Hypertension prevalence in CKD patients.
\\n\\n
IntechOpen Book Series will also publish a program of research-driven Thematic Edited Volumes that focus on specific areas and allow for a more in-depth overview of a particular subject.
\\n\\nIntechOpen Book Series will be launching regularly to offer our authors and editors exciting opportunities to publish their research Open Access. We will begin by relaunching some of our existing Book Series in this innovative book format, and will expand in 2022 into rapidly growing research fields that are driving and advancing society.
\\n\\nLaunching 2021
\\n\\nArtificial Intelligence, ISSN 2633-1403
\\n\\nVeterinary Medicine and Science, ISSN 2632-0517
\\n\\nBiochemistry, ISSN 2632-0983
\\n\\nBiomedical Engineering, ISSN 2631-5343
\\n\\nInfectious Diseases, ISSN 2631-6188
\\n\\nPhysiology (Coming Soon)
\\n\\nDentistry (Coming Soon)
\\n\\nWe invite you to explore our IntechOpen Book Series, find the right publishing program for you and reach your desired audience in record time.
\\n\\nNote: Edited in October 2021
\\n"}]',published:!0,mainMedia:{caption:"",originalUrl:"/media/original/132"}},components:[{type:"htmlEditorComponent",content:'With the desire to make book publishing more relevant for the digital age and offer innovative Open Access publishing options, we are thrilled to announce the launch of our new publishing format: IntechOpen Book Series.
\n\nDesigned to cover fast-moving research fields in rapidly expanding areas, our Book Series feature a Topic structure allowing us to present the most relevant sub-disciplines. Book Series are headed by Series Editors, and a team of Topic Editors supported by international Editorial Board members. Topics are always open for submissions, with an Annual Volume published each calendar year.
\n\nAfter a robust peer-review process, accepted works are published quickly, thanks to Online First, ensuring research is made available to the scientific community without delay.
\n\nOur innovative Book Series format brings you:
\n\nIntechOpen Book Series will also publish a program of research-driven Thematic Edited Volumes that focus on specific areas and allow for a more in-depth overview of a particular subject.
\n\nIntechOpen Book Series will be launching regularly to offer our authors and editors exciting opportunities to publish their research Open Access. We will begin by relaunching some of our existing Book Series in this innovative book format, and will expand in 2022 into rapidly growing research fields that are driving and advancing society.
\n\nLaunching 2021
\n\nArtificial Intelligence, ISSN 2633-1403
\n\nVeterinary Medicine and Science, ISSN 2632-0517
\n\nBiochemistry, ISSN 2632-0983
\n\nBiomedical Engineering, ISSN 2631-5343
\n\nInfectious Diseases, ISSN 2631-6188
\n\nPhysiology (Coming Soon)
\n\nDentistry (Coming Soon)
\n\nWe invite you to explore our IntechOpen Book Series, find the right publishing program for you and reach your desired audience in record time.
\n\nNote: Edited in October 2021
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"4719",leadTitle:null,fullTitle:"Current Topics in Echinococcosis",title:"Current Topics in Echinococcosis",subtitle:null,reviewType:"peer-reviewed",abstract:"Echinococcosis remains an important cause of morbidity and mortality in certain areas of the world, tropical and non-tropical, particularly in rural settings. This book includes different topics with regard to the epidemiology, biology, clinical manifestations, treatment and prevention of the wide spectrum of diseases caused by the different species of Echinococcus involved in human and animal infection, with an aim to update the most significant research in many of them as well as to offer a multinational perspective on different aspects. The book has been organized into three major sections: (I) Epidemiology; (II) Biological and Clinical Aspects; and (III) Treatment and Prevention. Section I includes topics covering epidemiological studies in Colombia, Chile, Mexico and Tunisia, including molecular biology approaches to the study of parasite species. Section II includes topics covering the biology of some Echinococcus species affecting mainly animals, as also the human clinical manifestations in the central nervous system (CNS), genitourinary tract and other organic typical and atypical locations, as well as radiological manifestations of pulmonary disease. Section III includes topics on the usefulness of immunotherapy for antihelmintic treatment and intervention strategies.",isbn:null,printIsbn:"978-953-51-2159-6",pdfIsbn:"978-953-51-7251-2",doi:"10.5772/59732",price:119,priceEur:129,priceUsd:155,slug:"current-topics-in-echinococcosis",numberOfPages:222,isOpenForSubmission:!1,isInWos:1,isInBkci:!1,hash:"9bf40c20335433736665a335834c0ad8",bookSignature:"Alfonso J. Rodriguez-Morales",publishedDate:"September 2nd 2015",coverURL:"https://cdn.intechopen.com/books/images_new/4719.jpg",numberOfDownloads:18307,numberOfWosCitations:16,numberOfCrossrefCitations:8,numberOfCrossrefCitationsByBook:1,numberOfDimensionsCitations:18,numberOfDimensionsCitationsByBook:1,hasAltmetrics:1,numberOfTotalCitations:42,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"November 3rd 2014",dateEndSecondStepPublish:"November 24th 2014",dateEndThirdStepPublish:"February 28th 2015",dateEndFourthStepPublish:"May 29th 2015",dateEndFifthStepPublish:"June 28th 2015",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"8",totalChapterViews:"0",totalEditedBooks:"11",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1046",title:"Infectious Diseases",slug:"infectious-diseases"}],chapters:[{id:"48678",title:"Echinococcosis in Colombia — A Neglected Zoonosis?",doi:"10.5772/60731",slug:"echinococcosis-in-colombia-a-neglected-zoonosis-",totalDownloads:2446,totalCrossrefCites:3,totalDimensionsCites:3,hasAltmetrics:0,abstract:"Echinococcosis or hydatid disease is a near-cosmopolitan parasitic zoonosis caused by the larval stages of cestodes of the genus Echinococcus, whose spectrum of clinical manifestations can vary from asymptomatic infection to death, the liver being the most frequently affected organ. In the absence of an adequate treatment, case fatality rate of affected patients may reach 100%, so clinical suspicion should always be accompanied by a complete workup and a prompt treatment. Like other zoonotic parasitic diseases, echinococcosis is associated with low socioeconomic and cultural levels, especially affecting rural areas of developing countries, not only by the morbidity and mortality it produces, but also by the economic impact associated to health care costs and productivity losses. Despite this, in Colombia and in other South American countries, epidemiological studies of this disease are limited, so it is not known with certainty the incidence, the prevalence, and the burden of the disease. The objective of this chapter is to summarize and describe epidemiological and clinical updated aspects of the disease, focusing on evidences and published research articles on echinococcosis in Colombia, finally questioning if this cestode zoonotic disease has been largely neglected.",signatures:"Alfonso J. Rodriguez-Morales, Lauren Sofia