IntechOpen was founded by scientists, for scientists, in order to make book publishing accessible around the globe. Over the last two decades, this has driven Open Access (OA) book publishing whilst levelling the playing field for global academics. Through our innovative publishing model and the support of the research community, we have now published over 5,700 Open Access books and are visited online by over three million academics every month. These researchers are increasingly working in broad technology-based subjects, driving multidisciplinary academic endeavours into human health, environment, and technology.
\\n\\n
By listening to our community, and in order to serve these rapidly growing areas which lie at the core of IntechOpen's expertise, we are launching a portfolio of Open Science journals:
All three journals will publish under an Open Access model and embrace Open Science policies to help support the changing needs of academics in these fast-moving research areas. There will be direct links to preprint servers and data repositories, allowing full reproducibility and rapid dissemination of published papers to help accelerate the pace of research. Each journal has renowned Editors in Chief who will work alongside a global Editorial Board, delivering robust single-blind peer review. Supported by our internal editorial teams, this will ensure our authors will receive a quick, user-friendly, and personalised publishing experience.
\\n\\n
"By launching our journals portfolio we are introducing new, dedicated homes for interdisciplinary technology-focused researchers to publish their work, whilst embracing Open Science and creating a unique global home for academics to disseminate their work. We are taking a leap toward Open Science continuing and expanding our fundamental commitment to openly sharing scientific research across the world, making it available for the benefit of all." Dr. Sara Uhac, IntechOpen CEO
\\n\\n
"Our aim is to promote and create better science for a better world by increasing access to information and the latest scientific developments to all scientists, innovators, entrepreneurs and students and give them the opportunity to learn, observe and contribute to knowledge creation. Open Science promotes a swifter path from research to innovation to produce new products and services." Alex Lazinica, IntechOpen founder
\\n\\n
In conclusion, Natalia Reinic Babic, Head of Journal Publishing and Open Science at IntechOpen adds:
\\n\\n
“On behalf of the journal team I’d like to thank all our Editors in Chief, Editorial Boards, internal supporting teams, and our scientific community for their continuous support in making this portfolio a reality - we couldn’t have done it without you! With your support in place, we are confident these journals will become as impactful and successful as our book publishing program and bring us closer to a more open (science) future.”
\\n\\n
We invite you to visit the journals homepage and learn more about the journal’s Editorial Boards, scope and vision as all three journals are now open for submissions.
\\n\\n
Feel free to share this news on social media and help us mark this memorable moment!
After years of being acknowledged as the world's leading publisher of Open Access books, today, we are proud to announce we’ve successfully launched a portfolio of Open Science journals covering rapidly expanding areas of interdisciplinary research.
\n\n\n\n
IntechOpen was founded by scientists, for scientists, in order to make book publishing accessible around the globe. Over the last two decades, this has driven Open Access (OA) book publishing whilst levelling the playing field for global academics. Through our innovative publishing model and the support of the research community, we have now published over 5,700 Open Access books and are visited online by over three million academics every month. These researchers are increasingly working in broad technology-based subjects, driving multidisciplinary academic endeavours into human health, environment, and technology.
\n\n
By listening to our community, and in order to serve these rapidly growing areas which lie at the core of IntechOpen's expertise, we are launching a portfolio of Open Science journals:
All three journals will publish under an Open Access model and embrace Open Science policies to help support the changing needs of academics in these fast-moving research areas. There will be direct links to preprint servers and data repositories, allowing full reproducibility and rapid dissemination of published papers to help accelerate the pace of research. Each journal has renowned Editors in Chief who will work alongside a global Editorial Board, delivering robust single-blind peer review. Supported by our internal editorial teams, this will ensure our authors will receive a quick, user-friendly, and personalised publishing experience.
\n\n
"By launching our journals portfolio we are introducing new, dedicated homes for interdisciplinary technology-focused researchers to publish their work, whilst embracing Open Science and creating a unique global home for academics to disseminate their work. We are taking a leap toward Open Science continuing and expanding our fundamental commitment to openly sharing scientific research across the world, making it available for the benefit of all." Dr. Sara Uhac, IntechOpen CEO
\n\n
"Our aim is to promote and create better science for a better world by increasing access to information and the latest scientific developments to all scientists, innovators, entrepreneurs and students and give them the opportunity to learn, observe and contribute to knowledge creation. Open Science promotes a swifter path from research to innovation to produce new products and services." Alex Lazinica, IntechOpen founder
\n\n
In conclusion, Natalia Reinic Babic, Head of Journal Publishing and Open Science at IntechOpen adds:
\n\n
“On behalf of the journal team I’d like to thank all our Editors in Chief, Editorial Boards, internal supporting teams, and our scientific community for their continuous support in making this portfolio a reality - we couldn’t have done it without you! With your support in place, we are confident these journals will become as impactful and successful as our book publishing program and bring us closer to a more open (science) future.”
\n\n
We invite you to visit the journals homepage and learn more about the journal’s Editorial Boards, scope and vision as all three journals are now open for submissions.
\n\n
Feel free to share this news on social media and help us mark this memorable moment!
\n\n
\n'}],latestNews:[{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"},{slug:"intechopen-identified-as-one-of-the-most-significant-contributor-to-oa-book-growth-in-doab-20210809",title:"IntechOpen Identified as One of the Most Significant Contributors to OA Book Growth in DOAB"}]},book:{item:{type:"book",id:"1045",leadTitle:null,fullTitle:"Nanocomposites and Polymers with Analytical Methods",title:"Nanocomposites and Polymers with Analytical Methods",subtitle:null,reviewType:"peer-reviewed",abstract:"This book contains 16 chapters. In the first part, there are 8 chapters describing new materials and analytic methods. These materials include chapters on gold nanoparticles and Sol-Gel metal oxides, nanocomposites with carbon nanotubes, methods of evaluation by depth sensing, and other methods. The second part contains 3 chapters featuring new materials with unique properties including optical non-linearities, new materials based on pulp fibers, and the properties of nano-filled polymers. The last part contains 5 chapters with applications of new materials for medical devices, anodes for lithium batteries, electroceramics, phase change materials and matrix active nanoparticles.",isbn:null,printIsbn:"978-953-307-352-1",pdfIsbn:"978-953-51-4463-2",doi:"10.5772/1548",price:139,priceEur:155,priceUsd:179,slug:"nanocomposites-and-polymers-with-analytical-methods",numberOfPages:418,isOpenForSubmission:!1,isInWos:1,isInBkci:!0,hash:"65d477e855685ea85913e5aba0c5217e",bookSignature:"John Cuppoletti",publishedDate:"August 9th 2011",coverURL:"https://cdn.intechopen.com/books/images_new/1045.jpg",numberOfDownloads:110507,numberOfWosCitations:234,numberOfCrossrefCitations:73,numberOfCrossrefCitationsByBook:11,numberOfDimensionsCitations:216,numberOfDimensionsCitationsByBook:19,hasAltmetrics:1,numberOfTotalCitations:523,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"October 18th 2010",dateEndSecondStepPublish:"November 15th 2010",dateEndThirdStepPublish:"March 22nd 2011",dateEndFourthStepPublish:"April 21st 2011",dateEndFifthStepPublish:"June 20th 2011",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,7,8",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"49991",title:"Dr.",name:"John",middleName:null,surname:"Cuppoletti",slug:"john-cuppoletti",fullName:"John Cuppoletti",profilePictureURL:"https://mts.intechopen.com/storage/users/49991/images/1860_n.jpg",biography:"Dr. Cuppoletti is Professor of Molecular and Cellular Physiology at the University of Cincinnati. (Ph.D. 1977 University of California, Davis). His research interests include pumps, carriers, and ion channels of the epithelia. In recent years, potassium and chloride channel regulation, pharmacology, and molecular engineering have become increasingly important tools with which to study the functional mechanisms of these proteins. More recently, as the X-ray crystal structures of these proteins have become available, it has become possible to combine these types of studies with computational chemistry approaches in attempts to understand how the structure relates to the function of these proteins. These transport proteins have been placed into synthetic membranes in order to obtain more detailed information regarding protein function that cannot be obtained from purely biological membranes. The natural and engineered proteins in these membranes are functional, and have led to the development of many interesting devices. Examples include drug screening devices, devices for identification of toxic bacterial products, and membranes for use in fuel cells.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"3",institution:{name:"University of Cincinnati",institutionURL:null,country:{name:"United States of America"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1169",title:"Condensed Matter Physics",slug:"nanotechnology-and-nanomaterials-material-science-condensed-matter-physics"}],chapters:[{id:"17184",title:"Polymer Nanocomposites: From Synthesis to Applications",doi:"10.5772/17039",slug:"polymer-nanocomposites-from-synthesis-to-applications",totalDownloads:17291,totalCrossrefCites:31,totalDimensionsCites:68,hasAltmetrics:0,abstract:null,signatures:"S. Anandhan and S. 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1. Introduction
Fading air quality in India has moved towards malnutrition, for the past few decades. India remain one of the countries where 1.9 million untimely deaths take place due to worsening ambient air quality. The estimated financial losses caused due to air pollution in India are placed at 885 billion rupees [1, 2]. Revelation to outside air pollutants will enlarge the menace of Arrhythmia, Ischemia, Cardiac Failure and Stroke. Air quality data in Solapur has been analyzed to scrutinize its condition and to recognize its health situation.
The goal of this chapter is to tale on the development of a cost effective air quality monitoring system using wireless sensor network (WSN) and IoT, deployed in polluted areas of Solapur. The air quality in Solapur had been a tight rope walk for its citizens over the past decades [3]. Growth of Solapur had lead to rise in number of vehicles on the roads, creating supplementary pollution predicament with smoke emanation and other pollutants. Apart from the increase in vehicles, other reasons for escalating vehicular contamination are the varieties of engines used, crowded traffic, pitiable road conditions and dry climatic conditions. Solapur Municipal Corporation in alliance with Central Pollution Control Board and State Pollution Control Board has installed air quality monitoring system as an attempt of Swacch Bharat Abhiyan Project.
As data logger and hardware mechanism are not used, the present system is more superficial and user friendly. It was resolved to bail out air pollution monitoring in high traffic zones of Solapur city where pollutants exceeded the ambient air quality values as proposed by Central Pollution Control Board (CPCB). The system uses Wireless Sensor Network and IoT technology for air quality monitoring. Hitherto, the predictable monitoring system is massive, luxurious and power consuming. Therefore, incompatibility associated using wired monitoring system is replaced with a new wireless air monitoring system which is cost-effective and competent with stumpy power spending [4]. Wireless sensor networks (WSNs) are paying attention in the industry also in academia because of their significant relevance and associated security challenges. The utility of this network is to collect the data from the environment and fling it to the sink node. The present system consists of the five sensor nodes and one sink node. The chic sensor nodes are least-power gadgets outfitted with one or more sensors, microcontroller, a power supply and radio. An array of different sensors can be allied to the mote to determine environment parameters. With the establishment of ‘Solapur’ as smart city it becomes pertinent to employ the WSN for monitoring AAQ protocols. The smart city projects in Solapur is obligatory to put up a superior air quality monitoring system in terms of rate, power competence, ability by using contemptible handy ambient sensors. The use of IoT (Internet of Things) provides the remote monitoring of our system [5]. Internet of Things has a backbone of diverse technologies- Wireless Sensor Networks, Embedded Systems, Security Protocols and Architectures, network services, Internet and Search Engines and Cloud Computing. The internet of things (IoT) is a system of unified computing gadgets, automatic and digital tackle, items, group that are provided with unique identifiers and the capability to convey data in excess of a network with no requiring user-to-user or user-to-computer dealings. Devices that work on IoT, distribute the sensor information; they amass by linking to an IoT gateway where data is sent to the cloud to be analyzed. The block diagram, Figure 1 represents the proposed system. The use of open source IoT web server platform, to ensure an enduring storage as well as real time monitoring of air quality monitoring data makes the system more superior than the traditional data logger system. Use of flawless incorporation of smart mobile standards, WSN, and several other sensing technologies makes this system more scalable and smart. Uses of XBee wireless protocol make the system least power consumable.
Figure 1.
Block diagram of a proposed system.
2. Wireless sensor network setup for air quality monitoring system
A wireless sensor network is compacted in behavior. Generally, it provides thousands of irrelevant devices, called as sensor nodes and are incorporated to gather the data from assorted assets. The sink node collects the data from sensor node and provides necessary action on it.
2.1 Sensor node (mote)
The motes are constructed with four components (Figure 1), 1. Processing part made up of controller (Arduino UNO) 2. Wireless element for presuming wireless communication amid nodes (XBee) 3. Sensor to convert environment data into electrical quantity and 4. Batteries to offer power supply to the network [6]. Every constituent plays an important task in the operation of motes. Radio subsystem uses various techniques such as Bluetooth, XBee and UWB that operates at ISM band frequency of 2.4 GHz for wireless transmission. Microprocessor or microcontroller subsystem is used to offer logical decision regarding controlling of air quality monitoring system. To save energy, controller works in off, sleep, idle and active modes depending on the condition of the sensor nodes.
An array of sensors at the motes is as follows:
2.1.1 CO sensor (MQ-7)
MQ-7 Carbon monoxide sensor can sense CO gas and sends both digital and analog signals to Arduino. According to its datasheet, the MQ-7 sensor detects 20 to 2000 ppm of CO in air [7]. Its standard circuit represented in Figure 2. The interfacing of sensor to the arduino uno is shown in Figure 3.
Figure 2.
Standard circuit.
Figure 3.
Arduino interfacing of sensor.
The sensor has to be calibrated at 200 ppm of CO with RL at 10KΩ. The load resistance RL vary from 5KΩ to 47 KΩ. Its operating temperature range is from 20oc to 50oc. The surface resistance Rs varies from 2KΩ to 20KΩ. Rs can be calculated by the following formula.
RsRl=Vc−VRl/VRl
From the datasheets, calibration of sensor in terms of ppm is done as follows.
Concentration ofgasppm=3.027∗e^32.85∗V−RL)
2.1.2 Temperature sensor (LM-35)
LM-35 is an analog temperature sensor. It is connected to A1 of arduino UNO microcontroller at sensor node. It is shown in Figure 4.
Figure 4.
Lm-35.
Vitally, LM-35 is pre-calibrated in degree celsius to be used for temperature sensor IC. It is linear in characteristics. It does not require any external calibration and gives +10-mV/°C scale facet [8]. Accordingly, the arduino encoding is carried out and its outcomes are displayed on arduino serial monitor window. The characteristic curve and arduino interfacing of LM-35 is displayed in Figures 5 and 6, respectively.
Figure 5.
LM-35 characteristics curve.
Figure 6.
Arduino interfacing.
2.1.3 MQ-135(NOx and SPM sensor)
The calibrated MQ-135 air quality sensor is used for detecting an extensive series of parameters, including NH3, NOx, alcohol, benzene, SPM and CO2. But, it shows high sensitivity for NOx and SPM [9]. Its characteristics curve is shown in Figures 7 and 8.
Figure 7.
Characteristics curve of MQ-135.
Figure 8.
MQ-135.
2.1.4 Atmega 328 (controlling unit)
The Atmega 328 is an entrenched board having inbuilt USB proficiency. The minuscule and user approachable temperament makes it finer than other sophisticated microcontrollers. These microcontrollers encompass additional inbuilt amenities like +5 V, analog and digital pins. It does not comprise on board power jack. Owing to the auto switching potential of the microcontroller, no exterior power jumper is necessary [10]. It posses assorted on board pins and have advanced features as follows:
An automatic reset
On chip broadcast and reception LED’s
Automatic switching to input power.
