"António",middleName:"J. R.",surname:"José Ribeiro Neves",slug:"antonio-jose-ribeiro-neves",fullName:"António José Ribeiro Neves"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"8452",title:"Organizational Conflict",subtitle:"New Insights",isOpenForSubmission:!1,hash:"96bdaaba38a7850a7e7379aa5a505748",slug:"organizational-conflict-new-insights",bookSignature:"Josiane Fahed-Sreih",coverURL:"https://cdn.intechopen.com/books/images_new/8452.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"103784",title:"Dr.",name:"Josiane",middleName:null,surname:"Fahed-Sreih",slug:"josiane-fahed-sreih",fullName:"Josiane Fahed-Sreih"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10778",title:"Model-Based Control Engineering",subtitle:"Recent Design and Implementations for Varied Applications",isOpenForSubmission:!1,hash:"e39a567d9b6d2a45d0a1d927362c9005",slug:"model-based-control-engineering-recent-design-and-implementations-for-varied-applications",bookSignature:"Umar Zakir Abdul Hamid and Ahmad `Athif Mohd Faudzi",coverURL:"https://cdn.intechopen.com/books/images_new/10778.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"268173",title:"Dr.",name:"Umar Zakir Abdul",middleName:null,surname:"Hamid",slug:"umar-zakir-abdul-hamid",fullName:"Umar Zakir Abdul Hamid"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10780",title:"Current Trends in Orthodontics",subtitle:null,isOpenForSubmission:!1,hash:"badce0e23eb5176fd653b049d5295c0a",slug:"current-trends-in-orthodontics",bookSignature:"Farid Bourzgui",coverURL:"https://cdn.intechopen.com/books/images_new/10780.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"52177",title:"Prof.",name:"Farid",middleName:null,surname:"Bourzgui",slug:"farid-bourzgui",fullName:"Farid Bourzgui"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10793",title:"Molecular Mechanisms in Cancer",subtitle:null,isOpenForSubmission:!1,hash:"3ed2817275edb3de6f5683602314706e",slug:"molecular-mechanisms-in-cancer",bookSignature:"Metin Budak and Rajamanickam Rajkumar",coverURL:"https://cdn.intechopen.com/books/images_new/10793.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"226275",title:"Ph.D.",name:"Metin",middleName:null,surname:"Budak",slug:"metin-budak",fullName:"Metin Budak"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11308",title:"Selected Topics on Infant Feeding",subtitle:null,isOpenForSubmission:!1,hash:"213c3e403327a2919eca1dc5e82a0ec3",slug:"selected-topics-on-infant-feeding",bookSignature:"Isam Jaber AL-Zwaini and Haider Hadi AL-Musawi",coverURL:"https://cdn.intechopen.com/books/images_new/11308.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"30993",title:"Prof.",name:"Isam Jaber",middleName:null,surname:"Al-Zwaini",slug:"isam-jaber-al-zwaini",fullName:"Isam Jaber Al-Zwaini"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11331",title:"Secondary Metabolites",subtitle:"Trends and Reviews",isOpenForSubmission:!1,hash:"7d6274f42d5441e537c5fa744bc84523",slug:"secondary-metabolites-trends-and-reviews",bookSignature:"Ramasamy Vijayakumar and Suresh Selvapuram Sudalaimuthu Raja",coverURL:"https://cdn.intechopen.com/books/images_new/11331.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"176044",title:"Dr.",name:"Ramasamy",middleName:null,surname:"Vijayakumar",slug:"ramasamy-vijayakumar",fullName:"Ramasamy Vijayakumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10820",title:"Data Clustering",subtitle:null,isOpenForSubmission:!1,hash:"086d299ffd05aacd2311c3ca4ebf0d3a",slug:"data-clustering",bookSignature:"Niansheng Tang",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"221831",title:"Prof.",name:"Niansheng",middleName:null,surname:"Tang",slug:"niansheng-tang",fullName:"Niansheng Tang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10827",title:"Oral Health Care",subtitle:"An Important Issue of the Modern Society",isOpenForSubmission:!1,hash:"9a0ceb9ced4598aea3f3723f6dc4ea04",slug:"oral-health-care-an-important-issue-of-the-modern-society",bookSignature:"Lavinia Cosmina Ardelean and Laura Cristina Rusu",coverURL:"https://cdn.intechopen.com/books/images_new/10827.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"180569",title:"Dr.",name:"Lavinia",middleName:null,surname:"Ardelean",slug:"lavinia-ardelean",fullName:"Lavinia Ardelean"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11139",title:"Geochemistry and Mineral Resources",subtitle:null,isOpenForSubmission:!1,hash:"928cebbdce21d9b3f081267b24f12dfb",slug:"geochemistry-and-mineral-resources",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11139.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"297",title:"Animal Science",slug:"animal-science",parent:{id:"25",title:"Veterinary Medicine and Science",slug:"veterinary-medicine-and-science"},numberOfBooks:20,numberOfSeries:0,numberOfAuthorsAndEditors:510,numberOfWosCitations:405,numberOfCrossrefCitations:346,numberOfDimensionsCitations:704,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"297",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"10830",title:"Animal Feed Science and Nutrition",subtitle:"Production, Health and Environment",isOpenForSubmission:!1,hash:"79944fc8fbbaa329aed6fde388154832",slug:"animal-feed-science-and-nutrition-production-health-and-environment",bookSignature:"Amlan Kumar Patra",coverURL:"https://cdn.intechopen.com/books/images_new/10830.jpg",editedByType:"Edited by",editors:[{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11008",title:"Sheep Farming",subtitle:"Herds Husbandry, Management System, Reproduction and Improvement of Animal Health",isOpenForSubmission:!1,hash:"992f691327b36848b6e1137b70d921d5",slug:"sheep-farming-herds-husbandry-management-system-reproduction-and-improvement-of-animal-health",bookSignature:"Manuel Gonzalez Ronquillo and Carlos Palacios Riocerezo",coverURL:"https://cdn.intechopen.com/books/images_new/11008.jpg",editedByType:"Edited by",editors:[{id:"175967",title:"Dr.",name:"Manuel",middleName:null,surname:"Gonzalez Ronquillo",slug:"manuel-gonzalez-ronquillo",fullName:"Manuel Gonzalez Ronquillo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10751",title:"Bovine Science",subtitle:"Challenges and Advances",isOpenForSubmission:!1,hash:"9e3eb325f9fce20e6cefbce1c26d647a",slug:"bovine-science-challenges-and-advances",bookSignature:"Muhammad Abubakar",coverURL:"https://cdn.intechopen.com/books/images_new/10751.jpg",editedByType:"Edited by",editors:[{id:"112070",title:"Dr.",name:"Muhammad",middleName:null,surname:"Abubakar",slug:"muhammad-abubakar",fullName:"Muhammad Abubakar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10496",title:"Advanced Studies in the 21st Century Animal Nutrition",subtitle:null,isOpenForSubmission:!1,hash:"8ffe43a82ac48b309abc3632bbf3efd0",slug:"advanced-studies-in-the-21st-century-animal-nutrition",bookSignature:"László Babinszky, Juliana Oliveira and Edson Mauro Santos",coverURL:"https://cdn.intechopen.com/books/images_new/10496.jpg",editedByType:"Edited by",editors:[{id:"53998",title:"Prof.",name:"László",middleName:null,surname:"Babinszky",slug:"laszlo-babinszky",fullName:"László Babinszky"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8545",title:"Animal Reproduction in Veterinary Medicine",subtitle:null,isOpenForSubmission:!1,hash:"13aaddf5fdbbc78387e77a7da2388bf6",slug:"animal-reproduction-in-veterinary-medicine",bookSignature:"Faruk Aral, Rita Payan-Carreira and Miguel Quaresma",coverURL:"https://cdn.intechopen.com/books/images_new/8545.jpg",editedByType:"Edited by",editors:[{id:"25600",title:"Prof.",name:"Faruk",middleName:null,surname:"Aral",slug:"faruk-aral",fullName:"Faruk Aral"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8468",title:"Sheep Farming",subtitle:"An Approach to Feed, Growth and Health",isOpenForSubmission:!1,hash:"838f08594850bc04aa14ec873ed1b96f",slug:"sheep-farming-an-approach-to-feed-growth-and-health",bookSignature:"António Monteiro",coverURL:"https://cdn.intechopen.com/books/images_new/8468.jpg",editedByType:"Edited by",editors:[{id:"190314",title:"Prof.",name:"António",middleName:"Cardoso",surname:"Monteiro",slug:"antonio-monteiro",fullName:"António Monteiro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9081",title:"Equine Science",subtitle:null,isOpenForSubmission:!1,hash:"ac415ef2f5450fa80fdb9cf6cf32cd2d",slug:"equine-science",bookSignature:"Catrin Rutland and Albert Rizvanov",coverURL:"https://cdn.intechopen.com/books/images_new/9081.jpg",editedByType:"Edited by",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8460",title:"Reproductive Biology and Technology in Animals",subtitle:null,isOpenForSubmission:!1,hash:"32ef5fe73998dd723d308225d756fa1e",slug:"reproductive-biology-and-technology-in-animals",bookSignature:"Juan Carlos Gardón Poggi and Katy Satué Ambrojo",coverURL:"https://cdn.intechopen.com/books/images_new/8460.jpg",editedByType:"Edited by",editors:[{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón Poggi",slug:"juan-carlos-gardon-poggi",fullName:"Juan Carlos Gardón Poggi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8524",title:"Lactation in Farm Animals",subtitle:"Biology, Physiological Basis, Nutritional Requirements, and Modelization",isOpenForSubmission:!1,hash:"2aa2a9a0ec13040bbf0455e34625504e",slug:"lactation-in-farm-animals-biology-physiological-basis-nutritional-requirements-and-modelization",bookSignature:"Naceur M'Hamdi",coverURL:"https://cdn.intechopen.com/books/images_new/8524.jpg",editedByType:"Edited by",editors:[{id:"73376",title:"Dr.",name:"Naceur",middleName:null,surname:"M'Hamdi",slug:"naceur-m'hamdi",fullName:"Naceur M'Hamdi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8288",title:"Bacterial Cattle Diseases",subtitle:null,isOpenForSubmission:!1,hash:"f45b8b4974eb0d7de8719ef6b9146200",slug:"bacterial-cattle-diseases",bookSignature:"Hussein Abdel hay El-Sayed Kaoud",coverURL:"https://cdn.intechopen.com/books/images_new/8288.jpg",editedByType:"Edited by",editors:[{id:"265070",title:"Dr.",name:"Hussein Abdelhay",middleName:null,surname:"Essayed Kaoud",slug:"hussein-abdelhay-essayed-kaoud",fullName:"Hussein Abdelhay Essayed Kaoud"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6898",title:"Comparative Endocrinology of Animals",subtitle:null,isOpenForSubmission:!1,hash:"1c615706c8e4220ea5a24d231947ac7a",slug:"comparative-endocrinology-of-animals",bookSignature:"Edward Narayan",coverURL:"https://cdn.intechopen.com/books/images_new/6898.jpg",editedByType:"Edited by",editors:[{id:"259298",title:"Dr.",name:"Edward",middleName:null,surname:"Narayan",slug:"edward-narayan",fullName:"Edward Narayan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6993",title:"Bovine Science",subtitle:"A Key to Sustainable Development",isOpenForSubmission:!1,hash:"fe7bdc1a2e1aa960e1f51dae7c705002",slug:"bovine-science-a-key-to-sustainable-development",bookSignature:"Sadashiv S. O. and Sharangouda J. Patil",coverURL:"https://cdn.intechopen.com/books/images_new/6993.jpg",editedByType:"Edited by",editors:[{id:"176334",title:"Dr.",name:"Sadashiv",middleName:null,surname:"S. O.",slug:"sadashiv-s.-o.",fullName:"Sadashiv S. O."