\\n\\n
These books synthesize perspectives of renowned scientists from the world’s most prestigious institutions - from Fukushima Renewable Energy Institute in Japan to Stanford University in the United States, including Columbia University (US), University of Sidney (AU), University of Miami (USA), Cardiff University (UK), and many others.
\\n\\nThis collaboration embodied the true essence of Open Access by simplifying the approach to OA publishing for Academic editors and authors who contributed their research and allowed the new research to be made available free and open to anyone anywhere in the world.
\\n\\nTo celebrate the 50 books published, we have gathered them at one location - just one click away, so that you can easily browse the subjects of your interest, download the content directly, share it or read online.
\\n\\n\\n\\n\\n"}]',published:!0,mainMedia:null},components:[{type:"htmlEditorComponent",content:'
IntechOpen and Knowledge Unlatched formed a partnership to support researchers working in engineering sciences by enabling an easier approach to publishing Open Access content. Using the Knowledge Unlatched crowdfunding model to raise the publishing costs through libraries around the world, Open Access Publishing Fee (OAPF) was not required from the authors.
\n\nInitially, the partnership supported engineering research, but it soon grew to include physical and life sciences, attracting more researchers to the advantages of Open Access publishing.
\n\n\n\nThese books synthesize perspectives of renowned scientists from the world’s most prestigious institutions - from Fukushima Renewable Energy Institute in Japan to Stanford University in the United States, including Columbia University (US), University of Sidney (AU), University of Miami (USA), Cardiff University (UK), and many others.
\n\nThis collaboration embodied the true essence of Open Access by simplifying the approach to OA publishing for Academic editors and authors who contributed their research and allowed the new research to be made available free and open to anyone anywhere in the world.
\n\nTo celebrate the 50 books published, we have gathered them at one location - just one click away, so that you can easily browse the subjects of your interest, download the content directly, share it or read online.
\n\n\n\n\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"3712",leadTitle:null,fullTitle:"Waste Management",title:"Waste Management",subtitle:null,reviewType:"peer-reviewed",abstract:"Solid Waste Management is one of the essential obligatory functions of the Urban Local Bodies/Municipal Corporation. 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Guzmán, Israel Salguero, Carmen Mata Martín, Elena López Acedo, Estrella Guarino, Ma Antonia Sánchez-Romero, Vic Norris and Alfonso Jiménez-Sánchez",authors:[{id:"38783",title:"Prof.",name:"Elena",middleName:"C.",surname:"Guzman",fullName:"Elena Guzman",slug:"elena-guzman"},{id:"50175",title:"Prof.",name:"Israel",middleName:null,surname:"Salguero",fullName:"Israel Salguero",slug:"israel-salguero"},{id:"50176",title:"Prof.",name:"Estrella",middleName:null,surname:"Guarino Almeida",fullName:"Estrella Guarino Almeida",slug:"estrella-guarino-almeida"},{id:"50177",title:"Prof.",name:"Elena",middleName:"López",surname:"López-Acedo",fullName:"Elena López-Acedo",slug:"elena-lopez-acedo"},{id:"50178",title:"Prof.",name:"María",middleName:"Antonia",surname:"Sánchez-Romero",fullName:"María Sánchez-Romero",slug:"maria-sanchez-romero"},{id:"50179",title:"Prof.",name:"Victor",middleName:null,surname:"Norris",fullName:"Victor Norris",slug:"victor-norris"},{id:"50180",title:"Prof.",name:"Alfonso",middleName:null,surname:"Jiménez-Sánchez",fullName:"Alfonso Jiménez-Sánchez",slug:"alfonso-jimenez-sanchez"},{id:"67145",title:"Prof.",name:"Carmen",middleName:null,surname:"Mata Martín",fullName:"Carmen Mata Martín",slug:"carmen-mata-martin"}]},{id:"16937",title:"Replication Origin Selection and Pre-Replication Complex Assembly",slug:"replication-origin-selection-and-pre-replication-complex-assembly",signatures:"Kusic-Tisma Jelena and Stefanovic Dragana",authors:[{id:"43279",title:"Dr.",name:"Jelena",middleName:null,surname:"Kusic-Tisma",fullName:"Jelena Kusic-Tisma",slug:"jelena-kusic-tisma"},{id:"49259",title:"Dr.",name:"Dragana",middleName:null,surname:"Stefanovic",fullName:"Dragana Stefanovic",slug:"dragana-stefanovic"}]},{id:"16938",title:"The Coordination between DNA Replication Initiation and Other Cell Cycle Events",slug:"the-coordination-between-dna-replication-initiation-and-other-cell-cycle-events",signatures:"Shijiao Huang and Chuanmao Zhang",authors:[{id:"44119",title:"Prof.",name:"Chuanmao",middleName:null,surname:"Zhang",fullName:"Chuanmao Zhang",slug:"chuanmao-zhang"},{id:"50637",title:"MSc.",name:"Shijiao",middleName:null,surname:"Huang",fullName:"Shijiao Huang",slug:"shijiao-huang"}]},{id:"16939",title:"The Organisation of Replisomes",slug:"the-organisation-of-replisomes",signatures:"Anna Ligasová and Karel Koberna",authors:[{id:"31390",title:"Dr.",name:"Anna",middleName:null,surname:"Ligasová",fullName:"Anna Ligasová",slug:"anna-ligasova"},{id:"31392",title:"Dr.",name:"Karel",middleName:null,surname:"Koberna",fullName:"Karel Koberna",slug:"karel-koberna"}]},{id:"16940",title:"Eukaryotic Replication Barriers: How, Why and Where Forks Stall",slug:"eukaryotic-replication-barriers-how-why-and-where-forks-stall",signatures:"Jacob Z. Dalgaard, Emma L. Godfrey and Ramsay J. MacFarlane",authors:[{id:"37092",title:"Dr.",name:"Ramsay",middleName:null,surname:"McFarlane",fullName:"Ramsay McFarlane",slug:"ramsay-mcfarlane"},{id:"38679",title:"Dr.",name:"Jacob",middleName:null,surname:"Dalgaard",fullName:"Jacob Dalgaard",slug:"jacob-dalgaard"}]},{id:"16941",title:"Control of Telomeric DNA Replication: Genetics, Molecular Biology, and Physiology",slug:"control-of-telomeric-dna-replication-genetics-molecular-biology-and-physiology",signatures:"Akira Matsuura and Aiko Matsui",authors:[{id:"31831",title:"Prof.",name:"Akira",middleName:null,surname:"Matsuura",fullName:"Akira Matsuura",slug:"akira-matsuura"},{id:"46855",title:"MSc",name:"Aiko",middleName:null,surname:"Matsui",fullName:"Aiko Matsui",slug:"aiko-matsui"}]},{id:"16942",title:"Telomere Maintenance in Organisms without Telomerase",slug:"telomere-maintenance-in-organisms-without-telomerase",signatures:"James M. Mason, Hemakumar M. Reddy and Radmila Capkova Frydrychova",authors:[{id:"34627",title:"Dr.",name:"James",middleName:null,surname:"Mason",fullName:"James Mason",slug:"james-mason"},{id:"47444",title:"Dr.",name:"Hemakumar",middleName:"M",surname:"Reddy",fullName:"Hemakumar Reddy",slug:"hemakumar-reddy"},{id:"47445",title:"Mr.",name:"Radmila",middleName:null,surname:"Capkova Frydrychova",fullName:"Radmila Capkova Frydrychova",slug:"radmila-capkova-frydrychova"}]},{id:"16943",title:"Eukaryote DNA Replication and Recombination: an Intimate Association",slug:"eukaryote-dna-replication-and-recombination-an-intimate-association",signatures:"Ramsay J. McFarlane, Khalid Al-Zeer and Jacob Z. Dalgaard",authors:[{id:"37092",title:"Dr.",name:"Ramsay",middleName:null,surname:"McFarlane",fullName:"Ramsay McFarlane",slug:"ramsay-mcfarlane"},{id:"38679",title:"Dr.",name:"Jacob",middleName:null,surname:"Dalgaard",fullName:"Jacob Dalgaard",slug:"jacob-dalgaard"},{id:"50244",title:"Mr.",name:"Khalid",middleName:null,surname:"Al-Zeer",fullName:"Khalid Al-Zeer",slug:"khalid-al-zeer"}]},{id:"16944",title:"Cell Cycle Regulation of DNA Replication in S. cerevisiae",slug:"cell-cycle-regulation-of-dna-replication-in-s-cerevisiae",signatures:"Jorrit M. Enserink",authors:[{id:"33415",title:"Dr.",name:"Jorrit M.",middleName:"M.",surname:"Enserink",fullName:"Jorrit M. Enserink",slug:"jorrit-m.