Dr. Pletser’s experience includes 30 years of working with the European Space Agency as a Senior Physicist/Engineer and coordinating their parabolic flight campaigns, and he is the Guinness World Record holder for the most number of aircraft flown (12) in parabolas, personally logging more than 7,300 parabolas.
\\n\\n
Seeing the 5,000th book published makes us at the same time proud, happy, humble, and grateful. This is a great opportunity to stop and celebrate what we have done so far, but is also an opportunity to engage even more, grow, and succeed. It wouldn't be possible to get here without the synergy of team members’ hard work and authors and editors who devote time and their expertise into Open Access book publishing with us.
\\n\\n
Over these years, we have gone from pioneering the scientific Open Access book publishing field to being the world’s largest Open Access book publisher. Nonetheless, our vision has remained the same: to meet the challenges of making relevant knowledge available to the worldwide community under the Open Access model.
\\n\\n
We are excited about the present, and we look forward to sharing many more successes in the future.
\\n\\n
Thank you all for being part of the journey. 5,000 times thank you!
\\n\\n
Now with 5,000 titles available Open Access, which one will you read next?
Preparation of Space Experiments edited by international leading expert Dr. Vladimir Pletser, Director of Space Training Operations at Blue Abyss is the 5,000th Open Access book published by IntechOpen and our milestone publication!
\n\n
"This book presents some of the current trends in space microgravity research. The eleven chapters introduce various facets of space research in physical sciences, human physiology and technology developed using the microgravity environment not only to improve our fundamental understanding in these domains but also to adapt this new knowledge for application on earth." says the editor. Listen what else Dr. Pletser has to say...
\n\n\n\n
Dr. Pletser’s experience includes 30 years of working with the European Space Agency as a Senior Physicist/Engineer and coordinating their parabolic flight campaigns, and he is the Guinness World Record holder for the most number of aircraft flown (12) in parabolas, personally logging more than 7,300 parabolas.
\n\n
Seeing the 5,000th book published makes us at the same time proud, happy, humble, and grateful. This is a great opportunity to stop and celebrate what we have done so far, but is also an opportunity to engage even more, grow, and succeed. It wouldn't be possible to get here without the synergy of team members’ hard work and authors and editors who devote time and their expertise into Open Access book publishing with us.
\n\n
Over these years, we have gone from pioneering the scientific Open Access book publishing field to being the world’s largest Open Access book publisher. Nonetheless, our vision has remained the same: to meet the challenges of making relevant knowledge available to the worldwide community under the Open Access model.
\n\n
We are excited about the present, and we look forward to sharing many more successes in the future.
\n\n
Thank you all for being part of the journey. 5,000 times thank you!
\n\n
Now with 5,000 titles available Open Access, which one will you read next?
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"5419",leadTitle:null,fullTitle:"Virtual Learning",title:"Virtual Learning",subtitle:null,reviewType:"peer-reviewed",abstract:"The first chapter provides an overview of the popular systems for distance learning. In the second chapter, a review of all major social and economic activities in order to improve the system of virtual learning is given. The third chapter deals with the influence of technology in the management of educational institutions. The fourth chapter provides an overview of the graphic communication. The fifth chapter confirms that quality assurance remains an integral and indispensable part of the process of virtual learning. The sixth and seventh chapters are dedicated to health and mutual communication about health problems and causes. The eighth and ninth chapters are dedicated to massive open online courses (MOOC). The tenth chapter refers to the widespread use of virtual reality in industrial environments.",isbn:"978-953-51-2823-6",printIsbn:"978-953-51-2824-3",pdfIsbn:"978-953-51-4136-5",doi:"10.5772/62799",price:119,priceEur:129,priceUsd:155,slug:"virtual-learning",numberOfPages:184,isOpenForSubmission:!1,isInWos:1,isInBkci:!0,hash:"5ec59dce356b02297b7dc3bd56eec0df",bookSignature:"Dragan Cvetkovic",publishedDate:"December 14th 2016",coverURL:"https://cdn.intechopen.com/books/images_new/5419.jpg",numberOfDownloads:21780,numberOfWosCitations:23,numberOfCrossrefCitations:19,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:29,numberOfDimensionsCitationsByBook:0,hasAltmetrics:1,numberOfTotalCitations:71,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 31st 2016",dateEndSecondStepPublish:"April 21st 2016",dateEndThirdStepPublish:"July 26th 2016",dateEndFourthStepPublish:"October 24th 2016",dateEndFifthStepPublish:"November 23rd 2016",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,8",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković",profilePictureURL:"https://mts.intechopen.com/storage/users/101330/images/system/101330.jpg",biography:"Dragan Cvetković obtained a Ph.D. in Aeronautics from the\nFaculty of Mechanical Engineering, University of Belgrade, in\n1997. To date, he has published sixty-five books, scripts, and\npracticums about computers and computer programs, aviation\nweapons, and flight mechanics. He has published many scientific\npapers as well. Dr. Cvetković became a full professor of Informatics and Computing at Singidunum University, Belgrade, in\n2014. Since 2019, he has been the vice-rector for teaching at the same university",institutionString:"Singidunum University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"4",totalChapterViews:"0",totalEditedBooks:"9",institution:{name:"Singidunum University",institutionURL:null,country:{name:"Serbia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1315",title:"Distance Education",slug:"distance-education"}],chapters:[{id:"52577",title:"A Review of Distance Learning and Learning Management Systems",doi:"10.5772/65222",slug:"a-review-of-distance-learning-and-learning-management-systems",totalDownloads:3034,totalCrossrefCites:7,totalDimensionsCites:13,hasAltmetrics:1,abstract:"In recent years, rapid developments in technology and the web have led to many changes in education. One of the most important changes in education is in the form of distance learning. Distance learning, which is used to define education where educators and learners are physically separated, is not a new concept; however, emerging technologies and the web allow web‐based distance learning and therefore increase its popularity. As a result of these developments, many universities have started to use web‐based distance learning systems to provide flexible education that is independent of time and place. In this chapter, we review all popular, widely used, and well‐known learning management systems and include detailed comparison of some of these systems to allow institutions to choose the right system for their distance education activities.",signatures:"Mümine Kaya Keleş and Selma Ayşe Özel",downloadPdfUrl:"/chapter/pdf-download/52577",previewPdfUrl:"/chapter/pdf-preview/52577",authors:[{id:"190444",title:"Dr.",name:"Mümine",surname:"Kaya Keleş",slug:"mumine-kaya-keles",fullName:"Mümine Kaya Keleş"},{id:"190656",title:"Associate Prof.",name:"Selma Ayşe",surname:"Özel",slug:"selma-ayse-ozel",fullName:"Selma Ayşe Özel"}],corrections:null},{id:"52213",title:"Social Collaboration Style Preferences and Cognitive Receptivity to Technological Change and Innovation in Open and Distance e-Learning",doi:"10.5772/65220",slug:"social-collaboration-style-preferences-and-cognitive-receptivity-to-technological-change-and-innovat",totalDownloads:1573,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The proliferation of online courses in open and distance e-learning higher education contexts brought attention to the role of social collaboration activities in enhancing student learning. Constructive social collaboration in an e-learning environment is influenced by the interaction dynamics of the relevant virtual learning community. Social learning involves the acquisition of knowledge and skills relevant to the individual’s unique work or learning context through collaborative endeavours and interactions that often include the use of technological tools such as web-based platforms and social media technological applications. This chapter focuses on how the social collaboration style preferences of members of the virtual learning community relate to their cognitive receptivity to technological change and innovation. The practical implications for virtual learning in open and distance e-learning contexts are outlined.",signatures:"Melinde Coetzee",downloadPdfUrl:"/chapter/pdf-download/52213",previewPdfUrl:"/chapter/pdf-preview/52213",authors:[{id:"188011",title:"Prof.",name:"Melinde",surname:"Coetzee",slug:"melinde-coetzee",fullName:"Melinde Coetzee"}],corrections:null},{id:"52243",title:"Digital Transformation in School Management and Culture",doi:"10.5772/65221",slug:"digital-transformation-in-school-management-and-culture",totalDownloads:1909,totalCrossrefCites:3,totalDimensionsCites:4,hasAltmetrics:0,abstract:"Quality becomes milestone for enhancing learning and teaching practices through contemporary standards. In this respect, considering the outcomes of transformation is essential. School management is an umbrella of facilitating learning and teaching. Therefore, role of digital transformation in school management is an intensified need to be underlined. In establishing school culture, school management plays an essential role that digital transformation effects the school management and culture for the quality in education. The nature of this research is qualitative. Reflective reports of headmasters are gathered as data to understand the readability and awareness of school management to the digital transformation in the case of North Cyprus. In addition, content analysis is done to realize the upcoming issues in school management and digital transformation. As this focus is demanding for developing countries especially North Cyprus, this research revealed that headmasters have awareness on the use of digital and technological facilities. They are aware on digital transformation although budget and application restrictions are revealed to apply this transformation.",signatures:"Fahriye Altınay, Gokmen Dagli and Zehra Altınay",downloadPdfUrl:"/chapter/pdf-download/52243",previewPdfUrl:"/chapter/pdf-preview/52243",authors:[{id:"189778",title:"Dr.",name:"Fahriye",surname:"Altınay",slug:"fahriye-altinay",fullName:"Fahriye Altınay"},{id:"189780",title:"Dr.",name:"Gokmen",surname:"Dagli",slug:"gokmen-dagli",fullName:"Gokmen Dagli"},{id:"189781",title:"Dr.",name:"Zehra",surname:"Altınay",slug:"zehra-altinay",fullName:"Zehra Altınay"}],corrections:null},{id:"53091",title:"Usage of 3D Computer Modelling in Learning Engineering Graphics",doi:"10.5772/65217",slug:"usage-of-3d-computer-modelling-in-learning-engineering-graphics",totalDownloads:1972,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"What is graphic communication? Firstly, it is a very effective way of communication between the technical idea and the final solution of the problem in engineering. The process engineering design (design) begins with visualization, i.e., reviewing the problem and possible solutions. Then, sketching leads to the preparation of the initial idea. Next step is preparation of geometric models, which are used for a variety of engineering analysis and, finally, creating detailed drawings and/or 3D models, which are used for the production process. Visualization, sketching, modelling and preparation of technical documentation are ways in which engineers and technologists communicate in creating new products and structures in the modern technical world. Essentially, graphic communication, which is done via engineering drawings and models, is the clean, practical language with defined rules that need to be overcome if one wants to be successful in engineering design (any kind of design). When that language can overcome any approach to solving engineering problems. Ninety‐two percent of the engineering design process is based on the graphic display. The remaining 8% is divided between the mathematical calculations and written and oral communication. Fifty percent of the projecting time a designer spends on are purely visual and graphic activities. We like precision in communication. Engineers use graphical tools, some of which are centuries old and are used day‐to‐day, while others are very new and conditioned by the rapid development of computer technology, such as Computer Aided Design (CAD) systems. From this chapter, users will be able to familiarize themselves with the above tools and principles of their use.",signatures:"Zorana Jeli, Branislav Popokonstantinovic and Misa Stojicevic",downloadPdfUrl:"/chapter/pdf-download/53091",previewPdfUrl:"/chapter/pdf-preview/53091",authors:[{id:"189704",title:"Associate Prof.",name:"Zorana",surname:"Jeli",slug:"zorana-jeli",fullName:"Zorana Jeli"},{id:"194655",title:"Prof.",name:"Branislav",surname:"Popkonstantinovic",slug:"branislav-popkonstantinovic",fullName:"Branislav Popkonstantinovic"}],corrections:null},{id:"53292",title:"Quality Assurance in Virtual Learning Environments for Open Distance Learning",doi:"10.5772/65746",slug:"quality-assurance-in-virtual-learning-environments-for-open-distance-learning",totalDownloads:1939,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:1,abstract:"Quality assurance, as the fundamental pillar of higher education development, continues to remain an integral part of the e‐learning process. Most importantly, it influences reforms in higher education institutions globally. This chapter departs on the assumptions that (1) quality assurance, as power relations construct, is not free from cultural hegemony and (2) quality assurance in virtual learning environments should be guided and informed by Paulo Freire's humanizing pedagogy. In this chapter, we shall argue that quality assurance is both a philosophical problem and a policy imperative that is critical for the internationalization and globalization of higher education, more specifically virtual learning environments. We will further argue that the emphasis placed on the importance of quality assurance in virtual learning practices has been blind‐spotted by the fact that quality assurance can be viewed as agent of cultural hegemony and cultural reproduction of capitalist societies. While we agree with all the positive elements attributed to quality assurance in virtual learning, we argue that they should be characterized by humanizing pedagogy and the international dimension (exchange of knowledge and interactive networking) and cultural hybridity.",signatures:"Victor J. Pitsoe and Matsephe M. Letseka",downloadPdfUrl:"/chapter/pdf-download/53292",previewPdfUrl:"/chapter/pdf-preview/53292",authors:[{id:"187812",title:"Prof.",name:"Victor",surname:"Pitsoe",slug:"victor-pitsoe",fullName:"Victor Pitsoe"},{id:"195883",title:"Dr.",name:"Matsephe M.",surname:"Letseka",slug:"matsephe-m.-letseka",fullName:"Matsephe M. Letseka"}],corrections:null},{id:"52988",title:"‘Women on a Wiki’: Social Constructivist Analysis of the Effectiveness of Online Collaborative Spaces for Reflective Learning in Women‘s Health Studies",doi:"10.5772/65298",slug:"-women-on-a-wiki-social-constructivist-analysis-of-the-effectiveness-of-online-collaborative-spaces-",totalDownloads:1649,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"Public health undergraduate students studying the unit Women's Health undertook a teaching and learning exercise which required them to learn to create and use a wiki website for reflective learning purposes. A wiki is a group of web pages that allows users to add content, similar to a discussion forum or blog, while permitting others to edit and provide feedback. The Women's Health wiki provided an online shared, collaborative and creative space wherein the students’ perceptions of women's health issues could be discussed, reflected upon and debated. This chapter develops a social constructivist theoretical framework for analysing the content developed on the Women's Health wiki by the students and provides a theoretical model for how the wiki worked to aid reflective and critical thinking, as well as developing technological and communicative skills among students, and discusses implications for their future use in a tertiary setting.",signatures:"Julie‐Anne Carroll, Mangalam Sankupellay, Michelle Cornford and\nNajmah Bahir",downloadPdfUrl:"/chapter/pdf-download/52988",previewPdfUrl:"/chapter/pdf-preview/52988",authors:[{id:"194108",title:"Dr.",name:"Julie-Ann",surname:"Carroll",slug:"julie-ann-carroll",fullName:"Julie-Ann Carroll"},{id:"194803",title:"Ms.",name:"Michelle",surname:"Cornford",slug:"michelle-cornford",fullName:"Michelle Cornford"},{id:"194804",title:"Ms.",name:"Najmah",surname:"Bahir",slug:"najmah-bahir",fullName:"Najmah Bahir"},{id:"194805",title:"Dr.",name:"Mangalam",surname:"Sankupellay",slug:"mangalam-sankupellay",fullName:"Mangalam Sankupellay"}],corrections:null},{id:"52297",title:"New Educational Challenges and Innovations: Students with Disability in Immersive Learning Environments",doi:"10.5772/65219",slug:"new-educational-challenges-and-innovations-students-with-disability-in-immersive-learning-environmen",totalDownloads:2083,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"In today society, one of the most demanded challenges faced by the current educational system is the educational response to diversity in the various educational contexts. University lecturers are opening new lines of research focused on issues as social demand and current reality of produced new learning environments. The general aim of this study was to design learning environments using immersive virtual reality and evaluate improvements produced by this tool in relation to the difficulties show by the participants. From that point, an action plan was created to recreate school situations with a high degree of realism and interaction using IVRSystem. In this way, we want to obtain answers according to the dysfunctions of educational system to work with these students. This was done by a mixed design. On the one hand, a quasi-experimental methodology was used with a control group and an experimental group. On the other hand, direct and observation and applicative methodology made possible the development of educational intervention in immersive learning environments. The results obtained throughout these years have given a response to the initial problem-question raised: Can immersive virtual learning environments serve as a support tool for working disabilities of students, which have a visual learning style, such as students with autism spectrum disorders?",signatures:"Gonzalo Lorenzo, Asunción Lledó, Rosabel Roig, Alejandro Lorenzo\nand Jorge Pomares",downloadPdfUrl:"/chapter/pdf-download/52297",previewPdfUrl:"/chapter/pdf-preview/52297",authors:[{id:"5683",title:"Dr.",name:"Jorge",surname:"Pomares",slug:"jorge-pomares",fullName:"Jorge Pomares"},{id:"187920",title:"Prof.",name:"Gonzalo",surname:"Lorenzo",slug:"gonzalo-lorenzo",fullName:"Gonzalo Lorenzo"},{id:"189580",title:"Prof.",name:"Asunción",surname:"Lledó",slug:"asuncion-lledo",fullName:"Asunción Lledó"},{id:"189581",title:"Prof.",name:"Rosabel",surname:"Roig",slug:"rosabel-roig",fullName:"Rosabel Roig"}],corrections:null},{id:"53197",title:"MOOCs in Higher Education",doi:"10.5772/66137",slug:"moocs-in-higher-education",totalDownloads:3321,totalCrossrefCites:7,totalDimensionsCites:7,hasAltmetrics:0,abstract:"MOOCs have been the major issue in higher education worldwide since 2008. Frankly speaking, there are clear pros and cons of moving into MOOC-based education. This chapter deals with the pedagogical utilization and limitations of MOOCs in higher education. Through literature review and websites surfing related to MOOCs, expansion of MOOCs, instructional strategies in MOOCs, functions of platform for MOOCs, development of a MOOC, and future of MOOCs are summarized, analyzed, and discussed at the aspect of pedagogy. Based on the analysis, some recommendations are suggested for the success of MOOCs.",signatures:"Sung-Wan Kim",downloadPdfUrl:"/chapter/pdf-download/53197",previewPdfUrl:"/chapter/pdf-preview/53197",authors:[{id:"187838",title:"Prof.",name:"Sung-Wan",surname:"Kim",slug:"sung-wan-kim",fullName:"Sung-Wan Kim"}],corrections:null},{id:"52803",title:"Massive Open Online Courses (MOOC) and Its Possibilities as Instrument of Formal, Nonformal, Informal and Lifelong Learning",doi:"10.5772/65930",slug:"massive-open-online-courses-mooc-and-its-possibilities-as-instrument-of-formal-nonformal-informal-an",totalDownloads:2313,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"In this chapter, we present the definition, development, and providers of massive open online courses (MOOC). We also explain the advantages and disadvantages of MOOC. We also present the structure of participants of MOOC, and also the motivation of participants is analyzed. Some basic statistics of realization and success of participants are also displayed. In one part of this chapter, the authors present case study of MOOC implementation in formal education in Belgrade Polytechnic (BP) College. For informal learning, a MOOC for welding is presented. This MOOC is planned to be organized on faculty of mechanical engineering at Belgrade University. During MOOC, participants also expanded their knowledge base and in that way they created possibilities for rerun of MOOC on a higher level. In that way, a participant can attend the same course after a couple of years and then will upgrade his knowledge. This attribute makes MOOC an instrument for lifelong learning.",signatures:"Srdjan Trajković, Radica Prokić-Cvetković and Olivera Popović",downloadPdfUrl:"/chapter/pdf-download/52803",previewPdfUrl:"/chapter/pdf-preview/52803",authors:[{id:"104246",title:"Dr.",name:"Olivera",surname:"Popović",slug:"olivera-popovic",fullName:"Olivera Popović"},{id:"106384",title:"Prof.",name:"Radica",surname:"Prokic-Cvetkovic",slug:"radica-prokic-cvetkovic",fullName:"Radica Prokic-Cvetkovic"},{id:"191211",title:"MSc.",name:"Srdjan",surname:"Trajković",slug:"srdjan-trajkovic",fullName:"Srdjan Trajković"},{id:"192158",title:"M.Sc.",name:"Srdjan",surname:"Trajković",slug:"srdjan-trajkovic",fullName:"Srdjan Trajković"}],corrections:null},{id:"52530",title:"Digital Factory and Virtual Reality: Teaching Virtual Reality Principles with Game Engines",doi:"10.5772/65218",slug:"digital-factory-and-virtual-reality-teaching-virtual-reality-principles-with-game-engines",totalDownloads:1998,totalCrossrefCites:0,totalDimensionsCites:2,hasAltmetrics:0,abstract:"Virtual reality (VR) is widely used in various industrial applications. All leading industrial manufacturing companies today have a strategy called the ‘concept of a digital factory’ where all aspects of manufacturing are digitally verified on digital mock-ups prior to physical manufacturing. Other than that, it is a rapidly developing new medium and further development of VR and IT will open up new possibilities. The new concept of Industry 4.0 is based on using approaches like the Internet of Things, Cloud Computing, Cyber-Physical Systems and Virtual Reality. With the decreasing cost of VR devices, even smaller businesses are able to implement such technologies. It is therefore crucial that mechanical engineering graduates are familiar with these new technologies and trends. We had to use unconventional methods to educate mechanical engineering students in the latest trends in IT and VR. Back in 2010, there were almost no tools available for teaching how to create industry-themed VR environments, which did not require complicated coding, so we decided to make our own. To simplify the development, we used Source Engine as the core and enhanced it with a library of textures, models and scripts we called DigiTov. Although Source Engine is a game engine, the master logic of VR development is the same as for professional SW products. In autumn 2015, a group of 10 students modified the DigiTov for Unity3D, forming a team made up of different roles.",signatures:"Petr Hořejší, Jiří Polcar and Lucie Rohlíková",downloadPdfUrl:"/chapter/pdf-download/52530",previewPdfUrl:"/chapter/pdf-preview/52530",authors:[{id:"189568",title:"Ph.D. Student",name:"Jiri",surname:"Polcar",slug:"jiri-polcar",fullName:"Jiri Polcar"},{id:"190239",title:"Dr.",name:"Petr",surname:"Horejsi",slug:"petr-horejsi",fullName:"Petr Horejsi"},{id:"194681",title:"Dr.",name:"Lucie",surname:"Rohlíková",slug:"lucie-rohlikova",fullName:"Lucie Rohlíková"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"7249",title:"3D Printing",subtitle:null,isOpenForSubmission:!1,hash:"bd92f056fb3bb4793bf7f07413747568",slug:"3d-printing",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/7249.jpg",editedByType:"Edited by",editors:[{id:"101330",title:"Dr.",name:"Dragan",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5707",title:"Computer Simulation",subtitle:null,isOpenForSubmission:!1,hash:"9eec1723d4d4775dc9755db55aa387a6",slug:"computer-simulation",bookSignature:"Dragan Cvetkovic",coverURL:"https://cdn.intechopen.com/books/images_new/5707.jpg",editedByType:"Edited by",editors:[{id:"101330",title:"Dr.",name:"Dragan",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6299",title:"Simulation and Gaming",subtitle:null,isOpenForSubmission:!1,hash:"e86eaf984e70e1544d594f7df43189ed",slug:"simulation-and-gaming",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/6299.jpg",editedByType:"Edited by",editors:[{id:"101330",title:"Dr.",name:"Dragan",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7753",title:"Interactive Multimedia",subtitle:"Multimedia Production and Digital Storytelling",isOpenForSubmission:!1,hash:"ec62348c48f21b53dc2896b6a58f81a5",slug:"interactive-multimedia-multimedia-production-and-digital-storytelling",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/7753.jpg",editedByType:"Edited by",editors:[{id:"101330",title:"Dr.",name:"Dragan",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6869",title:"Modeling and Computer Simulation",subtitle:null,isOpenForSubmission:!1,hash:"1c580aea0bda699dc79c012ee0f7b68d",slug:"modeling-and-computer-simulation",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/6869.jpg",editedByType:"Edited by",editors:[{id:"101330",title:"Dr.",name:"Dragan",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10857",title:"Augmented Reality and Its Application",subtitle:null,isOpenForSubmission:!1,hash:"5d66e2c09cddac7cc377ffb103aa7ef9",slug:"augmented-reality-and-its-application",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10857.jpg",editedByType:"Edited by",editors:[{id:"101330",title:"Dr.",name:"Dragan",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8697",title:"Virtual Reality and Its Application in Education",subtitle:null,isOpenForSubmission:!1,hash:"ee01b5e387ba0062c6b0d1e9227bda05",slug:"virtual-reality-and-its-application-in-education",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/8697.jpg",editedByType:"Edited by",editors:[{id:"101330",title:"Dr.",name:"Dragan",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7824",title:"Numerical Modeling and Computer Simulation",subtitle:null,isOpenForSubmission:!1,hash:"603fad5bcae90ad8484397ca63b0e2e7",slug:"numerical-modeling-and-computer-simulation",bookSignature:"Dragan M. Cvetković and Gunvant A. Birajdar",coverURL:"https://cdn.intechopen.com/books/images_new/7824.jpg",editedByType:"Edited by",editors:[{id:"101330",title:"Dr.",name:"Dragan",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2728",title:"Distance Education",subtitle:null,isOpenForSubmission:!1,hash:"3c5e98262becf8a16cf297b68056ee6a",slug:"distance-education",bookSignature:"Paul Birevu Muyinda",coverURL:"https://cdn.intechopen.com/books/images_new/2728.jpg",editedByType:"Edited by",editors:[{id:"93065",title:"Dr.",name:"Paul",surname:"Birevu Muyinda",slug:"paul-birevu-muyinda",fullName:"Paul Birevu Muyinda"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],ofsBooks:[]},correction:{item:{id:"64729",slug:"erratum-toward-the-development-of-a-monitoring-and-feedback-system-for-predicting-poor-adjustment-to",title:"Erratum - Toward the Development of a Monitoring and Feedback System for Predicting Poor Adjustment to Grief",doi:null,correctionPDFUrl:"https://cdn.intechopen.com/pdfs/64729.pdf",downloadPdfUrl:"/chapter/pdf-download/64729",previewPdfUrl:"/chapter/pdf-preview/64729",totalDownloads:null,totalCrossrefCites:null,bibtexUrl:"/chapter/bibtex/64729",risUrl:"/chapter/ris/64729",chapter:{id:"57127",slug:"toward-the-development-of-a-monitoring-and-feedback-system-for-predicting-poor-adjustment-to-grief",signatures:"Wan Jou She, Laurie Burke, Robert A. Neimyer, Kailey Roberts,\nWendy Lichtenthal, Jun Hu and Matthias Rauterberg",dateSubmitted:"September 5th 2017",dateReviewed:null,datePrePublished:null,datePublished:"October 18th 2017",book:{id:"6456",title:"Proceedings of the Conference on Design and Semantics of Form and Movement",subtitle:"Sense and Sensitivity, DeSForM 2017",fullTitle:"Proceedings of the Conference on Design and Semantics of Form and Movement - Sense and Sensitivity, DeSForM 2017",slug:"proceedings-of-the-conference-on-design-and-semantics-of-form-and-movement-sense-and-sensitivity-desform-2017",publishedDate:"October 18th 2017",bookSignature:"Miguel Bruns Alonso and Elif Ozcan",coverURL:"https://cdn.intechopen.com/books/images_new/6456.