Calvo-Betancourt,\nCamila Alarcón-Olave and Adrián Bolívar-Mejía",downloadPdfUrl:"/chapter/pdf-download/48678",previewPdfUrl:"/chapter/pdf-preview/48678",authors:[{id:"131400",title:"Prof.",name:"Alfonso J.",surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales"},{id:"159859",title:"Dr.",name:"Adrian",surname:"Bolivar-Mejia",slug:"adrian-bolivar-mejia",fullName:"Adrian Bolivar-Mejia"},{id:"176704",title:"Dr.",name:"Lauren Sofia",surname:"Calvo-Betancourt",slug:"lauren-sofia-calvo-betancourt",fullName:"Lauren Sofia Calvo-Betancourt"},{id:"176705",title:"Dr.",name:"Camila",surname:"Alarcón-Olave",slug:"camila-alarcon-olave",fullName:"Camila Alarcón-Olave"}],corrections:null},{id:"48773",title:"Echinococcosis in Mexico — A Story Worth Sharing",doi:"10.5772/60868",slug:"echinococcosis-in-mexico-a-story-worth-sharing",totalDownloads:1348,totalCrossrefCites:0,totalDimensionsCites:2,hasAltmetrics:0,abstract:"At the beginning of the XXI millennium, while working at a general hospital in Mexico City, a young lady arrived with a previous diagnosis of liver amebiasis given six years earlier. Different treatments in various clinical settings were provided. In the hospital, the first approach was an ultrasound study and unexpectedly an Echinococcus granulosus cyst was clearly identified. The patient received adequate treatment and accepted to participate as the index case in an epidemiological survey performed in her community. Inhabitants, dogs, cattle, pigs, and sheep were studied; cysts in humans, pigs, and sheep were searched by ultrasound and dogs by coproantigens, livestock, and dogs were negative for larval or adult stages respectively. The use of ultrasound allowed the detection of two cases (overall prevalence 0.95). DNA of the patient’s cyst recovered by surgery was purified, amplified, sequenced, and multiple alignments were performed and analyzed, identifying to Echinococcus ortleppi. Subsequently, in a population genetics study focused to evaluate the presence and genetic variability of the intestinal tapeworm in dogs and of cystic echinococcosis in livestock in central areas from Mexico, Echinococcus canadensis G7 was identified and was found only in pigs. Based on a genetic network analysis, the following deductions were made: 1) E. canadensis G7 in Mexico is very diverse and was probably introduced from abroad several times from different sources and from different countries; 2) G7 haplotypes grouped in the North American wildlife cluster are placed far from Mexican isolates, thus they might be ruled out as sources of introduction to Mexico; and 3) the species status for G7, formally named E. canadensis, is still controversial, because biologically different strains (G6 to G10) are currently unified, though ecological and genetic data appear to indicate otherwise.",signatures:"Ana Flisser, Pablo Maravilla, Pilar Mata-Miranda and Fernando\nMartinez-Hernandez",downloadPdfUrl:"/chapter/pdf-download/48773",previewPdfUrl:"/chapter/pdf-preview/48773",authors:[{id:"151598",title:"Dr.",name:"Ana",surname:"Flisser",slug:"ana-flisser",fullName:"Ana Flisser"},{id:"174556",title:"Dr.",name:"Pablo",surname:"Maravilla",slug:"pablo-maravilla",fullName:"Pablo Maravilla"},{id:"175057",title:"Dr.",name:"Fernando",surname:"Martinez-Hernandez",slug:"fernando-martinez-hernandez",fullName:"Fernando Martinez-Hernandez"},{id:"177232",title:"Dr.",name:"María del Pilar",surname:"Mata Miranda",slug:"maria-del-pilar-mata-miranda",fullName:"María del Pilar Mata Miranda"}],corrections:null},{id:"49047",title:"Molecular and Epidemiology Data on Cystic Echinococcosis in Tunisia",doi:"10.5772/60891",slug:"molecular-and-epidemiology-data-on-cystic-echinococcosis-in-tunisia",totalDownloads:1424,totalCrossrefCites:2,totalDimensionsCites:8,hasAltmetrics:0,abstract:"Cystic echinococcosis (CE) or hydatidosis is a widespread zoonose in the world. In Tunisia, despite the deployed prevention program, CE remains a serious public health problem. With a human surgical annual incidence averaging 12.6/100000 inhabitants, Tunisia is one of the most endemic areas amongst the Mediterranean countries. Three Echinococcus species have been described: E. granulosus sensu stricto (G1 and G3 genotypes), E. canadensis, and E. equinus. CE, which commonly starts during childhood and described as a young adult disease, may be observed at any age. The liver and the lungs are the most commonly involved organs but the cyst can occur almost anywhere in the body. In production animals, the prevalence of CE is ranged from 16.42% to 40.42% in sheep, 8.56% in cattle, 6% in dromedaries, 2.9% in goats, and 8.48% in donkeys. The elevated number of stray and semi-stray dogs and their frequent contamination by E. granulosus infected viscera is the major cause of the CE spread. A high prevalence of E. granulosus infection has been reported in Tunisian dogs ranging from 3.75% to 27.1%, depending on the regions. Thus, the sanitary education concerning hydatidosis should be reinforced and efforts should be made to implement a targeted educational program.",signatures:"Myriam Oudni-M’rad, Selim M’rad and Hamouda Babba",downloadPdfUrl:"/chapter/pdf-download/49047",previewPdfUrl:"/chapter/pdf-preview/49047",authors:[{id:"174835",title:"Dr.",name:"Myriam",surname:"Oudni-M'Rad",slug:"myriam-oudni-m'rad",fullName:"Myriam Oudni-M'Rad"},{id:"174925",title:"Dr.",name:"Selim",surname:"M'Rad",slug:"selim-m'rad",fullName:"Selim M'Rad"},{id:"174926",title:"Prof.",name:"Hamouda",surname:"Babba",slug:"hamouda-babba",fullName:"Hamouda Babba"}],corrections:null},{id:"48554",title:"Echinococcus shiquicus and Echinococcus felidis",doi:"10.5772/60819",slug:"echinococcus-shiquicus-and-echinococcus-felidis",totalDownloads:2290,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:1,abstract:"Currently, ten genotypes (G1-G10) of Echinococcus Sensu Lato have been explicitly identified on the basis of taxonomic criteria. These include morphometric keys, host specificity, geographical distribution, phylogenetic analysis and genome mapping. However, a few emergent species of genus Echinococcus have been indigenously confirmed in some autonomous regions of Tibet plateau and Africa where there is little known about their biological aspects and potential pathogenicity in intermediate and definitive hosts. This chapter is focused on the parasite history, life cycle, phenotypic aspects, epidemiology, zoonotic potential and phylogeny relationship of two enigmatic parasites namely: Echinococcus shiquicus and Echinococcus felidis. This aims to provide a better understanding of their taxonomic status, public health problems and biological features in the mentioned regions.",signatures:"Adel Spotin",downloadPdfUrl:"/chapter/pdf-download/48554",previewPdfUrl:"/chapter/pdf-preview/48554",authors:[{id:"174364",title:"Dr.",name:"Adel",surname:"Spotin",slug:"adel-spotin",fullName:"Adel Spotin"}],corrections:null},{id:"48631",title:"Brain Hydatid Cyst",doi:"10.5772/60820",slug:"brain-hydatid-cyst",totalDownloads:1648,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:1,abstract:"Brain echinococcosis is the most common brain parasitic infection in the world. It happens in a very rare location, representing 1% to 2% all cases with