Classifications of oronasal fistula.
\r\n\tGlobalization does not represent a pure and generous process for humanity or other species, but rather it implies social exclusion and also provokes situations of vulnerability in groups of people, forced exclusion, and apartheid: poor job opportunities, lack of access to education, worse socio-sanitary conditions. Specifically, it can be said that social segregation entails the apartheid of social groups of different ages, genders, and ethnicities; these groups live a reality manifested through the deepening of poverty, in terms of increased vulnerability of the poor and groups with little economic, social, cultural, labor and health stability.
\r\n\r\n\tThis book aims to talk about some topics that are neglected in the discourses of academic communities and political elites. The inequality process is deeply rooted among humans and is part of many people's lives in the form of modern apartheid, gender segregation, lack of health access, and cultural gap. All those structural inequality processes are the product of the biopower perpetuated and produced in the macrosystem, exosystem, mesosystem, and microsystem. For many people from the academy, the information-consuming public, and the society in general, it is a problem to talk about these processes, since they have either lost interest or have normalized the structural and social inequity. For this reason, we see it as transcendental to explain how this situation occurs from the most internal fibers to the most evident processes, intending to make it more visible and thus expose the situation for possible solutions.
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Axinte D.",authors:[{id:"23402",title:"Dr.",name:"Srinivas",middleName:null,surname:"Devadula",fullName:"Srinivas Devadula",slug:"srinivas-devadula"},{id:"23403",title:"Dr.",name:"Dragos",middleName:null,surname:"Axinte",fullName:"Dragos Axinte",slug:"dragos-axinte"}]},{id:"15105",title:"Ductile Mode Micro Laser Assisted Machining of Silicon Carbide",slug:"ductile-mode-micro-laser-assisted-machining-of-silicon-carbide",signatures:"Deepak Ravindra, Saurabh Virkar and John Patten",authors:[{id:"21605",title:"Dr.",name:"Deepak",middleName:null,surname:"Ravindra",fullName:"Deepak Ravindra",slug:"deepak-ravindra"},{id:"21773",title:"Dr.",name:"John",middleName:null,surname:"Patten",fullName:"John Patten",slug:"john-patten"},{id:"21774",title:"Mr.",name:"Saurabh",middleName:null,surname:"Virkar",fullName:"Saurabh Virkar",slug:"saurabh-virkar"},{id:"22753",title:"Mr",name:"Bogac",middleName:null,surname:"Poyraz",fullName:"Bogac Poyraz",slug:"bogac-poyraz"}]}]}],publishedBooks:[{type:"book",id:"9878",title:"Electromagnetic Wave Propagation for Industry and Biomedical Applications",subtitle:null,isOpenForSubmission:!1,hash:"e57ef4b5bada0d966637cd303d76278f",slug:"electromagnetic-wave-propagation-for-industry-and-biomedical-applications",bookSignature:"Lulu Wang",coverURL:"https://cdn.intechopen.com/books/images_new/9878.jpg",editedByType:"Edited by",editors:[{id:"257388",title:"Distinguished Prof.",name:"Lulu",surname:"Wang",slug:"lulu-wang",fullName:"Lulu Wang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10852",title:"Recent Topics in Electromagnetic Compatibility",subtitle:null,isOpenForSubmission:!1,hash:"f5d2cce3a2adbd5d108d3301ee97025b",slug:"recent-topics-in-electromagnetic-compatibility",bookSignature:"Ahmed Kishk",coverURL:"https://cdn.intechopen.com/books/images_new/10852.jpg",editedByType:"Edited by",editors:[{id:"150146",title:"Dr.",name:"Ahmed",surname:"Kishk",slug:"ahmed-kishk",fullName:"Ahmed Kishk"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"166",title:"Electromagnetic Waves",subtitle:null,isOpenForSubmission:!1,hash:"6561a39a2e8aaffc6cde23ecd65cdfde",slug:"electromagnetic-waves",bookSignature:"Vitaliy Zhurbenko",coverURL:"https://cdn.intechopen.com/books/images_new/166.jpg",editedByType:"Edited by",editors:[{id:"3721",title:"Prof.",name:"Vitaliy",surname:"Zhurbenko",slug:"vitaliy-zhurbenko",fullName:"Vitaliy Zhurbenko"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"415",title:"Behaviour of Electromagnetic Waves in Different Media and Structures",subtitle:null,isOpenForSubmission:!1,hash:"8496cd6f3c63a2b4d0b69076ec095343",slug:"behavior-of-electromagnetic-waves-in-different-media-and-structures",bookSignature:"Ali Akdagli",coverURL:"https://cdn.intechopen.com/books/images_new/415.jpg",editedByType:"Edited by",editors:[{id:"76005",title:"Prof.",name:"Ali",surname:"Akdagli",slug:"ali-akdagli",fullName:"Ali Akdagli"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2431",title:"Dielectric Material",subtitle:null,isOpenForSubmission:!1,hash:"70942e6b7ab8fb1bfa75537709d3910d",slug:"dielectric-material",bookSignature:"Marius Alexandru Silaghi",coverURL:"https://cdn.intechopen.com/books/images_new/2431.jpg",editedByType:"Edited by",editors:[{id:"128198",title:"Dr.",name:"Marius Alexandru",surname:"Silaghi",slug:"marius-alexandru-silaghi",fullName:"Marius Alexandru Silaghi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],publishedBooksByAuthor:[]},onlineFirst:{chapter:{type:"chapter",id:"79681",title:"Oronasal Fistula: A Complication of Cleft Palate Surgery",doi:"10.5772/intechopen.101205",slug:"oronasal-fistula-a-complication-of-cleft-palate-surgery",body:'Cleft lip and palate are among the most common birth defects in the craniofacial region [1]. The prevalence of isolated cleft palate is 1 in 2000 live births [2].