}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:20,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"39623",doi:"10.5772/50192",title:"Use of Yeast Probiotics in Ruminants: Effects and Mechanisms of Action on Rumen pH, Fibre Degradation, and Microbiota According to the Diet",slug:"use-of-yeast-probiotics-in-ruminants-effects-and-mechanisms-of-action-on-rumen-ph-fibre-degradation-",totalDownloads:7939,totalCrossrefCites:17,totalDimensionsCites:39,abstract:null,book:{id:"2991",slug:"probiotic-in-animals",title:"Probiotic in Animals",fullTitle:"Probiotic in Animals"},signatures:"Frédérique Chaucheyras-Durand, Eric Chevaux, Cécile Martin and Evelyne Forano",authors:[{id:"151065",title:"Dr.",name:"Frederique",middleName:null,surname:"Chaucheyras-Durand",slug:"frederique-chaucheyras-durand",fullName:"Frederique Chaucheyras-Durand"},{id:"151068",title:"Mr.",name:"Eric",middleName:null,surname:"Chevaux",slug:"eric-chevaux",fullName:"Eric Chevaux"},{id:"151069",title:"Dr.",name:"Evelyne",middleName:null,surname:"Forano",slug:"evelyne-forano",fullName:"Evelyne Forano"},{id:"160177",title:"Dr.",name:"Cécile",middleName:null,surname:"Martin",slug:"cecile-martin",fullName:"Cécile Martin"}]},{id:"16107",doi:"10.5772/16563",title:"Effect of Cryopreservation on Sperm Quality and Fertility",slug:"effect-of-cryopreservation-on-sperm-quality-and-fertility",totalDownloads:15485,totalCrossrefCites:10,totalDimensionsCites:35,abstract:null,book:{id:"185",slug:"artificial-insemination-in-farm-animals",title:"Artificial Insemination in Farm Animals",fullTitle:"Artificial Insemination in Farm Animals"},signatures:"Alemayehu Lemma",authors:[{id:"25594",title:"Dr.",name:"Alemayehu",middleName:null,surname:"Lemma",slug:"alemayehu-lemma",fullName:"Alemayehu Lemma"}]},{id:"57645",doi:"10.5772/intechopen.71780",title:"Antibiotics in Chilean Aquaculture: A Review",slug:"antibiotics-in-chilean-aquaculture-a-review",totalDownloads:1952,totalCrossrefCites:18,totalDimensionsCites:30,abstract:"Aquaculture in Chile has been practiced since the 1920s; however, it was not until the 1990s that aquaculture became an important sector here. Important species in Chilean aquaculture include salmonids, algae, mollusks, and turbot. Salmonids are the dominant species in Chilean aquaculture for both harvest volume and export value, their production reaching greater than 800-thousand tons in 2015. However, this growth has been accompanied by an increase in disease presence, requiring greater drug use to control. This increase in drug use is an environmental and public health concern for the authorities, the salmon industry itself, and the destination markets. In this chapter, we review the literature on drug use, antibiotic resistance, regulatory framework, and alternatives, with focus on Chile.",book:{id:"6179",slug:"antibiotic-use-in-animals",title:"Antibiotic Use in Animals",fullTitle:"Antibiotic Use in Animals"},signatures:"Ivonne Lozano, Nelson F. Díaz, Susana Muñoz and Carlos Riquelme",authors:[{id:"208847",title:"Dr.",name:"Ivonne",middleName:null,surname:"Lozano",slug:"ivonne-lozano",fullName:"Ivonne Lozano"},{id:"208895",title:"Dr.",name:"Nelson F.",middleName:null,surname:"Díaz",slug:"nelson-f.-diaz",fullName:"Nelson F. Díaz"},{id:"208897",title:"Dr.",name:"Carlos",middleName:null,surname:"Riquelme",slug:"carlos-riquelme",fullName:"Carlos Riquelme"},{id:"208898",title:"MSc.",name:"Susana",middleName:null,surname:"Muñoz",slug:"susana-munoz",fullName:"Susana Muñoz"}]},{id:"58486",doi:"10.5772/intechopen.72865",title:"Quality of Chicken Meat",slug:"quality-of-chicken-meat",totalDownloads:3354,totalCrossrefCites:20,totalDimensionsCites:29,abstract:"Chicken meat is considered as an easily available source of high-quality protein and other nutrients that are necessary for proper body functioning. In order to meet the consumers’ growing demands for high-quality protein, the poultry industry focused on selection of fast-growing broilers, which reach a body mass of about 2.5 kg within 6-week-intensive fattening. Relatively low sales prices of chicken meat, in comparison to other types of meat, speak in favor of the increased chicken meat consumption. In addition, chicken meat is known by its nutritional quality, as it contains significant amount of high-quality and easily digestible protein and a low portion of saturated fat. Therefore, chicken meat is recommended for consumption by all age groups. The technological parameters of chicken meat quality are related to various factors (keeping conditions, feeding treatment, feed composition, transport, stress before slaughter, etc.). Composition of chicken meat can be influenced through modification of chicken feed composition (addition of different types of oils, vitamins, microelements and amino acids), to produce meat enriched with functional ingredients (n-3 PUFA, carnosine, selenium and vitamin E). By this way, chicken meat becomes a foodstuff with added value, which, in addition to high-quality nutritional composition, also contains ingredients that are beneficial to human health.",book:{id:"6384",slug:"animal-husbandry-and-nutrition",title:"Animal Husbandry and Nutrition",fullTitle:"Animal Husbandry and Nutrition"},signatures:"Gordana Kralik, Zlata Kralik, Manuela Grčević and Danica Hanžek",authors:[{id:"207236",title:"Dr.",name:"Gordana",middleName:null,surname:"Kralik",slug:"gordana-kralik",fullName:"Gordana Kralik"},{id:"227281",title:"Prof.",name:"Zlata",middleName:null,surname:"Kralik",slug:"zlata-kralik",fullName:"Zlata Kralik"},{id:"227283",title:"Dr.",name:"Manuela",middleName:null,surname:"Grčević",slug:"manuela-grcevic",fullName:"Manuela Grčević"},{id:"227284",title:"BSc.",name:"Danica",middleName:null,surname:"Hanžek",slug:"danica-hanzek",fullName:"Danica Hanžek"}]},{id:"39624",doi:"10.5772/50320",title:"Dairy Propionibacteria: Less Conventional Probiotics to Improve the Human and Animal Health",slug:"dairy-propionibacteria-less-conventional-probiotics-to-improve-the-human-and-animal-health",totalDownloads:5805,totalCrossrefCites:11,totalDimensionsCites:24,abstract:null,book:{id:"2991",slug:"probiotic-in-animals",title:"Probiotic in Animals",fullTitle:"Probiotic in Animals"},signatures:"Gabriela Zárate",authors:[{id:"150953",title:"Dr.",name:"Gabriela",middleName:null,surname:"Zárate",slug:"gabriela-zarate",fullName:"Gabriela Zárate"}]}],mostDownloadedChaptersLast30Days:[{id:"56612",title:"Reproduction in Goats",slug:"reproduction-in-goats",totalDownloads:2933,totalCrossrefCites:3,totalDimensionsCites:4,abstract:"Reproductive activity of the goat begins when the females reach puberty, which happens at 5 months of age. The ovarian or estrous cycle is the period between two consecutive estrus. It is also the time that lasts the development of the follicle in the ovary, until rupture occurs and ovulation takes place, which coincides with the appearance of estrus. This chapter will describe the physiological and endocrinological bases of estrus in the goat. Likewise, factors affecting the presence of estrus and ovulation will be described. At another point, synchronization of estrus and ovulation, factors affecting the presence of estrus and external symptoms of estrus, will be described. To achieve synchronization of estrus or induction of ovulation within or outside the breeding season, it may be necessary to manage light hours, male effect, and/or use of hormones. The importance of artificial insemination is described, as well as the current situation of this technique worldwide. Currently, the techniques of artificial insemination in goats have been limited worldwide, due to the lack of resources of producers and trained technicians. The techniques of artificial insemination with estrous synchronization programs and ovulation with current research results will be described.",book:{id:"5987",slug:"goat-science",title:"Goat Science",fullTitle:"Goat Science"},signatures:"Fernando Sánchez Dávila, Alejandro Sergio del Bosque González\nand Hugo Bernal Barragán",authors:[{id:"201830",title:"Dr.",name:"Fernando",middleName:"Sanchez",surname:"Davila",slug:"fernando-davila",fullName:"Fernando Davila"},{id:"206127",title:"Dr.",name:"Alejandro Sergio",middleName:null,surname:"Del Bosque-Gonzalez",slug:"alejandro-sergio-del-bosque-gonzalez",fullName:"Alejandro Sergio Del Bosque-Gonzalez"},{id:"206128",title:"Dr.",name:"Hugo",middleName:null,surname:"Bernal-Barragán",slug:"hugo-bernal-barragan",fullName:"Hugo Bernal-Barragán"}]},{id:"58095",title:"The Innovative Techniques in Animal Husbandry",slug:"the-innovative-techniques-in-animal-husbandry",totalDownloads:3826,totalCrossrefCites:4,totalDimensionsCites:8,abstract:"Technology is developing rapidly. In this development, the transfer of computer systems and software to the application has made an important contribution. Technologic instruments made farmers can work more comfortable and increased animal production efficiency and profitability. Therefore, technologic developments are the main research area for animal productivity and sustainability. Many technologic equipment and tools made animal husbandry easier and comfortable. Especially management decisions and applications are effected highly ratio with this rapid development. In animal husbandry management decisions that need to be done daily are configured according to the correctness of the decisions to be made. At this point, smart systems give many opportunities to farmers. Milking, feeding, environmental control, reproductive performance constitute everyday jobs most affected by correct management decisions. Human errors in this works and decisions made big effect on last product quality and profitability are not able to be risked. This chapter deal with valuable information on the latest challenges and key innovations affecting the animal husbandry. Also, innovative approaches and applications for animal husbandry are tried to be summarized with detail latest research results.",book:{id:"6384",slug:"animal-husbandry-and-nutrition",title:"Animal Husbandry and Nutrition",fullTitle:"Animal Husbandry and Nutrition"},signatures:"Serap Göncü and Cahit Güngör",authors:[{id:"215579",title:"Prof.",name:"Serap",middleName:null,surname:"Goncu",slug:"serap-goncu",fullName:"Serap Goncu"},{id:"218971",title:"Dr.",name:"Cahit",middleName:null,surname:"Güngör",slug:"cahit-gungor",fullName:"Cahit Güngör"}]},{id:"58486",title:"Quality of Chicken Meat",slug:"quality-of-chicken-meat",totalDownloads:3354,totalCrossrefCites:19,totalDimensionsCites:29,abstract:"Chicken meat is considered as an easily available source of high-quality protein and other nutrients that are necessary for proper body functioning. In order to meet the consumers’ growing demands for high-quality protein, the poultry industry focused on selection of fast-growing broilers, which reach a body mass of about 2.5 kg within 6-week-intensive fattening. Relatively low sales prices of chicken meat, in comparison to other types of meat, speak in favor of the increased chicken meat consumption. In addition, chicken meat is known by its nutritional quality, as it contains significant amount of high-quality and easily digestible protein and a low portion of saturated fat. Therefore, chicken meat is recommended for consumption by all age groups. The technological parameters of chicken meat quality are related to various factors (keeping conditions, feeding treatment, feed composition, transport, stress before slaughter, etc.). Composition of chicken meat can be influenced through modification of chicken feed composition (addition of different types of oils, vitamins, microelements and amino acids), to produce meat enriched with functional ingredients (n-3 PUFA, carnosine, selenium and vitamin E). By this way, chicken meat becomes a foodstuff with added value, which, in addition to high-quality nutritional composition, also contains ingredients that are beneficial to human