hydatid disease. It is more common by approximately 50–70% in pediatric population and young adultswith a male predominance. The definite hosts of echinococcus are various carnivores; man is an accidental host. The growth of hydatid cysts is usually slow and asymptomatic, and clinical manifestations are caused by compression of the involved organ. CT provides definitive results of diagnosis. It shows hydatid cyst as a spherical, well defined, thin walled, homogeneous and non-enhancing cystic lesion without peripheral oedema. Dowling technic is the most commonly done procedure designed to give birth to the intact cyst by irrigating saline between cyst wall-brain interfaces. Medical treatment can be indicated in multiple locations and in cases with peroperative rupture. Prognosis is often good, but same complications can occur after surgery and depend on the location, the size, the number of cysts and the technique used.",signatures:"Said Hilmani",downloadPdfUrl:"/chapter/pdf-download/48631",previewPdfUrl:"/chapter/pdf-preview/48631",authors:[{id:"174581",title:"Prof.",name:"Said",surname:"Hilmani",slug:"said-hilmani",fullName:"Said Hilmani"}],corrections:null},{id:"48601",title:"Genitourinary Hydatid Disease",doi:"10.5772/60904",slug:"genitourinary-hydatid-disease",totalDownloads:1550,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Genitourinary echinococcosis is an uncommon cyclo-zoonotic disease. It is caused by Echinococcus species. Kidneys are the common target organs in the genitourinary tract. Clinical presentation is usually non-specific. Pre-operative diagnosis requires a high index of suspicion. It should be considered in differential diagnosis of cystic mass of genitourinary tract, especially in endemic regions. Computed tomography, ultrasonography, and antibody testing aid in diagnosing and classifying the stage of the cyst. Although a number of operative techniques have been described, complete removal of germinal layer with daughter cysts without spillage of viable cyst contents with perioperative medical therapy provides an optimum chance of cure with minimal morbidity. Considering the benign nature of the disease, organ preservation is feasible in majority of the cases. The conventional open surgical treatment has evolved into minimally invasive laparoscopic, endoscopic, and even robotic techniques with concomitant improvement in postoperative and cosmetic outcome. Given the rarity of the disease, no randomized control trial comparing the treatment modalities for genitourinary hydatid exists. Moreover, long-term follow up in many cases is unavailable. Overall, the incidence of local and systemic recurrence is low.",signatures:"Santosh Kumar and Shivanshu Singh",downloadPdfUrl:"/chapter/pdf-download/48601",previewPdfUrl:"/chapter/pdf-preview/48601",authors:[{id:"174359",title:"Dr.",name:"Santosh",surname:"Kumar",slug:"santosh-kumar",fullName:"Santosh Kumar"},{id:"174895",title:"Dr.",name:"Shivanshu",surname:"Singh",slug:"shivanshu-singh",fullName:"Shivanshu Singh"}],corrections:null},{id:"48872",title:"Echinococcosis — Rare Locations and Uncommon Clinical Manifestations",doi:"10.5772/61126",slug:"echinococcosis-rare-locations-and-uncommon-clinical-manifestations",totalDownloads:1446,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:1,abstract:"Echinococcosis is a zoonotic infection caused by tiny tapeworms of the genus Echinocococcus. Cystic Echinococcosis, also known as hydatid disease, is caused by Echinococcus granulosus and rarely by Echinococcus multilocularis.",signatures:"Antonio Di Cataldo, Giuseppe Petrillo, Claudia Trombatore, Stefano\nPalmucci, Antonella Agodi, Martina Barchitta, Annalisa Quattrocchi,\nNunzio Crimi, Silvia Fichera, Stefano Puleo, Amy Giarrizzo, Martina\nCalabrini, Rosalia Latino and Rosanna Portale",downloadPdfUrl:"/chapter/pdf-download/48872",previewPdfUrl:"/chapter/pdf-preview/48872",authors:[{id:"90868",title:"Prof.",name:"Antonio",surname:"Di Cataldo",slug:"antonio-di-cataldo",fullName:"Antonio Di Cataldo"}],corrections:null},{id:"48613",title:"Radiological Characteristics of Pulmonary Hydatid Cysts",doi:"10.5772/60884",slug:"radiological-characteristics-of-pulmonary-hydatid-cysts",totalDownloads:3358,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Hydatid disease is a parasitic infection caused by Echinococcus granulosus (EG), characterized by cystic lesions in the liver, lungs, and rarely in other parts of the body. Lungs and liver are the most frequent sites involved. Simultaneous lung and liver cysts are observed in less than 10% of the cases. Hydatid cysts are found more frequently in the lungs of children and adolescents than in their liver, while most cysts in adults are hepatic and relatively few are in the lungs. The hydatid serology results are often negative in patients with isolated pulmonary hydatidosis, and hence may not be helpful in problematic cases. Radiologic approach to the intact, complicated, or ruptured pulmonary hydatid cysts includes a CT scan following the chest radiograph. Thoracic CT may be supplemented with magnetic resonance (MR) imaging and occasionally with ultrasound (US) in clarifying a pleural-based hydatid cyst as extrapleural, pleural, or parenchymal.",signatures:"Dilek Emlik, Kemal Ödev, Necdet Poyraz and Hasan Emin Kaya",downloadPdfUrl:"/chapter/pdf-download/48613",previewPdfUrl:"/chapter/pdf-preview/48613",authors:[{id:"174536",title:"Associate Prof.",name:"Ganime Dilek",surname:"Emlik",slug:"ganime-dilek-emlik",fullName:"Ganime Dilek Emlik"}],corrections:null},{id:"48811",title:"Immunotherapy Can Enhance Anthelmintic Efficacy in Alveolar Echinococcosis",doi:"10.5772/60763",slug:"immunotherapy-can-enhance-anthelmintic-efficacy-in-alveolar-echinococcosis",totalDownloads:1343,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The immune response of the intermediate host with alveolar echinococcosis was investigated on mice intraperitoneally infected with Echinococcus multilocularis protoscoleces. The study was focused on cell-mediated immune response (dependent on interactions of T lymphocytes and macrophages), which is considered protective in alveolar echinococcosis. The immune response to E. multilocularis is regulated by Th1/Th2 cytokines produced by the CD4+ T lymphocyte subpopulation. Metacestode has been known for its ability to modify immune functions and suppress effective specific cell response to ensure its survival in host organism. The influence of immunomodulatory substances – muramyltripeptide (L-MTP-PE), glucan (GI), glucan with zinc (GIZn), and transfer factor (TF) – applied alone or combined with anthelmintic albendazole (ABZ) on regulative and effector components of immunity were tested and at the same time, antiparasitic efficacy of immunomodulators was evaluated.",signatures:"Emília Dvorožňáková",downloadPdfUrl:"/chapter/pdf-download/48811",previewPdfUrl:"/chapter/pdf-preview/48811",authors:[{id:"174391",title:"Dr.",name:"Emilia",surname:"Dvoroznakova",slug:"emilia-dvoroznakova",fullName:"Emilia Dvoroznakova"}],corrections:null},{id:"48743",title:"Hydatidosis and Intervention Strategies",doi:"10.5772/60838",slug:"hydatidosis-and-intervention-strategies",totalDownloads:1456,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Human