Management of children born with a cleft lip and/or palate necessitates long-term and multidisciplinary involvement and multidisciplinary to obtain the most satisfactory results [3].
In an attempt to correct such abnormality, non-surgical appliances, as well as surgical correction procedures, could be adopted for the affected individuals.
Following surgical correction, oronasal fistula constitutes the most common complication, which compromises the goal of palatoplasty [4], and is further considered (with other two additional complications, namely velopharyngeal insufficiency [VPI] and midface hypoplasia) as a metric and quality indicator [5].
In this chapter, oronasal fistula, as one of the expected deleterious outcomes of cleft palate surgery, is discussed thoroughly. Its definition, causes, classification, incidence, diagnosis, and management (both non-surgical and surgical treatment) are identified.
Generally, fistula refers to a communicating track between two epithelial surfaces, commonly between a hollow viscus and the skin (external fistula) or between two hollow viscera (internal fistula), lined with granulation tissue which is subsequently epithelized [6, 7]. Specifically, the nasal cavity is separated from the oral cavity anteriorly by the premaxilla and maxilla and posteriorly by the horizontal plate of the palatine bone [8]. The oronasal fistula (ONF) is an internal fistula and represents an abnormal epithelized track communicating between the nasal cavity and mouth [7].
There are many causes of fistulas of the hard palate that involve the nasal or antral cavities, or both [9]. Moreover, it is a known complication of cleft palate repair. Most commonly, sutures within the oral mucosa break down 1 week after surgery, leaving a local fissure at the surgical site in the oral cavity. This local fissure either eventually heals well after proper treatment or develops into a channel between the oral and nasal cavity, which is called an oronasal fistula, or ONF [10].
There is substantial variation in fistula incidence following surgical repair of cleft palate. Its occurrence is ranging widely, between 12 and 45%, as reported by Schultz in 1986 [11], and from 4–60% according to other studies. The occurrence of fistula following surgery is as high as 4–45%, which makes the cleft palate repair more challenging. Unfortunately, to date [12], there remains a wide range in frequency, which may be due to the absence of one agreed (unanimous) surgical technique, the application of different surgical techniques for cleft palate repair, the timing of the repair, the severity of the cleft and the surgeon’s experience. (Figure 1). Moreover, the current literature on fistula rates and surgical techniques is inconsistent [13].
Potential factors behind the wide difference in fistula rate following Palatoplasty.
Practically, surgical treatment of fistulas is often complicated by high recurrence rates (up to 33%), and further aggravated by multiple scars surrounding the lesion, which lead to more complicated recalcitrant fistulas [14].
Females’ patients are more frequently seen to be affected with CP [15]. However, oronasal fistulas after cleft palate repair seem to occur more commonly in males, for unknown reasons. Moreover, site-wise, Musgrave and Bremner’ found that the frequency of fistulas was significantly greater with bilateral cleft lip and palate than in unilateral cases [16].
The most common sites of fistulization are the hard palate and the transition between the hard and soft palates. However, it can also occur in the soft palate [17].
A systematic review published in 2017 by Reddy et al., showed that there was no conclusive evidence for the effects of one-stage versus two-stage palate repair on the frequency of fistulas [18]. Another study showed that there is no difference in the fistula rate in one-stage or two-stage palatoplasty [19], although recent accumulative data showed that a one-stage repair of the cleft palate is associated with a decreased risk of fistula formation compared to a two-stage repair [20].
Furlow’s technique is reported to be less prone to postoperative fistula than von Langenbeck and Veau/Wardill/Kilner techniques [20]. Furlow’s technique bases its principle on gaining length at the expense of width. Accordingly, the Furlow technique’s outcome is affected by the width as the only risk factor, as reported by Li et al. [21].
There are many causes for oronasal fistula, but the congenital cause in cleft palate patients (primary fistula) still remains the main etiology for oronasal fistulas [10].
The causes of fistula after palatoplasty (secondary fistula) may be precipitated by one of these factors (Figure 2):
Causes related to the nature of the cleft, such as the width of the cleft.
The amount of deficiency in the palate segments, as well as the misplacement and distortion of the cleft segment [22].
Causes related to the procedure and its sequelae, such as inadequate dissection of the flaps, closure under tension, post-operative bleeding, hematoma formation between the oral and nasal layers, and infection [23].
Potential causes of ONF following palatoplasty.
Oronasal fistula can be diagnosed depending on the criteria in the Figure 3 [7, 26].
Diagnostic criteria of Oronasal fistula.