health.",book:{id:"6384",slug:"animal-husbandry-and-nutrition",title:"Animal Husbandry and Nutrition",fullTitle:"Animal Husbandry and Nutrition"},signatures:"Gordana Kralik, Zlata Kralik, Manuela Grčević and Danica Hanžek",authors:[{id:"207236",title:"Dr.",name:"Gordana",middleName:null,surname:"Kralik",slug:"gordana-kralik",fullName:"Gordana Kralik"},{id:"227281",title:"Prof.",name:"Zlata",middleName:null,surname:"Kralik",slug:"zlata-kralik",fullName:"Zlata Kralik"},{id:"227283",title:"Dr.",name:"Manuela",middleName:null,surname:"Grčević",slug:"manuela-grcevic",fullName:"Manuela Grčević"},{id:"227284",title:"BSc.",name:"Danica",middleName:null,surname:"Hanžek",slug:"danica-hanzek",fullName:"Danica Hanžek"}]},{id:"56453",title:"Goat System Productions: Advantages and Disadvantages to the Animal, Environment and Farmer",slug:"goat-system-productions-advantages-and-disadvantages-to-the-animal-environment-and-farmer",totalDownloads:4388,totalCrossrefCites:5,totalDimensionsCites:20,abstract:"Goats have always been considered very useful animals. Goats success is related to its excellent adaptability to the difficult mountain conditions, extreme weather and low value feed acceptance, versatile habits and high production considering their size. These are some reasons because goats are among the first animals to be domesticated. In terms of evolution, goats could be separated by their dispersion area in three large groups: the European, the Asian, and the African. Global goat populations, mainly in Africa and in Asia, have increased for centuries but very strongly in the past decades, well above the world population growth. They are also used for forest grazing, an integrated and alternative production system, very useful to control weed growth reducing fire risk. Despite some exceptions, no large‐scale effort to professionalize this industry has been made so far. There are consumers for goat dairy products and there is enough global production, but misses a professional network between both. Regarding goat meat, the world leadership also stays in Africa and Asia, namely in China, and there is a new phenomenon, the spreading of goat meat tradition through Europe due to migrants from Africa and other places with strong goat meat consumption.",book:{id:"5987",slug:"goat-science",title:"Goat Science",fullTitle:"Goat Science"},signatures:"António Monteiro, José Manuel Costa and Maria João Lima",authors:[{id:"190314",title:"Prof.",name:"António",middleName:"Cardoso",surname:"Monteiro",slug:"antonio-monteiro",fullName:"António Monteiro"},{id:"203680",title:"Prof.",name:"Maria João",middleName:null,surname:"Lima",slug:"maria-joao-lima",fullName:"Maria João Lima"},{id:"203683",title:"MSc.",name:"José Manuel",middleName:null,surname:"Costa",slug:"jose-manuel-costa",fullName:"José Manuel Costa"}]},{id:"70760",title:"Induction and Synchronization of Estrus",slug:"induction-and-synchronization-of-estrus",totalDownloads:1759,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"Estrus cycle is a rhythmic change that occur in the reproductive system of females starting from one estrus phase to another. The normal duration of estrus cycle is 21 days in cow, sow, and mare, 17 days in ewe, and 20 days in doe. The species which exhibit a single estrus cycle are known as monstrous and species which come into estrus twice or more are termed polyestrous animals. Among them some species have estrus cycles in a particular season and defined as seasonal polyestrous. It includes goats, sheep, and horses. On the other hand, cattle undergo estrus throughout the year. The estrus inducers can grossly be divided into two parts, that is, non-hormonal and hormonal. Non-hormonal treatments include plant-derived heat inducers, mineral supplementation, uterine and ovarian massage, and use of Lugol’s iodine. The hormones that are used in estrus induction are estrogen, progesterone, GnRH, prostaglandin, insulin, and anti-prolactin-based treatment. Synchronization can shorten the breeding period to less than 5 days, instead of females being bred over a 21-day period, depending on the treatment regimen. The combination of GnRH with the prostaglandin F2α (PGF2α)- and progesterone-based synchronization program has shown a novel direction in the estrus synchronization of cattle with the follicular development manipulation.",book:{id:"8545",slug:"animal-reproduction-in-veterinary-medicine",title:"Animal Reproduction in Veterinary Medicine",fullTitle:"Animal Reproduction in Veterinary Medicine"},signatures:"Prasanna Pal and Mohammad Rayees Dar",authors:[{id:"299126",title:"Dr.",name:"Mohammad Rayees",middleName:null,surname:"Dar",slug:"mohammad-rayees-dar",fullName:"Mohammad Rayees Dar"},{id:"311663",title:"Dr.",name:"Prasanna",middleName:null,surname:"Pal",slug:"prasanna-pal",fullName:"Prasanna Pal"}]}],onlineFirstChaptersFilter:{topicId:"297",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:11,numberOfPublishedChapters:91,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:333,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:11,numberOfPublishedChapters:144,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:126,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:23,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:13,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"August 17th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:33,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Rosa María Martínez-Espinosa is a Full Professor of Biochemistry and Molecular Biology at the University of Alicante, Spain, and has been the vice president of International Relations and Development Cooperation at this university since 2010. She created the research group in applied biochemistry in 2017 (https://web.ua.es/en/appbiochem/), and from 1999 to the present has made more than 200 contributions to Spanish and international conferences. Furthermore, she has around seventy-five scientific publications in indexed journals, eighty book chapters, and one patent to her credit. Her research work focuses on microbial metabolism (particularly on extremophile microorganisms), purification and characterization of enzymes with potential industrial and biotechnological applications, protocol optimization for genetically manipulating microorganisms, gene regulation characterization, carotenoid (pigment) production, and design and development of contaminated water and soil bioremediation processes by means of microorganisms. This research has received competitive public grants from the European Commission, the Spanish Ministry of Economy and Competitiveness, the Valencia Region Government, and the University of Alicante.",institutionString:"University of Alicante",institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:45,paginationItems:[{id:"83122",title:"New Perspectives on the Application of Chito-Oligosaccharides Derived from Chitin and Chitosan: A Review",doi:"10.5772/intechopen.106501",signatures:"Paul Edgardo Regalado-Infante, Norma Gabriela Rojas-Avelizapa, Rosalía Núñez-Pastrana, Daniel Tapia-Maruri, Andrea Margarita Rivas-Castillo, Régulo Carlos Llarena-Hernández and Luz Irene Rojas-Avelizapa",slug:"new-perspectives-on-the-application-of-chito-oligosaccharides-derived-from-chitin-and-chitosan-a-rev",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chitin-Chitosan - Isolation, Properties, and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11670.jpg",subseries:{id:"15",title:"Chemical Biology"}}},{id:"83015",title:"Acute Changes in Lipoprotein-Associated Oxidative Stress",doi:"10.5772/intechopen.106489",signatures:"Ngoc-Anh Le",slug:"acute-changes-in-lipoprotein-associated-oxidative-stress",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Anh",surname:"Le"}],book:{title:"Importance of Oxidative Stress and Antioxidant System in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/11671.jpg",subseries:{id:"15",title:"Chemical Biology"}}},{id:"83041",title:"Responses of Endoplasmic Reticulum to Plant Stress",doi:"10.5772/intechopen.106590",signatures:"Vishwa Jyoti Baruah, Bhaswati Sarmah, Manny Saluja and Elizabeth H. Mahood",slug:"responses-of-endoplasmic-reticulum-to-plant-stress",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"82914",title:"Glance on the Critical Role of IL-23 Receptor Gene Variations in Inflammation-Induced Carcinogenesis",doi:"10.5772/intechopen.105049",signatures:"Mohammed El-Gedamy",slug:"glance-on-the-critical-role-of-il-23-receptor-gene-variations-in-inflammation-induced-carcinogenesis",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}}]},overviewPagePublishedBooks:{paginationCount:33,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. Waisundara",profilePictureURL:"https://mts.intechopen.com/storage/users/194281/images/system/194281.jpg",biography:"Dr. Viduranga Waisundara obtained her Ph.D. in Food Science\nand Technology from the Department of Chemistry, National\nUniversity of Singapore, in 2010. She was a lecturer at Temasek Polytechnic, Singapore from July 2009 to March 2013.\nShe relocated to her motherland of Sri Lanka and spearheaded the Functional Food Product Development Project at the\nNational Institute of Fundamental Studies from April 2013 to\nOctober 2016. She was a senior lecturer on a temporary basis at the Department of\nFood Technology, Faculty of Technology, Rajarata University of Sri Lanka. She is\ncurrently Deputy Principal of the Australian College of Business and Technology –\nKandy Campus, Sri Lanka. She is also the Global Harmonization Initiative (GHI)",institutionString:"Australian College of Business & Technology",institution:{name:"Kobe College",institutionURL:null,country:{name:"Japan"}}}]},{type:"book",id:"6820",title:"Keratin",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6820.jpg",slug:"keratin",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Miroslav Blumenberg",hash:"6def75cd4b6b5324a02b6dc0359896d0",volumeInSeries:2,fullTitle:"Keratin",editors:[{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}}]},{type:"book",id:"7978",title:"Vitamin A",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7978.jpg",slug:"vitamin-a",publishedDate:"May 15th 2019",editedByType:"Edited by",bookSignature:"Leila Queiroz Zepka, Veridiana Vera de Rosso and Eduardo Jacob-Lopes",hash:"dad04a658ab9e3d851d23705980a688b",volumeInSeries:3,fullTitle:"Vitamin A",editors:[{id:"261969",title:"Dr.",name:"Leila",middleName:null,surname:"Queiroz Zepka",slug:"leila-queiroz-zepka",fullName:"Leila Queiroz Zepka",profilePictureURL:"https://mts.intechopen.com/storage/users/261969/images/system/261969.png",biography:"Prof. Dr. Leila Queiroz Zepka is currently an associate professor in the Department of Food Technology and Science, Federal University of Santa Maria, Brazil. She has more than fifteen years of teaching and research experience. She has published more than 550 scientific publications/communications, including 15 books, 50 book chapters, 100 original research papers, 380 research communications in national and international conferences, and 12 patents. She is a member of the editorial board of five journals and acts as a reviewer for several national and international journals. Her research interests include microalgal biotechnology with an emphasis on microalgae-based products.",institutionString:"Universidade Federal de Santa Maria",institution:{name:"Universidade Federal de Santa Maria",institutionURL:null,country:{name:"Brazil"}}}]},{type:"book",id:"7953",title:"Bioluminescence",subtitle:"Analytical