echinococcosis is a zoonotic infection caused by larval forms (metacestodes) of tapeworms of the genus Echinococcus. Among the recognised species, Echinococcus granulosus and E. multilocularis are of considerable medical importance, causing cystic and alveolar echinococcosis (AE and CE), respectively. The factors of immunology, host-genetic inherits, and Echinococcus genetic-diversity and adaption clearly influence infectious establishment and disease progression. However, subtle mechanisms between host and parasite interactions/relationships are still open to study for answers. Despite the global burden, echinococcosis remains a neglected zoonosis. The importance of environmental factors influencing the transmission intensity and distribution of Echinococcus species is increasingly being recognised. The intervention strategies for this public health threat have integrated host immune-genetic research, parasite adaptation, and genetic diversity analysis, as well as the transmission dynamic investigations; the limitations of current control programmes are clearly presented in this study that hampers the elimination of Echinococcus species worldwide. Continuous efforts by multidiscipline researches are needed.",signatures:"YuRong Yang",downloadPdfUrl:"/chapter/pdf-download/48743",previewPdfUrl:"/chapter/pdf-preview/48743",authors:[{id:"174906",title:"Dr.",name:"YuRong",surname:"Yang",slug:"yurong-yang",fullName:"YuRong Yang"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"825",title:"Current Topics in Tropical Medicine",subtitle:null,isOpenForSubmission:!1,hash:"ef65e8eb7a2ada65f2bc939aa73009e3",slug:"current-topics-in-tropical-medicine",bookSignature:"Alfonso J. Rodriguez-Morales",coverURL:"https://cdn.intechopen.com/books/images_new/825.jpg",editedByType:"Edited by",editors:[{id:"131400",title:"Prof.",name:"Alfonso J.",surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. 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Next-generation textiles can also be considered an important part of technical textiles, being used for different purposes such as chemical and biohazard protection. They present an important aspect from an economic point of view and the necessity for their production has been increasing; for example, a huge necessity for smart medical textiles comes from the increase of the elderly population in developed countries. In the last few decades, the rapid development of command cotton fabrics also occurred. This affects all textile sectors, for example, biodegradable fibers for implantations, three-dimension spacer fabrics, and reduction of bacterial growth by using silver ion-based textiles finishing. In this and other ways, the fields concerning the next-generation textiles have been growing rapidly and are becoming a more complex area to understand.
",isbn:"978-1-80355-883-7",printIsbn:"978-1-80355-882-0",pdfIsbn:"978-1-80355-884-4",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,hash:"093f9e26bb829b8d414d13626aea1086",bookSignature:"Dr. Hassan Ibrahim",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11124.jpg",keywords:"Next-Generation Textile, Intelligent Textile, Smart Textile, Technical Textile, Next-Generation Material, Medical Textile, Sustainable Textile, Nanofiber, Fabric, Smart Material, Biodegradable Fiber, Technological Innovation",numberOfDownloads:27,numberOfWosCitations:0,numberOfCrossrefCitations:0,numberOfDimensionsCitations:0,numberOfTotalCitations:0,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"November 5th 2021",dateEndSecondStepPublish:"February 24th 2022",dateEndThirdStepPublish:"April 25th 2022",dateEndFourthStepPublish:"July 14th 2022",dateEndFifthStepPublish:"September 12th 2022",remainingDaysToSecondStep:"3 months",secondStepPassed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"Dr. Hassan Ibrahim was the Egyptian National Representative of the Chemistry and Human Health Division Committee (VII) at the International Union of Pure and Applied Chemistry (IUPAC) in 2018-2019 and is currently a member of several national committees of pure and applied chemistry. 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He supervised 8 PhD and M.Sc. thesis, and participated in 14 national and international projects dealing with organic and environmental chemistry, hazardous wastes, medical textiles, nanotechnology, and electrospun nanofibers formation. He has expertise in applied chemistry and technology of organic chemistry, especially in carbohydrates, polymers, pollution prevention, preparation, and applications of nanoparticles (polymer chemistry, chemistry of chitosan, chitosan modification, nanoparticles preparation, and electrospinning technique). He built this model after years of research and teaching at university and research centers. He was the Egyptian National Representative of the Chemistry and Human Health Division Committee (VII) at the International Union of Pure and Applied Chemistry (IUPAC) in 2018-2019, and is currently a member of several national committees of pure and applied chemistry. 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In developed countries, the costs associated with dialysis treatment and transplantation consume 2 to 3% of the health budget. On the other hand, in middle and low-income countries the accessibility to kidney function replacement treatments is low [1].
Chronic kidney disease (CKD) is considered a public health problem and has a significant weight in the context of chronic diseases. This disease affects around 850 million people worldwide, with one in ten adults having chronic kidney disease [2].
All stages of the disease - 1 to 5 -, are associated with increased risk of cardiovascular morbidity, premature mortality and quality of life decrease [3].
Considering the weight of hypertension, cardiovascular disease and diabetes mellitus in the increase of CKD, it is crucial to be concerned with its management.
There is a complex association between CKD and hypertension due to a cause-effect relationship, in which both hypertension and CKD have a risk factor sharing relationship, being that one may be the cause or consequence of the other. Every year the number of people diagnosed with CKD due to hypertension increases by 10%.
The literature states that 5% of CKD are due to hypertension. It is highlighted that hypertension is more common in glomerular diseases, but the incidence of this clinical condition differs according to the histological characteristics of the disease. Membranoproliferative glomerulonephritis and segmental and focal glomerulosclerosis forms have a higher incidence of hypertension than membranous forms and IgA glomerulopathy. Table 1 shows the prevalence of hypertension in different chronic renal diseases [4].
Chronic kidney disease | % of hypertension patients |
---|---|
Glomerular diseases Segmental and focal glomerulosclerosis Membranoproliferative glomerulonephritis Diabetic nephropathy Membranous nephropathy Mesangial proliferative glomerulonephritis IgA nephropathy Minimal change disease | 75–80 65–70 65–70 40–50 35–40 30 20–30 |
Polycystic kidney disease | 60 |
Chronic interstitial nephritis | 35 |
Hypertension prevalence in CKD patients.