-enserink"}]},{id:"16945",title:"Free Histones and the Cell Cycle",slug:"free-histones-and-the-cell-cycle",signatures:"Douglas Maya, Macarena Morillo-Huesca, Sebastián Chávez and Mari-Cruz Muñoz-Centeno",authors:[{id:"47289",title:"Dr.",name:"Mari Cruz",middleName:null,surname:"Muñoz-Centeno",fullName:"Mari Cruz Muñoz-Centeno",slug:"mari-cruz-munoz-centeno"},{id:"57750",title:"MSc.",name:"Douglas",middleName:null,surname:"Maya",fullName:"Douglas Maya",slug:"douglas-maya"},{id:"57751",title:"Dr.",name:"Macarena",middleName:null,surname:"Morillo-Huesca",fullName:"Macarena Morillo-Huesca",slug:"macarena-morillo-huesca"},{id:"57752",title:"Prof.",name:"Sebastian",middleName:null,surname:"Chavez",fullName:"Sebastian Chavez",slug:"sebastian-chavez"}]},{id:"16946",title:"Involvement of Linker Histones in the Regulation of Replication Timing",slug:"nvolvement-of-linker-histones-in-the-regulation-of-replication-timing",signatures:"Christophe Thiriet, Gwenola Auda-Boucher and Yvonnick Chéraud",authors:[{id:"35593",title:"Dr.",name:"Christophe",middleName:null,surname:"Thiriet",fullName:"Christophe Thiriet",slug:"christophe-thiriet"},{id:"62335",title:"Dr.",name:"Gwenola",middleName:null,surname:"Auda-Boucher",fullName:"Gwenola Auda-Boucher",slug:"gwenola-auda-boucher"},{id:"62336",title:"Dr.",name:"Yvonnick",middleName:null,surname:"Chéraud",fullName:"Yvonnick Chéraud",slug:"yvonnick-cheraud"}]},{id:"16947",title:"Replication Timing: Evolution, Nuclear Organization and Relevance for Human Disease",slug:"replication-timing-evolution-nuclear-organization-and-relevance-for-human-disease",signatures:"Megan Lynne Wright and Frank Grützner",authors:[{id:"50470",title:"Dr.",name:"Frank",middleName:null,surname:"Grutzner",fullName:"Frank Grutzner",slug:"frank-grutzner"},{id:"51395",title:"BSc",name:"Megan Lynne",middleName:"Lynne",surname:"Wright",fullName:"Megan Lynne Wright",slug:"megan-lynne-wright"}]},{id:"16948",title:"The Silencing Face of DNA Replication: Gene Repression Mediated by DNA Replication Factors",slug:"the-silencing-face-of-dna-replication-gene-repression-mediated-by-dna-replication-factors",signatures:"Patricia Chisamore-Robert, Daniel Jeffery and Krassimir Yankulov",authors:[{id:"35323",title:"Prof.",name:"Krassimir",middleName:null,surname:"Yankulov",fullName:"Krassimir Yankulov",slug:"krassimir-yankulov"},{id:"49645",title:"Mr.",name:"Daniel",middleName:"Charles Barrie",surname:"Jeffery",fullName:"Daniel Jeffery",slug:"daniel-jeffery"},{id:"49646",title:"Ms.",name:"Patricia",middleName:null,surname:"Chisamore-Robert",fullName:"Patricia Chisamore-Robert",slug:"patricia-chisamore-robert"}]},{id:"16949",title:"Faithful DNA Replication Requires Regulation of CDK Activity by Checkpoint Kinases",slug:"faithful-dna-replication-requires-regulation-of-cdk-activity-by-checkpoint-kinases",signatures:"Claus Storgaard Sørensen, Halfdan Beck, Viola Nähse-Kumpf and Randi G. Syljuåsen",authors:[{id:"32018",title:"Dr.",name:"Claus",middleName:null,surname:"Sørensen",fullName:"Claus Sørensen",slug:"claus-sorensen"},{id:"51208",title:"Mr.",name:"Halfdan",middleName:null,surname:"Beck",fullName:"Halfdan Beck",slug:"halfdan-beck"},{id:"51209",title:"Prof.",name:"Randi",middleName:"Gussgard",surname:"Syljuåsen",fullName:"Randi Syljuåsen",slug:"randi-syljuasen"},{id:"103105",title:"Mrs.",name:"Viola",middleName:null,surname:"Nähse-Kumpf",fullName:"Viola Nähse-Kumpf",slug:"viola-nahse-kumpf"}]},{id:"16950",title:"Regulation of the G1/S Transition in Adult Liver: Expression and Activation of the Cyclin Dependent Kinase Cdk1 in Differentiated Hepatocytes is Controlled by Extracellular Signals and is Crucial for Commitment to DNA Replication",slug:"regulation-of-the-g1-s-transition-in-adult-liver-expression-and-activation-of-the-cyclin-dependent-k",signatures:"Loyer Pascal and Corlu Anne",authors:[{id:"35638",title:"Mrs.",name:"Anne",middleName:null,surname:"Corlu",fullName:"Anne Corlu",slug:"anne-corlu"},{id:"49777",title:"Mr.",name:"Pascal",middleName:null,surname:"Loyer",fullName:"Pascal Loyer",slug:"pascal-loyer"}]},{id:"16951",title:"Binding of Human MCM-BP with MCM2-7 Proteins",slug:"binding-of-human-mcm-bp-with-mcm2-7-proteins",signatures:"Ryoko Kon, Shunsuke Kusunoki, Naohito Nozaki and Yukio Ishimi",authors:[{id:"35711",title:"Prof.",name:"Yukio",middleName:null,surname:"Ishimi",fullName:"Yukio Ishimi",slug:"yukio-ishimi"},{id:"48693",title:"Ms.",name:"Ryoko",middleName:null,surname:"Kon",fullName:"Ryoko Kon",slug:"ryoko-kon"},{id:"48695",title:"Mr.",name:"Shunsuke",middleName:null,surname:"Kusunoki",fullName:"Shunsuke Kusunoki",slug:"shunsuke-kusunoki"},{id:"48696",title:"Dr.",name:"Naohito",middleName:null,surname:"Nozaki",fullName:"Naohito Nozaki",slug:"naohito-nozaki"}]},{id:"16952",title:"DNA Replication in Animal Systems Lacking Thioredoxin Reductase I",slug:"dna-replication-in-animal-systems-lacking-thioredoxin-reductase-i",signatures:"Edward E. Schmidt",authors:[{id:"46747",title:"Prof.",name:"Edward",middleName:null,surname:"Schmidt",fullName:"Edward Schmidt",slug:"edward-schmidt"}]},{id:"16953",title:"Prevalence of Reactivation of Hepatitis B Virus DNA Replication in Rheumatoid Arthritis Patients",slug:"prevalence-of-reactivation-of-hepatitis-b-virus-dna-replication-in-rheumatoid-arthritis-patients",signatures:"Yukitomo Urata, Ryoko Uesato and Dai Tanaka",authors:[{id:"41260",title:"Dr.",name:"Yukitomo",middleName:null,surname:"Urata",fullName:"Yukitomo Urata",slug:"yukitomo-urata"},{id:"50634",title:"Dr.",name:"Ryoko",middleName:null,surname:"Uesato",fullName:"Ryoko Uesato",slug:"ryoko-uesato"},{id:"50635",title:"Dr.",name:"Dai",middleName:null,surname:"Tanaka",fullName:"Dai Tanaka",slug:"dai-tanaka"}]},{id:"16954",title:"Oncogenic Aspects of HPV Infections of the Female Genital Tract",slug:"oncogenic-aspects-of-hpv-infections-of-the-female-genital-tract",signatures:"Josko Zekan, Maja Sirotkovic-Skerlev and Mihael Skerlev",authors:[{id:"33907",title:"Dr.",name:"Josko",middleName:null,surname:"Zekan",fullName:"Josko Zekan",slug:"josko-zekan"},{id:"48890",title:"Prof.",name:"Maja",middleName:null,surname:"Sirotkovic-Skerlev",fullName:"Maja Sirotkovic-Skerlev",slug:"maja-sirotkovic-skerlev"},{id:"48891",title:"Prof.",name:"Mihael",middleName:null,surname:"Skerlev",fullName:"Mihael Skerlev",slug:"mihael-skerlev"}]},{id:"16955",title:"The Role of E2 Proteins in Papillomavirus DNA Replication",slug:"the-role-of-e2-proteins-in-papillomavirus-dna-replication",signatures:"Reet Kurg",authors:[{id:"35560",title:"Dr.",name:"Reet",middleName:null,surname:"Kurg",fullName:"Reet Kurg",slug:"reet-kurg"}]},{id:"16956",title:"Topoisomerase I and II Expression in Recurrent Colorectal Cancer Cells: A Dubious Matter",slug:"topoisomerase-i-and-ii-expression-in-recurrent-colorectal-cancer-cells-a-dubious-matter",signatures:"Panagiotis Gouveris, Elias Skopelitis and Nicolas Tsavaris",authors:[{id:"43625",title:"Prof.",name:"Nicolas",middleName:null,surname:"Tsavaris",fullName:"Nicolas Tsavaris",slug:"nicolas-tsavaris"},{id:"50393",title:"Dr.",name:"Panagiotis",middleName:null,surname:"Gouveris",fullName:"Panagiotis Gouveris",slug:"panagiotis-gouveris"},{id:"50394",title:"Dr.",name:"Elias",middleName:null,surname:"Skopelitis",fullName:"Elias Skopelitis",slug:"elias-skopelitis"}]},{id:"16957",title:"Bacterial Genetics of Large Mammalian DNA Viruses: Bacterial Artificial Chromosomes as a Prerequisite for Efficiently Studying Viral DNA Replication and Functions",slug:"bacterial-genetics-of-large-mammalian-dna-viruses-bacterial-artificial-chromosomes-as-a-prerequisite",signatures:"Felix Wussow, Tanja Spieckermann, Anne Brunnemann, Linda Hüske, Tuna Toptan and Helmut Fickenscher",authors:[{id:"31956",title:"Prof.",name:"Helmut",middleName:null,surname:"Fickenscher",fullName:"Helmut Fickenscher",slug:"helmut-fickenscher"},{id:"50263",title:"MSc.",name:"Anne",middleName:null,surname:"Brunnemann",fullName:"Anne Brunnemann",slug:"anne-brunnemann"},{id:"50264",title:"MSc.",name:"Linda",middleName:null,surname:"Hueske",fullName:"Linda Hueske",slug:"linda-hueske"},{id:"50265",title:"MSc.",name:"Tanja",middleName:null,surname:"Spieckermann",fullName:"Tanja Spieckermann",slug:"tanja-spieckermann"},{id:"50266",title:"Dr.",name:"Tuna",middleName:null,surname:"Toptan",fullName:"Tuna Toptan",slug:"tuna-toptan"},{id:"50267",title:"Dr.",name:"Felix",middleName:null,surname:"Wussow",fullName:"Felix Wussow",slug:"felix-wussow"}]}]}],publishedBooks:[{type:"book",id:"1907",title:"Reviews on Selected Topics of Telomere Biology",subtitle:null,isOpenForSubmission:!1,hash:"5f4f25ba706645403bab2aa721a0809b",slug:"reviews-on-selected-topics-of-telomere-biology",bookSignature:"Bibo Li",coverURL:"https://cdn.intechopen.com/books/images_new/1907.jpg",editedByType:"Edited by",editors:[{id:"109879",title:"Dr.",name:"Bibo",surname:"Li",slug:"bibo-li",fullName:"Bibo Li"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1967",title:"Molecular Interactions",subtitle:null,isOpenForSubmission:!1,hash:"522b62bf32423a57eeceb0bf150e5a66",slug:"molecular-interactions",bookSignature:"Aurelia Meghea",coverURL:"https://cdn.intechopen.com/books/images_new/1967.jpg",editedByType:"Edited by",editors:[{id:"104880",title:"Prof.",name:"Aurelia",surname:"Meghea",slug:"aurelia-meghea",fullName:"Aurelia Meghea"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2569",title:"Protein Phosphorylation in Human Health",subtitle:null,isOpenForSubmission:!1,hash:"8c0b00cb583f566e77b3e553b1aa5920",slug:"protein-phosphorylation-in-human-health",bookSignature:"Cai 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It is opinion dynamics that simulate what kind of opinion distribution it will form. Ideally, people in a society should be bound together by trust. However, in reality, people often distrust each other and rebel against each other. In this chapter, we will apply opinion dynamics to take into account the distrust between such people and describe how trust and distrust affect the composition of society.