Inbuilt USB flair for serial communication
Consequently, the WSN nodes are premeditated using arduino nano-microcontroller. An actual pin specification of arduino nano is depicted in Figure 9.
Figure 9.
Arduino nano pin configurations.
2.1.5 XBee protocol
XBee is perched to suit the comprehensive control/sensor network standard. Usually, this module consists of a 16-bit microcontroller amid all parts as some 16 – bit microcontroller might have (ADC, timer, watchdog, sleep timer, UART, general-purpose I/O port….etc.). The schematic representation of XBee is shown in Figure 10.
Figure 10.
XBee.
Owing to the compensation of XBee technology like squat rate and stumpy power working modes and its topologies, this diminutive range communication technology is most excellent, suitable for numerous applications compared to other communications technologies such as Bluetooth, WI-FI, [11] etc. The PCB layout of sensor node drawn is shown in Figure 11.
Figure 11.
PCB layout of the sensor node.
The sink node of air pollution monitoring system is shown in Figure 12.
Figure 12.
Sink node setup of the present system.
3. IoT (internet of things)
The IoT based air contamination monitoring system can be created via sensors and microcontrollers existing in the marketplace. The sink nodes are programmed to collect the data from the mote and transmit it to the cloud. An algorithm is proposed to examine the data and hurl it to the smart phone app. Smartphone app will be developed for user to access the air quality information in real-time [12, 13]. The IoT monitoring is scamper on the communication protocol maneuver. Internet of Things is now verdict reflective exploit in each and every area, plays an important role in this monitoring system too. This system monitors the effluence source from anywhere via PC or mobile. The system shows the air pollution in ppm on webpage, accordingly continuous monitoring can be done. IoT makes almost all “smart” which ameliorate aspects of our existence with the supremacy of data collection and networks. The thing in IoT can compared to be similar to a human being amid a diabetes supervise embed, an animal with tracking plans, etc. The basic block of IoT is depicted in Figure 13.
Figure 13.
Basic blocks of IoT.
3.1 Blynk platform
Blynk is a podium with iOS and Android apps to control Arduino over the internet and is shown in Figure 14. It is a digital control panel where we can construct a advantage for our system by just dragging and dropping gadget. Blynk can manage hardware distantly. Blynk server provides control over communication among the smartphone and hardware. It is an open source platform and be able to lever thousands of devices. Blynk Libraries are accessible and designed for almost all hardware platforms. These libraries help to communicate with the server and operate all inward and extrovert commands [14]. By pressing any key on Blynk app on the smartphone, the signal moves to the Blynk Cloud.
Figure 14.
Blynk platform.
4. LabVIEW
LabVIEW is a software improvement environment produced by National Instruments. In order to recognize a real time data acquisition, LabVIEW is introduced. LabVIEW is worned to execute the system. The system investigates level of the entire connected sensor. At first, it was attentive on intriguing measurements from assorted lab instruments; however it has extended significantly from its initiation. LabVIEW is not a coding language, it is a graphical environment. The coding is actually called “G” code. It is a graphical indoctrination language that uses icons as a substitute of lines of text to build applications; it uses a dataflow encoding to resolve recital [15]. This software is straight forward to handle as it does not require an immense programming skills. The benefit of LabVIEW is prompt and uncomplicated erection of the graphical user interface (GUI) that process the refurbishing of parameters (without interfering with the code) and well-designed appearance of results. Tools used in LabVIEW is illustrated in Figure 15.
Figure 15.
Toolkits in LabVIEW.
5. Working of the system
The system proposes a design to fit monitoring applications on smartphones. Wireless sensors positioned at planned locations sense the level of carbon monoxide, nitrous oxide, humidity and temperature in the air. It provides simple access to the users to supervise real time air quality in their vicinity. It uses cost-effective and readily accessible devices such as an air quality sensor, carbon monoxide gas sensor, nitrous oxide gas sensor and SY-HS220 sensor. Microcontrollers are used at the sensor node for supervising these sensors. The sink node collects the data from sensor node and transfers it to the cloud database through wi-fi module. In the cloud, the data analysis is done so that the society takes measures to mitigate air pollution.
5.1 Accomplishment of a system to attain a data from sensor node(mote)
The air quality monitoring technique involves an interface among Arduino and LabVIEW software. The received values are keep in an Excel sheet and plotted on a chart. The LabVIEW programming for partition of data from each mote would be executed. The co-ordinator node is interfaced with LabVIEW through VISA function tool [16]. The co-ordinator node collects the data from each mote and separated in LabVIEW and is shown in Figures 16 and 17.
Figure 16.
LabVIEW mote data management.
Figure 17.
GUI developed in LabVIEW for mote separation.
6. Comparative analysis of current system with air quality status of Maharashtra 2019–2020 for Solapur City
For comparative study of the current system with traditional system, it has been envisaged one of the regions of Solapur city. Solapur is the fourth major city in the state of Maharashtra which has been racing simultaneously with first, second and third stages of industrial development. Solapur had hit the national headlines for being the most polluted city in India next to surat during 2001.As national ambient air quality standards the solapur municipal corporation has installed electronic sensors to detect SPM-10, SPM-2.5, NOx, SO2, CO apart from temperature, humidity, rainfall etc. Various studies titled “An insight into the unseen: A case study of AAQ in Solapur city [17]”, “Air affair in the proposed smart city of Solapur [18]”. The finding indicates SPM-10 to be causing worry for the citizen and is largely on the higher side of tolerance limit during the dry months. Various mitigation measures such as plantation, golf courses etc. were proposed. The present smart WSN and IoT based system be installed at various stations of WIT campus area, collected data and were displayed on Android App developed on users mobile phone, on Blynk Platform, on LabVIEW Front Panel and Arduino serial monitor window. The prime advantage of developed system is that remote monitoring and controlling of air quality has been initiated. The monthly average reading recorded at WIT Campus, Solapur by CPCB (Central Pollution Control Board) is shown in Table 1. Its graphical representation is shown in Figure 18.
Station name
Year
Month
Average of SO2
Average of NOx
Average of RSPM
WIT campus
2019
Apr
18
36
82
May
18
37
86
Jun
19
38
81
Jul
19
37
79
Aug
17
35
75
Sep
14
33
69
Oct
13
32
68
Nov
13
33
67
Dec
12
32
69
2020
Jan
12
32
68
Feb
12
32
71
Mar
12
32
71
Table 1.
Statistics for monthly average interpretation recorded at WIT campus.
Figure 18.
Monthly standard analysis recorded at WIT campus.
After deploying the sensor nodes at different locations of WIT campus, the data gathered at co-ordinator node is presented in Table 2. The proposed system measures the various air quality parameters such as NOx, RSPM, Temperature, Humidity, CO etc. Their GUI (Graphical User Interface) on LabVIEW is shown in Figures 19–21, respectively.
Station name
Year
Month
Average of NOx
Average of RSPM
Average of temp.
Average of humidity
Average of CO
WIT Campus
2019
Apr
38
100
44
28
120
May
35
95
43
30
118
Jun
38
88
40
33
115
Jul
33
78
38
36
140
Aug
34
72
33
40
100
Sep
38
70
33
40
90
Oct
31
69
32
39
88
Nov
30
63
32
39
83
Dec
31
68
34
32
79
2020
Jan
32
69
33
29
78
Feb
31
69
32
29
75
Mar
31
69
32
30
75
Table 2.
Statistics for monthly average recorded at WIT campus by co-ordinator node.
Figure 19.
Graphical user Interface on LabVIEW.
Figure 20.
Graphical user Interface on LabVIEW showing different levels of sensors.
Figure 21.
Graphical user Interface on LabVIEW showing various levels of air quality.
7. Results
7.1 Arduino based results
The results of air quality monitoring system are displayed on arduino serial monitor window of co-ordinator node, Front Panel of LabVIEW and on Blynk platform through the Android app developed by user’s mobile phone. Arduino based results of air quality monitoring system are as follows. The sensors calibration and its coding are done in arduino IDE. This is shown in Figure 22.
Figure 22.
Arduino coding for air quality monitoring system.
7.2 LabVIEW based results
The LabVIEW front panel will exhibit the responses when the sensor incorporated within the sensor node collects the data within the environment. The threshold frontiers specified for this sensor are according to the OSHA standard. According to the threshold limit, different levels are displayed on the LabVIEW.
The sensors three levels are displayed on the front panel of LabVIEW. These levels are different for different sensors. For temperature sensor, cool level is displayed using green colored LED. Normal level of temperature is displayed using yellow colored LED, while red colored LED shows hot level of temperature. A voltmeter and pollution level meter is given, for easiness of users, to monitor the different pollution level. For CO sensor, Normal level is displayed using green color square LED. Hazardous level of CO is displayed using yellow color square LED, while red color square LED shows risky level of CO. For NOx sensor, normal level is displayed using green colored LED, unhealthy level of NOx is displayed using yellow colored LED, while red colored LED shows hazardous level of NOx. Low level of humidity is displayed using green colored LED. Normal level of humidity is displayed using yellow colored LED, while red colored LED shows high level of humidity. The RSPM levels such as normal, unhealthy and hazardous are displayed using green, yellow and red oval LED’s respectively. The rationale of GUI is to erect the system extra interactive and superficial. The programming structure is shown in Figure 23. The real execution of wireless air quality monitoring system is shown in Figure 24.
Figure 23.
LabVIEW programming structure of air quality monitoring system.
Figure 24.
Actual LabVIEW G-code for air quality monitoring system.
7.3 IoT based result
Internet of things (IoT) based system helps to detect the existing level of perilous gases in the environment. The system assists to obtain the data from any locality where the mechanism is installed. All the data can be perceived in the smartphone app. The present system uses the Blynk app. The relevance for the IoT-based air quality monitoring was evolved to observe the data and be vigilant users. Air quality can be scrutinized together with the web server and with linked smart devices via the application. Monitoring of air quality is effortless and competent using the Blynk App as it provides admittance anytime using smart devices. For IoT enabled system, the user obtains a notice through the Blynk Application on the mobile phone about the detection level of CO, NOx, RSPM, humidity and temperature for the area where the sensor nodes were deployed. An experimental set up for the IoT testing of air quality shown in Figure 25.
Figure 25.
Experimental set-up for the IoT testing of air quality.
In Figure 26, the Blynk application on a mobile phone shows humidity as 20.9%, temperature as 34.17°C, CO as 44 ppm, NOx as 22 ppm and RSPM as 512 μg/m3. These real-time values are sent to the app using internet. A warning is sent to the App for alerting the user that the contamination in air is beyond which can be detrimental for human health. Alerting the users is mandatory to avert an environmental impairment and users can take instantaneously remedial measures.
Figure 26.
Blynk app for air quality monitoring.
8. Conclusions
This chapter describes a Wireless Sensor Network (WSN) based air quality monitoring system for Solapur city using IoT and LabVIEW. An amalgamation of WSN and IoT makes the system more reliable, smart and scalable than the traditional data logger system. A cost-effective, least power and efficient wireless star network based online air quality monitoring scheme is developed that includes temperature, humidity, RSPM, carbon monoxide and nitrous oxide measurements. The system evaluates the contamination level in the public areas. IoT accredits the users to observe the contamination levels of the region where the system is installed. Moreover, LabVIEW diminish the hardware necessity through visual coding. The real-time data on user’s mobile phone can examine to recognize the air quality in the installed area of the system. Due to the use of IoT web platform and XBee wireless protocol, the developed system is less time consuming and less power consuming over to the traditional system.
\n',keywords:"WSN, XBee, Sensor Node, Gateway Node, IoT, Blynk Platform",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/77471.pdf",chapterXML:"https://mts.intechopen.com/source/xml/77471.xml",downloadPdfUrl:"/chapter/pdf-download/77471",previewPdfUrl:"/chapter/pdf-preview/77471",totalDownloads:256,totalViews:0,totalCrossrefCites:0,totalDimensionsCites:0,totalAltmetricsMentions:0,impactScore:0,impactScorePercentile:38,impactScoreQuartile:2,hasAltmetrics:0,dateSubmitted:"April 10th 2021",dateReviewed:"June 7th 2021",datePrePublished:"August 2nd 2021",datePublished:"March 23rd 2022",dateFinished:"July 8th 2021",readingETA:"0",abstract:"Owing to enhancement in technology there is inclination in miniaturization of devices which demands to build up stumpy expensive sensor, least powered and hardy devices. Accordingly, Wireless Sensor Networks (WSN) has gained significance in diverse applications: Farming, household, industries and environmental monitoring. Wireless sensor network system worn to monitor and control the air quality of an environment is developed. The air pollution monitoring system that measures temperature, humidity, SPM (Suspended Particulate Matter), NOx and CO are proposed. The conventional air quality monitoring system, prescribed by the Pollution Control Department, is tremendously pricey. Analytical measuring paraphernalia is lavish, time and power overriding, and can seldom be used for air quality exposure in real time. Endeavor has been completed to develop state of art monitoring system using commercially available standard pollutant gas sensors incorporated into a mote. An exact program made with LabVIEW is formed to constitute the measurements of sensing used in the established network. Remote monitoring of the system is made possible using IoT.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/77471",risUrl:"/chapter/ris/77471",book:{id:"10765",slug:"environmental-management-pollution-habitat-ecology-and-sustainability"},signatures:"Tabbsum Hanif Mujawar, P. Prabhkar, Vijendra Chaudhary and Lalasaheb Deshmukh",authors:[{id:"292284",title:"Dr.",name:"Tabbsum",middleName:"Hanif",surname:"Mujawar",fullName:"Tabbsum Mujawar",slug:"tabbsum-mujawar",email:"thmujawar@sus.ac.in",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/292284/images/8199_n.jpg",institution:null},{id:"300961",title:"Prof.",name:"Lalasaheb",middleName:null,surname:"Deshmukh",fullName:"Lalasaheb Deshmukh",slug:"lalasaheb-deshmukh",email:"laldeshmukh@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"350411",title:"Prof.",name:"P.",middleName:null,surname:"Prabhakar",fullName:"P. Prabhakar",slug:"p.-prabhakar",email:"geoprabhakar@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"414488",title:"Dr.",name:"Vijendra",middleName:null,surname:"Chaudhari",fullName:"Vijendra Chaudhari",slug:"vijendra-chaudhari",email:"vijendra333@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Swami Ramanand Teerth Marathwada University",institutionURL:null,country:{name:"India"}}}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Wireless sensor network setup for air quality monitoring system",level:"1"},{id:"sec_2_2",title:"2.1 Sensor node (mote)",level:"2"},{id:"sec_2_3",title:"2.1.1 CO sensor (MQ-7)",level:"3"},{id:"sec_3_3",title:"2.1.2 Temperature sensor (LM-35)",level:"3"},{id:"sec_4_3",title:"2.1.3 MQ-135(NOx and SPM sensor)",level:"3"},{id:"sec_5_3",title:"2.1.4 Atmega 328 (controlling unit)",level:"3"},{id:"sec_6_3",title:"2.1.5 XBee protocol",level:"3"},{id:"sec_9",title:"3. IoT (internet of things)",level:"1"},{id:"sec_9_2",title:"3.1 Blynk platform",level:"2"},{id:"sec_11",title:"4. LabVIEW",level:"1"},{id:"sec_12",title:"5. Working of the system",level:"1"},{id:"sec_12_2",title:"5.1 Accomplishment of a system to attain a data from sensor node(mote)",level:"2"},{id:"sec_14",title:"6. Comparative analysis of current system with air quality status of Maharashtra 2019–2020 for Solapur City",level:"1"},{id:"sec_15",title:"7. Results",level:"1"},{id:"sec_15_2",title:"7.1 Arduino based results",level:"2"},{id:"sec_16_2",title:"7.2 LabVIEW based results",level:"2"},{id:"sec_17_2",title:"7.3 IoT based result",level:"2"},{id:"sec_19",title:"8. Conclusions",level:"1"}],chapterReferences:[{id:"B1",body:'R.K. Pachauri, P.V. Sridharan, “Looking Back to Think Ahead, Green India 2047: Growth with Resource Enhancement of Environment and Nature”, Energy and Resources Institute, 1998, pp.1-368.'},{id:"B2",body:'Sengupta R, Madal S, “Health damage cost of automotive air pollution: Cost benefit analysis of fuel quality upgradation for Indian cities”, eSocial Sciences, 2005.'},{id:"B3",body:'Gajul M.D. and Mujawar.K.C Prabhakar. P., “Ambient Air Quality in Solapur; A tight rope walk for Solapur citizens”, Indian Society of Geochemistry, 56(2013), pp.1-6.'},{id:"B4",body:'Muthu Bharathi. M, Rajasekaran. M, “Air Quality Monitoring System Using Wireless Sensor Networks”, International Journal of Engineering Research & Technology (IJERT), 6(2018), pp. 1-6.'},{id:"B5",body:'Harsh N. Shah, Zishan Khan, Abbas Ali Merchant, Moin Moghal, Aamir Shaikh, Priti Rane , “IOT Based Air Pollution Monitoring System”, International Journal of Scientific & Engineering Research, 9(2018),pp. 62-66.'},{id:"B6",body:'K. Maraiya, K. Kant and N. Gupta, “Application based Study on Wireless Sensor Network”, International Journal of Computer Applications, 21(2011),pp. 9-15.'},{id:"B7",body:'https://www.sparkfun.com/datasheets/Sensors/Biometric/MQ-7'},{id:"B8",body:'https://www.ti.com/lit/ds/symlink/lm35'},{id:"B9",body:'http://china-total.com/Product/meter/gas-sensor/MQ135'},{id:"B10",body:'Margolis, Michael, Arduino Cookbook, Ed. 1, O’REILLY® Media, Inc., March 2011, pp. 81-213.'},{id:"B11",body:'XBee/XBee-Pro OEM RF Modules, Maxstream, Inc., Lindon, UT, 2007.'},{id:"B12",body:'M. Benammar, A. Abdaoui, S. Ahmad, F. Touati, and A. Kadri, “A modular IoT platform for real-time indoor air quality monitoring,” Sensors, 18 (2018), pp. 581.'},{id:"B13",body:'Y. J. Fan, Y. H. Yin, L. D. Xu, Y. Zeng, and F. Wu, “IoT-based smart rehabilitation system,” IEEE Transactions on Industrial Informatics, 10 (2014) , pp. 1568–1577.'},{id:"B14",body:'Rucha Golwalkar1, Kajal Shivgan2, Parul Sindhwad3*,” Pollution Monitoring System Using IoT and LabVIEW”, International Journal for Research in Engineering Application & Management, 06(2020), pp.184-188.'},{id:"B15",body:'Bitter, Rick, T. Mohiuddin and M. Narocki “LabVIEW Advanced Programming Techniques “Boca Raton: CRC Press LLC, 2001'},{id:"B16",body:'T.H. Mujawar, V.D. Bachuwar, M.S.Kasbe, A. D. Shaligram, L.P. Deshmukh “Development of wireless sensor network system for LPG gas leakage detection system”, International Journal of Scientific & Engineering Research, 6(2015) 558-563.'},{id:"B17",body:'Bansode. P. B Mujawar. K. C Prabhakar. P.,” An Insight into the Unseen: A Case Study of Ambient Air Quality in Solapur City, Maharashtra, India”, Jour. Of Environ. Geochem.,15(2012), pp.43-46.'},{id:"B18",body:'P Prabhakar, MD Gajul, NT Chavan, “Air affair in the proposed smart city of Solapur–a case study”, Journal of Applied Geochemistry, 20(2018), pp.466-473.'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Tabbsum Hanif Mujawar",address:"thmujawar@sus.ac.in",affiliation:'
School of Physical Sciences, P.A.H. Solapur University, India
Department of Electronic Science, Savitribai Phule Pune University, India
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1. Principle of magnetron sputtering
Sputter deposition is a physical vapor deposition (PVD) method of thin film deposited by sputtering. The general sputtering method can be used to prepare a variety of materials such as metals, semiconductors, insulators, etc., and has the advantages of simple equipment, easy control, large coating area, and strong adhesion, and the magnetron sputtering method developed in the 1970s achieves high speed, low temperature, and low damage.
Adding a closed magnetic field parallel to the target surface in the bipolar sputtering, the secondary electron is bound to a specific area of the target surface to enhance the ionization efficiency by means of the orthogonal electromagnetic field formed on the surface of the target, increasing the ion density and energy, and finally realizing the high-rate sputtering. The above statement is the concept of magnetron sputtering.
Magnetron sputtering is a dominant technique to grow thin films because a large quantity of thin films can be prepared at relatively high purity and low cost. This involves ejecting material from a “target” that is a source onto a “substrate” such as a silicon wafer, as shown in Figure 1.
Figure 1.
Schematic diagram of magnetron sputtering.
Magnetron sputtering is the collision process between incident particles and targets. Since high-speed sputtering is performed at a low pressure, it is necessary to effectively increase the ionization rate of the gas. The incident particle undergoes a complex scattering process in the target, collides with the target atom, and transmits part of the momentum to the target atom, which in turn collides with other target atoms to form a cascade process. During this cascade, certain target atoms near the surface gain sufficient momentum for outward motion and are sputtered out of the target. Magnetron sputtering increases the plasma density by introducing a magnetic field on the surface of the target cathode and utilizing the constraints of the magnetic field on the charged particles to increase the sputtering rate.
Magnetron sputtering includes many types, such as direct current (DC) magnetron sputtering and radio frequency (RF) magnetron sputtering, each has a different working principle and application objects. The main advantage of RF magnetron sputtering over DC magnetron sputtering is that it does not require the target as an electrode be electrically conductive. Therefore, any material can be sputter-deposited theoretically using RF magnetron sputtering.
But there is one thing in common for any type of magnetron sputtering: the interaction between the magnetic field and the electric field causes the electrons to spiral in the vicinity of the target surface, thereby increasing the probability that electrons will strike the argon gas to generate ions. The generated ions collide with the target surface under the action of an electric field to sputter the target. The target source is divided into balanced and unbalanced types; the balanced target source is uniformly coated, and the unbalanced target coating layer and the substrate have strong bonding force.
Balanced target sources are mostly used in semiconductor optical films, and unbalanced are mostly used in wear decorative films. Sputtering metals and alloys with a magnetron target is easy, and it is convenient for ignition and sputtering. Magnetron reactive sputtering insulators appear to be easy, but it is difficult for practical operations.
The magnetron cathodes are roughly classified into an equilibrium state and an unbalanced magnetron cathode according to the distribution of the magnetic field configuration. Cooling is necessary for all sources (magnetron, multiarc, ion) because a large part of the energy is converted to heat. If there is no cooling or insufficient cooling, this heat will cause the target temperature to reach more than 1000°C to dissolve the entire target.
2. Applications of magnetron sputtering
Main uses of magnetron sputtering are the following:
Various functional films: such as films having absorption, transmission, reflection, refraction, polarization, and so on. For example, a silicon nitride antireflection film is deposited at a low temperature to improve the photoelectric conversion efficiency of the solar cell.
Applications in the field of decoration, such as various total reflection films and translucent films, such as cell phone cases, mice, etc.
As a nonthermal coating technology in the field of microelectronics, mainly used in chemical vapor deposition (CVD) or metal organics.
Chemical vapor deposition (MOCVD) growth is difficult and unsuitable material film deposition, and a very uniform film of a large area can be obtained.
In the field of optics: if closed-field unbalanced magnetron sputtering technology has also been applied in optical films (such as antireflection film), low-emissivity glass, and transparent conductive glass. In particular, transparent conductive glass is widely used in flat panel display devices, solar cells, microwave and RF shielding devices, and devices, sensors, and the like.
In the machining industry, the surface deposition technology of surface functional film, super hard film, and self-lubricating film has been developed since its inception, which can effectively improve surface hardness, composite toughness, wear resistance, and high temperature chemical stability. Performance greatly increases the service life of coated products.
In addition to the abovementioned fields that have been widely used, magnetron sputtering plays an important role in the research of high-temperature superconducting thin films, ferroelectric thin films, giant magnetoresistive thin films, thin film luminescent materials, solar cells, and memory alloy thin films.
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If your research is financed through any of the below-mentioned funders, please consult their Open Access policies or grant ‘terms and conditions’ to explore ways to cover your publication costs (also accessible by clicking on the link in their title).
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IMPORTANT: You must be a member or grantee of the listed funders in order to apply for their Open Access publication funds. Do not attempt to contact the funders if this is not the case.
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UK Research and Innovation (former Research Councils UK (RCUK) - including AHRC, BBSRC, ESRC, EPSRC, MRC, NERC, STFC.) Processing charges for books/book chapters can be covered through RCUK block grants which are allocated to most universities in the UK, which then handle the OA publication funding requests. It is at the discretion of the university whether it will approve the request.)
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Laser based thin film deposition techniques such as pulsed laser deposition or matrix-assisted pulsed laser evaporation (MAPLE) are competing with conventional methods for integrating new materials with tailored properties for novel technological developments. Successful polymer and protein thin film deposition requires several key elements for depositing viable and functional thin films, i.e. the characteristics of the laser depositing system, the choice of targets and receiver substrates, etc. This chapter reviews the following topics: brief presentation of the MAPLE process including several examples of polymer materials deposited by MAPLE, thus illustrating the potential of the technique as a gentle laser-assisted deposition method. In particular, the “synthesis” of new materials, their analysis and correlation of the bulk and interface properties to its bio-environment shall be discussed as a method to tackle some bioengineering issues. We will also focus on recent breakthroughs of the MAPLE technique for the fabrication of functional devices, i.e. sensor devices based either on chemoresponsive polymers or on proteins.",book:{id:"6059",slug:"laser-ablation-from-fundamentals-to-applications",title:"Laser Ablation",fullTitle:"Laser Ablation - From Fundamentals to Applications"},signatures:"Alexandra Palla Papavlu, Valentina Dinca, Mihaela Filipescu and\nMaria Dinescu",authors:[{id:"32241",title:"Dr.",name:"Maria",middleName:null,surname:"Dinescu",slug:"maria-dinescu",fullName:"Maria Dinescu"},{id:"176781",title:"Dr.",name:"Valentina",middleName:null,surname:"Dinca",slug:"valentina-dinca",fullName:"Valentina Dinca"},{id:"206985",title:"Ph.D.",name:"Alexandra",middleName:null,surname:"Palla Papavlu",slug:"alexandra-palla-papavlu",fullName:"Alexandra Palla Papavlu"},{id:"207048",title:"Dr.",name:"Mihaela",middleName:null,surname:"Filipescu",slug:"mihaela-filipescu",fullName:"Mihaela Filipescu"}]},{id:"24748",doi:"10.5772/24134",title:"Deconvolution of Long-Pulse Lidar Profiles",slug:"deconvolution-of-long-pulse-lidar-profiles",totalDownloads:2164,totalCrossrefCites:0,totalDimensionsCites:9,abstract:null,book:{id:"1356",slug:"lasers-applications-in-science-and-industry",title:"Lasers",fullTitle:"Lasers - Applications in Science and Industry"},signatures:"Ljuan L. Gurdev, Tanja N. Dreischuh and Dimitar V. Stoyanov",authors:[{id:"55686",title:"Dr.",name:"Ljuan",middleName:null,surname:"Gurdev",slug:"ljuan-gurdev",fullName:"Ljuan Gurdev"},{id:"61273",title:"Dr.",name:"Tanja",middleName:null,surname:"Dreischuh",slug:"tanja-dreischuh",fullName:"Tanja Dreischuh"},{id:"61274",title:"Prof.",name:"Dimitar",middleName:"Vassilev",surname:"Stoyanov",slug:"dimitar-stoyanov",fullName:"Dimitar Stoyanov"}]},{id:"24745",doi:"10.5772/24024",title:"Laser Pulse Application in IVF",slug:"laser-pulse-application-in-ivf",totalDownloads:4055,totalCrossrefCites:7,totalDimensionsCites:9,abstract:null,book:{id:"1356",slug:"lasers-applications-in-science-and-industry",title:"Lasers",fullTitle:"Lasers - Applications in Science and Industry"},signatures:"Carrie Bedient, Pallavi Khanna and Nina Desai",authors:[{id:"55004",title:"Dr.",name:"Nina",middleName:null,surname:"Desai",slug:"nina-desai",fullName:"Nina Desai"},{id:"127713",title:"Dr.",name:"Carrie",middleName:null,surname:"Bedient",slug:"carrie-bedient",fullName:"Carrie Bedient"},{id:"127714",title:"Dr.",name:"Pallavi",middleName:null,surname:"Khanna",slug:"pallavi-khanna",fullName:"Pallavi Khanna"}]},{id:"68795",doi:"10.5772/intechopen.88860",title:"Preparation, Characterization, and Applications of Carbonaceous Mesophase: A Review",slug:"preparation-characterization-and-applications-of-carbonaceous-mesophase-a-review",totalDownloads:1350,totalCrossrefCites:5,totalDimensionsCites:9,abstract:"Carbonaceous mesophase with a nematic liquid crystal structure possesses an easily graphitizable characteristic and can be used as a promising raw material to prepare anisotropic carbon and graphite materials with high performance and multifunction. Therefore, the carbonaceous mesophase occupies a pivotal and irreplaceable position in many frontier and cutting-edge fields. The controllable preparation and characterization of carbonaceous mesophase derived from a model molecule (i.e., naphthalene) are presented, especially the formation, development, and transformation of anisotropic liquid crystalline mesophase in the synthetic naphthalene pitch during the process of liquid-phase carbonization (350–450°C). The increasing applications of naphthalene-based carbonaceous mesophase as an ideal precursor material for fabricating representative advanced carbon materials with high added value (e.g., mesophase pitch-derived coke, mesocarbon microbeads, mesophase pitch-based carbon foam, high-modulus mesophase pitch-based carbon fibers, and high-thermal-conductivity carbon-based composites, etc.) are reviewed in detail in this chapter.",book:{id:"7965",slug:"liquid-crystals-and-display-technology",title:"Liquid Crystals and Display Technology",fullTitle:"Liquid Crystals and Display Technology"},signatures:"Guanming Yuan and Zhengwei Cui",authors:[{id:"308403",title:"Prof.",name:"Guanming",middleName:null,surname:"Yuan",slug:"guanming-yuan",fullName:"Guanming Yuan"},{id:"309210",title:"Dr.",name:"Zhengwei",middleName:null,surname:"Cui",slug:"zhengwei-cui",fullName:"Zhengwei Cui"}]},{id:"24737",doi:"10.5772/24285",title:"Production of Optical Coatings Resistant to Damage by Petawatt Class Laser Pulses",slug:"production-of-optical-coatings-resistant-to-damage-by-petawatt-class-laser-pulses",totalDownloads:3245,totalCrossrefCites:4,totalDimensionsCites:8,abstract:null,book:{id:"1356",slug:"lasers-applications-in-science-and-industry",title:"Lasers",fullTitle:"Lasers - Applications in Science and Industry"},signatures:"John Bellum, Patrick Rambo, Jens Schwarz, Ian Smith, Mark Kimmel, Damon Kletecka and Briggs Atherton",authors:[{id:"56477",title:"Dr.",name:"John",middleName:"C.",surname:"Bellum",slug:"john-bellum",fullName:"John Bellum"},{id:"120423",title:"Dr.",name:"Patrick",middleName:null,surname:"Rambo",slug:"patrick-rambo",fullName:"Patrick Rambo"},{id:"120424",title:"Dr.",name:"Jens",middleName:null,surname:"Schwarz",slug:"jens-schwarz",fullName:"Jens Schwarz"},{id:"120425",title:"Mr.",name:"Ian",middleName:null,surname:"Smith",slug:"ian-smith",fullName:"Ian Smith"},{id:"120426",title:"Mr.",name:"Mark",middleName:null,surname:"Kimmel",slug:"mark-kimmel",fullName:"Mark Kimmel"},{id:"120427",title:"Mr.",name:"Damon",middleName:null,surname:"Kletecka",slug:"damon-kletecka",fullName:"Damon Kletecka"},{id:"120428",title:"Dr.",name:"Briggs",middleName:null,surname:"Atherton",slug:"briggs-atherton",fullName:"Briggs Atherton"}]}],mostDownloadedChaptersLast30Days:[{id:"71926",title:"An Overview of Polymer-Dispersed Liquid Crystals Composite Films and Their Applications",slug:"an-overview-of-polymer-dispersed-liquid-crystals-composite-films-and-their-applications",totalDownloads:1185,totalCrossrefCites:2,totalDimensionsCites:4,abstract:"Inherent and incredible properties of liquid crystals (LC) such as optical and dielectric anisotropy make them special candidates for flat-panel display devices; bi-stable reflective displays; high-definition spatial light modulators; switchable windows; haze-free normal- and reverse-mode light shutter devices; projectors; optical, thermal and strain sensors; tuneable lenses; etc. Non-linear response of LC material to the applied electric field is very useful in the above-mentioned applications. When a low molecular weight LC material is doped in a high molecular weight polymer matrix to obtain polymer-dispersed liquid crystal (PDLC) films, it offers flexibility and mechanical strength (structural stabilization) to the composite films—PDLC devices. Depending upon the concentration of monomer/polymer, these composite films are classified as polymer-stabilized liquid crystal (PSLC), PDLC and holographic PDLC (HPDLC) films. Depending upon the process conditions, we get phase-separated randomly dispersed micron-sized LC droplets in a continuous polymer matrix. These nematic LC droplets exhibit light scattering transmission properties depending on their orientation, which can be controlled by external electric field. This chapter gives deep insight about operating principle, phase separation techniques involved, alignment of LC and controlling LC droplet morphology of PDLC films to obtain desired properties. In order to improve the optical efficiency and to obtain the desired result from PDLC films, various guest entities such as dye and nanomaterials are doped in the host LC material. This chapter also accounts for various possible LC dopants desired for improving the electro-optic (EO) and dielectric properties of PDLC devices. Various applications of PDLC composite films are also described in this chapter.",book:{id:"7965",slug:"liquid-crystals-and-display-technology",title:"Liquid Crystals and Display Technology",fullTitle:"Liquid Crystals and Display Technology"},signatures:"Anuja Katariya Jain and Rajendra R. Deshmukh",authors:[{id:"34437",title:"Dr.",name:"Rajendrasing",middleName:"Rajesing",surname:"Deshmukh",slug:"rajendrasing-deshmukh",fullName:"Rajendrasing Deshmukh"},{id:"318245",title:"Dr.",name:"Anuja",middleName:null,surname:"Katariya-Jain",slug:"anuja-katariya-jain",fullName:"Anuja Katariya-Jain"}]},{id:"71353",title:"Cholesteric Liquid Crystal Polyesteramides: Non-Viral Vectors",slug:"cholesteric-liquid-crystal-polyesteramides-non-viral-vectors",totalDownloads:597,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"Polyesteramides PNOBDME (C34H38N2O6)n, Poly[oxy(1,2-dodecane)-oxy-carbonyl-1,4-phenylene-amine-carbonyl-1,4-phenylene-carbonyl-amine-1,4-phenylene-carbonyl], and PNOBEE (C26H22N2O6)n, Poly[oxy(1,2-butylene)-oxy-carbonyl-1,4-phenylene-amine-carbonyl-1,4-phenylene-carbonyl-amine-1,4-phenylene-carbonyl], have been designed and synthesized as cholesteric liquid crystals (LCs)—through a condensation reaction between 4- 4′-(terephthaloyl-diaminedibenzoic chloride) (NOBC) and racemic glycol, DL-1,2-dodecanediol or DL-1,2-butanediol, respectively—as chemical modifications of multifunctional cholesteric LC polyesters, involving new properties but holding the precursor helical macromolecular structures. The new compounds have been characterized by 1H and 13C-NMR, COSY and HSQC, exhibiting two 1H-independent sets of signals observed for each enantiomer, attributed to two diastereomeric conformers, gg and gt, of the torsion containing the asymmetric carbon atom in the spacer. They have also been characterized by x-ray diffraction with synchrotron radiation source. Thermal behaviour of the new compounds is studied by thermogravimetric (TG) and differential scanning calorimetry (DSC) analysis. The substitution of the ester groups in the mesogen by amide groups causes an increase of thermal stability with respect to the precursors. Optical rotatory dispersion (ORD) is evaluated. Morphology of powdered PNOBDME exhibits spherical clusters of about 5 μm in diameter homogeneously dispersed. Molecular models show helical polymeric chains with stereoregular head-tail, isotactic structure, explained as due to the higher reactivity of the primary hydroxyl with respect to the secondary one in the glycol through the polycondensation reaction. Besides being biocompatible, these synthetic polyesteramides have proved to act as non-viral vectors in gene therapy and be able to transfect DNA to the nucleus cell. Similar new cationic cholesteric liquid crystal polyesters have also been synthesized in our laboratory.",book:{id:"7965",slug:"liquid-crystals-and-display-technology",title:"Liquid Crystals and Display Technology",fullTitle:"Liquid Crystals and Display Technology"},signatures:"Mercedes Pérez Méndez and José Fayos Alcañiz",authors:[{id:"205972",title:"Dr.",name:"Mercedes",middleName:null,surname:"Pérez Méndez",slug:"mercedes-perez-mendez",fullName:"Mercedes Pérez Méndez"},{id:"316150",title:"Prof.",name:"José",middleName:null,surname:"Fayos Alcañíz",slug:"jose-fayos-alcaniz",fullName:"José Fayos Alcañíz"}]},{id:"72382",title:"Introductory Chapter: Nematic Liquid Crystals",slug:"introductory-chapter-nematic-liquid-crystals",totalDownloads:657,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"7965",slug:"liquid-crystals-and-display-technology",title:"Liquid Crystals and Display Technology",fullTitle:"Liquid Crystals and Display Technology"},signatures:"Irina Carlescu",authors:[{id:"258032",title:"Prof.",name:"Irina",middleName:null,surname:"Carlescu",slug:"irina-carlescu",fullName:"Irina Carlescu"}]},{id:"57062",title:"Optical Properties of Complex Oxide Thin Films Obtained by Pulsed Laser Deposition",slug:"optical-properties-of-complex-oxide-thin-films-obtained-by-pulsed-laser-deposition",totalDownloads:1527,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The market for thin films of complex oxides obtained by different deposition techniques is increasing exponentially in last decades due to large variety of possible application such as high-efficient solar cell, optoelectronic devices, etc. pulsed laser deposition (PLD) is a versatile growth technique and recently became more attractive for industrial applications due to the possibility to obtain crystalline thin films on a large area. Laser processing techniques were successfully used to obtain thin films with good optical properties starting from simple oxides, such as Sm2O3, ZrO2, etc., to more complex lead-free materials: SrxBa1−xNb2O6 (SBN) and Na1/2Bi1/2TiO3−x%BaTiO3, or superconductive oxide YBa2Cu3O7−δ. When oxide thin films are designated for electronic and optoelectronic devices or for solar cells, the optical properties and the thickness must be well known. For this purpose, the spectroscopic ellipsometry technique was developed. Ellipsometry is a powerful technique to determine the optical properties of thin films especially when the thicknesses of thin films are in a nanometer range.",book:{id:"6059",slug:"laser-ablation-from-fundamentals-to-applications",title:"Laser Ablation",fullTitle:"Laser Ablation - From Fundamentals to Applications"},signatures:"Valentin Ion, Andreea Andrei, Maria Dinescu and Nicu Doinel\nScarisoreanu",authors:[{id:"32241",title:"Dr.",name:"Maria",middleName:null,surname:"Dinescu",slug:"maria-dinescu",fullName:"Maria Dinescu"},{id:"156567",title:"MSc.",name:"Andreea",middleName:null,surname:"Andrei",slug:"andreea-andrei",fullName:"Andreea Andrei"},{id:"181341",title:"Dr.",name:"Valentin",middleName:null,surname:"Ion",slug:"valentin-ion",fullName:"Valentin Ion"},{id:"181362",title:"Dr.",name:"Nicu D.",middleName:null,surname:"Scarisoreanu",slug:"nicu-d.-scarisoreanu",fullName:"Nicu D. Scarisoreanu"}]},{id:"56891",title:"Multi-Beam Multi-Target Pulsed Laser Deposition of AZO Films with Polymer Nanoparticles for Thermoelectric Energy Harvesters",slug:"multi-beam-multi-target-pulsed-laser-deposition-of-azo-films-with-polymer-nanoparticles-for-thermoel",totalDownloads:1389,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"In comparison with metallic thermoelectric films, oxide films with artificial nanodefects have been seldom studied. And there has been no report on the incorporation of island-shaped organic nanoparticles. We describe a new approach to introduce nanometer-sized phonon scatterers in aluminum-doped ZnO (AZO) thermoelectric thin films–concurrent multi-beam multi-target-pulsed laser deposition and the matrix-assisted pulsed laser evaporation (MBMT-PLD/MAPLE). The approach was used to make nanocomposite thin films of AZO matrix with evenly dispersed poly(methyl methacrylate) (PMMA) nanoparticles. The introduction of the nanoparticles enhanced phonon scattering with consequent decrease of thermal conductivity by 20%. The electrical conductivity did not decrease after the addition of the second phase, as it would be predicted by Wiedemann-Franz law, but improved by 350% over pure AZO film. The thermoelectric figure of merit of the nanocomposite film became twice that of the pure AZO film. Taking advantage of room-temperature deposition, optimized AZO nanocomposite films are expected to be used in real applications, such as thin film modules deposited on flexible polymeric substrates for ubiquitous harvesting of the waste heat.",book:{id:"6059",slug:"laser-ablation-from-fundamentals-to-applications",title:"Laser Ablation",fullTitle:"Laser Ablation - From Fundamentals to Applications"},signatures:"Abdalla M. Darwish, Sergey S. Sarkisov, Paolo Mele and Shrikant\nSaini",authors:[{id:"186848",title:"Prof.",name:"Abdalla",middleName:null,surname:"Darwish",slug:"abdalla-darwish",fullName:"Abdalla Darwish"},{id:"212023",title:"Dr.",name:"Sergey",middleName:null,surname:"Sarkisov",slug:"sergey-sarkisov",fullName:"Sergey Sarkisov"},{id:"217105",title:"Dr.",name:"Paolo",middleName:null,surname:"Mele",slug:"paolo-mele",fullName:"Paolo Mele"},{id:"217106",title:"Dr.",name:"Shrikant",middleName:null,surname:"Saini",slug:"shrikant-saini",fullName:"Shrikant Saini"}]}],onlineFirstChaptersFilter:{topicId:"1222",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:8,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:286,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:105,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:9,numberOfPublishedChapters:101,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"May 15th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:27,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:48,paginationItems:[{id:"81799",title:"Cross Talk of Purinergic and Immune Signaling: Implication in Inflammatory and Pathogenic Diseases",doi:"10.5772/intechopen.104978",signatures:"Richa Rai",slug:"cross-talk-of-purinergic-and-immune-signaling-implication-in-inflammatory-and-pathogenic-diseases",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81764",title:"Involvement of the Purinergic System in Cell Death in Models of Retinopathies",doi:"10.5772/intechopen.103935",signatures:"Douglas Penaforte Cruz, Marinna Garcia Repossi and Lucianne Fragel Madeira",slug:"involvement-of-the-purinergic-system-in-cell-death-in-models-of-retinopathies",totalDownloads:2,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81756",title:"Alteration of Cytokines Level and Oxidative Stress Parameters in COVID-19",doi:"10.5772/intechopen.104950",signatures:"Marija Petrusevska, Emilija Atanasovska, Dragica Zendelovska, Aleksandar Eftimov and Katerina Spasovska",slug:"alteration-of-cytokines-level-and-oxidative-stress-parameters-in-covid-19",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}},{id:"81681",title:"Immunomodulatory Effects of a M2-Conditioned Medium (PRS® CK STORM): Theory on the Possible Complex Mechanism of Action through Anti-Inflammatory Modulation of the TLR System and the Purinergic System",doi:"10.5772/intechopen.104486",signatures:"Juan Pedro Lapuente",slug:"immunomodulatory-effects-of-a-m2-conditioned-medium-prs-ck-storm-theory-on-the-possible-complex-mech",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}}]},overviewPagePublishedBooks:{paginationCount:27,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. Waisundara",profilePictureURL:"https://mts.intechopen.com/storage/users/194281/images/system/194281.jpg",biography:"Dr. Viduranga Waisundara obtained her Ph.D. in Food Science and Technology from the Department of Chemistry, National University of Singapore, in 2010. She was a lecturer at Temasek Polytechnic, Singapore from July 2009 to March 2013. She relocated to her motherland of Sri Lanka and spearheaded the Functional Food Product Development Project at the National Institute of Fundamental Studies from April 2013 to October 2016. She was a senior lecturer on a temporary basis at the Department of Food Technology, Faculty of Technology, Rajarata University of Sri Lanka. She is currently Deputy Principal of the Australian College of Business and Technology – Kandy Campus, Sri Lanka. 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University, Kuwait. 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He is also an editor and editor in chief for various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:null},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:"Beijing University of Technology",institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Lakhno Igor Victorovich was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPhD – 1999, Kharkiv National Medical Univesity.\nDSc – 2019, PL Shupik National Academy of Postgraduate Education \nLakhno Igor has been graduated from an international training courses on reproductive medicine and family planning held in Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor of the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s a professor of the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education . He’s an author of about 200 printed works and there are 17 of them in Scopus or Web of Science databases. Lakhno Igor is a rewiever of Journal of Obstetrics and Gynaecology (Taylor and Francis), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for DSc degree \\'Pre-eclampsia: prediction, prevention and treatment”. Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: obstetrics, women’s health, fetal medicine, cardiovascular medicine.",institutionString:"V.N. Karazin Kharkiv National University",institution:{name:"Kharkiv Medical Academy of Postgraduate Education",country:{name:"Ukraine"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"243698",title:"M.D.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:"Shanxi Eye Hospital",institution:{name:"Shanxi Eye Hospital",country:{name:"China"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRZkkQAG/Profile_Picture_2022-05-09T12:55:18.jpg",biography:null,institutionString:null,institution:null},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. 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Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. 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Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. 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