The evidence supports that the prevalence of hypertension increases as kidney function deteriorates in CRD, with a progressive decrease in the glomerular filtration rate [5].
Several studies have shown that hypertension is an independent risk factor for end-stage renal disease (ESRD), contributing to the disease itself and its progression [6, 7].
Cardiovascular disease is the leading cause of death in CKD, which in turn, increases the risk of long-term cardiovascular events [8].
When compared to the general population, the prevalence of hypertension is higher in people with CKD, constituting the factor with the greatest impact on the progression and outcome of kidney disease [9].
It is not yet known the exact mechanism that causes hypertension in CKD, nor has been isolated any factor responsible for its establishment. It is theorized that there are several mechanisms that, acting together, contribute to increased blood pressure, such as the progressive loss of sodium excretion with the consequent volume overload, the excessive activity of the renin-angiotensin system, the disproportionate increase in sympathetic activity, secondary hyperparathyroidism, the reduction of nitric oxide synthesis and the high endothelin levels, among others [10, 11].
Observational studies report an increased risk of development and rapid progression of CKD in cases of uncontrolled blood pressure [12].
Failure to treat hypertension is associated with harmful effects such as left ventricular hypertrophy, dilated cardiomyopathy and accelerated deterioration of renal function, among other causes [10].
According to Kidney Disease Improving Global Outcomes (KDIGO), international organizations (such as National Kidney Foundation Kidney Disease Outcomes Quality Initiative - NKF KDODQI; Eighth Joint National Committee published - JNC 8) committed to the prevention and treatment of hypertension recommend non-pharmacological measures along with pharmacological measures in the prevention and treatment of this disease [13, 14].
According to these organizations, health professionals are responsible for early detection of the disease and monitoring of risk factors.
The disease can progress slowly due to the gradual loss of the nephrons, and in its initial stages it goes unnoticed, only being identified when symptoms appear.
The purpose of screening and monitoring the disease in the early stages is to delay its progression to ESRD, a condition that leads to the need for renal replacement therapy.
Only a minority of patients with hypertension have blood pressure within the accepted target values (systolic blood pressure less than 140 mmHg, diastolic blood pressure less than 90 mmHg). The main causes for the lack of blood pressure control are related to low knowledge of the problem and lack of screening for hypertension in the population [15].
In the context of non-pharmacological measures, European Society of Cardiology makes clear the urgent need to promote preventive actions, mentioning that blood pressure measurement is a simple, non-invasive and low-cost technique, especially if considering the costs of treating hypertension and associated complications.
Regarding hypertension and kidney disease, there is no consensus among the authors about what the reference values should be. This is an issue that remains in debate despite recent recommendations and the publication of the clinical trials SPRINT, ACCORD, among others [16, 17].
The European Society of Hypertension and the European Society of Cardiology (ESH/ESC) recommend target blood pressure values below 140/90 mmHg for blood pressure measurements in a clinical setting. However, in the presence of proteinuria, these values drop to 130/80 mmHg as a reference. Similar recommendations are indicated by the JNC-8, suggesting target blood pressure values below 140/90 mmHg for the general population, disregarding the recommendations of SPRINT study, which suggests blood pressure values below 130/80 mmHg for patients at increased risk of cardiovascular events, including patients with CKD [18].
Target blood pressure values have changed over time. The literature shows that the target blood pressure value acceptable for patients with CKD is 130/80 mmHg [19]. The latest guidelines of the European Society of Hypertension and the European Society of Cardiology published in 2018 recommend a target SBP (Systolic Blood Pressure) value of 130–139 mmHg and DBP (Diastolic Blood Pressure) of 70–79 mmHg for patients with CKD. But there is not a unanimous view among scientific community on this issue [20, 21].
Vital for the success of the blood pressure prevention and control programs is the participation of the patient/family.
Health care, as integrating element of praxis, which takes place during the course of the chronic disease, calls for the participation of all stakeholders in the care process and for the investment in patients’ education, enabling them to understand their health needs and become co-responsible for their health and well-being [22].
Everybody should to be part of an active citizenship stance based on education and training. Care must focus on the needs of the patient, it is important to know their level of mastery in response to the needs considered significant at any stage of the disease pathway [23].
Blood pressure self-monitoring has been proposed as a strategy to improve hypertension control. Although the results of previous clinical trials on blood pressure measurement in the adjustment of hypertensive therapy and in the control of hypertension are inconsistent, the results of TASMINH4 demonstrated that 90% of eligible participants revealed that they wanted to take an active role in self-monitoring of blood pressure [24].
However, the importance of new studies in this area is highlighted, mainly studies involving risk groups, including patients with CKD in the advanced stage of the disease [25].
Hypertension is common in CKD patients, with a prevalence of around 60% to 90%, depending on the stage and cause of the disease, and is responsible for high cardiovascular morbidity and mortality. In this context, blood pressure control is a key measure [10].
HBPM is easier than ambulatory blood pressure measurement and, therefore, can be an important tool for blood pressure control in combination with other measures.
In this regard, Sanghavi, & Vassalotti emphasize that measuring blood pressure at home is a mean of reducing the burden of medication in individuals with “white coat hypertension”, that is defined as the increase in blood pressure in the clinical context and maintenance of normal values at home. And, therefore, a means of improving the therapeutic compliance of hypertensive patients [26].
The authors also add that HBPM offers the patient a means to monitor the effectiveness of the medication and acts as a positive reinforcement, as shown by a study carried out in Spain. Of the 250 participants, 92% of the individuals in the experimental group (home blood pressure measurement) adhered to the antihypertensive regime, against 74% in the control group.
They concluded that HBPM is simple and not expensive. Besides, it offers more information to the practitioner, allowing more informed clinical decisions. It also promotes the involvement of the patient and the commitment of the health team, including nurses.
The evidence that shows the benefits of HBPM compared to measuring blood pressure in the clinical setting. Namely in improving blood pressure control, in reducing “white coat hypertension” events and in cardiovascular risk prediction [27, 28, 29].
The diagnosis of “white coat hypertension” is important because one of the consequences of this situation is overtreatment [30].
CKD patients with “white coat hypertension” have a lower cumulative risk of progressing to ESRD, so home blood pressure monitoring is essential. On the other side, renal patients have a high prevalence of masked hypertension, defined as normal blood pressure values in the clinical setting and high blood pressure values at home or ambulatory. This situation puts them at risk of organ damage, cardiovascular events and tends to evolve to ESRD [31].
HBPM allows a complementary assessment of daytime blood pressure variation, commonly seen in chronic kidney patients [32, 33].
Self-measurement of blood pressure at home is therefore an alternative for measuring blood pressure. Besides providing a more accurate assessment of blood pressure, it offers the possibility of having regular measurements in conditions closer to the patients’ daily lives [34].