Opinion dynamics is a field that has been studied for a long time with applications to consensus building and elections in society [1, 2]. The transition of social discussions leading to consensus building is an old problem, but it is also an important theme in the analysis of various communications on the Internet in modern society. The opinion dynamics of binary opinions (agree and disagree or agree and ignore) have long been studied in analogy with magnetic physics [3, 4, 5, 6, 7, 8, 9]. In addition, since 2000, the Bounded Confidence Model, which analyzes opinions not as binary values but as continuously varying quantities, has been presented, and more precise studies have been conducted [10, 11, 12, 13, 14].
However, the conventional Bounded Confidence Model implicitly assumes social consensus. In Gérard Weisbuch et al. [10] and Hegselmann-Krause [11], which are representative theories of the Bounded Confidence Model, the opinions of individual people are expressed as Ii(t) in the following equation. Here, the coefficient Dij, which indicates the degree of influence by other people’s opinions, is limited to positive values.
In the Bounded Confidence Model, the coefficient is considered to be a factor that represents the speed of convergence of opinions. If the coefficient is limited to a positive value, the opinions of everyone converge without fail, and the larger the positive value, the faster the convergence. In other words, it is not the results of individual simulations that cause the convergence of social opinions, but rather the Bounded Confidence Model [10, 11, 12, 13, 14] itself, in which the convergence of social opinions is inherent from the beginning.
The reality of opinions in society is that not all opinions can be agreed upon. In social issues, it is rather rare to reach a consensus. In reality, we all experience cases where we feel opposition to someone’s opinion. Therefore, Ishii and Kawahata extended the Bounded Confidence Model by introducing repulsion and distrust of opinions [15, 16, 17, 18, 19, 20]. Simply put, the extension is that the coefficients are not limited to positive values, but negative values are introduced, and positive values indicate a trust relationship, while negative values indicate a distrust relationship. If the coefficient is negative, the opinions will be separated from each other every moment. In other words, they will never reach a consensus. This new theory of opinion dynamics is called the Trust-Distrust Model.
Using this theory of opinion dynamics, calculations have been made for the case of a person who is charismatically popular in society [20] and for the case of a person who is disliked by society as a whole [18], and calculations can also be made for the case of a society splitting, so this theory of opinion dynamics has the potential to enable social simulation calculations for many social movements.
In addition, the theory of opinion dynamics with multiple axes of opinion has been proposed by Ishii and Okano, and analysis has been conducted with two axes of opinion, so-called “official stance” and “real opinion” [21].
Even between individuals with limited time and space, active exchange of opinions has become possible [22]. In recent years, there are more and more cases in which the prerequisite information for conventional communication (e.g., the other person’s gender, appearance, tone of voice) cannot be established without exchanging personal information. In recent years, however, immediate two-way communication with excerpts of personal information such as letters and pictograms has become the norm. However, there are advantages and disadvantages to using information assets in the form of personalized data, which are excerpts of personal information as described above. The above discussion has already started in the 1950s when the use of the Internet was limited in the U.S. and the former Soviet Union; in the early 1990s, the Internet became available to the general public and the discussion was accelerated based on the concept of the information highway. Today, the status of information asset management and personalized data management differs from country to country. This has led to various problems in terms of economic loss and education related to the development of human resources involved in the proper management of information assets using data (e.g., data scientist training, legal development, moral and ethical education in handling data). In Japan, on the other hand, with the spread of mobile communications, the flat-rate system for telecommunications was applied early and actively operated at a rapid pace from the late 1990s to the early 2000s. In particular, the flat-rate system was introduced at a lower cost than in neighboring Asian countries, and advanced efforts were made in terms of information transmission. However, against the backdrop of this rapid progress, it is difficult to say that awareness-raising and legislation regarding the use of the Internet among the compulsory education generation and the generation that is not familiar with Internet literacy and cyber security (assumed to be socially vulnerable groups such as children and the elderly) has progressed. It is possible that communication is repeatedly evolving. In recent years, there have been cases of fake news being disseminated on a large scale. As a result, there have been cases where misconceptions about personal information have spread. In some cases, this may even occur in the community, resulting in a “big wave of information” on an individual basis. While we cannot be certain that there are adequate warnings and laws regarding how to use the Internet, communication may continue to evolve. Therefore, social networking services are always at risk of becoming hotbeds of conflicts and criminal activities that sometimes spill over into society as a whole, and risk management for them has been actively discussed in recent years. In particular, the COVID-19 disaster has increased the need for risk management due to the increased use of online communication. This issue raises concerns not only about the parties involved, but also about the responsibility of those who accidentally spread fake news that pose a great risk to the lives of both parties. How to deal with such cases will need to be discussed in the future. On the other hand, there are concerns about the emergence of a new “digital divide”. In the past, the divide over the superiority of handling computer technology itself was a hot topic in Japan from 2004 to 2005. However, the new “digital divide” assumes that computer technology is available to some extent regardless of gender or age. The differences are differences in literacy due to differences in the ability to transmit information (such as loudness of voice) and extract information. It can be assumed that there will be cases of false understanding, such as being evaluated by the number of people on the web. In this regard, since the beginning of this year, social networking sites have taken measures such as speech control and account restrictions to ensure fairness in elections (e.g. in the US and English-speaking countries). However, in order to ensure fairness, there is a limit to large-scale policing through mechanical processes in the Japanese sphere, which has a complex linguistic context including English, katakana, hiragana, and kanji. Therefore, it can be said that education also requires reading comprehension in all kinds of texts and a perspective on preserving the information resources of individuals. In this regard, those who are vulnerable in the information environment, such as the generation that has not been adequately educated on cyber security, may be at risk of various fragmentation. As a result of this information gap, a threshold of distrust and trust in communication occurs, and sometimes there are scattered cases of major mistakes such as major social fragmentation, deadly attacks, and slander against completely disinterested entities. In the case of socially vulnerable people, there is a limit to the legal measures that can be taken without financial benefits such as hiring a lawyer, and there is a risk that socially vulnerable people who should be protected will be left defenseless or denounced. To remedy them, social protection and remedy mechanisms in online communities, such as digital citizenship, are also urgently needed, and even within those communities, consensus building, trust building, and to some extent, thresholds occur. In addition, slander and defamation may be committed without the person being aware of it and he or she may be held responsible for it. Only those who are in a superior position to apply the law are protected and enjoy many benefits, while those who are not in a position to denounce based on legal grounds may cry themselves to sleep or suffer losses without any social guarantee. In such cases, although there are problems such as surveillance society, digital citizenship, and other network communication in neighborly relations, the formation of communities that protect each other regardless of social class is more important. And there are expected to work as part of care work in online communities. In these elements, it can be said that mutual care communication based on mutual “trust“ and very close relationships, neighborly relationships, is promoted. It can be hypothesized that these online pseudo-societies, which promote the building of invisible trust relationships formed between distant and nearby communities, have something in common with the wider society. Since the rapid spread of public networks, there have been growing expectations for elucidating the mechanisms of social phenomena that have become difficult to visualize and quantify [23]. However, in order to analyze the exchange of opinions left in the vast amount of log data in modern society, it goes without saying that a theory that corresponds to quantitative analysis, focusing on integration with analysis to large-scale data, is necessary. In addition, slander and defamation may be committed without the person being aware of it and he or she may be held responsible for it. Only those who are in a superior position to apply the law are protected and enjoy many benefits, while those who are in a position not to be denounced on legal grounds may cry themselves to sleep or suffer losses, without any social guarantee. Similar functions are ensured in functions such as suggestions in online search behavior and product recommendations in e-commerce, etc. In addition, opinions that infer our trust or distrust, which constitute the recommendation function, become “opinion aggregates” or “generalization models” that are automatically returned to us through public networks. These are the results of online consensus building; in COVID-19, generalized models and recommendations for various social crisis situations will be developed and analyzed based on large-scale data such as our behavior logs and opinions. However, the global spread of public networks has not been positive in all aspects, and while COVID-19 has increased excessively, problems such as online slander have also been highlighted. This chapter touches on those issues as well. In particular, a case can be envisioned where public opinion is formed from the aftermath of unconscious consensus building. This is the case today, when populism and propaganda are rampant. However, the use of online media was pioneered in the 2020 U.S. presidential election, and typical social networking sites such as Facebook and Twitter have been suppressed, and regulations and laws are being revised at a rapid pace. From this point of view, it can be inferred that the nature of online communication is entering a transitional period after COVID-19 and the 2020 U.S. presidential election. It is now possible to pseudo-analyze various opinions in society through online logs. Theories for analyzing the process of consensus building in society (or small groups) have long been proposed and studied from various perspectives [10, 11, 12, 13, 14]. However, in order to analyze the exchange of opinions left in the vast amount of log data of modern society, it goes without saying that a theory that corresponds to quantitative analysis, focusing on integration with analysis to large-scale data, is necessary. There are two main types of theories of opinion dynamics. One is the theory that treats contradictory conditions and discrete opinions as 1 (trust) and 0 (distrust), or 1 (trust) and -1 (distrust). In presidential elections in the U.S. and France, and in referendums such as those seen in Brexit, this dichotomous theory is more likely to be applied because voting takes place when there is one clear winner. The other method is the theory that regards opinions as a continuous value with one (or many) dimensions. For example, consensus building is often considered in this way [15, 16, 17, 18, 19, 20]. As for the discussion of public health risk management in the COVID-19 disaster, which is imminent every day as described above, the number of articles being updated and recorrected is increasing every day. Changes in information on the web provide a bird’s eye view of the situation, which is often different from the expected case. In addition, there is an urgent need to “democratize security” in order to appeal to, resolve, and protect vulnerable members of society who do not fully understand cyber security. Depending on future legal decisions, significant changes may occur. In addition, there is a need to share security awareness in cyberspace as well as offline crime arrest rates in society. In addition, in various online communities, organizations may be formed to protect each other’s security in the form of blockchain, just like the “Ren” (ex. creation critics’ community) formed in the Edo period in Japan. In the aforementioned communities, there is a communication and consensus that can only be established if there is a clear relationship of trust and distrust. In recent years, while consensus-based communication has increased, disparities and security issues have also been detected, and more and more fatal flaws and security errors in online communities have been uncovered that were not previously apparent. The mechanism by which these problems are discovered can occur when there is a sense of distrust among a certain number of people in a community. In the context of information and communication known as “technological warfare” or “quiet information warfare,” the threshold values of parameters related to the sense of trust and distrust among communities are important information for communication to take place, but they are difficult to determine, quantify, and visualize clearly. Therefore, it is necessary to reason based on mathematical models, develop arguments and predictions, and confront possible risks and potential social problems. These issues, as well as election prediction, are themes that involve implicit understandings, such as floating and fixed votes, and consensus among regions, so we try to consider them together with social discussions in consensus building [15, 16, 17, 18, 19, 20, 21].