Small palatal fistulas may not be symptomatic, so in many cases, surgical intervention is not justifiable, on the other hand, large palatal fistulas produce various symptoms [27]; These symptoms, may related to some extent to the site of the fistula, which can manifest themselves as nasality in speech, leakage of fluids into the nose, and food lodging in the defect; bad odors, bad tastes, as well as upper respiratory tract infections (Figure 4) [10, 23].
Oronasal fistula after palatoplasty.
The fistula may be present anywhere along the primary or secondary palate.
Palatal fistulae either being as:
A primary fistula associated with the clefting of the hard palate, or a
A secondary fistula may represent a failure of surgical techniques for the correction of cleft palate [4].
Numerous classification systems have been put forth over many years. But still, there is no agreed classification, examples of such classifications are Cohen et al. (1991) classification as well as Pittsburgh Fistula classification (Table 1) [12, 28, 29].
Classification’s Name | Classification’s Parameter | Description |
---|---|---|
Fistula’s site |
| |
Fistula’s site |
|
Classifications of oronasal fistula.
Unfortunately, both of them have helped in understanding the location of the fistula apart from putting guidance for the determination of the fistula’s difficulty.
Fistulas can be managed by prosthetic appliances such as obturators, but there are inherent problems with this approach, such as a sharp increase in the oral bacteria count, with a resultant increase in the incidence of dental caries. Moreover, it could not be considered as a definitive treatment [30].
Simple fistulas are successfully managed by local palatal flaps, but the success of such a way is limited in management in the situation of more complex fistulas [31, 32].
Treatment of the large fistulas is usually complex and difficult to be achieved by traditional local flaps. Accordingly, extensive palatal surgery and dissection are recommended.
Secondary repair of oronasoantral fistula (repair of the fistula many times) is one of the more challenging and difficult problems in the field of oral and maxillofacial.
Surgical closure can be fulfilled by more than one option such as; local flap, regional intraoral and extraoral flaps as well as a free flap [33].
Repeated attempts for the fistula closure followed by failure, may end up by local tissue scarring.
Alternative methods of the traditional local flap are reported in the literature:
Tongue flap, Guerrero-Santos, and Altamirano (1966) was first described the suitability of an anteriorly based dorsal tongue flap for repair of palatal fistulae [34], it can be attempted when other methods are not feasible, now it become widely accepted for the correction of the fistula following the failure of palatoplasty especially for the fistula with large size [23, 35, 36] it is a two-staged procedure and can be anteriorly or posteriorly depending on the fistula site with high success rate for the anterior fistulas [37].
The use of decellularized dermal grafting (Alloderm) in persistent oro-nasal fistulas is also reported in the literature [38].
Other surgical techniques that have been described include free flaps, tissue expansion, interposition grafts of (bone, free periosteum, or dermis-fat) [15].
In the literature, there is more than one adjunctive therapy to improve the surgical outcome, in oronasal fistula, such as
Antibiotic therapy [39]
A resorbable collagen membrane (inter-positional barrier [40] to be an adjunct to standard surgical care, with the objective of improving the stability of the soft tissue and decreasing the incidence of new dehiscence [14].
PDS, polydioxanone sheet, is a synthetic polyether-ester, which is an unstable biodegradable polymer [41].
Plasma rich in growth factors (PRGF) mixed with autologous bone graft [42]
Topical phenytoin 2% (for promotion of healing) [43].
Oronasal fistula is one of the great challenges in an oral and maxillofacial specialty, there is no conclusive evidence have determined its actual rate and there are wide ranges for its occurrence and no agreement on which procedure is being the most superior, with the low rate of fistula formation following palatoplasty. Both old literature and the recent one could not put a consensus to unifying terminology in the context of definition and classification for further reliable diagnosis in an attempt to find a more accepted, predictable outcome for preventing its occurrence and find optimal managing of recurrent ONF in cleft palate patients.
The author would like to thank Professor Ahmed Mohamed Suliman (Professor of Oral and Maxillofacial Surgery, Faculty of dentistry, Khartoum University, Sudan, for being the first supervisor of the author in the subspeciality of cleft lip and Palate in Sudanese Medical Specialization Board, and Thanks also for Dr. Haithem Babiker MD, DMD FACS, Craniomaxillofacial surgeon, University of Cincinnati Children’s Hospital, Ohio, USA, for his permission to attached the demonstrated picture.
Introduction
Definition
Incidence
3.1Fistula occurrence and fistula recurrence
3.2According to gender
3.3According to site
3.4According to the technique
3.4.1According to the stage technique
3.4.2According to the specific techniques
Causes
Diagnosis
5.1Diagnostic criteria
5.2Symptoms of oronasal Fistula
Classification
Management of the oronasal fistula
7.1Non-surgical treatment
7.2Surgical treatment
7.2.1Techniques used for correction of fistula
Adjunctive therapy
Conclusion
CP | Cleft Palate |
ONF | Oro nasal fistula |
VPI | Velopharyngeal Insufficiency |
PRGF | Plasma rich in growth factors |
PDS | polydioxanone sheet |
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\n\nUnless otherwise stated, IntechOpen and/or its licensors own the intellectual property rights for all materials on www.intechopen.com. All intellectual property rights are reserved. You may view, download, share, link and print pages from www.intechopen.com for your own personal use, subject to the restrictions set out in these Terms and Conditions.
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This is described by the well-known “Seebeck effect”. TE materials can convert also electricity into cooling through the “Peltier effect”. As such, TE materials and thermoelectric generator (TEG) devices can be utilized for potential applications including (i) thermal energy harvesting, (ii) local cooling and (iii) temperature sensing. The direct conversion of heat into electricity has been one of the most attractive solutions to the severe environmental and energy issues the humanity is coming across. This chapter covers the fundamental working principle of TE materials, the synthetic protocols for inorganic and organic thermoelectric materials, techniques and technologies for the fabrication of thermoelectric generators (otherwise defined as thermoelectric module devices) and a number of applications. Finally, future aspects and outlooks for further advancements at the “material” or “device” level for efficient power generation are remarked.",book:{id:"7626",slug:"advanced-thermoelectric-materials-for-energy-harvesting-applications",title:"Advanced Thermoelectric Materials for Energy Harvesting Applications",fullTitle:"Advanced Thermoelectric Materials for Energy Harvesting Applications"},signatures:"Lazaros Tzounis",authors:[{id:"288931",title:"Dr.",name:"Lazaros",middleName:null,surname:"Tzounis",slug:"lazaros-tzounis",fullName:"Lazaros Tzounis"}]},{id:"11874",doi:"10.5772/10128",title:"Some Chaotic Points in Cuprate Superconductors",slug:"some-chaotic-points-in-cuprate-superconductors",totalDownloads:2122,totalCrossrefCites:2,totalDimensionsCites:3,abstract:null,book:{id:"3573",slug:"superconductor",title:"Superconductor",fullTitle:"Superconductor"},signatures:"Özden Aslan Cataltepe",authors:null}],mostDownloadedChaptersLast30Days:[{id:"67825",title:"Organic Thermoelectrics and Thermoelectric Generators (TEGs)",slug:"organic-thermoelectrics-and-thermoelectric-generators-tegs-",totalDownloads:1259,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"Inorganic and organic thermoelectric (TE) materials have received an extensive scientific interest during the last decades, due to their ability to directly convert the thermal energy to electricity. This is described by the well-known “Seebeck effect”. TE materials can convert also electricity into cooling through the “Peltier effect”. As such, TE materials and thermoelectric generator (TEG) devices can be utilized for potential applications including (i) thermal energy harvesting, (ii) local cooling and (iii) temperature sensing. The direct conversion of heat into electricity has been one of the most attractive solutions to the severe environmental and energy issues the humanity is coming across. This chapter covers the fundamental working principle of TE materials, the synthetic protocols for inorganic and organic thermoelectric materials, techniques and technologies for the fabrication of thermoelectric generators (otherwise defined as thermoelectric module devices) and a number of applications. Finally, future aspects and outlooks for further advancements at the “material” or “device” level for efficient power generation are remarked.",book:{id:"7626",slug:"advanced-thermoelectric-materials-for-energy-harvesting-applications",title:"Advanced Thermoelectric Materials for Energy Harvesting Applications",fullTitle:"Advanced Thermoelectric Materials for Energy Harvesting Applications"},signatures:"Lazaros Tzounis",authors:[{id:"288931",title:"Dr.",name:"Lazaros",middleName:null,surname:"Tzounis",slug:"lazaros-tzounis",fullName:"Lazaros Tzounis"}]},{id:"11871",title:"X-ray Micro-Tomography as a New and Powerful Tool for Characterization of MgB2 Superconductor",slug:"x-ray-micro-tomography-as-a-tool-for-quantitative-characterization-of-mgb2-superconducting-materials",totalDownloads:2815,totalCrossrefCites:1,totalDimensionsCites:2,abstract:null,book:{id:"3573",slug:"superconductor",title:"Superconductor",fullTitle:"Superconductor"},signatures:"Gheorghe Aldica, Ion Tiseanu, Petre Badica, Teddy Craciunescu and Mattew Rindfleisch",authors:null},{id:"66134",title:"Heat Recovery and Power Generation Using Thermoelectric Generator",slug:"heat-recovery-and-power-generation-using-thermoelectric-generator",totalDownloads:1271,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"In this chapter, experimental analysis of the direct conversion of thermal energy into electric energy was carried out, in order to encourage the conscious use of energy and to reduce waste. The conversion of thermal energy into electrical energy occurs in a thermoelectric generator through the Seebeck effect. This effect is associated with the appearance of an electric potential difference between two different materials, placed in contact at different temperatures. This relation between temperature and electrical properties of the material is known as thermoelectricity. This experimental study has as objective the obtaining of operating characteristic curves of the thermoelectric generator TEG1-12611-6.0, for different temperature gradients and under constant pressure between the heater plate and the heat sink. Resistors were used to heat the thermoelectric generator, which simulates the residual heat, and insulation material to minimize the dissipation of heat to the environment. For cooling, a heat exchanger was used in order to maximize the temperature difference