It is recognized by the scientific community that the measurement of blood pressure in the clinical context does not accurately reflect the blood pressure of each individual (due to changes in circadian rhythm and in the environment). It is thus necessary to create alternative methods whose main goal is to enable a closer assessment of the patient’s values, because it takes place in a natural context, in the patient’s natural environment [35].
Therefore, the self-monitoring of blood pressure at home becomes a tool to be incorporated into the self-care of CKD patients, through which the person has control over the process. This action makes the patient co-responsible for their health. This is a simple and important measure in preventing progression to ESRD, but it is nevertheless a complement to blood pressure measurement in the clinical context [36].
The negative individual, social, and economic consequences of not controlling blood pressure are evident. But these effects can be positive when enhanced by the self-management of hypertension.
The main negative effects resulting from the lack of blood pressure control in CKD patients call for the development of self-care interventions that result in behavior modification and optimization of hypertension control.
This issue is evident in the study by Humpherys et al., which, through a multifaceted intervention approach, optimized blood pressure values in proteinuric CKD patients and unproteinuric CKD patients. For that, the authors run 4 projects, which occurred in different practices, established chronologically in different periods of time. The percentage of patients with self-care behaviors for blood pressure management within the recommended target values increased from 34% to 74% in project 1, from 60% to 83% in project 2, from 68% to 71% in project 3 and 63% to 76% in project 4. Both groups (proteinuric and unproteinuric CKD patients) were able to reach the recommended target blood pressure values. The group of unproteinuric patients achieved blood pressure values below 140/90 mmHg and the group of proteinuric patients reached values of blood pressure below 130/80 mmHg. In this context, the authors concluded that this type of intervention proves to be an asset in reducing long-term complications resulting from suboptimization of blood pressure control [22].
The analysis of the systematic literature review carried out by Gallagher, et al. shows us the positive effects of educational interventions in reducing high blood pressure. The benefits of health education interventions in lowering blood pressure in chronic kidney patients were confirmed. As well as their potential in reducing cardiovascular events and delaying the progression of the disease [37].
Given that nurses have a pivotal role in promoting self-care behaviors in all aspects of care, including (1) problem identification, (2) diagnosis, (3) intervention, (4) evaluation and (5) follow-up, it is essential to highlight the interventions developed in the context of high blood pressure control in chronic kidney patients.
According to the literature, the possible causes of blood pressure control in this target group are associated with a reduction in self-care behaviors in relation to the consumption of salt, the practice of physical exercise and the adherence to medication. The overlook of these behaviors leads to hypertension. In this context, non-pharmacological interventions are relevant, along with pharmacological measures [38].
Health education, as a field for knowledge production, assumes a privileged relationship with active citizenship, providing patient/family with the possibility of making informed decisions and acting in collaboration with the health team.
Assuming the empowerment speech as a key element of the care action, which is shaped at the border between the biomedical model and the model of care centred on the patient, Orem’s theory of self-care fits in this context. Especially when it is intended to establish partnerships and promote self-care behaviors in the prevention and control of hypertension in patients with CKD through an educational intervention.
According to Orem, the individual is an active subject, but in a situation of illness, his capacity for self-care can be reduced due to his inefficiency in relation to the condition that affects him [39].
In 2013, the World Health Organization (WHO) defined self-care as the ability of individuals, families and the community to promote health, prevent disease and stay healthy. The partnership with healthcare professionals to deal with the disease and disabilities arises when individuals are unable to meet some or all of the needs for self-care, due to a lack of knowledge, disability or perception of their diminished health status.
Nurses act as a resource for the patient, developing helping methods in order to overcome or compensate health-related limitations, leading the patient to undertake actions to regulate their own functioning and development. The intervention is carried out according to a diagnostic and intervention process. It starts with needs assessment, identification of motivation to learn and, in partnership with the patient and/or family, establishment of the goals to be achieved. In this process the nurse can direct, guide, provide support and teach [39].
CKD patients need to undertake a range of complex activities, such as monitoring blood pressure, blood glucose, introducing changes in diet, adhering to therapy, avoiding nephrotoxic substances and practicing physical exercise [40].
It is internationally recognized that disease self-management is now an essential aspect of the health system. The implementation of a disease self-management plan based on negotiated complementary actions, allows the process participants to rediscover the conditions (knowledge and skills) to satisfy their needs. With the aging of population, families assume an increasing importance in the daily management of the disease. Therefore, families and patients are the clients of health professionals and the expression of their interests must be taken into account [41].
There are many difficulties for active participation of individuals in the management of their disease due to lack of knowledge and skills to deal with the disease. Therefore, between unawareness and fears, people’s behavior can take two directions: control or ignore the problem. In either cases, nurses have a predominant support role in making people aware of their potential, leading them to develop and put that potential at the service of the disease.
Health education is a strategy to be followed, as it constitutes a teaching, instruction and training tool in order to guide the patient and their families to face a new situation in the management and prevention of the disease.
It is true that CKD patients have the same characteristics as the general population in terms of self-care behaviors in controlling blood pressure, following a healthy diet and regular physical exercise. However, it is no less true that CKD disease, due to its complexity and need for intervention in all of the stages, requires specific intervention and monitoring actions along the path of the disease.
As CKD is an asymptomatic disease, especially in the early stages, it means that patients with CKD, because they are unaware of their situation, do not seek information. It is also a fact that the low perception of susceptibility is associated with low levels of literacy and, consequently, with a reduced perception of the risk of developing the disease [40].
This discouraging picture highlights important gaps regarding the patient’s monitoring plan. In this context, innovative and complementary practices are needed to implement an individualized monitoring program based on the patient’s real problems, both in hospitals and in primary health care. As a reference, we identify health education projects developed in specialized hospital consultations, or even in the wards, based on information, instruction and training techniques aimed at this population.
The question that arises is: what directions can be pursued to achieve these goals?
Firstly, it is essential to identify and accurately assess self-care behaviors, regarding blood pressure monitoring at home and levels of activation in disease management in its various stages. Secondly, the implementation of an intervention that promotes knowledge, skills and patient activation in the disease management. That is, providing the means to enable patients to make informed decisions, make a self-monitoring and self-assessment of their condition and implement strategies to solve some problems that arise [42].
Indeed, in the context of CKD research, self-management interventions are on the top of the agenda when it comes to preventing disease progression [43]. For example, Havas et al. indicates that chronic kidney patients reported the need to learn how self-manage their disease and to integrate self-management behaviors into their daily lives [44].
In this context, the education process is a fundamental tool. For it to be successful it is important to take into account the motivation, the literacy level, the patient activation in disease management and the patient/health professional relationship [45].
Activation is an interactive process and consists of the patient’s ability to actively participate in disease management, to assume an active behavior in favor of a passive attitude. Several factors take action in this process, such as the patient’s motivation, beliefs, knowledge and abilities/skills to perform [46].