Applications and Basic Biology",coverURL:"https://cdn.intechopen.com/books/images_new/7953.jpg",slug:"bioluminescence-analytical-applications-and-basic-biology",publishedDate:"September 25th 2019",editedByType:"Edited by",bookSignature:"Hirobumi Suzuki",hash:"3a8efa00b71abea11bf01973dc589979",volumeInSeries:4,fullTitle:"Bioluminescence - Analytical Applications and Basic Biology",editors:[{id:"185746",title:"Dr.",name:"Hirobumi",middleName:null,surname:"Suzuki",slug:"hirobumi-suzuki",fullName:"Hirobumi Suzuki",profilePictureURL:"https://mts.intechopen.com/storage/users/185746/images/system/185746.png",biography:"Dr. Hirobumi Suzuki received his Ph.D. in 1997 from Tokyo Metropolitan University, Japan, where he studied firefly phylogeny and the evolution of mating systems. He is especially interested in the genetic differentiation pattern and speciation process that correlate to the flashing pattern and mating behavior of some fireflies in Japan. He then worked for Olympus Corporation, a Japanese manufacturer of optics and imaging products, where he was involved in the development of luminescence technology and produced a bioluminescence microscope that is currently being used for gene expression analysis in chronobiology, neurobiology, and developmental biology. Dr. Suzuki currently serves as a visiting researcher at Kogakuin University, Japan, and also a vice president of the Japan Firefly Society.",institutionString:"Kogakuin University",institution:null}]}]},openForSubmissionBooks:{paginationCount:2,paginationItems:[{id:"11673",title:"Stem Cell Research",coverURL:"https://cdn.intechopen.com/books/images_new/11673.jpg",hash:"13092df328080c762dd9157be18ca38c",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 13th 2022",isOpenForSubmission:!0,editors:[{id:"203598",title:"Ph.D.",name:"Diana",surname:"Kitala",slug:"diana-kitala",fullName:"Diana Kitala"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12215",title:"Cell Death and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/12215.jpg",hash:"dfd456a29478fccf4ebd3294137eb1e3",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 29th 2022",isOpenForSubmission:!0,editors:[{id:"59529",title:"Dr.",name:"Ke",surname:"Xu",slug:"ke-xu",fullName:"Ke Xu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:21,paginationItems:[{id:"83115",title:"Fungi and Oomycetes–Allies in Eliminating Environmental Pathogens",doi:"10.5772/intechopen.106498",signatures:"Iasmina Luca",slug:"fungi-and-oomycetes-allies-in-eliminating-environmental-pathogens",totalDownloads:0,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Animal Welfare - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11579.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82991",title:"Diseases of the Canine Prostate Gland",doi:"10.5772/intechopen.105835",signatures:"Sabine Schäfer-Somi",slug:"diseases-of-the-canine-prostate-gland",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82956",title:"Potential Substitutes of Antibiotics for Swine and Poultry Production",doi:"10.5772/intechopen.106081",signatures:"Ho Trung Thong, Le Nu Anh Thu and Ho Viet Duc",slug:"potential-substitutes-of-antibiotics-for-swine-and-poultry-production",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Antibiotics and Probiotics in Animal Food - Impact and Regulation",coverURL:"https://cdn.intechopen.com/books/images_new/11578.jpg",subseries:{id:"20",title:"Animal Nutrition"}}},{id:"82905",title:"A Review of Application Strategies and Efficacy of Probiotics in Pet Food",doi:"10.5772/intechopen.105829",signatures:"Heather Acuff and Charles G. Aldrich",slug:"a-review-of-application-strategies-and-efficacy-of-probiotics-in-pet-food",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Antibiotics and Probiotics in Animal Food - Impact and Regulation",coverURL:"https://cdn.intechopen.com/books/images_new/11578.jpg",subseries:{id:"20",title:"Animal Nutrition"}}},{id:"82773",title:"Canine Transmissible Venereal Tumor: An Infectious Neoplasia in Dogs",doi:"10.5772/intechopen.106150",signatures:"Chanokchon Setthawongsin, Somporn Techangamsuwan and Anudep Rungsipipat",slug:"canine-transmissible-venereal-tumor-an-infectious-neoplasia-in-dogs",totalDownloads:17,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82797",title:"Anatomical Guide to the Paranasal Sinuses of Domestic Animals",doi:"10.5772/intechopen.106157",signatures:"Mohamed A.M. Alsafy, Samir A.A. El-Gendy and Catrin Sian Rutland",slug:"anatomical-guide-to-the-paranasal-sinuses-of-domestic-animals",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82457",title:"Canine Hearing Management",doi:"10.5772/intechopen.105515",signatures:"Peter M. Skip Scheifele, Devan Marshall, Stephen Lee, Paul Reid, Thomas McCreery and David Byrne",slug:"canine-hearing-management",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82285",title:"Parvovirus Vectors: The Future of Gene Therapy",doi:"10.5772/intechopen.105085",signatures:"Megha Gupta",slug:"parvovirus-vectors-the-future-of-gene-therapy",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82170",title:"Equine Stress: Neuroendocrine Physiology and Pathophysiology",doi:"10.5772/intechopen.105045",signatures:"Milomir Kovac, Tatiana Vladimirovna Ippolitova, Sergey Pozyabin, Ruslan Aliev, Viktoria Lobanova, Nevena Drakul and Catrin S. Rutland",slug:"equine-stress-neuroendocrine-physiology-and-pathophysiology",totalDownloads:34,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"81793",title:"Canine parvovirus-2: An Emerging Threat to Young Pets",doi:"10.5772/intechopen.104846",signatures:"Mithilesh Singh, Rajendran Manikandan, Ujjwal Kumar De, Vishal Chander, Babul Rudra Paul, Saravanan Ramakrishnan and Darshini Maramreddy",slug:"canine-parvovirus-2-an-emerging-threat-to-young-pets",totalDownloads:34,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}}]},subseriesFiltersForOFChapters:[{caption:"Animal Nutrition",value:20,count:3,group:"subseries"},{caption:"Animal Science",value:19,count:18,group:"subseries"}],publishedBooks:{paginationCount:11,paginationItems:[{type:"book",id:"10664",title:"Animal Reproduction",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10664.jpg",slug:"animal-reproduction",publishedDate:"May 25th 2022",editedByType:"Edited by",bookSignature:"Yusuf Bozkurt and Mustafa Numan Bucak",hash:"2d66af42fb17d0a6556bb9ef28e273c7",volumeInSeries:11,fullTitle:"Animal Reproduction",editors:[{id:"90846",title:"Prof.",name:"Yusuf",middleName:null,surname:"Bozkurt",slug:"yusuf-bozkurt",fullName:"Yusuf Bozkurt",profilePictureURL:"https://mts.intechopen.com/storage/users/90846/images/system/90846.jpg",institutionString:"İskenderun Technical University",institution:{name:"İskenderun Technical University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10830",title:"Animal Feed Science and Nutrition",subtitle:"Production, Health and Environment",coverURL:"https://cdn.intechopen.com/books/images_new/10830.jpg",slug:"animal-feed-science-and-nutrition-production-health-and-environment",publishedDate:"May 18th 2022",editedByType:"Edited by",bookSignature:"Amlan Kumar Patra",hash:"79944fc8fbbaa329aed6fde388154832",volumeInSeries:10,fullTitle:"Animal Feed Science and Nutrition - Production, Health and Environment",editors:[{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra",profilePictureURL:"https://mts.intechopen.com/storage/users/310962/images/system/310962.jpg",institutionString:null,institution:{name:"West Bengal University of Animal and Fishery Sciences",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8737",title:"Rabies Virus at the Beginning of 21st Century",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8737.jpg",slug:"rabies-virus-at-the-beginning-of-21st-century",publishedDate:"May 11th 2022",editedByType:"Edited by",bookSignature:"Sergey Tkachev",hash:"49cce3f548da548c718c865feb343509",volumeInSeries:9,fullTitle:"Rabies Virus at the Beginning of 21st Century",editors:[{id:"61139",title:"Dr.",name:"Sergey",middleName:null,surname:"Tkachev",slug:"sergey-tkachev",fullName:"Sergey Tkachev",profilePictureURL:"https://mts.intechopen.com/storage/users/61139/images/system/61139.png",institutionString:"Russian Academy of Sciences",institution:{name:"Russian Academy of Sciences",institutionURL:null,country:{name:"Russia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10496",title:"Advanced Studies in the 21st Century Animal Nutrition",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10496.jpg",slug:"advanced-studies-in-the-21st-century-animal-nutrition",publishedDate:"December 8th 2021",editedByType:"Edited by",bookSignature:"László Babinszky, Juliana Oliveira and Edson Mauro Santos",hash:"8ffe43a82ac48b309abc3632bbf3efd0",volumeInSeries:8,fullTitle:"Advanced Studies in the 21st Century Animal Nutrition",editors:[{id:"53998",title:"Prof.",name:"László",middleName:null,surname:"Babinszky",slug:"laszlo-babinszky",fullName:"László Babinszky",profilePictureURL:"https://mts.intechopen.com/storage/users/53998/images/system/53998.png",institutionString:"University of Debrecen",institution:{name:"University of Debrecen",institutionURL:null,country:{name:"Hungary"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10497",title:"Canine Genetics, Health and Medicine",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10497.jpg",slug:"canine-genetics-health-and-medicine",publishedDate:"June 2nd 2021",editedByType:"Edited by",bookSignature:"Catrin Rutland",hash:"b91512e31ce34032e560362e6cbccc1c",volumeInSeries:7,fullTitle:"Canine Genetics, Health and Medicine",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8545",title:"Animal Reproduction in Veterinary Medicine",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8545.jpg",slug:"animal-reproduction-in-veterinary-medicine",publishedDate:"January 20th 2021",editedByType:"Edited by",bookSignature:"Faruk Aral, Rita Payan-Carreira and Miguel Quaresma",hash:"13aaddf5fdbbc78387e77a7da2388bf6",volumeInSeries:6,fullTitle:"Animal Reproduction in Veterinary Medicine",editors:[{id:"25600",title:"Prof.",name:"Faruk",middleName:null,surname:"Aral",slug:"faruk-aral",fullName:"Faruk Aral",profilePictureURL:"https://mts.intechopen.com/storage/users/25600/images/system/25600.jpg",institutionString:"Independent Researcher",institution:{name:"Harran University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9081",title:"Equine Science",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9081.jpg",slug:"equine-science",publishedDate:"September 23rd 2020",editedByType:"Edited by",bookSignature:"Catrin Rutland and Albert Rizvanov",hash:"ac415ef2f5450fa80fdb9cf6cf32cd2d",volumeInSeries:5,fullTitle:"Equine Science",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8460",title:"Reproductive Biology and Technology in Animals",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8460.jpg",slug:"reproductive-biology-and-technology-in-animals",publishedDate:"April 15th 2020",editedByType:"Edited by",bookSignature:"Juan Carlos Gardón Poggi and Katy Satué Ambrojo",hash:"32ef5fe73998dd723d308225d756fa1e",volumeInSeries:4,fullTitle:"Reproductive Biology and Technology in Animals",editors:[{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón Poggi",slug:"juan-carlos-gardon-poggi",fullName:"Juan Carlos Gardón Poggi",profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",institutionString:null,institution:{name:"Valencia Catholic University Saint Vincent Martyr",institutionURL:null,country:{name:"Spain"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8524",title:"Lactation in Farm Animals",subtitle:"Biology, Physiological Basis, Nutritional Requirements, and Modelization",coverURL:"https://cdn.intechopen.com/books/images_new/8524.jpg",slug:"lactation-in-farm-animals-biology-physiological-basis-nutritional-requirements-and-modelization",publishedDate:"January 22nd 2020",editedByType:"Edited by",bookSignature:"Naceur M'Hamdi",hash:"2aa2a9a0ec13040bbf0455e34625504e",volumeInSeries:3,fullTitle:"Lactation in Farm Animals - Biology, Physiological Basis, Nutritional Requirements, and Modelization",editors:[{id:"73376",title:"Dr.",name:"Naceur",middleName:null,surname:"M'Hamdi",slug:"naceur-m'hamdi",fullName:"Naceur M'Hamdi",profilePictureURL:"https://mts.intechopen.com/storage/users/73376/images/system/73376.jpg",institutionString:null,institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7144",title:"Veterinary Anatomy and Physiology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7144.jpg",slug:"veterinary-anatomy-and-physiology",publishedDate:"March 13th 2019",editedByType:"Edited by",bookSignature:"Catrin Sian Rutland and Valentina Kubale",hash:"75cdacb570e0e6d15a5f6e69640d87c9",volumeInSeries:2,fullTitle:"Veterinary Anatomy and Physiology",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7233",title:"New Insights into Theriogenology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7233.jpg",slug:"new-insights-into-theriogenology",publishedDate:"December 5th 2018",editedByType:"Edited by",bookSignature:"Rita Payan-Carreira",hash:"74f4147e3fb214dd050e5edd3aaf53bc",volumeInSeries:1,fullTitle:"New Insights into Theriogenology",editors:[{id:"38652",title:"Prof.",name:"Rita",middleName:null,surname:"Payan-Carreira",slug:"rita-payan-carreira",fullName:"Rita Payan-Carreira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRiFPQA0/Profile_Picture_1614601496313",institutionString:null,institution:{name:"University of Évora",institutionURL:null,country:{name:"Portugal"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Animal Nutrition",value:20,count:2},{group:"subseries",caption:"Animal Reproductive Biology and Technology",value:28,count:4},{group:"subseries",caption:"Animal Science",value:19,count:5}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:3},{group:"publicationYear",caption:"2021",value:2021,count:3},{group:"publicationYear",caption:"2020",value:2020,count:3},{group:"publicationYear",caption:"2019",value:2019,count:1},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:755,paginationItems:[{id:"310674",title:"Dr.",name:"Pravin",middleName:null,surname:"Kendrekar",slug:"pravin-kendrekar",fullName:"Pravin Kendrekar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/310674/images/system/310674.jpg",biography:"Dr. Pravin Kendrekar, MSc, MBA, Ph.D., is currently a visiting scientist at the Lipid Nanostructure Laboratory, University of Central Lancashire, England. He previously worked as a post-doctoral fellow at the Ben-Gurion University of Negev, Israel; University of the Free State, South Africa; and Central University of Technology Bloemfontein, South Africa. He obtained his Ph.D. in Organic Chemistry from Nagaoka University of Technology, Japan. He has published more than seventy-four journal articles and attended several national and international conferences as speaker and chair. Dr. Kendrekar has received many international awards. He has several funded projects, namely, anti-malaria drug development, MRSA, and SARS-CoV-2 activity of curcumin and its formulations. He has filed four patents in collaboration with the University of Central Lancashire and Mayo Clinic Infectious Diseases. His present research includes organic synthesis, drug discovery and development, biochemistry, nanoscience, and nanotechnology.",institutionString:"Visiting Scientist at Lipid Nanostructures Laboratory, Centre for Smart Materials, School of Natural Sciences, University of Central Lancashire",institution:null},{id:"428125",title:"Dr.",name:"Vinayak",middleName:null,surname:"Adimule",slug:"vinayak-adimule",fullName:"Vinayak Adimule",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/428125/images/system/428125.jpg",biography:"Dr. Vinayak Adimule, MSc, Ph.D., is a professor and dean of R&D, Angadi Institute of Technology and Management, India. He has 15 years of research experience as a senior research scientist and associate research scientist in R&D organizations. He has published more than fifty research articles as well as several book chapters. He has two Indian patents and two international patents to his credit. Dr. Adimule has attended, chaired, and presented papers at national and international conferences. He is a guest editor for Topics in Catalysis and other journals. He is also an editorial board member, life member, and associate member for many international societies and research institutions. His research interests include nanoelectronics, material chemistry, artificial intelligence, sensors and actuators, bio-nanomaterials, and medicinal chemistry.",institutionString:"Angadi Institute of Technology and Management",institution:null},{id:"284317",title:"Prof.",name:"Kantharaju",middleName:null,surname:"Kamanna",slug:"kantharaju-kamanna",fullName:"Kantharaju Kamanna",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284317/images/21050_n.jpg",biography:"Prof. K. Kantharaju has received Bachelor of science (PCM), master of science (Organic Chemistry) and Doctor of Philosophy in Chemistry from Bangalore University. He worked as a Executive Research & Development @ Cadila Pharmaceuticals Ltd, Ahmedabad. He received DBT-postdoc fellow @ Molecular Biophysics Unit, Indian Institute of Science, Bangalore under the supervision of Prof. P. Balaram, later he moved to NIH-postdoc researcher at Drexel University College of Medicine, Philadelphia, USA, after his return from postdoc joined NITK-Surthakal as a Adhoc faculty at department of chemistry. Since from August 2013 working as a Associate Professor, and in 2016 promoted to Profeesor in the School of Basic Sciences: Department of Chemistry and having 20 years of teaching and research experiences.",institutionString:null,institution:{name:"Rani Channamma University, Belagavi",country:{name:"India"}}},{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/158492/images/system/158492.jpeg",biography:"Prof. Dr. Yusuf Tutar conducts his research at the Hamidiye Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Division of Biochemistry, University of Health Sciences, Turkey. He is also a faculty member in the Molecular Oncology Program. He obtained his MSc and Ph.D. at Oregon State University and Texas Tech University, respectively. He pursued his postdoctoral studies at Rutgers University Medical School and the National Institutes of Health (NIH/NIDDK), USA. His research focuses on biochemistry, biophysics, genetics, molecular biology, and molecular medicine with specialization in the fields of drug design, protein structure-function, protein folding, prions, microRNA, pseudogenes, molecular cancer, epigenetics, metabolites, proteomics, genomics, protein expression, and characterization by spectroscopic and calorimetric methods.",institutionString:"University of Health Sciences",institution:null},{id:"180528",title:"Dr.",name:"Hiroyuki",middleName:null,surname:"Kagechika",slug:"hiroyuki-kagechika",fullName:"Hiroyuki Kagechika",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180528/images/system/180528.jpg",biography:"Hiroyuki Kagechika received his bachelor’s degree and Ph.D. in Pharmaceutical Sciences from the University of Tokyo, Japan, where he served as an associate professor until 2004. He is currently a professor at the Institute of Biomaterials and Bioengineering (IBB), Tokyo Medical and Dental University (TMDU). From 2010 to 2012, he was the dean of the Graduate School of Biomedical Science. Since 2012, he has served as the vice dean of the Graduate School of Medical and Dental Sciences. He has been the director of the IBB since 2020. Dr. Kagechika’s major research interests are the medicinal chemistry of retinoids, vitamins D/K, and nuclear receptors. He has developed various compounds including a drug for acute promyelocytic leukemia.",institutionString:"Tokyo Medical and Dental University",institution:{name:"Tokyo Medical and Dental University",country:{name:"Japan"}}},{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94311/images/system/94311.jpeg",biography:"Martins Emeje obtained a BPharm with distinction from Ahmadu Bello University, Nigeria, and an MPharm and Ph.D. from the University of Nigeria (UNN), where he received the best Ph.D. award and was enlisted as UNN’s “Face of Research.” He established the first nanomedicine center in Nigeria and was the pioneer head of the intellectual property and technology transfer as well as the technology innovation and support center. Prof. Emeje’s several international fellowships include the prestigious Raman fellowship. He has published more than 150 articles and patents. He is also the head of R&D at NIPRD and holds a visiting professor position at Nnamdi Azikiwe University, Nigeria. He has a postgraduate certificate in Project Management from Walden University, Minnesota, as well as a professional teaching certificate and a World Bank certification in Public Procurement. Prof. Emeje was a national chairman of academic pharmacists in Nigeria and the 2021 winner of the May & Baker Nigeria Plc–sponsored prize for professional service in research and innovation.",institutionString:"National Institute for Pharmaceutical Research and Development",institution:{name:"National Institute for Pharmaceutical Research and Development",country:{name:"Nigeria"}}},{id:"436430",title:"Associate Prof.",name:"Mesut",middleName:null,surname:"Işık",slug:"mesut-isik",fullName:"Mesut Işık",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/436430/images/19686_n.jpg",biography:null,institutionString:null,institution:{name:"Bilecik University",country:{name:"Turkey"}}},{id:"268659",title:"Ms.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/268659/images/8143_n.jpg",biography:"Dr. Zhan received his undergraduate and graduate training in the fields of preventive medicine and epidemiology and statistics at the West China University of Medical Sciences in China during 1989 to 1999. He received his post-doctoral training in oncology and cancer proteomics for two years at the Cancer Research Institute of Human Medical University in China. In 2001, he went to the University of Tennessee Health Science Center (UTHSC) in USA, where he was a post-doctoral researcher and focused on mass spectrometry and cancer proteomics. Then, he was appointed as an Assistant Professor of Neurology, UTHSC in 2005. He moved to the Cleveland Clinic in USA as a Project Scientist/Staff in 2006 where he focused on the studies of eye disease proteomics and biomarkers. He returned to UTHSC as an Assistant Professor of Neurology in the end of 2007, engaging in proteomics and biomarker studies of lung diseases and brain tumors, and initiating the studies of predictive, preventive, and personalized medicine (PPPM) in cancer. In 2010, he was promoted to Associate Professor of Neurology, UTHSC. Currently, he is a Professor at Xiangya Hospital of Central South University in China, Fellow of Royal Society of Medicine (FRSM), the European EPMA National Representative in China, Regular Member of American Association for the Advancement of Science (AAAS), European Cooperation of Science and Technology (e-COST) grant evaluator, Associate Editors of BMC Genomics, BMC Medical Genomics, EPMA Journal, and Frontiers in Endocrinology, Executive Editor-in-Chief of Med One. He has\npublished 116 peer-reviewed research articles, 16 book chapters, 2 books, and 2 US patents. His current main research interest focuses on the studies of cancer proteomics and biomarkers, and the use of modern omics techniques and systems biology for PPPM in cancer, and on the development and use of 2DE-LC/MS for the large-scale study of human proteoforms.",institutionString:null,institution:{name:"Xiangya Hospital Central South University",country:{name:"China"}}},{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",biography:"Dr. Rizwan Ahmad is a University Professor and Coordinator, Quality and Development, College of Medicine, Imam Abdulrahman bin Faisal University, Saudi Arabia. Previously, he was Associate Professor of Human Function, Oman Medical College, Oman, and SBS University, Dehradun. Dr. Ahmad completed his education at Aligarh Muslim University, Aligarh. He has published several articles in peer-reviewed journals, chapters, and edited books. His area of specialization is free radical biochemistry and autoimmune diseases.",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",country:{name:"Saudi Arabia"}}},{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",biography:"Farid A. Badria, Ph.D., is the recipient of several awards, including The World Academy of Sciences (TWAS) Prize for Public Understanding of Science; the World Intellectual Property Organization (WIPO) Gold Medal for best invention; Outstanding Arab Scholar, Kuwait; and the Khwarizmi International Award, Iran. He has 250 publications, 12 books, 20 patents, and several marketed pharmaceutical products to his credit. He continues to lead research projects on developing new therapies for liver, skin disorders, and cancer. Dr. Badria was listed among the world’s top 2% of scientists in medicinal and biomolecular chemistry in 2019 and 2020. He is a member of the Arab Development Fund, Kuwait; International Cell Research Organization–United Nations Educational, Scientific and Cultural Organization (ICRO–UNESCO), Chile; and UNESCO Biotechnology France",institutionString:"Mansoura University",institution:{name:"Mansoura University",country:{name:"Egypt"}}},{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",biography:"Dr. Singh received a BPharm (2003) and MPharm (2005) from Panjab University, Chandigarh, India, and a Ph.D. (2013) from Punjab Technical University (PTU), Jalandhar, India. He has more than sixteen years of teaching experience and has supervised numerous postgraduate and Ph.D. students. He has to his credit more than seventy papers in SCI- and SCOPUS-indexed journals, fifty-five conference proceedings, four books, six Best Paper Awards, and five projects from different government agencies. He is currently an editorial board member of eight international journals and a reviewer for more than fifty scientific journals. He received Top Reviewer and Excellent Peer Reviewer Awards from Publons in 2016 and 2017, respectively. He is also on the panel of The International Reviewer for reviewing research proposals for grants from the Royal Society. He also serves as a Publons Academy mentor and Bentham brand ambassador.",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",country:{name:"India"}}},{id:"142388",title:"Dr.",name:"Thiago",middleName:"Gomes",surname:"Gomes Heck",slug:"thiago-gomes-heck",fullName:"Thiago Gomes Heck",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/142388/images/7259_n.jpg",biography:null,institutionString:null,institution:{name:"Universidade Regional do Noroeste do Estado do Rio Grande do Sul",country:{name:"Brazil"}}},{id:"336273",title:"Assistant Prof.",name:"Janja",middleName:null,surname:"Zupan",slug:"janja-zupan",fullName:"Janja Zupan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/336273/images/14853_n.jpeg",biography:"Janja Zupan graduated in 2005 at the Department of Clinical Biochemistry (superviser prof. dr. Janja Marc) in the field of genetics of osteoporosis. Since November 2009 she is working as a Teaching Assistant at the Faculty of Pharmacy, Department of Clinical Biochemistry. In 2011 she completed part of her research and PhD work at Institute of Genetics and Molecular Medicine, University of Edinburgh. She finished her PhD entitled The influence of the proinflammatory cytokines on the RANK/RANKL/OPG in bone tissue of osteoporotic and osteoarthritic patients in 2012. From 2014-2016 she worked at the Institute of Biomedical Sciences, University of Aberdeen as a postdoctoral research fellow on UK Arthritis research project where she gained knowledge in mesenchymal stem cells and regenerative medicine. She returned back to University of Ljubljana, Faculty of Pharmacy in 2016. She is currently leading project entitled Mesenchymal stem cells-the keepers of tissue endogenous regenerative capacity facing up to aging of the musculoskeletal system funded by Slovenian Research Agency.",institutionString:null,institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"357453",title:"Dr.",name:"Radheshyam",middleName:null,surname:"Maurya",slug:"radheshyam-maurya",fullName:"Radheshyam Maurya",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/357453/images/16535_n.jpg",biography:null,institutionString:null,institution:{name:"University of Hyderabad",country:{name:"India"}}},{id:"418340",title:"Dr.",name:"Jyotirmoi",middleName:null,surname:"Aich",slug:"jyotirmoi-aich",fullName:"Jyotirmoi Aich",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038Ugi5QAC/Profile_Picture_2022-04-15T07:48:28.png",biography:"Biotechnologist with 15 years of research including 6 years of teaching experience. Demonstrated record of scientific achievements through consistent publication record (H index = 13, with 874 citations) in high impact journals such as Nature Communications, Oncotarget, Annals of Oncology, PNAS, and AJRCCM, etc. Strong research professional with a post-doctorate from ACTREC where I gained experimental oncology experience in clinical settings and a doctorate from IGIB where I gained expertise in asthma pathophysiology. A well-trained biotechnologist with diverse experience on the bench across different research themes ranging from asthma to cancer and other infectious diseases. An individual with a strong commitment and innovative mindset. Have the ability to work on diverse projects such as regenerative and molecular medicine with an overall mindset of improving healthcare.",institutionString:"DY Patil Deemed to Be University",institution:null},{id:"349288",title:"Prof.",name:"Soumya",middleName:null,surname:"Basu",slug:"soumya-basu",fullName:"Soumya Basu",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035QxIDQA0/Profile_Picture_2022-04-15T07:47:01.jpg",biography:"Soumya Basu, Ph.D., is currently working as an Associate Professor at Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India. With 16+ years of trans-disciplinary research experience in Drug Design, development, and pre-clinical validation; 20+ research article publications in journals of repute, 9+ years of teaching experience, trained with cross-disciplinary education, Dr. Basu is a life-long learner and always thrives for new challenges.\r\nHer research area is the design and synthesis of small molecule partial agonists of PPAR-γ in lung cancer. She is also using artificial intelligence and deep learning methods to understand the exosomal miRNA’s role in cancer metastasis. Dr. Basu is the recipient of many awards including the Early Career Research Award from the Department of Science and Technology, Govt. of India. She is a reviewer of many journals like Molecular Biology Reports, Frontiers in Oncology, RSC Advances, PLOS ONE, Journal of Biomolecular Structure & Dynamics, Journal of Molecular Graphics and Modelling, etc. She has edited and authored/co-authored 21 journal papers, 3 book chapters, and 15 abstracts. She is a Board of Studies member at her university. She is a life member of 'The Cytometry Society”-in India and 'All India Cell Biology Society”- in India.",institutionString:"Dr. D.Y. Patil Vidyapeeth, Pune",institution:{name:"Dr. D.Y. Patil Vidyapeeth, Pune",country:{name:"India"}}},{id:"354817",title:"Dr.",name:"Anubhab",middleName:null,surname:"Mukherjee",slug:"anubhab-mukherjee",fullName:"Anubhab Mukherjee",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y0000365PbRQAU/ProfilePicture%202022-04-15%2005%3A11%3A18.480",biography:"A former member of Laboratory of Nanomedicine, Brigham and Women’s Hospital, Harvard University, Boston, USA, Dr. Anubhab Mukherjee is an ardent votary of science who strives to make an impact in the lives of those afflicted with cancer and other chronic/acute ailments. He completed his Ph.D. from CSIR-Indian Institute of Chemical Technology, Hyderabad, India, having been skilled with RNAi, liposomal drug delivery, preclinical cell and animal studies. He pursued post-doctoral research at College of Pharmacy, Health Science Center, Texas A & M University and was involved in another postdoctoral research at Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute, Santa Monica, California. In 2015, he worked in Harvard-MIT Health Sciences & Technology as a visiting scientist. He has substantial experience in nanotechnology-based formulation development and successfully served various Indian organizations to develop pharmaceuticals and nutraceutical products. He is an inventor in many US patents and an author in many peer-reviewed articles, book chapters and books published in various media of international repute. Dr. Mukherjee is currently serving as Principal Scientist, R&D at Esperer Onco Nutrition (EON) Pvt. Ltd. and heads the Hyderabad R&D center of the organization.",institutionString:"Esperer Onco Nutrition Pvt Ltd.",institution:null},{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/319365/images/system/319365.png",biography:"Manash K. Paul is a scientist and Principal Investigator at the University of California Los Angeles. He has contributed significantly to the fields of stem cell biology, regenerative medicine, and lung cancer. His research focuses on various signaling processes involved in maintaining stem cell homeostasis during the injury-repair process, deciphering the lung stem cell niche, pulmonary disease modeling, immuno-oncology, and drug discovery. He is currently investigating the role of extracellular vesicles in premalignant lung cell migration and detecting the metastatic phenotype of lung cancer via artificial intelligence-based analyses of exosomal Raman signatures. Dr. Paul also works on spatial multiplex immunofluorescence-based tissue mapping to understand the immune repertoire in lung cancer. Dr. Paul has published in more than sixty-five peer-reviewed international journals and is highly cited. He is the recipient of many awards, including the UCLA Vice Chancellor’s award and the 2022 AAISCR-R Vijayalaxmi Award for Innovative Cancer Research. He is a senior member of the Institute of Electrical and Electronics Engineers (IEEE) and an editorial board member for several international journals.",institutionString:"University of California Los Angeles",institution:{name:"University of California Los Angeles",country:{name:"United States of America"}}},{id:"311457",title:"Dr.",name:"Júlia",middleName:null,surname:"Scherer Santos",slug:"julia-scherer-santos",fullName:"Júlia Scherer Santos",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311457/images/system/311457.jpg",biography:"Dr. Júlia Scherer Santos works in the areas of cosmetology, nanotechnology, pharmaceutical technology, beauty, and aesthetics. Dr. Santos also has experience as a professor of graduate courses. Graduated in Pharmacy, specialization in Cosmetology and Cosmeceuticals applied to aesthetics, specialization in Aesthetic and Cosmetic Health, and a doctorate in Pharmaceutical Nanotechnology. Teaching experience in Pharmacy and Aesthetics and Cosmetics courses. She works mainly on the following subjects: nanotechnology, cosmetology, pharmaceutical technology, aesthetics.",institutionString:"Universidade Federal de Juiz de Fora",institution:{name:"Universidade Federal de Juiz de Fora",country:{name:"Brazil"}}},{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",biography:"Dr. Kükürt graduated from Uludağ University in Turkey. He started his academic career as a Research Assistant in the Department of Biochemistry at Kafkas University. In 2019, he completed his Ph.D. program in the Department of Biochemistry at the Institute of Health Sciences. He is currently working at the Department of Biochemistry, Kafkas University. He has 27 published research articles in academic journals, 11 book chapters, and 37 papers. He took part in 10 academic projects. He served as a reviewer for many articles. He still serves as a member of the review board in many academic journals. He is currently working on the protective activity of phenolic compounds in disorders associated with oxidative stress and inflammation.",institutionString:null,institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"178366",title:"Dr.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",biography:"Volkan Gelen is a Physiology specialist who received his veterinary degree from Kafkas University in 2011. Between 2011-2015, he worked as an assistant at Atatürk University, Faculty of Veterinary Medicine, Department of Physiology. In 2016, he joined Kafkas University, Faculty of Veterinary Medicine, Department of Physiology as an assistant professor. Dr. Gelen has been engaged in various academic activities at Kafkas University since 2016. There he completed 5 projects and has 3 ongoing projects. He has 60 articles published in scientific journals and 20 poster presentations in scientific congresses. His research interests include physiology, endocrine system, cancer, diabetes, cardiovascular system diseases, and isolated organ bath system studies.",institutionString:"Kafkas University",institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"418963",title:"Dr.",name:"Augustine Ododo",middleName:"Augustine",surname:"Osagie",slug:"augustine-ododo-osagie",fullName:"Augustine Ododo Osagie",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/418963/images/16900_n.jpg",biography:"Born into the family of Osagie, a prince of the Benin Kingdom. I am currently an academic in the Department of Medical Biochemistry, University of Benin. Part of the duties are to teach undergraduate students and conduct academic research.",institutionString:null,institution:{name:"University of Benin",country:{name:"Nigeria"}}},{id:"192992",title:"Prof.",name:"Shagufta",middleName:null,surname:"Perveen",slug:"shagufta-perveen",fullName:"Shagufta Perveen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192992/images/system/192992.png",biography:"Prof. Shagufta Perveen is a Distinguish Professor in the Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Dr. Perveen has acted as the principal investigator of major research projects funded by the research unit of King Saud University. She has more than ninety original research papers in peer-reviewed journals of international repute to her credit. She is a fellow member of the Royal Society of Chemistry UK and the American Chemical Society of the United States.",institutionString:"King Saud University",institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"49848",title:"Dr.",name:"Wen-Long",middleName:null,surname:"Hu",slug:"wen-long-hu",fullName:"Wen-Long Hu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49848/images/system/49848.jpg",biography:"Wen-Long Hu is Chief of the Division of Acupuncture, Department of Chinese Medicine at Kaohsiung Chang Gung Memorial Hospital, as well as an adjunct associate professor at Fooyin University and Kaohsiung Medical University. Wen-Long is President of Taiwan Traditional Chinese Medicine Medical Association. He has 28 years of experience in clinical practice in laser acupuncture therapy and 34 years in acupuncture. He is an invited speaker for lectures and workshops in laser acupuncture at many symposiums held by medical associations. He owns the patent for herbal preparation and producing, and for the supercritical fluid-treated needle. Dr. Hu has published three books, 12 book chapters, and more than 30 papers in reputed journals, besides serving as an editorial board member of repute.",institutionString:"Kaohsiung Chang Gung Memorial Hospital",institution:{name:"Kaohsiung Chang Gung Memorial Hospital",country:{name:"Taiwan"}}},{id:"298472",title:"Prof.",name:"Andrey V.",middleName:null,surname:"Grechko",slug:"andrey-v.-grechko",fullName:"Andrey V. Grechko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/298472/images/system/298472.png",biography:"Andrey Vyacheslavovich Grechko, Ph.D., Professor, is a Corresponding Member of the Russian Academy of Sciences. He graduated from the Semashko Moscow Medical Institute (Semashko National Research Institute of Public Health) with a degree in Medicine (1998), the Clinical Department of Dermatovenerology (2000), and received a second higher education in Psychology (2009). Professor A.V. Grechko held the position of Сhief Physician of the Central Clinical Hospital in Moscow. He worked as a professor at the faculty and was engaged in scientific research at the Medical University. Starting in 2013, he has been the initiator of the creation of the Federal Scientific and Clinical Center for Intensive Care and Rehabilitology, Moscow, Russian Federation, where he also serves as Director since 2015. He has many years of experience in research and teaching in various fields of medicine, is an author/co-author of more than 200 scientific publications, 13 patents, 15 medical books/chapters, including Chapter in Book «Metabolomics», IntechOpen, 2020 «Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology».",institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"199461",title:"Prof.",name:"Natalia V.",middleName:null,surname:"Beloborodova",slug:"natalia-v.-beloborodova",fullName:"Natalia V. Beloborodova",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/199461/images/system/199461.jpg",biography:'Natalia Vladimirovna Beloborodova was educated at the Pirogov Russian National Research Medical University, with a degree in pediatrics in 1980, a Ph.D. in 1987, and a specialization in Clinical Microbiology from First Moscow State Medical University in 2004. She has been a Professor since 1996. Currently, she is the Head of the Laboratory of Metabolism, a division of the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russian Federation. N.V. Beloborodova has many years of clinical experience in the field of intensive care and surgery. She studies infectious complications and sepsis. She initiated a series of interdisciplinary clinical and experimental studies based on the concept of integrating human metabolism and its microbiota. Her scientific achievements are widely known: she is the recipient of the Marie E. Coates Award \\"Best lecturer-scientist\\" Gustafsson Fund, Karolinska Institutes, Stockholm, Sweden, and the International Sepsis Forum Award, Pasteur Institute, Paris, France (2014), etc. Professor N.V. Beloborodova wrote 210 papers, five books, 10 chapters and has edited four books.',institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"354260",title:"Ph.D.",name:"Tércio Elyan",middleName:"Azevedo",surname:"Azevedo Martins",slug:"tercio-elyan-azevedo-martins",fullName:"Tércio Elyan Azevedo Martins",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/354260/images/16241_n.jpg",biography:"Graduated in Pharmacy from the Federal University of Ceará with the modality in Industrial Pharmacy, Specialist in Production and Control of Medicines from the University of São Paulo (USP), Master in Pharmaceuticals and Medicines from the University of São Paulo (USP) and Doctor of Science in the program of Pharmaceuticals and Medicines by the University of São Paulo. Professor at Universidade Paulista (UNIP) in the areas of chemistry, cosmetology and trichology. Assistant Coordinator of the Higher Course in Aesthetic and Cosmetic Technology at Universidade Paulista Campus Chácara Santo Antônio. Experience in the Pharmacy area, with emphasis on Pharmacotechnics, Pharmaceutical Technology, Research and Development of Cosmetics, acting mainly on topics such as cosmetology, antioxidant activity, aesthetics, photoprotection, cyclodextrin and thermal analysis.",institutionString:null,institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"334285",title:"Ph.D. Student",name:"Sameer",middleName:"Kumar",surname:"Jagirdar",slug:"sameer-jagirdar",fullName:"Sameer Jagirdar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334285/images/14691_n.jpg",biography:"I\\'m a graduate student at the center for biosystems science and engineering at the Indian Institute of Science, Bangalore, India. I am interested in studying host-pathogen interactions at the biomaterial interface.",institutionString:null,institution:{name:"Indian Institute of Science Bangalore",country:{name:"India"}}},{id:"329248",title:"Dr.",name:"Md. Faheem",middleName:null,surname:"Haider",slug:"md.-faheem-haider",fullName:"Md. Faheem Haider",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329248/images/system/329248.jpg",biography:"Dr. Md. Faheem Haider completed his BPharm in 2012 at Integral University, Lucknow, India. In 2014, he completed his MPharm with specialization in Pharmaceutics at Babasaheb Bhimrao Ambedkar University, Lucknow, India. He received his Ph.D. degree from Jamia Hamdard University, New Delhi, India, in 2018. He was selected for the GPAT six times and his best All India Rank was 34. Currently, he is an assistant professor at Integral University. Previously he was an assistant professor at IIMT University, Meerut, India. He has experience teaching DPharm, Pharm.D, BPharm, and MPharm students. He has more than five publications in reputed journals to his credit. Dr. Faheem’s research area is the development and characterization of nanoformulation for the delivery of drugs to various organs.",institutionString:"Integral University",institution:{name:"Integral University",country:{name:"India"}}},{id:"329795",title:"Dr.",name:"Mohd Aftab",middleName:"Aftab",surname:"Siddiqui",slug:"mohd-aftab-siddiqui",fullName:"Mohd Aftab Siddiqui",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329795/images/system/329795.png",biography:"Dr. Mohd Aftab Siddiqui is an assistant professor in the Faculty of Pharmacy, Integral University, Lucknow, India, where he obtained a Ph.D. in Pharmacology in 2020. He also obtained a BPharm and MPharm from the same university in 2013 and 2015, respectively. His area of research is the pharmacological screening of herbal drugs/natural products in liver cancer and cardiac diseases. He is a member of many professional bodies and has guided many MPharm and PharmD research projects. Dr. Siddiqui has many national and international publications and one German patent to his credit.",institutionString:"Integral University",institution:null}]}},subseries:{item:{id:"19",type:"subseries",title:"Animal Science",keywords:"Animal Science, Animal Biology, Wildlife Species, Domesticated Animals",scope:"The Animal Science topic welcomes research on captive and wildlife species, including domesticated animals. The research resented can consist of primary studies on various animal biology fields such as genetics, nutrition, behavior, welfare, and animal production, to name a few. Reviews on specialized areas of animal science are also welcome.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/19.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11415,editor:{id:"259298",title:"Dr.",name:"Edward",middleName:null,surname:"Narayan",slug:"edward-narayan",fullName:"Edward Narayan",profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",biography:"Dr. Edward Narayan graduated with Ph.D. degree in Biology from the University of the South Pacific and pioneered non-invasive reproductive and stress endocrinology tools for amphibians - the novel development and validation of non-invasive enzyme immunoassays for the evaluation of reproductive hormonal cycle and stress hormone responses to environmental stressors. \nDr. Narayan leads the Stress Lab (Comparative Physiology and Endocrinology) at the University of Queensland. A dynamic career research platform which is based on the thematic areas of comparative vertebrate physiology, stress endocrinology, reproductive endocrinology, animal health and welfare, and conservation biology. \nEdward has supervised 40 research students and published over 60 peer reviewed research.",institutionString:null,institution:{name:"University of Queensland",institutionURL:null,country:{name:"Australia"}}},editorTwo:null,editorThree:null,series:{id:"13",title:"Veterinary Medicine and Science",doi:"10.5772/intechopen.73681",issn:"2632-0517"},editorialBoard:[{id:"258334",title:"Dr.",name:"Carlos Eduardo",middleName:null,surname:"Fonseca-Alves",slug:"carlos-eduardo-fonseca-alves",fullName:"Carlos Eduardo Fonseca-Alves",profilePictureURL:"https://mts.intechopen.com/storage/users/258334/images/system/258334.jpg",institutionString:null,institution:{name:"Universidade Paulista",institutionURL:null,country:{name:"Brazil"}}},{id:"191123",title:"Dr.",name:"Juan José",middleName:null,surname:"Valdez-Alarcón",slug:"juan-jose-valdez-alarcon",fullName:"Juan José Valdez-Alarcón",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBfcQAG/Profile_Picture_1631354558068",institutionString:"Universidad Michoacana de San Nicolás de Hidalgo",institution:{name:"Universidad Michoacana de San Nicolás de Hidalgo",institutionURL:null,country:{name:"Mexico"}}},{id:"161556",title:"Dr.",name:"Maria Dos Anjos",middleName:null,surname:"Pires",slug:"maria-dos-anjos-pires",fullName:"Maria Dos Anjos Pires",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS8q2QAC/Profile_Picture_1633432838418",institutionString:null,institution:{name:"University of Trás-os-Montes and Alto Douro",institutionURL:null,country:{name:"Portugal"}}},{id:"209839",title:"Dr.",name:"Marina",middleName:null,surname:"Spinu",slug:"marina-spinu",fullName:"Marina Spinu",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRLXpQAO/Profile_Picture_1630044895475",institutionString:null,institution:{name:"University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca",institutionURL:null,country:{name:"Romania"}}},{id:"92185",title:"Dr.",name:"Sara",middleName:null,surname:"Savic",slug:"sara-savic",fullName:"Sara Savic",profilePictureURL:"https://mts.intechopen.com/storage/users/92185/images/system/92185.jfif",institutionString:'Scientific Veterinary Institute "Novi Sad"',institution:{name:'Scientific Veterinary Institute "Novi Sad"',institutionURL:null,country:{name:"Serbia"}}}]},onlineFirstChapters:{paginationCount:8,paginationItems:[{id:"83117",title:"Endothelial Secretome",doi:"10.5772/intechopen.106550",signatures:"Luiza Rusu",slug:"endothelial-secretome",totalDownloads:0,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Luiza",surname:"Rusu"}],book:{title:"Periodontology - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11566.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"83087",title:"Role of Cellular Responses in Periodontal Tissue Destruction",doi:"10.5772/intechopen.106645",signatures:"Nam Cong-Nhat Huynh",slug:"role-of-cellular-responses-in-periodontal-tissue-destruction",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Periodontology - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11566.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"82654",title:"Atraumatic Restorative Treatment: More than a Minimally Invasive Approach?",doi:"10.5772/intechopen.105623",signatures:"Manal A. Ablal",slug:"atraumatic-restorative-treatment-more-than-a-minimally-invasive-approach",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Caries - The Selection of Restoration Methods and Restorative Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11565.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"82735",title:"The Influence of Salivary pH on the Prevalence of Dental Caries",doi:"10.5772/intechopen.106154",signatures:"Laura-Cristina Rusu, Alexandra Roi, Ciprian-Ioan Roi, Codruta Victoria Tigmeanu and Lavinia Cosmina Ardelean",slug:"the-influence-of-salivary-ph-on-the-prevalence-of-dental-caries",totalDownloads:13,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Caries - The Selection of Restoration Methods and Restorative Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11565.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"82357",title:"Caries Management Aided by Fluorescence-Based Devices",doi:"10.5772/intechopen.105567",signatures:"Atena Galuscan, Daniela Jumanca and Aurora Doris Fratila",slug:"caries-management-aided-by-fluorescence-based-devices",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Caries - The Selection of Restoration Methods and Restorative Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11565.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"81894",title:"Diet and Nutrition and Their Relationship with Early Childhood Dental Caries",doi:"10.5772/intechopen.105123",signatures:"Luanna Gonçalves Ferreira, Giuliana de Campos Chaves Lamarque and Francisco Wanderley Garcia Paula-Silva",slug:"diet-and-nutrition-and-their-relationship-with-early-childhood-dental-caries",totalDownloads:20,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Caries - The Selection of Restoration Methods and Restorative Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11565.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"78064",title:"The Salivary Secretome",doi:"10.5772/intechopen.98278",signatures:"Luís Perpétuo, Rita Ferreira, Sofia Guedes, Francisco Amado and Rui Vitorino",slug:"the-salivary-secretome",totalDownloads:108,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Periodontology - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11566.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"65334",title:"Introductory Chapter: Some Important Aspects of Root Canal Treatment",doi:"10.5772/intechopen.83653",signatures:"Ana Luiza de Carvalho Felippini",slug:"introductory-chapter-some-important-aspects-of-root-canal-treatment",totalDownloads:852,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Ana Luiza",surname:"De Carvalho Felippini"}],book:{title:"Root Canal",coverURL:"https://cdn.intechopen.com/books/images_new/7133.jpg",subseries:{id:"1",title:"Oral Health"}}}]},publishedBooks:{paginationCount:4,paginationItems:[{type:"book",id:"10794",title:"Potassium in Human Health",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10794.jpg",slug:"potassium-in-human-health",publishedDate:"July 20th 2022",editedByType:"Edited by",bookSignature:"Jie Tang",hash:"0fbab5c7b5baa903a6426e7bbd9f99ab",volumeInSeries:12,fullTitle:"Potassium in Human Health",editors:[{id:"181267",title:"Dr.",name:"Jie",middleName:null,surname:"Tang",slug:"jie-tang",fullName:"Jie Tang",profilePictureURL:"https://mts.intechopen.com/storage/users/181267/images/system/181267.png",institutionString:"Brown University",institution:{name:"Brown University",institutionURL:null,country:{name:"United States of America"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10835",title:"Autonomic Nervous System",subtitle:"Special Interest Topics",coverURL:"https://cdn.intechopen.com/books/images_new/10835.jpg",slug:"autonomic-nervous-system-special-interest-topics",publishedDate:"July 20th 2022",editedByType:"Edited by",bookSignature:"Theodoros Aslanidis and Christos Nouris",hash:"48ac242dc6c5073b2590a509c44628e2",volumeInSeries:14,fullTitle:"Autonomic Nervous System - Special Interest Topics",editors:[{id:"200252",title:"Dr.",name:"Theodoros",middleName:null,surname:"Aslanidis",slug:"theodoros-aslanidis",fullName:"Theodoros Aslanidis",profilePictureURL:"https://mts.intechopen.com/storage/users/200252/images/system/200252.png",institutionString:"Saint Paul General Hospital of Thessaloniki",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8430",title:"Neurodevelopment and Neurodevelopmental Disorder",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8430.jpg",slug:"neurodevelopment-and-neurodevelopmental-disorder",publishedDate:"November 27th 2019",editedByType:"Edited by",bookSignature:"Michael Fitzgerald",hash:"696c96d038de473216e48b199613c111",volumeInSeries:6,fullTitle:"Neurodevelopment and Neurodevelopmental Disorder",editors:[{id:"205005",title:"Dr.",name:"Michael",middleName:null,surname:"Fitzgerald",slug:"michael-fitzgerald",fullName:"Michael Fitzgerald",profilePictureURL:"https://mts.intechopen.com/storage/users/205005/images/system/205005.jpg",institutionString:"Independant Researcher",institution:{name:"Trinity College Dublin",institutionURL:null,country:{name:"Ireland"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8797",title:"Adipose Tissue",subtitle:"An Update",coverURL:"https://cdn.intechopen.com/books/images_new/8797.jpg",slug:"adipose-tissue-an-update",publishedDate:"November 6th 2019",editedByType:"Edited by",bookSignature:"Leszek Szablewski",hash:"34880b7b450ef96fa5063c867c028b02",volumeInSeries:4,fullTitle:"Adipose Tissue - An Update",editors:[{id:"49739",title:"Dr.",name:"Leszek",middleName:null,surname:"Szablewski",slug:"leszek-szablewski",fullName:"Leszek Szablewski",profilePictureURL:"https://mts.intechopen.com/storage/users/49739/images/system/49739.jpg",institutionString:"Medical University of Warsaw",institution:{name:"Medical University of Warsaw",institutionURL:null,country:{name:"Poland"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.png",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}},{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}}]},submityourwork:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:11,numberOfPublishedChapters:91,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:333,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:11,numberOfPublishedChapters:144,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:126,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:23,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:13,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],subseriesList:[{id:"3",title:"Bacterial Infectious Diseases",scope:"