between the sides of the thermoelectric generator. In this way, it was possible to perform an experimental analysis of the obtained electric power for different temperature ranges between the faces of the generator and, with this, verify the applicability in real systems.",book:{id:"7626",slug:"advanced-thermoelectric-materials-for-energy-harvesting-applications",title:"Advanced Thermoelectric Materials for Energy Harvesting Applications",fullTitle:"Advanced Thermoelectric Materials for Energy Harvesting Applications"},signatures:"Luis Vitorio Gulineli Fachini, Pedro Leineker Ochoski Machado, Larissa Krambeck, Romeu Miqueias Szmoski and Thiago Antonini Alves",authors:[{id:"227996",title:"Prof.",name:"Thiago",middleName:null,surname:"Antonini Alves",slug:"thiago-antonini-alves",fullName:"Thiago Antonini Alves"},{id:"229395",title:"MSc.",name:"Larissa",middleName:null,surname:"Krambeck",slug:"larissa-krambeck",fullName:"Larissa Krambeck"},{id:"286032",title:"Mr.",name:"Luis Vitorio",middleName:null,surname:"Gulineli Fachini",slug:"luis-vitorio-gulineli-fachini",fullName:"Luis Vitorio Gulineli Fachini"},{id:"293535",title:"Mr.",name:"Pedro Leineker",middleName:null,surname:"Ochoski Machado",slug:"pedro-leineker-ochoski-machado",fullName:"Pedro Leineker Ochoski Machado"},{id:"293537",title:"Prof.",name:"Romeu",middleName:null,surname:"Miqueias Szmoski",slug:"romeu-miqueias-szmoski",fullName:"Romeu Miqueias Szmoski"}]},{id:"66622",title:"Thermoelectric Generator Using Passive Cooling",slug:"thermoelectric-generator-using-passive-cooling",totalDownloads:899,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"This chapter presents an analysis of a point-of-use thermoelectric generator that is patented by one of the authors. The design, implementation and performance of the generator for powering electronic monitoring devices and charging batteries is discussed. This passive generator has no moving parts and relies on ambient air cooling. In one iteration it produces 6.9 W of steady state power using six Laird thermoelectric modules (Laird PB23 Series, HT8, 12) when placed on a 160°C steam pipe with a 30°C ambient environment (\n\nΔ\nT\n\n of 130°C). The generator produced 31.2 volts (V) open circuit and 0.89 amperes (A) short circuit. It successfully powered two microcontroller-based security cameras, one with a wireless Local Area Network (LAN) and another with cellular connectivity. In another scenario, the generator produced approximately 6 W with a steam pipe temperature of 140°C and an ambient of 25°C (\n\nΔ\nT\n\n of 115°C). This second system powered LED lights, a cellular-interfaced video surveillance system, and monitoring robots, while simultaneously trickle charging batteries. A third installation totally powered a stand-alone 3G web security camera system.",book:{id:"7626",slug:"advanced-thermoelectric-materials-for-energy-harvesting-applications",title:"Advanced Thermoelectric Materials for Energy Harvesting Applications",fullTitle:"Advanced Thermoelectric Materials for Energy Harvesting Applications"},signatures:"Robert Dell, Michael Thomas Petralia, Ashish Pokharel and Runar Unnthorsson",authors:[{id:"86966",title:"Dr.",name:"Runar",middleName:null,surname:"Unnthorsson",slug:"runar-unnthorsson",fullName:"Runar Unnthorsson"},{id:"285210",title:"Prof.",name:"Robert",middleName:null,surname:"Dell",slug:"robert-dell",fullName:"Robert Dell"},{id:"294487",title:"MSc.",name:"Michael Thomas",middleName:null,surname:"Petralia",slug:"michael-thomas-petralia",fullName:"Michael Thomas Petralia"},{id:"294497",title:"BSc.",name:"Ashish",middleName:null,surname:"Pokharel",slug:"ashish-pokharel",fullName:"Ashish Pokharel"}]},{id:"67254",title:"Quantum Theory of the Seebeck Coefficient in YBCO",slug:"quantum-theory-of-the-seebeck-coefficient-in-ybco",totalDownloads:737,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The measured in-plane thermoelectric power (Seebeck coefficient) \n\n\nS\nab\n\n\n in YBCO below the superconducting temperature \n\n\nT\nc\n\n\n (\n\n∼\n\n94 K) \n\n\nS\nab\n\n\n is negative and \n\nT\n\n-independent. This is shown to arise from the fact that the “electrons” (minority carriers) having heavier mass contribute more to the thermoelectric power. The measured out-of-plane thermoelectric power \n\n\nS\nc\n\n\n rises linearly with the temperature \n\nT\n\n. This arises from moving bosonic pairons (Cooper pairs), the Bose-Einstein condensation (BEC) of which generates a supercurrent below \n\n\nT\nc\n\n\n. The center of mass of pairons moves as bosons. 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Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. 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Vikhe",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/323731/images/13613_n.jpg",biography:"Dr Deepak M.Vikhe .\n\n\t\n\tDr Deepak M.Vikhe , completed his Masters & PhD in Prosthodontics from Rural Dental College, Loni securing third rank in the Pravara Institute of Medical Sciences Deemed University. He was awarded Dr.G.C.DAS Memorial Award for Research on Implants at 39th IPS conference Dubai (U A E).He has two patents under his name. He has received Dr.Saraswati medal award for best research for implant study in 2017.He has received Fully funded scholarship to Spain ,university of Santiago de Compostela. He has completed fellowship in Implantlogy from Noble Biocare. \nHe has attended various conferences and CDE programmes and has national publications to his credit. His field of interest is in Implant supported prosthesis. Presently he is working as a associate professor in the Dept of Prosthodontics, Rural Dental College, Loni and maintains a successful private practice specialising in Implantology at Rahata.\n\nEmail: drdeepak_mvikhe@yahoo.com..................",institutionString:null,institution:{name:"Pravara Institute of Medical Sciences",country:{name:"India"}}},{id:"204110",title:"Dr.",name:"Ahmed A.",middleName:null,surname:"Madfa",slug:"ahmed-a.-madfa",fullName:"Ahmed A. Madfa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204110/images/system/204110.jpg",biography:"Dr. Madfa is currently Associate Professor of Endodontics at Thamar University and a visiting lecturer at Sana'a University and University of Sciences and Technology. He has more than 6 years of experience in teaching. His research interests include root canal morphology, functionally graded concept, dental biomaterials, epidemiology and dental education, biomimetic restoration, finite element analysis and endodontic regeneration. Dr. Madfa has numerous international publications, full articles, two patents, a book and a book chapter. Furthermore, he won 14 international scientific awards. Furthermore, he is involved in many academic activities ranging from editorial board member, reviewer for many international journals and postgraduate students' supervisor. Besides, I deliver many courses and training workshops at various scientific events. Dr. Madfa also regularly attends international conferences and holds administrative positions (Deputy Dean of the Faculty for Students’ & Academic Affairs and Deputy Head of Research Unit).",institutionString:"Thamar University",institution:null},{id:"210472",title:"Dr.",name:"Nermin",middleName:"Mohammed Ahmed",surname:"Yussif",slug:"nermin-yussif",fullName:"Nermin Yussif",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210472/images/system/210472.jpg",biography:"Dr. Nermin Mohammed Ahmed Yussif is working at the Faculty of dentistry, University for October university for modern sciences and arts (MSA). Her areas of expertise include: periodontology, dental laserology, oral implantology, periodontal plastic surgeries, oral mesotherapy, nutrition, dental pharmacology. She is an editor and reviewer in numerous international journals.",institutionString:"MSA University",institution:null},{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. He is also a Member of the Reviewer Board of International Journal of Dental Medicine (IJDM), and the Indian Journal of Conservative and Endodontics since 2016.",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",country:{name:"India"}}},{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null},{id:"178412",title:"Associate Prof.",name:"Guhan",middleName:null,surname:"Dergin",slug:"guhan-dergin",fullName:"Guhan Dergin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178412/images/6954_n.jpg",biography:"Assoc. Prof. Dr. Gühan Dergin was born in 1973 in Izmit. He graduated from Marmara University Faculty of Dentistry in 1999. He completed his specialty of OMFS surgery in Marmara University Faculty of Dentistry and obtained his PhD degree in 2006. In 2005, he was invited as a visiting doctor in the Oral and Maxillofacial Surgery Department of the University of North Carolina, USA, where he went on a scholarship. Dr. Dergin still continues his academic career as an associate professor in Marmara University Faculty of Dentistry. He has many articles in international and national scientific journals and chapters in books.",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"178414",title:"Prof.",name:"Yusuf",middleName:null,surname:"Emes",slug:"yusuf-emes",fullName:"Yusuf Emes",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178414/images/6953_n.jpg",biography:"Born in Istanbul in 1974, Dr. Emes graduated from Istanbul University Faculty of Dentistry in 1997 and completed his PhD degree in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery in 2005. He has papers published in international and national scientific journals, including research articles on implantology, oroantral fistulas, odontogenic cysts, and temporomandibular disorders. Dr. Emes is currently working as a full-time academic staff in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery.",institutionString:null,institution:{name:"Istanbul University",country:{name:"Turkey"}}},{id:"192229",title:"Ph.D.",name:"Ana Luiza",middleName:null,surname:"De Carvalho Felippini",slug:"ana-luiza-de-carvalho-felippini",fullName:"Ana Luiza De Carvalho Felippini",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192229/images/system/192229.jpg",biography:null,institutionString:"University of São Paulo",institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"256851",title:"Prof.",name:"Ayşe",middleName:null,surname:"Gülşen",slug:"ayse-gulsen",fullName:"Ayşe Gülşen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256851/images/9696_n.jpg",biography:"Dr. Ayşe Gülşen graduated in 1990 from Faculty of Dentistry, University of Ankara and did a postgraduate program at University of Gazi. \nShe worked as an observer and research assistant in Craniofacial Surgery Departments in New York, Providence Hospital in Michigan and Chang Gung Memorial Hospital in Taiwan. \nShe works as Craniofacial Orthodontist in Department of Aesthetic, Plastic and Reconstructive Surgery, Faculty of Medicine, University of Gazi, Ankara Turkey since 2004.",institutionString:"Univeristy of Gazi",institution:null},{id:"255366",title:"Prof.",name:"Tosun",middleName:null,surname:"Tosun",slug:"tosun-tosun",fullName:"Tosun Tosun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255366/images/7347_n.jpg",biography:"Graduated at the Faculty of Dentistry, University of Istanbul, Turkey in 1989;\nVisitor Assistant at the University of Padua, Italy and Branemark Osseointegration Center of Treviso, Italy between 1993-94;\nPhD thesis on oral implantology in University of Istanbul and was awarded the academic title “Dr.med.dent.”, 1997;\nHe was awarded the academic title “Doç.Dr.” (Associated Professor) in 2003;\nProficiency in Botulinum Toxin Applications, Reading-UK in 2009;\nMastership, RWTH Certificate in Laser Therapy in Dentistry, AALZ-Aachen University, Germany 2009-11;\nMaster of Science (MSc) in Laser Dentistry, University of Genoa, Italy 2013-14.\n\nDr.Tosun worked as Research Assistant in the Department of Oral Implantology, Faculty of Dentistry, University of Istanbul between 1990-2002. \nHe worked part-time as Consultant surgeon in Harvard Medical International Hospitals and John Hopkins Medicine, Istanbul between years 2007-09.\u2028He was contract Professor in the Department of Surgical and Diagnostic Sciences (DI.S.C.), Medical School, University of Genova, Italy between years 2011-16. \nSince 2015 he is visiting Professor at Medical School, University of Plovdiv, Bulgaria. \nCurrently he is Associated Prof.Dr. at the Dental School, Oral Surgery Dept., Istanbul Aydin University and since 2003 he works in his own private clinic in Istanbul, Turkey.\u2028\nDr.Tosun is reviewer in journal ‘Laser in Medical Sciences’, reviewer in journal ‘Folia Medica\\', a Fellow of the International Team for Implantology, Clinical Lecturer of DGZI German Association of Oral Implantology, Expert Lecturer of Laser&Health Academy, Country Representative of World Federation for Laser Dentistry, member of European Federation of Periodontology, member of Academy of Laser Dentistry. Dr.Tosun presents papers in international and national congresses and has scientific publications in international and national journals. He speaks english, spanish, italian and french.",institutionString:null,institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",biography:"Zühre Akarslan was born in 1977 in Cyprus. She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"256417",title:"Associate Prof.",name:"Sanaz",middleName:null,surname:"Sadry",slug:"sanaz-sadry",fullName:"Sanaz Sadry",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256417/images/8106_n.jpg",biography:null,institutionString:null,institution:null},{id:"272237",title:"Dr.",name:"Pinar",middleName:"Kiymet",surname:"Karataban",slug:"pinar-karataban",fullName:"Pinar Karataban",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/272237/images/8911_n.png",biography:"Assist.Prof.Dr.Pınar Kıymet Karataban, DDS PhD \n\nDr.Pınar Kıymet Karataban was born in Istanbul in 1975. After her graduation from Marmara University Faculty of Dentistry in 1998 she started her PhD in Paediatric Dentistry focused on children with special needs; mainly children with Cerebral Palsy. She finished her pHD thesis entitled \\'Investigation of occlusion via cast analysis and evaluation of dental caries prevalance, periodontal status and muscle dysfunctions in children with cerebral palsy” in 2008. She got her Assist. Proffessor degree in Istanbul Aydın University Paediatric Dentistry Department in 2015-2018. ın 2019 she started her new career in Bahcesehir University, Istanbul as Head of Department of Pediatric Dentistry. In 2020 she was accepted to BAU International University, Batumi as Professor of Pediatric Dentistry. She’s a lecturer in the same university meanwhile working part-time in private practice in Ege Dental Studio (https://www.egedisklinigi.com/) a multidisciplinary dental clinic in Istanbul. Her main interests are paleodontology, ancient and contemporary dentistry, oral microbiology, cerebral palsy and special care dentistry. She has national and international publications, scientific reports and is a member of IAPO (International Association for Paleodontology), IADH (International Association of Disability and Oral Health) and EAPD (European Association of Pediatric Dentistry).",institutionString:null,institution:null},{id:"202198",title:"Dr.",name:"Buket",middleName:null,surname:"Aybar",slug:"buket-aybar",fullName:"Buket Aybar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202198/images/6955_n.jpg",biography:"Buket Aybar, DDS, PhD, was born in 1971. She graduated from Istanbul University, Faculty of Dentistry, in 1992 and completed her PhD degree on Oral and Maxillofacial Surgery in Istanbul University in 1997.\nDr. Aybar is currently a full-time professor in Istanbul University, Faculty of Dentistry Department of Oral and Maxillofacial Surgery. She has teaching responsibilities in graduate and postgraduate programs. Her clinical practice includes mainly dentoalveolar surgery.\nHer topics of interest are biomaterials science and cell culture studies. She has many articles in international and national scientific journals and chapters in books; she also has participated in several scientific projects supported by Istanbul University Research fund.",institutionString:null,institution:null},{id:"260116",title:"Dr.",name:"Mehmet",middleName:null,surname:"Yaltirik",slug:"mehmet-yaltirik",fullName:"Mehmet Yaltirik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/260116/images/7413_n.jpg",biography:"Birth Date 25.09.1965\r\nBirth Place Adana- Turkey\r\nSex Male\r\nMarrial Status Bachelor\r\nDriving License Acquired\r\nMother Tongue Turkish\r\n\r\nAddress:\r\nWork:University of Istanbul,Faculty of Dentistry, Department of Oral Surgery and Oral Medicine 34093 Capa,Istanbul- TURKIYE",institutionString:null,institution:null},{id:"172009",title:"Dr.",name:"Fatma Deniz",middleName:null,surname:"Uzuner",slug:"fatma-deniz-uzuner",fullName:"Fatma Deniz Uzuner",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/172009/images/7122_n.jpg",biography:"Dr. Deniz Uzuner was born in 1969 in Kocaeli-TURKEY. After graduating from TED Ankara College in 1986, she attended the Hacettepe University, Faculty of Dentistry in Ankara. \nIn 1993 she attended the Gazi University, Faculty of Dentistry, Department of Orthodontics for her PhD education. After finishing the PhD education, she worked as orthodontist in Ankara Dental Hospital under the Turkish Government, Ministry of Health and in a special Orthodontic Clinic till 2011. Between 2011 and 2016, Dr. Deniz Uzuner worked as a specialist in the Department of Orthodontics, Faculty of Dentistry, Gazi University in Ankara/Turkey. In 2016, she was appointed associate professor. Dr. Deniz Uzuner has authored 23 Journal Papers, 3 Book Chapters and has had 39 oral/poster presentations. She is a member of the Turkish Orthodontic Society. Her knowledge of English is at an advanced level.",institutionString:null,institution:null},{id:"332914",title:"Dr.",name:"Muhammad Saad",middleName:null,surname:"Shaikh",slug:"muhammad-saad-shaikh",fullName:"Muhammad Saad Shaikh",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Jinnah Sindh Medical University",country:{name:"Pakistan"}}},{id:"315775",title:"Dr.",name:"Feng",middleName:null,surname:"Luo",slug:"feng-luo",fullName:"Feng Luo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sichuan University",country:{name:"China"}}},{id:"423519",title:"Dr.",name:"Sizakele",middleName:null,surname:"Ngwenya",slug:"sizakele-ngwenya",fullName:"Sizakele Ngwenya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419270",title:"Dr.",name:"Ann",middleName:null,surname:"Chianchitlert",slug:"ann-chianchitlert",fullName:"Ann Chianchitlert",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419271",title:"Dr.",name:"Diane",middleName:null,surname:"Selvido",slug:"diane-selvido",fullName:"Diane Selvido",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419272",title:"Dr.",name:"Irin",middleName:null,surname:"Sirisoontorn",slug:"irin-sirisoontorn",fullName:"Irin Sirisoontorn",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"355660",title:"Dr.",name:"Anitha",middleName:null,surname:"Mani",slug:"anitha-mani",fullName:"Anitha Mani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"355612",title:"Dr.",name:"Janani",middleName:null,surname:"Karthikeyan",slug:"janani-karthikeyan",fullName:"Janani Karthikeyan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"334400",title:"Dr.",name:"Suvetha",middleName:null,surname:"Siva",slug:"suvetha-siva",fullName:"Suvetha Siva",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}}]}},subseries:{item:{id:"20",type:"subseries",title:"Animal Nutrition",keywords:"Sustainable Animal Diets, Carbon Footprint, Meta Analyses",scope:"An essential part of animal production is nutrition. Animals need to receive a properly balanced diet. One of the new challenges we are now faced with is sustainable animal diets (STAND) that involve the 3 P’s (People, Planet, and Profitability). We must develop animal feed that does not compete with human food, use antibiotics, and explore new growth promoters options, such as plant extracts or compounds that promote feed efficiency (e.g., monensin, oils, enzymes, probiotics). These new feed options must also be environmentally friendly, reducing the Carbon footprint, CH4, N, and P emissions to the environment, with an adequate formulation of nutrients.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/20.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11416,editor:{id:"175967",title:"Dr.",name:"Manuel",middleName:null,surname:"Gonzalez Ronquillo",slug:"manuel-gonzalez-ronquillo",fullName:"Manuel Gonzalez Ronquillo",profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",biography:"Dr. Manuel González Ronquillo obtained his doctorate degree from the University of Zaragoza, Spain, in 2001. He is a research professor at the Faculty of Veterinary Medicine and Animal Husbandry, Autonomous University of the State of Mexico. He is also a level-2 researcher. He received a Fulbright-Garcia Robles fellowship for a postdoctoral stay at the US Dairy Forage Research Center, Madison, Wisconsin, USA in 2008–2009. He received grants from Alianza del Pacifico for a stay at the University of Magallanes, Chile, in 2014, and from Consejo Nacional de Ciencia y Tecnología (CONACyT) to work in the Food and Agriculture Organization’s Animal Production and Health Division (AGA), Rome, Italy, in 2014–2015. He has collaborated with researchers from different countries and published ninety-eight journal articles. 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