Activated patients have higher scores for participation in disease self-management, namely blood pressure monitoring, healthy eating habits, physical exercise, smoking cessation, etc., when compared to those who are not [47].
Activation exists in a continuum in which the patient moves between four levels, depending on state of health, self-confidence, motivation to get involved and circumstances of life.
The four levels are:
Along with the concept of patient activation, the concept of perceived efficacy gains relevance in the disease self-management. To the previous ones, demographic characteristics (age, gender, education) and clinical characteristics (cognitive and physical capacity) are added.
Perceived self-efficacy refers to the person’s perception of their own ability to perform a certain activity in order to achieve a goal or result. According to Bandura, it is important for people to believe that they are able to successfully develop a certain action, because that will be the guarantee of getting involved and adopting goals for that purpose [49].
Bandura also defines how much effort a person will need and how long it will last when faced with difficulties and negative experiences. There is a tendency to avoid situations that may exceed the limit of the person’s capabilities and to deal with those that the person thinks are solvable. The person tends to distance from situations with high levels of demand, offering the most varied justifications [50].
In this way, different scores for perception of self-efficacy can increase or decrease the motivation for action, with higher self-efficacy scores corresponding to better health. Previous research has shown this relationship, in addition to showing that high self-efficacy was associated with positive changes in health behaviors [49].
Several studies in nephrology field have found an association between high levels of perceived self-efficacy and health gains in groups of hemodialysis patients, regarding weight control improvement between dialysis sessions, reducing hospitalizations, amputations and improving quality of life [51].
Taking into account the international scenario, hypertension represents a burden for global disease context. Thus, standardized blood pressure measurement is essential for diagnosis and blood pressure management [36].
Lopez-vargas et al. showed that patients with CKD in the most advanced stages have low levels of knowledge about the associated risk factors, including hypertension and its management. The authors found that 54% of the patients received information on blood pressure monitoring, adherence to therapy and food preparation. They also identified that nurses had the main role of educators in 73% of the necessary studies. The results indicated that of the 54% of the patients involved in disease self-management, 31% had their blood pressure controlled [52].
The interventions that most contributed to the effectiveness of the process were: teaching practical skills, workshops, follow-up patient on a regular basis and negotiating goals to achieve.
Patients involved in blood pressure monitoring at home learn to understand the connection between measuring and controlling blood pressure and more easily adhere to strategies that contribute to controlling blood pressure, specifically diet, exercise and adherence to therapy. This attitude towards the disease shows improvements in health status [53].
For Wanchai & Armer nurses can help the patient to improve their self-care skills [54]. The question is: how to do it?
Returning to Orem’s theory, the authors mention that there are three classifications of nursing systems to meet the self-care requisites of the patient: wholly compensatory system, partially compensatory system and the supportive-educative system. Regarding the first system, nurses need to completely replace the individual due to the inability to self-care. In the second system, a patient can meet some self-care requisites but needs a nurse to help meet other needs. In the supportive-educative system, a patient can meet self-care requisites but needs assistance with decision making, behavior control, or knowledge acquisition skills, so nurses teach, train and support the patient for self-care. Often the patient is unable to perform his activities because he does not have the necessary knowledge to perform them. According to Orem, in some situations, the patient needs the nurse’s guidance to carry out the self-care action and in other situations he needs to learn the techniques to be able to perform them.
The authors mention other methods of training the patient for self-care, promoted by nurses, such as coaching, stimulating the patient’s participation and establishing of therapeutic relationship.
The authors add the motivational interview as a strategy to motivate the patient to change specific behaviors. They also report that review studies have shown the effectiveness of this method in changing behaviors for healthy lifestyles. Other authors have stated that this type of approach is useful in situations where the patient is less motivated to assume self-care or in situations where the patient not yet prepared to take charge of his illness condition.
In the context of health education, giving educational materials can help the patient in the learning process. However, it is necessary to pay attention to the patient’s abilities in terms of reading and comprehension to avoid bad decisions about self-care. The demonstration and training blood pressure measurement in different methods involving the technique of blood pressure measurement at home should be promoted. Additional resources such as videos, access to websites dedicated to this subject or leaflets demonstrating the technique, may be useful in demonstrating blood pressure monitoring at home.
Nurses play an important role in this process, helping the patients to select and understand the best method for themselves [55].
Nurses should inform the patient about the recommended schedule for blood pressure monitoring at home. According to the European Hypertension Society Working Group, blood pressure should be taken twice in the morning and twice in the afternoon [56].
In some experts’ opinion, blood pressure self-monitoring over a long period may allow a more accurate assessment of blood pressure stability and increase the patient’s commitment to treatment.
Nurses should discuss with patients the importance of blood pressure self-management. Therefore, an important element in this whole process is the communication established between the health professional and the patient. Feedback should be maintained even when the professional is not on duty. The patient should be able to communicate with the healthcare professional via telephone, fax and e-mail. There are also other ways of data communication, namely through stored data in devices, mobile phone applications (smartphone applications) and internet.
Nurses can help the patient to obtain health gains through adequate training in blood pressure measuring methodology and interpreting the values obtained in blood pressure monitoring at home.
To this purpose, nurses should explain and demonstrate the technique to the patient and inform about the recommended devices [57]. The Table 2 shows the Society of Cardiology and the European Society of Hypertension recommendations regarding blood pressure measurement at home.
Environment | Comfortable environment temperature Quiet and noiseless environment |
---|---|
Patient | Training in blood pressure measurement technique is required
|
Blood pressure measurement devices |
|
Recommendations for HBPM.
Regarding device selection, literature indicates that the recommended devices for HBPM are the automatic oscillometric arm devices. This kind of equipment is more user-friendly and requires less skills when compared to manual devices.
Electronic arm devices for BP measurement, especially those that allow the storage, transmission or printing measuring data, should be preferred for HBPM. It is also crucial that patients make sure that the devices they acquire have been validated according to recommended criteria. The European Society for Hypertension Working Group on Blood Pressure Monitoring has developed a protocol applicable to most BP measuring devices available on the market. The European Society of Hypertension supported the creation of a website where updated lists of validated BP measurement devices are published (www.dableeducational). The British Hypertension Society (www.bhsoc.org) also publishes information on device validation.
In Herber, et al., it is essential that the patient and family have coping strategies to deal with the disease and complications. The authors highlight the role of regular home visits in establishing a therapeutic relationship. In these visits, nurses can support and teach the patient and family to manage the therapeutic regimen, increase levels of knowledge about the disease and self-care behaviors, as well as guide the resources available in the community [58].
For Coates et al., the management of the disease is challenging, both for the patient and his relatives, as well as for health professionals, as it requires a change in the philosophy of care. The paradigm change demands the active involvement of the patient in decisions and problem solving. In this context, new strategies are required to make the patient responsible for the management of his health [59].
Negotiation is, thus, an important strategy to prevent the patient from adopting a passive attitude and, at the same time, to equip the patient with the necessary skills and abilities for disease management [60].
Advice and support in changing daily routines are essential for the control of HTA [61].
Blood pressure self-monitoring makes patients more aware of their pressure values and leads them to commit themselves more actively in their therapeutic plan.
In summary, self-care is an essential component for chronic disease management and, in the case of CKD, is certainly a sine qua non condition. The evolutionary path of CKD brings with it a growing number of daily self-care activities for the individual, such as deciding what to do, undertaking self-care activities related to disease monitoring and putting a strong increase in the investment of healthy behaviors, including blood pressure control, diet and exercise, among others.
The health gains for the patient consist of increased quality of life, empowerment, success in lifestyle changes due to active role and involvement in disease management. The change in perception of hypertension can encourage the patient to comply with therapy and make the necessary lifestyle changes [62].
The main objective of HBPM is to prevent and delay morbidity, mortality and organ damage. To achieve this goal, it is essential to implement pharmacological and non-pharmacological measures, including: regular blood pressure measuring throughout life at home. This self-care behavior results in gains for the patient as it has been shown in CKD patients. Adequate blood pressure control reduces the rate of decline in kidney function and cardiovascular morbidity and. In this context, HBPM is important for the effective management of hypertension in this group with compromised kidney function [27, 63].
Nurses play an important role in patient empowerment by accompanying, teaching, training and informing about hypertension and the additional measures needed to achieve the expected result: blood pressure control and quality of life. The establishment and maintenance of a model of care based on cooperation between health professionals and the patient is the key to success.
The authors declare no conflict of interest.
Polymer plasticization is a complex process with many uncertain variables, which involves phase transfer and viscoelastic behavior. The nonlinear effect of polymer plasticization is a multidisciplinary engineering science problem that includes heat transfer, rheology, and flow dynamics among others. The thermal homogeneity and stability of polymer melts in this plasticization process is the key to determine the quality of products, especially for biodegradable nanocomposites or microcellular foam materials.
\nIn polymer processing, plasticization screw is an added unit operation that facilitates melting and homogenization of an initially heterogeneous physical system [1, 2]. In general, the temperature distribution is not uniform in the process of plasticization; this is due to significant friction heating and the low thermal conductivity of polymers. It is very important to optimize the structural parameters and working characteristics of the screw in order to enhance plasticization of polymers. The effect of barrel configurations and screw designs on heat and mass transfer has been investigated in the past and proved unquestionably important attributes for determining temperature uniformity and mixing effectiveness in extrusion and injection molding processes [3, 4, 5, 6, 7, 8]. Different from conventional screw, the new types of screw can be roughly divided into four categories: distribution screws, barrier screws, separator screws, and channel screws with variable sections. These reconfigured screws are stated to be better than a standard one. For example, Kelly et al. [6] developed a barrier-flighted screw with Maddock mixer to achieve good melting performance and low temperature and pressure fluctuations. Spalding [9] introduced a distributive melt-mixing type screw equipped with an Eagle mixer in injection molding process and obtained better melting capacity and higher mixing than a conventional screw. Shimbo et al. [10] disclosed a mixture system by combining Pin and Dulmage type screws and also reported their beneficial effect in kneading, homogenization, and ensuring stability of gas/polymer solution. Zitzenbacher et al. [11, 12] indicated that the shearing sections like axial and spiral Maddock elements and Z-elements are often used to improve the melt homogeneity by enhancing dispersive mixing. Rydzkowski [13] developed an autothermal screw-disc extruder to induce autothermal effect. Rauwendaal [4] noted a CRD mixing screw with wedge-shaped barrier region to generate elongational flow. In this way, the mixing ability improves under the condition of lower power consumption and viscous dissipation than shear flow. Also, the melt temperatures and pressure fluctuation reduce in the flow channel. Based on the elongational flow and volume transportation, Qu et al. [14, 15] proposed a novel vane plasticization system in place of screw one to create extensional stress. Their results showed that the plasticizing capacity improved with the decrease of power consumption in the vane extruder. Diekmann [16] analyzed the direct-drive single-screw extruders without gearing and results indicated that plasticization capacity increased in the direct-drive system. Besides, Jiang [17] introduced ultrasonic plasticizing in the extruder to achieve energy saving. And Qu et al. [18] introduced a vibrational force field in the screw plasticization system. Their results showed that mixing performance improved and extrusion pressure reduced.
\nThese studies may focus on mixing and rheology. However, heat transfer also plays a significant role in plasticizing. In the past, researchers paid little attention to understand heat transfer in viscous fluid. Understanding the mass and heat transfer processes in a plasticization system as a function of screw configurations is essential to further develop a more effective screw design to overcome some of the existing challenges. The properties of composites in the plasticization process also depend on the control of the velocity, temperature, shear, and pressure fields. Therefore, it is worth investigating the synergetic relationship, if any, between various physical fields in order to maximize the efficiency of the plasticization effect.
\nMixing a high-viscosity or high-molecular weight polymer melt leads to shear-induced overheating due to the large torque induced, required to unleash the polymer chain entanglements. The challenge in this case is to fabricate a screw configuration that facilitates polymer chain mobility in melt phase without inducing high shear and by facilitating effective transfer of the excess local heat out of the bulk of the polymer melt. Otherwise, the local overheating effect essentially results in unwanted heat loss and poor melt quality, subsequently, the polymer chains break down and thermosensitive polymers such as biopolymers may even be degraded.
\nIn order to overcome the challenges of an inadequate control of flow-thermal management for multicomponent melt, we explore the synergistic relationship and interaction mechanism between various physical fields for non-Newtonian viscous liquids such as polymer melts, with special emphasis on higher molecular weight thermoplastic resins, subsequently a torsion screw has been designed.
\nIn order to find out relationships among the velocity, velocity gradient, and temperature gradient fields in the plasticization process of polymer, we presented the mathematical expressions for quantitative analysis of multi-field synergy based on momentum conservation equation and energy conservation equation.
\nFrom the knowledge of polymer rheology, we have obtained the Navier-Stokes equation derived from momentum conservation equation in the form of Eq. (1).
\nEq. (2) is obtained by further expansion.
\nwhere
where
Here defines the synergy angle
When the synergy angle
From Eqs. (2) and (3), we can also conclude that the pressure gradient is affected by the synergy angle
Almost all polymer processing unit operations require heat transfer processes such as energy exchange, heating, and cooling to facilitate phase-to-phase thermal and molecular mobility. Therefore, the study of energy balance and distribution has special significance in the process of melt flow. It is well known that the general energy conservation equation in the flow field can be represented in the form of Eq. (5).
\nBy further expansion, we obtain Eq. (6) as follows.
\nwhere
where
Here is defined as the synergy angle
In the case of the problem of a two-dimensional flat-plate steady-state boundary layer, