CI categories and components modeled in the case study.
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Barely three months into the new year and we are happy to announce a monumental milestone reached - 150 million downloads.
\n\nThis achievement solidifies IntechOpen’s place as a pioneer in Open Access publishing and the home to some of the most relevant scientific research available through Open Access.
\n\nWe are so proud to have worked with so many bright minds throughout the years who have helped us spread knowledge through the power of Open Access and we look forward to continuing to support some of the greatest thinkers of our day.
\n\nThank you for making IntechOpen your place of learning, sharing, and discovery, and here’s to 150 million more!
\n\n\n\n\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"6262",leadTitle:null,fullTitle:"Post Mortem Examination and Autopsy - Current Issues From Death to Laboratory Analysis",title:"Post Mortem Examination and Autopsy",subtitle:"Current Issues From Death to Laboratory Analysis",reviewType:"peer-reviewed",abstract:"Forensic medicine explores the legal aspects of medicine, and medicolegal investigation of death is the most significant and crucial function of it. The nature of post mortem examinations are changing and the understanding of causes of death are evolving with the increase of knowledge, availability, and use of various analyses including genetic testing. Postmortem examination practice is turning into a more multidisciplinary approach for investigations, which are becoming more evidence based. Although there are numerous publications about forensic medicine and post mortem examination, this book aims to provide some basic information on post mortem examination and current developments in some important and special areas. It is considered that this book will be useful for forensic pathologists, clinicians, attorneys, law enforcement officers, and medical students.",isbn:"978-953-51-3793-1",printIsbn:"978-953-51-3792-4",pdfIsbn:"978-953-51-4074-0",doi:"10.5772/intechopen.68970",price:119,priceEur:129,priceUsd:155,slug:"post-mortem-examination-and-autopsy-current-issues-from-death-to-laboratory-analysis",numberOfPages:182,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"fce869ae396986e202a78883a0b1045f",bookSignature:"Kamil Hakan Dogan",publishedDate:"February 14th 2018",coverURL:"https://cdn.intechopen.com/books/images_new/6262.jpg",numberOfDownloads:15306,numberOfWosCitations:9,numberOfCrossrefCitations:7,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:14,numberOfDimensionsCitationsByBook:0,hasAltmetrics:1,numberOfTotalCitations:30,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"May 16th 2017",dateEndSecondStepPublish:"June 6th 2017",dateEndThirdStepPublish:"September 2nd 2017",dateEndFourthStepPublish:"December 1st 2017",dateEndFifthStepPublish:"January 30th 2018",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"30612",title:"Prof.",name:"Kamil Hakan",middleName:null,surname:"Dogan",slug:"kamil-hakan-dogan",fullName:"Kamil Hakan Dogan",profilePictureURL:"https://mts.intechopen.com/storage/users/30612/images/system/30612.jpg",biography:"Kamil Hakan Dogan MD, PhD is a Full Professor and Chair in the Department of Forensic Medicine at Selcuk University, Faculty of Medicine in Turkey. Dr. Dogan received his MD from Gazi University, Faculty of Medicine in 2000. After his extensive research in the forensic medicine field, he received his PhD in Biochemistry in 2012. He gives lectures on Forensic Medicine and Medical Ethics to medical students as well as students of the dentistry and law faculties. He is the editor of five books and Bulletin of Legal Medicine, a reviewer for several international journals and he has published over 200 articles in refereed journals, chapters in textbooks and abstracts in scientific meetings. His publications have been cited more than 900 times.",institutionString:"Selçuk University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"4",totalChapterViews:"0",totalEditedBooks:"3",institution:{name:"Selçuk University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1019",title:"Forensic Science",slug:"forensic-science"}],chapters:[{id:"58754",title:"Introductory Chapter: An Overview of Post-Mortem Examination and Autopsy",doi:"10.5772/intechopen.73279",slug:"introductory-chapter-an-overview-of-post-mortem-examination-and-autopsy",totalDownloads:1631,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:null,signatures:"Kamil Hakan Dogan and Serafettin Demirci",downloadPdfUrl:"/chapter/pdf-download/58754",previewPdfUrl:"/chapter/pdf-preview/58754",authors:[{id:"30612",title:"Prof.",name:"Kamil Hakan",surname:"Dogan",slug:"kamil-hakan-dogan",fullName:"Kamil Hakan Dogan"}],corrections:null},{id:"57547",title:"The Advancement of Postmortem Investigations in Sudden Cardiac Death",doi:"10.5772/intechopen.71555",slug:"the-advancement-of-postmortem-investigations-in-sudden-cardiac-death",totalDownloads:1460,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:1,abstract:"Sudden cardiac death (SCD) is a major public health issue accounting for 15–20% of all-cause deaths. Several pathologies have been associated with sudden cardiac arrest. Clinical autopsies have always contributed to invention of novel strategies for SCD prevention. One of the serious challenges that pathologists are facing is the significant decline of the overall autopsy rate. Many reasons have been associated with this change, most importantly, the evolution process in the postmortem investigation tools. However, cardiologists seem unsatisfied with the new non-invasive imaging techniques and still believe in the traditional autopsy as a gold standard in diagnosis of cardiovascular diseases. In this chapter, we focused on the importance of autopsy in the prevention of SCD by shedding a light on guidelines of minimum requirement for routine autopsy investigation of SCD (including macroscopic, histological, toxicological and molecular examination). We also gave insight into the new radiological techniques, their advantages and related diagnostic pitfalls as compared to that of conventional autopsy. Thus, providing a comprehensive understanding on the advancement of postmortem examination will help improve the minimum standards of routine autopsy practice, develop new guidelines for radiological examination and prevent the growing heterogeneity of the pathologies underlying SCD.",signatures:"Kawthar Braysh, Raymond Zerbe, Rosalyn Jurjus Zein, Doureid\nOueidat, Jihad Hawi, Luk Oke and Abdo Jurjus",downloadPdfUrl:"/chapter/pdf-download/57547",previewPdfUrl:"/chapter/pdf-preview/57547",authors:[{id:"63795",title:"Prof.",name:"Abdo",surname:"Jurjus",slug:"abdo-jurjus",fullName:"Abdo Jurjus"},{id:"220534",title:"Dr.",name:"Kawthar",surname:"Braysh",slug:"kawthar-braysh",fullName:"Kawthar Braysh"},{id:"220535",title:"Dr.",name:"Raymond",surname:"Zerbe",slug:"raymond-zerbe",fullName:"Raymond Zerbe"},{id:"220536",title:"Dr.",name:"Rosalyn",surname:"Jurjus Zein",slug:"rosalyn-jurjus-zein",fullName:"Rosalyn Jurjus Zein"},{id:"220537",title:"Dr.",name:"Jihad",surname:"Hawi",slug:"jihad-hawi",fullName:"Jihad Hawi"},{id:"220539",title:"Dr.",name:"Doureid",surname:"Oueidat",slug:"doureid-oueidat",fullName:"Doureid Oueidat"},{id:"220540",title:"Dr.",name:"Luc",surname:"Oke",slug:"luc-oke",fullName:"Luc Oke"}],corrections:null},{id:"57199",title:"Negative Autopsy in Infant and Juvenile Population: Role of Cardiac Arrhythmias",doi:"10.5772/intechopen.71042",slug:"negative-autopsy-in-infant-and-juvenile-population-role-of-cardiac-arrhythmias",totalDownloads:1417,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"Negative autopsy is a post-mortem examination in which a comprehensive analysis does not provide a cause of death. These include situation of death, anatomical and histological analysis, toxicology and microbiological study. A low part of autopsies remain without a conclusive cause of death, but all these cases are usually seen in young population, apparently healthy who died suddenly and unexpectedly. In these situations a cardiac arrhythmia is suspected as cause of death and genetic testing is recommended despite not regularly performed. Sudden death is a natural and unexpected decease that occurs in apparently healthy people, or whose disease was not severe enough to expect a fatal outcome. It can be due to several pathologies, usually of cardiac cause and called sudden cardiac death. In infants and young people, both long QT syndrome and catecholaminergic polymorphic ventricular tachycardia are main causes in negative autopsies. These genetic diseases lead to ventricular fibrillation, syncope and sudden cardiac death in a normal heart. Unfortunately, sudden cardiac death could be the first manifestation of the diseases, being early identification and prevention a crucial point in current medical practice. This chapter focuses on sudden death and negative autopsy in young population, mainly due to cardiac arrhythmias.",signatures:"Georgia Sarquella-Brugada, Sergi Cesar, Anna Fernandez-Falgueras,\nMaria Dolores Zambrano, Anna Iglesias, Josep Brugada, Ramon\nBrugada and Oscar Campuzano",downloadPdfUrl:"/chapter/pdf-download/57199",previewPdfUrl:"/chapter/pdf-preview/57199",authors:[{id:"54165",title:"Prof.",name:"Ramon",surname:"Brugada",slug:"ramon-brugada",fullName:"Ramon Brugada"},{id:"54168",title:"Dr.",name:"Oscar",surname:"Campuzano",slug:"oscar-campuzano",fullName:"Oscar Campuzano"},{id:"218478",title:"Dr.",name:"Georgia",surname:"Sarquella-Brugada",slug:"georgia-sarquella-brugada",fullName:"Georgia Sarquella-Brugada"},{id:"218479",title:"Dr.",name:"Sergi",surname:"Cesar",slug:"sergi-cesar",fullName:"Sergi Cesar"},{id:"218480",title:"MSc.",name:"Anna",surname:"Fernandez-Falgueras",slug:"anna-fernandez-falgueras",fullName:"Anna Fernandez-Falgueras"},{id:"218482",title:"Dr.",name:"Maria Dolores",surname:"Zambrano",slug:"maria-dolores-zambrano",fullName:"Maria Dolores Zambrano"},{id:"218483",title:"MSc.",name:"Anna",surname:"Iglesias",slug:"anna-iglesias",fullName:"Anna Iglesias"},{id:"218484",title:"Prof.",name:"Josep",surname:"Brugada",slug:"josep-brugada",fullName:"Josep Brugada"}],corrections:null},{id:"58532",title:"Postmortem Animal Attacks on Human Corpses",doi:"10.5772/intechopen.72929",slug:"postmortem-animal-attacks-on-human-corpses",totalDownloads:2268,totalCrossrefCites:2,totalDimensionsCites:5,hasAltmetrics:1,abstract:"Postmortem animal activity is an important step in incorporating protein, fat, and carbohydrates in corpses to the food chain. Many animal species are members of this food chain. Outdoor corpses may be attacked by many predacious and scavenger animals and exposed to complete destruction, and bones and belongings of the dead person may be scattered all over a large area due to postmortem animal activity. Indoor corpses may be attacked by pets, domestic dogs, cats, ants, and rodents during postmortem period. Besides, if the corpse is in shallow water, other terrestrial predators may harm the corpse. The most important issue in the presence of lesions on the corpse caused by animals is to accurately discriminate between antemortem and postmortem wounds. The extent of the lesions caused by the animals varies according to the sizes of their dentition and jaws, but they share some common characteristics. Lack of bleeding from bitten tissue excepting small amount of extravasated blood, absence of active bleeding, edema, and erythema on the edges of the wound are among these shared characteristics. In this chapter, the subject of postmortem animal attacks on human corpses will be evaluated by revising the recent references.",signatures:"Zerrin Erkol and Erdem Hösükler",downloadPdfUrl:"/chapter/pdf-download/58532",previewPdfUrl:"/chapter/pdf-preview/58532",authors:[{id:"210494",title:"Dr.",name:"Zerrin",surname:"Erkol",slug:"zerrin-erkol",fullName:"Zerrin Erkol"},{id:"237009",title:"Dr.",name:"Erdem",surname:"Hösükler",slug:"erdem-hosukler",fullName:"Erdem Hösükler"}],corrections:null},{id:"57298",title:"Contribution of Forensic Analysis to Shark Profiling Following Fatal Attacks on Humans",doi:"10.5772/intechopen.71043",slug:"contribution-of-forensic-analysis-to-shark-profiling-following-fatal-attacks-on-humans",totalDownloads:1358,totalCrossrefCites:3,totalDimensionsCites:5,hasAltmetrics:0,abstract:"Size assessment and species identification are paramount after a fatal attack for profiling a ‘problem-animal’ that could be specifically eliminated. In addition to ecological and behavioural data about candidate species, forensic analysis can provide critical information for achieving this goal. After providing basic information about fatal attacks and the anatomical features of the three species (white shark, tiger shark and bull shark) that are responsible for >80% of lethal interactions, this chapter presents the most used tools for assessing the species and size of a potential attacker. The size assessment can be done through measurements (on the body of the victim or from good-quality photographs) of the bite width (BW) and bite circumference (BC); the size is then obtained from regressions from the literature between BW/BC and total length. The average interdental distance (IDD) is also used through a similar process. Finally, other details of the wounds, such as the shape of the bite margin or of flesh flaps that directly depend on the jaw characteristics, can also be used to contribute to the final assessment. Although important, a forensic analysis should be complemented by data on shark ecology and behaviour for a more reliable conclusion.",signatures:"Eric Clua and Dennis Reid",downloadPdfUrl:"/chapter/pdf-download/57298",previewPdfUrl:"/chapter/pdf-preview/57298",authors:[{id:"218442",title:"Prof.",name:"Eric",surname:"Clua",slug:"eric-clua",fullName:"Eric Clua"},{id:"220622",title:"MSc.",name:"Dennis",surname:"Reid",slug:"dennis-reid",fullName:"Dennis Reid"}],corrections:null},{id:"57778",title:"Defining Dental Age for Chronological Age Determination",doi:"10.5772/intechopen.71699",slug:"defining-dental-age-for-chronological-age-determination",totalDownloads:2610,totalCrossrefCites:1,totalDimensionsCites:3,hasAltmetrics:0,abstract:"Dental age assessment is one of the most reliable methods of chronological age estimation used for criminal, forensic and anthropologic purposes. Visual, radiographic, chemical and histological techniques can be used for dental age estimation. Visual method is based on the sequence of eruption of the teeth and morphological changes that are caused due to function such as attrition, changes in color that are indicators of aging. Radiographs of the dentition can be used to determine the stage of dental development of the teeth from initial mineralization of a tooth, crown formation to root apex maturation. Histological methods require the preparation of the tissues for detailed microscopic examination. The chemical analysis of dental hard tissues determines alterations in ion levels with age, whereas the histological and chemical methods are invasive methods requiring extraction/sectioning of the tooth. In this chapter, the different techniques and considered studies were overviewed in conjunction with their advantages and disadvantages. It needs to be taken into consideration that rather than restricting on one age estimation technique, using the other available techniques additionally and performing repetitive measurements may be beneficial for accurate age estimation.",signatures:"Fatma Deniz Uzuner, Emine Kaygısız and Nilüfer Darendeliler",downloadPdfUrl:"/chapter/pdf-download/57778",previewPdfUrl:"/chapter/pdf-preview/57778",authors:[{id:"172009",title:"Dr.",name:"Fatma Deniz",surname:"Uzuner",slug:"fatma-deniz-uzuner",fullName:"Fatma Deniz Uzuner"},{id:"200985",title:"Dr.",name:"Emine",surname:"Kaygisiz",slug:"emine-kaygisiz",fullName:"Emine Kaygisiz"},{id:"222232",title:"Prof.",name:"Nilufer",surname:"Darendeliler",slug:"nilufer-darendeliler",fullName:"Nilufer Darendeliler"}],corrections:null},{id:"59040",title:"Forensic DNA Technological Advancements as an Emerging Perspective on Medico-Legal Autopsy: A Mini Review",doi:"10.5772/intechopen.72851",slug:"forensic-dna-technological-advancements-as-an-emerging-perspective-on-medico-legal-autopsy-a-mini-re",totalDownloads:1669,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The importance of biological traces and evidences related to a criminal matter has been recognized for a long time. The examination of the expression of genetic polymorphism has been an integral part of the multidisciplinary field of medico-legal autopsy for over a century. Since the initial application of blood group antigens for personalization of a putative perpetrator in a murder case, the discipline of forensic genetics has evolved as a standard of forensic sciences. The real breakthrough, the application of molecular tools and processes for the in-vitro replication of genetic substances, has increasingly allowed the exploitation of advances of molecular genetics for both forensic and criminal investigations. Although there are certainly many more applications and scientific fields in the medico-legal arena, the relatively fast progress of genetics, which has accelerated recently with state-of-art technologies, can provide ever more relevant information in relation to a corpse or the cause and manner that resulted in the corpse for autopsy. This topic concerns the currently accepted forensic DNA technology, and the last section reviews commonly used markers for nuclear and mitochondrial DNA analysis as well as ongoing research. This review also focuses on the increasingly important non-human sources of DNA, and shortly covers the main aspects of animal forensic DNA examination.",signatures:"Zsolt Pádár, Petra Zenke and Zsolt Kozma",downloadPdfUrl:"/chapter/pdf-download/59040",previewPdfUrl:"/chapter/pdf-preview/59040",authors:[{id:"210728",title:"Ph.D.",name:"Padar",surname:"Zsolt",slug:"padar-zsolt",fullName:"Padar Zsolt"}],corrections:null},{id:"59038",title:"Most Common Medico-Legal Autopsy-Related Human and Nonhuman Biological Samples for DNA Analysis",doi:"10.5772/intechopen.72850",slug:"most-common-medico-legal-autopsy-related-human-and-nonhuman-biological-samples-for-dna-analysis",totalDownloads:1462,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The identification and individualization of biological evidences is crucial to actual criminal investigations. In spite of the differences at the national level, all the legal processes attribute particular importance to forensic DNA analysis. However, none of the qualified results from any professional laboratory can produce substantive, valuable evidence with insufficient quality of samples and/or problems with provision of a pristine and controlled environment. The methodology and efficiency of sampling are distinct in case of living persons and in medico-legal autopsy and crime scenes. This chapter is a short overview from the basic introductory information up to ongoing research, and in accordance with constraints on the chapter size, it briefly discusses the important topics of sample collection at medico-legal autopsy for DNA analysis. The content sorts the major types of samples, reviews the common methods of sampling and the potential risk of poor sampling or contamination transfer. The corpses can be more or less degraded, which in special cases (e.g., paraffin embedded tissues, drowned, burning and/or buried cadaver) allow only for analysis of highly degraded samples. The samples can be associated with tissues of a corpse (e.g., blood, soft tissues, bone, tooth, hair) and/or additional extraneous tissues and remains, which are often mixed (e.g., blood, saliva, semen, vaginal fluid, debris of fingernails) on the corpse.",signatures:"Zsolt Pádár, Petra Zenke and Zsolt Kozma",downloadPdfUrl:"/chapter/pdf-download/59038",previewPdfUrl:"/chapter/pdf-preview/59038",authors:[{id:"210728",title:"Ph.D.",name:"Padar",surname:"Zsolt",slug:"padar-zsolt",fullName:"Padar Zsolt"},{id:"211335",title:"Dr.",name:"Petra",surname:"Zenke",slug:"petra-zenke",fullName:"Petra Zenke"},{id:"211337",title:"Dr.",name:"Zsolt",surname:"Kozma",slug:"zsolt-kozma",fullName:"Zsolt Kozma"}],corrections:null},{id:"57175",title:"Application of CO-oximeter for Forensic Samples",doi:"10.5772/intechopen.71182",slug:"application-of-co-oximeter-for-forensic-samples",totalDownloads:1432,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"CO-oximeter is routinely used in clinical practice, and it has been applied in the field of forensic medicine. It is a simultaneous and nondestructive technique for the analysis of total hemoglobin (Hb) and various Hb species, such as oxyhemoglobin, reduced hemoglobin, carboxyhemoglobin, and methemoglobin. It automatically measures the proportion of each species of Hb and oxygen contents. This is an easy, rapid, and convenient way as the laboratory test. Since there are many advantages such as no necessity of sample preparation, easy handling, and portability, it may provide valuable information for forensic diagnosis. In the present paper, we discuss about the diagnostic application of CO-oximeter in the field of forensic medicine.",signatures:"Hiroshi Kinoshita, Naoko Tanaka, Ayaka Takakura, Mostofa Jamal,\nAsuka Ito, Mitsuru Kumihashi, Shoji Kimura, Kunihiko Tsutsui, Shuji\nMatsubara and Kiyoshi Ameno",downloadPdfUrl:"/chapter/pdf-download/57175",previewPdfUrl:"/chapter/pdf-preview/57175",authors:[{id:"200704",title:"Dr.",name:"Hiroshi",surname:"Kinoshita",slug:"hiroshi-kinoshita",fullName:"Hiroshi Kinoshita"},{id:"200706",title:"Dr.",name:"Naoko",surname:"Tanaka",slug:"naoko-tanaka",fullName:"Naoko Tanaka"},{id:"210709",title:"BSc.",name:"Ayaka",surname:"Takakura",slug:"ayaka-takakura",fullName:"Ayaka Takakura"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"7046",title:"Wound Healing",subtitle:"Current Perspectives",isOpenForSubmission:!1,hash:"fa7b870ad29ce1dfcf6faeafdc060309",slug:"wound-healing-current-perspectives",bookSignature:"Kamil Hakan Dogan",coverURL:"https://cdn.intechopen.com/books/images_new/7046.jpg",editedByType:"Edited by",editors:[{id:"30612",title:"Prof.",name:"Kamil Hakan",surname:"Dogan",slug:"kamil-hakan-dogan",fullName:"Kamil Hakan Dogan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8227",title:"Disorders of Consciousness",subtitle:"A Review of Important Issues",isOpenForSubmission:!1,hash:"1ead1706130f8a55f19ec5cc81ef245d",slug:"disorders-of-consciousness-a-review-of-important-issues",bookSignature:"Kamil Hakan Dogan",coverURL:"https://cdn.intechopen.com/books/images_new/8227.jpg",editedByType:"Edited by",editors:[{id:"30612",title:"Prof.",name:"Kamil Hakan",surname:"Dogan",slug:"kamil-hakan-dogan",fullName:"Kamil Hakan Dogan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"243",title:"Forensic Medicine",subtitle:"From Old Problems to New Challenges",isOpenForSubmission:!1,hash:"132b119de3a751f6c764b7cc15b85a14",slug:"forensic-medicine-from-old-problems-to-new-challenges",bookSignature:"Duarte Nuno Vieira",coverURL:"https://cdn.intechopen.com/books/images_new/243.jpg",editedByType:"Edited by",editors:[{id:"31385",title:"Dr.",name:"Duarte Nuno",surname:"Vieira",slug:"duarte-nuno-vieira",fullName:"Duarte Nuno Vieira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10579",title:"Forensic Analysis",subtitle:"Scientific and Medical Techniques and Evidence under the Microscope",isOpenForSubmission:!1,hash:"54012b7d1952b634ff1bf86b8ce4a771",slug:"forensic-analysis-scientific-and-medical-techniques-and-evidence-under-the-microscope",bookSignature:"Ian Freckelton",coverURL:"https://cdn.intechopen.com/books/images_new/10579.jpg",editedByType:"Edited by",editors:[{id:"29183",title:"Prof.",name:"Ian",surname:"Freckelton",slug:"ian-freckelton",fullName:"Ian Freckelton"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. 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Critical infrastructures consist of physical and cyber assets, systems, and networks, that are essential for the functioning of a society and economy. The damage to a critical infrastructure, caused by natural (e.g., earthquakes, fire) or anthropic (e.g., hacking, sabotage, vandalism) events may produce a significant negative impact for other systems and thus amplify the effects and reducing the system capability to return to an equilibrium state.
In a scenario consisting of multiple infrastructures with several dependencies among them, the implementation of mitigation controls that may affect the resilience level of the systems, is valuable to preserve and restore the essential societal services. Since resilience-related controls will positively affect the capability of a system to resist, absorb, adapt and/or recover from the effects of a hazard in a timely and efficient manner, it is important to analyse the effect of such controls, in order to support decision making related to the selection and prioritization of alternative mitigation controls. For example, when electric transmission or distribution networks are affected by disturbances such as floods, in general, mitigation and restoration actions are performed through protection and automation devices and manual interventions to reduce the duration of the outage and preserve the power supply to critical systems such as hospitals [1, 2, 3].
In the US, in order to support the different players involved in modeling, simulation, and analysis of the nation’s critical infrastructures, the National Infrastructure Simulation and Analysis Center (NISAC) was established. NISAC analysts assess critical infrastructure risk, vulnerability, interdependencies, and event consequences. In Europe, in order to support the different players involved in the resilience enhancement, emergency and response management of critical infrastructures to natural and man-made hazards, the Infrastructure Simulation and Analysis Centre (EISAC) is aiming at establishing a collaborative, European-wide network of national centres empowered by core technologies.
This paper extends a recent work on critical infrastructure dependency analysis and introduces time-based analysis models to study the evolution of restoration actions in a scenario of dependent systems. This model was integrated into CIPCast Decision Support System, named CIPCast hereafter, that is part of the on-going products and activities developed in the context of the Italian node of EISAC, called I-EISAC, aiming to support infrastructure and civil protection operators operators in the risk assessment of critical infrastructures.
CIPCast can provide an operational (24/7) forecast and risk analysis for different infrastructures in a specific area showing risk maps of infrastructure elements which could be damaged by different events e.g. earthquakes. In particular, CIPCast allows: (i) Assessing the seismic vulnerability of different EDNs components; (ii) estimating possible earthquake-induced physical damage; (iii) estimating the impact on service(s) functionality in terms of outage duration associated with the predicted physical damage and considering the known inter-dependencies; (iv) estimating the consequences of the predicted outages, according to several metrics accounting for economic losses and reduction of citizens well-being.
The remainder of the paper is organized as follows. Section 2 presents related works in the area. In Section 3, we introduce notions of time-based and resilience-aware dependency analysis. In Section 4, we apply the analysis to a case study related to the area of Rome. Finally, in Section 5, some conclusions and ideas for future works are drawn.
Modeling critical infrastructures and urban systems for risk assessment purposes is a well-known and established research field. Preliminary work that laid the foundation in this area is often attributed to Rinaldi et al., first in [4] where authors categorised dependencies in critical infrastructures as Physical, Cyber/informational, Geographic, Logical and Social dependencies, and later in where authors created taxonomies for disruptions or outages and marked them as cascading, escalating, or common-cause [5]). Critical infrastructure modeling events where first defined as cascade initiating (i.e., an event that causes an event in another CI) and cascade resulting (i.e., an event that results from an event in another CI) by the empirical study of Van Eeten et al. [6].
Basic modeling approaches usually fall within one of the following six categories categories [5, 7]:
Aggregate supply and demand tools, which evaluate the total demand for infrastructure services in a region and the ability to supply those services
Dynamic simulations, which analyze the effects of disruptions, and their associated consequences.
Agent-based models, which model operational attributes and states of infrastructure operation; usually on a graph model.
Physics-based models, which utilize standard engineering techniques such as power flow and stability analyses for electric power grids.
Population mobility models that focus on geospatial movement.
Leontief input–output models, which utilize linear, time-independent analysis of commodities among infrastructure sectors.
Our approach can be classified as both dynamic simulation and agent-based model. It utilizes operational attributes to model interdependencies in urban environments as a graph, while still allowing for dynamic input of data in order to analyze the effects of disruptions in the urban web along with quantifying their associated consequences.
Each critical infrastructures sector has its own group of research publications that utilize some of the aforementioned techniques to model and analyse risk. For example, in the water sector, OpenMI [8] supports federated modeling and simulation for water systems, while multiple publications exist that analyze interdependencies at the transportation sector using traffic flow simulation models [9], Bayesian networks to model the correlation structure of highway networks [10] etc. The Energy sector is also a highly researched area. Wide Area Measurement Systems (WAMS) have been extensively researched, especially for the detection of optimal locations for metering device placement, in order to achieve increased robustness of the WAMS infrastructure. Modeling and quantifying dependencies between the electrical and information infrastructures of WAMS in smart grids has been recently studied in [11]. Topological observability of power systems has been fully described in [12]. Still, cross-sector approaches do exist that opt to combine combine models from multiple sectors and enable integrated or federated simulations. Some examples include DIESIS [13] and EPIC [14].
The North American Electric Reliability Corporation (NERC) has recently developed Critical Infrastructure Protection (CIP) standards which introduce cyber security compliance requirements for power systems [15]. Various research has developed methodologies that aim to quantify these requirements. In [15], authors proposed a risk-based dependency analysis for modeling and quantifying dependencies over time, which was also later used in [11] along with electrical centrality metrics to quantify the level of each dependencies in the smart grid. A different approach for simulating common-cause and cascading effects was also introduced by the authors in [16]. Similarly, authors in [17] proposed to use access graph models to analyze trust between systems and the security exposure of a large scale smart grid environments. In [18], authors developed a graph-based workflow model for assessing the security risks from cybersecurity incidents on electric grids and build relevant scenarios.
The presented approach is mostly based on the methodologies presented in [15]. We aggregate data into dependency matrices and utilize models from real-world urban systems to map them into dependency graphs. The presented approach is based on network modeling and path analysis. It depicts dependencies of the connected urban infrastructures as a graph and identifies high risk, critical paths that are either modeled as flows of information, power or other related type of dependency. Similar techniques have been used in uniform [19, 20] or flow models [12, 21].
We consider a directed graph
Our model extends the cumulative dependency risk model of [23, 24]. Without loss of generality, let
Based on the definitions of [23], the risk exhibited by a node due to its
Then the
Let
By combining Resilience and Threat variables with the directed graph model of interdependent POIs, we can perform a granular analysis of the risk imposed by POI interdependencies based on their risk and resilience levels. We opt to use the multi-risk dependency analysis method as proposed in [23, 24, 25] and implemented later in [15].
A many-to-many mapping may exist between the threats and the security controls, i.e. a security control may mitigate, at some extent, one or more threats, while a security threat may require one or security controls. For each security control, different weights can be used to define the effectiveness of a control against different threats and also for their application to specific infrastructures. This is a realistic modeling of resilience, since many controls do not have the same effect against all threats and different infrastructures are benefited more than others from specific security controls, given the nature of the infrastructure and the intrinsic characteristics of each threat.
For example, if infrastructure (node)
In the aforementioned example, node
Generalising this to
where
For example, if we consider an electric substation, in order to increase its resilience against a seismic threat, there might be several options aiming to reduce the likelihood of the threat that produces a failure and/or to reduce the magnitude of the impact e.g. to enhance the structural properties of the building or increment the number of technical crews so that in case of a failure the duration of outage can be reduced.
In a complex study of a large CI system, such as the city of Rome, the interplay among network topology, size, quality and distribution of technical systems along the network, emergency management ability do have an impact on the evolution and the duration of a crises and thus influence the system resilience. They have been thus studied in order to establish the “sensitivity” of the resilience score with respect to each one of the described properties [3].
Conveniently, the Resilience introduced by a security control against a specific threat on the entire network of interdependent nodes can be algorithmically modeled as a matrix multiplication. For the first matrix, columns represent existing nodes, while rows represent different security controls. Cell values depict the possibility of a security control to mitigate some part of the impact of a specific threat for each node present in the graph. The second matrix depicts the impact reduction that can be achieved by security controls onto the existing interdependent nodes. Similarly, columns represent existing nodes, while rows represent different security controls, but, here cell values depict the maximum potential impact reduction achieved at each node by the implementation of each security control. Thus, in this matrix, cells have negative values. Resilience is then modeled as the matrix multiplication of the two matrices (threat reduction and impact reduction matrices), as depicted in Figure 1.
Resilience security control calculation for the entire network against a single
By combining Eq. 1 and Eq. 2 with Eq. 3, the cumulative dependency risk in the presence of resilience controls can be defined as follows:
As discussed above,
Impact
Growth rates
which begins at a slow pace and gradually increases in speed. “Linear” growth rates follow a typical approach
whereas “fast” impact growth rates are calculated using a logarithmic approach
in which incidents impose a very fast impact growth rate that gradually decreases in speed. For any
In real-world implementations of the methodology, all aforementioned values for
The above equations need some sort of value ranges in order to quantify results. To support calculation of these equations, we opted to use the same scales as in [15]. All the values are assigned from the following Likert scales:
Each Impact value reflects a different qualitative criterion, based on the needs and threats of any given infrastructure. Nevertheless, quantification is uniform amongst all possible implementations, where a value of 1 reflects minimum to no Impact, while a value of 9 reflects catastrophic impact of an incident.
The city center of Rome was chosen as a case study due to the high concentration of various commercial activities and power centres both local and international as well as the presence of CIs which are essential to maintain vital societal functions (Figures 2 and 3). In particular, the area of interest holds the major Italian government offices,
The area of interest: an urban district of Rome. The map was anonymized and MV Electric substations and Base Transceiver Stations were removed to hide sensitive information.
The dependency graph used in the case study.
As reported in Table 1, we considered
the Electric Distribution Network (EDN) of Rome consisting of
the Mobile Telecommunication System consisting of
the Water Supply Network (WSN) consisting of
the Railway system including
a set of hospitals, medical offices and pharmacies;
a set of government offices and embassies;
a set of cash dispensers;
a set of restaurants.
Category | Subcategory | Acronym | Nr. |
---|---|---|---|
Energy | MV Electric substation | ES | 40 |
Telecommunications | Base Transceiver Station | BTS | 31 |
Finance | Cash Dispenser | CD | 20 |
Government | Government Office | GO | 15 |
Embassy | EM | 20 | |
Transport | Railway Station | RS | 12 |
Health | Medical Office | DO | 15 |
Pharmacy | PH | 12 | |
Hospital | HP | 5 | |
Food | Restaurant | RE | 10 |
Water | Water Pumping station | WP | 1 |
182 |
CI categories and components modeled in the case study.
In order to model the interdependencies among the different nodes, we assumed a cyber risk assessment as the case scenario. In particular, we considered a
The dependency matrix is consistent with the main cyber interdependencies that exist among the nodes modelled in the scenario although only a limited number of CI were considered for each sector present in the dependency matrix. Indeed, the electric substations (ES) supply energy to all nodes of other CI and thus a failure occurring in an ES would be disruptive for all nodes that receive energy from that ES. In addition, some of the ES are Remotely controlled and thus a failure occurring in those BTS nodes that in turn provide telecommunication services to the Remotely Controlled ES may compromise the control operations of the EDN.
In the absence of information regarding specific interdependencies, we employed a proximity criterion to model the relations among specific nodes. For example, we assumed that each energy consumer (i.e., all nodes that are not ES) is supplied by the nearest ES as well as each internet/telephony consumer is supplied by the nearest BTS. In addition, we did not model the intra-sector dependencies i.e. any dependency among the nodes of the same CI sector was not considered.
As described previously, we employed the dependency matrix defined in [26] to model the interdependencies of the case study. That matrix was filled by gathering over
Inbound Dependencies | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
CI Sector | ES | BTS | CD | GO | EM | RS | DO | PH | HP | RE | WP |
— | 0.36 | — | 0.34 | 0.34 | 0.43 | 0.39 | 0.39 | 0.39 | — | 0.31 | |
0.7 | — | 0.45 | 0.4 | 0.4 | 0.44 | 0.51 | 0.51 | 0.51 | — | 0.34 | |
0.71 | 0.72 | — | 0.4 | 0.4 | 0.4 | 0.42 | 0.42 | 0.42 | 0.44 | 0.5 | |
0.59 | 0.51 | 0.7 | — | — | 0.36 | 0.61 | 0.61 | 0.61 | 0.36 | 0.51 | |
0.59 | 0.51 | 0.7 | — | — | 0.36 | 0.61 | 0.61 | 0.61 | 0.36 | 0.51 | |
0.68 | 0.4 | 0.42 | 0.29 | 0.29 | — | 0.5 | 0.5 | 0.5 | 0.51 | 0.3 | |
0.41 | — | 0.3 | 0.51 | 0.51 | — | — | — | — | — | 0.44 | |
0.41 | — | 0.3 | 0.51 | 0.51 | — | — | — | — | — | 0.44 | |
0.41 | — | 0.3 | 0.51 | 0.51 | — | — | — | — | — | 0.44 | |
— | — | — | 0.27 | 0.27 | — | 0.38 | 0.38 | 0.38 | — | — | |
0.49 | — | — | 0.29 | 0.29 | 0.32 | 0.36 | 0.36 | 0.36 | — | — |
The likelihood matrix used in the case study.
The columns for each sector represent how that sector is dependent by data coming into that sector. Most organisations can intuitively estimate this value, and that’s how the data was collected in [26]. For example, in Table 2, column
Based on this matrix, we normalised the values and neglected the intradependencies and the low intradependencies. In other words, we treated the cyber vulnerability of a node as a likelihood that the node being affected. The resulting matrix is shown in Table 2.
Given the absence of information regarding the security controls implemented by the considered nodes, we assumed that each node
ES, BTS, CD, GO, EM | 0.3 |
RS, HP, WP | 0.1 |
DO, PH, RE | 0 |
Resilience influence of security control
In order to assess the impact of cyber attacks on the nodes, we considered the work of Fekete [27] that defines three impact assessment criteria in terms of critical proportion, time and quality aspects. Critical proportion refers to the number of elements or nodes of a CI such as critical number of services, size of population or number of customers affected and redundancies. Critical time considers aspects such as duration of outage, Mean Time to Repair (MTTR), Mean Time to Functionality (MTTF) and business continuity or interruption. Critical quality refers to the quality of the services delivered (e.g., the water quality) or the public trust in quality (e.g., trust in finance, feeling of security).
In the following subsections, a description of how the mentioned impact assessment criteria were applied to the case study will be provided. In particular, the assumptions that were made to take into account such criteria will be described in order to model the expected time-related impact
In order to apply the critical proportion criterion, given the difficulty of obtaining the number of customers supplied by a specific node from the CI owners, we assumed the number of inhabitants living in the geographical area where the specific node is located as the number of customers. Indeed, the areas considered are the census areas delivered by the
Furthermore, the critical quality criterion was applied to compute
Table 4 summarises the criteria applied based on the sector nodes considered. It should be noticed that while
Case | Impact assessment criterion | ||
---|---|---|---|
A | ES, BTS, RS, CD | Nr. of customers | node-dependent |
B | GO, EM, DO, PH, HP, RE | Service criticality | sector-dependent |
Maximum expected impact criteria for the dependency risk subchain
Inbound dependencies | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
CI Sector | ES | BTS | CD | GO | EM | RS | DO | PH | HP | RE | WP |
— | — | 7 | 4 | 4 | 4 | 7 | — | 7 | |||
— | 7 | 4 | 3 | 3 | 6 | — | 6 | ||||
— | 3 | 2 | 2 | 2 | 2 | 4 | 2 | 2 | |||
8 | 8 | 3 | — | — | 3 | 3 | 5 | 3 | 5 | ||
4 | 4 | 2 | — | — | 3 | 2 | 2 | 4 | 2 | 4 | |
2 | 3 | — | 3 | 3 | 4 | 3 | 3 | ||||
2 | — | 2 | 3 | 2 | — | — | — | — | — | 3 | |
2 | — | 2 | 3 | 2 | — | — | — | — | — | 3 | |
7 | — | 4 | 5 | 4 | — | — | — | — | — | 5 | |
— | — | — | 3 | 2 | — | 2 | 2 | 2 | — | — | |
3 | — | — | 3 | 3 | 3 | 3 | 3 | 3 | — | — |
Maximum expected impact matrix used in the case study.
Let
Table 6 shows the percentage of reduction
ES, BTS | any | 0.5 |
CD, GO, EM, RS, DO, PH, HP, RE, WP | any | 1 |
Percentage of reduction
Regarding the critical time criterion, we considered the expected duration of failure of nodes to compute the impact and growth time matrices. In particular, we assigned a low value to sectors that are highly dependent on the data availability and that produce a quick impact such as Energy and Telecommunication and Finance and assigning a higher value to other sectors such as Water and Food that produce their negative effect in a longer period. The resulting impact time matrix is shown on Table 7.
Inbound dependencies | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
CI Sector | ES | BTS | CD | GO | EM | RS | DO | PH | HP | RE | WP |
— | 3 h | — | 3 h | 3 h | 3 h | 3 h | 3 h | 3 h | — | 24 h | |
3 h | — | 1 h | 3 h | 3 h | 3 h | 3 h | 3 h | 3 h | — | 3 h | |
3 h | 3 h | — | 3 h | 3 h | 3 h | 12 h | 12 h | 3 h | 2w | 24 h | |
3 h | 3 h | 3 h | — | — | 12 h | 12 h | 12 h | 12 h | 2w | 24 h | |
3 h | 3 h | 3 h | — | — | 12 h | 12 h | 12 h | 12 h | 2w | 24 h | |
3 h | 3 h | 3 h | 12 h | 12 h | — | 12 h | 12 h | 12 h | 2w | 24 h | |
3 h | — | 3 h | 24 h | 24 h | — | — | — | — | — | 24 h | |
3 h | — | 3 h | 24 h | 24 h | — | — | — | — | — | 24 h | |
3 h | — | 3 h | 24 h | 24 h | — | — | — | — | — | 24 h | |
— | — | — | 2w | 2w | — | 2w | 2w | 2w | — | — | |
24 h | — | — | 24 h | 24 h | 24 h | 24 h | 24 h | 24 h | — | — |
The maximum impact time matrix used in the case study.
Regarding the recovery time matrix, we modeled a time
Inbound dependencies | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
CI Sector | ES | BTS | CD | GO | EM | RS | DO | PH | HP | RE | WP |
— | 15 m | — | 15 m | 15 m | 15 m | 15 m | 15 m | 15 m | — | 15 m | |
3 h | — | 1 h | 1 h | 1 h | 1 h | 1 h | 1 h | 1 h | — | 1 h | |
3 h | 3 h | — | 3 h | 3 h | 3 h | 12 h | 12 h | 3 h | 2w | 24 h | |
3 h | 3 h | 3 h | — | — | 12 h | 12 h | 12 h | 12 h | 2w | 24 h | |
3 h | 3 h | 3 h | — | — | 12 h | 12 h | 12 h | 12 h | 2w | 24 h | |
3 h | 3 h | 3 h | 12 h | 12 h | — | 12 h | 12 h | 12 h | 2w | 24 h | |
3 h | — | 3 h | 24 h | 24 h | — | — | — | — | — | 24 h | |
3 h | — | 3 h | 24 h | 24 h | — | — | — | — | — | 24 h | |
3 h | — | 3 h | 24 h | 24 h | — | — | — | — | — | 24 h | |
— | — | — | 2w | 2w | — | 2w | 2w | 2w | — | — | |
24 h | — | — | 24 h | 24 h | 24 h | 24 h | 24 h | 24 h | — | — |
The maximum recovery time matrix used in the case study.
Regarding the impact growth rate, Table 9 shows the the criterion adopted and Table 10 shows the resulting values for each couple of nodes. We considered the same growth rate for the recovery actions.
Growth rate node | ||||
---|---|---|---|---|
Slow | Linear | Fast | ||
Growth rate node | Slow | Slow | Linear | |
Slow | Linear | Fast | ||
Linear | Fast | Fast |
Impact growth rate metric.
Inbound dependencies | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
CI Sector | ES | BTS | CD | GO | EM | RS | DO | PH | HP | RE | WP |
— | F | — | F | F | F | F | F | F | — | L | |
F | — | L | L | L | L | L | L | L | — | S | |
F | L | — | L | L | L | L | L | L | L | S | |
F | L | L | — | — | L | L | L | L | L | S | |
F | L | L | — | — | L | L | L | L | L | S | |
F | L | L | L | L | — | L | L | L | L | S | |
F | — | L | L | L | — | — | — | — | — | S | |
F | — | L | L | L | — | — | — | — | — | S | |
F | — | L | L | L | — | — | — | — | — | S | |
— | — | — | S | S | — | S | S | S | — | — | |
L | — | — | S | S | S | S | S | S | — | — |
The impact growth rate matrix used in the case study.
The execution of the model based on the graph of 182 nodes produced about 750.000 risk paths with order ranging from five to eight and potential risk values between 0.27 and 9.53. Figure 4 shows some significant dependency paths together with their cumulative dependency risk values.
A set of dependency risk paths with cumulative dependency risk. Dashed/continuous lines indicate the risk without/with the implementation of security controls.
The charts show that one dependency path (
Figure 5 shows a map representation of the dependency risk paths considered in Figure 4 with the census areas involved. In particular, let
Result map showing the risk value of each census area.
Results depicted in Figure 4 indicate cascading events between infrastructures. Each one of the four scenarios was validated to be true against real world data and historical analysis of such infrastructures. Following this, results indicate that the presented methodology is able to both (i) effectively project adverse effects from cascading events and accurately predict potential impact over time periods, and also (ii) highlight direct and indirect dependency vulnerabilities between highly dependent CIs.
On the latter, results delineate the criticality behind dependencies of Telecommunications and the Electrical sector. The sharp increase in impact over a very short time period (purple line, scenario 1) clearly shows that potential unavailability of the Electrical sector quickly and critically affects the Telecommunications. We followed up on this finding and results are proven true both from empirical analysis and also from historical data on locations analyzed by the tool.
Another potential use of the presented methodology includes capturing the effect of applying security controls and how these controls affect the resilience of systems over time. By analyzing the impact escalation and trajectory in analyzed attack paths, we see that the level of risk reduction for each of the presented scenarios is directly related with the time of deployment. Early application of security controls (scenario CD1, ES1, BTS1, GO1, ES2) seems to reduce the overall risk by 25% in less than two hours after the initiation of the attack path, while controls implemented later during the exposure to the adverse event show relatively smaller mitigation percentages of the overall risk (around 18%).
Red areas shown in Figure 5 are highly populated areas containing electric nodes thus producing possible high impact in case of failure. This explains why several nodes of the subchains with high cumulative dependency risk are concentrated in this area.
By extending previous time-based dependency analysis models and by integrating the effect of resilience-related security controls, in this paper we have examined the effect of possible mitigation strategies in dynamically reducing the consequences of cascading effects. The model was applied to a real case study involving an urban area of Rome where a number of critical infrastructures deliver services to inhabitants and businesses. The model was set up by considering a precomputed dependency graph that exhibits the cyber dependencies of a set of infrastructures. The results highlight the most critical dependency chains and the areas with high concentration of critical nodes. The model was integrated into CIPCast Decision Support System allowing all actors involved in securing critical infrastructures to plan mitigation strategies aiming at reducing the overall risk of service degradation in the considered area.
Authors wish to acknowledge the funding of project RAFAEL (MIUR ARS01_00305) which has partly funded the research activities carried out for this work.
Loss of vitality decreases the physical properties, translucency, and fracture resistance of the remaining tooth structure. A load applied on upper teeth makes them move towards labially i.e. up and outwards having no support from adjacent teeth treated endodontically will have no central core of dentine and so the stresses are mainly absorbed by margins. Unless there is bulk in this region simple restoration of the coronal form may be insufficient to reinforce the tooth. So to reinforce the crown, a post is placed in the root canal. By this, the potential point of fracture from the gingival margin can be shifted towards the root apex. Similarly loads on lower teeth cause down and inward movement which closes the arch and also gains support from adjacent teeth. So here reinforcement with the post is not as important compared to upper teeth. But still, as preparation of access cavity may leave little of dentine placement of post may be desirable. Endodontically treated teeth often require partial or complete coverage restorations according to the amount of remaining tooth structure. Endodontic treatment is usually the consequence of caries followed by pulpal infection or traumatic damage to a tooth. Therefore, these teeth also suffer from loss of structural integrity, necessitating restoration of the tooth for esthetic and functional rehabilitation. It was believed that the insertion of a post into an endodontically treated tooth reinforced and increased fracture resistance [1].
It is that part of the prosthesis usually made of metal that is fitted into a prepared canal of a natural tooth
Depending upon the design of the post the basic designs available are
round ended
tapered ended
parallel ended
Depending on surface texture it is divided into.
smooth sided
serrated
threaded posts.
Examples of some posts are
flexi posts, endoposts, plastic impression posts, brasslers ER casting post, weissmans dentatus post, para post, v- lock active post etc.
Parallel sided posts advantages
Better retention, better distribution of forces.
Disadvantages are.
Fits only at the apical part of the canal,requires more dentine to be removed.
Tapered posts advantages are.
Better conforms to the canal, less removal of dentine.
Disadvantages are.
Less retentive than other posts, causes greater stress concentration and causes wedging affect.
Here retention can be increased by controlled grooving.
Of all the posts threaded posts are more retentive but these are well known to cause root fracture due to increase in forces at each coil of the threaded during insertion of the post.
Schematic illustration of an endodontically-treated tooth restored by the post-core system.
According to Caputo and Standlee the self-threaded pins and friction lock pins should not be used in endodontically treated teeth [2].
According to Johnson and Sakamura, parallel sided posts resists tensile forces 4.5 times greater than tapered posts [3].
What is parapost?
parallel pins that are added to the prefabricated post, which provides resistance to rotation and some minimal additional retention.
According to colley parallel sided serrated posts of 5.5 mm long is more retentive than tapered post of 8 mm long [4].
The ideal required length of the post is 2/3 the length of the root or the length of the clinical crown, whichever is longer and the diameter of the post is 1/3 of the diameter of the root [it is the maximum]
Reinforced with black carbon fibers which are later coated with quartz fibers to mask the black color and to improve the easthetics. These posts possesses inherent flexibility that is similar to that of natural teeth [dentine], allowing the post to behave similar to the radicular dentine, which absorbs stresses and prevents root fracture. at the same time these posts causes failure of the cement seal at the margins of the artificial crown, especially when the ferrule is minimum [5].
These contain zirconium oxide, a medicine for orthopedic implants. These should be used along with composite cores. These have less tensile strength and may fracture when subjected to shear stresses [5].
These include cold—glass. Plasma treated poly ethylene woven fibers embedded in conventional resin composites. These are weaker than cast metal posts and cores. These have inferior strength combined with undesirable flexibility [5].
It is the centre or base of the structure.
core materials used for anterior teeth are:
Plastic materials like amalgam or glass ionomer cement or composites.
Resin or wax.
core materials used for posterior teeth are.
Cast gold core.
Resin core or composite core with metal post.
Resin or composite core with a cast pins.
In vitro studies states that, when load is applied on a tooth, root fracture is less in teeth restored with resin core, compared with amalgam and cast gold cores [6].
Trauma and decay are often associated with an extensive loss of tooth structure, requiring a restoration for esthetic and functional rehabilitation of the tooth. Often caries leads to loss of tooth structure and vitality of the pulp. Endodontic treatment is necessary in such cases. Adequate anchorage for restoration cannot be achieved if a significant amount of coronal section of the tooth is lost i.e. when only one wall or no wall is remaining. To increase the retention of the restoration post and core treatment is required.
Endodontic treatment influences the strain values and fracture resistance of the remaining tooth [7]. Most of the endodontic treatment failures are influenced by masticatory load. In general, failure rates tend to increase concomitantly as occlusal load increases. Failure loads have been shown to increase as parallelism approaches the load angle between the long axes of the teeth i.e. under lateral loading, failure tends to occur more readily [8]. Teeth which are nearer to transverse horizontal axis are subjected to increased amount of load as compared to anterior teeth. The fracture resistance of the tooth is also directly proportional to remaining bulk of dentin. Post space preparation can increase the amount of dentin removed thus affecting the load bearing capacity of the tooth. To prevent the major tragedy of vertical root fracture (VRF) cases, researchers have been focusing on materials used for post fabrication, designs of the post, luting agents, and the ferrule effect.
Various types of post and core systems have been introduced in dentistry. Endodontic post and core may be cast using material such as gold and nickel-chromium (Ni-Cr), or they may be prefabricated, such as titanium, stainless steel posts and fiber posts. For many years, the custom made posts have been the choice of restoration for endodontically treated teeth. However custom-made posts are technique-sensitive. The elution of the metal ions from these posts can cause metal allergy [9]. Another disadvantage of cast post being higher modulus of elasticity than dentin, which increases the risk of catastrophic failure [10]. Due to these disadvantages, these posts are progressively being replaced by titanium post. Use of a straight titanium posts requires excessive post space preparation in the curved canals [11]. This disadvantage of straight titanium post can be overcome by bendable titanium posts due to its flexible nature. Bendable titanium post can be used for various purposes, for instance, it can be included in preparation of the core when the axis of the crown of the tooth being restored has to be altered to place two or more posts, if necessary, or they can be placed in curved root canals since they can be contoured to follow the canal anatomy, thus bending internally, creating a mechanical lock for the resin core and increasing the retention surface.
Evidence remains controversial regarding the most efficient form of post for restoring endodontically treated teeth. The reduced load bearing capacity of the endodontically treated teeth being the one of the major concerns; fracture resistance provided by different posts needs to be compared.
One of the most frequent procedures of restorative dentistry is the restoration of mutilated and endodontically treated teeth. It is also difficult to repair these teeth since significant quantities of the coronal tooth structure is lost as a result of decay, prior restorative treatment, endodontic access and fractures. Restoration of an endodontically treated tooth needs a good understanding of its physical as well as biomechanical properties, along with sound knowledge of its anatomy as well as endodontic, periodontal, restorative and occlusal principles. Even though the availability of various restorative materials for endodontically treated teeth has increased over few years, the principle of restoring it remains the same [68]. When a significant coronal section has been lost, resulting in the presence of one wall or no wall remaining, then adequate anchorage for the restoration cannot be achieved [69].
With the aid of a post, anchorage can be gained in such conditions. A post is described as the restoration segment inserted into the root canal to help maintain a core component. It can be made of metal or non-metallic compounds. The main objective of the post is to provide retention for the core and the coronal restoration [29, 70]. Sorensen in 1984 stated that the reason for placing a post in the root canal is to retain a crown and not to reinforce the tooth. Posts should not be positioned arbitrarily because post space preparation introduces a degree of risk to a restorative operation by disrupting the seal of the root canal filling, which can lead to micro-leakage. The risk of perforation increases due to the removal of sound tooth structure. Tooth fracture can also occur because of weakening of roots due to removal of sound tooth structure.
It is preferred that physical properties of the tooth i.e. the dentin should match with the physical properties of post system. An ideal post should distribute the functional stresses along the root surface in such a manner that minimum stresses are developed. Esthetics of the post should be compatible with the surrounding tissue. An ideal post should have easy retrievability, good retention and should be compatible with core material. They should also be available at a reasonable cost and should be easy to use. The indications for a post have been modified over the years based on the advantages of the adhesive restoration principles, which may obviate the need for the posts [71]. The remaining amount of tooth structure determines the stability for the restoration. In addition, the tooth’s prognosis is influenced by different factors such as occlusal contacts, its location in dental arch and ferrules [71].
1.5 to 2 mm height of ferrule is the minimum requirement to obtain sufficient fracture resistance. 20 The ferrule with the help of core and dentin reduces the stress on the entire restoration. However, researchers have indicated that it is possible to overcome the lack of fracture protection that may occur in the absence of ferrules using adhesive agents [70, 71].
A further benefit of flexible posts is that dentine elimination is reduced by following the morphology of the channels in curved channels, while direct positioning in the post increases dentine elimination as the length (surface area) increases. Another explanation for this is that the curvature region starts after the 7 mm mark. This is where the thickness of the dentine decreases and there is a very high chance of strip perforation [72].
Its not always necessary to have a complete coverage except when a plastic restoration has limited prognosis. Teeth which are badly destructed due to caries,which can be used for RPD or FPD.
Posterior teeth are subjected to greater stresses because of their position i.e. closer to the insertion of the muscles of mastication. This combined with their morphologic characteristics makes them more susceptible to fracture.
Complete coverage is recommended on teeth with a high risk of fracture especially maxillary premolars as they have long, thin and curved roots which gives best protection against fracture but at the same time considerable tooth reduction must be done and in these cases a post and core foundation is needed for better retention of the prosthesis.
Its commonly believed that endodontically treated teeth are weak than normal teeth which may be due to low moisture content.[not proved experimentally]. so attempts have been made to increase strength by adding posts.
Studies reveal that no significant reinforcement results with the post, because teeth when loaded, stresses are more at the facial and lingual aspects of the root and post being at centre is minimally stressed and does not help prevent fracture. However some contradicts this assumption.
Disadvantages of placement of the post:
It requires an additional operative procedure. Additional tooth structure must be removed. if post fails it is difficult to restore the tooth later for a complete crown. Post can prevent future endodontic treatment.
when a complete coverage is not necessary, post is contraindicated in that tooth.when there is extensive loss of tooth structure which can be used for a FPD or RPD a complete coverage is mandatory.
All most all the principles of normal tooth preparation applies to the endodontically treated teeth. Ideally coronal half of the post hole will have been left open at the time of obturation. if not care must be taken not to deviate from the canal while opening. Guidance can be achieved by softening the guttapurcha with an heated instrument. A reamer can then be inserted to remove the guttapurcha and the direction of the canal is identified. Use of magnifying lens and fiber optic light is helpful in this process. After opening to the required length it is reamed to the appropriate size to accept a post. The minimum length required for a post hole is either the size of that tooth crown or two-thirds the length of the root whichever is longer.
Root canal- as the thickness of the remaining is the prime variable in fracture resistance of the root, care should be taken only to remove mimimal tooth structure from the canal. Over enlargement can perforate or weaken the root which may split while cementing the post.
Studies reveal that post of 1.8 mm diameter fracture more easily than those with 1.3 mm and also internal stresses are less with thinner posts. It is recommended to enlarge the root only the amount required because most of the roots are narrow mesio distally and also have proximal concavities where the remaining dentine is thin which can favor perforation by the post or acts as a fracture point.
Enlargement seldom needs to exceed once or twice additional file sizes beyond that used for endodontic treatment. so it is wise to check the treatment record of endodontic therapy for proper and limited enargement of the canal.
In most of the endodontically treated teeth the coronal part has been lost from caries, previous restoration or during access cavity opening so most tooth structure should be conserved as it helps in reducing the stress concentration at the gingival margins.
Indeed if more than 2 mm of coronal tooth is left the post design probably plays little role in the fracture resistance of the restored tooth. 1 mm of the vertical height of the crown provides FERRULE EFFECT.
Retention is mainly two types.\t\t
Active retention.: It is due to threads or the serrations or any irregularities present on the post surface.
Passive retention: It is due to the sealer or the cement used for the luting of the post.
Retention of the post is affected by preparation geometry, post length, post diameter, surface texture and luting agent.
Usual cause of loss of vitality of the posterior teeth is extensive caries, micro leakage beneath a large restoration. Therefore much of the central core of dentine is missing and the remaining enamel is undermined and weakened. so simple restoration of crown of the tooth with G I C OR COMPOSITE cannot impart sufficient strength to with stand laterally directed occlusal load. so it is desirable to rebuild with amalgam to support the posts before placing crown.
Ditches and grooves will help in retention but as there is little dentine left it is not possible to place them.
Relatively long posts with a circular cross section provide good retention and support in anterior teeth but should be avoided in posterior teeth which often have curved roots i.e. elliptical or ribbon shaped canals. so for these teeth retention is better provided by relatively short posts in the divergent canals.
If more than 4 mm of coronal tooth structure is remaining use of the root canal for retention is not necessary.
If a cast core is used it can be made in sections that have different paths of withdrawal.
One of the function of the post and core is to improve resistance to laterally directed forces by distributing them over as large as an area as possible.
According to studies
Stresses are more at shoulder and apex region.
Stresses can be decreased by increasing the post length.
Parallel sided posts distributes stresses more evenly than tapered posts[which has wedging effect]
Sharp angles should be avoided.
Rotation of the post can be prevented by axial walls.where more coronal tooth structure is present. When most of dentine is destroyed a small groove placed in the canal can serve as an anti rotational element. it should be placed in the bulkiest part of root [usually lingual side]. auxillary pins also acts as anti rotational elements. Alternatively rotation of the threaded post can be prevented by preparing a small cavity, half in the post and half in the root then condensing amalgam in to it after cementation of the post.
It involves 3 stages:
Removal of root canal material to appropriate depth
Enlargement of canal
Preparation of the coronal tooth structure
A post cannot be placed if the canal is filled with a full length silver point and these should be retreated with gutta purcha.
With a warm endodontic instrument and rotary instrument[some times with a chemical agent chloroform].
However warm method is preferred as it will not disturb the apical seal.
before removing the G.P. calculate the length of the post to be placed.
Make sure the post length equal to height of the anatomic crown or 2\\3 the length of the root whichever is longer.\t\t
Do not disturb the apical 4 to 5 mm of the G P. if this is not done the prognosis of the tooth is compromised.
If working length of the tooth is known the length of the post can be easily determined.
Then apply rubber dam to prevent aspiration. Select an condenser large enough to hold heat well, mark it at app length W.L minimum 5 mm and place in canal to soften the G P.
If GP is old and lost its thermoplasticity use rotary instrument. Make sure that instrument does not engage the dentine.
It was stated that gates glidden drill conforms to the original canal more consistently than the para post drill.
Choose the rotary slightly narrow than the canals.
Rotary should follow the centre of the gutta purcha preserving the dentine.
Rotary shoukd not be used immediately after obturation as it disturbs the apical seal.
After removing, shape the canal as needed. The purpose is to remove the undercuts and prepare the canal to receive the posts.
posts should not be no more than 1\\3 the diameter of the root dimension.
Prior to enlargement of the canal, decision must be made regarding the type of post used.
Parallel sided prefabricated posts are recommended for conservatively prepared root canals with circular cross section.
Flared canals can best be managed with custom made post.
Parallel sided posts are more retentive and distributes stresses better than tapered, but they do not conform to the shape of the canal. in this situation it may not be possible to enlarge the canal sufficiently for the post, then a tapered custom made post is preferred.
Tapered post better conform to the canal than parallel post but it is less retentive and will cause greater stress concentration although retention may be improved by controlled grooving.
These are used in canals that have a noncircular cross section or extreme taper.
Little preparation is sufficient for custom made post. i.e. removal of undercuts and additional shaping.
After post space is prepared then extracoronal restoration is done.
Anterior teeth requiring post and core can be best restored with metal ceramic crown
Prepare the remaining crown as it was an undamaged tooth.
Sufficient reduction in the facial surface gives good easthetics.
Remove the undercuts and undermined enamel
The prepared crown must be perpendicular to the post so that it can act as a positive stop and prevent over seating of tooth.
Rotation of the post can be prevented by preparing a flat surfaces parallel to the post and when little tooth structure remains an antirotational groove should be placed in the canal.
Complete the preparation by giving smooth finish lines.
The only advantage is simplicity of the technique.
Post is selected to match the canal and minimum adjustments are made to seat it.
Coronal part may not exactly fit and this is adjusted by adding material to the core while it is fabricated.
Available materials are pt- au- pd. \\ p-g-p,cr-co, s.s, ni- cr-ti and non oxidizing noble alloys.\t\t
Studies reveal that corrosion of these base metal leads to root fracture and this is attributed to the electrolytic action of the dissimilar metals used to the post and core which causes a v olume change that split the root.
Prefabricated posts have high modulous of elasticity, elongated grain structure which contributes to the physical properties as compared to cast posts and also more rigid.
These can be cast either by direct pattern or by indirect pattern.
In single canals ------direct pattern is used.
In multiple canals-----indirect pattern is used.
Lubricate the canal---select a dowel, it should extend full deapth of the canal. Apply resin [bead brush tech,]
Here resin can be applied in two types.
Applying at the orifice of the canal only
Resin is rolled and placed in canal
Now moisten the dowel with monomer and insert in the canal. Donot allow the resin to set fully and now loosen the dowel and reseat it. repeat this u ntill the resin sets. Remove the dowel. Trim any excess or undercuts on it…. the completed post pattern should not bind the canal.
Here a wire reinforcement should be done to prevent distortion and to get an accurate impression of the root canal.
An orthodontic wire cut in J shape is selected. it should be loosely fit in canal and must extend to full depth of the canal. Coat it with an adhesive. Lubricate the canal to facilitate removal of the wire.
Fill the canal with impression material using lentulo spiral. Seat the wire in the canal. Syringe more material around the wire and tooth and place the tray. Now remove the tray along with the post pattern. Evaluate it and pour the cast.
Using this cast take a plastic post or toothpick which extends full deapth, and apply sticy wax to it and seat it in the canal.like this wax pattern is fabricated. Which should completely adapt to post space.
Replace the missing coronal tooth structure, restoring its original anatomy. It can be shaped either in resin or wax which is added to the post before the assembly is casr in metal. This prevents failure at the post-core interface.
It can be cast on to the prefabricated post system or make the core with a plastic material like amalgam or G I C or composites.
Advantages with plastic materials.
Undercuts need not be removed. so tooth structure can be conserved.
Less visits to the patient.
Less lab procedure.
Good adaptation to the tooth structure.
Disadvantages:
No long term success due to corrosion.
Temperature fluctuations leads to micro leakage.
Difficulty may be encountered with rubber dam or matrix application.[with grossly decayed teeth].
Rubber dam is applied. Remove the G P cone from the pulp chamber. if crown structure is less than 4 mm remove the G P from the root canal up to 2–4 mm.
Remove the unfermined enamel and carious dentin.
When cusps are missing, pins are not usually required because adequate retention can be gained by extending the amalgam into the root canal.
When pulp chamber is thin, protect the chamber from condensing pressures while inserting the base. When lack of tooth structure makes the application of matrix difficult then apply orthodontic or copper band. Condense the materials into the canals with endodontic plugger.
Fill the pulp chamber and carve the amalgam to desired shape and make an impression.
Alternatively the amalgam can be built up to anatomic contour and later prepared for a compedte crown.under these circumstance care must be taken to avoid forces that would fracture the tooth or newly placed restoration.
Can be cast directly onto a prefabricated post.
An indirect procedure can be applied making restoration of posterior teeth easier.
High noble alloys can be used.
Take a pre fabricated post[metal or acrylic]
By bead technique apply resin to the post, light cure resin can also be used
Slightly overbuild the core and let it polymerize.shape the core with burs. Use water spray to prevent overheating of resin. if any defects correct it with wax.
Remove the pattern sprue it and invest it.
Both direct and indirect techniques can be used\t\t
Limited access makes the indirect tech easier.
Single core with auxiliary post can be used or multisection core can be used. Multisection is preffered in indirect approach.
Core is cast directly on to the post of one canal., while the other canals already have prefabricated posts that passes through the hole in the core.
Fit the prefabricated posts in the canals. One of the posts is roughened and others are smoothened. All the posts should extend beyond the preparation. Now build up the core with resin by bead tech. Shape the core and finish it.
Now grip the smoothened posts. With forceps and remove the post, invest and cast The core with the single rough post. After this the holes for the auxiliary posts can be refined with the appropriate twist drill. Verify it and cement the core and auxiliary posts to place.
Wax the custom made posts, build part of the core around the first post. Remove the undercuts adjacent to other post holes and cast the first section. Now wax the other section and cast them.
Use of dove tails to interlock the sections makes the procedure more complicated and is probably of limited benefit.
TO prevent drifting of opposing or adfacant teeth an endodontically treated teeth requires a proper provisional restoration immediately following completion of endodontic treatment
These provide good proximal contacts to prevent tooth migration leading to unwanted root proximity
The prepared prosthesis should fit some what loosely in the canal.tight fit may cause root fracture.
Casting should be slightly undersized which can be accomplished by restricting expansion of the invest ment [by omitting the ring liner or casting at a lower mold temperature.]
A sound casting technique is essential because any undetected porosity could lead to a weakened casting that might fail in function.
Care should be exercised such that casting defects should not interfere with seating of the post, lest root fracture results.
Post and core should be inserted with gentle pressure. no adjustments should be made immediately after cementation because vibration from the bur could fracture the setting cement and cause premature failure.
It is important that the luting agent should fill all the dead space within the root canal system. a rotary paste filler or cement tube is used to fill the canal.post and core is inserted gently to reduce hydrostatic pressure which could cause root fracture.
It is recommended that a groove placed along the side of the post to allow excess cement to escape, if a parallel sided post is being used.
Zinc phosphate: Solubility in oral fluids.
Polycarboxylate: Undergoes plastic deformation
Glass ionomer cement: Do not reach its maximum strength for many days. Therefore Any recontouring of the core may disturb the set of the cement and weaken the immature cement fibers.
Resin modified GIC: exhibits delayed expansion of the cement.
Occasionally a failed post and core must be removed, then if sufficient post length is exposed coronally, it can be retrieved with thin beaked forceps.
Vibrating the post with a ultrasonic scaler will weaken the cement and facilitates easy removal. Here a thin scaler tip is recommended or alternatively a post puller is used. [post puller cannot be used for fractured post.]
Fractured posts should be drilled out but care should be taken not to deviate from the canal. This is best limited to short fractured posts
He used a hallow end cutting tubes o r trephines to prepare a thin trench around the post. Post retrieved can be facilitated by using an adhesive to attach a hallow tube extractor or by using a threaded extractor.
Newer Concepts:
Zarow, M proposed new classification was to help the clinician to select the most appropriate treatment plan for restoring root filled teeth when choosing between a composite core alone, a composite core reinforced by fiber post, a gold cast post or implant treatment.
Class 0 (no post – composite core build-up).
Class 1 (fiber post).
Class 2 (pre-restorative procedures are needed: orthodontic extrusion or crown lengthening).
Class 3 (gold cast post).
Class 4 (extraction).
The three categories given by Motasum Abu-Awwad in 2019 are [75].
Minimally destructed teeth, which could be managed simply through intracoronal composite resin restorations.
Moderately destructed teeth, which could be managed through adhesive overlays
Severely destructed teeth, which could be managed through fiber post–core–crown combination, or through endocrowns [9].
Restoration of endodontically treated teeth can be done successfully if the available procedures are performed well.
Where most of the crown is preserved an anterior teeth can be safely restored with a plastic filling material.
To prevent fracture of posterior teeth, cast restoration with cuspal coverage is recommended.
Anterior teeth can best built up with a cast metal post and core or a metal core cast on to a prefabricated wire.
Amalgam can be used on posterior teeth, although if much coronal tooth structure is missing a casting may be preferred.
The rational for the post placement is two folds that is,\t\t
To retain the restoration, and.
To protect the remaining tooth structure.
The success rate will be high if the rationales for the results are understood, appreciated and propagated accordingly. A technique with more advantages and fewer disadvantages in the given restoration should be chosen. It is important to preserve as much tooth structure as possible, particularly in the root canal. The post should be adequate length for good stress distribution but not as long as to jeopardize the apical seal. In the final analysis the quality of the root canal thereby combined with the quality of its final restoration determines the clinical success of pulpless tooth with post and core.
I am thankful to Rural Dental College,Pravara institute of medical sciences,Loni. Dr.Mukund Singh, Dr.Milind Jagdale, Dr.Agey Pathak.
None.
"Open access contributes to scientific excellence and integrity. It opens up research results to wider analysis. It allows research results to be reused for new discoveries. And it enables the multi-disciplinary research that is needed to solve global 21st century problems. Open access connects science with society. It allows the public to engage with research. To go behind the headlines. And look at the scientific evidence. And it enables policy makers to draw on innovative solutions to societal challenges".
\n\nCarlos Moedas, the European Commissioner for Research Science and Innovation at the STM Annual Frankfurt Conference, October 2016.
",metaTitle:"About Open Access",metaDescription:"Open access contributes to scientific excellence and integrity. It opens up research results to wider analysis. It allows research results to be reused for new discoveries. And it enables the multi-disciplinary research that is needed to solve global 21st century problems. Open access connects science with society. It allows the public to engage with research. To go behind the headlines. And look at the scientific evidence. And it enables policy makers to draw on innovative solutions to societal challenges.\n\nCarlos Moedas, the European Commissioner for Research Science and Innovation at the STM Annual Frankfurt Conference, October 2016.",metaKeywords:null,canonicalURL:"about-open-access",contentRaw:'[{"type":"htmlEditorComponent","content":"The Open Access publishing movement started in the early 2000s when academic leaders from around the world participated in the formation of the Budapest Initiative. They developed recommendations for an Open Access publishing process, “which has worked for the past decade to provide the public with unrestricted, free access to scholarly research—much of which is publicly funded. Making the research publicly available to everyone—free of charge and without most copyright and licensing restrictions—will accelerate scientific research efforts and allow authors to reach a larger number of readers” (reference: http://www.budapestopenaccessinitiative.org)
\\n\\nIntechOpen’s co-founders, both scientists themselves, created the company while undertaking research in robotics at Vienna University. Their goal was to spread research freely “for scientists, by scientists’ to the rest of the world via the Open Access publishing model. The company soon became a signatory of the Budapest Initiative, which currently has more than 1000 supporting organizations worldwide, ranging from universities to funders.
\\n\\nAt IntechOpen today, we are still as committed to working with organizations and people who care about scientific discovery, to putting the academic needs of the scientific community first, and to providing an Open Access environment where scientists can maximize their contribution to scientific advancement. By opening up access to the world’s scientific research articles and book chapters, we aim to facilitate greater opportunity for collaboration, scientific discovery and progress. We subscribe wholeheartedly to the Open Access definition:
\\n\\n“By “open access” to [peer-reviewed research literature], we mean its free availability on the public internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself. The only constraint on reproduction and distribution, and the only role for copyright in this domain, should be to give authors control over the integrity of their work and the right to be properly acknowledged and cited” (reference: http://www.budapestopenaccessinitiative.org)
\\n\\nOAI-PMH
\\n\\nAs a firm believer in the wider dissemination of knowledge, IntechOpen supports the Open Access Initiative Protocol for Metadata Harvesting (OAI-PMH Version 2.0). Read more
\\n\\nLicense
\\n\\nBook chapters published in edited volumes are distributed under the Creative Commons Attribution 3.0 Unported License (CC BY 3.0). IntechOpen upholds a very flexible Copyright Policy. There is no copyright transfer to the publisher and Authors retain exclusive copyright to their work. All Monographs/Compacts are distributed under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Read more
\\n\\nPeer Review Policies
\\n\\nAll scientific works are Peer Reviewed prior to publishing. Read more
\\n\\nOA Publishing Fees
\\n\\nThe Open Access publishing model employed by IntechOpen eliminates subscription charges and pay-per-view fees, enabling readers to access research at no cost. In order to sustain operations and keep our publications freely accessible we levy an Open Access Publishing Fee for manuscripts, which helps us cover the costs of editorial work and the production of books. Read more
\\n\\nDigital Archiving Policy
\\n\\nIntechOpen is committed to ensuring the long-term preservation and the availability of all scholarly research we publish. We employ a variety of means to enable us to deliver on our commitments to the scientific community. Apart from preservation by the Croatian National Library (for publications prior to April 18, 2018) and the British Library (for publications after April 18, 2018), our entire catalogue is preserved in the CLOCKSS archive.
\\n\\nOpen Science is transparent and accessible knowledge that is shared and developed through collaborative networks.
\\n\\nOpen Science is about increased rigour, accountability, and reproducibility for research. It is based on the principles of inclusion, fairness, equity, and sharing, and ultimately seeks to change the way research is done, who is involved and how it is valued. It aims to make research more open to participation, review/refutation, improvement and (re)use for the world to benefit.
\\n\\nOpen Science refers to doing traditional science with more transparency involved at various stages, for example by openly sharing code and data. It implies a growing set of practices - within different disciplines - aiming at:
\\n\\nWe aim at improving the quality and availability of scholarly communication by promoting and practicing:
\\n\\n\\n"}]'},components:[{type:"htmlEditorComponent",content:'
The Open Access publishing movement started in the early 2000s when academic leaders from around the world participated in the formation of the Budapest Initiative. They developed recommendations for an Open Access publishing process, “which has worked for the past decade to provide the public with unrestricted, free access to scholarly research—much of which is publicly funded. Making the research publicly available to everyone—free of charge and without most copyright and licensing restrictions—will accelerate scientific research efforts and allow authors to reach a larger number of readers” (reference: http://www.budapestopenaccessinitiative.org)
\n\nIntechOpen’s co-founders, both scientists themselves, created the company while undertaking research in robotics at Vienna University. Their goal was to spread research freely “for scientists, by scientists’ to the rest of the world via the Open Access publishing model. The company soon became a signatory of the Budapest Initiative, which currently has more than 1000 supporting organizations worldwide, ranging from universities to funders.
\n\nAt IntechOpen today, we are still as committed to working with organizations and people who care about scientific discovery, to putting the academic needs of the scientific community first, and to providing an Open Access environment where scientists can maximize their contribution to scientific advancement. By opening up access to the world’s scientific research articles and book chapters, we aim to facilitate greater opportunity for collaboration, scientific discovery and progress. We subscribe wholeheartedly to the Open Access definition:
\n\n“By “open access” to [peer-reviewed research literature], we mean its free availability on the public internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself. The only constraint on reproduction and distribution, and the only role for copyright in this domain, should be to give authors control over the integrity of their work and the right to be properly acknowledged and cited” (reference: http://www.budapestopenaccessinitiative.org)
\n\nOAI-PMH
\n\nAs a firm believer in the wider dissemination of knowledge, IntechOpen supports the Open Access Initiative Protocol for Metadata Harvesting (OAI-PMH Version 2.0). Read more
\n\nLicense
\n\nBook chapters published in edited volumes are distributed under the Creative Commons Attribution 3.0 Unported License (CC BY 3.0). IntechOpen upholds a very flexible Copyright Policy. There is no copyright transfer to the publisher and Authors retain exclusive copyright to their work. All Monographs/Compacts are distributed under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Read more
\n\nPeer Review Policies
\n\nAll scientific works are Peer Reviewed prior to publishing. Read more
\n\nOA Publishing Fees
\n\nThe Open Access publishing model employed by IntechOpen eliminates subscription charges and pay-per-view fees, enabling readers to access research at no cost. In order to sustain operations and keep our publications freely accessible we levy an Open Access Publishing Fee for manuscripts, which helps us cover the costs of editorial work and the production of books. Read more
\n\nDigital Archiving Policy
\n\nIntechOpen is committed to ensuring the long-term preservation and the availability of all scholarly research we publish. We employ a variety of means to enable us to deliver on our commitments to the scientific community. Apart from preservation by the Croatian National Library (for publications prior to April 18, 2018) and the British Library (for publications after April 18, 2018), our entire catalogue is preserved in the CLOCKSS archive.
\n\nOpen Science is transparent and accessible knowledge that is shared and developed through collaborative networks.
\n\nOpen Science is about increased rigour, accountability, and reproducibility for research. It is based on the principles of inclusion, fairness, equity, and sharing, and ultimately seeks to change the way research is done, who is involved and how it is valued. It aims to make research more open to participation, review/refutation, improvement and (re)use for the world to benefit.
\n\nOpen Science refers to doing traditional science with more transparency involved at various stages, for example by openly sharing code and data. It implies a growing set of practices - within different disciplines - aiming at:
\n\nWe aim at improving the quality and availability of scholarly communication by promoting and practicing:
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His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. 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Preclinical data from rodent model of high fat diet-induced obesity collectively suggest that CAP exerts its effects by activating TRPV1 signaling pathway, which stimulates thermogenic mechanisms in the white and brown adipose tissues to induce browning of white adipose tissues and brown adipose tissue thermogenesis. This leads to enhancement of metabolic activity and thermogenesis to counter obesity. Although CAP and its pungent and non-pungent analogs are used in human clinical studies, their effects on satiety and energy expenditure have been the highlights of such studies. The precise mechanism of action of CAP has not been evaluated in humans. This article summarizes these data and suggests that long-term safety and tolerance studies are important for advancing CAP to treat human obesity.",book:{id:"6810",slug:"capsaicin-and-its-human-therapeutic-development",title:"Capsaicin and its Human Therapeutic Development",fullTitle:"Capsaicin and its Human Therapeutic Development"},signatures:"Baskaran Thyagarajan, Vivek Krishnan and Padmamalini Baskaran",authors:null},{id:"61453",title:"A Matter of Taste: Capsaicinoid Diversity in Chile Peppers and the Importance to Human Food Preference",slug:"a-matter-of-taste-capsaicinoid-diversity-in-chile-peppers-and-the-importance-to-human-food-preferenc",totalDownloads:1301,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"Chile peppers are valued worldwide for their distinct capsaicinoid compounds that have been used traditionally in medicine and culinary practices. With 32 known species, five of them domesticated, they provide unique chemical profiles, when consumed by humans. Capsaicinoids, the spicy compounds, are alkaloids used to deter herbivory in the wild, offering protection to the chile pepper fruit seeds. Among the 22 known capsaicinoid structures, capsaicin and dihydrocapsaicin are normally the most abundant. In humans, capsaicin binds to nociceptor TRPV1 that generates a heat sensation. Capsaicin also mitigates inflammation responses in the digestive tract and has the potential to aid in nutrient absorption. Distinct heat profiles were recently described for the five domesticated Capsicum species showing a difference in heat sensations specific to species and pod type. Due to the many capsaicinoid structures, we explore the implications and opportunities of having a diverse array of heat profiles in genetically diverse Capsicum species.",book:{id:"6810",slug:"capsaicin-and-its-human-therapeutic-development",title:"Capsaicin and its Human Therapeutic Development",fullTitle:"Capsaicin and its Human Therapeutic Development"},signatures:"Ivette Guzmán and Paul W. 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The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"7",title:"Biomedical Engineering",doi:"10.5772/intechopen.71985",issn:"2631-5343",scope:"Biomedical Engineering is one of the fastest-growing interdisciplinary branches of science and industry. The combination of electronics and computer science with biology and medicine has improved patient diagnosis, reduced rehabilitation time, and helped to facilitate a better quality of life. Nowadays, all medical imaging devices, medical instruments, or new laboratory techniques result from the cooperation of specialists in various fields. The series of Biomedical Engineering books covers such areas of knowledge as chemistry, physics, electronics, medicine, and biology. 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Dr. Koprowski has authored more than a hundred research papers with dozens in impact factor (IF) journals and has authored or co-authored six books. Additionally, he is the author of several national and international patents in the field of biomedical devices and imaging. Since 2011, he has been a reviewer of grants and projects (including EU projects) in biomedical engineering.",institutionString:null,institution:{name:"University of Silesia",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:3,paginationItems:[{id:"7",title:"Bioinformatics and Medical Informatics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",isOpenForSubmission:!0,editor:{id:"351533",title:"Dr.",name:"Slawomir",middleName:null,surname:"Wilczynski",slug:"slawomir-wilczynski",fullName:"Slawomir Wilczynski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035U1loQAC/Profile_Picture_1630074514792",biography:"Professor Sławomir Wilczyński, Head of the Chair of Department of Basic Biomedical Sciences, Faculty of Pharmaceutical Sciences, Medical University of Silesia in Katowice, Poland. His research interests are focused on modern imaging methods used in medicine and pharmacy, including in particular hyperspectral imaging, dynamic thermovision analysis, high-resolution ultrasound, as well as other techniques such as EPR, NMR and hemispheric directional reflectance. Author of over 100 scientific works, patents and industrial designs. Expert of the Polish National Center for Research and Development, Member of the Investment Committee in the Bridge Alfa NCBiR program, expert of the Polish Ministry of Funds and Regional Policy, Polish Medical Research Agency. 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He completed a one-year Post-Doctoral Fellowship awarded by the DFAIT (Foreign Affairs and International Trade Canada) at the Institute of Biomedical Engineering of the University of New Brunswick (Canada) in 2010. Currently, he is Professor in the Faculty of Electrical Engineering (UFU). He has authored and co-authored more than 200 peer-reviewed publications in Biomedical Engineering. He has been a researcher of The National Council for Scientific and Technological Development (CNPq-Brazil) since 2009. He has served as an ad-hoc consultant for CNPq, CAPES (Coordination for the Improvement of Higher Education Personnel), FINEP (Brazilian Innovation Agency), and other funding bodies on several occasions. He was the Secretary of the Brazilian Society of Biomedical Engineering (SBEB) from 2015 to 2016, President of SBEB (2017-2018) and Vice-President of SBEB (2019-2020). He was the head of the undergraduate program in Biomedical Engineering of the Federal University of Uberlândia (2015 - June/2019) and the head of the Centre for Innovation and Technology Assessment in Health (NIATS/UFU) since 2010. He is the head of the Postgraduate Program in Biomedical Engineering (UFU, July/2019 - to date). He was the secretary of the Parkinson's Disease Association of Uberlândia (2018-2019). Dr. Andrade's primary area of research is focused towards getting information from the neuromuscular system to understand its strategies of organization, adaptation and controlling in the context of motor neuron diseases. His research interests include Biomedical Signal Processing and Modelling, Assistive Technology, Rehabilitation Engineering, Neuroengineering and Parkinson's Disease.",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",isOpenForSubmission:!0,editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",slug:"luis-villarreal-gomez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",biography:"Dr. Luis Villarreal is a research professor from the Facultad de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Tijuana, Baja California, México. Dr. Villarreal is the editor in chief and founder of the Revista de Ciencias Tecnológicas (RECIT) (https://recit.uabc.mx/) and is a member of several editorial and reviewer boards for numerous international journals. He has published more than thirty international papers and reviewed more than ninety-two manuscripts. 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His fields of interest are anterior segment disease, keratoconus, glaucoma, corneal dystrophies, and cataracts. His research topics include\nintraocular lens power calculation, eye modification induced by refractive surgery, glaucoma progression, and validation of new diagnostic devices in ophthalmology. \nHe has published more than 100 papers in international and Italian scientific journals, more than 60 in journals with impact factors, and chapters in international and Italian books. He has also edited two international books and authored more than 150 communications or posters for the most important international and Italian ophthalmology conferences.",institutionString:'University of Campania "Luigi Vanvitelli"',institution:{name:'University of Campania "Luigi Vanvitelli"',institutionURL:null,country:{name:"Italy"}}}]},{type:"book",id:"7560",title:"Non-Invasive Diagnostic Methods",subtitle:"Image Processing",coverURL:"https://cdn.intechopen.com/books/images_new/7560.jpg",slug:"non-invasive-diagnostic-methods-image-processing",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Mariusz Marzec and Robert Koprowski",hash:"d92fd8cf5a90a47f2b8a310837a5600e",volumeInSeries:3,fullTitle:"Non-Invasive Diagnostic Methods - Image Processing",editors:[{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:{name:"University of Silesia",institutionURL:null,country:{name:"Poland"}}}]},{type:"book",id:"6843",title:"Biomechanics",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6843.jpg",slug:"biomechanics",publishedDate:"January 30th 2019",editedByType:"Edited by",bookSignature:"Hadi Mohammadi",hash:"85132976010be1d7f3dbd88662b785e5",volumeInSeries:4,fullTitle:"Biomechanics",editors:[{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. 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Then take a masters degree in science in Germany (Animal breeding). Take a doctorate in animal science at the UANL.",institutionString:null,institution:{name:"Universidad Autónoma de Nuevo León",country:{name:"Mexico"}}},{id:"309250",title:"Dr.",name:"Miguel",middleName:null,surname:"Quaresma",slug:"miguel-quaresma",fullName:"Miguel Quaresma",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/309250/images/9059_n.jpg",biography:"Miguel Nuno Pinheiro Quaresma was born on May 26, 1974 in Dili, Timor Island. He is married with two children: a boy and a girl, and he is a resident in Vila Real, Portugal. He graduated in Veterinary Medicine in August 1998 and obtained his Ph.D. degree in Veterinary Sciences -Clinical Area in February 2015, both from the University of Trás-os-Montes e Alto Douro. He is currently enrolled in the Alternative Residency of the European College of Animal Reproduction. 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(2002), and Ph.D. (2008) degrees in Veterinary Medicine, Animal Pathology and Veterinary Microbiology from College of Veterinary Medicine, Addis Ababa University, Ethiopia; College of Veterinary Medicine, Utrecht University, the Netherlands and Western College of Veterinary Medicine, University of Saskatchewan, Canada respectively. He did his Postdoctoral training in microbial pathogenesis (2009 - 2015) in the Department of Animal Science, the University of Tennessee, Institute of Agriculture, Knoxville, Tennessee. Dr. Kerro Dego’s research focuses on the prevention and control of infectious diseases of farm animals, particularly mastitis, improving dairy food safety, and mitigation of antimicrobial resistance. Dr. Kerro Dego has extensive experience in studying the pathogenesis of bacterial infections, identification of virulence factors, and vaccine development and efficacy testing against major bacterial mastitis pathogens. Dr. Kerro Dego conducted numerous controlled experimental and field vaccine efficacy studies, vaccination, and evaluation of immunological responses in several species of animals, including rodents (mice) and large animals (bovine and ovine).",institutionString:"University of Tennessee at Knoxville",institution:{name:"University of Tennessee at Knoxville",country:{name:"United States of America"}}},{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón Poggi",slug:"juan-carlos-gardon-poggi",fullName:"Juan Carlos Gardón Poggi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",biography:"Juan Carlos Gardón Poggi received University degree from the Faculty of Agrarian Science in Argentina, in 1983. Also he received Masters Degree and PhD from Córdoba University, Spain. He is currently a Professor at the Catholic University of Valencia San Vicente Mártir, at the Department of Medicine and Animal Surgery. He teaches diverse courses in the field of Animal Reproduction and he is the Director of the Veterinary Farm. He also participates in academic postgraduate activities at the Veterinary Faculty of Murcia University, Spain. His research areas include animal physiology, physiology and biotechnology of reproduction either in males or females, the study of gametes under in vitro conditions and the use of ultrasound as a complement to physiological studies and development of applied biotechnologies. Routinely, he supervises students preparing their doctoral, master thesis or final degree projects.",institutionString:null,institution:{name:"Valencia Catholic University Saint Vincent Martyr",country:{name:"Spain"}}},{id:"309529",title:"Dr.",name:"Albert",middleName:null,surname:"Rizvanov",slug:"albert-rizvanov",fullName:"Albert Rizvanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/309529/images/9189_n.jpg",biography:'Albert A. Rizvanov is a Professor and Director of the Center for Precision and Regenerative Medicine at the Institute of Fundamental Medicine and Biology, Kazan Federal University (KFU), Russia. He is the Head of the Center of Excellence “Regenerative Medicine” and Vice-Director of Strategic Academic Unit \\"Translational 7P Medicine\\". Albert completed his Ph.D. at the University of Nevada, Reno, USA and Dr.Sci. at KFU. He is a corresponding member of the Tatarstan Academy of Sciences, Russian Federation. Albert is an author of more than 300 peer-reviewed journal articles and 22 patents. He has supervised 11 Ph.D. and 2 Dr.Sci. dissertations. Albert is the Head of the Dissertation Committee on Biochemistry, Microbiology, and Genetics at KFU.\nORCID https://orcid.org/0000-0002-9427-5739\nWebsite https://kpfu.ru/Albert.Rizvanov?p_lang=2',institutionString:"Kazan Federal University",institution:{name:"Kazan Federal University",country:{name:"Russia"}}},{id:"210551",title:"Dr.",name:"Arbab",middleName:null,surname:"Sikandar",slug:"arbab-sikandar",fullName:"Arbab Sikandar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210551/images/system/210551.jpg",biography:"Dr. Arbab Sikandar, PhD, M. Phil, DVM was born on April 05, 1981. He is currently working at the College of Veterinary & Animal Sciences as an Assistant Professor. He previously worked as a lecturer at the same University. \nHe is a Member/Secretory of Ethics committee (No. CVAS-9377 dated 18-04-18), Member of the QEC committee CVAS, Jhang (Regr/Gen/69/873, dated 26-10-2017), Member, Board of studies of Department of Basic Sciences (No. CVAS. 2851 Dated. 12-04-13, and No. CVAS, 9024 dated 20/11/17), Member of Academic Committee, CVAS, Jhang (No. CVAS/2004, Dated, 25-08-12), Member of the technical committee (No. CVAS/ 4085, dated 20,03, 2010 till 2016).\n\nDr. Arbab Sikandar contributed in five days hands-on-training on Histopathology at the Department of Pathology, UVAS from 12-16 June 2017. He received a Certificate of appreciation for contributions for Popularization of Science and Technology in the Society on 17-11-15. He was the resource person in the lecture series- ‘scientific writing’ at the Department of Anatomy and Histology, UVAS, Lahore on 29th October 2015. He won a full fellowship as a principal candidate for the year 2015 in the field of Agriculture, EICA, Egypt with ref. to the Notification No. 12(11) ACS/Egypt/2014 from 10 July 2015 to 25th September 2015.; he received a grant of Rs. 55000/- as research incentives from Director, Advanced Studies and Research, UVAS, Lahore upon publications of research papers in IF Journals (DR/215, dated 19-5-2014.. He obtained his PhD by winning a HEC Pakistan indigenous Scholarship, ‘Ph.D. fellowship for 5000 scholars – Phase II’ (2av1-147), 17-6/HEC/HRD/IS-II/12, November 15, 2012. \n\nDr. Sikandar is a member of numerous societies: Registered Veterinary Medical Practitioner (life member) and Registered Veterinary Medical Faculty of Pakistan Veterinary Medical Council. The Registration code of PVMC is RVMP/4298 and RVMF/ 0102.; Life member of the University of Veterinary and Animal Sciences, Lahore, Alumni Association with S# 664, dated: 6-4-12. ; Member 'Vets Care Organization Pakistan” with Reference No. VCO-605-149, dated 05-04-06. :Member 'Vet Crescent” (Society of Animal Health and Production), UVAS, Lahore.",institutionString:"University of Veterinary & Animal Science",institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}},{id:"311663",title:"Dr.",name:"Prasanna",middleName:null,surname:"Pal",slug:"prasanna-pal",fullName:"Prasanna Pal",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311663/images/13261_n.jpg",biography:null,institutionString:null,institution:{name:"National Dairy Research Institute",country:{name:"India"}}},{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",biography:"Catrin Rutland is an Associate Professor of Anatomy and Developmental Genetics at the University of Nottingham, UK. She obtained a BSc from the University of Derby, England, a master’s degree from Technische Universität München, Germany, and a Ph.D. from the University of Nottingham. She undertook a post-doctoral research fellowship in the School of Medicine before accepting tenure in Veterinary Medicine and Science. Dr. Rutland also obtained an MMedSci (Medical Education) and a Postgraduate Certificate in Higher Education (PGCHE). She is the author of more than sixty peer-reviewed journal articles, twelve books/book chapters, and more than 100 research abstracts in cardiovascular biology and oncology. She is a board member of the European Association of Veterinary Anatomists, Fellow of the Anatomical Society, and Senior Fellow of the Higher Education Academy. Dr. Rutland has also written popular science books for the public. https://orcid.org/0000-0002-2009-4898. www.nottingham.ac.uk/vet/people/catrin.rutland",institutionString:null,institution:{name:"University of Nottingham",country:{name:"United Kingdom"}}},{id:"283315",title:"Prof.",name:"Samir",middleName:null,surname:"El-Gendy",slug:"samir-el-gendy",fullName:"Samir El-Gendy",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRduYQAS/Profile_Picture_1606215849748",biography:"Samir El-Gendy is a Professor of anatomy and embryology at the faculty of veterinary medicine, Alexandria University, Egypt. Samir obtained his PhD in veterinary science in 2007 from the faculty of veterinary medicine, Alexandria University and has been a professor since 2017. Samir is an author on 24 articles at Scopus and 12 articles within local journals and 2 books/book chapters. His research focuses on applied anatomy, imaging techniques and computed tomography. Samir worked as a member of different local projects on E-learning and he is a board member of the African Association of Veterinary Anatomists and of anatomy societies and as an associated author at local and international journals. Orcid: https://orcid.org/0000-0002-6180-389X",institutionString:null,institution:{name:"Alexandria University",country:{name:"Egypt"}}},{id:"246149",title:"Dr.",name:"Valentina",middleName:null,surname:"Kubale",slug:"valentina-kubale",fullName:"Valentina Kubale",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246149/images/system/246149.jpg",biography:"Valentina Kubale is Associate Professor of Veterinary Medicine at the Veterinary Faculty, University of Ljubljana, Slovenia. Since graduating from the Veterinary faculty she obtained her PhD in 2007, performed collaboration with the Department of Pharmacology, University of Copenhagen, Denmark. She continued as a post-doctoral fellow at the University of Copenhagen with a Lundbeck foundation fellowship. She is the editor of three books and author/coauthor of 23 articles in peer-reviewed scientific journals, 16 book chapters, and 68 communications at scientific congresses. Since 2008 she has been the Editor Assistant for the Slovenian Veterinary Research journal. She is a member of Slovenian Biochemical Society, The Endocrine Society, European Association of Veterinary Anatomists and Society for Laboratory Animals, where she is board member.",institutionString:"University of Ljubljana",institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"258334",title:"Dr.",name:"Carlos Eduardo",middleName:null,surname:"Fonseca-Alves",slug:"carlos-eduardo-fonseca-alves",fullName:"Carlos Eduardo Fonseca-Alves",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/258334/images/system/258334.jpg",biography:"Dr. Fonseca-Alves earned his DVM from Federal University of Goias – UFG in 2008. He completed an internship in small animal internal medicine at UPIS university in 2011, earned his MSc in 2013 and PhD in 2015 both in Veterinary Medicine at Sao Paulo State University – UNESP. Dr. Fonseca-Alves currently serves as an Assistant Professor at Paulista University – UNIP teaching small animal internal medicine.",institutionString:null,institution:{name:"Universidade Paulista",country:{name:"Brazil"}}},{id:"245306",title:"Dr.",name:"María Luz",middleName:null,surname:"Garcia Pardo",slug:"maria-luz-garcia-pardo",fullName:"María Luz Garcia Pardo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/245306/images/system/245306.png",biography:"María de la Luz García Pardo is an agricultural engineer from Universitat Politècnica de València, Spain. She has a Ph.D. in Animal Genetics. Currently, she is a lecturer at the Agrofood Technology Department of Miguel Hernández University, Spain. Her research is focused on genetics and reproduction in rabbits. The major goal of her research is the genetics of litter size through novel methods such as selection by the environmental sensibility of litter size, with forays into the field of animal welfare by analysing the impact on the susceptibility to diseases and stress of the does. Details of her publications can be found at https://orcid.org/0000-0001-9504-8290.",institutionString:null,institution:{name:"Miguel Hernandez University",country:{name:"Spain"}}},{id:"350704",title:"M.Sc.",name:"Camila",middleName:"Silva Costa",surname:"Ferreira",slug:"camila-ferreira",fullName:"Camila Ferreira",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/350704/images/17280_n.jpg",biography:"Graduated in Veterinary Medicine at the Fluminense Federal University, specialist in Equine Reproduction at the Brazilian Veterinary Institute (IBVET) and Master in Clinical Veterinary Medicine and Animal Reproduction at the Fluminense Federal University. She has experience in analyzing zootechnical indices in dairy cattle and organizing events related to Veterinary Medicine through extension grants. I have experience in the field of diagnostic imaging and animal reproduction in veterinary medicine through monitoring and scientific initiation scholarships. I worked at the Equus Central Reproduction Equine located in Santo Antônio de Jesus – BA in the 2016/2017 breeding season. I am currently a doctoral student with a scholarship from CAPES of the Postgraduate Program in Veterinary Medicine (Pathology and Clinical Sciences) at the Federal Rural University of Rio de Janeiro (UFRRJ) with a research project with an emphasis on equine endometritis.",institutionString:null,institution:null},{id:"41319",title:"Prof.",name:"Lung-Kwang",middleName:null,surname:"Pan",slug:"lung-kwang-pan",fullName:"Lung-Kwang Pan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41319/images/84_n.jpg",biography:null,institutionString:null,institution:null},{id:"125292",title:"Dr.",name:"Katy",middleName:null,surname:"Satué Ambrojo",slug:"katy-satue-ambrojo",fullName:"Katy Satué Ambrojo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/125292/images/system/125292.jpeg",biography:"Katy Satué Ambrojo received her Veterinary Medicine degree, Master degree in Equine Technology and doctorate in Veterinary Medicine from the Faculty of Veterinary, CEU-Cardenal Herrera University in Valencia, Spain.Dr. Satué is accredited as a Private University Doctor Professor, Doctor Assistant, and Contracted Doctor by AVAP (Agència Valenciana d'Avaluació i Prospectiva) and currently, as a full professor by ANECA (since January 2022). To date, Katy has taught 22 years in the Department of Animal Medicine and Surgery at the CEU-Cardenal Herrera University in undergraduate courses in Veterinary Medicine (General Pathology, integrated into the Applied Basis of Veterinary Medicine module of the 2nd year, Clinical Equine I of 3rd year, and Equine Clinic II of 4th year). Dr. Satué research activity is in the field of Endocrinology, Hematology, Biochemistry, and Immunology in the Spanish Purebred mare. She has directed 5 Doctoral Theses and 5 Diplomas of Advanced Studies, and participated in 11 research projects as a collaborating researcher. She has written 2 books and 14 book chapters in international publishers related to the area, and 68 scientific publications in international journals. Dr. Satué has attended 63 congresses, participating with 132 communications in international congresses and 19 in national congresses related to the area. Dr. Satué is a scientific reviewer for various prestigious international journals such as Animals, American Journal of Obstetrics and Gynecology, Veterinary Clinical Pathology, Journal of Equine Veterinary Science, Reproduction in Domestic Animals, Research Veterinary Science, Brazilian Journal of Medical and Biological Research, Livestock Production Science and Theriogenology, among others. Since 2014 she has been responsible for the Clinical Analysis Laboratory of the CEU-Cardenal Herrera University Veterinary Clinical Hospital.",institutionString:null,institution:null},{id:"201721",title:"Dr.",name:"Beatrice",middleName:null,surname:"Funiciello",slug:"beatrice-funiciello",fullName:"Beatrice Funiciello",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/201721/images/11089_n.jpg",biography:"Graduated from the University of Milan in 2011, my post-graduate education included CertAVP modules mainly on equines (dermatology and internal medicine) and a few on small animal (dermatology and anaesthesia) at the University of Liverpool. After a general CertAVP (2015) I gained the designated Certificate in Veterinary Dermatology (2017) after taking the synoptic examination and then applied for the RCVS ADvanced Practitioner status. After that, I completed the Postgraduate Diploma in Veterinary Professional Studies at the University of Liverpool (2018). My main area of work is cross-species veterinary dermatology.",institutionString:null,institution:null},{id:"291226",title:"Dr.",name:"Monica",middleName:null,surname:"Cassel",slug:"monica-cassel",fullName:"Monica Cassel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/291226/images/8232_n.jpg",biography:'Degree in Biological Sciences at the Federal University of Mato Grosso with scholarship for Scientific Initiation by FAPEMAT (2008/1) and CNPq (2008/2-2009/2): Project \\"Histological evidence of reproductive activity in lizards of the Manso region, Chapada dos Guimarães, Mato Grosso, Brazil\\". Master\\\'s degree in Ecology and Biodiversity Conservation at Federal University of Mato Grosso with a scholarship by CAPES/REUNI program: Project \\"Reproductive biology of Melanorivulus punctatus\\". PhD\\\'s degree in Science (Cell and Tissue Biology Area) \n at University of Sao Paulo with scholarship granted by FAPESP; Project \\"Development of morphofunctional changes in ovary of Astyanax altiparanae Garutti & Britski, 2000 (Teleostei, Characidae)\\". She has experience in Reproduction of vertebrates and Morphology, with emphasis in Cellular Biology and Histology. She is currently a teacher in the medium / technical level courses at IFMT-Alta Floresta, as well as in the Bachelor\\\'s degree in Animal Science and in the Bachelor\\\'s degree in Business.',institutionString:null,institution:null},{id:"442807",title:"Dr.",name:"Busani",middleName:null,surname:"Moyo",slug:"busani-moyo",fullName:"Busani Moyo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Gwanda State University",country:{name:"Zimbabwe"}}},{id:"439435",title:"Dr.",name:"Feda S.",middleName:null,surname:"Aljaser",slug:"feda-s.-aljaser",fullName:"Feda S. Aljaser",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"423023",title:"Dr.",name:"Yosra",middleName:null,surname:"Soltan",slug:"yosra-soltan",fullName:"Yosra Soltan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Alexandria University",country:{name:"Egypt"}}},{id:"349788",title:"Dr.",name:"Florencia Nery",middleName:null,surname:"Sompie",slug:"florencia-nery-sompie",fullName:"Florencia Nery Sompie",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sam Ratulangi University",country:{name:"Indonesia"}}},{id:"428600",title:"MSc.",name:"Adriana",middleName:null,surname:"García-Alarcón",slug:"adriana-garcia-alarcon",fullName:"Adriana García-Alarcón",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"428599",title:"MSc.",name:"Gabino",middleName:null,surname:"De La Rosa-Cruz",slug:"gabino-de-la-rosa-cruz",fullName:"Gabino De La Rosa-Cruz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"428601",title:"MSc.",name:"Juan Carlos",middleName:null,surname:"Campuzano-Caballero",slug:"juan-carlos-campuzano-caballero",fullName:"Juan Carlos Campuzano-Caballero",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}}]}},subseries:{item:{id:"95",type:"subseries",title:"Urban Planning and Environmental Management",keywords:"Circular Economy, Contingency Planning and Response to Disasters, Ecosystem Services, Integrated Urban Water Management, Nature-based Solutions, Sustainable Urban Development, Urban Green Spaces",scope:"