Jindong Chen

Jindong Chen, Ph.D., AACR active member, Research Associate Professor, Laboratory Co-director, Department of Urology, University of Rochester Medical Center, New York, USA. He earned his Ph.D. in Karolinska Institute, Sweden. Then, he served as Research Scientist at Van Andel Research Institute, USA; Senior Scientist at National Cancer Centre Singapore and NUS-Duke University Graduate School. He has worked on colorectal carcinoma, breast cancer, and kidney cancer for more than 20 years. He identified two cancer-related genes, NORE1 and LSAMP by positional cloning strategy, and was awarded in the 94th AACR annual meeting. Afterward, he has successfully developed several FLCN and HRPT2 conditional knockout mouse models and was again awarded in the 100th AACR annual Meeting for generating a tumor-developing FLCN knockout mouse model. By using those mouse models, he has conducted quite a few anti-cancer drug tests.

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Latest work with IntechOpen by Jindong Chen

Summarizing a decade of scientific advance and therapeutic innovation, Renal Tumor offers all physicians treating kidney cancer, as well as researchers, updated information concerning the epidemiology, biology, and treatment of renal cell carcinoma. Contributors to this book are from all over the world and are experts in their individual fields. They have provided reviews about current knowledge in the management of both localized and metastatic renal cell carcinoma, as well as the latest developments in molecular genetics, imaging, and immune dysfunction associated with the diseases. Further special attention is paid to the biology of selected target molecules and various agents that inhibit these targets, including full chapters devoted to pharmaceutical drugs that selectively inhibit receptor tyrosine kinases, such as sunitinib and axitinib. Readers such as urological physicians, researchers, and kidney cancer patients are potential beneficiaries of this book.

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