Diploid yeast strains used in this work.
\\n\\n
More than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\\n\\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\\n\\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\\n\\nAdditionally, each book published by IntechOpen contains original content and research findings.
\\n\\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\\n\\n\\n\\n
\\n"}]',published:!0,mainMedia:null},components:[{type:"htmlEditorComponent",content:'
Simba Information has released its Open Access Book Publishing 2020 - 2024 report and has again identified IntechOpen as the world’s largest Open Access book publisher by title count.
\n\nSimba Information is a leading provider for market intelligence and forecasts in the media and publishing industry. The report, published every year, provides an overview and financial outlook for the global professional e-book publishing market.
\n\nIntechOpen, De Gruyter, and Frontiers are the largest OA book publishers by title count, with IntechOpen coming in at first place with 5,101 OA books published, a good 1,782 titles ahead of the nearest competitor.
\n\nSince the first Open Access Book Publishing report published in 2016, IntechOpen has held the top stop each year.
\n\n\n\nMore than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\n\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\n\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\n\nAdditionally, each book published by IntechOpen contains original content and research findings.
\n\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\n\n\n\n
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The French microbiologist Henry Boulard isolated in 1923 a yeast strain (later named after him) after observing natives in Indochina affected by digestive disorders to chew litchi and mangosteen skins. It was said (but never proven) that those people could even protect themselves thereby against outbreaks of cholera.
\nEver since, there has been an increasing body of medical reports addressing the beneficial properties of Saccharomyces boulardii as a probiotic to treat cases of diarrhea, reconstituting the gut flora after antibiotic treatment and even in the treatment of patients suffering from Helicobacter pylori that can cause stomach ulcers (for a recent review, see [1]). High doses of lyophilized living cells (2–5 × 109) are administered in pills that dissolve in the gastrointestinal tract. It is assumed that S. boulardii cells do not establish in the gastrointestinal tract and are secreted with the feces. Therefore, several doses are recommended to be taken during several days. It has not been clearly shown if on their passage yeast cells interact with other microorganisms in the gastrointestinal tract. Despite several clinical studies indicating beneficial effects of S. boulardii, there have been also reports identifying it as the cause of fungemia in hospital patients (adults and children) that had received doses of this yeast to treat gastrointestinal disorders [2]. Though the beneficial effects of the baker’s yeast S. cerevisiae used for fermentation are unquestioned, certain wild S. cerevisiae isolates can have negative effects especially in people with a compromised immunosystem after undergoing surgery. Non-domesticated yeast strains as those isolated in hospitals can have invasive properties very different from those observed for domesticated yeast strains used in bakeries and breweries.
\nYeast strains used in the laboratory such as S288C are mostly derivatives of industrial yeast strains used for ages in breweries [3]. More recently, derivatives of diploid strain Σ1278b, which shows filamentous properties related to non-domesticated yeast strains [4], are used in molecular biology research. Surprisingly, the sequence identity of both yeast strains is only 46% [5] indicating considerable genetic variability due to adaptation to differing milieus and to human domestication of this eukaryotic species [6].
\nThanks to molecular genetic techniques, S. boulardii considered originally as a yeast species by itself [7] has been proven in recent years to be a variant of S. cerevisiae [8]. In this chapter, a diploid yeast strain similar to those strains used in most research laboratories, amenable to genetic manipulation when using conventional yeast protocols is shown.
\nTo further characterize this yeast, its growth properties at different temperatures are compared with other diploid yeast strains (all yeast strains used are summarized in Table 1). S. boulardii (I will keep this name in the text even though it is a S. cerevisiae strain) grows well on rich medium at 30°C as well as at 37°C but not at 40°C (Figure 1A). Growth at 37°C—though not ideal—is not uncommon to yeast strains such as the diploid strain BY4743 (a derivative of S288C) but as opposed to diploid strain RH2585/2586 (an Σ1278b derivative) which hardly grows at 37°C (Figure 1A). In that sense, growth at 37°C is not a particular and unique property of S. boulardii. It probably rather reflects its accommodation to hot climates such as those found often in Indochina.
\nName and properties of diploid yeast strain | \nAuxotrophic properties/antibiotic resistances | \n
---|---|
BY4743 | \nRequires histidine, leucine, methionine, and uracil | \n
RH2585/2586 | \nRequires histidine and uracil | \n
RH2585/2586 ∆flo8::kanX ∆flo8::NATR | \nNo requirements; G418- and NAT-resistant | \n
S. boulardii | \nNone | \n
S. boulardii ∆flo8::kanX ∆flo8::NATR | \nNo requirements; G418- and NAT-resistant | \n
S. boulardii ∆rem1::kanX ∆rem1::NATR | \nNo requirements; G418- and NAT-resistant | \n
S. boulardii ∆his3::kanX ∆his3::NATR | \nRequires histidine; G418- and NAT-resistant | \n
S. boulardii ∆ade2::kanX ∆ade2::NATR | \nRequires adenine; G418- and NAT-resistant | \n
Diploid yeast strains used in this work.
G418/geneticin and NAT/nourseothricin are selective antibiotics for yeast strains.
Properties of S. boulardii and other diploid yeast strains (all listed in Table 1). (A) Growth comparison of yeast strains at different temperatures. Indicated yeast strains were spread on YPD plates and incubated at indicated temperatures (30, 37, and 40°C) for 2 days; (B) filamentation properties of different yeast strains. Strains RH2585/2586, RH2585/2586 ∆flo8::kanX ∆flo8::NATR, and S. boulardii were incubated on SLAD plates (50 μM ammonium sulfate) for 1 day at 30°C and individual growth colony visualized under the microscope (upper panel: 20× magnification; lower panel: 100× magnification); (C) growth of S. boulardii on different media. S. boulardii (#1785) and derivatives ∆∆his3 (#1811) and ∆∆ade2 (#1812) were grown for 2 days at 30°C on minimal SD medium (left plate) or on YPD + G418 and nourseothricin (both at final 100 μg/ml) (right plate). Denote the characteristic pinkish color of strain #1812 due to the deletion of both ADE2 gene copies.
A further investigated property is S. boulardii’s potential capability to form filaments. For this purpose, it was grown on SLAD plates which carry only limiting concentrations of ammonium sulfate (50 μM, about 1000× less than conventional SD minimal medium). As observed under the microscope, the diploid strain RH2585/2586 clearly shows filamentous properties under such ammonium-limiting conditions (Figure 1B) [9]. Deletion of the FLO8 gene encoding a transcriptional factor required for filamentation and adhesion completely abolished its filamentous properties. Flo8 is required to express, for example, Flo11, a cell-surface glycoprotein [10]. As opposed to RH2585/2586, S. boulardii hardly showed any filamentation properties. Interestingly, sequencing of the PCR-amplified FLO8 gene of S. boulardii indicated that it does not carry a premature stop codon (not shown) found in non-filamentous yeast strains as those derived from S288C [10]. So, other up- or downstream genes required for filamentation are likely dysfunctional in S. boulardii. Its lack of filamentation probably explains its low toxicity and its lack of establishment capacity in the gastrointestinal tract that otherwise could make it more persistent and thereby more problematic for medical applications.
\nAnother interesting issue was to induce meiosis and sporulation in S. boulardii in order to obtain haploid progeny. For this purpose, diploid cells were incubated in a liquid medium with limiting nitrogen and very high potassium acetate concentration as a (poor) carbon source [11]. Despite several attempts, no tetrad formation was observed. In that respect, S. boulardii shows similar properties as RH2585/2586 (the filamentous diploid used in this work) that does not form tetrads upon treatment under the described conditions. In order to induce meiosis and sporulation, a double knockout of RME1 (Regulator of Meiosis 1) in S. boulardii was produced. RME1 is a negative regulator of meiosis that prevents the expression of meiosis-required proteins such as IME1 (Inducer of Meiosis 1) and promotes mitosis [12]. The S. boulardii ∆∆rme1 derivative did not show any phenotypical differences to the parental wild-type strain in terms of growth temperature (Figure 1A). Unfortunately, no tetrads were obtained from this knockout strain either. I conclude that S. boulardii does not undergo meiosis and haploid tetrad formation at least under laboratory conditions used here.
\nAs shown in Figure 1C, S. boulardii does not carry any auxotrophic markers as it grows well on minimal medium (SD) devoid of amino acids or nucleic acid components such as adenine or uracil. Auxotrophic marker genes could be easily obtained by deleting the ADE2 (adenine biosynthesis) or HIS3 (histidine biosynthesis) genes (Figure 1C). These deletions were obtained by introducing dominant auxotrophic marker genes that provide resistance to the antibiotics kanamycin/G418 or nourseothricin. Deletion of a single gene copy of ADE2 or HIS3 still allowed for growth on minimal medium plates (not shown) indicating the clear diploid character of this yeast. Only double deletion of both HIS3- or ADE2-gene copies (which made it resistant against both kanamycin/G418 and nourseothricin; Figure 1C) made this yeast strain auxotrophic for histidine or for adenine. Newly gained histidine auxotrophy was used in a subsequent experiment to transform it with yeast plasmids carrying HIS3 as a selectable marker gene (see subsequent text).
\nAs an auxotrophic histidine-deficient yeast strain was now available, I decided to transform it with conventional yeast plasmids that complement for the lack of HIS3. For this purpose, S. boulardii ∆∆his3 (#1811) was grown in minimal SD medium supplemented with histidine. Cells were made competent by treating them with Li-acetate following a well-established yeast transformation protocol [13].
\nAfter 2–3 days of incubation at 30°C, his+-transformants were nicely observed (Figure 2; left panel), indicating that a simple yeast transformation protocol was sufficient to transform this yeast strain and to recover its prototrophy. Plasmids used for transformation (p301HIS3 GAL-p20-HA from S. cerevisiae and Candida albicans) allow for the expression of the protein p20 (a modulator of the activity of eIF4E, the cap-binding protein; see subsequent text) when growing cells in a medium containing galactose. As shown on a Western Blot obtained from yeast extracts, p20 from different sources was expressed in galactose but not in glucose-containing media (Figure 2; right panel). This confirms that, in S. boulardii, the GAL1/10 promoter is regulated in an identical manner as in conventional yeast strains used in the laboratory [14].
\nTransformation of S. boulardii ∆∆his3 and expression of p20. (Left panel) Transformation of S. boulardii ∆∆his3. S. boulardii ∆∆his3 was transformed with plasmid p301HIS3 p20 (S. cerevisiae)-HA (segment 2) or with plasmid p301HIS3 p20 (C. albicans)-HA (segment 3) and grown on minimal medium plates (without histidine) for 3 days at 27°C. As a negative control, no plasmid DNA was added (segment 1); (right panel) expression of HA-tagged p20 after induction with galactose. S. boulardii ∆∆his3 extracts from cells transformed with p301HIS3 p20 (S. cerevisiae)-HA (lanes 1 and 3) or transformed with p301HIS3 p20 (C. albicans)-HA (lanes 2 and 4) grown on medium containing 2% glucose or 2% galactose as indicated are shown. Individual colonies from segments 2 and 3 were picked and grown in liquid SD medium for 24 h. Subsequently, half of the cells were collected, washed (2× with water), resuspended in SGal (minimal medium with 2% galactose), and incubated for 24 h at 27°C. Collected cells were boiled in 2× SDS-sample buffer, proteins separated on a 15% SDS-PAGE gel. Separated proteins were blotted onto nitrocellulose, subsequently incubated with monoclonal antibodies against the HA-tag (1:2000 Dilution in 2% skim milk). For visualization of the Western Blot, WesternBright ECL kit (advansta) was used.
p20, a small acidic protein of 161 amino acids, is encoded by the non-essential gene CAF20 which only exists in a variety of yeast species (such as S. glabrata, Kluyveromyces lactis, C. albicans, S. cerevisiae). Its function is related to regulating the activity of the cap-binding protein eIF4E during translation in a yet not-well-understood manner [15]. A sequence alignment of different yeast species (see Figure 3; upper panel) shows a clear homology but not identity of the corresponding p20 proteins. Especially conserved are peptide motifs at the amino terminus (which are required for binding to eIF4E; the canonical motif YxxxxLL/I/F highlighted) and at the carboxy terminus (where precise function has still to be determined).
\nSequence comparison of p20 from different yeast species. Multiple sequence alignment of p20 from different yeast sources (CANGA, Candida glabrata; KLUYV, Kluyveromyces lactis; CANAL, Candida albicans; YEAST, Saccharomyces cerevisiae) was done with the help of Clustal Omega (http://www.ebi.ac.uk/Tools/msa/clustalo/). Highlighted amino acids; see text. For sequencing of S. boulardii p20 gene, the complete ORF and adjacent sequences were PCR-amplified with oligonucleotides used for S. cerevisiae p20 gene amplification and the obtained PCR product was sequenced in both directions (shown is the part encoding the p20 open reading frame of S. boulardii).
The CAF20 gene from S. boulardii was PCR-amplified using genomic DNA and oligonucleotides hybridizing at the 5′ and 3′ region of the S. cerevisiae CAF20 gene. Subsequent sequencing showed that CAF20 from S. cerevisiae and S. boulardii is nearly identical. The only difference detected is a conserved amino acid substitution (leucine to valine; highlighted) at position 16 (Figure 3; lower panel). Among those yeast species that carry the p20 gene conservation varies between 30 and 90% (not shown). The almost identity of both sequences shown here clearly confirms that S. boulardii is a variant of the species S. cerevisiae.
\nIn this work, I present data indicating that S. boulardii is a diploid S. cerevisiae strain. It thrives well under laboratory conditions at different temperatures (up to 37°C) which is not unusual for different laboratory yeast strains. S. boulardii does not show filamentous properties even though its FLO8 gene does not carry the typical premature stop codon identified in many laboratory (and industrial) yeast strains. S. boulardii does not undergo meiosis or form haploid progeny when incubated in sporulation-inducing media. S. boulardii does not carry any identifiable auxotrophic gene markers. It can be easily manipulated to obtain knockout derivatives by inserting genes conferring antibiotic resistance and obtain thereby auxotrophic progeny. Additionally, S. boulardii can be easily transformed with conventional yeast plasmids allowing also for the expression of proteins regulated by the galactose-inducible GAL 1/10 yeast promoter.
\nIn accordance with those properties, it is probably not detrimental for human health (at least not for immunocompetent individuals) as it will not easily establish in the gut or penetrate the intestinal blood barrier. All this does not mean that it has beneficial physiological properties and I would like to ask the question: is this not just a further conventional yeast strain?
\nS. boulardii was obtained from I. M. Castro (Belo Horizonte/Brazil) [16]. I would like to thank Daniela Ross-Kaschitza from my laboratory for carefully reading this manuscript. This work was supported by the Swiss National Foundation grant 31003A_146722/1.
\nThe study of the thermal regime of various water areas is one of the most important oceanological problems, since the spatio-temporal variability of water temperature reflects complex processes of formation, transformation and dynamics of water masses. In addition, temperature is one of the key parameters that determine the conditions for the existence and development of most species of aquatic organisms; therefore, the study of this problem is also of key importance for hydrobiology. The zoning of water areas by the nature of temperature conditions, as well as their forecasting, taking into account the peculiarities of seasonal and interannual variability, is an important scientific task, which also has a pronounced applied aspect associated with the fact that accumulations of some species of commercial fish are confined to the zones of separation of water masses with different characteristics.
Direct measurements are a traditional source of water temperature data. Their accuracy depends only on the accuracy of the device, and the discreteness depends on the specific task (in some cases it can reach a fraction of a second). They can also be used to construct vertical profiles with high vertical resolution. However, recently the number of expeditions has been steadily declining, and the data obtained through direct measurements are point and irregular and are not suitable for studying large-scale phenomena or for obtaining data from hard-to-reach places.
Satellite data, on the other hand, are regular and allow covering the entire water area of the studied basin. Therefore, they are very good sources for studying seasonal and interannual variations in the temperature of the surface layer (the thickness of which ranges from 1 to 10 meters). The disadvantage of these data is the strong dependence of accuracy on cloudiness (especially in the infrared and visible ranges). Ideally, they should be regularly compared with direct measurements in order to identify errors in data interpretation.
For scientific purposes, data are usually used from satellites located either in a geosynchronous (in a particular case, geostationary orbit) or in a heliosynchronous orbit. The advantage of the geostationary orbit is obvious: you can get a picture of the same area with discreteness of up to half an hour, and after pointing to the satellite, a constant correction of the antenna position is not required. It is very useful for telecommunication systems as well as for obtaining meteorological data. The disadvantage is the lack of coverage at polar latitudes.
This disadvantage is easily eliminated by satellites in a polar sun-synchronous orbit. A sun-synchronous orbit is important to science because it keeps the angle of incidence of sunlight on the Earth’s surface more or less constant, although the angle will change with the change of seasons. Without a sun-synchronous orbit, you would have to account for changes in shadow and lighting angles, making it difficult to track changes over time. It would simply be impossible to collect the information needed to study climate change.
In 1997, a TeraScan satellite receiving station was installed at SakhNIRO, with the help of which data are received from the NOAA, Metop, Aqua and Terra satellites in a polar sun-synchronous orbit (Figure 1 [1]). At the moment, a 21-year series of satellite data on the temperature of the surface of the Sea of Okhotsk and adjacent waters has been accumulated, which makes it possible to analyze the interannual variations of this parameter.
Example of a sun-synchronous orbit for a NOAA satellite [1].
This chapter is organized as follows:
Section 2 discusses satellite data
Section 3 discusses Sea Surface Temperature (SST) anomalies
Section 4 analyzes long-term data series using linear regression
Section 5 presents results on periodic SST fluctuations
Section 6 concludes the chapter.
What is satellite data? An electromagnetic (EM) signal with certain characteristics leaves the sea and contains information about the primary observable quantities, which are light, radiation temperature, roughness and sea level. This signal travels through the atmosphere, where it can be distorted, and where noise is added to the signal before it is received by a sensor that registers certain properties of the radiation and converts each measurement into a digital signal to be encoded and sent back to earth. The sensor geometry limits each individual observation to a specific instantaneous field of view.
In order to convert a digital signal received at a ground station into a useful one for scientific measurements with a certain accuracy and quality, the process of obtaining data by the sensor should be numerically transformed using knowledge about signal processing technology, physical and technical properties of the sensor, the physics of the atmosphere, and the interaction of EM radiation with the ocean and near-surface processes in the ocean. The process of extracting data from a unique observation location in space is at the heart of the satellite data feature.
Table 1 summarizes 5 levels of satellite data processing.
Level | Product description |
---|---|
0 | Raw satellite data in binary format. |
1 | Image in measurement coordinates. Satellite data of individual calibrated channels. |
1,5 (or 1А) | In special cases, a Level 1 product with atmospheric correction applied. |
2 | Atmospheric corrected and calibrated product containing upstream values or directly variable ocean response with reference to geographic coordinates, but most often not mapped. |
3 | Composite images of the obtained ocean variables transferred to a standard map, obtained by averaging over space and time of several flights in the form of a level 2 product. This product contains data from only one sensor and may have gaps. |
4 | An image representing the ocean variable averaged within each cell of the spatio-temporal grid, for the creation of which the gaps in the level 3 product data are filled with data analysis methods, incl. Interpolation. In the course of the analysis, it is possible to use several level 2 or 3 products from different sensors, and it is also possible to use data from field observations or model calculations. |
A summary of various satellite data processing levels.
Using the TeraScan software, raw data received from satellites is automatically calibrated and atmospheric correction, as well as georeferencing of data and projection onto a standard map (selection of parameters, projections, etc., is performed once by the operator, after which it is performed in automatic mode). Then data with different spatial resolution (the maximum resolution for a set of satellites is 2 km, images with a spatial resolution of 250 m can be obtained on separate channels) are entered into the database, where the operator manually corrects each image (eliminates gross errors that most often appear in the case of the presence of semi-transparent clouds). After that, daily data averaging is performed. As the data accumulate, ten-day and monthly averaging is also performed (as shown in Figure 2 [2]), as well as the calculation of anomalies (deviations from the long-term average value in a specified decade or month, obtained over a number of previous years).
An example of a ten-day average image with a spatial resolution of 0.25 × 0.25 degrees (left) and 2 × 2 km (right) [2].
The resulting data set should be carefully analyzed. Determination of the characteristics of unidirectional trends, as well as the amplitudes and phases of cyclic components and the possibility of using them to predict thermal conditions in the next season constituting the content of this study.
There are two types of SST anomalies as for any parameter distributed in space and time. The first is the sharp deviation of the specified parameter from the mean values in the neighboring areas. Anomalies of this kind can be regular and even present on average long-term maps (Figure 3 [3]). Typical examples from the point of view of SST are upwelling zones (quasi-stationary), mouths of large rivers, as well as zones of influence of warm and cold currents. Some anomalies of this nature may be unstable and dependent on weather conditions. Such anomalies determine the behavior of aquatic organisms, since each species has its own conditions of existence and development (some species need colder water, and some are more comfortable in warmer water).
An example of the long-term average distribution of SST, the actual temperature in the second decade of July 2018 and the 2018 anomaly relative to the multi-year average (these conditions led to a two-week delay in the approach of pink salmon to spawning rivers) [3].
The second type of SST anomaly is a deviation from the multiyear average. This type of anomaly depends entirely on the current conditions and reflects the peculiarities of the distribution of the parameter in a given year. From the point of view of SST, this may mean more or less intense heating or cooling than usual. The appearance of such anomalies can lead to a change in the timing of the fish’s approach to spawning (Figure 3 [3]) or to migration to places with more favorable conditions, and in the early stages of development it can lead to death from unfavorable conditions.
Let us consider in more detail the extraordinary conditions that took place in the spring of 2011, when the greatest delay in the release of juveniles from the Sakhalin SFHs was noted. The spatial distributions of sea surface temperature anomalies observed during the period under consideration, which is strongly characterized by unusual conditions (Figure 4 [4]), are quite remarkable.
Distribution of surface temperature anomalies (°С) in the third decade of may (A) and in the second decade of June (B) 2011. Ice conditions off the east coast of Sakhalin Island (right) on June 2, 2011 (snapshot of the aqua satellite). The strait of Tatary is closed by heavy clouds [4].
In the third decade of May (Figure 4A), significant negative deviations from the norm were noted along the entire eastern coast of Sakhalin Island and in the Aniva Gulf; they were the largest (up to 3°C) in the basin of the Mordvinova Gulf. Judging by the zone of negative anomalies stretching from the Terpeniya Peninsula along the line of the depth increase, which corresponds to the core of the East Sakhalin Current [5], they were caused by the outflow of cold water and ice-cover remains from the northeastern shelf. This opinion is confirmed by a satellite image on June 2, 2011 (Figure 3 [3]), which clearly shows the transport of drifting ice from the north to the Terpeniya Peninsula and further towards the Mordvinova Gulf. Such a situation is observed relatively rarely: usually, under the influence of the southern winds characteristic of this period of the year, the ice that is transported from the Sakhalin Gulf is blocked at the northeastern tip of the island and does not move south of 52° N. A similar ice removal was observed in spring 2005 [6]. Then, due to the unusual distribution of the surface atmospheric pressure, the northeastern winds prevailed in the study region, which just contribute to the transport of drifting ice to the southeastern coast of Sakhalin Island, as well as to the estuarine regions of the Naiba and Ai rivers and to the Mordvinova Gulf.
In spring 2011, the distribution of surface atmospheric pressure also significantly differed from the characteristic one in the given period of the year. For example, in the third decade of May, the high-pressure region was located in the southern part of the Sea of Okhotsk, above the Kuril Basin (Figure 5A [7]). Usually this area is located in the eastern part of the sea, and air flows directed to the north are formed above this basin. When the pressure distribution has this structure, the atmospheric circulation typical for the summer monsoon is not formed; in principle, it was weakly expressed, since the pressure gradients were small and cold waters with low salinity moved freely to the south, transporting drifting ice.
Distribution of surface pressure (hPa) over the Sea of Okhotsk in the third decade of may (A) and the second decade of June (B) 2011 [7].
Subsequently, the high-pressure region shifted from the sea to the Pacific Ocean. In particular, in the second decade of June, zonal, northeast-oriented air flows prevailed, which is not typical for the warm season (Figure 5B [7]).
However, it is unlikely that only the peculiarities of the synoptic conditions can explain the significant negative temperature anomalies of the sea surface in the northern part of the Sea of Japan, primarily in the main zone of the Tsushima Current influence, off the west coast of Hokkaido Island (up to 5–6°C). Another zone with approximately the same negative anomalies was noted in the zone of the influence of the Amur River runoff in the region of its mouth, in the western part of the Amur Estuary, and in a significant part of the Sakhalin Gulf, as well as on the northeastern shelf of Sakhalin Island (up to about 52° N). Pronounced negative anomalies were observed both on the southwestern and southeastern coasts of Sakhalin Island, as well as in the Aniva Gulf. It is difficult to explain the cause of such a heat deficit in the surface waters of a very wide basin: one of them could be a decrease in the intensity of the Tsushima Current, whose quasi-periodic fluctuations (a cycle with a period of 5–6 years is especially distinguished) have a significant influence on the climate of the Sakhalin-Kuril region [8]. It is also difficult to assess how often such situations can be observed which have led to a delay in the release of juveniles from Sakhalin SFHs lasting from 3 weeks to a month. Probably, due to the low temperature of coastal waters observed for a long time, there could be a mass death of juveniles of natural origin which rolled along the spawning rivers of the island.
When analyzing long-term data series, a question arises – are there unidirectional tendencies of one or another parameter in the specified period of time? This is especially important in the context of global warming, the most noticeable results of which are an increase in winter air temperature in the Arctic latitudes and a decrease in ice cover (area of the water area covered with ice) both in the Arctic Ocean and in the Sea of Okhotsk.
In order to answer this question, in each spatial cell of the 1000 × 1022 matrix, covering the investigated water area (42–60°N and 135–163°E), the linear trend coefficients were calculated using the least squares method, meaning the temperature increase over the year … The calculation was carried out on a 20-year series of data for each month separately, for annual averages, as well as for average temperatures for the season. The seasons for the calculations are shifted by a month relative to the calendar ones due to the specifics of the region: January–March (winter), April–June (spring), July–September (summer) and October–December (autumn).
The linear trend coefficients calculated from the full annual series in the study region are mostly negative, and there are no regions with positive values in the Sea of Okhotsk (Figure 6 [9]). Significant cooling of the surface layer (about 1.5°C over 10 years) was observed in the northern and western parts of the sea; most clearly this process is manifested in the northern part of the sea at some distance from the coast. A less pronounced decrease (at a rate of about 0.5°C over 10 years) is observed in the Kuril Islands and in the band along the western coast of Kamchatka beyond the shelf zone, as well as in the influence zone of the Amur River outflow (Amur Estuary, Sakhalin Bay, northern shelf of Sakhalin Island).
Distribution of linear trend coefficients by number of average annual (above) and average seasonal values. The scale corresponds to degrees celsius over 10 years [9].
A significant decrease (more than 0.5°C over 10 years) was found in the northern part of the Strait of Tatary; further southward, the cooling rate of surface waters decreases and, south of 45° S, a slight increase in the temperature of the surface waters in the Sea of Japan was recorded. The warming process is more pronounced in the northwestern part of the Pacific Ocean, i.e., in the southeastern part of the study region.
Let us now consider the results of calculating the parameters of the linear trend in different seasons. In winter, there is not enough data for a reliable calculation in the northwestern part of the sea (the “Sea of Okhotsk fridge”), on the northern shelf of the sea, and on the northeastern shelf of Sakhalin. In many regions of the basin, where the ice cover is significantly influenced, the calculation is not reliable enough; nevertheless, some ideas of the trends in the thermal regime during the cold period can be put forward.
In the entire Sea of Okhotsk, especially in the northern and western parts of the sea, as well as in the Strait of Tatary of the Sea of Japan and in the regions of the Pacific Ocean adjacent to the Kuril Islands, there is a tendency for the temperature decrease in the surface layer. Signs of the opposite trend are recorded only in the southeastern part of the study region, in the Pacific Ocean, in the northern part of the Sea of Japan, and in the very southern part of the Strait of Tatary (south of 47° N).
The most pronounced decrease in the surface layer temperature is in the springtime. It covers the entire study region, including the northwestern part of the Pacific Ocean, and it is particularly significant in the northern and western parts of the Sea of Okhotsk (the rates of temperature decrease range from 1.0 to 1.5°C over 10 years and even higher in some regions).
The cooling of the surface layer in spring is the most evident consequence of a decrease in ice cover, since in the absence of the ice cover the cooling processes cover a layer of water thicker than in the presence of the ice cover. Undoubtedly, this has a significant impact on the climate of the region and, above all, on the weather conditions of Sakhalin, which are the most affected by this process.
While calculating the trends in sea surface temperature in individual months, it was found that the most intense cooling is observed in the month of May, especially in the northwestern part of the Sea of Okhotsk and along the entire eastern coast of Sakhalin Island from Cape Elizabeth in the north to Cape Aniva in the south. Exceptions are the western part of the Amur Estuary, which accounts for the bulk of the Amur flood, and the basin adjacent to Tauiskaya Bay. It is obvious that the hydrological regime of coastal areas experiencing the influence of the river outflow differs from that typical for the Sea of Okhotsk as a whole.
In summertime, the region is dominated by an increase in the sea surface temperature most pronounced in the northwestern part of the Pacific Ocean. In the Sea of Okhotsk, it is noted in its northwestern part, in the region of the Shantar Islands, in Sakhalin Bay, and in the Amur Estuary, to the east of the northern tip of Sakhalin Island, at the northwestern coast of the Kamchatka Peninsula, and near the Urup and Simushir islands.
In the northern part of the sea, near the Kuril Islands, on the southeastern coast of Sakhalin Island and along the Primorye coast in the Sea of Japan, there is a trend towards a decrease in temperature, although it is more moderate than in springtime. Moreover, in July, the tendency towards a decrease in the sea surface temperature still prevails in the study region; the trend changes only in the northwestern part of the Pacific Ocean. In August, in these regions, warming reaches the highest rates (about 1.5°C over 10 years); the temperature increase was noted in the central part of the Sea of Okhotsk, along the western coast of Kamchatka and off the southeastern coast of Sakhalin, in the Strait of Tatary and the Amur Estuary. In the northern part of the sea, on the northeastern shelf of Sakhalin, and in the Kuril region, the trend towards a decrease in sea water temperature continues.
In September, on the contrary, the intensity of warming in the Pacific Ocean decreases; the greatest warming rate was noted in the northern and northwestern parts of the sea (especially in the shelf zone between Ayan and Okhotsk settlements).
A diffuse pattern is observed in the fall. Relatively small negative trends prevail in the greater part of the Sea of Okhotsk; positive trends (also insignificant) are noted in the eastern part of the sea on the western shelf of Kamchatka and in a relatively narrow band along the northern coast. Smaller areas were also found in the Shantar Islands and Kashevarov Banks and in the southwestern part of the analyzed basin of the Sea of Japan.
The highest rates of the temperature decrease in the surface layer are observed in the Strait of Tatary, in its northern part, and along the western coast of Sakhalin, as well as in the Sea of Okhotsk, in the northern part of it, beyond the shelf, off the southeastern coast of Sakhalin, and also in the band between 145° and 150° E from the Urup and Iturup islands to the Kashevarov Banks.
It was found in the calculations for individual months that a positive trend prevailed in October, and the trend reversed in November and December.
In the work [10], it was found that, in the Sea of Okhotsk and in the region of the Kuril Islands, negative trends were also noted in the spring months; the largest positive trends were recorded in October. Similarity results become very interesting if we take into account the differences in the studied time periods and spatial characteristics of the regions in which the trends were calculated. In the Sea of Japan, no negative trends were identified in this work.
As a result of the analysis of data on the surface temperature of the Sea of Okhotsk over a 20-year period (1998–2017), it was found that the global climate change in this basin caused a decrease in the ice cover and a decrease in the temperature of the upper water layer during the winter–spring period. The negative trends in temperature in the spring in the northern and western parts of the study region, as well as in the Strait of Tatary of the Sea of Japan (from 0.5° to 1.5°C over 10 years), are especially large. This effect in the reduction of the ice cover, both in time and in space, is the most evident and can be explained by an increase in the depth of winter convection. The predominance of a decrease in sea surface temperature, although less pronounced, was also noted in winter and autumn, and generally throughout the year.
In summer, the region is dominated by an increase in sea surface temperature, most pronounced in the northwestern part of the Pacific Ocean. In the Sea of Okhotsk, it was noted in its northwestern part, east of the northern tip of Sakhalin Island, off the northwestern coast of the Kamchatka Peninsula, as well as in some other regions. Moreover, in July, the main role belongs to the processes of cooling of the surface layer; the change in the trend occurs in August and continues in September–October.
These processes play a significant role in the climate variations in the Sea of Okhotsk; in particular, a decrease in the temperature of sea water is noted in the coastal waters of Sakhalin Island. In addition to the weather conditions, the results are important for studying the habitat conditions of commercial fish species and invertebrates in the basin, which is of great fishery importance.
If you look closely at the graph of the course of the mean monthly SST (Figure 7 [11]), then in addition to seasonal fluctuations, you can notice interannual variations. They are especially pronounced in August, when the mean monthly water temperature reaches its maximum value, and are expressed in the modulation of the annual harmonic. Moreover, these oscillations are of a quasiperiodic nature, most likely associated with certain phenomena in the atmosphere and hydrosphere.
Annual variation of average monthly temperature (left) and average temperature in august (right) [11].
Any periodic oscillations can be described by knowing their amplitude, phase and period. Using the least squares method, you can find the corresponding amplitude and phase for each selected period. Thus, it is possible to establish a kind of “influence zones” of harmonics with a certain period, i.e. areas in which the amplitude of one or another harmonic exceeds a certain threshold value. And in order not to interfere in the calculations with long-term components (the period of which exceeds half the length of the series), the trend obtained according to the method described in the previous section was subtracted from the initial data.
The distribution of the amplitudes of temperature fluctuations in the studied region is rather complex. Having determined in each spatial cell the period corresponding to the largest amplitude and displaying the obtained data on the screen, we have established several main periods that play a significant role in interannual SST variations in most cases. For a series of 21 years, it is not entirely correct to calculate fluctuations with a period exceeding 11 years. Short-period fluctuations are unstable and generally have little information. Thus, the spatial distributions of harmonic amplitudes with a period from 3 to 11 years were considered in detail.
In most of the studied water area, the main role was played by variations with a period of about 5.5–6 years (on the graphs for points 2, 5 and 8 in Figure 8, you can see that the largest amplitude at these points corresponds to a period of 66–68 months), the spatial distribution of the amplitude with a period of 6 years is shown in Figure 9 [12]. The zone of its influence is the most extensive and occupies the southern half of the Sea of Okhotsk and the northern part of the Sea of Japan, up to the Amur estuary. The amplitude of this harmonic in the zone of its influence ranges from 1 to 2°C. In the vicinity of the Kuril Islands, off the western coast of about. Hokkaido, off the northeastern coast of about. Sakhalin, the amplitude is slightly lower (from 0.5 to 1°C). Further to the north, starting from 52 N, its influence decreases and practically disappears.
Examples of graphs of the dependence of the amplitude of the harmonic (in °C) from its period (in months). The location of the points is shown in Figure 9 [12].
Distribution of amplitudes (in °C) of interannual fluctuations in the mean monthly sea surface temperature (august) with a certain period (indicated in years in the upper left corner of the image) [12].
In [8], based on the EOF decomposition of the sea surface temperature in the North Pacific Ocean, it was shown that an oscillation with a similar period is characteristic of the entire region influenced by the Kuroshio Current and its branch, the warm Tsushima Current. This is evidenced by the large amplitudes in the zone of the indicated currents and in Figure 9. Consequently, as a result of this study, it was possible to estimate the boundaries of the influence of this component in the Sea of Okhotsk, which runs parallel to the islands of the Kuril ridge and divides this basin into two practically equal parts. The entire northern Sea of Japan is significantly affected by this cycle.
As seen from Figure 8, at most points, one can also note peaks in the range of periods from two to three years. The highest values of the amplitude of the 3-year harmonic can be noted in the northwestern part of the Sea of Okhotsk, at a distance from the coast, as well as near the northwestern coast of Kamchatka and in the strip from 47 to 490 N. and from 147 to 1490 E. in the area of the Kuril deep-water basin and in the northwestern part of the Pacific Ocean. However, the amplitudes of these oscillations are somewhat lower than those of the six-year harmonic (from 1 to 1.5°C). At a distance from these regions, the amplitude gradually decreases to zero.
The spatial distribution of the amplitudes of the cyclic component with a period of 5 years differs markedly from that considered above for a period of 6 years. The zone of its influence is noticeably narrower, it is concentrated mainly on the northern shelf of Hokkaido, in the region of the South Kuril Islands (vast waters both on the Sea of Okhotsk and on the ocean sides), and, surprisingly, on the northeastern shelf of Sakhalin, where the influence of a lower frequency component was not noted. In the Tatar Strait, its role is also noticeable, but expressed to a lesser extent than the 6-year harmonic.
In the western part of the Sea of Okhotsk and the northwestern part of the Pacific Ocean, a cyclical component with a period of about 8 years is significantly manifested. The zone of influence of the Amur river runoff in summer is clearly distinguished in the spatial distribution - the Amur estuary, the southern and eastern parts of the Sakhalin Bay, the area between the Schmidt Peninsula and the Kashevarov Bank [13]. It is interesting that in the area of the Kuroshio Current manifestation, this component has large amplitudes, in the Tsushima Current zone in the Sea of Japan - insignificant, while on the northern shelf of Hokkaido and on the Sea of Okhotsk side of the Southern Kuril Islands, where the warming effect of the Soya Current affects, the amplitudes are significantly.
The lowest frequency of the considered harmonics with a period of 11 years is manifested in the northern part of the Sea of Okhotsk; in other parts of the study area, its role is insignificant. It is rather difficult to put forward a reasonable hypothesis that could explain such significant differences in the very long-term variations in SST in different parts of the same basin. It can only be assumed that due to the comparative shallowness of the northern region, the effect of the winds of the southern rumba and the greater number of sunny days than in the southern part, due to the lesser influence of cloudiness, the influence of the solar cycle is more noticeable here.
Attention is drawn to the fact how the zones of manifestation of harmonics shift with a period of 5 to 11 years. If the zone of influence of the 5-year harmonic is focused near the islands of Sakhalin, Hokkaido and the Southern Kuriles, then with an increase in the period, the region with the highest amplitude shifts clockwise (towards the northeastern coast of Sakhalin and further to the northern part of the Sea of Okhotsk). This interesting fact is also difficult to give a reasonable explanation, it requires additional study.
In work [8], a method was developed for predicting thermal conditions for a year in advance in certain areas of the studied water area (this method was also used to recover data gaps associated with the influence of cloudiness or technical reasons), which consisted in calculating the temperature in a given square in time t according to the formula:
where a and b are the parameters of the linear trend, 𝑐𝑘 are the amplitudes, and 𝜑𝑘 are the phases of the cyclic components (harmonics) of sea surface temperature variations. An essential feature of the method is the fact that the amplitudes and phases of the main cyclical components are calculated by the least squares method, with their periods ranging from 18 to 144 months with a step of 1 month. For each cell, a set of 3–4 harmonics was determined, which make the largest contribution to the interannual variations in SST. Since they are not orthogonal, for forecasting using formula (
Based on the parameters of the obtained cyclic components, a retrospective forecast of thermal conditions for the summer of 2018 was carried out (observational data for 1998–2017 were used to calculate the parameters of harmonics and a linear trend). The calculation was carried out for each spatial cell according to formula (
Examples of temperature forecast graphs (in °C) for the next year. The dashed line shows the prognostic curve. The forecast is carried out for the period from 1998 to 2017. The actual temperature in 2018 is marked with a cross [11].
The curves, which are the sum of the trend and the first four harmonics, generally repeat the actual interannual temperature fluctuations. The correlation coefficient of the initial and predicted series at the selected points exceeds 90%. Note that even the first two harmonics in many cases provide a correlation coefficient of more than 70%. Despite the fact that 2018 was anomalous in terms of thermal conditions (the Tsushima Current and its Okhotsk branch of the Soya Current were weakened, a heat deficit was felt in the zone of influence of the Amur River runoff), and in some other areas, even in such water areas, the forecast can be considered acceptable. An example of a similar situation is given for the Tatar Strait, where the predicted value was higher than the actual one, but the general course was predicted correctly, and the error was not so great. For the northern part of the Sea of Okhotsk, the northeastern shelf of Sakhalin Island, and a number of other areas, good agreement was observed between the calculated and real values of the surface layer temperature.
Let us consider some of the parameters of the graphs below. The standard deviation of the initial and predicted series correspond to each other and range from 1.5°C (Tatar Strait) to 2°C (South Kuriles). The average displacement of the predicted series relative to the initial one ranges from 0.4 to 0.6°C. The forecast error is 1.7°C in the Tatar Strait, 1.3°C near the Southern Kuriles, 0.3–0.4°C in the northern part of the studied water area.
More detailed studies devoted to predictability and the limits of applicability of the approach used will be carried out later. However, we can already say that for a significant part of the Sea of Okhotsk regions and adjacent water areas, the forecast of the surface layer temperature with a one-year lead time is quite successful, although the abnormally cold temperatures that took place in a number of areas in 2018 are rather difficult to predict.
Let us take a closer look at Figure 11. The forecast for August 2017 turned out to be quite successful, the discrepancy between the actual and predicted temperatures in most of the water area does not exceed ±2°C, with a standard deviation of SST of about 1.5-2°C (only in the northwestern part of the Pacific Ocean is the standard SST deviation is within 2-4°C). At the same time, the forecast for August 2018 contains a large area within which the temperature estimate was greatly overestimated (over 4°C). The map of SST anomalies for August 2018 [16] also contains areas of low temperatures (3-4°C lower than the average multiyear norm), which coincide in space with areas of unsuccessful forecast. This area is located in the zone of influence of the Tsushima Current, and the forecast inaccuracies are due to the fact that the weakening of this current occurred two years earlier than the expected date. Indeed, in Figure 8, we see that in the Tatar Strait and the Southern Kuriles, the distance between two neighboring SST minimums decreased to 3–4 years, while its quasiperiodic oscillations with a period of about 6 years are described in the literature [17].
Difference between predicted and actual temperatures [11].
As a result of the analysis of the data set on the surface temperature of the Sea of Okhotsk and adjacent waters, the main cyclical components responsible for the interannual variations of this parameter and the “zones of influence” of each harmonic were determined. It is shown that the main contribution to these variations comes from components with a period of about 6 years, as well as 3, 5, 8, and 11 years.
The zone of influence of the fundamental harmonic is the most extensive and occupies the southern half of the Sea of Okhotsk and the entire northern part of the Sea of Japan; its amplitude is within 1–2°C. In the vicinity of the Kuril Islands, off the western coast of Hokkaido Island, off the northeastern coast of Sakhalin Island, the amplitude is slightly lower (0.5–1°C), and in the northern part of the Sea of Okhotsk its influence is insignificant. Most likely, this component is associated with fluctuations in the Kuroshio Current and its branch, the Tsushima Current [17].
The highest values of the amplitude of the 3-year harmonic (1–1.5°C) can be noted in the northwestern part of the Sea of Okhotsk, at a distance from the coast, as well as off the northwestern coast of Kamchatka, in the region of the Kuril deep-water basin and in the northwestern parts of the Pacific Ocean.
The area of manifestation of the component with a period of 5 years is noticeably narrower, it is concentrated mainly on the northern shelf of Hokkaido, in the region of the South Kuril Islands (both from the Sea of Okhotsk and the ocean side), and on the northeastern shelf of Sakhalin. In the Tatar Strait, its role is also noticeable, but expressed to a lesser extent than the 6-year harmonic.
In the western part of the Sea of Okhotsk, in the zone of influence of the Amur River runoff, as well as in the northwestern part of the Pacific Ocean, a cyclical component with a period of about 8 years is significantly manifested.
The lowest frequency of the considered harmonics with a period of 11 years is manifested in the northern part of the Sea of Okhotsk; in other parts of the study area, its role is insignificant.
Together with the parameters of the linear trend [9], the amplitudes and phases of the main cyclical components (in each spatial cell, 4 harmonics with the highest amplitudes were used) can be used to predict thermal conditions for the next summer. The retrospective calculation for 2018 gave generally satisfactory results, despite the abnormally cold conditions of this year, noted in a number of areas of the studied water area. The possibility of predicting thermal conditions is of practical importance, primarily for assessing the conditions for the approach of Pacific salmon to spawning. And the results obtained show that in some areas of the water area, one can count on a fairly accurate forecast even for such an unstable parameter as the ocean surface temperature.
In general, the success of the forecast is influenced by how pronounced the cyclical components with a certain period in a given area. Identification of the zone of influence of various harmonics allows you to determine the boundaries of the regions in which the applicability of this method can be expected. As for the accuracy of the forecast, one should pay attention to the presence of large areas in which the modulus of the difference between the predicted temperature and the actual one was of the order of two standard deviations. This fact shows that this method does not guarantee the success of the forecast in cases where strong temperature anomalies are observed. It can only be used to obtain a primary estimate of the ocean surface temperature (or another parameter that experiences quasiperiodic oscillations) based on a sufficiently long series. The 21-year series is not enough to estimate low-frequency components (with a period of 30–50 years), which could also affect the quality of the forecast. For a better forecast, you can combine this method with an assessment of the current conditions, adjusting the forecast in the direction of increasing or decreasing temperature, depending on the current meteorological conditions.
This chapter shows how satellite data, going through all levels of processing, become useful products for both science and applied environmental prediction problems. Assessment, and later predicting the dynamics of various environmental parameters, will help reduce damage to nature and identify the degree of influence of anthropogenic factors on the future of the Earth. Based on our analysis results, it seems that the existence of global warming phenomenon has already been proven, but its influence on different parts of the planet is heterogeneous and is not traced in all seasons in the same way. In the spring, there is a tendency to a decrease in the temperature of the surface layer of the Sea of Okhotsk, this tendency continues until August, where it changes to warming condition.
Periodic fluctuations of physical parameters are also not homogeneous in space. It is possible to identify areas where the main oscillation period is 3, 5, 6, 8 and 11 years. Using the sequential spectra method gives a relatively good estimate for the next year’s ocean surface temperature. However, to improve the quality of the forecast, it is necessary to improve the quality of the initial data, comparing data from various sources and filling in the gaps associated with the presence of clouds and ice cover, as well as improve the interpolation algorithms to avoid losing sight of mesoscale phenomena.
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She performed research in perioperative autotransfusion and obtained the degree of PhD in 1993 publishing Peri-operative autotransfusion by means of a blood cell separator.\nBlood transfusion had her special interest being the president of the Haemovigilance Chamber TRIP and performing several tasks in local and national blood bank and anticoagulant-blood transfusion guidelines committees. Currently, she is working as an associate professor and up till recently was the dean at the Albert Schweitzer Hospital Dordrecht. She performed (inter)national tasks as vice-president of the Concilium Anaesthesia and related committees. \nShe performed research in several fields, with over 100 publications in (inter)national journals and numerous papers on scientific conferences. \nShe received several awards and is a member of Honour of the Dutch Society of Anaesthesia.",institutionString:null,institution:{name:"Albert Schweitzer Hospital",country:{name:"Gabon"}}},{id:"83089",title:"Prof.",name:"Aaron",middleName:null,surname:"Ojule",slug:"aaron-ojule",fullName:"Aaron Ojule",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Port Harcourt",country:{name:"Nigeria"}}},{id:"295748",title:"Mr.",name:"Abayomi",middleName:null,surname:"Modupe",slug:"abayomi-modupe",fullName:"Abayomi Modupe",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/no_image.jpg",biography:null,institutionString:null,institution:{name:"Landmark University",country:{name:"Nigeria"}}},{id:"94191",title:"Prof.",name:"Abbas",middleName:null,surname:"Moustafa",slug:"abbas-moustafa",fullName:"Abbas Moustafa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94191/images/96_n.jpg",biography:"Prof. Moustafa got his doctoral degree in earthquake engineering and structural safety from Indian Institute of Science in 2002. He is currently an associate professor at Department of Civil Engineering, Minia University, Egypt and the chairman of Department of Civil Engineering, High Institute of Engineering and Technology, Giza, Egypt. He is also a consultant engineer and head of structural group at Hamza Associates, Giza, Egypt. Dr. Moustafa was a senior research associate at Vanderbilt University and a JSPS fellow at Kyoto and Nagasaki Universities. He has more than 40 research papers published in international journals and conferences. He acts as an editorial board member and a reviewer for several regional and international journals. His research interest includes earthquake engineering, seismic design, nonlinear dynamics, random vibration, structural reliability, structural health monitoring and uncertainty modeling.",institutionString:null,institution:{name:"Minia University",country:{name:"Egypt"}}},{id:"84562",title:"Dr.",name:"Abbyssinia",middleName:null,surname:"Mushunje",slug:"abbyssinia-mushunje",fullName:"Abbyssinia Mushunje",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Fort Hare",country:{name:"South Africa"}}},{id:"202206",title:"Associate Prof.",name:"Abd Elmoniem",middleName:"Ahmed",surname:"Elzain",slug:"abd-elmoniem-elzain",fullName:"Abd Elmoniem Elzain",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Kassala University",country:{name:"Sudan"}}},{id:"98127",title:"Dr.",name:"Abdallah",middleName:null,surname:"Handoura",slug:"abdallah-handoura",fullName:"Abdallah Handoura",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"École Supérieure des Télécommunications",country:{name:"Morocco"}}},{id:"91404",title:"Prof.",name:"Abdecharif",middleName:null,surname:"Boumaza",slug:"abdecharif-boumaza",fullName:"Abdecharif Boumaza",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Abbès Laghrour University of Khenchela",country:{name:"Algeria"}}},{id:"105795",title:"Prof.",name:"Abdel Ghani",middleName:null,surname:"Aissaoui",slug:"abdel-ghani-aissaoui",fullName:"Abdel Ghani Aissaoui",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/105795/images/system/105795.jpeg",biography:"Abdel Ghani AISSAOUI is a Full Professor of electrical engineering at University of Bechar (ALGERIA). He was born in 1969 in Naama, Algeria. He received his BS degree in 1993, the MS degree in 1997, the PhD degree in 2007 from the Electrical Engineering Institute of Djilali Liabes University of Sidi Bel Abbes (ALGERIA). He is an active member of IRECOM (Interaction Réseaux Electriques - COnvertisseurs Machines) Laboratory and IEEE senior member. He is an editor member for many international journals (IJET, RSE, MER, IJECE, etc.), he serves as a reviewer in international journals (IJAC, ECPS, COMPEL, etc.). He serves as member in technical committee (TPC) and reviewer in international conferences (CHUSER 2011, SHUSER 2012, PECON 2012, SAI 2013, SCSE2013, SDM2014, SEB2014, PEMC2014, PEAM2014, SEB (2014, 2015), ICRERA (2015, 2016, 2017, 2018,-2019), etc.). His current research interest includes power electronics, control of electrical machines, artificial intelligence and Renewable energies.",institutionString:"University of Béchar",institution:{name:"University of Béchar",country:{name:"Algeria"}}},{id:"99749",title:"Dr.",name:"Abdel Hafid",middleName:null,surname:"Essadki",slug:"abdel-hafid-essadki",fullName:"Abdel Hafid Essadki",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"École Nationale Supérieure de Technologie",country:{name:"Algeria"}}},{id:"101208",title:"Prof.",name:"Abdel Karim",middleName:"Mohamad",surname:"El Hemaly",slug:"abdel-karim-el-hemaly",fullName:"Abdel Karim El Hemaly",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/101208/images/733_n.jpg",biography:"OBGYN.net Editorial Advisor Urogynecology.\nAbdel Karim M. A. El-Hemaly, MRCOG, FRCS � Egypt.\n \nAbdel Karim M. A. El-Hemaly\nProfessor OB/GYN & Urogynecology\nFaculty of medicine, Al-Azhar University \nPersonal Information: \nMarried with two children\nWife: Professor Laila A. Moussa MD.\nSons: Mohamad A. M. El-Hemaly Jr. MD. Died March 25-2007\nMostafa A. M. El-Hemaly, Computer Scientist working at Microsoft Seatle, USA. \nQualifications: \n1.\tM.B.-Bch Cairo Univ. June 1963. \n2.\tDiploma Ob./Gyn. Cairo Univ. April 1966. \n3.\tDiploma Surgery Cairo Univ. Oct. 1966. \n4.\tMRCOG London Feb. 1975. \n5.\tF.R.C.S. Glasgow June 1976. \n6.\tPopulation Study Johns Hopkins 1981. \n7.\tGyn. Oncology Johns Hopkins 1983. \n8.\tAdvanced Laparoscopic Surgery, with Prof. Paulson, Alexandria, Virginia USA 1993. \nSocieties & Associations: \n1.\t Member of the Royal College of Ob./Gyn. London. \n2.\tFellow of the Royal College of Surgeons Glasgow UK. \n3.\tMember of the advisory board on urogyn. FIGO. \n4.\tMember of the New York Academy of Sciences. \n5.\tMember of the American Association for the Advancement of Science. \n6.\tFeatured in �Who is Who in the World� from the 16th edition to the 20th edition. \n7.\tFeatured in �Who is Who in Science and Engineering� in the 7th edition. \n8.\tMember of the Egyptian Fertility & Sterility Society. \n9.\tMember of the Egyptian Society of Ob./Gyn. \n10.\tMember of the Egyptian Society of Urogyn. \n\nScientific Publications & Communications:\n1- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Asim Kurjak, Ahmad G. Serour, Laila A. S. Mousa, Amr M. Zaied, Khalid Z. El Sheikha. \nImaging the Internal Urethral Sphincter and the Vagina in Normal Women and Women Suffering from Stress Urinary Incontinence and Vaginal Prolapse. Gynaecologia Et Perinatologia, Vol18, No 4; 169-286 October-December 2009.\n2- Abdel Karim M. El Hemaly*, Laila A. S. Mousa Ibrahim M. Kandil, Fatma S. El Sokkary, Ahmad G. Serour, Hossam Hussein.\nFecal Incontinence, A Novel Concept: The Role of the internal Anal sphincter (IAS) in defecation and fecal incontinence. Gynaecologia Et Perinatologia, Vol19, No 2; 79-85 April -June 2010.\n3- Abdel Karim M. El Hemaly*, Laila A. S. Mousa Ibrahim M. Kandil, Fatma S. El Sokkary, Ahmad G. Serour, Hossam Hussein.\nSurgical Treatment of Stress Urinary Incontinence, Fecal Incontinence and Vaginal Prolapse By A Novel Operation \n"Urethro-Ano-Vaginoplasty"\n Gynaecologia Et Perinatologia, Vol19, No 3; 129-188 July-September 2010.\n4- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Laila A. S. Mousa and Mohamad A.K.M.El Hemaly.\nUrethro-vaginoplasty, an innovated operation for the treatment of: Stress Urinary Incontinence (SUI), Detursor Overactivity (DO), Mixed Urinary Incontinence and Anterior Vaginal Wall Descent. \nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/ urethro-vaginoplasty_01\n\n5- Abdel Karim M. El Hemaly, Ibrahim M Kandil, Mohamed M. Radwan.\n Urethro-raphy a new technique for surgical management of Stress Urinary Incontinence.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/\nnew-tech-urethro\n\n6- Abdel Karim M. El Hemaly, Ibrahim M Kandil, Mohamad A. Rizk, Nabil Abdel Maksoud H., Mohamad M. Radwan, Khalid Z. El Shieka, Mohamad A. K. M. El Hemaly, and Ahmad T. El Saban.\nUrethro-raphy The New Operation for the treatment of stress urinary incontinence, SUI, detrusor instability, DI, and mixed-type of urinary incontinence; short and long term results. \nhttp://www.obgyn.net/urogyn/urogyn.asp?page=urogyn/articles/\nurethroraphy-09280\n\n7-Abdel Karim M. El Hemaly, Ibrahim M Kandil, and Bahaa E. El Mohamady. Menopause, and Voiding troubles. \nhttp://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly03/el-hemaly03-ss\n\n8-El Hemaly AKMA, Mousa L.A. Micturition and Urinary\tContinence. Int J Gynecol Obstet 1996; 42: 291-2. \n\n9-Abdel Karim M. El Hemaly.\n Urinary incontinence in gynecology, a review article.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/abs-urinary_incotinence_gyn_ehemaly \n\n10-El Hemaly AKMA. Nocturnal Enuresis: Pathogenesis and Treatment. \nInt Urogynecol J Pelvic Floor Dysfunct 1998;9: 129-31.\n \n11-El Hemaly AKMA, Mousa L.A.E. Stress Urinary Incontinence, a New Concept. Eur J Obstet Gynecol Reprod Biol 1996; 68: 129-35. \n\n12- El Hemaly AKMA, Kandil I. M. Stress Urinary Incontinence SUI facts and fiction. Is SUI a puzzle?! http://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly/el-hemaly-ss\n\n13-Abdel Karim El Hemaly, Nabil Abdel Maksoud, Laila A. Mousa, Ibrahim M. Kandil, Asem Anwar, M.A.K El Hemaly and Bahaa E. El Mohamady. \nEvidence based Facts on the Pathogenesis and Management of SUI. http://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly02/el-hemaly02-ss\n\n14- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Mohamad A. Rizk and Mohamad A.K.M.El Hemaly.\n Urethro-plasty, a Novel Operation based on a New Concept, for the Treatment of Stress Urinary Incontinence, S.U.I., Detrusor Instability, D.I., and Mixed-type of Urinary Incontinence.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/urethro-plasty_01\n\n15-Ibrahim M. Kandil, Abdel Karim M. El Hemaly, Mohamad M. Radwan: Ultrasonic Assessment of the Internal Urethral Sphincter in Stress Urinary Incontinence. The Internet Journal of Gynecology and Obstetrics. 2003. Volume 2 Number 1. \n\n\n16-Abdel Karim M. El Hemaly. Nocturnal Enureses: A Novel Concept on its pathogenesis and Treatment.\nhttp://www.obgyn.net/urogynecolgy/?page=articles/nocturnal_enuresis\n\n17- Abdel Karim M. El Hemaly. Nocturnal Enureses: An Update on the pathogenesis and Treatment.\nhttp://www.obgyn.net/urogynecology/?page=/ENHLIDH/PUBD/FEATURES/\nPresentations/ Nocturnal_Enuresis/nocturnal_enuresis\n\n18-Maternal Mortality in Egypt, a cry for help and attention. The Second International Conference of the African Society of Organization & Gestosis, 1998, 3rd Annual International Conference of Ob/Gyn Department � Sohag Faculty of Medicine University. Feb. 11-13. Luxor, Egypt. \n19-Postmenopausal Osteprosis. The 2nd annual conference of Health Insurance Organization on Family Planning and its role in primary health care. Zagaziz, Egypt, February 26-27, 1997, Center of Complementary Services for Maternity and childhood care. \n20-Laparoscopic Assisted vaginal hysterectomy. 10th International Annual Congress Modern Trends in Reproductive Techniques 23-24 March 1995. Alexandria, Egypt. \n21-Immunological Studies in Pre-eclamptic Toxaemia. Proceedings of 10th Annual Ain Shams Medical Congress. Cairo, Egypt, March 6-10, 1987. \n22-Socio-demographic factorse affecting acceptability of the long-acting contraceptive injections in a rural Egyptian community. Journal of Biosocial Science 29:305, 1987. \n23-Plasma fibronectin levels hypertension during pregnancy. The Journal of the Egypt. Soc. of Ob./Gyn. 13:1, 17-21, Jan. 1987. \n24-Effect of smoking on pregnancy. Journal of Egypt. Soc. of Ob./Gyn. 12:3, 111-121, Sept 1986. \n25-Socio-demographic aspects of nausea and vomiting in early pregnancy. Journal of the Egypt. Soc. of Ob./Gyn. 12:3, 35-42, Sept. 1986. \n26-Effect of intrapartum oxygen inhalation on maternofetal blood gases and pH. Journal of the Egypt. Soc. of Ob./Gyn. 12:3, 57-64, Sept. 1986. \n27-The effect of severe pre-eclampsia on serum transaminases. The Egypt. J. Med. Sci. 7(2): 479-485, 1986. \n28-A study of placental immunoreceptors in pre-eclampsia. The Egypt. J. Med. Sci. 7(2): 211-216, 1986. \n29-Serum human placental lactogen (hpl) in normal, toxaemic and diabetic pregnant women, during pregnancy and its relation to the outcome of pregnancy. Journal of the Egypt. Soc. of Ob./Gyn. 12:2, 11-23, May 1986. \n30-Pregnancy specific B1 Glycoprotein and free estriol in the serum of normal, toxaemic and diabetic pregnant women during pregnancy and after delivery. Journal of the Egypt. Soc. of Ob./Gyn. 12:1, 63-70, Jan. 1986. Also was accepted and presented at Xith World Congress of Gynecology and Obstetrics, Berlin (West), September 15-20, 1985. \n31-Pregnancy and labor in women over the age of forty years. Accepted and presented at Al-Azhar International Medical Conference, Cairo 28-31 Dec. 1985. \n32-Effect of Copper T intra-uterine device on cervico-vaginal flora. Int. J. Gynaecol. Obstet. 23:2, 153-156, April 1985. \n33-Factors affecting the occurrence of post-Caesarean section febrile morbidity. Population Sciences, 6, 139-149, 1985. \n34-Pre-eclamptic toxaemia and its relation to H.L.A. system. Population Sciences, 6, 131-139, 1985. \n35-The menstrual pattern and occurrence of pregnancy one year after discontinuation of Depo-medroxy progesterone acetate as a postpartum contraceptive. Population Sciences, 6, 105-111, 1985. \n36-The menstrual pattern and side effects of Depo-medroxy progesterone acetate as postpartum contraceptive. Population Sciences, 6, 97-105, 1985. \n37-Actinomyces in the vaginas of women with and without intrauterine contraceptive devices. Population Sciences, 6, 77-85, 1985. \n38-Comparative efficacy of ibuprofen and etamsylate in the treatment of I.U.D. menorrhagia. Population Sciences, 6, 63-77, 1985. \n39-Changes in cervical mucus copper and zinc in women using I.U.D.�s. Population Sciences, 6, 35-41, 1985. \n40-Histochemical study of the endometrium of infertile women. Egypt. J. Histol. 8(1) 63-66, 1985. \n41-Genital flora in pre- and post-menopausal women. Egypt. J. Med. Sci. 4(2), 165-172, 1983. \n42-Evaluation of the vaginal rugae and thickness in 8 different groups. Journal of the Egypt. Soc. of Ob./Gyn. 9:2, 101-114, May 1983. \n43-The effect of menopausal status and conjugated oestrogen therapy on serum cholesterol, triglycerides and electrophoretic lipoprotein patterns. Al-Azhar Medical Journal, 12:2, 113-119, April 1983. \n44-Laparoscopic ventrosuspension: A New Technique. Int. J. Gynaecol. Obstet., 20, 129-31, 1982. \n45-The laparoscope: A useful diagnostic tool in general surgery. Al-Azhar Medical Journal, 11:4, 397-401, Oct. 1982. \n46-The value of the laparoscope in the diagnosis of polycystic ovary. Al-Azhar Medical Journal, 11:2, 153-159, April 1982. \n47-An anaesthetic approach to the management of eclampsia. Ain Shams Medical Journal, accepted for publication 1981. \n48-Laparoscopy on patients with previous lower abdominal surgery. Fertility management edited by E. Osman and M. Wahba 1981. \n49-Heart diseases with pregnancy. Population Sciences, 11, 121-130, 1981. \n50-A study of the biosocial factors affecting perinatal mortality in an Egyptian maternity hospital. Population Sciences, 6, 71-90, 1981. \n51-Pregnancy Wastage. Journal of the Egypt. Soc. of Ob./Gyn. 11:3, 57-67, Sept. 1980. \n52-Analysis of maternal deaths in Egyptian maternity hospitals. Population Sciences, 1, 59-65, 1979. \nArticles published on OBGYN.net: \n1- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Laila A. S. Mousa and Mohamad A.K.M.El Hemaly.\nUrethro-vaginoplasty, an innovated operation for the treatment of: Stress Urinary Incontinence (SUI), Detursor Overactivity (DO), Mixed Urinary Incontinence and Anterior Vaginal Wall Descent. \nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/ urethro-vaginoplasty_01\n\n2- Abdel Karim M. El Hemaly, Ibrahim M Kandil, Mohamed M. Radwan.\n Urethro-raphy a new technique for surgical management of Stress Urinary Incontinence.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/\nnew-tech-urethro\n\n3- Abdel Karim M. El Hemaly, Ibrahim M Kandil, Mohamad A. Rizk, Nabil Abdel Maksoud H., Mohamad M. Radwan, Khalid Z. El Shieka, Mohamad A. K. M. El Hemaly, and Ahmad T. El Saban.\nUrethro-raphy The New Operation for the treatment of stress urinary incontinence, SUI, detrusor instability, DI, and mixed-type of urinary incontinence; short and long term results. \nhttp://www.obgyn.net/urogyn/urogyn.asp?page=urogyn/articles/\nurethroraphy-09280\n\n4-Abdel Karim M. El Hemaly, Ibrahim M Kandil, and Bahaa E. El Mohamady. Menopause, and Voiding troubles. \nhttp://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly03/el-hemaly03-ss\n\n5-El Hemaly AKMA, Mousa L.A. Micturition and Urinary\tContinence. Int J Gynecol Obstet 1996; 42: 291-2. \n\n6-Abdel Karim M. El Hemaly.\n Urinary incontinence in gynecology, a review article.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/abs-urinary_incotinence_gyn_ehemaly \n\n7-El Hemaly AKMA. Nocturnal Enuresis: Pathogenesis and Treatment. \nInt Urogynecol J Pelvic Floor Dysfunct 1998;9: 129-31.\n \n8-El Hemaly AKMA, Mousa L.A.E. Stress Urinary Incontinence, a New Concept. Eur J Obstet Gynecol Reprod Biol 1996; 68: 129-35. \n\n9- El Hemaly AKMA, Kandil I. M. Stress Urinary Incontinence SUI facts and fiction. Is SUI a puzzle?! http://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly/el-hemaly-ss\n\n10-Abdel Karim El Hemaly, Nabil Abdel Maksoud, Laila A. Mousa, Ibrahim M. Kandil, Asem Anwar, M.A.K El Hemaly and Bahaa E. El Mohamady. \nEvidence based Facts on the Pathogenesis and Management of SUI. http://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly02/el-hemaly02-ss\n\n11- Abdel Karim M. El Hemaly*, Ibrahim M. 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