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"156855",title:"Dr.",name:"Elif",middleName:null,surname:"Ozcan",slug:"elif-ozcan",fullName:"Elif Ozcan"}],productType:{id:"2",title:"Proceeding",chapterContentType:"conference paper",authoredCaption:"Edited by"}},authors:[{id:"221149",title:"Dr.",name:"Wan Jou",middleName:null,surname:"She",fullName:"Wan Jou She",slug:"wan-jou-she",email:"lave@lavendershe.com",position:null,institution:null}]}},chapter:{id:"57127",slug:"toward-the-development-of-a-monitoring-and-feedback-system-for-predicting-poor-adjustment-to-grief",signatures:"Wan Jou She, Laurie Burke, Robert A. Neimyer, Kailey Roberts,\nWendy Lichtenthal, Jun Hu and Matthias Rauterberg",dateSubmitted:"September 5th 2017",dateReviewed:null,datePrePublished:null,datePublished:"October 18th 2017",book:{id:"6456",title:"Proceedings of the Conference on Design and Semantics of Form and Movement",subtitle:"Sense and Sensitivity, DeSForM 2017",fullTitle:"Proceedings of the Conference on Design and Semantics of Form and Movement - Sense and Sensitivity, DeSForM 2017",slug:"proceedings-of-the-conference-on-design-and-semantics-of-form-and-movement-sense-and-sensitivity-desform-2017",publishedDate:"October 18th 2017",bookSignature:"Miguel Bruns Alonso and Elif Ozcan",coverURL:"https://cdn.intechopen.com/books/images_new/6456.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"156855",title:"Dr.",name:"Elif",middleName:null,surname:"Ozcan",slug:"elif-ozcan",fullName:"Elif Ozcan"}],productType:{id:"2",title:"Proceeding",chapterContentType:"conference paper",authoredCaption:"Edited by"}},authors:[{id:"221149",title:"Dr.",name:"Wan Jou",middleName:null,surname:"She",fullName:"Wan Jou She",slug:"wan-jou-she",email:"lave@lavendershe.com",position:null,institution:null}]},book:{id:"6456",title:"Proceedings of the Conference on Design and Semantics of Form and Movement",subtitle:"Sense and Sensitivity, DeSForM 2017",fullTitle:"Proceedings of the Conference on Design and Semantics of Form and Movement - Sense and Sensitivity, DeSForM 2017",slug:"proceedings-of-the-conference-on-design-and-semantics-of-form-and-movement-sense-and-sensitivity-desform-2017",publishedDate:"October 18th 2017",bookSignature:"Miguel Bruns Alonso and Elif Ozcan",coverURL:"https://cdn.intechopen.com/books/images_new/6456.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"156855",title:"Dr.",name:"Elif",middleName:null,surname:"Ozcan",slug:"elif-ozcan",fullName:"Elif Ozcan"}],productType:{id:"2",title:"Proceeding",chapterContentType:"conference paper",authoredCaption:"Edited by"}}},ofsBook:{item:{type:"book",id:"10491",leadTitle:null,title:"Anaerobic Digestion in Built Environments",subtitle:null,reviewType:"peer-reviewed",abstract:"Anaerobic digestion of biomass to biogas, commonly occurring in natural anoxic ecosystems, is an excellent method for utilizing wastes and producing green energy. This book presents examples of local installations of AD, or their proposals, located at small factories, workplaces, and in rural areas and housing complexes. The facilities consider the specific nature of the region, site conditions, and specificity of the utilized wastes. They protect the environment and ensure dispersed energy production. The latter is of great economic significance due to its closeness to end customers. Small local installations expand the pool of renewable energy on a global scale.",isbn:"978-1-83969-224-6",printIsbn:"978-1-83969-223-9",pdfIsbn:"978-1-83969-225-3",doi:"10.5772/intechopen.92507",price:119,priceEur:129,priceUsd:155,slug:"anaerobic-digestion-in-built-environments",numberOfPages:130,isOpenForSubmission:!1,isSalesforceBook:!1,hash:"082ec753a05d6c7ed8cc5559e7dac432",bookSignature:"Anna Sikora",publishedDate:"November 3rd 2021",coverURL:"https://cdn.intechopen.com/books/images_new/10491.jpg",keywords:null,numberOfDownloads:1406,numberOfWosCitations:0,numberOfCrossrefCitations:1,numberOfDimensionsCitations:5,numberOfTotalCitations:6,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"October 28th 2020",dateEndSecondStepPublish:"December 1st 2020",dateEndThirdStepPublish:"January 30th 2021",dateEndFourthStepPublish:"April 20th 2021",dateEndFifthStepPublish:"June 19th 2021",remainingDaysToSecondStep:"a year",secondStepPassed:!0,currentStepOfPublishingProcess:5,editedByType:"Edited by",kuFlag:!1,biosketch:"Principal investigator of grant projects funded by the Polish institutions: The National Centre for Research and Development, The National Science Centre, and Ministry of Science and High Education. Dr. Anna Sikora cooperates with the industry and foreign and domestic research centers.",coeditorOneBiosketch:"A specialist in the Anaerobic Digestion process - molecular and technical aspects of microbiological biofuels production. Dr. Anna Detman connects her engineering, biochemical, and microbiological knowledge with experience in different laboratory scales to create innovative and applicable Science.",coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"146985",title:"Dr.",name:"Anna",middleName:null,surname:"Sikora",slug:"anna-sikora",fullName:"Anna Sikora",profilePictureURL:"https://mts.intechopen.com/storage/users/146985/images/system/146985.jpg",biography:"Anna Sikora is a microbiologist, professor at the Institute of Biochemistry and Biophysics (IBB) PAS, Warsaw, Poland, and a leader of the Laboratory of White Biotechnology, Warsaw, Poland. She is a graduate of the Faculty of Biology, University of Warsaw. She received her Ph.D. and postdoctoral degrees from IBB PAS. She specializes in research on anaerobic digestion, fermentation processes, biogases (biohydrogen and biomethane) production; microbial communities and nutritional interactions between microorganisms; microbial iron reduction; and mutagenesis and DNA repair in bacteria. She has authored experimental papers, book chapters, and conference reports. She cooperates with the sugar industry in the field of applied research on the development of a method to obtain hydrogen and methane during anaerobic digestion of byproducts and wastes from sugar production.",institutionString:"Polish Academy of Sciences",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"4",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Polish Academy of Sciences",institutionURL:null,country:{name:"Poland"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1405",title:"Waste Management",slug:"engineering-environmental-engineering-waste-management"}],chapters:[{id:"77550",title:"Acetogenic Pretreatment as an Energy Efficient Method for Treatment of Textile Processing Wastewater",slug:"acetogenic-pretreatment-as-an-energy-efficient-method-for-treatment-of-textile-processing-wastewater",totalDownloads:136,totalCrossrefCites:0,authors:[{id:"336840",title:"Associate Prof.",name:"nadimkhandaker",surname:"Khandaker",slug:"nadimkhandaker-khandaker",fullName:"nadimkhandaker Khandaker"},{id:"425795",title:"Dr.",name:"Mohammad Moshiur",surname:"Rahman",slug:"mohammad-moshiur-rahman",fullName:"Mohammad Moshiur Rahman"},{id:"425796",title:"Dr.",name:"De Salima",surname:"Diba",slug:"de-salima-diba",fullName:"De Salima Diba"}]},{id:"77247",title:"Evaluation of Physical and Chemical Pretreatment Methods to Improve Efficiency of Anaerobic Digestion of Waste Streams from Grain Processing",slug:"evaluation-of-physical-and-chemical-pretreatment-methods-to-improve-efficiency-of-anaerobic-digestio",totalDownloads:132,totalCrossrefCites:0,authors:[{id:"341131",title:"Dr.",name:"Jagannadh",surname:"Satyavolu",slug:"jagannadh-satyavolu",fullName:"Jagannadh Satyavolu"},{id:"414018",title:"Dr.",name:"Robert",surname:"Lupitskyy",slug:"robert-lupitskyy",fullName:"Robert Lupitskyy"}]},{id:"76068",title:"Employment of Organic Residues for Methane Production: The Use of Wastes of the Pulp and Paper Industry to Produce Biogas - A Case Study",slug:"employment-of-organic-residues-for-methane-production-the-use-of-wastes-of-the-pulp-and-paper-indust",totalDownloads:199,totalCrossrefCites:0,authors:[{id:"340723",title:"Dr.",name:"Alfredo de Jesús",surname:"Martinez Roldán",slug:"alfredo-de-jesus-martinez-roldan",fullName:"Alfredo de Jesús Martinez Roldán"},{id:"347374",title:"Dr.",name:"María Dolores Josefina",surname:"Rodriguez Rosales",slug:"maria-dolores-josefina-rodriguez-rosales",fullName:"María Dolores Josefina Rodriguez Rosales"},{id:"347589",title:"Dr.",name:"Sergio",surname:"Valle Cervantes",slug:"sergio-valle-cervantes",fullName:"Sergio Valle Cervantes"},{id:"347590",title:"MSc.",name:"Thania Azucena",surname:"Mendez-Perez",slug:"thania-azucena-mendez-perez",fullName:"Thania Azucena Mendez-Perez"}]},{id:"75926",title:"Small-Size Biogas Technology Applications for Rural Areas in the Context of Developing Countries",slug:"small-size-biogas-technology-applications-for-rural-areas-in-the-context-of-developing-countries",totalDownloads:405,totalCrossrefCites:0,authors:[{id:"231453",title:"Prof.",name:"Tareq",surname:"Abu Hamed",slug:"tareq-abu-hamed",fullName:"Tareq Abu Hamed"},{id:"339979",title:"Ph.D.",name:"Martina",surname:"Pilloni",slug:"martina-pilloni",fullName:"Martina Pilloni"}]},{id:"76942",title:"Techno Economic Studies on the Effective Utilization of Non-Uniform Biowaste Generation for Biogas Production",slug:"techno-economic-studies-on-the-effective-utilization-of-non-uniform-biowaste-generation-for-biogas-p",totalDownloads:285,totalCrossrefCites:1,authors:[{id:"259377",title:"Dr.",name:"Premalatha",surname:"Manickam",slug:"premalatha-manickam",fullName:"Premalatha Manickam"},{id:"269103",title:"Dr.",name:"Mariappan",surname:"Vairavan",slug:"mariappan-vairavan",fullName:"Mariappan Vairavan"},{id:"339136",title:"Dr.",name:"Godwin",surname:"Glivin",slug:"godwin-glivin",fullName:"Godwin Glivin"},{id:"415183",title:"Dr.",name:"Joseph",surname:"Sekhar Santhappan",slug:"joseph-sekhar-santhappan",fullName:"Joseph Sekhar Santhappan"}]},{id:"76104",title:"Innovative Designs in Household Biogas Digester in Built Neighbourhoods",slug:"innovative-designs-in-household-biogas-digester-in-built-neighbourhoods",totalDownloads:251,totalCrossrefCites:0,authors:[{id:"340232",title:"Ph.D. Student",name:"Martha",surname:"Osei-Marfo",slug:"martha-osei-marfo",fullName:"Martha Osei-Marfo"},{id:"343562",title:"Dr.",name:"Isaac",surname:"Mbir Bryant",slug:"isaac-mbir-bryant",fullName:"Isaac Mbir Bryant"}]}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"247865",firstName:"Jasna",lastName:"Bozic",middleName:null,title:"Ms.",imageUrl:"https://mts.intechopen.com/storage/users/247865/images/7225_n.jpg",email:"jasna.b@intechopen.com",biography:"As an Author Service Manager, my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"5718",title:"Coal Fly Ash Beneficiation",subtitle:"Treatment of Acid Mine Drainage with Coal Fly Ash",isOpenForSubmission:!1,hash:"7862b773bc74f187c6a6b5abee7f278d",slug:"coal-fly-ash-beneficiation-treatment-of-acid-mine-drainage-with-coal-fly-ash",bookSignature:"Segun A. Akinyemi and Mugera W. Gitari",coverURL:"https://cdn.intechopen.com/books/images_new/5718.jpg",editedByType:"Edited by",editors:[{id:"147114",title:"Dr.",name:"Segun",surname:"Akinyemi",slug:"segun-akinyemi",fullName:"Segun Akinyemi"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8453",title:"Lean Manufacturing and Six Sigma",subtitle:"Behind the Mask",isOpenForSubmission:!1,hash:"9342a056651f34acc565b467a71e1e27",slug:"lean-manufacturing-and-six-sigma-behind-the-mask",bookSignature:"Fausto Pedro García Márquez, Isaac Segovia Ramirez, Tamás Bányai and Péter Tamás",coverURL:"https://cdn.intechopen.com/books/images_new/8453.jpg",editedByType:"Edited by",editors:[{id:"22844",title:"Prof.",name:"Fausto Pedro",surname:"García Márquez",slug:"fausto-pedro-garcia-marquez",fullName:"Fausto Pedro García Márquez"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"314",title:"Regenerative Medicine and Tissue Engineering",subtitle:"Cells and Biomaterials",isOpenForSubmission:!1,hash:"bb67e80e480c86bb8315458012d65686",slug:"regenerative-medicine-and-tissue-engineering-cells-and-biomaterials",bookSignature:"Daniel Eberli",coverURL:"https://cdn.intechopen.com/books/images_new/314.jpg",editedByType:"Edited by",editors:[{id:"6495",title:"Dr.",name:"Daniel",surname:"Eberli",slug:"daniel-eberli",fullName:"Daniel Eberli"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"57",title:"Physics and Applications of Graphene",subtitle:"Experiments",isOpenForSubmission:!1,hash:"0e6622a71cf4f02f45bfdd5691e1189a",slug:"physics-and-applications-of-graphene-experiments",bookSignature:"Sergey Mikhailov",coverURL:"https://cdn.intechopen.com/books/images_new/57.jpg",editedByType:"Edited by",editors:[{id:"16042",title:"Dr.",name:"Sergey",surname:"Mikhailov",slug:"sergey-mikhailov",fullName:"Sergey Mikhailov"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1373",title:"Ionic Liquids",subtitle:"Applications and Perspectives",isOpenForSubmission:!1,hash:"5e9ae5ae9167cde4b344e499a792c41c",slug:"ionic-liquids-applications-and-perspectives",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/1373.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"78394",title:"Object Recognition and Tracking Using the Particle Estimator",doi:"10.5772/intechopen.99615",slug:"object-recognition-and-tracking-using-the-particle-estimator",body:'
1. Introduction
The first step in tracking object in an image sequence is to identify the reference object to be tracked; this will allow determining its attributes to carry out its identification by means of some of the main characteristics of the image of the object, such as the characteristics points. It should be noted that if is known: the initial position of the object to be tracked in the camera coordinates and the mathematical model of the camera, it is possible, in addition to tracking the object, to estimate its coordinates and moving in this reference system. One of the techniques applied for object tracking to which we will particularly refer is the particle estimator. This technique is a special type of Monte Carlo sequential method, one of its main advantages being its applicability to any model of transition of states and observations, especially when these are non-linear and non-Gaussian [1]. Although the Kalman estimator, which is applied to systems where the system evolution and measurement models are linear, with Gaussian noise, and with known mean and variance; has extensions to nonlinear models by applying techniques to achieve linearity, the Gaussian additive noise constraint cannot be overcome [1, 2].
Therefore, the particle estimators do not have the restrictive hypothesis of the Kalman estimator, so they can be applied to non-linear models with non-Gaussian and multimodal noise, where the reliable numerical estimate is a function of an adequate number of samples [3].
This estimator distributes N particles over the image, and the observations made on each one of them update their probability of validating a hypothesis, that is, they use all the available information to reduce the uncertainty present in an inference or decision problem [2]. In some cases where the images are not clear or noisy, particularly those acquired through infrared cameras, it is necessary to make an improvement before applying the estimator; generally this improvement is based on a reduction in the incidence of the background image, for the special case of infrared images subtracting the value from the mean intensity and modifying its histogram to increase the contrast result a good choice.
Faced with rapid and unpredictable movements of the referent or the camera, the resampling process considers a scattering value based on the number of valid particles, so that the area covered during tracking is dynamically modified. Basically, the particle estimator provides us with a framework, in which it is possible to insert different algorithms for the recognition of the reference image in each particle; some of them are SURF, BRIEF, ORB, etc. These algorithms have the ability to generate a set of invariant features against some image variations, such as: scaling, rotation, illumination and with robustness against occlusion conditions.
2. Particle estimator tracking
To define the state estimation problem let us consider the system model, composed of the state evolution and observation models described by the following equations:
Xk=fXk−1vk−1,E1
Zk=hXknk.E2
Where XϵRn contains all the state variables that will be dynamically estimated, f is the non-linear function of the state variables, vϵRn represents the state noise system, ZϵRn are all observations related with the state variables by (Eq. (2)), nϵRn is the measurement noise, and h is known as an observation model. Remembering that Pab is the conditional probability of a if b, then the evolution and observation models given by (Eqs. (1) and (2)) are based on the following hypotheses referring to the following sequences [2, 4]:
Xk,k=1,2,… is a Markov process
PXkX0,X1,…Xk−1=PXkXk−1,E3
Zk,k=1,2,… is a Markov process regarding the historical data of X such that
PZkX0,X1,…Xk=PZkXk,E4
and the sequence of past observations only depends on its history, that is
PXkXk−1,Zk−1=PXkXk−1.E5
Considering that the system and observation noises vi∧vjandni∧nj are mutually independent of i∧j and also the initial state for all i≠j; and on the other hand we know that PX0Z0=PX0, then, the two-step Bayesian estimator, prediction and update allows us to obtain the probability density PXiZi=PXi [3, 5].
The particle estimator represents the posterior probability density of a random set of samples with their probabilities of validation with the hypothesis, so it is possible to estimate the most likely particle from this set. When we make the number of particles approaches to infinity this process approaches to the a posteriori likelihood function, and the solution approaches an optimal Bayesian estimator [5].
To go into the details of the particle estimator for object tracking, we will rely on the importance sampling method, taking a set of samples from the state space, which characterizes the a posteriori probability density function pX0:kZ1:k for the state:
X0:ki=Xii=0…k,E6
while that the corresponding observations are Z0:k=Zii=0…k, then, the a posteriori density in tk can be approximated by:
pX0:kZ1:k≈∑i=1NWkiδX0:k−X0:ki,E7
where δ. is Dirac’s delta function, N the total number of particles and Wkii=1N are the assigned weighting.
Considering the hypotheses corresponding to the expressions (Eqs. (1) and (2)) the density a posteriori (Eq. (7)) can be written as [6, 7]:
pXkZ1:k≈∑i=1NWkiδXk−Xki,E8
and the evaluation of the weights within the importance sampling principle assumes that there is an evaluable probability density function pX such that:
WkiαpXkZ1:kE9
and Wki are normalized according to (Eqs. (10) and (11)).
∑i=1NWki=1,∴E10
Wki=wkXi=1:ni∑j=1NwkXj=1:njE11
This algorithm has a common problem known as the degeneracy phenomenon, which manifests itself after a few states, where all but a few particles (usually one) have negligible weight [3, 6]. This can be solved resampling the particles, however this creates another problem, which is the increasing information uncertainty arising in the random sampling process [8]. However, this problem can be detected by means of what is known as the effective sample size Neff, which can be estimated by means of the (Eq. (12)).
Neff=1∑i=1NWki2E12
When all particles have the same weight, i.e. Wki=1N, for =1,…,N, then the effectiveness is maximum and equal to Neff=N, but in the case where all but one particle has zero weight, the effectiveness is minimum and equal to Neff=1 [7].
While the correct choice of the probability density function pX to evaluate the particles weights (Eq. (9)), minimizes the problem of the degeneracy phenomenon; but to solve it, a resampling has to be incorporated into the algorithm; this incorporation is known as the Sequential Importance Resampling (SIR). This technique is applied in the case where the effective sample size Neff falls below a threshold value NT, its effect is to remove particles with small weights and replicate those with greater weights.
2.1 Particle estimator algorithm
In the following, we describe the six steps of the particle estimator algorithm applied to video object tracking:
Design:
An observation function Ηk, used for the evaluation of the similarity probability for each particle with the referent object.
Determine whether image pre-processing is required.
The number of particles N.
The threshold number of particles Neff, to determine which type of resampling strategy to use.
The noise distribution function χk, applied for resampling.
Initialization:
Identification on the image the object to be tracked in its position and size; this operation is performed by the user and defining the reference particle.
Determination of its main characteristics by means of the observation function Ηk; generating the information for the identification of the reference particle.
Generation of a set of N particles in random position over the whole image, if there is a priori information of its location; this is used for the positioning of the particles centered on it, and over this a random distribution.
The set of particles are initialized with the normalized weights, with the same values Wk=1N.
Update:
For each particle, their normalized weights are calculated, based on the state probability of similarity to the reference.
From the particles set, extract a sub set with the particles most likely to match the reference particle.
With the subset of particles most likely to match the reference particle, the most probable location and size of the object is determined a priori.
Resampling:
The effective number of particles Neff is evaluated, and if it is lower than the threshold value NT, the lowest weight particles are discarded.
From this new subset of particles most likely to match the reference particle, the new set of N particles for the next state is created.
The state of this new set of particles is modified by introducing the additive noise χk, that brings variability to the system.
Completion:
You are returned to the Update stage c), as long as the data sequence is not finished.
2.2 Observation function
Observation functions are those that allow me to extract the main characteristics of an image. In the particle estimator they are used to obtain the main characteristics of the reference image and those of the particles. These sets of main characteristics allow determine the probability of similarity between the reference and each particle. Some of the main algorithms are described below.
2.2.1 Features from accelerated segment test (FAST) algorithm
The FAST algorithm is basically searching over the whole image the points where the changes in intensity in all directions are significantly (corner detection method) [9]. The principal advantage of this algorithm is its high speed performance, and is very suitable for real time applications in computer vision processing. Exist several technics to find a characteristic point in an image; two of this is described below.
In the first one, and as parameters of the algorithm, a threshold value T and a radius r are defined for the evaluation. On the pixel p to evaluate and which has an intensity Ip, a Bresenham circle of radius r is considered (see Figure 1).
Figure 1.
A Bresenham circle of radius r.
This circle of radius r defines a set of N points, if in this circle there is a set of n pixels whose inensity is greater than Ip+T or less than Ip−T, then the pixel p can be considered as a characteristic point. The values taken by the authors after the experimental results are: n≥0.75N to consider a pixel p as a characteristic point, and the value of the radius r=3, which defines N=16 and n=12.
In a first step, the intensity Ip of pixel p is compared with the intensity of the pixels 1, 5, 9, and 13, if 3 of these 4 pixels meet the threshold criteria, then it is checked if there are at least 12 pixels that meet with this criteria to consider it as a characteristic pixel.
This procedure must be repeated for all pixels in the image and its drawbacks are: for values of n<12 a large number of characteristics points are generated, and having to evaluate all points of the circle slows down the algorithm. To improve the speed of the algorithm a proposal of the authors is to give it a machine learning approach [10].
In the second one, known as Fast Radial Blob Detector (FRBD), the technique consists of applying the Gaussian Laplacian filter to an image Ixy, the Laplacian operator, as well as detecting the edges very well also detects the noise very well [11]. Therefore a Gaussian filter must be previously applied to the image to reduce its noise level; a Gaussian kernel of width σ to convolve with the image is represented by the (Eq. (13)) to suppress the noise before using Laplace for edge detection (Eq. (14)), and finally (Eq. (15)) represent the kernel of the Gaussian Laplacian filter to convolve with the image (Eq. (16)).
Gxyσ=12πσ2e−x2+y22σ2E13
Lxy=∇2Ixy=d2Ixydx2+d2Ixydy2E14
LoGxy=ΔGxyσ=d2Gxyσdx2+d2Gxyσdy2E15
LoGxyσ=ΔGxyσ∗IxyE16
This kernel ΔGxyσ showed in Figure 2, is a feature detector because it finds regions where the image gradients are changing quickly for example blobs, corners and edges.
Figure 2.
Kernel of the Gaussian Laplacian filter.
This FRBD algorithm goes one step further by using a second-order finite-difference approximation on the filtered image. An approximation to the LoG but which can be computed more rapidly is the Difference of Gaussian (DoG) operator, this approximation using a second-order finite differencing which estimates how the filtered image changes at a given pixel. A circle of radius r is constructed with center in a pixel p, and sampled pixels in eight discrete directions are evaluated, refer to the central pixel (Figure 3).
Figure 3.
Eight discrete directions of the sampled pixels.
Using the sample points P0…8 compute the average pixel difference around pixel P0 as,
Fxyr=abs∑1=18P0−PiE17
The average pixel difference (Eq. (17)) is identical to convolving the original image with the kernel of the Figure 2.
The features are extracted maximizing the rate of change of Fxyr respect to r, calculate as first order differencing,
Rxyr=Fxyr−Fxyr−1E18
if R(x, y, r) is multiplied by the minimum pixel difference,
Fminxyr=miniP0−PiE19
the pixels that no exhibit changes in intensity in all directions are suppressing.
2.2.2 Speeded-up robust features (SURF) algorithm
The particularity of this algorithm is its ability to determine the characteristics points in an image, which are invariant to changes in: scale, rotations and translations, and partially to illumination changes. This algorithm is an optimization of the Scale Invariant Feature Transform (SIFT) algorithm [12], being its execution speed much higher than the latter [13]. On the other hand, the SURF algorithm produces less information that the SIFT for each characteristic point of the image, although the produced information by the SURF algorithm is more than enough for most applications, including the present one.
The use of integral images in this algorithm makes it very fast to represent at different scales of the original image its differential features. Integral images accelerate the computation at different scales the application of Haar wavelets, and together with the application of the Hessian differential operator allows the determination of key points and their robust descriptor features [2, 11].
Given an image I, and a point X=xy in this image, the Hessian matrix HXσ in X=xy to the scale σ is defined as:
HXσ=Lx,x,XσLy,x,XσLx,y,XσLy,y,Xσ,E20
where Lx,x,Xσ, Lx,y,Xσ, Ly,x,Xσ and Ly,y,Xσ represent the convolution product of the second derivative of the Gaussian ∂2∂X2gXσ with the Image I in the point X=xy [12], see (Eq. (22)).
Lx,x,Xσ=∂2∂X2∗Gxyσ∗IxyE21
Lx,x,Xσ=∂2∂X2∗Gxyσ∗IxyE22
∧Gxyσ=12πσ2e−x2+y22σ2E23
The determinant of the Hessian matrix allows the calculation of the scale of the point, defined as follows:
HXσ=Dx,xDy,y−ωDx,y2,E24
where Dx,x, Dy,y, and Dx,y=Dy,x are the approximations of the partial derivatives, and ω is the balance factor of the determinant [2], obtained from (Eq. (25)) where .F is the Frobenius norm [3], see (Eq. (26)).
w=Lx,y,XσFDy,yFLy,y,XσFDx,yFE25
AF=∑i=1m∑j=1nai,j2E26
Applying the Haar-Wavelet filters in a circular area of radius 6s provides us a set of outputs in both directions (dx and dy respectively), and the mean value of those responses as a dominant direction within the sliding area of π/3 [12].
Finally the feature descriptors for a certain scale and for each characteristic point are obtained. To do this a rectangular area of 20σx20σ centered on the point is constructed in the dominant orientation. This is divided into four sub-regions of 4x4, and for each sub-region the Haar-Wavelet is applied obtaining the horizontal dx and vertical dy responses. A characteristic vector V is formed, and then for each point a total of 64 SURF descriptors are generated [10, 11],
V=∑dx∑dy∑dx∑dy.E27
2.2.3 Binary robust independent elementary features (BRIEF) algorithm
In terms of execution time, the SURF algorithm performs better than SIFT, but this is not sufficient for current applications for real-time processing of video streams in navigation, augmented reality, etc. To satisfy these applications simpler concepts are applied in algorithms for obtaining fast detectors and descriptors, such as: FAST [14], FASTER [15], CenSurE [16], and SUSurE [17] are some examples of them.
In particular the BRIEF descriptor, like SURF, uses the integral image and applies to a set of very simple binary tests which are adequate to the use of the Hamming distance (distance between two code words, is the number of bit positions in which they differ). This distance is much simpler and faster to evaluate than the Euclidean distance. It is also demonstrated in a practical way that a 32-dimensional BRIEF descriptor achieves similar results to a 64-dimensional SURF descriptor.
This algorithm obtains the descriptors of the characteristics points of the image, and for this a defining a neighboring area centered on this points, this area is known as patch p, which is square and a few pixels high and wide LxL (see Figure 4).
Figure 4.
Patch in an image over a specific key point.
Since, the BRIEF algorithm handles pixel intensity levels this makes it very sensitive to noise, therefore it is necessary to pre-smooth the patch to reduce the sensitivity and increase the accuracy of the descriptors. Is for that, after create a patch centered on the feature point a smooth Gaussian filter is applied to the patch (Eq. (28)),
fxy=12πσ2e−x2+y22σ2.E28
BRIEF converts the patches into a binary vector representative of it, this descriptor containing only 1 and 0, so each descriptor of a characteristic point is a string of 128–512 bits. After applied the smoothing to the patch p by (Eq. (16)) the patch is converted to binary feature vector as responses of binary test τ, which is define by (Eq. (29)),
τpxy=1:px<py0:px≥pyE29
where px is the intensity value of the pixel at point x; then a set of nxy with n equal to 128, 256 or 512, and the location pairs (see Figure 4) must be defined as a set of binary tests uniquely. The pixel pxy is located inside the patch, and it is called random pair, for creating a binary feature vector of number nis necessary select the random pairs; the most useful functions to this selection are the following five, showed in (Eq. (30)).
The advantages characteristics of the BRIEF descriptor are: high-speed processing, little memory usage and strong to illumination and blur change, and disadvantages are: weak to the rotation of the viewpoint, and the change in the position of a light source.
The (Eq. (31)) describes the BRIEF descriptor, but in its application must be in consideration that its matching performance falls sharply with a few degrees in plane rotation.
fnp=∑i=1n2i−1.τpxiyiE31
2.2.4 Oriented FAST and rotate BRIEF (ORB) algorithm
The main characteristics of the ORB algorithm compared to its equivalents SIFT and SURF are that the ORB performs the feature detection operations as well as these but with a superior performance; having as an additional advantage that its use is free. It is based on the widely proven FAST and BRIEF algorithms, very good performance and low computational cost.
As the FAST algorithm does not have information about features of orientation and multi-scale, these must be implemented. For the multi-scale response, a scale pyramid is generated, where each level of the pyramid contains a version of the original image but at a lower resolution (Figure 5).
Figure 5.
Multiscale scheme for an image.
Applying to each level (scale) the FAST algorithm (see 2.1.1) we obtain the characteristics points at each level (vertices); as this algorithm also responds to edges, these must be discarded. For this we use the Harris algorithm with a low threshold [18], in order to obtain a large number of characteristic points, which are ordered according to the Harris measure to obtain the desired number of main points.
From there, the orientation is done by means of the intensity centroid [19], which assumes that the intensity of a corner is different from that of its center, and the vector formed between both points is used to calculate its orientation. Rosin defines the moments of a patch by means of (Eq. (32)) as,
mp,q=∑x,yxp.yq.IxyE32
and with these moments we can find the centroid by (Eq. (33)),
C=m1,0m0,0m0,1m0,0.E33
While the orientation of the patch can be calculated by means of the vector OC→ with origin at the center C of the patch and a point O on its periphery, and is obtained by means of (Eq. (34)),
θ=atan2m0,1m1,0.E34
To improve the invariance of this measurement we must ensure that the calculation of the moments is performed with x and y included in a circular region of radius r contained within the patch.
The table of features for each characteristics point is determined by means of the steered BRIEF method [20], according to the orientation θ of the patch at that point. For each characteristics point xiyi we define a 2xn matrix S (Eq. (35)), and a rotation matrix Rθ as function of the orientation θ of the patch, obtaining an oriented version of the matrix Sθ by (Eq. (36)).
S=x1…xny1…ynE35
Sθ=RθSE36
Obtaining the operator steered BRIEF as,
gnpθ=fnpxiyi∈Sθ,E37
where fnp is the binary test operator obtained from (Eq. (31)).
To construct the BRIEF pattern search table, the angle θ is discretizing in increments of 2π/3012degrees. All previous tests are ordered by their distance from a mean of 0.5 generating a vector T. Then the first test of T is taken and added to the table of results R, from there the next test of the vector T is taken and compared with all the tests results in R, if its absolute correlation is less than a threshold it is discarded, otherwise it is added to the table of results R, until a total of 256 tests are obtained.
3. Processes in the particle estimator algorithm
Basically this method deploys in the image a series of random particles, possible states of the process in this case the target position and its size; while their weights represent their posteriori probability of the density functions as an estimated from the observations. One of the particularities of the particle estimator is the number of configuration parameters it has, and to optimize its performance, in terms of estimation quality and processing time, they must be properly chosen. Some of these parameters refer to the behavior of the estimator itself and others to the behavior of the SURF algorithm (used here for infrared images), as described below.
For the behavior of the particle estimator:
Maximum number of particles,
Probability threshold to consider a particle valid,
Adaptability in the standard deviation as a function of the number of valid particles for the vector of states in the resampling.
For the behavior of the SURF algorithm:
Maximum number of characteristics points to be considered,
Number of scale level, controls the number of filters used per octave,
The threshold for the determination of the number of blobs to detect,
Number of octaves, controls the filters and subsample of the image data; larger number of octaves will result in finding larger size blobs.
Then, and for the case of this application (tracking objects in video images) we can describe the processes implemented following the guidelines of the algorithm described in 2.1.
3.1 Initialization
Mainly in this step, the reference particle to follow is selected, and all the parameters described in the previous paragraph are initialized with the design values.
3.2 Particle description
The particle was described by means of a rectangle; and to characterize it we define a state vector for each particle (Eq. (38)).
X=xywhẋẏẇḣT=pvTE38
This state vector contains the positions xy and for its size, lengths of width and height wh, while for its velocities ẋẏ and ẇḣ respectively.
The velocity of the particle is calculated by means of the difference between pk+1−pk divided by the time video sampling, at the end of the cycle.
When a new frame is acquired, the particles are propagated following state evolution model in correspondence with (Eq. (1)):
Pk=APk−1+Avk−1,E39
A=I4x4Δt.I4x404x4I4x4,E40
where I4x4 is the 4x4 identity matrix, 04x4 is the 4x4 null matrix and Δt is the frame sample time. After the particle propagation the bounds check is applied to verify that all the particles are within the image.
3.3 Particle probabilities estimation
The determination of the similarity between each particle and the reference depends on the type of image, either color or black and white. The images in this text are in black and white from images acquired from infrared sensors, but we will pause here to consider a color image.
3.3.1 Color images
In the case of the color image to determine the similarity with the reference the distance between histograms is used, in the example of the Figure 6 the Bhattacharyya distance [21] for histograms (Eq. (41)) was used, instead of Euclidean distance, because a better response was obtained.
Figure 6.
Airplane sequence of the particle estimator, where [a .. h] correspond to sequences between [4s .. 4.32s].
Bdst=∑hIr−hIr¯.hI−hI¯∑hIr−hIr¯2.∑hI−hI¯2E41
Where Bdst is the Bhattacharyya distance, hIrandhI the histogram to be compared, and hIr¯andhI¯ its mean values. The probability of one is obtained when the sum of the three distances between the red, green and blue histograms, is equals to zero.
Figure 7 shows the sequence of images for the tracking of a person, in which the particles can be seen in three colors, green for the best estimation, blue for the most probable particles, and red for the least probable ones. At 3.399 seconds the action of the increase dispersion parameter in the resampling procedure is observed, due a low number of valid particles; this is maintained only in two frames, returned to normal values quickly.
Figure 7.
Person tracking, sequence of the particle estimator.
3.3.2 Black and white images
In the case of the black and white images, for determining the similarity between each particle with the reference, the SURF algorithm was used. Before applying the SURF algorithm, the background effect is reduced, generally this improvement is based on subtracting the value from the mean intensity and modifying its histogram to increase the contrast result a good choice for infrared images. In this case and for this type of image the procedure used to enhance the image of the object was: first subtract the input image IP by a proportional factor α to its mean value I, second multiply the result by a proportional factor β to the relationship between the standard deviation of the image (as measurement of the contrast) divided by the maximum value of the luminosity (Eq. (42)).
IP=I−α∑i=1,j=1N,MIijβσImaxI,E42
where, N and M are the number of pixels X and Y respectively, σI and maxI the standard deviation and the maximum value of image respectively. The adaptive factors α and β are obtained experimentally and the best results was obtained with values of α=0.84314and β=25.
For determining the similarity of a particle with the reference particle, a pairing of the characteristic points is performed. After this pairing, the numbers of pairs of points whose metric is less than a threshold metric are counted; and the relationship between the numbers of pairs of points with respect to the total number of characteristic points of the reference particle gives us its similarity probability.
3.4 Position and size of the object to be tracked
The position and size of the object to be tracked is determined by means of the most significant particles, i.e. those particles whose probability exceeds the selected probability threshold.
3.5 Re-sampling
From the most probable particle obtained in the previous step, a new particle set is distributed according to the dispersion of each variable, always limiting them to the size of the screen. But the dispersion of the variables is adapted according to the number of valid particles. This is implemented as a strategy of re-sampling, where the search zone is extended as function of the number of valid particles decreases.
4. Experimental results
Three experimental tests were performed with the previously described algorithm to tracking an object: a) an airplane; b) a six rotors “UAV” and c) a heliport. For the three experiments an infrared camera Tau 640, in the 8 to 14 micron band was used, in a) and b) experiments the camera was mounted on a positioning system, while in c) the camera was mounted on a six-rotor “UAV”, taking a zenithal image.
In case b), where the camera was mounted on a positioning system, this had a tracking system attached to it, so the values of the X and Y coordinates in pixels of the target could be obtained. Comparing them with those obtained from the particle estimator the error of the latter was determined.
The images obtained from the video frames were recorded sequentially according to the video acquisition frequency, and before applying the particle estimation algorithm, they were pre-processed by a background suppression and contrast enhancement procedure (Eq. (42)).
In all cases the same observation function, the SURF routine, was used to determine the likelihood of similarity between the video image and the reference image. The dispersion factors applied to the state vector in the resampling function vary inversely proportional to the number of valid particles, so that if the number of valid particles decreases, the search area increases.
4.1 Airplane tracking
The first experiment was the tracking of airplane, the estimator sequence can be observed in Figure 6, frame (a) correspond to the first sate of the estimator, distributed the particles over an area of the maximum probability of locate the target.
After the correct detection the particle estimator remains locked throughout the entire flight. As can be observed in frame (f) a lot of particle with probability under the threshold probability appears, but nevertheless remains lock.
4.2 Six rotors tracking
This experiment has the particularity of that the UAV to avoid detection flies hidden behind the trees, after which it starts a free flight. And in both cases the particle estimator is able to detect when only one part of its image visible. From the moment of the first detection the particle estimator remains locked throughout the entire flight. The Figure 8 shows part of the frames sequence of the flight, from left to right and from top to bottom the “UAV” first flying behind the trees, while the particle estimator begins distributing the particles in the largest possible area of the screen, after the third frame, and with the “UAV” still largely behind the trees, the particle estimator still able to detect it and “hook” it as soon as it partially appears.
Figure 8.
Six rotors “UAV” sequence of the particle estimator.
From the fourth frame the estimator remains locked during the whole flight, especially when the occlusion free flight is carried out, and the tracking is always right.
4.3 Heliport tracking
This experiment was a flight over a heliport located in a park area of the Institute, and the shots were taken from zenithal videos because an artificial vision navigation system was tested to aid the landing. The characteristics of these images are that they are interfered by infrared radiation from the ground, and the heliport is not properly marked.
The Figure 9 shows two sequences of the particle estimator execution, the upper correspond to the startup, and the lower in the middle of the experiment. From left to right and from top to bottom, the first frame corresponds to the initialization of the estimator, the particles are distributed over the whole image and the most probable particle in the center of the screen. In the second frame after 0.04 seconds (frame rate) only two particles have probability higher than the threshold, and it can be seen how the most probable particle reached the target. After that the estimator is locked, and remains in sequence of tracking.
Figure 9.
Heliport tracking sequence of the particle estimator.
5. Conclusions
The parameters that define the behavior of the particle estimator were described in paragraph 3. Although an analysis of the estimator’s response can be made based on each of these parameters; here we will perform only one, for the number of particles of the estimator.
For this purpose, we rely on the experiment corresponding to the tracking of the six-rotor UAV, because it was simultaneously tracked by a positioning system. Therefore, taking as true the observation obtained from the positioning system, it was possible to determine the relative error corresponding to the particle estimator.
To observe the dynamic response and the internal state of the particle estimator, the relative error (upper graph) and the number of valid particles (lower graph) as a function of time were plotted on Figure 10.
Figure 10.
Dynamic response of the particle estimator.
This figure show the behavior of the estimator, as a function of the number of particles and in different colors, for values of 30 (red), 50 (magenta), 70 (blue) and 90 (green), the time between marks is the acquisition video time, which is 0.050 seconds.
As can be seen always at least a number of 6 frames are needed to begin reach the lock state, and the number of particles parameter does not affect this number to get this state. But when the number of the particles of the estimator it increase, decreases its relative error, increase the computer time process, and presents greater stability to maintain the lock.
Another parameter that improved the particle estimator response is the dispersion multiplying factor of the state variables. This multiplying factor is increased when the number of valid particles decrease, covering a wider area of search in the image. With this search strategy the estimator maintains its stability in the response to the lock with the objective, in a few frames.
After several execution of the algorithm in the experiment b); and varying different initialization parameters of the estimator, the values that produce an acceptable behavior are: number of particles 70 or higher, number of characteristic points of the SURF algorithm 70 or higher, threshold value of probability of similarity 90% or higher.
With the considerations in the initialization parameters of the particle estimator mentioned above, the state lock could be maintained with no more than two frames unlocked. And another observed feature is that the estimator could track the target even when the object is mostly occluded on its surface, for example when the UAV is behind trees (see Figure 8).
As a proposed improvement to enhancement to achieve better detection of the target when it is mainly occluded, or when the image is heavily contaminated with noise; it is to reformulate the main strategy. This strategy consists of decomposing the reference image into NxN sub-images, in sequence and with their corresponding identification. And for each sub-image a particle estimator is applied, having NxN particle estimators, each one looking for a part of the reference image. From there and starting with the first particle, we look for the particles with more probability, and that are located in the correct sequence; the average of these particles will give us the more likely position of the target to be follow. In case that no particles are found in the correct positions we can obtain the most probability position of the object to be followed as the position of the particle with the largest probability, or as the integration of the information provided by the NxN estimators.
Acknowledgments
Special thanks to the Post Graduate staff of the National Technological University – Buenos Aires Regional Faculty. And the staff of the Laboratories of the Institute of Scientific and Technical Research for Defense: Thermal Imaging Laboratory for providing the images of the experience, and to the Digital Techniques Laboratory for carrying out the flight with the unmanned aerial vehicle.
Conflict of interest
The authors declare no conflict of interest.
\n',keywords:"recognition, tracking, estimator, image analysis, image processing",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/78394.pdf",chapterXML:"https://mts.intechopen.com/source/xml/78394.xml",downloadPdfUrl:"/chapter/pdf-download/78394",previewPdfUrl:"/chapter/pdf-preview/78394",totalDownloads:72,totalViews:0,totalCrossrefCites:0,totalDimensionsCites:0,totalAltmetricsMentions:0,impactScore:0,impactScorePercentile:0,impactScoreQuartile:0,hasAltmetrics:0,dateSubmitted:"July 6th 2021",dateReviewed:"July 22nd 2021",datePrePublished:"November 28th 2021",datePublished:"April 20th 2022",dateFinished:"September 1st 2021",readingETA:"0",abstract:"In this chapter we describe the particle estimators and its effectiveness for tracking objects in video sequences. The particles estimators are specifically advantageous in transition state models and measurements, especially when these are non-linear and not Gaussian. Once the target object to follow has been identified (in position and size) its main characteristics are obtained using algorithms such as FAST, SURF, BRIEF or ORB. As the particle estimator is a recursive Bayesian estimator, where observations update the probability of validating a hypothesis, that is, they use all the available information to reduce the amount of uncertainty present in an inference or decision problem. Therefore, the main characteristics of the object to follow are those that will determine the probability of validating the hypothesis in the particle estimator. Finally, as an example, the application of a particle estimator is described in a real case of tracking an object in a sequence of infrared images.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/78394",risUrl:"/chapter/ris/78394",book:{id:"10991",slug:"digital-image-processing-applications"},signatures:"Edgardo Comas and Adrián Stácul",authors:[{id:"417527",title:"Dr.Ing.",name:"Edgardo",middleName:null,surname:"Comas",fullName:"Edgardo Comas",slug:"edgardo-comas",email:"ecomas@frba.utn.edu.ar",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"425888",title:"Dr.",name:"Adrián",middleName:null,surname:"Stácul",fullName:"Adrián Stácul",slug:"adrian-stacul",email:"astacul@frba.utn.edu.ar",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"National Technological University",institutionURL:null,country:{name:"Argentina"}}}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Particle estimator tracking",level:"1"},{id:"sec_2_2",title:"2.1 Particle estimator algorithm",level:"2"},{id:"sec_3_2",title:"2.2 Observation function",level:"2"},{id:"sec_3_3",title:"2.2.1 Features from accelerated segment test (FAST) algorithm",level:"3"},{id:"sec_4_3",title:"2.2.2 Speeded-up robust features (SURF) algorithm",level:"3"},{id:"sec_5_3",title:"2.2.3 Binary robust independent elementary features (BRIEF) algorithm",level:"3"},{id:"sec_6_3",title:"2.2.4 Oriented FAST and rotate BRIEF (ORB) algorithm",level:"3"},{id:"sec_9",title:"3. Processes in the particle estimator algorithm",level:"1"},{id:"sec_9_2",title:"3.1 Initialization",level:"2"},{id:"sec_10_2",title:"3.2 Particle description",level:"2"},{id:"sec_11_2",title:"3.3 Particle probabilities estimation",level:"2"},{id:"sec_11_3",title:"3.3.1 Color images",level:"3"},{id:"sec_12_3",title:"3.3.2 Black and white images",level:"3"},{id:"sec_14_2",title:"3.4 Position and size of the object to be tracked",level:"2"},{id:"sec_15_2",title:"3.5 Re-sampling",level:"2"},{id:"sec_17",title:"4. Experimental results",level:"1"},{id:"sec_17_2",title:"4.1 Airplane tracking",level:"2"},{id:"sec_18_2",title:"4.2 Six rotors tracking",level:"2"},{id:"sec_19_2",title:"4.3 Heliport tracking",level:"2"},{id:"sec_21",title:"5. Conclusions",level:"1"},{id:"sec_22",title:"Acknowledgments",level:"1"},{id:"sec_25",title:"Conflict of interest",level:"1"}],chapterReferences:[{id:"B1",body:'Maybeck, Peter, Stochastic Models, Estimation and Control, vol. 3. Academic Press, Inc, 1982.'},{id:"B2",body:'Frank L. Lewis, LIHUA XIE, and Dan Popa, Optimal and Robust Estimation With an Introduction to Stochastic Control Theory, Second. 2008.'},{id:"B3",body:'David P. Landau, Kurt Binder, A Guide to Monte Carlo Simulations in Statistical Physics, Third Edition. Cambridge University Press, 2009.'},{id:"B4",body:'Jari Kaipio, Erkki Somersalo, Statistical and Computational Inverse Problems, Vol. 160. Springer Science, 2004.'},{id:"B5",body:'Arnaud Doucet and Adam M. Johansen, ‘A tutorial on particle filtering and smoothing’, Handb. Nonlinear Filter., vol. 12, Mar. 2012.'},{id:"B6",body:'Arnaud Doucet, Simon Godsill and Christophe Andrieu, ‘On sequential Monte Carlo sampling methods for Bayesian filtering’, Stat. Comput., Jul. 2000, DOI: 10.1023/A:1008935410038.'},{id:"B7",body:'Liu Jun and Chen Rong, ‘Sequential Monte Carlo Methods for Dynamic Systems’, J. Am. Stat. Assoc., Apr. 1998, DOI: 10.1080/01621459.1998.10473765.'},{id:"B8",body:'Fredrik Gustafsson, ‘Particle filter theory and practice with positioning applications’, IEEE Aerosp. Electron. Syst. Mag., vol. 25, no. 7, Jul. 2010, DOI: 10.1109/MAES.2010.5546308.'},{id:"B9",body:'Miroslav Trajkovii, Mark Hedley, ‘Fast corner detection’, Image Vis. Comput.'},{id:"B10",body:'Edward Rosten and Tom Drummond, ‘Machine Learning for High-Speed Corner Detection’. DOI: 10.1007/11744023_34.'},{id:"B11",body:'Charles Bibby and Ian Reid, ‘Fast Feature Detection with a Graphics Processing Unit Implementation’. University of Oxford, 2006.'},{id:"B12",body:'Herbert Bay, Tinne Tuytelaars, and Luc Van Gool, ‘speeded up robust features’, Comput. Vis. Image Underst., vol. 110, no. 3, Jun. 2008, DOI: 10.1016/j.cviu.2007.09.014.'},{id:"B13",body:'H. Kandil and A. Atwan, ‘A comparative study between SIFT-particle and SURF-particle’, Int. J. Signal Process. Pattern Recognit., Vol. 5, no. No 3, Sep. 2012.'},{id:"B14",body:'Edward Rosten and Tom Drummond., ‘Fusing points and lines for high performance tracking’, in IEEE International Conference on Computer Vision, Oct. 2005, vol. Volume 2.'},{id:"B15",body:'Edward Rosten, Reid Porter, and Tom Drummond, ‘A Machine Learning Approach to Corner Detection’, IEEE Trans Pattern Anal. Mach. Intell., 2010.'},{id:"B16",body:'Motilal Agrawal, Kurt Konolige, and Morten Rufus Blas, ‘CenSurE: Center Surround Extremas for Realtime Feature Detection and Matching’, Oct. 2008. DOI: 10.1007/978-3-540-88693-8_8.'},{id:"B17",body:'Mosalam Ebrahimi and Walterio Mayol-Cuevas, ‘Speeded Up Surround Extrema Feature Detector and Descriptor for Realtime Applications’, Jun. 2009.'},{id:"B18",body:'C. Harris and M. Stephens, ‘A Combined Corner and Edge Detector’, Presented at the Alvey Vision Conference, 1988. DOI: 10.5244/C.2.23.'},{id:"B19",body:'Paul L. Rosin, ‘measuring corner properties’, Comput. Vis. Image Underst., 1999, DOI: 10.1006/cviu.1998.0719.'},{id:"B20",body:'Vincent Lepetit, Pascal Fua and Christoph Strecha, ‘Binary Robust Independent Elementary Features’, CVLab, EPFL, Lausanne, Switzerland, May 2014. DOI: 10.1007/978-3-642-15561-1_56.'},{id:"B21",body:'Briñez de León, Juan CRetrepo Martinez, Alejandro López Giraldo, Francisco E., ‘Métricas de Similitud Aplicadas para Análisis de Imágenes de Fotoelasticidad’, Dyna, 2013 [Online]. Available: https://www.redalyc.org/articulo.oa?id=49627363006'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Edgardo Comas",address:"ecomas@frba.utn.edu.ar",affiliation:'
Institute of Scientific and Technical Research for Defense, Argentina
National Technological University – Buenos Aires Regional Faculty, Argentina
Institute of Scientific and Technical Research for Defense, Argentina
National Technological University – Buenos Aires Regional Faculty, Argentina
'}],corrections:null},book:{id:"10991",type:"book",title:"Digital Image Processing Applications",subtitle:null,fullTitle:"Digital Image Processing Applications",slug:"digital-image-processing-applications",publishedDate:"April 20th 2022",bookSignature:"Paulo E. Ambrósio",coverURL:"https://cdn.intechopen.com/books/images_new/10991.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83969-795-1",printIsbn:"978-1-83969-794-4",pdfIsbn:"978-1-83969-796-8",reviewType:"peer-reviewed",numberOfWosCitations:0,isAvailableForWebshopOrdering:!0,editors:[{id:"256064",title:"Dr.",name:"Paulo",middleName:"Eduardo",surname:"Ambrosio",slug:"paulo-ambrosio",fullName:"Paulo Ambrosio"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"601"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"80801",type:"chapter",title:"Digital Image Processing and Its Application for Medical Physics and Biomedical Engineering Area",slug:"digital-image-processing-and-its-application-for-medical-physics-and-biomedical-engineering-area",totalDownloads:27,totalCrossrefCites:0,signatures:"Nupur Karmaker",reviewType:"peer-reviewed",authors:[{id:"415856",title:"M.Sc.",name:"Nupur",middleName:null,surname:"Karmaker",fullName:"Nupur Karmaker",slug:"nupur-karmaker"}]},{id:"78646",type:"chapter",title:"Binarization Based on Maximum and Average Gray Values",slug:"binarization-based-on-maximum-and-average-gray-values",totalDownloads:24,totalCrossrefCites:0,signatures:"Saúl Manuel Domínguez Nicolás",reviewType:"peer-reviewed",authors:[{id:"417827",title:"Dr.",name:"Saúl Manuel",middleName:null,surname:"Domínguez Nicolás",fullName:"Saúl Manuel Domínguez Nicolás",slug:"saul-manuel-dominguez-nicolas"}]},{id:"78394",type:"chapter",title:"Object Recognition and Tracking Using the Particle Estimator",slug:"object-recognition-and-tracking-using-the-particle-estimator",totalDownloads:72,totalCrossrefCites:0,signatures:"Edgardo Comas and Adrián Stácul",reviewType:"peer-reviewed",authors:[{id:"417527",title:"Dr.Ing.",name:"Edgardo",middleName:null,surname:"Comas",fullName:"Edgardo Comas",slug:"edgardo-comas"},{id:"425888",title:"Dr.",name:"Adrián",middleName:null,surname:"Stácul",fullName:"Adrián Stácul",slug:"adrian-stacul"}]},{id:"78265",type:"chapter",title:"Performance Analysis of OpenCL and CUDA Programming Models for the High Efficiency Video Coding",slug:"performance-analysis-of-opencl-and-cuda-programming-models-for-the-high-efficiency-video-coding",totalDownloads:119,totalCrossrefCites:0,signatures:"Randa Khemiri, Soulef Bouaafia, Asma Bahba, Maha Nasr and Fatma Ezahra Sayadi",reviewType:"peer-reviewed",authors:[{id:"298629",title:"Dr.",name:"Randa",middleName:null,surname:"Khemiri",fullName:"Randa Khemiri",slug:"randa-khemiri"},{id:"304390",title:"Dr.",name:"Soulef",middleName:null,surname:"Bouaafia",fullName:"Soulef Bouaafia",slug:"soulef-bouaafia"},{id:"304391",title:"Dr.",name:"Fatma Ezahra",middleName:null,surname:"Sayadi",fullName:"Fatma Ezahra Sayadi",slug:"fatma-ezahra-sayadi"},{id:"426631",title:"Dr.",name:"Asma",middleName:null,surname:"Bahba",fullName:"Asma Bahba",slug:"asma-bahba"},{id:"426633",title:"Dr.",name:"Maha",middleName:null,surname:"Nasr",fullName:"Maha Nasr",slug:"maha-nasr"}]},{id:"79240",type:"chapter",title:"Weighted Module Linear Regression Classifications for Partially-Occluded Face Recognition",slug:"weighted-module-linear-regression-classifications-for-partially-occluded-face-recognition",totalDownloads:138,totalCrossrefCites:1,signatures:"Wei-Jong Yang, Cheng-Yu Lo, Pau-Choo Chung and Jar Ferr Yang",reviewType:"peer-reviewed",authors:[{id:"17726",title:"Prof.",name:"Pau-Choo",middleName:null,surname:"Chung",fullName:"Pau-Choo Chung",slug:"pau-choo-chung"},{id:"154856",title:"Prof.",name:"Jar-Ferr",middleName:null,surname:"Yang",fullName:"Jar-Ferr Yang",slug:"jar-ferr-yang"},{id:"418888",title:"Dr.",name:"Wei-Jong",middleName:null,surname:"Yang",fullName:"Wei-Jong Yang",slug:"wei-jong-yang"},{id:"419027",title:"Mr.",name:"Cheng-Yu",middleName:null,surname:"Lo",fullName:"Cheng-Yu Lo",slug:"cheng-yu-lo"}]},{id:"77357",type:"chapter",title:"Diffuse Optical Tomography System in Soft Tissue Tumor Detection",slug:"diffuse-optical-tomography-system-in-soft-tissue-tumor-detection",totalDownloads:138,totalCrossrefCites:0,signatures:"Umamaheswari Kumarasamy, G.V. Shrichandran and A. Vedanth Srivatson",reviewType:"peer-reviewed",authors:[{id:"341865",title:"Dr.",name:"Umamaheswari",middleName:null,surname:"Kumarasamy",fullName:"Umamaheswari Kumarasamy",slug:"umamaheswari-kumarasamy"},{id:"420180",title:"Dr.",name:"G.V.",middleName:null,surname:"Shrichandran",fullName:"G.V. Shrichandran",slug:"g.v.-shrichandran"},{id:"420181",title:"Mr.",name:"A.",middleName:null,surname:"Vedanth Srivatson",fullName:"A. Vedanth Srivatson",slug:"a.-vedanth-srivatson"}]}]},relatedBooks:[{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"36273",title:"Introduction to Infrared Spectroscopy",slug:"introduction-to-infrared-spectroscopy",signatures:"Theophile Theophanides",authors:[{id:"37194",title:"Dr.",name:"Theophile",middleName:null,surname:"Theophanides",fullName:"Theophile Theophanides",slug:"theophile-theophanides"}]},{id:"36166",title:"Using Infrared Spectroscopy to Identify New Amorphous Phases - A Case Study of Carbonato Complex Formed by Mechanochemical Processing",slug:"using-infrared-spectroscopy-to-identify-new-amorphous-phases-a-case-study-of-carbonato-complexes-fo",signatures:"Tadej Rojac, Primož Šegedin and Marija Kosec",authors:[{id:"25116",title:"Prof.",name:"Marija",middleName:null,surname:"Kosec",fullName:"Marija Kosec",slug:"marija-kosec"},{id:"105876",title:"Dr.",name:"Tadej",middleName:null,surname:"Rojac",fullName:"Tadej Rojac",slug:"tadej-rojac"},{id:"111754",title:"Prof.",name:"Primoz",middleName:null,surname:"Segedin",fullName:"Primoz Segedin",slug:"primoz-segedin"}]},{id:"36167",title:"Application of Infrared Spectroscopy to Analysis of Chitosan/Clay Nanocomposites",slug:"application-of-infrared-spectroscopy-to-analysis-of-chitosan-clay-nanocomposites",signatures:"Suédina M.L. Silva, Carla R.C. Braga, Marcus V.L. Fook, Claudia M.O. Raposo, Laura H. Carvalho and Eduardo L. Canedo",authors:[{id:"104808",title:"Prof.",name:"Suedina Maria",middleName:"De Lima",surname:"Silva",fullName:"Suedina Maria Silva",slug:"suedina-maria-silva"},{id:"111910",title:"Prof.",name:"Carla",middleName:"Lima",surname:"R. C. Braga",fullName:"Carla R. C. Braga",slug:"carla-r.-c.-braga"},{id:"142933",title:"Prof.",name:"Marcus Vinícius",middleName:null,surname:"Lia Fook",fullName:"Marcus Vinícius Lia Fook",slug:"marcus-vinicius-lia-fook"},{id:"142934",title:"Prof.",name:"Claudia Maria",middleName:null,surname:"De Oliveira Raposo",fullName:"Claudia Maria De Oliveira Raposo",slug:"claudia-maria-de-oliveira-raposo"},{id:"142936",title:"Prof.",name:"Laura",middleName:null,surname:"Hecker De Carvalho",fullName:"Laura Hecker De Carvalho",slug:"laura-hecker-de-carvalho"},{id:"142939",title:"Dr.",name:"Eduardo Luis",middleName:null,surname:"Canedo",fullName:"Eduardo Luis Canedo",slug:"eduardo-luis-canedo"}]},{id:"36168",title:"Structural and Optical Behavior of Vanadate-Tellurate Glasses Containing PbO or Sm2O3",slug:"structural-and-optical-behavior-of-vanadate-tellurate-glasses",signatures:"E. Culea, S. Rada, M. Culea and M. Rada",authors:[{id:"114650",title:"Dr",name:"Eugen",middleName:null,surname:"Culea",fullName:"Eugen Culea",slug:"eugen-culea"},{id:"114653",title:"Dr.",name:"Simona",middleName:null,surname:"Rada",fullName:"Simona Rada",slug:"simona-rada"}]},{id:"36169",title:"Water in Rocks and Minerals - Species, Distributions, and Temperature Dependences",slug:"water-in-rocks-and-minerals-species-distributions-and-temperature-dependences",signatures:"Jun-ichi Fukuda",authors:[{id:"105384",title:"Dr.",name:"Jun-Ichi",middleName:null,surname:"Fukuda",fullName:"Jun-Ichi Fukuda",slug:"jun-ichi-fukuda"}]},{id:"36170",title:"Attenuated Total Reflection - Infrared Spectroscopy Applied to the Study of Mineral - Aqueous Electrolyte Solution Interfaces: A General Overview and a Case Study",slug:"attenuated-total-reflection-infrared-spectroscopy-applied-to-the-study-of-mineral-aqueous-el",signatures:"Grégory Lefèvre, Tajana Preočanin and Johannes Lützenkirchen",authors:[{id:"108416",title:"Dr.",name:"Johannes",middleName:null,surname:"Lützenkirchen",fullName:"Johannes Lützenkirchen",slug:"johannes-lutzenkirchen"},{id:"111675",title:"Dr.",name:"Gregory",middleName:null,surname:"Lefevre",fullName:"Gregory Lefevre",slug:"gregory-lefevre"},{id:"111676",title:"Prof.",name:"Tajana",middleName:null,surname:"Preocanin",fullName:"Tajana Preocanin",slug:"tajana-preocanin"}]},{id:"36171",title:"Research of Calcium Phosphates Using Fourier Transform Infrared Spectroscopy",slug:"research-of-calcium-phosphates-using-fourier-transformation-infrared-spectroscopy",signatures:"Liga Berzina-Cimdina and Natalija Borodajenko",authors:[{id:"110522",title:"Prof.",name:"Liga",middleName:null,surname:"Berzina-Cimdina",fullName:"Liga Berzina-Cimdina",slug:"liga-berzina-cimdina"},{id:"112181",title:"MSc.",name:"Natalija",middleName:null,surname:"Borodajenko",fullName:"Natalija Borodajenko",slug:"natalija-borodajenko"}]},{id:"36172",title:"FTIR Spectroscopy of Adsorbed Probe Molecules for Analyzing the Surface Properties of Supported Pt (Pd) Catalysts",slug:"ftir-spectroscopy-of-adsorbed-probe-molecules-for-analyzing-the-surface-properties-of-supported-pt-p",signatures:"Olga B. Belskaya, Irina G. Danilova, Maxim O. Kazakov, Roman M. Mironenko, Alexander V. Lavrenov and Vladimir A. Likholobov",authors:[{id:"107715",title:"Dr.",name:"Olga",middleName:null,surname:"Belskaya",fullName:"Olga Belskaya",slug:"olga-belskaya"},{id:"140198",title:"Dr.",name:"Irina",middleName:null,surname:"Danilova",fullName:"Irina Danilova",slug:"irina-danilova"},{id:"140200",title:"Dr.",name:"Maxim",middleName:null,surname:"Kazakov",fullName:"Maxim Kazakov",slug:"maxim-kazakov"},{id:"140202",title:"Mr.",name:"Roman",middleName:"Mikhailovich",surname:"Mironenko",fullName:"Roman Mironenko",slug:"roman-mironenko"},{id:"140203",title:"Dr.",name:"Alexander",middleName:null,surname:"Lavrenov",fullName:"Alexander Lavrenov",slug:"alexander-lavrenov"},{id:"140204",title:"Prof.",name:"Vladimir",middleName:null,surname:"Likholobov",fullName:"Vladimir Likholobov",slug:"vladimir-likholobov"}]},{id:"36173",title:"Hydrothermal Treatment of Hokkaido Peat - An Application of FTIR and 13C NMR Spectroscopy on Examining of Artificial Coalification Process and Development",slug:"hydrothermal-treatment-of-hokkaido-peat-an-application-of-ftir-and-13c-nmr-spectroscopy-on-examinin",signatures:"Anggoro Tri Mursito and Tsuyoshi Hirajima",authors:[{id:"104786",title:"Dr.",name:"Anggoro Tri",middleName:null,surname:"Mursito",fullName:"Anggoro Tri Mursito",slug:"anggoro-tri-mursito"},{id:"110978",title:"Prof.",name:"Tsuyoshi",middleName:null,surname:"Hirajima",fullName:"Tsuyoshi Hirajima",slug:"tsuyoshi-hirajima"}]},{id:"36174",title:"FTIR - An Essential Characterization Technique for Polymeric Materials",slug:"ftir-an-essential-characterization-technique-for-polymeric-materials",signatures:"Vladimir A. Escobar Barrios, José R. Rangel Méndez, Nancy V. Pérez Aguilar, Guillermo Andrade Espinosa and José L. Dávila Rodríguez",authors:[{id:"12709",title:"Dr.",name:"Jose Rene",middleName:null,surname:"Rangel-Mendez",fullName:"Jose Rene Rangel-Mendez",slug:"jose-rene-rangel-mendez"},{id:"12711",title:"Dr.",name:"Vladimir Alonso",middleName:null,surname:"Escobar Barrios",fullName:"Vladimir Alonso Escobar Barrios",slug:"vladimir-alonso-escobar-barrios"},{id:"112164",title:"Dr",name:"Guillermo",middleName:null,surname:"Andrade-Espinosa",fullName:"Guillermo Andrade-Espinosa",slug:"guillermo-andrade-espinosa"},{id:"112165",title:"Dr.",name:"José Luis",middleName:null,surname:"Dávila-Rodríguez",fullName:"José Luis Dávila-Rodríguez",slug:"jose-luis-davila-rodriguez"},{id:"112167",title:"Dr.",name:"Nancy Verónica",middleName:null,surname:"Pérez-Aguilar",fullName:"Nancy Verónica Pérez-Aguilar",slug:"nancy-veronica-perez-aguilar"}]},{id:"36175",title:"Preparation and Characterization of PVDF/PMMA/Graphene Polymer Blend Nanocomposites by Using ATR-FTIR Technique",slug:"preparation-and-characterization-of-pvdf-pmma-graphene-polymer-blend-nanocomposites-by-using-ft-ir-t",signatures:"Somayeh Mohamadi",authors:[{id:"108556",title:"Dr.",name:"Somayeh",middleName:null,surname:"Mohamadi",fullName:"Somayeh Mohamadi",slug:"somayeh-mohamadi"}]},{id:"36176",title:"Reflectance IR Spectroscopy",slug:"fundamental-of-reflectance-ir-spectroscopy",signatures:"Zahra Monsef Khoshhesab",authors:[{id:"111629",title:"Dr.",name:"Zahra",middleName:null,surname:"Monsef Khoshhesab",fullName:"Zahra Monsef Khoshhesab",slug:"zahra-monsef-khoshhesab"}]},{id:"36177",title:"Evaluation of Graft Copolymerization of Acrylic Monomers Onto Natural Polymers by Means Infrared Spectroscopy",slug:"evaluation-of-graft-copolymerization-of-acrylic-monomers-onto-natural-polymers-by-means-infrared-spe",signatures:"José Luis Rivera-Armenta, Cynthia Graciela Flores-Hernández, Ruth Zurisadai Del Angel-Aldana, Ana María Mendoza-Martínez, Carlos Velasco-Santos and Ana Laura Martínez-Hernández",authors:[{id:"37761",title:"Prof.",name:"Ana Laura",middleName:null,surname:"Martinez-Hernandez",fullName:"Ana Laura Martinez-Hernandez",slug:"ana-laura-martinez-hernandez"},{id:"107855",title:"Dr.",name:"Jose Luis",middleName:null,surname:"Rivera Armenta",fullName:"Jose Luis Rivera Armenta",slug:"jose-luis-rivera-armenta"},{id:"108894",title:"MSc.",name:"Cynthia Graciela",middleName:null,surname:"Flores-Hernández",fullName:"Cynthia Graciela Flores-Hernández",slug:"cynthia-graciela-flores-hernandez"},{id:"108896",title:"MSc.",name:"Ruth Zurisadai",middleName:null,surname:"Del Angel Aldana",fullName:"Ruth Zurisadai Del Angel Aldana",slug:"ruth-zurisadai-del-angel-aldana"},{id:"108898",title:"Dr.",name:"Carlos",middleName:null,surname:"Velasco-Santos",fullName:"Carlos Velasco-Santos",slug:"carlos-velasco-santos"},{id:"108905",title:"Dr.",name:"Ana Maria",middleName:null,surname:"Mendoza-Martínez",fullName:"Ana Maria Mendoza-Martínez",slug:"ana-maria-mendoza-martinez"}]},{id:"36178",title:"Applications of FTIR on Epoxy Resins - Identification, Monitoring the Curing Process, Phase Separation and Water Uptake",slug:"applications-of-ftir-on-epoxy-resins-identification-monitoring-the-curing-process-phase-separatio",signatures:"María González González, Juan Carlos Cabanelas and Juan Baselga",authors:[{id:"107857",title:"Prof.",name:"Juan",middleName:null,surname:"Baselga",fullName:"Juan Baselga",slug:"juan-baselga"},{id:"138113",title:"Dr.",name:"María",middleName:null,surname:"González",fullName:"María González",slug:"maria-gonzalez"},{id:"138114",title:"Dr.",name:"Juan C.",middleName:null,surname:"Cabanelas",fullName:"Juan C. Cabanelas",slug:"juan-c.-cabanelas"}]},{id:"36179",title:"Use of FTIR Analysis to Control the Self-Healing Functionality of Epoxy Resins",slug:"use-of-ft-ir-analysis-to-control-the-self-healing-functionality-of-epoxy-resins",signatures:"Liberata Guadagno and Marialuigia Raimondo",authors:[{id:"106836",title:"Prof.",name:"Liberata",middleName:null,surname:"Guadagno",fullName:"Liberata Guadagno",slug:"liberata-guadagno"}]},{id:"36180",title:"Infrared Analysis of Electrostatic Layer-By-Layer Polymer Membranes Having Characteristics of Heavy Metal Ion Desalination",slug:"infrared-analysis-of-electrostatic-layer-by-layer-polymer-membranes-having-characteristics-of-heavy",signatures:"Weimin Zhou, Huitan Fu and Takaomi Kobayashi",authors:[{id:"110384",title:"Dr.",name:"Takaomi",middleName:null,surname:"Kobayashi",fullName:"Takaomi Kobayashi",slug:"takaomi-kobayashi"}]},{id:"36181",title:"Infrared Spectroscopy as a Tool to Monitor Radiation Curing",slug:"infrared-spectroscopy-as-a-tool-to-monitor-radiation-curing",signatures:"Marco Sangermano, Patrick Meier and Spiros Tzavalas",authors:[{id:"112286",title:"Dr.",name:"Spiros",middleName:null,surname:"Tzavalas",fullName:"Spiros Tzavalas",slug:"spiros-tzavalas"},{id:"114382",title:"Prof.",name:"Marco",middleName:null,surname:"Sangermano",fullName:"Marco Sangermano",slug:"marco-sangermano"},{id:"114384",title:"Dr",name:"Patrick",middleName:null,surname:"Meier",fullName:"Patrick Meier",slug:"patrick-meier"}]},{id:"36182",title:"Characterization of Compositional Gradient Structure of Polymeric Materials by FTIR Technology",slug:"characterization-of-compositional-gradient-structure-of-polymeric-materials-by-ft-ir-technology",signatures:"Alata Hexig and Bayar Hexig",authors:[{id:"20867",title:"Dr.",name:"Bayar",middleName:null,surname:"Hexig",fullName:"Bayar Hexig",slug:"bayar-hexig"},{id:"111986",title:"Dr.",name:"Alata",middleName:null,surname:"Hexig",fullName:"Alata Hexig",slug:"alata-hexig"}]},{id:"36183",title:"Fourier Transform Infrared Spectroscopy - Useful Analytical Tool for Non-Destructive Analysis",slug:"fourier-trasform-infrared-spectroscopy-useful-analytical-tool-for-non-destructive-analysis",signatures:"Simona-Carmen Litescu, Eugenia D. Teodor, Georgiana-Ileana Truica, Andreia Tache and Gabriel-Lucian Radu",authors:[{id:"24425",title:"Dr.",name:"Simona Carmen",middleName:null,surname:"Litescu",fullName:"Simona Carmen Litescu",slug:"simona-carmen-litescu"},{id:"24429",title:"Prof.",name:"Gabriel-Lucian",middleName:null,surname:"Radu",fullName:"Gabriel-Lucian Radu",slug:"gabriel-lucian-radu"},{id:"108318",title:"Dr.",name:"Eugenia D.",middleName:null,surname:"Teodor",fullName:"Eugenia D. Teodor",slug:"eugenia-d.-teodor"},{id:"108323",title:"Dr.",name:"Georgiana-Ileana",middleName:null,surname:"Badea",fullName:"Georgiana-Ileana Badea",slug:"georgiana-ileana-badea"},{id:"136337",title:"Ms.",name:"Andreia",middleName:null,surname:"Tache",fullName:"Andreia Tache",slug:"andreia-tache"}]},{id:"36184",title:"Infrared Spectroscopy in the Analysis of Building and Construction Materials",slug:"infrared-spectroscopy-of-cementitious-materials",signatures:"Lucia Fernández-Carrasco, D. Torrens-Martín, L.M. Morales and Sagrario Martínez-Ramírez",authors:[{id:"107401",title:"Dr.",name:"Lucia J",middleName:null,surname:"Fernández",fullName:"Lucia J Fernández",slug:"lucia-j-fernandez"}]},{id:"36185",title:"Infrared Spectroscopy Techniques in the Characterization of SOFC Functional Ceramics",slug:"infrared-spectroscopy-techniques-in-the-characterization-of-sofc-functional-ceramics",signatures:"Daniel A. Macedo, Moisés R. Cesário, Graziele L. Souza, Beatriz Cela, Carlos A. Paskocimas, Antonio E. Martinelli, Dulce M. A. Melo and Rubens M. Nascimento",authors:[{id:"102015",title:"MSc.",name:"Daniel",middleName:null,surname:"Macedo",fullName:"Daniel Macedo",slug:"daniel-macedo"},{id:"112309",title:"MSc",name:"Moisés",middleName:"Romolos",surname:"Cesário",fullName:"Moisés Cesário",slug:"moises-cesario"},{id:"112310",title:"Ms.",name:"Graziele",middleName:null,surname:"Souza",fullName:"Graziele Souza",slug:"graziele-souza"},{id:"112311",title:"MSc.",name:"Beatriz",middleName:null,surname:"Cela",fullName:"Beatriz Cela",slug:"beatriz-cela"},{id:"112312",title:"Prof.",name:"Carlos",middleName:null,surname:"Paskocimas",fullName:"Carlos Paskocimas",slug:"carlos-paskocimas"},{id:"112314",title:"Prof.",name:"Antonio",middleName:null,surname:"Martinelli",fullName:"Antonio Martinelli",slug:"antonio-martinelli"},{id:"112315",title:"Prof.",name:"Dulce",middleName:null,surname:"Melo",fullName:"Dulce Melo",slug:"dulce-melo"},{id:"112316",title:"Dr.",name:"Rubens",middleName:"Maribondo Do",surname:"Nascimento",fullName:"Rubens Nascimento",slug:"rubens-nascimento"}]},{id:"36186",title:"Infrared Spectroscopy of Functionalized Magnetic Nanoparticles",slug:"infrared-spectroscopy-of-functionalized-magnetic-nanoparticles",signatures:"Perla E. García Casillas, Claudia A. Rodriguez Gonzalez and Carlos A. Martínez Pérez",authors:[{id:"104636",title:"Dr.",name:"Perla E.",middleName:null,surname:"García Casillas",fullName:"Perla E. García Casillas",slug:"perla-e.-garcia-casillas"},{id:"112440",title:"Dr.",name:"Carlos A.",middleName:null,surname:"Martínez Pérez",fullName:"Carlos A. Martínez Pérez",slug:"carlos-a.-martinez-perez"},{id:"112441",title:"Dr.",name:"Claudia A.",middleName:null,surname:"Rodriguez Gonzalez",fullName:"Claudia A. Rodriguez Gonzalez",slug:"claudia-a.-rodriguez-gonzalez"}]},{id:"36187",title:"Determination of Adsorption Characteristics of Volatile Organic Compounds Using Gas Phase FTIR Spectroscopy Flow Analysis",slug:"determination-of-adsorption-characteristics-of-volatile-organic-compounds-using-gas-phase-ftir-spect",signatures:"Tarik Chafik",authors:[{id:"107310",title:"Prof.",name:"Tarik",middleName:null,surname:"Chafik",fullName:"Tarik Chafik",slug:"tarik-chafik"}]},{id:"36188",title:"Identification of Rocket Motor Characteristics from Infrared Emission Spectra",slug:"identification-of-rocket-motor-characteristics-from-infrared-emission-spectra",signatures:"N. Hamp, J.H. Knoetze, C. Aldrich and C. Marais",authors:[{id:"112229",title:"Prof.",name:"Chris",middleName:null,surname:"Aldrich",fullName:"Chris Aldrich",slug:"chris-aldrich"},{id:"112232",title:"Prof.",name:"Hansie",middleName:null,surname:"Knoetze",fullName:"Hansie Knoetze",slug:"hansie-knoetze"},{id:"135327",title:"Ms.",name:"Corne",middleName:null,surname:"Marais",fullName:"Corne Marais",slug:"corne-marais"}]},{id:"36189",title:"Optical Technologies for Determination of Pesticide Residue",slug:"optical-technology-for-determination-of-pesticide-residue",signatures:"Yankun Peng, Yongyu Li and Jingjing Chen",authors:[{id:"113343",title:"Prof.",name:"Yankun",middleName:null,surname:"Peng",fullName:"Yankun Peng",slug:"yankun-peng"},{id:"116636",title:"Dr.",name:"Yongyu",middleName:null,surname:"Li",fullName:"Yongyu Li",slug:"yongyu-li"},{id:"116637",title:"Dr.",name:"Jingjing",middleName:null,surname:"Chen",fullName:"Jingjing Chen",slug:"jingjing-chen"}]},{id:"36190",title:"High Resolution Far Infrared Spectra of the Semiconductor Alloys Obtained Using the Synchrotron Radiation as Source",slug:"high-resolution-spectra-of-semiconductor-s-alloys-obtained-using-the-far-infrared-synchrotron-radi",signatures:"E.M. Sheregii",authors:[{id:"102655",title:"Prof.",name:"Eugen",middleName:null,surname:"Sheregii",fullName:"Eugen Sheregii",slug:"eugen-sheregii"}]},{id:"36191",title:"Effective Reaction Monitoring of Intermediates by ATR-IR Spectroscopy Utilizing Fibre Optic Probes",slug:"effective-reaction-monitoring-of-intermediates-by-atr-ir-spectroscopy-utilizing-fibre-optic-probes",signatures:"Daniel Lumpi and Christian Braunshier",authors:[{id:"109019",title:"Dr.",name:"Christian",middleName:null,surname:"Braunshier",fullName:"Christian Braunshier",slug:"christian-braunshier"},{id:"111798",title:"MSc.",name:"Daniel",middleName:null,surname:"Lumpi",fullName:"Daniel Lumpi",slug:"daniel-lumpi"}]}]}],publishedBooks:[{type:"book",id:"9239",title:"Digital Imaging",subtitle:null,isOpenForSubmission:!1,hash:"656ebe9652b39a1f5dc33d004170a1c4",slug:"digital-imaging",bookSignature:"Muhammad Sarfraz",coverURL:"https://cdn.intechopen.com/books/images_new/9239.jpg",editedByType:"Edited by",editors:[{id:"215610",title:"Prof.",name:"Muhammad",surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10991",title:"Digital Image Processing Applications",subtitle:null,isOpenForSubmission:!1,hash:"e7e57bea225c50ab5ac522627afc9d93",slug:"digital-image-processing-applications",bookSignature:"Paulo E. Ambrósio",coverURL:"https://cdn.intechopen.com/books/images_new/10991.jpg",editedByType:"Edited by",editors:[{id:"256064",title:"Dr.",name:"Paulo",surname:"Ambrosio",slug:"paulo-ambrosio",fullName:"Paulo Ambrosio"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7646",title:"Scientometrics Recent Advances",subtitle:null,isOpenForSubmission:!1,hash:"86bbdd04d7e80be14283d44969d1cc32",slug:"scientometrics-recent-advances",bookSignature:"Suad Kunosic and Enver Zerem",coverURL:"https://cdn.intechopen.com/books/images_new/7646.jpg",editedByType:"Edited by",editors:[{id:"88678",title:"Prof.",name:"Suad",surname:"Kunosic",slug:"suad-kunosic",fullName:"Suad Kunosic"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],publishedBooksByAuthor:[{type:"book",id:"10991",title:"Digital Image Processing Applications",subtitle:null,isOpenForSubmission:!1,hash:"e7e57bea225c50ab5ac522627afc9d93",slug:"digital-image-processing-applications",bookSignature:"Paulo E. Ambrósio",coverURL:"https://cdn.intechopen.com/books/images_new/10991.jpg",editedByType:"Edited by",editors:[{id:"256064",title:"Dr.",name:"Paulo",surname:"Ambrosio",slug:"paulo-ambrosio",fullName:"Paulo Ambrosio"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},onlineFirst:{chapter:{type:"chapter",id:"76735",title:"Anxiety, Coping Strategies and Resilience among Children and Adolescents during COVID-19 Pandemic: A Systematic Review",doi:"10.5772/intechopen.97828",slug:"anxiety-coping-strategies-and-resilience-among-children-and-adolescents-during-covid-19-pandemic-a-s",body:'
1. Introduction
As a result of danger, the brain responds with anxiety and anxiety behavior. In an evolutionary understanding, an anxiety reaction is aimed to avoid given threat. In fact, anxiety states may lead to adaptive behaviors, as the lack of given anxiety reaction in the event of a threat, e.g. a pandemic, could have negative consequences [1, 2]. The anxiety state and its aftermath can result desirable in numerous ways. One of them is escape or avoidance of danger, which increases the distance between the organism and the harmful factor. The anxiety state may trigger aggression towards the source of danger to neutralize it, or submissive behavior, resulting in the possibility of survival in life-threatening situations. An important factor in generating an anxiety reaction is the distance to the threat, what can be distinguished into immediate threat, perception of danger from a distance, and the presence of risk without a specific threat. Neuroimaging studies have shown activation of more archaic brain structures (such as the paraviductal gray matter) due to immediate threat, while at a greater distance to the danger, there was enhanced activation of the ventral prefrontal cortex. The variety of anxiety states occurring in humans is mainly related to the dynamic development of the prefrontal cortex [3].
2. Pandemic as a source of anxiety
The current crisis places multifaceted burden on children. The socio-ecological impact of the pandemic, which is understood to be enormous, must be also considered. The pandemic has affected children at different levels – health, social, family and individual [4]. COVID-19 worldwide crisis causes stress, worry and helplessness among children and adolescents. A role of sensitivity to anxiety in children was emphasized. However, it is still unclear whether the sensitivity to anxiety precedes or is a consequence of fear. It may be also a two-way relationship [5].
A risk factor for anxiety disorders in children is anxiety sensitivity. A meta-analysis found that anxiety sensitivity was associated with a higher level of anxiety [6]. The research results indicated so far a significant increase in the frequency of anxiety symptoms in children and adolescents due to the pandemics. Developmental mental health problems are associated with several risk factors. They affect more often children with special educational needs, those in poor general condition, whose parents have problems with mental health or who grow up in dysfunctional families.
The impact of COVID-19 pandemic and lockdown on children and youth depends on several vulnerability factors such as the developmental age, educational status, pre-existing mental health condition, being economically underprivileged or being quarantined due to infection/fear of infection [7, 8]. Children and adolescents may be more susceptible than other social groups to the psychosocial effects of pandemics, because they are in a critical period of development. Adolescence is a phase associated with increased risk for many psychiatric disorders, such as anxiety and depression [9]. Additionally, many of hormonal and neurobiological changes during adolescence correspond with heightened emotional reactivity and the ongoing process of incorporating coping strategies and stress regulation [10, 11]. Simultaneously, adolescence is marked by the increased importance of peer relationships and a greater reliance on peers for social support. The COVID-19 pandemic, especially for children and adolescents, will have a significant impact on their growth in terms of their whole life [12].
Resilience reflects processes and resources that restore equilibrium, offset challenges, and foster adaptation to harsh conditions. Research on individual adaptation to uncertain conditions during the pandemic requires longitudinal analyses, because factors connected with resilience will change dynamically over time.
As a result of COVID-19, children and adolescents have experienced unprecedented disruption of their daily lives. It is anticipated that this intermission may trigger mental illness, including anxiety. Many studies provided child and/or adolescent reports of anxiety during COVID-19 pandemic [13, 14, 15]. Chinese research found that 18.9% of children reported anxiety symptoms on the Screen for Child Anxiety Related Emotional Disorders [14]. Another study of prevalence of anxiety symptoms disclosed its frequency as 37.4% [15]. Parental reports according child and adolescents mental difficulties included anxiety symptoms as worry (28%), fear of death of a relative (22%) [16, 17].
The factors that generate anxiety include specific, characteristic personality traits of parents, especially their timidity. This applies to both parents, but more to the mother. Parents’ anxiety behavior is taken over by the child as a result of social learning through imitation, identification and replication of parental behaviors patterns. Among other factors triggering anxiety are also specific educational influences of parents and specific educational attitudes. The source of fear is the parental overprotective attitude, which can take two forms: over-indulgent care and domination-based care, or the attitude of excessive demands. A dysfunctional family has a negative impact on the development of all its members, especially children. The pandemic contributes to the exacerbation of dysfunctional family characteristics.
Anxiety is reduced by relationship with parents based on acceptance, love and care, when the child feels and knows that she/he is loved. Those children who have had too few of these situations acquire relatively permanent tendency to react with fear. Especially those, who had too little anxiety-relieving stimuli in early childhood. The emergence of anxiety is also related to temperamental traits. Children with anxiety traits are more likely to perceive the changes caused by a pandemic as a threat.
Social isolation is considered to be one of the most important psychological risk factors for the development of various diseases, including anxiety disorders. In single people, genes responsible for the production of inflammatory proteins were activated, while those related to fighting viral infection were inactive [18].
Studies in the UK, Europe, and Asia evidenced COVID-19 related anxiety and somatic symptoms in children. 20–50% children and adolescents were reported to experience worries about themselves, friends or family catching COVID-19, 8–10% children and young people had moderate to high somatic symptoms [13, 19, 20, 21]. Some research results indicated a significant increase in the level of anxiety (by 164%) in the self-assessment of health of children and young people during pandemic Covid-19 [22]. The researchers also reported that age, gender, knowledge about COVID-19, degree of worry about epidemiological infection, and confidence about overcoming the outbreak significantly influenced the children’s psychological status [23]. Studies also reported that girls showed higher anxiety levels during COVID-19 than male adolescents did. Some studies also reported that the anxiety levels among the adolescent population were significantly higher than those in children. In addition, adolescents in senior high school had the greatest anxiety symptoms [24]. Levita’s study showed that over 47% of girls and 60% of boys aged 13–18 had an anxiety increase above the cut-off point on the scale assessing the presence of anxiety [21]. Rates in European and Asian studies were lower, ranging between 10 and 30% [14, 15, 19]. Differences in anxiety have been established between European countries. Anxiety and depressive symptoms were more likely in children whose parents reported higher levels of stress [25]. Some studies showed that being female was a risk factor for higher rates of anxiety symptoms [15, 26], while other found that sex did not predict anxiety symptoms [14]. The financial strain predicted higher anxiety symptoms [17].
Perceived stress in parents and children was associated with negative coping strategies. Additionally, children’s stress levels were influenced by prior and current parental overreactivity. These results suggested that children in families with negative coping strategies and a history of parental overreactivity might be at risk for negative consequences of the lockdown [27]. Some families assumed that they are unable to cope with the multiple new challenges. They experienced a sense of chaos, inability to take decisions while focusing on negative information that aggravates panic. Other families looked for strategies to handle the difficulties. They moved on to mobilization stage and initiated all available coping resources.
Few studies have assessed protective factors. The awareness of COVID-19, together with pursuing interests, were protective against anxiety symptoms and helped in reducing child mental distress related to pandemic [15, 16]. Deterioration in mental state of minors caused by pandemics requires undertaking decisive protective measures- already now, during the ongoing limitations- as well as conducted in future long-term therapy. Worsening of children’s mental health status due to COVID-19 pandemics illuminates that age-specific coping strategies are crucial in response to distinct needs of young population.
3. Coping
3.1 Coping - background
Coping is substantial in considerations of how stressors affect children and adolescents as it emphasizes active role in the transactional process of dealing with stressful situations in a youngster’s life, but also brings reflections about one’s future development [28].
The understanding of coping in children and adolescents for many years relied on conceptualization of coping in adulthood defined by Lazarus and Folkman [29]. In this traditional approach coping is “constantly changing cognitive and behavioral efforts to manage specific external and/or internal demands that are appraised as taxing or exceeding the resources of the person” ([29], p. 141). It is understood as conscious cognitive and behavioral activity, aimed at reducing the intensity or duration of unpleasant feelings, preventing the occurrence and development of emotions or limiting the negative effects on their well-being. In the theory of psychological stress coping strategies can be categorized into problem-focused and emotion-focused [30]. Problem-focused forms of coping comprise of “aggressive interpersonal efforts to alter the situation, as well as cool, rational, deliberate efforts to problem solve, and emotion-focused forms of coping include distancing, self-controlling, seeking social support, escape-avoidance, accepting responsibility, and positive reappraisal ([30], p. 572). Folkman et al. [31] show possible ways of influencing health by the coping process: coping with stress can influence neurochemical reactions (their frequency, intensity, duration); coping with stress may be associated with engaging in anti-health behaviors; some forms of coping, such as denial or avoidance, may lead to maladaptive coping behaviors.
Slightly different approach towards coping assume that coping strategies can be considered as engaged and disengaged [32]. While engaged coping involves active confronting with stressors and reassuring thoughts, disengagement coping implicates passive reaction pattern, palliative response and avoidance. Empirical results clearly show that the first group of strategies is positively associated with more sense of control and psychological well-being [32].
When considering child and adolescent coping, the approach should be complemented by the developmental framework. Unquestionable is fact that coping strategies used by children depend on the age [28, 33]. Out of many ways of coping that have been identified in studies children and adolescents appear to favor: support seeking within the family, problem-solving (and instrumental action), escape, and, when escape is not possible, distraction. Young children use predominantly behavioral strategies to distract themselves (eg. playing with something fun), while older children use cognitive strategies (eg. thinking about something pleasant). Behavioral strategies of coping are common among children but normatively decrease in middle childhood. Preschool children mostly engage in: seeking social support (primarily from caregivers), intervening directly in stressful situations, withdrawing, avoidance, or using behavioral activities to distract attention. Due to progress of cognitive development, school children occur to rely on more varied coping strategies as they adjust cognition in problem-solving and distraction tactics, but also turn to sources of support outside family. In adolescence independency in thinking, ability to monitor one’s behavior and manage emotions by using positive self-talk and cognitive reformulation improve repertoire of coping strategies [28]. Over time anger-related emotion regulation decrease and media use as a way of managing stress increase [33]. Generally, children coping capacities develop in problem-solving strategy from instrumental action to planful problem-solving, in support-seeking from reliance on adults to more self-reliance. In distraction tactic behavior action gives way to cognition (with more organization, flexibility, integration with other coping strategies and aim specifically at problem) [34].
Not only age matters in understanding ability to cope with stress among children, but also gender. As the findings show [35] girls aged 8–13 tend to use more often maladaptive coping patterns than boys. Among young females as emotional regulating strategies (minimization and distraction/recreation) and problem-focused tactics (positive self-instructions) were decreased, while rumination, resignation and aggression were increased. Girls were also characterized by increase in engaging in the problem-focused strategy (support seeking) [35, 36]. The results of other study [37] indicated that active distraction used by girls decreased over time, while passive distraction increased. The paper referred also to boys who presented increase in self-destructive and aggressive coping behaviors increased with age.
Developmentally orientated researchers suggest that process of dealing with stress by children should comprise of such factors as emotion regulation, family functioning, temperament (and deriving from it reactivity) and the role of social interactions [28]. Researchers agree that positive coping lead to better psychological well-being and mental health [38, 39, 40].
3.2 Coping in children and adolescents in the context of COVID-19 pandemic
At this point, the literature on children’ coping strategies in the context of COVID-19 pandemic and its impact on children’ psychosocial well-being is still limited. The outcomes come mostly from observations, and research conducted in Europe and Asia.
Several studies have primarily examined coping strategies and factors associated according to age of children. Research conducted by Domínguez-Álvarez et al. [41] in a Spanish sample of children aged 3–12 during the acute phase of COVID-19 pandemic proved that children’s coping strategies differed between age groups and that stress management relied more on strategies reflecting engagement than disengagement. Parents of preschoolers, middle-aged children and early adolescents referred to child’s coping and possible observed changes on behavior related to the pre-pandemic functioning through specially developed scale. Comparing to older children, preschoolers appeared to use more strategies based on negative emotion regulation (such as yelling or getting angry). Children aged 7–9 were reported as using more engaged-oriented strategies such as problem solving, looking for understanding of such extraordinary circumstances and seeking instrumental social support. Early adolescents presented range of strategies of pandemic stress management and more complex ways of coping through positive emotion regulation (e.g., “trying to calm him/herself”), but also humor (“making jokes or trying to laugh about the current situation”) and wishful thinking (“wishing it never had happened”). Typically, engagement coping was positively correlated with psychosocial adjustment across all age groups. Disengagement-orientated coping was associated to some of the COVID-19-related stressors (i.e., close death, economic impact, and particularly fear of the future) and distinctively was related with negative outcomes (i.e., higher levels of behavioral and emotional difficulties) [41].
A study of Chinese adolescents aged 13–17 [42] revealed that general positive coping was protective factor for the occurrence of depressive, anxiety and stress. Additionally, positive coping was a protective factor for trauma-related distress in older adolescents. Negative coping occurred to be a risk factor for depression, anxiety, stress symptoms and trauma-related distress in a whole sample regardless of gender.
Available literature examining children and adolescents’ coping during COVID-19 pandemics focused also on the impact of adults from the environment of young people. Role of family and school in managing psychological distress among youngsters due to pandemics is being highlighted. Attention should be drawn to parents’ distress, parent–child relationships, the marital relationship in the family system, teachers’ distress, teacher–student relationships, and peer relationships within the school [43]. In one notable study [44] coping skills were investigated along with children’s adjustment. Results showed that maternal coping skills were protective factor with prediction for children’s positive emotions.
Accordingly to research findings, what helpful strategies in managing stress and anxiety can be provided by parents and specialists during the period of COVID-19 pandemics? Most studies report that attention should be paid to effective, sensitive, emotion-focused and empathetic communication concerning life-threatening illness as it assets children and other family members’ long-term psychological wellbeing [45].
Kang et al. [46] drew four main tactics for caregivers: Acknowledge, Discuss, Do, and Reflect. The first one refers to caregivers’ acknowledgement of the change and its possible consequences in order to ensure children that they can turn to their caregivers for support. Second strategy is based on supporting youngsters with accurate information from trustworthy sources tailored to their age and level of understanding aiming generally at better understanding of pandemics. Third tactic is associated with ensuring predictability in child’s environment, maintaining routines and – what seems to be crucial - equipping children with coping strategies (through expression of their feelings via writing and drawing, breathing exercises and progressive muscle relaxation, staying with touch with friends and schoolmates over social media platforms but with caregiver supervision). Finally, the fourth suggestion indicates caregivers’ affecting their psychological well-being [46].
Also De Young et al. [47] in their report described Australian parents’ efforts to support their children during early stages of COVID. They noticed that nearly 43% caregivers kept their child from seeing or hearing any information about COVID-19. 25% parents appeared to be a lot more cautious or overprotective with their child during the pandemic. Although many parents were found to relieve child of stress and anxiety through empathetic response to child’s emotion (94.3% of a research sample), maintenance or creating new routines (88.4%), staying in touch with family and friends (88.4%), managing emotion and thoughts by verbal communication (87.3%) and, finally, using practical coping strategies (78.5%). Positive parenting responses, including sticking to routines and showing empathy, correlated with more positive affect and emotion regulation in children and more positive parent–child relationships while taking care of daily habits was associated with less anxiety, depression and angry behaviors among youngsters.
As it was indicated, coping plays essential role for children and adolescents’ adjustment to stressors associated with COVID-19 pandemics such as uncertainty, social isolation, disruption in daily life routine, parents’ stress (such as working from home) [48].
When dealing with stress induced by the COVID-19 pandemic also resilience should be taken into account as it protects from future various psychiatric outcomes among young people.
4. Resilience
4.1 Resilience - background
In the last 20 years, there has been a growing interest in resilience theory. The first findings in this area were based on the long-term observation of people who suffered from schizophrenia. It was found that despite a difficult course of the disorder, some people’s abilities to cope are more adequate than the others [49]. These findings had an impact on broad research among children exposed to difficult developmental conditions [50]. As a result of amble evidence confirming negative consequences of trauma to mental development and mental health [51], there were attempts to find individual risk and protective factors which could differentiate the results of risk exposure [52]. Based on the findings, there were hopes for finding prevention and treatment methods to reduce psychopathology among those who experienced trauma [53]. Mental health’s researchers and practitioners are concerning not only with the effects of stressful or traumatic events but also the factors that determine the ability to restore physical equilibrium. Resilience is widely known as the ability to bounce back after facing up an extremely stressful situation or the ability to cope successfully with traumatic experiences. According to The American Psychological Association, resilience is defined as “the process of adapting well in the face of adversity, trauma, tragedy, threats or even significant sources of stress” [54]. It refers to individual processes and mechanisms. As far as such understanding of resilience is useful, it seems to be insufficient for understanding the complexity of the concept [49, 52, 53].
Considering resilience it is worth pointing out that nowadays it is not only referred to individual traits, abilities but also family and environmental factors. Despite being observed in one’s behavior, resilience is bound up with external issues. In the early 80ties, resilience was treated as characters strength and flexibility. This comprehension indicates resilience as the responsibility of the individual and omits the influence of family and social support which may be stigmatizing [55]. Being resilient is connected with a biological basis but it is also under the influence of the environment and can change during lifespan [52].
The major dimensions of resilience are risk and protective factors. Risk factors involve negative life experiences and nonadoptive traits. Protective factors involve individual traits, family and social support [1]. In the practical approach, there were found plenty of protective and risk factors which may be useful in planning proper psychological interventions. The major protective factors include individual traits: high self-esteem, sense of efficiency, sociability, intelligence, cheerful disposition, faith, talents, family factors: cohesion, compatibility, close relations between family members, good financial situation, external factors: safe neighborhood, having a mentor, belonging to a pro-social organization, attending an efficient school, features of society’s politics and culture - protection of the health and safety, care of the education system, prevention and protection against violence [56]. Risk factors are divided into specific and nonspecific. Nonspecific risk factors may lead to different disorders. Specific factors are strictly connected with a specific disorder. Commonly mentioned nonspecific factors include attention disorders, family conflicts, school failures, peer rejection, poverty, discrimination [55].
There are three major models of resilience: compensatory model, protective (or immunity) model and challenge model [55]. The compensatory model assumes that protective factors constrain the risk factors. The Protective (or immunity) model is based on the assumption that protective factors interact with risk factors and influence one’s behavior. Whereas the challenge model indicates that a medium level of risk factors make one more resistant to stress [57].
Resilience processes are activated in the face of adversity that cannot be controlled by the subject. As a result, resilience is considered in accidental cases such as war, disaster, illness [58].
4.2 Resilience in the light of COVID 19 pandemic
COVID 19 pandemic creates an extraordinary, demanding situation worldwide. It is named as a global health crisis and one of the greatest challenge in the medical, economic and social areas of our times. Despite being a global demand, pandemic COVID 19 concerns individuals. People had to face up with adversities as uncertainty and unpredictability that may lead to an increased level of stress. According to the previously mentioned thesis that people can differ considerably in terms of coping with adversities and numerous factors may modify the ability to deal with difficulties, resilience is an issue of growing interest in the light of pandemic COVID 19. Researchers are trying to identify factors that can play a protective role for mental health in the current situation [4].
There are a plethora of findings concerning the mental health of medical workers [4]. During the pandemic period, they are found to be exposed to stress factors to the great extent. However, as was mentioned above, pandemic related problems apply to every each of us. In China, it was found that adolescences are more likely to manifest depressive symptoms than adults during pandemic COVID- 19 [15]. The situation of children and adolescents in terms of a pandemic should be taken into consideration to a great extent.
Children and adolescents during the pandemic period have had to face up: isolation, remote learning, social distancing, limited contacts with peers, loneliness [15]. Those difficulties seem to be crucial in the children’s and adolescences because they are strictly connected with their basic needs and they also impairs the unspecific protective resilience factors. They are also exposed to the stress of their parents which may also influence the child’s mental health and his or her abilities to cope with stress.
Major research areas concerning the pandemic period applied to specific risk and protective resilience factors among children, the role of parents mental health condition on child resilience, possible interventions that may enhance resilience will be analyzed.
To find the risk and protective factors that may promote resilience, there were examined Hong-Kong families. The study group consists of children aged 2–12. Researchers assumed that family demographics, child psychosocial wellbeing, habits, parent–child interactions and parental stress will be crucial for resilience in the pandemic period. The research was based on the online survey completed by the parents based on their child’s observations. The risk factors that were found involves special educational needs of the child, chronic disease of a child, mental illness of mothers, one-parent family and low economic status of the family. Moreover, sleep difficulties, insufficient exercises, excessive use of electronic devices were connected with worse functioning of a child and higher level of parents stress. It is worth pointing out that, as it was proved, not only the child’s difficulties strictly connected with pandemic are tremendous but also the family situation and mental health of a parent before the emergence of COVID 19 [59].
Similarly to the previous findings, Fegert, Vitiello, Plener, Clemens suggested that the role of environmental (including family) and intrinsic stress-related processes are vital to predict the functioning of a child in the pandemic situation [60].
Daks, Peltz and Rogge focused on the parents’ traits and abilities as a resilience risk and protective factor. They found out that psychological flexibility versus inflexibility of a parent is a part of resiliency and can affluence the current pandemic situation. The 742 parents completed the online survey which measured the level of psychological flexibility. It was proved that the more flexible the parent is the better family cohesion is achieved. The lower flexibility of a parent can lead to disagreement in the family. In general, pandemic related circumstances increase the level of stress and the possible discord in the families. It was proved that the families with greater cohesion and greater psychological flexibility can cope with pandemic stressor more successfully than the families with lower psychological flexibility and, as a result, more family discords. There was also proved that the parents attitudes towards flexibility and results of particular attitude affluence the child’s level of stress. The research proved once again the role of parents traits, emotions and behavior on how resilient a child will be [57].
There are also suggestions that the younger the child is the more important role of protective resilience factors connected with a parent is. A developing child’s brain is more likely to be disturbed by stress factors. Moreover, young children’s executive functions and self-regulating skills are not developed to a great extent which could be also protective for them. The parents’ cognitive flexibility, stress coping strategies, mental health, positive parenting and attachment, warmth and sensitivity can be protective for a child. As far as the self-regulation skills of a child are immature, a parent should take over the function of the child’s emotion regulation by effective communication and emotional support. Despite the factors connected with a parent ability, the role of sport and creative activities were also pointed out as factors that can support the child in enhancing his and her abilities to cope with stress, regulate emotions and strengthen resilience [61].
On the other hand, resilience understood as the child’s trait was found to play a protective role for intrusive rumination during pandemic COVID 19. There was found a connection between creativity and intrusive rumination. The more creative children seem to be, the more intrusive rumination can create. However, it was found that resilience is a moderator between creativity and intrusive rumination. Highly developed resilience contributes to cognitive flexibility, positive thinking and, as a result, better adaptation [62].
There are plenty of findings that proved the negative effects of the pandemic. In contrary, there are also suggestions that self-isolation, remote learning may have also positive consequences that we should take advantage of. Dvorsky, Breaux and Becker extracted a specific situation, in which pandemic connected circumstances can be helpful for a child or adolescents. Remote learning was found to be helpful for children with educational problems in its traditional way. Online lessons provide a child possibility to individualize the way of learning. For instance, children with attention and behavior disorders have an opportunity to engage in activities that help them to overcome difficulties more likely than in schools. Those who suffer peer victimization have an opportunity to focus on learning and enhance selected, positive relations. Some children are also supposed to discover hobbies or talents more often. Moreover, the necessity to stay at home may provide an opportunity to bond up with family members as there are more chances to spent time together [63].
According to the researcher, resilience can be enhanced by mindfulness training and cognitive-behavioral techniques [64]. What is more, it was found that such training can also influence emotional intelligence defined as the ability to identify, understand the reason and the consequence of emotions and cope adaptively with them, Based on this assumption, Yonon tried to find the impact of mindfulness training on resilience during the pandemic period among middle schools. The Connor-Davidson Resilience Scale and Emotional Intelligence Scale were used. 180 students were examined. They were divided into the experimental and the control group. The Experimental Group participated in 8-weeks long Mindfulness Training. It was found that students from the experimental group enhanced significantly resilience as well as emotional intelligence. Mindfulness training was found to help to accept the present situation, avoid judgment and, as a result, avoid negative emotions [65].
Some practical guides devoted to resilience can be also found. Bartlett and Viverte on Childs Trends published: “Ways to Promote Children’s Resilience to the COVID-19 Pandemic”. The authors pointed out protective factors, presented as tips for a parent. They pointed out that sensitive, responsive caregiving, especially in the light of pandemic is an issue of paramount importance. There was suggested that not only a parent can meet this need but also adults who are not living with a child (grandparents, teachers). There is an importance of the usage of internet and electric devices to keep the contact. What is more, meeting basic needs is necessary. It is crucial for parenting to look for and benefit from the community services when it is needed. The third protective factor that was analyzed is emotional support for a child. Authors propose to take care of reassurance children about the love and support of a parent. It is worth keeping daily routines and practise with child regulation skills. In the guide, there was also indicated that support for caregivers is as important as support for a child. The mental health of a parent can be protective for the mental health of a child. The last suggestion is devoted to maintenance social contacts as far as it is possible using the internet. There were also pointed out the importance of conducting regular visits by professionals, social workers within families with violence abuse and poverty problem [66].
A parallel example of the open guide on how to enhance resilience during a pandemic was prepared by the Centre on the Developing Child, Harvard University. In this approach, researchers focus on the necessity to keep a balance between the negative and the positive outcomes related to pandemic. On the one hand, we should reduce the sources of stress, on the other – adjust supportive issues. It was indicated that the level of stress could be reduced by the social programs and organization promoting meet basic needs (food, healthcare, internet access), help in receiving financial support, encourage self-care for adults. Supportive issues that were mentioned concerns responsive relationships. Such relationships are commonly known as the relationship between a caregiver and a child but in this case, there is also a focus on a responsive relationship between an adult and adult. Responsive relationships have the potential to meet the needs of a person and relief stress. There was highlight the role of adults family and friendship relationships but also the contact with professional family workers and a parent. What is more, according to this guide, core skills such as executive function and self-regulation should be strengthened. These skills can be enhanced by basic activities such as day planning, creating checklists and prioritizing needs [67].
Centre for Childhood Resilience had also prepared tips that should be taken into consideration to promote resilience within children and their families. They also pay special attention to the role of caregivers on children during the pandemic period. Firstly, there was a focus on a safe environment for a child. As a safe environment physical and emotional support is understood. There was an assumption that the environment of a child is safe when it is explicable. Moreover, according to the tips, parents should support the child in emotional regulation. It is worth pointing out that the role of self-care of a parent is mentioned again. Additionally, the role of building relationships and connectedness with parents, siblings and remote family is highlighted [68].
Taking everything into account, resilience seems to be a crucial issue in the light of pandemic COVID-19. It was found to be vital to find factors that may affect children coping strategies. However, as far as it was concerned, parental care is an issue of paramount importance. There should be taken into consideration the supportive role of a parent on a child in detail. Moreover, a parent should also take care of his or her mental health to be able to take proper care of a child [57, 59, 60, 61, 66, 67, 68]. Additional factors that can be improved to enhance children’s and adolescents resilience during the pandemic mentioned above include: keeping relationships, reflecting optimistic approach, keeping a daily routine, practising mindfulness training and performing physical activities [59, 62, 65].
5. Conclusions and future directions
The COVID-19 pandemics seem to highlight the need for shaping effective means of coping with stress and anxiety and develop innovative strategies to improve the psychological well-being in young individuals. As review of the literature shows, caregivers “try to do their best”. However, consequences of anxiety, stress and violence exposure may be leading problems to meet in psychological and psychiatric care after pandemics. Taking into account that the way children and their parents response to pandemic stressors plays fundamental role for their adjustment, there is need of combining both child and family variables in tailored-preventive interventions targeted at enhancing resilience of children and their parents, reducing negative coping strategies, practicing effective means of coping with stress in order to protect their mental health now and in the future.
\n',keywords:"anxiety, resilience, COVID-19, children, adolescents, mental health, pandemic effects",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/76735.pdf",chapterXML:"https://mts.intechopen.com/source/xml/76735.xml",downloadPdfUrl:"/chapter/pdf-download/76735",previewPdfUrl:"/chapter/pdf-preview/76735",totalDownloads:441,totalViews:0,totalCrossrefCites:0,dateSubmitted:"February 17th 2021",dateReviewed:"April 22nd 2021",datePrePublished:"May 12th 2021",datePublished:"November 3rd 2021",dateFinished:"May 12th 2021",readingETA:"0",abstract:"COVID-19 pandemic is a global challenge that affects people’s mental health worldwide. Experiencing anxiety by children and adolescents, who are vulnerable to the impact of sustained stressors during developmentally sensitive periods, can lead to long-lasting effects on their health. The article brings insight into the short and long-term consequences of the COVID-19 pandemic on the children and adolescents’ mental health. The particular aim of this study is to investigate the relationship between anxiety, stress, and resilience in young individuals in the context of COVID-19. A review of the psychological effects of pandemic on children and adolescents was done using electronic databases. Most reviewed studies reported risk factors of psychosocial problems among children and adolescents during pandemics, resilience and positive coping as protective factors for the occurrence of anxiety and stress symptoms, and mediating role of parents’ stress impact on children’s behavioral and emotional problems. Clinical implications are discussed and additional research is suggested.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/76735",risUrl:"/chapter/ris/76735",signatures:"Malgorzata Dąbkowska, Anna Kobierecka-Dziamska and Monika Prusaczyk",book:{id:"10814",type:"book",title:"Anxiety, Uncertainty, and Resilience During the Pandemic Period",subtitle:"Anthropological and Psychological Perspectives",fullTitle:"Anxiety, Uncertainty, and Resilience During the Pandemic Period - Anthropological and Psychological Perspectives",slug:"anxiety-uncertainty-and-resilience-during-the-pandemic-period-anthropological-and-psychological-perspectives",publishedDate:"November 3rd 2021",bookSignature:"Fabio Gabrielli and Floriana Irtelli",coverURL:"https://cdn.intechopen.com/books/images_new/10814.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83968-126-4",printIsbn:"978-1-83968-119-6",pdfIsbn:"978-1-83968-215-5",isAvailableForWebshopOrdering:!0,editors:[{id:"259407",title:"Prof.",name:"Fabio",middleName:null,surname:"Gabrielli",slug:"fabio-gabrielli",fullName:"Fabio Gabrielli"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"48667",title:"Dr.",name:"Malgorzata",middleName:null,surname:"Dabkowska",fullName:"Malgorzata Dabkowska",slug:"malgorzata-dabkowska",email:"gosiadab@interia.pl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Nicolaus Copernicus University",institutionURL:null,country:{name:"Poland"}}},{id:"349165",title:"Dr.",name:"Anna",middleName:null,surname:"Kobierecka-Dziamska",fullName:"Anna Kobierecka-Dziamska",slug:"anna-kobierecka-dziamska",email:"akobierecka@op.pl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"349166",title:"Ms.",name:"Monika",middleName:null,surname:"Prusaczyk",fullName:"Monika Prusaczyk",slug:"monika-prusaczyk",email:"monika.anna.prusaczyk@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Pandemic as a source of anxiety",level:"1"},{id:"sec_3",title:"3. Coping",level:"1"},{id:"sec_3_2",title:"3.1 Coping - background",level:"2"},{id:"sec_4_2",title:"3.2 Coping in children and adolescents in the context of COVID-19 pandemic",level:"2"},{id:"sec_6",title:"4. Resilience",level:"1"},{id:"sec_6_2",title:"4.1 Resilience - background",level:"2"},{id:"sec_7_2",title:"4.2 Resilience in the light of COVID 19 pandemic",level:"2"},{id:"sec_9",title:"5. Conclusions and future directions",level:"1"}],chapterReferences:[{id:"B1",body:'Nesse RM, Williams GC. Evolution and healing: the new science of Darwinian medicine. London, Phoenix. 1996.'},{id:"B2",body:'Rybakowski J. Choroby psychiczne w świetle teorii ewolucji. Wszechświat. 2018; 119,1-3, 52-59.'},{id:"B3",body:'Mobbs D, Petrovic P, Marchant JL, Hassabis D, Weiskopf N, Seymour B, Dolan RJ, Frith CD. When fear is near: threat imminence elicits prefrontal-periaqueductal gray shifts in humans. Science. 2007; 24;317(5841):1079-83. DOI: 10.1126/science.1144298. PMID: 17717184'},{id:"B4",body:'Fegert JM, Vitiello B, Plener PL, Clemens V. Challenges and burden of the Coronavirus 2019 (COVID-19) pandemic for child and adolescent mental health: a narrative review to highlight clinical and research needs in the acute phase and the long return to normality. Child and Adolescent Psychiatry and Mental Health. 2020; 12;14:20. DOI: 10.1186/s13034-020-00329-3'},{id:"B5",body:'Waszczuk MA, Zavos HM, Eley TC. Genetic and environmental influences on relationship between anxiety sensitivity and anxiety subscales in children. Journal of Anxiety Disorders. 2013; 27(5):475-484. DOI: 10.1016/j.janxdis.2013.05.008'},{id:"B6",body:'Noël VA, Francis SE. A meta-analytic review of the role of child anxiety sensitivity in child anxiety. Journal of Abnormal Child Psychology. 2011; 39(5):721-733. DOI: 10.1007/s10802-011-9489-3.'},{id:"B7",body:'Singh S, Roy D, Sinha K, Parveen S, Sharma G, Joshi G. Impact of COVID-19 and lockdown on mental health of children and adolescents: A narrative review with recommendations. Psychiatry Research. 2020; 293 :113429. DOI: 10.1016/j.psychres.2020.113429'},{id:"B8",body:'Marques de Miranda D, da Silva Athanasio B, Sena Oliveira AC, Simoes-E-Silva AC. How is COVID-19 pandemic impacting mental health of children and adolescents?. International Journal of Disaster Risk Reduction. 2020; 51:101845. DOI: 10.1016/j.ijdrr.2020.101845'},{id:"B9",body:'Lee FS, Heimer H, Giedd JN, Lein ES, Šestan N, Weinberger DR, Casey BJ. Mental health. Adolescent mental health--opportunity and obligation. Science. 2014; 31;346(6209):547-9. DOI: 10.1126/science.1260497'},{id:"B10",body:'Ahmed SP, Bittencourt-Hewitt A, Sebastian CL. Neurocognitive bases of emotion regulation development in adolescence. Developmental Cognitive Neuroscience. 2015 Oct;15:11-25. DOI: 10.1016/j.dcn.2015.07.006.'},{id:"B11",body:'Spear L. The behavioral neuroscience of adolescence. New York: WW Norton & Company. 2010.'},{id:"B12",body:'Wade M, Prime H, Dillon T, Browne DT. Why we need longitudinal mental health research with children and youth during (and after) the COVID-19 pandemic. Psychiatry Research. 2020; 290: 113143. DOI: 10.1016/j.psychres.2020.113143'},{id:"B13",body:'Liu S, Liu Y, Liu Y. Somatic symptoms and concern regarding COVID-19 among Chinese college and primary school students: A cross-sectional survey. Psychiatry Research. 2020; 289,113070. DOI: 10.1016/j.psychres.2020.113070'},{id:"B14",body:'Xie X, Xue Q, Zhou Y, Zhu K, Liu Q, Zhang J, Song R. Mental Health Status Among Children in Home Confinement During the Coronavirus Disease 2019 Outbreak in Hubei Province, China. JAMA Pediatrics. 2020; 174(9):898-900. DOI: 10.1001/jamapediatrics.2020.1619'},{id:"B15",body:'Zhou SJ, Zhang LG, Wang LL, Guo ZC, Wang JQ, Chen JC, Liu M, Chen X, Chen JX. Prevalence and socio-demographic correlates of psychological health problems in Chinese adolescents during the outbreak of COVID-19. European Child & Adolescent Psychiatry. 2020; 29(6):749-758. DOI: 10.1007/s00787-020-01541-4'},{id:"B16",body:'Jiao WY, Wang LN, Liu J, Fang SF, Jiao FY, Pettoello-Mantovani M, Somekh E. Behavioral and Emotional Disorders in Children during the COVID-19 Epidemic. The journal of Pediatrics. 2020; 221:264-266.e1. DOI: 10.1016/j.jpeds.2020.03.013'},{id:"B17",body:'Rosen Z, Weinberger-Litman SL, Rosenzweig C, Rosmarin DH, Muennig P, Carmody ER, Rao ST, Litman L. Anxiety and distress among the first community quarantined in the U.S. due to COVID-19: psychological implications for the unfolding crisis. 2020; PsyArXiv. Preprint DOI: 10.31234/osf.io/7eq8c'},{id:"B18",body:'Kiecolt-Glaser JK, McGuire L, Robles TF, Glaser R. Psychoneuroimmunology and psychosomatic medicine: back to the future. Psychosomatic Medicine. 2002; 64(1):15-28. DOI: 10.1097/00006842-200201000-00004.'},{id:"B19",body:'Orgilés M, Morales A, Delvecchio E, Mazzeschi C, Espada JP (2020). Immediate psychological effects of the COVID-19 quarantine in youth from Italy and Spain. PsyArXiv. DOI: 10.31234/osf.io/5bpfz.'},{id:"B20",body:'Waite P, Creswell C (2020). Report 01: Findings from the first 1500 participants on parent/carer stress and child activity. Emerging Minds Co-Space Study. Available from: https://emergingminds.org.uk/wp-content/uploads/2020/04/Co-SPACE-initial-report-first 1500-participants-06-04-20.pdf [Accessed: 2021-03-01]'},{id:"B21",body:'Levita L. Initial research findings on the impact of COVID-19 on the well-being of young people aged 13 to 24 in the UK. COVID-19 psychological research consortium (C19PRC). 2020.'},{id:"B22",body:'Kooth. A Kooth data release: How has COVID-19 affected the mental health of children and young people in the United Kingdom? 2020. Available from: https://about.kooth.com/covid19-data/ [Accessed: 2021-02-28]'},{id:"B23",body:'Liu X, Luo W-T, Li Y, Li C-N, Hong Z-S, Chen H-L, Xiao F, Xia J-Y. Psychological status and behavior changes of the public during the COVID-19 epidemic in China. Infectious Diseases of Poverty. 2020;9:58. DOI: 10.1186/s40249-020-00678-3'},{id:"B24",body:'Meherali S, Punjani N, Louie-Poon S, Abdul Rahim K, Das JK, Salam RA, Lassi ZS. Mental Health of Children and Adolescents Amidst COVID-19 and Past Pandemics: A Rapid Systematic Review. International Journal of Environmental Research and Public Health. 2021; 18(7):3432. DOI: 10.3390/ijerph18073432'},{id:"B25",body:'Orgilés M, Espada JP, Delvecchio E, Francisco R, Mazzeschi C, Pedro M, Morales A. Anxiety and Depressive Symptoms in Children and Adolescents during COVID-19 Pandemic: A Transcultural Approach. Psicothema. 2021; 33(1):125-130. DOI: 10.7334/psicothema2020.287.'},{id:"B26",body:'Oosterhoff B, Palmer CA, Wilson J, Shook N. Adolescents\' Motivations to Engage in Social Distancing During the COVID-19 Pandemic: Associations With Mental and Social Health. Journal of Adolescent Health. 2020; 67(2):179-185. DOI: 10.1016/j.jadohealth.2020.05.004'},{id:"B27",body:'Achterberg M, Dobbelaar S, Boer OD, Crone EA. Perceived stress as mediator for longitudinal effects of the COVID-19 lockdown on wellbeing of parents and children. Scientific Reports. 2021; 3;11(1):2971. DOI: 10.1038/s41598-021-81720-8. PMID: 33536464; PMCID: PMC785920'},{id:"B28",body:'Skinner EA, Zimmer-Gembeck MJ. The development of coping. Annual Review of Psychology. 2007; 58: 119-144. DOI: 10.1146/annurev.psych.58.110405.085705'},{id:"B29",body:'Lazarus RS, Folkman S. Stress, appraisal, and coping. New York: Springer Publishing Company; 1984.'},{id:"B30",body:'Folkman S, Lazarus RS, Gruen RJ, DeLongis A. Appraisal, coping, health status, and psychological symptoms. 1986; 50(3):571-579. DOI: 10.1037//0022-3514.50.3.571'},{id:"B31",body:'Folkman S, Lazarus RS, et al. Dynamics of a stressful encounter: Cognitive appraisal, coping, and encounter outcomes. Journal of Personality and Social Psychology. 1986; 50(5): 992-1003.'},{id:"B32",body:'Dijkstra MT, Homan, AC. Engaging in Rather than Disengaging from Stress: Effective Coping and Perceived Control. Frontiers in Psychology. 2016; 7: 1415. DOI: 10.3389/fpsyg.2016.01415'},{id:"B33",body:'Eschenbeck H, Schmid S, Schröder I, Wasserfall N, Kohlmann, CW. Development of coping strategies from childhood to adolescence: Cross-sectional and longitudinal trends. European Journal of Health Psychology. 2018; 25(1), 18-30. DOI: 10.1027/2512-8442/a000005'},{id:"B34",body:'Zimmer-Gembeck M, Skinner EA. The development of coping across childhood and adolescence: an integrative review and critique of research. International Journal of Behavioral Development. 2011; 35.1: 1-17. DOI: 10.1177/0165025410384923'},{id:"B35",body:'Hampel P, Petermann F. Age and gender effects on coping in children and adolescents. Journal of Youth and Adolescence. 2005; 34.2: 73-83. DOI: 10.1007/s10964-005-3207-9'},{id:"B36",body:'Eschenbeck H, Carl-Walter K, Lohaus A. Gender Differences in Coping Strategies in Children and Adolescents. Journal of Individual Differences. 2007; 28:1, 18-26. DOI: 10.1027/1614-0001.28.1.18'},{id:"B37",body:'Grour MW, Thomas SP, Shoffner D. Adolescent stress and coping: A longitudinal study. Research in Nursing & Health. 1992;15.3: 209-217. DOI: 10.1002/nur.4770150307'},{id:"B38",body:'Bridges LJ. Coping as an element of developmental well-being. In: Bornstein MH, Davidson L, Keyes CLM, Moore KA, editors. Crosscurrents in contemporary psychology. Well-being: Positive development across the life course. Lawrence Erlbaum Associates Publishers; 2003; 155-166.'},{id:"B39",body:'Chao R Ch-L. Managing stress and maintaining well-being: Social support, problem-focused coping, and avoidant coping. Journal of Counseling & Development. 2011; 89.3: 338-348. DOI: 10.1002/j.1556-6678.2011.tb00098.x'},{id:"B40",body:'Mayordomo T, Viguer P, Sales A, Satorres E, Meléndez J. Resilience and Coping as Predictors of Well-Being in Adults. The Journal of Psychology. 2016; 150:7, 809-821, DOI: 10.1080/00223980.2016.1203276'},{id:"B41",body:'Domínguez-Álvarez B, López-Romero L, Isdahl-Troye A, Gómez-Fraguela JA, Romero E. Children Coping, Contextual Risk and Their Interplay During the COVID-19 Pandemic: A Spanish Case. Frontiers in psychology. 2020; 11: 3427. DOI: 10.3389/fpsyg.2020.577763'},{id:"B42",body:'Zhang C, Ye M, Fu Y, Yang M, Luo F, Yuan J, Tao Q. The psychological impact of the COVID-19 pandemic on teenagers in China. Journal of Adolescent Health. 2020; 67.6: 747-755. DOI: 10.1016/j.jadohealth.2020.08.026'},{id:"B43",body:'Zhou X. Managing psychological distress in children and adolescents following the COVID-19 epidemic: A cooperative approach. Psychological Trauma: Theory, Research, Practice, and Policy. 2020; 12(1), 76-78. DOI: 10.1037/tra0000754'},{id:"B44",body:'Petrocchi S, Levante A, Bianco F, Castelli I, Lecciso F. Maternal Distress/Coping and Children\'s Adaptive Behaviors During the COVID-19 Lockdown: Mediation Through Children\'s Emotional Experience. Frontiers in Public Health. 2020; 8:587833. DOI: 10.3389/fpubh.2020.587833'},{id:"B45",body:'Dalton L, Rapa E, Stein A. Protecting the psychological health of children through effective communication about COVID-19. The Lancet Child & Adolescent Health 2020; 4(5), 346-347. DOI: 10.1016/S2352-4642(20)30097-3'},{id:"B46",body:'Kang YQ, Lim TS, Ragen ES, Tan MY, Aishworiya R. Managing Children\'s Anxiety During COVID-19 Pandemic: Strategies for Providers and Caregivers. Frontiers in Psychiatry. 2020; 11:552823. DOI: 10.3389/fpsyt.2020.552823'},{id:"B47",body:'De Young, Paterson, March, Hoehn, Alisic, Cobham, Donovan, Middeldorp, Gash, Vasileva. COVID-19 Unmasked Young Children – Report 1: Early findings and recommendations Brisbane. Queensland Centre for Perinatal and Infant Mental Health, Children’s Health Queensland Hospital and Health Service. [Internet] 2020. Available from: https://www.childrens.health.qld.gov.au/wp-content/uploads/PDF/COVID-19/COVID19-Unmasked-Survey-Progress-Report-01.pdf [Accessed: 2021-03-01]'},{id:"B48",body:'de Figueiredo CS, Sandre PC, Portugal LCL, Mázala-de-Oliveira T, da Silva Chagas L, Raony Í, Bomfim POS. COVID-19 pandemic impact on children and adolescents\' mental health: Biological, environmental, and social factors. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2021; 106, 110171. DOI: 10.1016/j.pnpbp.2020.110171'},{id:"B49",body:'Borucka A, Ostaszewski K. Koncepcja resilience. Kluczowe pojęcia i wybrane zagadnienia. Medycyna Wieku Rozwojowego. 2008; 12: 587-597.'},{id:"B50",body:'Masten A.S, Powell J.L. A Resilience Framework for Research Policy and Practice. In: Luthar S.S, editor. Resilience and Vulnerability. Cambridge University Press. 2003. p. 1-28. DOI: 10.1017/CBO9780511615788.003'},{id:"B51",body:'Schore, A. N. Relational trauma and the developing right brain: The neurobiology of broken attachment bonds. InT.Baradon, editor. Relational trauma in infancy: Psychoanalytic, attachment and neuropsychological contributions to parent–infant psychotherapy. Routledge/Taylor & Francis Group. 2009; p. 19-47.'},{id:"B52",body:'Southwick, S. M, Bonanno, G. A, Masten, A. S, Panter-Brick C, Yehuda R. Resilience definitions, theory, and challenges: Interdisciplinary perspectives. European Journal of Psychotraumatology. 2014; 5. DOI: 10.3402/ejpt.v5.25338'},{id:"B53",body:'Masten A.S. Resilience in developing system: Progress and promise as the fourth waves rises. Development and Psychopathology. 200; 19: 921-930. DOI: 10.1017/S0954579407000442'},{id:"B54",body:'American Psychological Association. The road to resilience. Washington, DC: American Psychological Association. [Internet]. 2014. Available from: http://www.apa.org/helpcenter/road-resilience.aspx [Accessed: 2021-04-17]'},{id:"B55",body:'Garmezy N. Stres-Resistant Children: The Search for Protective Factors. In: Stevenson J, editor. Recent Research in Developmental Psychopathology. Pergamon Press: Oxford – New York – Toronto – Sydney – Paris – Frankfurt; 1985. p. 213-234.'},{id:"B56",body:'O’Dougherty Wright M, Masten A.S. Resilience processes in development. In: Goldstein S, Brooks R.B, editors. Fostering positive adaptation in the context of adversity, w: Hand Book of Resilience in Children. New York: Kluwer Academic; 2005. p. 17-38.'},{id:"B57",body:'Daks J.S, PeltzJ.S, Rogge R.D. Psychological flexibility and inflexibility as sources of resiliency and risk during a pandemic: Modeling the cascade of COVID-19 stress on family systems with a contextual behavioral science lens. Journal of Contextual Behavioural Science Empirical Research. 2021; 18: 16-27.'},{id:"B58",body:'Luthar S.S, Zigler E. Vulnerability and Competence: A Review of Research on Resilience in Childhood. Amer. J. Orthopsychiatry. 1991; 61: 6-22. DOI: 10.1037/h0079218'},{id:"B59",body:'Tso, W.W.Y, Wong, R.S, Tung, K.T.S. Vulnerability and resilience in children during the COVID-19 pandemic. Eur Child Adolesc Psychiatry. 2020; 291.DOI: 10.1007/s00787-020-01680-8'},{id:"B60",body:'Killgore W.D.S, Taylor E.C, Cloonan S.A, N.S. Dailey N.S. Psychological resilience during the COVID-19 lockdown. Psychiatry research. 2020; 291. DOI: 10.1016/j.psychres.2020.113216'},{id:"B61",body:'Urbanowicz A, Shankland R, McAloney-Kocman K. Coping in isolation: Predictors of individual and household risks and resilience against the COVID-19 pandemic. Social Sciences & Humanities Open. 2021; 3. DOI: 10.1016/j.ssaho.2021.100123'},{id:"B62",body:'Wang Q, Xin Zhao X,Yuming Yuan Y,Baoguo Shi.The Relationship Between Creativity and Intrusive Rumination Among Chinese Teenagers During the COVID-19 Pandemic: Emotional Resilience as a Moderator. Front Psychol. 2020; 11. DOI: 10.3389/fpsyg.2020.601104'},{id:"B63",body:'Dvorsky, M.R, Breaux R, Becker S.P. Finding ordinary magic in extraordinary times: child and adolescent resilience during the COVID-19 pandemic. Eur Child Adolesc Psychiatry. 2020. DOI: 10.1007/s00787-020-01583-8'},{id:"B64",body:'Joyce S, Shand F, Tighe J, Laurent S.J, Bryant R.A, Harvey S.B. Road to resilience: A systematic review and meta-analysis of resilience training programs and interventions. BMJ Open. 2018; 8. DOI: 10.1136/bmjopen-2017-017858'},{id:"B65",body:'Yuan Y. Mindfulness training on the resilience of adolescents under the COVID-19 epidemic: A latent growth curve analysis. Personality and Individual Differences. 2021; 172. DOI: 10.1016/j.paid.2020.110560'},{id:"B66",body:'Bartlet J.D., Viverte R. Child Trends. Ways to Promote Children’s Resilience to the COVID-19 Pandemic [Internet]. 2020. Available from: https://www.childtrends.org/publications/ways-to-promote-childrens-resilience-to-the-covid-19-pandemic [Accessed: 2021-04-17]'},{id:"B67",body:'Center on the Developing Child. Harvard University. How to Help Families and Staff Build Resilience During the COVID-19 Outbreak. [Internet]. 2020. Available from: https://developingchild.harvard.edu/resources/how-to-help-families-and-staff-build-resilience-during-the-covid-19-outbreak/ [Accessed: 2021-04-17]'},{id:"B68",body:'Center for Childhood Resilience. Promoting Resilient Families During COVID-19. [Internet]. 2020. Available from https://childhoodresilience.org/resources-1 [Accessed: 2021-04-17]'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Malgorzata Dąbkowska",address:"gosiadab@interia.pl",affiliation:'
Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, Poland
Antoni Jurasz University Hospital No. 1 in Bydgoszcz, Poland
'}],corrections:null},book:{id:"10814",type:"book",title:"Anxiety, Uncertainty, and Resilience During the Pandemic Period",subtitle:"Anthropological and Psychological Perspectives",fullTitle:"Anxiety, Uncertainty, and Resilience During the Pandemic Period - Anthropological and Psychological Perspectives",slug:"anxiety-uncertainty-and-resilience-during-the-pandemic-period-anthropological-and-psychological-perspectives",publishedDate:"November 3rd 2021",bookSignature:"Fabio Gabrielli and Floriana Irtelli",coverURL:"https://cdn.intechopen.com/books/images_new/10814.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83968-126-4",printIsbn:"978-1-83968-119-6",pdfIsbn:"978-1-83968-215-5",isAvailableForWebshopOrdering:!0,editors:[{id:"259407",title:"Prof.",name:"Fabio",middleName:null,surname:"Gabrielli",slug:"fabio-gabrielli",fullName:"Fabio Gabrielli"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},profile:{item:{id:"181159",title:"Mr.",name:"Patchamuthu",middleName:null,surname:"Ramasamy",email:"patchamuthu.ramasamy@qiup.edu.my",fullName:"Patchamuthu Ramasamy",slug:"patchamuthu-ramasamy",position:null,biography:null,institutionString:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",totalCites:0,totalChapterViews:"0",outsideEditionCount:0,totalAuthoredChapters:"1",totalEditedBooks:"0",personalWebsiteURL:null,twitterURL:null,linkedinURL:null,institution:null},booksEdited:[],chaptersAuthored:[{id:"49652",title:"Sample Preparations for Scanning Electron Microscopy – Life Sciences",slug:"sample-preparations-for-scanning-electron-microscopy-life-sciences",abstract:"Sample preparations are essential in scanning electron microscopy. Flawed sample preparations can undermine the quality of results and lead to false conclusions. Thus, the aim of this chapter is to equip researchers, post graduate students and technicians with essential knowledge required to prepare samples for scanning electron microscopy (SEM) investigations in the life sciences.",signatures:"Mogana Das Murtey and Patchamuthu Ramasamy",authors:[{id:"176330",title:"Dr.",name:"Mogana",surname:"Murtey",fullName:"Mogana Murtey",slug:"mogana-murtey",email:"moganbaadshah_071185@yahoo.com"},{id:"181159",title:"Mr.",name:"Patchamuthu",surname:"Ramasamy",fullName:"Patchamuthu Ramasamy",slug:"patchamuthu-ramasamy",email:"patchamuthu.ramasamy@qiup.edu.my"}],book:{id:"5075",title:"Modern Electron Microscopy in Physical and Life Sciences",slug:"modern-electron-microscopy-in-physical-and-life-sciences",productType:{id:"1",title:"Edited Volume"}}}],collaborators:[{id:"15744",title:"Dr.",name:"Milos",surname:"Janecek",slug:"milos-janecek",fullName:"Milos Janecek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/15744/images/4976_n.jpg",biography:"Miloš Janeček is a professor and researcher at the Charles University in Prague, Czech Republic. His expertize includes transmission and scanning electron microscopy and electron diffraction and analytical techniques of microstructure investigation and mechanical properties of light metals and alloys. He was a visiting research fellow at the University of Manitoba in Winnipeg, Canada, and at the INP Grenoble, France, and a visiting professor at the Technical University in Clausthal, Germany.\nHe has published more than 130 scientific papers in referred journals and about 50 conference papers and 2 book chapters. He graduated and obtained his PhD degree at the Charles University in Prague. Currently he is the head of the Department of Physics of Materials at the Faculty of Mathematics and Physics, Charles University in Prague. His current scientific interests include investigation of microstructure, mechanical and physical properties of ultrafine-grained materials processed by severe plastic deformation, and phase transformations in metastable Ti alloys. He is the member of the Editorial Board of Materials Science and Engineering and the TMS Ti International Committee.",institutionString:null,institution:null},{id:"176330",title:"Dr.",name:"Mogana",surname:"Murtey",slug:"mogana-murtey",fullName:"Mogana Murtey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/176330/images/8502_n.jpg",biography:"I am a scientist.",institutionString:null,institution:{name:"Universiti Sains Malaysia",institutionURL:null,country:{name:"Malaysia"}}},{id:"176343",title:"Dr.",name:"Diogo Benchimol",surname:"De Souza",slug:"diogo-benchimol-de-souza",fullName:"Diogo Benchimol De Souza",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rio de Janeiro State University",institutionURL:null,country:{name:"Brazil"}}},{id:"176436",title:"Prof.",name:"Bianca Martins",surname:"Gregório",slug:"bianca-martins-gregorio",fullName:"Bianca Martins Gregório",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"176437",title:"Prof.",name:"Fernanda Amorim De Morais",surname:"Nascimento",slug:"fernanda-amorim-de-morais-nascimento",fullName:"Fernanda Amorim De Morais Nascimento",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"177102",title:"Dr.",name:"Jitka",surname:"Stráská",slug:"jitka-straska",fullName:"Jitka Stráská",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"177103",title:"Dr.",name:"Josef",surname:"Strasky",slug:"josef-strasky",fullName:"Josef Strasky",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"177104",title:"Dr.",name:"Petr",surname:"Minarik",slug:"petr-minarik",fullName:"Petr Minarik",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"177105",title:"Dr.",name:"Robert",surname:"Kral",slug:"robert-kral",fullName:"Robert Kral",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:"Robert Král is an associate professor and researcher at the Charles University in Prague",institutionString:null,institution:null},{id:"177637",title:"Prof.",name:"Marlene",surname:"Benchimol",slug:"marlene-benchimol",fullName:"Marlene Benchimol",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null}]},generic:{page:{slug:"WIS-cost",title:"What Does It Cost?",intro:"
Open Access publishing helps remove barriers and allows everyone to access valuable information, but article and book processing charges also exclude talented authors and editors who can’t afford to pay. The goal of our Women in Science program is to charge zero APCs, so none of our authors or editors have to pay for publication.
",metaTitle:"What Does It Cost?",metaDescription:"Open Access publishing helps remove barriers and allows everyone to access valuable information, but article and book processing charges also exclude talented authors and editors who can’t afford to pay. The goal of our Women in Science program is to charge zero APCs, so none of our authors or editors have to pay for publication.",metaKeywords:null,canonicalURL:null,contentRaw:'[{"type":"htmlEditorComponent","content":"
We are currently in the process of collecting sponsorship. If you have any ideas or would like to help sponsor this ambitious program, we’d love to hear from you. Contact us at info@intechopen.com.
\\n\\n
All of our IntechOpen sponsors are in good company! The research in past IntechOpen books and chapters have been funded by:
\\n\\n
\\n\\t
European Commission
\\n\\t
Bill and Melinda Gates Foundation
\\n\\t
Wellcome Trust
\\n\\t
National Institute of Health (NIH)
\\n\\t
National Science Foundation (NSF)
\\n\\t
National Institute of Standards and Technology (NIST)
We are currently in the process of collecting sponsorship. If you have any ideas or would like to help sponsor this ambitious program, we’d love to hear from you. Contact us at info@intechopen.com.
\n\n
All of our IntechOpen sponsors are in good company! The research in past IntechOpen books and chapters have been funded by:
\n\n
\n\t
European Commission
\n\t
Bill and Melinda Gates Foundation
\n\t
Wellcome Trust
\n\t
National Institute of Health (NIH)
\n\t
National Science Foundation (NSF)
\n\t
National Institute of Standards and Technology (NIST)
\n\t
Research Councils United Kingdom (RCUK)
\n\t
Foundation for Science and Technology (FCT)
\n\t
Chinese Academy of Sciences
\n\t
Natural Science Foundation of China (NSFC)
\n\t
German Research Foundation (DFG)
\n\t
Max Planck Institute
\n\t
Austrian Science Fund (FWF)
\n\t
Australian Research Council (ARC)
\n
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"6700",title:"Dr.",name:"Abbass A.",middleName:null,surname:"Hashim",slug:"abbass-a.-hashim",fullName:"Abbass A. Hashim",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/6700/images/1864_n.jpg",biography:"Currently I am carrying out research in several areas of interest, mainly covering work on chemical and bio-sensors, semiconductor thin film device fabrication and characterisation.\nAt the moment I have very strong interest in radiation environmental pollution and bacteriology treatment. The teams of researchers are working very hard to bring novel results in this field. I am also a member of the team in charge for the supervision of Ph.D. students in the fields of development of silicon based planar waveguide sensor devices, study of inelastic electron tunnelling in planar tunnelling nanostructures for sensing applications and development of organotellurium(IV) compounds for semiconductor applications. I am a specialist in data analysis techniques and nanosurface structure. I have served as the editor for many books, been a member of the editorial board in science journals, have published many papers and hold many patents.",institutionString:null,institution:{name:"Sheffield Hallam University",country:{name:"United Kingdom"}}},{id:"54525",title:"Prof.",name:"Abdul Latif",middleName:null,surname:"Ahmad",slug:"abdul-latif-ahmad",fullName:"Abdul Latif Ahmad",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"20567",title:"Prof.",name:"Ado",middleName:null,surname:"Jorio",slug:"ado-jorio",fullName:"Ado Jorio",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universidade Federal de Minas Gerais",country:{name:"Brazil"}}},{id:"47940",title:"Dr.",name:"Alberto",middleName:null,surname:"Mantovani",slug:"alberto-mantovani",fullName:"Alberto Mantovani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"12392",title:"Mr.",name:"Alex",middleName:null,surname:"Lazinica",slug:"alex-lazinica",fullName:"Alex Lazinica",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/12392/images/7282_n.png",biography:"Alex Lazinica is the founder and CEO of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his PhD studies in Robotics at the Vienna University of Technology. Here he worked as a robotic researcher with the university's Intelligent Manufacturing Systems Group as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and most importantly he co-founded and built the International Journal of Advanced Robotic Systems- world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career, since it was a pathway to founding IntechOpen - Open Access publisher focused on addressing academic researchers needs. Alex is a personification of IntechOpen key values being trusted, open and entrepreneurial. Today his focus is on defining the growth and development strategy for the company.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"19816",title:"Prof.",name:"Alexander",middleName:null,surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/19816/images/1607_n.jpg",biography:"Alexander I. Kokorin: born: 1947, Moscow; DSc., PhD; Principal Research Fellow (Research Professor) of Department of Kinetics and Catalysis, N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow.\r\nArea of research interests: physical chemistry of complex-organized molecular and nanosized systems, including polymer-metal complexes; the surface of doped oxide semiconductors. He is an expert in structural, absorptive, catalytic and photocatalytic properties, in structural organization and dynamic features of ionic liquids, in magnetic interactions between paramagnetic centers. The author or co-author of 3 books, over 200 articles and reviews in scientific journals and books. He is an actual member of the International EPR/ESR Society, European Society on Quantum Solar Energy Conversion, Moscow House of Scientists, of the Board of Moscow Physical Society.",institutionString:null,institution:{name:"Semenov Institute of Chemical Physics",country:{name:"Russia"}}},{id:"62389",title:"PhD.",name:"Ali Demir",middleName:null,surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62389/images/3413_n.jpg",biography:"Dr. Ali Demir Sezer has a Ph.D. from Pharmaceutical Biotechnology at the Faculty of Pharmacy, University of Marmara (Turkey). He is the member of many Pharmaceutical Associations and acts as a reviewer of scientific journals and European projects under different research areas such as: drug delivery systems, nanotechnology and pharmaceutical biotechnology. Dr. Sezer is the author of many scientific publications in peer-reviewed journals and poster communications. Focus of his research activity is drug delivery, physico-chemical characterization and biological evaluation of biopolymers micro and nanoparticles as modified drug delivery system, and colloidal drug carriers (liposomes, nanoparticles etc.).",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"61051",title:"Prof.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"100762",title:"Prof.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"St David's Medical Center",country:{name:"United States of America"}}},{id:"107416",title:"Dr.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Texas Cardiac Arrhythmia",country:{name:"United States of America"}}},{id:"64434",title:"Dr.",name:"Angkoon",middleName:null,surname:"Phinyomark",slug:"angkoon-phinyomark",fullName:"Angkoon Phinyomark",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/64434/images/2619_n.jpg",biography:"My name is Angkoon Phinyomark. I received a B.Eng. degree in Computer Engineering with First Class Honors in 2008 from Prince of Songkla University, Songkhla, Thailand, where I received a Ph.D. degree in Electrical Engineering. My research interests are primarily in the area of biomedical signal processing and classification notably EMG (electromyography signal), EOG (electrooculography signal), and EEG (electroencephalography signal), image analysis notably breast cancer analysis and optical coherence tomography, and rehabilitation engineering. I became a student member of IEEE in 2008. During October 2011-March 2012, I had worked at School of Computer Science and Electronic Engineering, University of Essex, Colchester, Essex, United Kingdom. In addition, during a B.Eng. I had been a visiting research student at Faculty of Computer Science, University of Murcia, Murcia, Spain for three months.\n\nI have published over 40 papers during 5 years in refereed journals, books, and conference proceedings in the areas of electro-physiological signals processing and classification, notably EMG and EOG signals, fractal analysis, wavelet analysis, texture analysis, feature extraction and machine learning algorithms, and assistive and rehabilitative devices. I have several computer programming language certificates, i.e. Sun Certified Programmer for the Java 2 Platform 1.4 (SCJP), Microsoft Certified Professional Developer, Web Developer (MCPD), Microsoft Certified Technology Specialist, .NET Framework 2.0 Web (MCTS). I am a Reviewer for several refereed journals and international conferences, such as IEEE Transactions on Biomedical Engineering, IEEE Transactions on Industrial Electronics, Optic Letters, Measurement Science Review, and also a member of the International Advisory Committee for 2012 IEEE Business Engineering and Industrial Applications and 2012 IEEE Symposium on Business, Engineering and Industrial Applications.",institutionString:null,institution:{name:"Joseph Fourier University",country:{name:"France"}}},{id:"55578",title:"Dr.",name:"Antonio",middleName:null,surname:"Jurado-Navas",slug:"antonio-jurado-navas",fullName:"Antonio Jurado-Navas",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",biography:"Antonio Jurado-Navas received the M.S. degree (2002) and the Ph.D. degree (2009) in Telecommunication Engineering, both from the University of Málaga (Spain). He first worked as a consultant at Vodafone-Spain. From 2004 to 2011, he was a Research Assistant with the Communications Engineering Department at the University of Málaga. In 2011, he became an Assistant Professor in the same department. From 2012 to 2015, he was with Ericsson Spain, where he was working on geo-location\ntools for third generation mobile networks. Since 2015, he is a Marie-Curie fellow at the Denmark Technical University. His current research interests include the areas of mobile communication systems and channel modeling in addition to atmospheric optical communications, adaptive optics and statistics",institutionString:null,institution:{name:"University of Malaga",country:{name:"Spain"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:6597},{group:"region",caption:"Middle and South America",value:2,count:5902},{group:"region",caption:"Africa",value:3,count:2400},{group:"region",caption:"Asia",value:4,count:12537},{group:"region",caption:"Australia and Oceania",value:5,count:1006},{group:"region",caption:"Europe",value:6,count:17560}],offset:12,limit:12,total:132761},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{hasNoEditors:"1",sort:"dateEndThirdStepPublish",topicId:"7,10,15,24,5,6,8,9,11,23,14,16,17,12,18,19,20,21,22,13,25"},books:[{type:"book",id:"11254",title:"Optical Coherence Tomography",subtitle:null,isOpenForSubmission:!0,hash:"a958c09ceaab1fc44c1dd0a817f48c92",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11254.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11472",title:"21st Century Slavery",subtitle:null,isOpenForSubmission:!0,hash:"b341f3fc3411ced881e43ce007a892b8",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11472.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11473",title:"Social Inequality",subtitle:null,isOpenForSubmission:!0,hash:"20307129f7fb39aa443d5449acb6a784",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11473.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11546",title:"Smart and Sustainable Transportation",subtitle:null,isOpenForSubmission:!0,hash:"e8ea27a1ff85cde00efcb6f6968c20f8",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11546.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11554",title:"Information Systems Management",subtitle:null,isOpenForSubmission:!0,hash:"3134452ff2fdec020663f241c7a9a748",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11554.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11436",title:"Beauty",subtitle:null,isOpenForSubmission:!0,hash:"0e15ba86bab1a64f950318f3ab2584ed",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11436.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11438",title:"Fake News in the Era of Pandemics",subtitle:null,isOpenForSubmission:!0,hash:"bc9e4cab86c76f35cd70b39086d9b69e",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11438.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11588",title:"Autism",subtitle:null,isOpenForSubmission:!0,hash:"0c5043c6174db167599cb3f762e8bba8",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11588.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11605",title:"Bamboo",subtitle:null,isOpenForSubmission:!0,hash:"378d957561b27c86b750a9c7841a5d18",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11605.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11612",title:"Landraces",subtitle:null,isOpenForSubmission:!0,hash:"06316c41a6f6317ad2bee244dc98c6a4",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11612.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11616",title:"Foraging",subtitle:null,isOpenForSubmission:!0,hash:"955b60bb658c8d1a09dd4efc9bf6674b",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11616.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11632",title:"Updated Research on Bacteriophages",subtitle:null,isOpenForSubmission:!0,hash:"d34dfa0d5d10511184f97ddaeef9936b",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11632.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:43},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:12},{group:"topic",caption:"Business, Management and Economics",value:7,count:8},{group:"topic",caption:"Chemistry",value:8,count:19},{group:"topic",caption:"Computer and Information Science",value:9,count:18},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:18},{group:"topic",caption:"Engineering",value:11,count:47},{group:"topic",caption:"Environmental Sciences",value:12,count:7},{group:"topic",caption:"Immunology and Microbiology",value:13,count:12},{group:"topic",caption:"Materials Science",value:14,count:15},{group:"topic",caption:"Mathematics",value:15,count:7},{group:"topic",caption:"Medicine",value:16,count:109},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:2},{group:"topic",caption:"Neuroscience",value:18,count:7},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:11},{group:"topic",caption:"Physics",value:20,count:5},{group:"topic",caption:"Psychology",value:21,count:8},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:32},{group:"topic",caption:"Technology",value:24,count:1},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:2}],offset:12,limit:12,total:385},popularBooks:{featuredBooks:[],offset:0,limit:12,total:null},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[],latestBooks:[]},subject:{topic:{id:"1080",title:"Gynecologic Oncology",slug:"medicine-oncology-gynecologic-oncology",parent:{id:"190",title:"Oncology",slug:"medicine-oncology"},numberOfBooks:5,numberOfSeries:0,numberOfAuthorsAndEditors:131,numberOfWosCitations:31,numberOfCrossrefCitations:32,numberOfDimensionsCitations:64,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"1080",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"9168",title:"Gynaecological Malignancies",subtitle:"Updates and Advances",isOpenForSubmission:!1,hash:"aca886add99b871e9c31fb78dc3dbb9e",slug:"gynaecological-malignancies-updates-and-advances",bookSignature:"Gwo Yaw Ho and Sophia Frentzas",coverURL:"https://cdn.intechopen.com/books/images_new/9168.jpg",editedByType:"Edited by",editors:[{id:"297757",title:null,name:"Gwo-Yaw",middleName:null,surname:"Ho",slug:"gwo-yaw-ho",fullName:"Gwo-Yaw Ho"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7271",title:"Cancer Metastasis",subtitle:null,isOpenForSubmission:!1,hash:"365bb4cd3b255b91815abb7fed5eda01",slug:"cancer-metastasis",bookSignature:"Yasemin Basbinar and Gizem Calıbası-Kocal",coverURL:"https://cdn.intechopen.com/books/images_new/7271.jpg",editedByType:"Edited by",editors:[{id:"242097",title:"Dr.",name:"Yasemin",middleName:null,surname:"Basbinar",slug:"yasemin-basbinar",fullName:"Yasemin Basbinar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5997",title:"Ovarian Cancer",subtitle:"From Pathogenesis to Treatment",isOpenForSubmission:!1,hash:"0dfe8201654bd8415c0fe89ebaafdfa8",slug:"ovarian-cancer-from-pathogenesis-to-treatment",bookSignature:"Omer Devaja and Andreas Papadopoulos",coverURL:"https://cdn.intechopen.com/books/images_new/5997.jpg",editedByType:"Edited by",editors:[{id:"129074",title:"Dr.",name:"Omer",middleName:null,surname:"Devaja",slug:"omer-devaja",fullName:"Omer Devaja"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6421",title:"Cervical Cancer",subtitle:"Screening, Treatment and Prevention - Universal Protocols for Ultimate Control",isOpenForSubmission:!1,hash:"33de90dc3727148b27fc60f4e46f92eb",slug:"cervical-cancer-screening-treatment-and-prevention-universal-protocols-for-ultimate-control",bookSignature:"Rajamanickam Rajkumar",coverURL:"https://cdn.intechopen.com/books/images_new/6421.jpg",editedByType:"Edited by",editors:[{id:"120109",title:"Dr.",name:"Rajamanickam",middleName:null,surname:"Rajkumar",slug:"rajamanickam-rajkumar",fullName:"Rajamanickam Rajkumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"712",title:"Intraepithelial Neoplasia",subtitle:null,isOpenForSubmission:!1,hash:"a1aa9858b1db54a89329fa086261dfd2",slug:"intraepithelial-neoplasia",bookSignature:"Supriya Srivastava",coverURL:"https://cdn.intechopen.com/books/images_new/712.jpg",editedByType:"Edited by",editors:[{id:"85273",title:"Dr.",name:"Supriya",middleName:null,surname:"Srivastava",slug:"supriya-srivastava",fullName:"Supriya Srivastava"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:5,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"58601",doi:"10.5772/intechopen.72705",title:"Ovarian Cancer Genetics: Subtypes and Risk Factors",slug:"ovarian-cancer-genetics-subtypes-and-risk-factors",totalDownloads:2481,totalCrossrefCites:8,totalDimensionsCites:10,abstract:"The genetics of ovarian cancer are a complex, ever evolving concept that presents hurdles in classification, diagnosis, and treatment in the clinic. Instead of common driver mutations, genomic instability is one of the hallmarks of ovarian cancer. While ovarian cancer is stratified into different clinical subtypes, there still exists extensive genetic and progressive diversity within each subtype. In high-grade serous ovarian cancer, the most common subtype, TP53 is mutated in over 90% of all patients while the next most common mutation is less than 20%. However, next-generation sequencing and biological statistics have shown that mutations within DNA repair pathways, including BRCA1 and BRCA2, are common in about 50% of all high-grade serous patients leading to the development of a breakthrough therapy of poly ADP ribose polymerase (PARP) inhibitors. This is just one example of how a better understanding of the complex genetic background of ovarian cancer can improve clinical treatment. A thorough review of ovarian cancer genetics and the effect it has on disease development, diagnosis, progression, and treatment will enhance the understanding of how to better research and treat ovarian cancer.",book:{id:"5997",slug:"ovarian-cancer-from-pathogenesis-to-treatment",title:"Ovarian Cancer",fullTitle:"Ovarian Cancer - From Pathogenesis to Treatment"},signatures:"Jeff Hirst, Jennifer Crow and Andrew Godwin",authors:[{id:"219865",title:"Dr.",name:"Jeff",middleName:null,surname:"Hirst",slug:"jeff-hirst",fullName:"Jeff Hirst"},{id:"219866",title:"Dr.",name:"Andrew",middleName:null,surname:"Godwin",slug:"andrew-godwin",fullName:"Andrew Godwin"},{id:"219867",title:"Dr.",name:"Jennifer",middleName:null,surname:"Crow",slug:"jennifer-crow",fullName:"Jennifer Crow"}]},{id:"60255",doi:"10.5772/intechopen.75484",title:"The Role of Circulating Biomarkers in the Early Diagnosis of Ovarian Cancer",slug:"the-role-of-circulating-biomarkers-in-the-early-diagnosis-of-ovarian-cancer",totalDownloads:1199,totalCrossrefCites:3,totalDimensionsCites:5,abstract:"Ovarian cancer is the leading cause of gynecologic-related cancer death and epithelial ovarian cancer (EOC) is the most lethal sub-type. EOC is usually asymptomatic, and few screening tests are available. Diagnosis of ovarian cancer can be difficult because of the nonspecific symptoms. Despite the various diagnostic methods used, there is no reliable early diagnostic test and it needs to be developed. Specific biomarkers may have potential with the least possible invasive procedure. Biomarkers with a high sensitivity to ovarian cancer should be identified. Circulating biomarkers that are significant tools for non-invasive early diagnosis can be analyzed using circulating tumor cells, exosomes, and circulating nucleic acids. Protein, gene, metabolite, and miRNA-based biomarkers can be used for ovarian cancer diagnosis. As non-coding RNAs, MiRNAs may have an important role in ovarian cancer diagnosis due to their effects on mRNA expression levels. The most recent developments regarding the potential of circulating biomarkers to detect early ovarian cancer is presented in this chapter.",book:{id:"5997",slug:"ovarian-cancer-from-pathogenesis-to-treatment",title:"Ovarian Cancer",fullTitle:"Ovarian Cancer - From Pathogenesis to Treatment"},signatures:"Ece Gumusoglu and Tuba Gunel",authors:[{id:"68399",title:"Dr.",name:"Tuba",middleName:null,surname:"Gunel",slug:"tuba-gunel",fullName:"Tuba Gunel"},{id:"202504",title:"M.Sc.",name:"Ece",middleName:null,surname:"Gumusoglu",slug:"ece-gumusoglu",fullName:"Ece Gumusoglu"}]},{id:"61944",doi:"10.5772/intechopen.78383",title:"The Landscape of Histone Modification in Cancer Metastasis",slug:"the-landscape-of-histone-modification-in-cancer-metastasis",totalDownloads:1543,totalCrossrefCites:1,totalDimensionsCites:4,abstract:"Metastasis represents one of the most devastating aspects of cancer. Epithelial to mesenchymal transition (EMT) has been shown to play a critical role in tumorigenic metastasis. During metastatic progression, both genetic and epigenetic modifications endow cancer cells with properties that modulate the capacity for metastatic success. Histone modification is profoundly altered in cancer cells and contributes to cancer metastasis by controlling different metastatic phenotypes. Here, we first review histone modifications and discuss their roles in EMT and metastasis, with a particular focus on histone methylation and acetylation. Second, we review the major histone modification enzymes that control chromatin in cancer metastasis. Third, we discuss the transcriptional regulation concerted by these enzymes with EMT transcription factors at different molecular layers. Finally, we discuss pharmacologic manipulation of histone modification enzymes for metastasis treatment. A comprehensive understanding of histone modification in metastasis will not only provide new insights into our knowledge of cancer progression and metastasis, but also offer a novel approach for the development of innovative therapeutic strategies.",book:{id:"7271",slug:"cancer-metastasis",title:"Cancer Metastasis",fullTitle:"Cancer Metastasis"},signatures:"Zhaoping Qiu, Jianlin Wang and Yadi Wu",authors:[{id:"121037",title:"Dr.",name:"Yadi",middleName:null,surname:"Wu",slug:"yadi-wu",fullName:"Yadi Wu"},{id:"256631",title:"Dr.",name:"Zhaoping",middleName:null,surname:"Qiu",slug:"zhaoping-qiu",fullName:"Zhaoping Qiu"},{id:"256632",title:"Dr.",name:"Jianlin",middleName:null,surname:"Wang",slug:"jianlin-wang",fullName:"Jianlin Wang"}]},{id:"62124",doi:"10.5772/intechopen.78717",title:"Epithelial-Mesenchymal Transition in Tumor Microenvironment Induced by Hypoxia",slug:"epithelial-mesenchymal-transition-in-tumor-microenvironment-induced-by-hypoxia",totalDownloads:1572,totalCrossrefCites:2,totalDimensionsCites:4,abstract:"A tumor microenvironment contains various noncancerous cells including adipocytes, fibroblasts, immune and inflammatory cells, neuroendocrine cells, pericytes, vascular and lymphatic endothelial cells, and the extracellular matrix that surrounds cancerous cells. In the tumor microenvironment, cancer cells interact and cross talk with noncancerous cells and orchestrate different mechanisms of cancer such as tumorigenesis, angiogenesis, and metastasis. Moreover, the expansive nature of cancer cells and chaotic angiogenesis affect microcirculation as well as alter the oxygen concentration progressively. Hypoxia, a key player in the multistep process of cancer metastasis, is important in different regions of the tumor microenvironment. Hypoxia may transform cancer cells to become more aggressive and invasive by triggering overexpression of several hypoxia-related factors that activate epithelial-mesenchymal transition (EMT). Herein, the current knowledge of how hypoxia-driven EMT is presented in the tumor microenvironment of solid cancers is discussed.",book:{id:"7271",slug:"cancer-metastasis",title:"Cancer Metastasis",fullTitle:"Cancer Metastasis"},signatures:"Görkem Eskiizmir and Erdoğan Özgür",authors:[{id:"247860",title:"Dr.",name:"Gorkem",middleName:null,surname:"Eskiizmir",slug:"gorkem-eskiizmir",fullName:"Gorkem Eskiizmir"},{id:"247862",title:"Dr.",name:"Erdogan",middleName:null,surname:"Özgür",slug:"erdogan-ozgur",fullName:"Erdogan Özgür"}]},{id:"59258",doi:"10.5772/intechopen.73863",title:"Ovarian Cancer Overview: Molecular Biology and Its Potential Clinical Application",slug:"ovarian-cancer-overview-molecular-biology-and-its-potential-clinical-application",totalDownloads:1320,totalCrossrefCites:1,totalDimensionsCites:4,abstract:"Over the previous two decades, there has been a shift in the ovarian cancer paradigm to consider it as a multiplicity of disease types rather than a single disease, requiring specialized medical management from molecular diagnosis through to treatment. Despite the achieved improvements in diagnosis, surgery, and systemic treatment, ovarian cancer remains the leading cause of death from gynecological tumors in western countries. The study of ovarian cancer at a molecular level could reveal potential biomarkers of disease diagnosis and progression, as well as possible therapeutic targets in areas such as angiogenesis and homologous recombination deficiencies. Although this area of research is proving invaluable concerning newer therapeutic approaches, platinum-based chemotherapy continues to be the core of the first-line treatment. Genomic screening focusing on the identification of prognostic and predictive markers is considered one of the leading areas for future ovarian cancer research.",book:{id:"5997",slug:"ovarian-cancer-from-pathogenesis-to-treatment",title:"Ovarian Cancer",fullTitle:"Ovarian Cancer - From Pathogenesis to Treatment"},signatures:"Joana Assis, Deolinda Pereira, Augusto Nogueira and Rui Medeiros",authors:[{id:"50776",title:"Prof.",name:"Rui Manuel",middleName:null,surname:"de Medeiros Melo Silva",slug:"rui-manuel-de-medeiros-melo-silva",fullName:"Rui Manuel de Medeiros Melo Silva"},{id:"57116",title:"MSc.",name:"Augusto",middleName:null,surname:"Nogueira",slug:"augusto-nogueira",fullName:"Augusto Nogueira"},{id:"209193",title:"MSc.",name:"Joana",middleName:null,surname:"Assis",slug:"joana-assis",fullName:"Joana Assis"},{id:"209194",title:"MSc.",name:"Deolinda",middleName:null,surname:"Pereira",slug:"deolinda-pereira",fullName:"Deolinda Pereira"}]}],mostDownloadedChaptersLast30Days:[{id:"57832",title:"Secondary Prevention of Uterine Cervical Cancer",slug:"secondary-prevention-of-uterine-cervical-cancer",totalDownloads:1097,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Secondary prevention by cervical cytology has clearly improved the mortality rate of uterine cervical cancer (CC) by enabling early detection and treatment of high-grade squamous intraepithelial lesion (HSIL) or cervical intraepithelial neoplasia (CIN), which is a precancerous lesion. In the past two decades, HPV-DNA testing, including HPV typing, has clearly brought about positive effects on secondary prevention of CC. However, in practice, CC remains a fatal disease and is the second leading cause of cancer deaths in women aged 20–39 years. Although elucidation of the mechanisms of HPV carcinogenesis and development of a prophylactic vaccine have made CC a preventable disease, eradication of CC is expected to take several decades. Therefore, primary screening to decrease the mortality rate of CC will remain important for a while. In addition, the clinical application of simple biomarkers to stratify HPV-positive women is important for maintenance of medical economy and avoidance of overtreatment in women in the reproductive age. Therefore, the development of an inexpensive therapy or vaccine that can be used worldwide is necessary to overcome cancer deaths due to CC.",book:{id:"6421",slug:"cervical-cancer-screening-treatment-and-prevention-universal-protocols-for-ultimate-control",title:"Cervical Cancer",fullTitle:"Cervical Cancer - Screening, Treatment and Prevention - Universal Protocols for Ultimate Control"},signatures:"Seiya Sato and Hiroaki Itamochi",authors:[{id:"217868",title:"Prof.",name:"Hiroaki",middleName:null,surname:"Itamochi",slug:"hiroaki-itamochi",fullName:"Hiroaki Itamochi"},{id:"231820",title:"Dr.",name:"Seiya",middleName:null,surname:"Sato",slug:"seiya-sato",fullName:"Seiya Sato"}]},{id:"58601",title:"Ovarian Cancer Genetics: Subtypes and Risk Factors",slug:"ovarian-cancer-genetics-subtypes-and-risk-factors",totalDownloads:2481,totalCrossrefCites:8,totalDimensionsCites:10,abstract:"The genetics of ovarian cancer are a complex, ever evolving concept that presents hurdles in classification, diagnosis, and treatment in the clinic. Instead of common driver mutations, genomic instability is one of the hallmarks of ovarian cancer. While ovarian cancer is stratified into different clinical subtypes, there still exists extensive genetic and progressive diversity within each subtype. In high-grade serous ovarian cancer, the most common subtype, TP53 is mutated in over 90% of all patients while the next most common mutation is less than 20%. However, next-generation sequencing and biological statistics have shown that mutations within DNA repair pathways, including BRCA1 and BRCA2, are common in about 50% of all high-grade serous patients leading to the development of a breakthrough therapy of poly ADP ribose polymerase (PARP) inhibitors. This is just one example of how a better understanding of the complex genetic background of ovarian cancer can improve clinical treatment. A thorough review of ovarian cancer genetics and the effect it has on disease development, diagnosis, progression, and treatment will enhance the understanding of how to better research and treat ovarian cancer.",book:{id:"5997",slug:"ovarian-cancer-from-pathogenesis-to-treatment",title:"Ovarian Cancer",fullTitle:"Ovarian Cancer - From Pathogenesis to Treatment"},signatures:"Jeff Hirst, Jennifer Crow and Andrew Godwin",authors:[{id:"219865",title:"Dr.",name:"Jeff",middleName:null,surname:"Hirst",slug:"jeff-hirst",fullName:"Jeff Hirst"},{id:"219866",title:"Dr.",name:"Andrew",middleName:null,surname:"Godwin",slug:"andrew-godwin",fullName:"Andrew Godwin"},{id:"219867",title:"Dr.",name:"Jennifer",middleName:null,surname:"Crow",slug:"jennifer-crow",fullName:"Jennifer Crow"}]},{id:"63228",title:"Ovarian Clear Cell Carcinoma: Metastatic Pathways",slug:"ovarian-clear-cell-carcinoma-metastatic-pathways",totalDownloads:1352,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Ovarian carcinoma reflects the biggest challenge among the field of gynecologic oncology. It represents the most common death cause of genital carcinomas throughout years. The major classification consists of epithelial and non-epithelial types. Due to the histologic origin, epithelial types of ovarian carcinoma are endometrioid, serous-mucinous, and clear cell types. Due to intense metastatic infiltration and rapid tumor spread, clear cell ovarian carcinoma constitutes type of lesion with the most poor prognosis, decreased overall survival, decreased free survival, and poor quality of life of the patient. The metastatic infiltration is strongly accompanied with all significant prognostic factors. All biochemical pathways at the time of the infiltration are correlated with tumor size, lymphatic spread, staging of the lesion, histologic type, and grade of differentiation of the lesion.",book:{id:"7271",slug:"cancer-metastasis",title:"Cancer Metastasis",fullTitle:"Cancer Metastasis"},signatures:"Chrisostomos Sofoudis",authors:[{id:"173802",title:"Dr.",name:"Chrisostomos",middleName:null,surname:"Sofoudis",slug:"chrisostomos-sofoudis",fullName:"Chrisostomos Sofoudis"}]},{id:"27761",title:"Excess Fibroblast Growth Factor-7 (FGF-7) Activates b-Catenin and Leads to Ocular Surface Squamous Neoplasia in Mice",slug:"excess-fibroblast-growth-factor-7-fgf-7-activates-b-catenin-and-leads-to-ocular-surface-squamous-neo",totalDownloads:2528,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"712",slug:"intraepithelial-neoplasia",title:"Intraepithelial Neoplasia",fullTitle:"Intraepithelial Neoplasia"},signatures:"Chia-Yang Liu and Winston W.-Y. Kao",authors:[{id:"88194",title:"Dr.",name:"Chia-Yang",middleName:null,surname:"Liu",slug:"chia-yang-liu",fullName:"Chia-Yang Liu"},{id:"127513",title:"Prof.",name:"Winston W.-Y.",middleName:null,surname:"Kao",slug:"winston-w.-y.-kao",fullName:"Winston W.-Y. Kao"}]},{id:"58059",title:"Novel Systemic Treatments in High Grade Ovarian Cancer",slug:"novel-systemic-treatments-in-high-grade-ovarian-cancer",totalDownloads:1055,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Most patients with ovarian cancer present at an advanced stage and are never cured. To improve outcomes a variety of novel systemic strategies are being developed. Traditional cytotoxic chemotherapy is being optimised, anti-angiogenic strategies are already in the clinic and several PARP inhibitors have gained regulatory approval. In addition, immunotherapy is showing promise and novel targeted strategies including against folate receptor alpha are also generating excitement. As our therapeutic choice increases, a challenge will be how to best utilize the options available. Here we discuss recently established and other emerging therapies with a focus on key concepts rather than detailed synopses of trial designs and outcomes.",book:{id:"5997",slug:"ovarian-cancer-from-pathogenesis-to-treatment",title:"Ovarian Cancer",fullTitle:"Ovarian Cancer - From Pathogenesis to Treatment"},signatures:"Amit Samani, Charleen Chan and Jonathan Krell",authors:[{id:"207859",title:"Dr.",name:"Amit",middleName:null,surname:"Samani",slug:"amit-samani",fullName:"Amit Samani"}]}],onlineFirstChaptersFilter:{topicId:"1080",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:0,limit:8,total:null},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:287,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:10,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"May 18th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:27,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:49,paginationItems:[{id:"80495",title:"Iron in Cell Metabolism and Disease",doi:"10.5772/intechopen.101908",signatures:"Eeka Prabhakar",slug:"iron-in-cell-metabolism-and-disease",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:null,authors:null,book:{title:"Iron Metabolism - Iron a Double‐Edged Sword",coverURL:"https://cdn.intechopen.com/books/images_new/10842.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81799",title:"Cross Talk of Purinergic and Immune Signaling: Implication in Inflammatory and Pathogenic Diseases",doi:"10.5772/intechopen.104978",signatures:"Richa Rai",slug:"cross-talk-of-purinergic-and-immune-signaling-implication-in-inflammatory-and-pathogenic-diseases",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81764",title:"Involvement of the Purinergic System in Cell Death in Models of Retinopathies",doi:"10.5772/intechopen.103935",signatures:"Douglas Penaforte Cruz, Marinna Garcia Repossi and Lucianne Fragel Madeira",slug:"involvement-of-the-purinergic-system-in-cell-death-in-models-of-retinopathies",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81756",title:"Alteration of Cytokines Level and Oxidative Stress Parameters in COVID-19",doi:"10.5772/intechopen.104950",signatures:"Marija Petrusevska, Emilija Atanasovska, Dragica Zendelovska, Aleksandar Eftimov and Katerina Spasovska",slug:"alteration-of-cytokines-level-and-oxidative-stress-parameters-in-covid-19",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}}]},overviewPagePublishedBooks:{paginationCount:27,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. Waisundara",profilePictureURL:"https://mts.intechopen.com/storage/users/194281/images/system/194281.jpg",biography:"Dr. Viduranga Waisundara obtained her Ph.D. in Food Science and Technology from the Department of Chemistry, National University of Singapore, in 2010. She was a lecturer at Temasek Polytechnic, Singapore from July 2009 to March 2013. She relocated to her motherland of Sri Lanka and spearheaded the Functional Food Product Development Project at the National Institute of Fundamental Studies from April 2013 to October 2016. She was a senior lecturer on a temporary basis at the Department of Food Technology, Faculty of Technology, Rajarata University of Sri Lanka. She is currently Deputy Principal of the Australian College of Business and Technology – Kandy Campus, Sri Lanka. She is also the Global Harmonization Initiative (GHI) Ambassador to Sri Lanka.",institutionString:"Australian College of Business & Technology",institution:null}]},{type:"book",id:"6820",title:"Keratin",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6820.jpg",slug:"keratin",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Miroslav Blumenberg",hash:"6def75cd4b6b5324a02b6dc0359896d0",volumeInSeries:2,fullTitle:"Keratin",editors:[{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}}]},{type:"book",id:"7978",title:"Vitamin A",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7978.jpg",slug:"vitamin-a",publishedDate:"May 15th 2019",editedByType:"Edited by",bookSignature:"Leila Queiroz Zepka, Veridiana Vera de Rosso and Eduardo Jacob-Lopes",hash:"dad04a658ab9e3d851d23705980a688b",volumeInSeries:3,fullTitle:"Vitamin A",editors:[{id:"261969",title:"Dr.",name:"Leila",middleName:null,surname:"Queiroz Zepka",slug:"leila-queiroz-zepka",fullName:"Leila Queiroz Zepka",profilePictureURL:"https://mts.intechopen.com/storage/users/261969/images/system/261969.png",biography:"Prof. Dr. Leila Queiroz Zepka is currently an associate professor in the Department of Food Technology and Science, Federal University of Santa Maria, Brazil. She has more than fifteen years of teaching and research experience. She has published more than 550 scientific publications/communications, including 15 books, 50 book chapters, 100 original research papers, 380 research communications in national and international conferences, and 12 patents. She is a member of the editorial board of five journals and acts as a reviewer for several national and international journals. Her research interests include microalgal biotechnology with an emphasis on microalgae-based products.",institutionString:"Universidade Federal de Santa Maria",institution:{name:"Universidade Federal de Santa Maria",institutionURL:null,country:{name:"Brazil"}}}]},{type:"book",id:"7953",title:"Bioluminescence",subtitle:"Analytical Applications and Basic Biology",coverURL:"https://cdn.intechopen.com/books/images_new/7953.jpg",slug:"bioluminescence-analytical-applications-and-basic-biology",publishedDate:"September 25th 2019",editedByType:"Edited by",bookSignature:"Hirobumi Suzuki",hash:"3a8efa00b71abea11bf01973dc589979",volumeInSeries:4,fullTitle:"Bioluminescence - Analytical Applications and Basic Biology",editors:[{id:"185746",title:"Dr.",name:"Hirobumi",middleName:null,surname:"Suzuki",slug:"hirobumi-suzuki",fullName:"Hirobumi Suzuki",profilePictureURL:"https://mts.intechopen.com/storage/users/185746/images/system/185746.png",biography:"Dr. Hirobumi Suzuki received his Ph.D. in 1997 from Tokyo Metropolitan University, Japan, where he studied firefly phylogeny and the evolution of mating systems. He is especially interested in the genetic differentiation pattern and speciation process that correlate to the flashing pattern and mating behavior of some fireflies in Japan. He then worked for Olympus Corporation, a Japanese manufacturer of optics and imaging products, where he was involved in the development of luminescence technology and produced a bioluminescence microscope that is currently being used for gene expression analysis in chronobiology, neurobiology, and developmental biology. Dr. Suzuki currently serves as a visiting researcher at Kogakuin University, Japan, and also a vice president of the Japan Firefly Society.",institutionString:"Kogakuin University",institution:null}]}]},openForSubmissionBooks:{},onlineFirstChapters:{},subseriesFiltersForOFChapters:[],publishedBooks:{},subseriesFiltersForPublishedBooks:[],publicationYearFilters:[],authors:{}},subseries:{item:{id:"22",type:"subseries",title:"Applied Intelligence",keywords:"Machine Learning, Intelligence Algorithms, Data Science, Artificial Intelligence, Applications on Applied Intelligence",scope:"This field is the key in the current industrial revolution (Industry 4.0), where the new models and developments are based on the knowledge generation on applied intelligence. The motor of the society is the industry and the research of this topic has to be empowered in order to increase and improve the quality of our lives.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/22.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11418,editor:{id:"27170",title:"Prof.",name:"Carlos",middleName:"M.",surname:"Travieso-Gonzalez",slug:"carlos-travieso-gonzalez",fullName:"Carlos Travieso-Gonzalez",profilePictureURL:"https://mts.intechopen.com/storage/users/27170/images/system/27170.jpeg",biography:"Carlos M. Travieso-González received his MSc degree in Telecommunication Engineering at Polytechnic University of Catalonia (UPC), Spain in 1997, and his Ph.D. degree in 2002 at the University of Las Palmas de Gran Canaria (ULPGC-Spain). He is a full professor of signal processing and pattern recognition and is head of the Signals and Communications Department at ULPGC, teaching from 2001 on subjects on signal processing and learning theory. His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. He is the founder of The IEEE IWOBI conference series and the president of its Steering Committee, as well as the founder of both the InnoEducaTIC and APPIS conference series. He is an evaluator of project proposals for the European Union (H2020), Medical Research Council (MRC, UK), Spanish Government (ANECA, Spain), Research National Agency (ANR, France), DAAD (Germany), Argentinian Government, and the Colombian Institutions. He has been a reviewer in different indexed international journals (<70) and conferences (<250) since 2001. He has been a member of the IASTED Technical Committee on Image Processing from 2007 and a member of the IASTED Technical Committee on Artificial Intelligence and Expert Systems from 2011. \n\nHe has held the general chair position for the following: ACM-APPIS (2020, 2021), IEEE-IWOBI (2019, 2020 and 2020), A PPIS (2018, 2019), IEEE-IWOBI (2014, 2015, 2017, 2018), InnoEducaTIC (2014, 2017), IEEE-INES (2013), NoLISP (2011), JRBP (2012), and IEEE-ICCST (2005)\n\nHe is an associate editor of the Computational Intelligence and Neuroscience Journal (Hindawi – Q2 JCR-ISI). He was vice dean from 2004 to 2010 in the Higher Technical School of Telecommunication Engineers at ULPGC and the vice dean of Graduate and Postgraduate Studies from March 2013 to November 2017. He won the “Catedra Telefonica” Awards in Modality of Knowledge Transfer, 2017, 2018, and 2019 editions, and awards in Modality of COVID Research in 2020.\n\nPublic References:\nResearcher ID http://www.researcherid.com/rid/N-5967-2014\nORCID https://orcid.org/0000-0002-4621-2768 \nScopus Author ID https://www.scopus.com/authid/detail.uri?authorId=6602376272\nScholar Google https://scholar.google.es/citations?user=G1ks9nIAAAAJ&hl=en \nResearchGate https://www.researchgate.net/profile/Carlos_Travieso",institutionString:null,institution:{name:"University of Las Palmas de Gran Canaria",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,series:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403"},editorialBoard:[{id:"13633",title:"Prof.",name:"Abdelhamid",middleName:null,surname:"Mellouk",slug:"abdelhamid-mellouk",fullName:"Abdelhamid Mellouk",profilePictureURL:"https://mts.intechopen.com/storage/users/13633/images/1567_n.jpg",institutionString:null,institution:{name:"Paris 12 Val de Marne University",institutionURL:null,country:{name:"France"}}},{id:"109268",title:"Dr.",name:"Ali",middleName:null,surname:"Al-Ataby",slug:"ali-al-ataby",fullName:"Ali Al-Ataby",profilePictureURL:"https://mts.intechopen.com/storage/users/109268/images/7410_n.jpg",institutionString:null,institution:{name:"University of Liverpool",institutionURL:null,country:{name:"United Kingdom"}}},{id:"3807",title:"Dr.",name:"Carmelo",middleName:"Jose Albanez",surname:"Bastos-Filho",slug:"carmelo-bastos-filho",fullName:"Carmelo Bastos-Filho",profilePictureURL:"https://mts.intechopen.com/storage/users/3807/images/624_n.jpg",institutionString:null,institution:{name:"Universidade de Pernambuco",institutionURL:null,country:{name:"Brazil"}}},{id:"38850",title:"Dr.",name:"Efren",middleName:null,surname:"Gorrostieta Hurtado",slug:"efren-gorrostieta-hurtado",fullName:"Efren Gorrostieta Hurtado",profilePictureURL:"https://mts.intechopen.com/storage/users/38850/images/system/38850.jpg",institutionString:null,institution:{name:"Autonomous University of Queretaro",institutionURL:null,country:{name:"Mexico"}}},{id:"239041",title:"Prof.",name:"Yang",middleName:null,surname:"Yi",slug:"yang-yi",fullName:"Yang Yi",profilePictureURL:"https://mts.intechopen.com/storage/users/239041/images/system/239041.jpeg",institutionString:"Virginia Tech",institution:{name:"Virginia Tech",institutionURL:null,country:{name:"United States of America"}}}]},onlineFirstChapters:{paginationCount:17,paginationItems:[{id:"81647",title:"Diabetes and Epigenetics",doi:"10.5772/intechopen.104653",signatures:"Rasha A. Alhazzaa, Thomas Heinbockel and Antonei B. Csoka",slug:"diabetes-and-epigenetics",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Epigenetics to Optogenetics - A New Paradigm in the Study of Biology",coverURL:"https://cdn.intechopen.com/books/images_new/9672.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"81099",title:"SK Channels and Heart Disease",doi:"10.5772/intechopen.104115",signatures:"Katherine Zhong, Shawn Kant, Frank Sellke and Jun Feng",slug:"sk-channels-and-heart-disease",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Ion Channels - From Basic Properties to Medical Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10838.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"80967",title:"Hot on the Trail of Skin Inflammation: Focus on TRPV1/TRPV3 Channels in Psoriasis",doi:"10.5772/intechopen.103792",signatures:"Lisa S. Martin, Emma Fraillon, Fabien P. Chevalier and Bérengère Fromy",slug:"hot-on-the-trail-of-skin-inflammation-focus-on-trpv1-trpv3-channels-in-psoriasis",totalDownloads:24,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Ion Channels - From Basic Properties to Medical Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10838.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"80952",title:"TRPV Family Ion Channels in the Mammary Epithelium: Role in Normal Tissue Homeostasis and along Breast Cancer Progression",doi:"10.5772/intechopen.103665",signatures:"Sari Susanna Tojkander",slug:"trpv-family-ion-channels-in-the-mammary-epithelium-role-in-normal-tissue-homeostasis-and-along-breas",totalDownloads:17,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Ion Channels - From Basic Properties to Medical Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10838.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"80484",title:"The Use of Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) to Study Ivermectin-Mediated Molecular Pathway Changes in Human Ovarian Cancer Cells",doi:"10.5772/intechopen.102092",signatures:"Na Li and Xianquan Zhan",slug:"the-use-of-stable-isotope-labeling-with-amino-acids-in-cell-culture-silac-to-study-ivermectin-mediat",totalDownloads:78,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Cell Culture - Advanced Technology and Applications in Medical and Life Sciences",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"80157",title:"Structural Determinants for Ligand Accommodation in Voltage Sensors",doi:"10.5772/intechopen.102094",signatures:"Abigail García-Morales, Aylin López-Palestino and Daniel Balleza",slug:"structural-determinants-for-ligand-accommodation-in-voltage-sensors",totalDownloads:86,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Ion Channels - From Basic Properties to Medical Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10838.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"79690",title:"Mitochondrial Channels and their Role in Cardioprotection",doi:"10.5772/intechopen.101127",signatures:"Keerti Mishra and Min Luo",slug:"mitochondrial-channels-and-their-role-in-cardioprotection",totalDownloads:84,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Ion Channels - From Basic Properties to Medical Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10838.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"79031",title:"Isolation and Expansion of Mesenchymal Stem/Stromal Cells, Functional Assays and Long-Term Culture Associated Alterations of Cellular Properties",doi:"10.5772/intechopen.100286",signatures:"Chenghai Li",slug:"isolation-and-expansion-of-mesenchymal-stem-stromal-cells-functional-assays-and-long-term-culture-as",totalDownloads:74,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Cell Culture - Advanced Technology and Applications in Medical and Life Sciences",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"78960",title:"Two-Dimensional and Three-Dimensional Cell Culture and Their Applications",doi:"10.5772/intechopen.100382",signatures:"Sangeeta Ballav, Ankita Jaywant Deshmukh, Shafina Siddiqui, Jyotirmoi Aich and Soumya Basu",slug:"two-dimensional-and-three-dimensional-cell-culture-and-their-applications",totalDownloads:249,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Cell Culture - Advanced Technology and Applications in Medical and Life Sciences",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"78812",title:"Nanotechnology Application and Intellectual Property Right Prospects of Mammalian Cell Culture",doi:"10.5772/intechopen.99146",signatures:"Harikrishnareddy Rachamalla, Anubhab Mukherjee and Manash K. Paul",slug:"nanotechnology-application-and-intellectual-property-right-prospects-of-mammalian-cell-culture",totalDownloads:119,totalCrossrefCites:1,totalDimensionsCites:1,authors:null,book:{title:"Cell Culture - Advanced Technology and Applications in Medical and Life Sciences",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"78274",title:"A Brief Concept of Cell Culture: Challenges, Prospects and Applications",doi:"10.5772/intechopen.99387",signatures:"Md. Salauddin",slug:"a-brief-concept-of-cell-culture-challenges-prospects-and-applications",totalDownloads:171,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Cell Culture - Advanced Technology and Applications in Medical and Life Sciences",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"78415",title:"Epigenetic",doi:"10.5772/intechopen.99964",signatures:"Mehmet Ünal",slug:"epigenetic",totalDownloads:135,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Epigenetics to Optogenetics - A New Paradigm in the Study of Biology",coverURL:"https://cdn.intechopen.com/books/images_new/9672.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"77443",title:"Cyanobacterial Phytochromes in Optogenetics",doi:"10.5772/intechopen.97522",signatures:"Sivasankari Sivaprakasam, Vinoth Mani, Nagalakshmi Balasubramaniyan and David Ravindran Abraham",slug:"cyanobacterial-phytochromes-in-optogenetics",totalDownloads:184,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Epigenetics to Optogenetics - A New Paradigm in the Study of Biology",coverURL:"https://cdn.intechopen.com/books/images_new/9672.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"75979",title:"Spatiotemporal Regulation of Cell–Cell Adhesions",doi:"10.5772/intechopen.97009",signatures:"Brent M. Bijonowski",slug:"spatiotemporal-regulation-of-cell-cell-adhesions",totalDownloads:170,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Epigenetics to Optogenetics - A New Paradigm in the Study of Biology",coverURL:"https://cdn.intechopen.com/books/images_new/9672.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"76646",title:"Functional Mechanism of Proton Pump-Type Rhodopsins Found in Various Microorganisms as a Potential Effective Tool in Optogenetics",doi:"10.5772/intechopen.97589",signatures:"Jun Tamogami and Takashi Kikukawa",slug:"functional-mechanism-of-proton-pump-type-rhodopsins-found-in-various-microorganisms-as-a-potential-e",totalDownloads:197,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Epigenetics to Optogenetics - A New Paradigm in the Study of Biology",coverURL:"https://cdn.intechopen.com/books/images_new/9672.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"76510",title:"Evolution of Epigenome as the Blueprint for Carcinogenesis",doi:"10.5772/intechopen.97379",signatures:"Zeenat Farooq, Ambreen Shah, Mohammad Tauseef, Riyaz A. Rather and Mumtaz Anwar",slug:"evolution-of-epigenome-as-the-blueprint-for-carcinogenesis",totalDownloads:190,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Epigenetics to Optogenetics - A New Paradigm in the Study of Biology",coverURL:"https://cdn.intechopen.com/books/images_new/9672.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}}]},publishedBooks:{paginationCount:4,paginationItems:[{type:"book",id:"9869",title:"Self-Driving Vehicles and Enabling Technologies",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9869.jpg",slug:"self-driving-vehicles-and-enabling-technologies",publishedDate:"September 22nd 2021",editedByType:"Edited by",bookSignature:"Marian Găiceanu",hash:"fd451ca2e4785ef098e04b7d695a18d9",volumeInSeries:6,fullTitle:"Self-Driving Vehicles and Enabling Technologies",editors:[{id:"169608",title:"Prof.",name:"Marian",middleName:null,surname:"Găiceanu",slug:"marian-gaiceanu",fullName:"Marian Găiceanu",profilePictureURL:"https://mts.intechopen.com/storage/users/169608/images/system/169608.png",institutionString:'"Dunarea de Jos" University of Galati',institution:{name:'"Dunarea de Jos" University of Galati',institutionURL:null,country:{name:"Romania"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9958",title:"Artificial Intelligence",subtitle:"Latest Advances, New Paradigms and Novel Applications",coverURL:"https://cdn.intechopen.com/books/images_new/9958.jpg",slug:"artificial-intelligence-latest-advances-new-paradigms-and-novel-applications",publishedDate:"September 1st 2021",editedByType:"Edited by",bookSignature:"Eneko Osaba, Esther Villar, Jesús L. Lobo and Ibai Laña",hash:"39648fbfdaa11385097d62b1f13aad54",volumeInSeries:5,fullTitle:"Artificial Intelligence - Latest Advances, New Paradigms and Novel Applications",editors:[{id:"221364",title:"Dr.",name:"Eneko",middleName:null,surname:"Osaba",slug:"eneko-osaba",fullName:"Eneko Osaba",profilePictureURL:"https://mts.intechopen.com/storage/users/221364/images/system/221364.jpg",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",institutionURL:null,country:{name:"Spain"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7656",title:"Fuzzy Logic",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7656.jpg",slug:"fuzzy-logic",publishedDate:"February 5th 2020",editedByType:"Edited by",bookSignature:"Constantin Volosencu",hash:"54f092d4ffe0abf5e4172a80025019bc",volumeInSeries:3,fullTitle:"Fuzzy Logic",editors:[{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu",profilePictureURL:"https://mts.intechopen.com/storage/users/1063/images/system/1063.png",institutionString:"Polytechnic University of Timişoara",institution:{name:"Polytechnic University of Timişoara",institutionURL:null,country:{name:"Romania"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7723",title:"Artificial Intelligence",subtitle:"Applications in Medicine and Biology",coverURL:"https://cdn.intechopen.com/books/images_new/7723.jpg",slug:"artificial-intelligence-applications-in-medicine-and-biology",publishedDate:"July 31st 2019",editedByType:"Edited by",bookSignature:"Marco Antonio Aceves-Fernandez",hash:"a3852659e727f95c98c740ed98146011",volumeInSeries:1,fullTitle:"Artificial Intelligence - Applications in Medicine and Biology",editors:[{id:"24555",title:"Dr.",name:"Marco Antonio",middleName:null,surname:"Aceves Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves Fernandez",profilePictureURL:"https://mts.intechopen.com/storage/users/24555/images/system/24555.jpg",institutionString:"Universidad Autonoma de Queretaro",institution:{name:"Autonomous University of Queretaro",institutionURL:null,country:{name:"Mexico"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.jpg",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}}]},submityourwork:{pteSeriesList:[],lsSeriesList:[],hsSeriesList:[],sshSeriesList:[],subseriesList:[],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:null},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/78394",hash:"",query:{},params:{id:"78394"},fullPath:"/chapters/78394",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()