In the opinion dynamics proposed by Ishii named Trust-Distrust Model, the time evolution of people’s opinions in the society is expressed by the following Equation [16].
The first term on the right-hand side is the influence of external media such as advertising, mass media reports, and government publicity, where A(t) is the influence from mass media from time to time, and the coefficient ci is the coefficient of how much influence each person receives from that mass media. The coefficient Dij can be negative [15, 16]. Here, the function f(Ii,Ij) is a cutoff function that is ignored when the opinions are farther apart than a certain degree. Hegselmann-Krause [11] uses a simple step function, but here we use the Sigmoid function in the sense of a smooth cutoff.
Here, the coefficients of trust and distrust, Dij and Dji, are considered to be independent. Usually, Dij is an asymmetric matrix with Dij ̸= Dji. Moreover, Dijand Dji can take positive and negative values with different signs. A positive value means that i trusts j, while a negative value means that i does not trust j. Also, m is the strength of will of agent “i”. For large values of m, the agent “i” is not so much influenced by mass media or other people’s opinions.
The Trust-Distrust Model can be used to calculate the case of a person who is charismatically popular in society [22] and the case of a person who is disliked by society as a whole [18], and it can also be used to calculate the case of a society splitting up [23, 24, 25], so the Trust-Distrust Model has the potential to provide social simulation calculations for many social movements.
Here is a simple calculation using Trust-Distrust Model. Figure 1 shows the opinion dynamics for the case of two people, where the left side of Figure 1 shows the case where the two people trust each other (DAB > 0, DBA > 0). The right panel of Figure 1 shows the case where two people in the calculation are shown as “A” and “B”. distrust each other (DAB < 0, DBA < 0). The case of mutual trust can be found in Hegselmann-Krause [11], but the case of distrust cannot be calculated without this theory.
Example of trust-distrust model calculation using
In this Trust-Distrust Model, the influence of the mass media is expressed by the first term on the right side of Eq. (2) called ciA(t). Here, A(t) is the amount of mass media coverage of the focal topic. The quantity is simply the product of the number of seconds and the number of channels that handle the topic, and the coefficient ci on this means that we can handle the fact that each person is affected differently by this mass media.
Based on Eq. (2), the individual opinions of the people, Ii(t), are calculated over time. We assume that opinions can take values from -∞ to +∞; Hegselmann-Krause [11] has 0 to 1, but Trust-Distrust Model has no upper bound on extreme opinions (and no lower bound if negative). In this case, the initial opinions of people are distributed as uniform random numbers in the range of −20 to +20.
What is important in Trust-Distrust Model is the coefficient Dij represented in Eq. (2). In a complete network where all people are connected to all people, there are N2 coefficients Dij that express trust or distrust between individual people. Ishii and Kawahata have shown that if more than 55% of the N2 Dij are positive, that is, trustworthy, the system will form a consensus [17]. This result is also true for random networks [26].
When people in a society are bound together by trust, they reach a consensus. This is the implicit assumption and conclusion of the bounded confidence model. The time required to reach consensus and whether one or more opinions are reached can be analyzed from the calculations of the bounded confidence model.
However, if people in the society as a whole are not necessarily bound by trust, it becomes uncertain whether they will reach a consensus or not. If all the people in a society distrust each other, it is obvious that they will not reach a consensus. Then, there is an interesting question that can be confirmed by a mathematical model: what is the ratio of trust and distrust that will lead to consensus formation?
First, we use the Trust-Distrust Model to calculate whether the entire society, assuming 300 people, will form a consensus in a situation where people’s connections are mixed with trust and mistrust. Assume that these 300 people are connected by a complete network. Suppose that the coefficient of trust Dij connecting people occurs in a specified proportion of cases where the coefficient is a positive value determined by a random number between 0 and 1 and a negative value determined by a random number between −1 and 0. Let T be the proportion of positive or negative values of the trust coefficient Dij. If T = 1, the every trust coefficient Dij is positive. For example, if T = 0.5, then the positive and negative values are 50–50.
The results of the calculations are shown in Figure 2 and Figure 3 [19]. Figure 2 plots the highest value of the opinion distribution for calculations from T = 0.45 to T = 1. Since the calculations are for 300 people, the vertical axis of Figure 2 is 300 if consensus is achieved. The highest value of the distribution is over 200, indicating that the situation is close to consensus formation. On the other hand, at T = 0.45, the highest value of the opinion distribution is less than 20, suggesting that the opinion distribution does not have a sharp peak. Therefore, at T = 0.45, the situation is far from consensus building.
Variation of the highest value of the opinion distribution with the proportion T of positive and negative values of the coefficient of confidence Dij.
The changes in the opinion distribution due to the ratio of positive and negative values of the coefficient of confidence Dij, T, are calculated for T = 0.5, 0.52, 0.53, 0.54, 0.55, 0.56, 0.57, and 0.60. N = 1000 in this calculation. The probability of people connecting in a random network is set to 30%.
The above results were calculated for a complete network of 300 people. Since a complete network cannot be realized in society, calculations for the case where people are connected in a different network structure are also presented. The calculations were done for random networks and scale-free networks.
This can be seen in Figure 3, which shows the computation of the opinion distributions for T = 0.5, 0.52, 0.53, 0.54, 0.55, 0.56, 0.57, and 0.60. Let us assume that the entire society has 1000 people and is connected by a random network. The probability of people being connected is set to be 30%. As can be seen here, when T = 0.55 or higher, the opinion distribution has a sharp peak, indicating that a consensus has been formed. However, at T = 0.54, there is a peak, but it is not sharp, and at T = 0.53 or lower, the distribution of opinions is flattening out, clearly indicating that consensus has not been formed. The calculation for 300 people in the complete network is very similar to this calculation.
It is noteworthy that the highest value of the opinion distribution in Figure 2 changes rapidly with the change of T. The peak of the opinion distribution appears after T = 0.5, and the height of the peak becomes higher after T = 0.55. In other words, the value of T determines whether a society is consensus-building or not. We can see that the borderline between the two is approximately T = 0.55.
The abrupt change in the highest value of the opinion distribution seen in Figure 2 suggests that there is a borderline at around T = 0.55 where society may or may not reach a consensus. In other words, if more than 55% of the relationships in the entire social network are trust relationships, consensus building is achieved in the entire society. This means that it is not necessary for all relationships to be trusting in order for the entire society to reach consensus, but if more than 55% of the relationships are trusting, the society will reach consensus.
This conclusion suggests that in a democracy, for example, if more than 55% of the people support a certain policy in an election, it is possible for society to reach a consensus. It also suggests that it is difficult to reach a consensus when there is a strong opposition between those in favor and those against, such as when the number of those in favor is less than 55%. Thus, this conclusion is interesting as an application to political science.
The conclusion that 55% is the borderline of social consensus is very striking. However, I wonder if this conclusion is the same no matter what network structure people are connected to. Figure 4 below shows a calculation for a random network of 1000 people, where the probability of joining the random network is assumed to be 1%.
The changes in the opinion distribution due to the ratio of positive and negative values of the coefficient of confidence Dij, T, are calculated for T = 0.8, 0.75, 0.72, 0.70, 0.65, and 0.60. N = 1000 in this calculation. The probability of people connecting in a random network is set to 1%.
Figure 4 shows that the sharp peak of the opinion distribution disappears completely at T = 0.6, and the sharp peak representing consensus emerges at about T = 0.75. In other words, if people’s connections are sparse, such as the probability of joining in a random network is 1%, 55% is not the boundary of consensus formation.
For this quantitative check, we calculate the following quantity. This is the sum of the differences in the opinions of N people.
This W is W = 1 if the width of the opinion distribution remains the same over time, W < 1 if consensus is reached, and W > 1 if the opinion distribution is divergent without consensus.
Let us examine quantitatively the finding from previous researches [26, 27] that consensus is formed when positive trust between people in a society is at least 55% of all relationships. In Figure 5, we show the T dependence of W for various values of trustΔ. Dij is between -Δ to Δ. The calculation of Figure 5 is N = 1600, the connection rate of the random network is 30%. Since there are fluctuations due to random numbers, the calculated values are averaged over five times. The green horizontal line represents W = 1. In other words, if the calculation is below this green line, the society forms a consensus.
The calculated W as a function of T, the proportion of positive values of the trust coefficient Dij. N = 1600. Δ = 1.0. The average value of 10 calculations is used. The proportion 0.01, 0.05, 0.1, 0.5 and 1 is shown.
Figure 5 shows that the condition for consensus is satisfied at about T = 0.53–0.55, regardless of the size of Dij. In particular, when Δ = 1.0, we can see that when T is close to 0.55, there is a sharp inclination toward consensus. Therefore, the 55% consensus threshold from previous studies is supported. However, the threshold for consensus depends very much on the connection rate of the network: in the calculation for N = 1600, if Δ is 1.0, then W = 1 is T = 0.545 when the connection probability of the random network is 30%, but T = 0.69 when the connection probability is 1%. This means that if the network is sparsely connected, the threshold value of T will rapidly increase. In other words, if the network is sparsely connected, it will be difficult for society to reach a consensus.
In our previous work [27], we have performed the same type of calculations on scale-free networks, which are said to be closer to real human connections in society than random networks. However, in the case of scale-free networks, a clear consensus threshold such as 55% does not emerge.
People in society are not uniform, but each individual is unique. A person who is especially popular among many people is called a charismatic person. In this section, we will use the Trust-Distrust Model to simulate the case of a charismatic person who is trusted by many people.
Here, a charismatic person is one who is popular with many people in society. Although being popular among others is not synonymous with being trusted by others, in this Trust-Distrust Model, a charismatic person is considered to be a positive value with a high coefficient of trust Dij from others to the charismatic person. Thus, a charismatic person is defined as follows. The coefficient of trust, Dij, is the strength with which person “i” is influenced by a person “j”. Therefore, if the charismatic person is represented by “c” and Dic is the trust from person “i” to the charismatic person. Dic is larger than the influence from other people, then the charismatic person will have more influence.
Figure 6 shows the case where there is one charismatic person in a society of 300 people. It can be seen that many people have their opinions close to those of charismatic person. Thus, a charismatic person will be able to attract people with similar opinions. The more positive and larger the value of Dic, the stronger the effect. This is called being popular in society.
Simulation of a single charismatic person. The charismatic person is trusted by the people in the society with a trust coefficient Dic = 10, and the trust coefficients between other people in the society are determined by random numbers in the range of +1 to −1. The arrows show the opinion distribution of the charismatic person. The blue line in the opinion trajectory represents the opinion of a charismatic person, while the green line is a sample of the opinion trajectory of an ordinary person.
Figure 7 shows the case where there are two charismatic people in the society. These two people are popular and have many people who agree with their opinions. If the two charismatic people are far apart in their opinions, a middle opinion group will be formed between their opinions, but if their opinions are close, there will be no middle ground and the society will be divided between them.
Simulation of two charismatic persons. The charismatic persons are trusted by the people in the society with a trust coefficient Dic = 10. The blue line and red line in the opinion trajectory represent the opinions of a charismatic person, while the green line is a sample of the opinion trajectory of an ordinary person.
Another feature that distinguishes the Trust-Distrust Model from the traditional bounded confidence model is that it can calculate the effect of advertising on the formation of social opinion. In this section, we will consider the impact of advertising on people’s opinions of society. In general, advertising is the use of mass media to convey people’s messages [28]. Here, we do not touch on the specific method of advertising or the content of advertising but set the impact of advertising per unit time on people as A(t). A(t) can be thought of as the amount of advertising per day, e.g., the amount of money spent on advertising.
The first term on the right-hand side of Eq. (2) is A(t), where A(t) represents the strength of advertising added to society from time to time. This term of the impact of advertising is adopted with reference to the term introduced in the mathematical model of hit phenomena [29, 30], which analyzes the impact of advertising on society.
In this section, the opinions people have are expressed as one-dimensional numerical values. Therefore, an opinion with a positive value simply means that it is expressed as a positive numerical value, not that it is an affirmative opinion. The situation is the same for opinions with a negative value. Therefore, whether an opinion is positive or negative only implies the direction of the opinion on a particular topic. Whether an opinion is positive or negative does not mean that it supports or does not support a particular topic. For example, on the topic of cola, it is possible to assign a positive value to an opinion that likes Coca-Cola and a negative value to an opinion that likes Pepsi-Cola. Conversely, it is also possible to make the opinion that you like Pepsi-Cola a positive opinion and the opinion that you like Coca-Cola a negative opinion.
Figure 8 shows the effect of advertising on the distribution of opinions. From left to right, the strength of advertising is A(t) = 0, 0.5, and 5.0. When A(t) = 5.0 on the right, social opinion distribution moves significantly in the positive direction. In other words, using Eq. (2), we can include the influence of advertising in our calculations.
It shows the effect of advertising on the distribution of opinions. From left to right, a(t) = 0, 0.5, 5.0. When a(t) = 5.0 on the right, social opinion moves significantly in the positive direction.
If we define the advertising term A(t) as follows, we can concentrate the opinions of the people in the society into an arbitrary opinion.
Here, a represents how narrowly the opinion distribution should be concentrated, and b specifies where the opinion distribution should be concentrated. By setting these a and b, we can decide which and how much of society’s opinions should be concentrated. An example of this is shown in Figure 9. However, what kind of advertising can have this kind of effect is still another question.
Calculation of the concentration of the distribution of opinions in society under the influence of advertising, using
An example of this extreme simulation is shown in Figure 10. Here, the opinion of the whole society is negative at first, but due to the influence of strong advertising, the opinion of all people in the society changes to a positive value. We do not know what kind of advertising can actually have this kind of effect on society, but we have shown that it is possible in principle as a mathematical model.
Calculation of the concentration of the distribution of opinions in society under the influence of advertising, using
In the first term on the right-hand side of Eq. (2) of the Trust-Distrust Model, which represents the influence of advertising, the influence of advertising can be added separately to each person in society by setting the coefficient ci. This shows that it is possible to calculate micro-targeting, which is known in the field of marketing.
Eq. (2) also shows that people are influenced both by advertising from the mass media and by the people they are connected to in society. Today, with the development of social media, some people are not exposed to information from mass media such as television. Therefore, we will use the Trust-Distrust Model to investigate whether people who are not exposed to information from the mass media are indirectly influenced by the mass media through the influence of people who are connected to them in society [31].
In Figure 11, we set the number of people in society as a whole at 1000, of which 100 people, or 10%, are not affected by mass media. The connections between people are random networks, and the calculations for the percentage of connections are shown as 30%, 10%, 5%, and 0.5%. In Figure 12, the trajectory of the opinions of those who are influenced by the mass media is depicted in pink, and the trajectory of the opinions of those who are not influenced by the mass media is depicted in blue.
Simulation of the movement of people who are not reached by the influence of mass media. Suppose the number of people in the society is 1000, and 100 people are not reached by the influence of mass media. Calculations are shown for random networks with connection probabilities of 30%, 10%, 5%, and 0.5%. The trajectory of the opinions of those who are influenced by the mass media is pink, and the trajectory of the opinions of those who are not reached by the mass media is blue. The coefficient of people’s trust is set at a uniform random number in the range of 1 to −1, and the proportion of positive values is T = 0.6. The proportion of positive values is T = 0.6. The strength of advertising is a = 5.
Polarization of the distribution of opinions in society. (a) Polarization of opinions obtained by the bounded confidence model. The coefficient of trust Dij > 0 for everyone in the pink locus of opinion. (b) Polarization of opinion obtained with the trust-distrust model. The red and blue groups in the locus of opinion are consensus with Dij > 0 within the group and distrust with Dij < 0 between the groups.
The calculation results show that when people’s connections are sparse, some of the people who have not received the influence of mass media do not receive the influence of mass media even though they are connected to people in the society, and their opinions are about −40 and the trajectory of their opinions is horizontal. Even in that case, many people’s opinions are moving in the direction influenced by the mass media, that is, in the positive direction, because of the connections between people in society, even if the influence of the mass media does not reach them.
On the other hand, when people are closely connected in random networks, as seen in the case of 30%, even those who are not reached by mass media influence reach consensus with those who are, indicating that opinions are moving in a positive direction influenced by mass media.
The Trust-Distrust Model takes into account not only trust and consensus among people in a society but also distrust and opposition among people. Thus, phenomena such as social division can be reproduced in the simulation. Social divisions are often caused by serious conflicts in society, which is different from the phenomenon calculated by the Bounded Confidence Model, in which there are multiple consensus opinions because the opinions are far apart. In this sense, the Trust-Distrust Model seems to be a more suitable opinion dynamics theory for dealing with social fragmentation and division.
The most typical example of social division would be the American Civil War. The American society at that time was divided into two positions, and the war took the form of a war between two uncompromising and polarized groups. Another example would be the Reformation in Europe in the 16th century. Modern American society also seems to be divided into conservative and liberal, as seen in the 2020 presidential election. In Japan, during the Meiji Restoration in the mid-19th century, Japanese society was divided into conservative and reformist factions, and there was a civil war that lasted over a year. In addition to the past examples of wars, many countries are divided over whether to prioritize medical countermeasures or minimize economic damage in response to the spread of COVID-19 today, for example. Such divisions of opinion in society cannot be handled by the Bounded Confidence Model, since they clearly disagree with each other and with the opinions of others.
In the bounded confidence model, people in the society are basically in a trust relationship. In the bounded confidence model, people in the society are basically in a trusting relationship, and the cause of the polarization of opinions is therefore not affected by distant opinions. In the bounded confidence model, people are not influenced by opinions that are too far apart from their own, so the distribution of opinions in society becomes multipolar and coalesces into multiple opinions [10, 11].
However, in the case of the Trust-Distrust Model, it can be assumed that people in a society are divided into, say, two groups, and the groups are in conflict with each other and distrust each other. Figure 12 shows the polarization of opinions in the bounded confidence model and in the trust-distrust model. Figure 13 shows the polarization of opinions in the bounded confidence model and the trust-distrust model. Although they look the same, in the bounded confidence model, all people in society are bound by trust, while in the trust-distrust model, people in society are divided by distrust.
In-group and out-group based on Tajfel’s proposal. TA and TB are the proportions of positive values of the coefficient of trust Dij within groups a and B, and TAB is the proportion of positive values of the coefficient of trust Dij between groups.
More generally, we think of a society as being divided into multiple endogroups. A distinction is made between the relations between people within an endogroup and the relations between an endogroup and people in another endogroup. Tajfel’s idea [32] is to describe the relationship between an in-group and another in-group as an out-group.
This polarization of social opinion based on the Trust-Distrust Model is expressed in the concept of In-group and Out-group proposed by Tajfel [32], and Figure 13 shows a schematic diagram of the opinions of people in society according to Tajfel’s concept. In Figure 14, TA and TB are the proportions of positive values of the coefficient of trust Dij within groups A and B, and TAB is the proportion of positive values of the coefficient of trust Dij between groups. If TAB = 0, then the two groups are completely split as in Figure 13 (b).
Two typical examples of the distribution of opinions in a divided society. (a), TA = TB = 0.8. TAB = 0. Group A and Group B form a consensus as In-group. However, with TAB = 0. (b), TA = TB = 0.5. TAB = 0.
Figure 14 shows two typical examples of the distribution of opinions in a divided society. In (a), TA = TB = 0.8. TAB = 0. Group A and Group B form a consensus as In-group. However, with TAB = 0, the trust between the groups is zero. On the other hand, in (b), TA = TB = 0.5. TAB = 0, Group A and Group B do not form a consensus because of insufficient trust in the group, but the trajectories of the two groups are repulsive and do not mix because of distrust in the Out-group.
A typical example of (a) in Figure 14 would be the American Civil War, where society was completely divided, and war broke out. However, as far as the votes for the 2020 presidential election in the United States are concerned, the two candidates are competing in each state, and there is no regional division.
Figure 15 shows the results when TA and TB are fixed at 0.55 and TAB is varied. Here, TAB is not zero, so even with TAB = 0.3, Group A, and Group B mix a little. When TAB = 0.8, the two groups are in an out-group trust relationship, and they form a single consensus. For these detailed calculations, please refer to References [33, 34].
Calculations using the trust-distrust model when society is divided into Group A and Group B. TA = TB = 0.55. TAB = 0.3, 0.5, 0.6, 0.8. The opinion trajectories of people in Group A are in red and those of people in Group B are in blue.
In this paper, we introduced a new theory of opinion dynamics, the Trust-Distrust Model. Trust and mistrust play a very important role in this opinion dynamics theory. Trust brings people to a consensus, while distrust makes people repel. The Trust-Distrust Model is a theory that is suitable for simulating this situation.
The Bounded Confidence Model is a theory of opinion dynamics in which opinions take continuous values, and the Trust-Distrust Model is an extension of the Bounded Confidence Model. The Trust-Distrust Model is an extension of the Bounded Confidence Model in two respects: the coefficient Dij is seen as the coefficient of trust between people, and when this value is negative, the relationship is distrustful. Also, the influence of mass media was incorporated as an external field to the differential equation that determines opinion. The extension of distrust as negative trust facilitates the simulation of social phenomena such as social divisions. It is possible to simulate consensus building as an In-group for each group in the society, and trust and distrust as Out-group among groups in detail. In this sense, the Trust-Distrust Model is a theory that facilitates the simulation of a real, complex society. The main theme of this paper is the consensus of information: “trust-distrust”, the discussion of social impact through communication by various media formed by implicit understanding is represented by resistance to authority, populism, and risk. The focus tends to be on issues. Depending on the content and nature of the news, positive dissenting or agreeing opinions may have both similar and different tendencies depending on the source and content, and the ability of stakeholders to communicate in the discussion. The simulation results suggest that the network structure is significantly changed by the above. On SNS, we have already gradually introduced a mechanism to anticipate risks, such as (1) a mechanism to prohibit hackers from accessing the system with a system that is increasing in number mechanically, and (2) a mechanism to prohibit accounts due to posted content. Has been done. However, unpredictable behavior can occur. In addition, by accumulating information collectively, patterns for manipulating information will continue to grow. As mentioned above, in the 2020 US presidential election, strict regulations were imposed on large-scale web-based speech control and erroneous information transmission channels including bots. From this research, the network structure changes drastically due to the spread of erroneous information, the participation of untrustworthy information, the balance of the spread of reliable information, and the construction of the related party network, and the opinion is that phase transition occurs at a certain threshold. It was suggested. Significant changes may occur in the future due to future legislative decisions. Furthermore, we think that it is necessary to have a shared awareness not only of the crime clearance rate offline but also of security awareness in cyberspace as a social convention. In that respect as well, it is important to check facts in an online-offline environment and form a communication community in consideration of the reliability of information for a diverse risk society, or if it is distrustful for a risk society, it is wrong. It is necessary to consider various cases such as discussions when problems are overloaded, and it can be said that it is necessary to learn from past cases and prepare for them from hypothetical simulation results and case studies. In the future, there will be an increase in two-way communication across time and space by anonymizing personal information such as letters and pictograms, and extracting them “as cryptographic asset data” to represent social events. However, there are advantages and disadvantages to using information assets in the form of personalized data, which are excerpts of personal information as described above. In the future, the discussion of trust value in the above data will accelerate in indicators such as personal credit scoring. In this paper, the Trust-Distrust Model will be discussed with respect to theories that also address charismatic people, the effects of advertising, and social divisions. Furthermore, simulations of the Trust-Distrust Model show that 55% agreement is sufficient to build social consensus. By working on this theory, we hope to use it to discuss and predict social risk in future discussions in credit scoring.
This work is supported by JSPS KAKENHI Grant Number JP19K04881.
This is a brief overview of the main steps involved in publishing with IntechOpen Compacts, Monographs and Edited Books. Once you submit your proposal you will be appointed a Author Service Manager who will be your single point of contact and lead you through all the described steps below.
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Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"August 2nd, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:33,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:42,paginationItems:[{id:"82914",title:"Glance on the Critical Role of IL-23 Receptor Gene Variations in Inflammation-Induced Carcinogenesis",doi:"10.5772/intechopen.105049",signatures:"Mohammed El-Gedamy",slug:"glance-on-the-critical-role-of-il-23-receptor-gene-variations-in-inflammation-induced-carcinogenesis",totalDownloads:15,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}},{id:"82875",title:"Lipidomics as a Tool in the Diagnosis and Clinical Therapy",doi:"10.5772/intechopen.105857",signatures:"María Elizbeth Alvarez Sánchez, Erick Nolasco Ontiveros, Rodrigo Arreola, Adriana Montserrat Espinosa González, Ana María García Bores, Roberto Eduardo López Urrutia, Ignacio Peñalosa Castro, María del Socorro Sánchez Correa and Edgar Antonio Estrella Parra",slug:"lipidomics-as-a-tool-in-the-diagnosis-and-clinical-therapy",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82440",title:"Lipid Metabolism and Associated Molecular Signaling Events in Autoimmune Disease",doi:"10.5772/intechopen.105746",signatures:"Mohan Vanditha, Sonu Das and Mathew John",slug:"lipid-metabolism-and-associated-molecular-signaling-events-in-autoimmune-disease",totalDownloads:17,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82483",title:"Oxidative Stress in Cardiovascular Diseases",doi:"10.5772/intechopen.105891",signatures:"Laura Mourino-Alvarez, Tamara Sastre-Oliva, Nerea Corbacho-Alonso and Maria G. 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Waisundara",profilePictureURL:"https://mts.intechopen.com/storage/users/194281/images/system/194281.jpg",biography:"Dr. Viduranga Waisundara obtained her Ph.D. in Food Science\nand Technology from the Department of Chemistry, National\nUniversity of Singapore, in 2010. She was a lecturer at Temasek Polytechnic, Singapore from July 2009 to March 2013.\nShe relocated to her motherland of Sri Lanka and spearheaded the Functional Food Product Development Project at the\nNational Institute of Fundamental Studies from April 2013 to\nOctober 2016. She was a senior lecturer on a temporary basis at the Department of\nFood Technology, Faculty of Technology, Rajarata University of Sri Lanka. She is\ncurrently Deputy Principal of the Australian College of Business and Technology –\nKandy Campus, Sri Lanka. She is also the Global Harmonization Initiative (GHI)",institutionString:"Australian College of Business & Technology",institution:{name:"Kobe College",institutionURL:null,country:{name:"Japan"}}}]},{type:"book",id:"6820",title:"Keratin",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6820.jpg",slug:"keratin",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Miroslav Blumenberg",hash:"6def75cd4b6b5324a02b6dc0359896d0",volumeInSeries:2,fullTitle:"Keratin",editors:[{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}}]},{type:"book",id:"7978",title:"Vitamin A",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7978.jpg",slug:"vitamin-a",publishedDate:"May 15th 2019",editedByType:"Edited by",bookSignature:"Leila Queiroz Zepka, Veridiana Vera de Rosso and Eduardo Jacob-Lopes",hash:"dad04a658ab9e3d851d23705980a688b",volumeInSeries:3,fullTitle:"Vitamin A",editors:[{id:"261969",title:"Dr.",name:"Leila",middleName:null,surname:"Queiroz Zepka",slug:"leila-queiroz-zepka",fullName:"Leila Queiroz Zepka",profilePictureURL:"https://mts.intechopen.com/storage/users/261969/images/system/261969.png",biography:"Prof. Dr. Leila Queiroz Zepka is currently an associate professor in the Department of Food Technology and Science, Federal University of Santa Maria, Brazil. She has more than fifteen years of teaching and research experience. She has published more than 550 scientific publications/communications, including 15 books, 50 book chapters, 100 original research papers, 380 research communications in national and international conferences, and 12 patents. She is a member of the editorial board of five journals and acts as a reviewer for several national and international journals. Her research interests include microalgal biotechnology with an emphasis on microalgae-based products.",institutionString:"Universidade Federal de Santa Maria",institution:{name:"Universidade Federal de Santa Maria",institutionURL:null,country:{name:"Brazil"}}}]},{type:"book",id:"7953",title:"Bioluminescence",subtitle:"Analytical Applications and Basic Biology",coverURL:"https://cdn.intechopen.com/books/images_new/7953.jpg",slug:"bioluminescence-analytical-applications-and-basic-biology",publishedDate:"September 25th 2019",editedByType:"Edited by",bookSignature:"Hirobumi Suzuki",hash:"3a8efa00b71abea11bf01973dc589979",volumeInSeries:4,fullTitle:"Bioluminescence - Analytical Applications and Basic Biology",editors:[{id:"185746",title:"Dr.",name:"Hirobumi",middleName:null,surname:"Suzuki",slug:"hirobumi-suzuki",fullName:"Hirobumi Suzuki",profilePictureURL:"https://mts.intechopen.com/storage/users/185746/images/system/185746.png",biography:"Dr. Hirobumi Suzuki received his Ph.D. in 1997 from Tokyo Metropolitan University, Japan, where he studied firefly phylogeny and the evolution of mating systems. He is especially interested in the genetic differentiation pattern and speciation process that correlate to the flashing pattern and mating behavior of some fireflies in Japan. He then worked for Olympus Corporation, a Japanese manufacturer of optics and imaging products, where he was involved in the development of luminescence technology and produced a bioluminescence microscope that is currently being used for gene expression analysis in chronobiology, neurobiology, and developmental biology. Dr. Suzuki currently serves as a visiting researcher at Kogakuin University, Japan, and also a vice president of the Japan Firefly Society.",institutionString:"Kogakuin University",institution:null}]}]},openForSubmissionBooks:{paginationCount:2,paginationItems:[{id:"11474",title:"Quality of Life Interventions - Magnitude of Effect and Transferability",coverURL:"https://cdn.intechopen.com/books/images_new/11474.jpg",hash:"5a6bcdaf5ee144d043bcdab893ff9e1c",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 7th 2022",isOpenForSubmission:!0,editors:[{id:"245319",title:"Ph.D.",name:"Sage",surname:"Arbor",slug:"sage-arbor",fullName:"Sage Arbor"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11473",title:"Social Inequality - Structure and Social Processes",coverURL:"https://cdn.intechopen.com/books/images_new/11473.jpg",hash:"cefab077e403fd1695fb2946e7914942",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 13th 2022",isOpenForSubmission:!0,editors:[{id:"313341",title:"Ph.D.",name:"Yaroslava",surname:"Robles-Bykbaev",slug:"yaroslava-robles-bykbaev",fullName:"Yaroslava Robles-Bykbaev"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:49,paginationItems:[{id:"83087",title:"Role of Cellular Responses in Periodontal Tissue Destruction",doi:"10.5772/intechopen.106645",signatures:"Nam Cong-Nhat Huynh",slug:"role-of-cellular-responses-in-periodontal-tissue-destruction",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Periodontology - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11566.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"83073",title:"Dental and Orofacial Trauma Impacts on Oral-Health-Related—Quality of Life in Children: Low- and Middle-Income Countries",doi:"10.5772/intechopen.105845",signatures:"Yolanda Malele-Kolisa, Nazia Khan, Mpho P. 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He has both an MS and Ph.D. in Biomedical Engineering. He was previously a research scientist at the University of California Los Angeles (UCLA) and visiting professor and researcher at the University of North Dakota. He is currently working in artificial intelligence and its applications in medical signal processing. In addition, he is using digital signal processing in medical imaging and speech processing. Dr. Asadpour has developed brain-computer interfacing algorithms and has published books, book chapters, and several journal and conference papers in this field and other areas of intelligent signal processing. 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Ms. Mehtab has published seven papers in international conferences and one of her papers has been accepted for publication in a reputable international journal. She has won the best paper awards in two prestigious international conferences – BAICONF 2019, and ICADCML 2021, organized in the Indian Institute of Management, Bangalore, India in December 2019, and SOA University, Bhubaneswar, India in January 2021. Besides, Ms. Mehtab has also published two book chapters in two books. Seven of her book chapters will be published in a volume shortly in 2021 by Cambridge Scholars’ Press, UK. Currently, she is working as the joint editor of two edited volumes on Time Series Analysis and Forecasting to be published in the first half of 2021 by an international house. Currently, she is working as a Data Scientist with an MNC in Delhi, India.",institutionString:"NSHM College of Management and Technology",institution:{name:"Association for Computing Machinery",country:{name:"United States of America"}}},{id:"226240",title:"Dr.",name:"Andri Irfan",middleName:null,surname:"Rifai",slug:"andri-irfan-rifai",fullName:"Andri Irfan Rifai",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/226240/images/7412_n.jpg",biography:"Andri IRFAN is a Senior Lecturer of Civil Engineering and Planning. He completed the PhD at the Universitas Indonesia & Universidade do Minho with Sandwich Program Scholarship from the Directorate General of Higher Education and LPDP scholarship. He has been teaching for more than 19 years and much active to applied his knowledge in the project construction in Indonesia. His research interest ranges from pavement management system to advanced data mining techniques for transportation engineering. He has published more than 50 papers in journals and 2 books.",institutionString:null,institution:{name:"Universitas Internasional Batam",country:{name:"Indonesia"}}},{id:"314576",title:"Dr.",name:"Ibai",middleName:null,surname:"Laña",slug:"ibai-lana",fullName:"Ibai Laña",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314576/images/system/314576.jpg",biography:"Dr. Ibai Laña works at TECNALIA as a data analyst. He received his Ph.D. in Artificial Intelligence from the University of the Basque Country (UPV/EHU), Spain, in 2018. He is currently a senior researcher at TECNALIA. His research interests fall within the intersection of intelligent transportation systems, machine learning, traffic data analysis, and data science. He has dealt with urban traffic forecasting problems, applying machine learning models and evolutionary algorithms. He has experience in origin-destination matrix estimation or point of interest and trajectory detection. Working with large volumes of data has given him a good command of big data processing tools and NoSQL databases. He has also been a visiting scholar at the Knowledge Engineering and Discovery Research Institute, Auckland University of Technology.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"314575",title:"Dr.",name:"Jesus",middleName:null,surname:"L. Lobo",slug:"jesus-l.-lobo",fullName:"Jesus L. Lobo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314575/images/system/314575.png",biography:"Dr. Jesús López is currently based in Bilbao (Spain) working at TECNALIA as Artificial Intelligence Research Scientist. In most cases, a project idea or a new research line needs to be investigated to see if it is good enough to take into production or to focus on it. That is exactly what he does, diving into Machine Learning algorithms and technologies to help TECNALIA to decide whether something is great in theory or will actually impact on the product or processes of its projects. So, he is expert at framing experiments, developing hypotheses, and proving whether they’re true or not, in order to investigate fundamental problems with a longer time horizon. He is also able to design and develop PoCs and system prototypes in simulation. He has participated in several national and internacional R&D projects.\n\nAs another relevant part of his everyday research work, he usually publishes his findings in reputed scientific refereed journals and international conferences, occasionally acting as reviewer and Programme Commitee member. Concretely, since 2018 he has published 9 JCR (8 Q1) journal papers, 9 conference papers (e.g. ECML PKDD 2021), and he has co-edited a book. He is also active in popular science writing data science stories for reputed blogs (KDNuggets, TowardsDataScience, Naukas). Besides, he has recently embarked on mentoring programmes as mentor, and has also worked as data science trainer.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"103779",title:"Prof.",name:"Yalcin",middleName:null,surname:"Isler",slug:"yalcin-isler",fullName:"Yalcin Isler",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRyQ8QAK/Profile_Picture_1628834958734",biography:"Yalcin Isler (1971 - Burdur / Turkey) received the B.Sc. degree in the Department of Electrical and Electronics Engineering from Anadolu University, Eskisehir, Turkey, in 1993, the M.Sc. degree from the Department of Electronics and Communication Engineering, Suleyman Demirel University, Isparta, Turkey, in 1996, the Ph.D. degree from the Department of Electrical and Electronics Engineering, Dokuz Eylul University, Izmir, Turkey, in 2009, and the Competence of Associate Professorship from the Turkish Interuniversity Council in 2019.\n\nHe was Lecturer at Burdur Vocational School in Suleyman Demirel University (1993-2000, Burdur / Turkey), Software Engineer (2000-2002, Izmir / Turkey), Research Assistant in Bulent Ecevit University (2002-2003, Zonguldak / Turkey), Research Assistant in Dokuz Eylul University (2003-2010, Izmir / Turkey), Assistant Professor at the Department of Electrical and Electronics Engineering in Bulent Ecevit University (2010-2012, Zonguldak / Turkey), Assistant Professor at the Department of Biomedical Engineering in Izmir Katip Celebi University (2012-2019, Izmir / Turkey). He is an Associate Professor at the Department of Biomedical Engineering at Izmir Katip Celebi University, Izmir / Turkey, since 2019. In addition to academics, he has also founded Islerya Medical and Information Technologies Company, Izmir / Turkey, since 2017.\n\nHis main research interests cover biomedical signal processing, pattern recognition, medical device design, programming, and embedded systems. He has many scientific papers and participated in several projects in these study fields. He was an IEEE Student Member (2009-2011) and IEEE Member (2011-2014) and has been IEEE Senior Member since 2014.",institutionString:null,institution:{name:"Izmir Kâtip Çelebi University",country:{name:"Turkey"}}},{id:"339677",title:"Dr.",name:"Mrinmoy",middleName:null,surname:"Roy",slug:"mrinmoy-roy",fullName:"Mrinmoy Roy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/339677/images/16768_n.jpg",biography:"An accomplished Sales & Marketing professional with 12 years of cross-functional experience in well-known organisations such as CIPLA, LUPIN, GLENMARK, ASTRAZENECA across different segment of Sales & Marketing, International Business, Institutional Business, Product Management, Strategic Marketing of HIV, Oncology, Derma, Respiratory, Anti-Diabetic, Nutraceutical & Stomatological Product Portfolio and Generic as well as Chronic Critical Care Portfolio. A First Class MBA in International Business & Strategic Marketing, B.Pharm, D.Pharm, Google Certified Digital Marketing Professional. Qualified PhD Candidate in Operations and Management with special focus on Artificial Intelligence and Machine Learning adoption, analysis and use in Healthcare, Hospital & Pharma Domain. Seasoned with diverse therapy area of Pharmaceutical Sales & Marketing ranging from generating revenue through generating prescriptions, launching new products, and making them big brands with continuous strategy execution at the Physician and Patients level. Moved from Sales to Marketing and Business Development for 3.5 years in South East Asian Market operating from Manila, Philippines. Came back to India and handled and developed Brands such as Gluconorm, Lupisulin, Supracal, Absolut Woman, Hemozink, Fabiflu (For COVID 19), and many more. In my previous assignment I used to develop and execute strategies on Sales & Marketing, Commercialization & Business Development for Institution and Corporate Hospital Business portfolio of Oncology Therapy Area for AstraZeneca Pharma India Ltd. Being a Research Scholar and Student of ‘Operations Research & Management: Artificial Intelligence’ I published several pioneer research papers and book chapters on the same in Internationally reputed journals and Books indexed in Scopus, Springer and Ei Compendex, Google Scholar etc. Currently, I am launching PGDM Pharmaceutical Management Program in IIHMR Bangalore and spearheading the course curriculum and structure of the same. I am interested in Collaboration for Healthcare Innovation, Pharma AI Innovation, Future trend in Marketing and Management with incubation on Healthcare, Healthcare IT startups, AI-ML Modelling and Healthcare Algorithm based training module development. I am also an affiliated member of the Institute of Management Consultant of India, looking forward to Healthcare, Healthcare IT and Innovation, Pharma and Hospital Management Consulting works.",institutionString:null,institution:{name:"Lovely Professional University",country:{name:"India"}}},{id:"310576",title:"Prof.",name:"Erick Giovani",middleName:null,surname:"Sperandio Nascimento",slug:"erick-giovani-sperandio-nascimento",fullName:"Erick Giovani Sperandio Nascimento",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y00002pDKxDQAW/ProfilePicture%202022-06-20%2019%3A57%3A24.788",biography:"Prof. Erick Sperandio is the Lead Researcher and professor of Artificial Intelligence (AI) at SENAI CIMATEC, Bahia, Brazil, also working with Computational Modeling (CM) and HPC. He holds a PhD in Environmental Engineering in the area of Atmospheric Computational Modeling, a Master in Informatics in the field of Computational Intelligence and Graduated in Computer Science from UFES. He currently coordinates, leads and participates in R&D projects in the areas of AI, computational modeling and supercomputing applied to different areas such as Oil and Gas, Health, Advanced Manufacturing, Renewable Energies and Atmospheric Sciences, advising undergraduate, master's and doctoral students. He is the Lead Researcher at SENAI CIMATEC's Reference Center on Artificial Intelligence. In addition, he is a Certified Instructor and University Ambassador of the NVIDIA Deep Learning Institute (DLI) in the areas of Deep Learning, Computer Vision, Natural Language Processing and Recommender Systems, and Principal Investigator of the NVIDIA/CIMATEC AI Joint Lab, the first in Latin America within the NVIDIA AI Technology Center (NVAITC) worldwide program. He also works as a researcher at the Supercomputing Center for Industrial Innovation (CS2i) and at the SENAI Institute of Innovation for Automation (ISI Automação), both from SENAI CIMATEC. He is a member and vice-coordinator of the Basic Board of Scientific-Technological Advice and Evaluation, in the area of Innovation, of the Foundation for Research Support of the State of Bahia (FAPESB). He serves as Technology Transfer Coordinator and one of the Principal Investigators at the National Applied Research Center in Artificial Intelligence (CPA-IA) of SENAI CIMATEC, focusing on Industry, being one of the six CPA-IA in Brazil approved by MCTI / FAPESP / CGI.br. He also participates as one of the representatives of Brazil in the BRICS Innovation Collaboration Working Group on HPC, ICT and AI. He is the coordinator of the Work Group of the Axis 5 - Workforce and Training - of the Brazilian Strategy for Artificial Intelligence (EBIA), and member of the MCTI/EMBRAPII AI Innovation Network Training Committee. He is the coordinator, by SENAI CIMATEC, of the Artificial Intelligence Reference Network of the State of Bahia (REDE BAH.IA). He leads the working group of experts representing Brazil in the Global Partnership on Artificial Intelligence (GPAI), on the theme \"AI and the Pandemic Response\".",institutionString:"Manufacturing and Technology Integrated Campus – SENAI CIMATEC",institution:null},{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/1063/images/system/1063.png",biography:"Prof. Dr. Constantin Voloşencu graduated as an engineer from\nPolitehnica University of Timișoara, Romania, where he also\nobtained a doctorate degree. He is currently a full professor in\nthe Department of Automation and Applied Informatics at the\nsame university. Dr. Voloşencu is the author of ten books, seven\nbook chapters, and more than 160 papers published in journals\nand conference proceedings. He has also edited twelve books and\nhas twenty-seven patents to his name. He is a manager of research grants, editor in\nchief and member of international journal editorial boards, a former plenary speaker, a member of scientific committees, and chair at international conferences. His\nresearch is in the fields of control systems, control of electric drives, fuzzy control\nsystems, neural network applications, fault detection and diagnosis, sensor network\napplications, monitoring of distributed parameter systems, and power ultrasound\napplications. He has developed automation equipment for machine tools, spooling\nmachines, high-power ultrasound processes, and more.",institutionString:'"Politechnica" University Timişoara',institution:null},{id:"221364",title:"Dr.",name:"Eneko",middleName:null,surname:"Osaba",slug:"eneko-osaba",fullName:"Eneko Osaba",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/221364/images/system/221364.jpg",biography:"Dr. Eneko Osaba works at TECNALIA as a senior researcher. He obtained his Ph.D. in Artificial Intelligence in 2015. He has participated in more than twenty-five local and European research projects, and in the publication of more than 130 papers. He has performed several stays at universities in the United Kingdom, Italy, and Malta. Dr. Osaba has served as a program committee member in more than forty international conferences and participated in organizing activities in more than ten international conferences. He is a member of the editorial board of the International Journal of Artificial Intelligence, Data in Brief, and Journal of Advanced Transportation. He is also a guest editor for the Journal of Computational Science, Neurocomputing, Swarm, and Evolutionary Computation and IEEE ITS Magazine.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"275829",title:"Dr.",name:"Esther",middleName:null,surname:"Villar-Rodriguez",slug:"esther-villar-rodriguez",fullName:"Esther Villar-Rodriguez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/275829/images/system/275829.jpg",biography:"Dr. Esther Villar obtained a Ph.D. in Information and Communication Technologies from the University of Alcalá, Spain, in 2015. She obtained a degree in Computer Science from the University of Deusto, Spain, in 2010, and an MSc in Computer Languages and Systems from the National University of Distance Education, Spain, in 2012. Her areas of interest and knowledge include natural language processing (NLP), detection of impersonation in social networks, semantic web, and machine learning. Dr. Esther Villar made several contributions at conferences and publishing in various journals in those fields. Currently, she is working within the OPTIMA (Optimization Modeling & Analytics) business of TECNALIA’s ICT Division as a data scientist in projects related to the prediction and optimization of management and industrial processes (resource planning, energy efficiency, etc).",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"49813",title:"Dr.",name:"Javier",middleName:null,surname:"Del Ser",slug:"javier-del-ser",fullName:"Javier Del Ser",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49813/images/system/49813.png",biography:"Prof. Dr. Javier Del Ser received his first PhD in Telecommunication Engineering (Cum Laude) from the University of Navarra, Spain, in 2006, and a second PhD in Computational Intelligence (Summa Cum Laude) from the University of Alcala, Spain, in 2013. He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. He is a Senior Member of the IEEE, and a recipient of the Biscay Talent prize for his academic career.",institutionString:"Tecnalia Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"278948",title:"Dr.",name:"Carlos Pedro",middleName:null,surname:"Gonçalves",slug:"carlos-pedro-goncalves",fullName:"Carlos Pedro Gonçalves",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRcmyQAC/Profile_Picture_1564224512145",biography:'Carlos Pedro Gonçalves (PhD) is an Associate Professor at Lusophone University of Humanities and Technologies and a researcher on Complexity Sciences, Quantum Technologies, Artificial Intelligence, Strategic Studies, Studies in Intelligence and Security, FinTech and Financial Risk Modeling. He is also a progammer with programming experience in:\n\nA) Quantum Computing using Qiskit Python module and IBM Quantum Experience Platform, with software developed on the simulation of Quantum Artificial Neural Networks and Quantum Cybersecurity;\n\nB) Artificial Intelligence and Machine learning programming in Python;\n\nC) Artificial Intelligence, Multiagent Systems Modeling and System Dynamics Modeling in Netlogo, with models developed in the areas of Chaos Theory, Econophysics, Artificial Intelligence, Classical and Quantum Complex Systems Science, with the Econophysics models having been cited worldwide and incorporated in PhD programs by different Universities.\n\nReceived an Arctic Code Vault Contributor status by GitHub, due to having developed open source software preserved in the \\"Arctic Code Vault\\" for future generations (https://archiveprogram.github.com/arctic-vault/), with the Strategy Analyzer A.I. module for decision making support (based on his PhD thesis, used in his Classes on Decision Making and in Strategic Intelligence Consulting Activities) and QNeural Python Quantum Neural Network simulator also preserved in the \\"Arctic Code Vault\\", for access to these software modules see: https://github.com/cpgoncalves. He is also a peer reviewer with outsanding review status from Elsevier journals, including Physica A, Neurocomputing and Engineering Applications of Artificial Intelligence. Science CV available at: https://www.cienciavitae.pt//pt/8E1C-A8B3-78C5 and ORCID: https://orcid.org/0000-0002-0298-3974',institutionString:"University of Lisbon",institution:{name:"Universidade Lusófona",country:{name:"Portugal"}}},{id:"241400",title:"Prof.",name:"Mohammed",middleName:null,surname:"Bsiss",slug:"mohammed-bsiss",fullName:"Mohammed Bsiss",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241400/images/8062_n.jpg",biography:null,institutionString:null,institution:null},{id:"276128",title:"Dr.",name:"Hira",middleName:null,surname:"Fatima",slug:"hira-fatima",fullName:"Hira Fatima",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/276128/images/14420_n.jpg",biography:"Dr. Hira Fatima\nAssistant Professor\nDepartment of Mathematics\nInstitute of Applied Science\nMangalayatan University, Aligarh\nMobile: no : 8532041179\nhirafatima2014@gmal.com\n\nDr. Hira Fatima has received his Ph.D. degree in pure Mathematics from Aligarh Muslim University, Aligarh India. Currently working as an Assistant Professor in the Department of Mathematics, Institute of Applied Science, Mangalayatan University, Aligarh. She taught so many courses of Mathematics of UG and PG level. Her research Area of Expertise is Functional Analysis & Sequence Spaces. She has been working on Ideal Convergence of double sequence. She has published 17 research papers in National and International Journals including Cogent Mathematics, Filomat, Journal of Intelligent and Fuzzy Systems, Advances in Difference Equations, Journal of Mathematical Analysis, Journal of Mathematical & Computer Science etc. She has also reviewed few research papers for the and international journals. She is a member of Indian Mathematical Society.",institutionString:null,institution:null},{id:"414880",title:"Dr.",name:"Maryam",middleName:null,surname:"Vatankhah",slug:"maryam-vatankhah",fullName:"Maryam Vatankhah",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Borough of Manhattan Community College",country:{name:"United States of America"}}},{id:"414879",title:"Prof.",name:"Mohammad-Reza",middleName:null,surname:"Akbarzadeh-Totonchi",slug:"mohammad-reza-akbarzadeh-totonchi",fullName:"Mohammad-Reza Akbarzadeh-Totonchi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Ferdowsi University of Mashhad",country:{name:"Iran"}}},{id:"414878",title:"Prof.",name:"Reza",middleName:null,surname:"Fazel-Rezai",slug:"reza-fazel-rezai",fullName:"Reza Fazel-Rezai",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"American Public University System",country:{name:"United States of America"}}},{id:"426586",title:"Dr.",name:"Oladunni A.",middleName:null,surname:"Daramola",slug:"oladunni-a.-daramola",fullName:"Oladunni A. Daramola",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Federal University of Technology",country:{name:"Nigeria"}}},{id:"357014",title:"Prof.",name:"Leon",middleName:null,surname:"Bobrowski",slug:"leon-bobrowski",fullName:"Leon Bobrowski",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Bialystok University of Technology",country:{name:"Poland"}}},{id:"302698",title:"Dr.",name:"Yao",middleName:null,surname:"Shan",slug:"yao-shan",fullName:"Yao Shan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Dalian University of Technology",country:{name:"China"}}},{id:"354126",title:"Dr.",name:"Setiawan",middleName:null,surname:"Hadi",slug:"setiawan-hadi",fullName:"Setiawan Hadi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Padjadjaran University",country:{name:"Indonesia"}}},{id:"125911",title:"Prof.",name:"Jia-Ching",middleName:null,surname:"Wang",slug:"jia-ching-wang",fullName:"Jia-Ching Wang",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Central University",country:{name:"Taiwan"}}},{id:"332603",title:"Prof.",name:"Kumar S.",middleName:null,surname:"Ray",slug:"kumar-s.-ray",fullName:"Kumar S. Ray",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Indian Statistical Institute",country:{name:"India"}}},{id:"415409",title:"Prof.",name:"Maghsoud",middleName:null,surname:"Amiri",slug:"maghsoud-amiri",fullName:"Maghsoud Amiri",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Allameh Tabataba'i University",country:{name:"Iran"}}},{id:"357085",title:"Mr.",name:"P. Mohan",middleName:null,surname:"Anand",slug:"p.-mohan-anand",fullName:"P. Mohan Anand",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Indian Institute of Technology Kanpur",country:{name:"India"}}},{id:"356696",title:"Ph.D. Student",name:"P.V.",middleName:null,surname:"Sai Charan",slug:"p.v.-sai-charan",fullName:"P.V. Sai Charan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Indian Institute of Technology Kanpur",country:{name:"India"}}},{id:"357086",title:"Prof.",name:"Sandeep K.",middleName:null,surname:"Shukla",slug:"sandeep-k.-shukla",fullName:"Sandeep K. 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Thus all studies on metabolism will be considered for publication.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11413,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,series:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983"},editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",slug:"anca-pantea-stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",slug:"attilio-rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",slug:"yanfei-(jacob)-qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},onlineFirstChapters:{paginationCount:18,paginationItems:[{id:"82875",title:"Lipidomics as a Tool in the Diagnosis and Clinical Therapy",doi:"10.5772/intechopen.105857",signatures:"María Elizbeth Alvarez Sánchez, Erick Nolasco Ontiveros, Rodrigo Arreola, Adriana Montserrat Espinosa González, Ana María García Bores, Roberto Eduardo López Urrutia, Ignacio Peñalosa Castro, María del Socorro Sánchez Correa and Edgar Antonio Estrella Parra",slug:"lipidomics-as-a-tool-in-the-diagnosis-and-clinical-therapy",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - 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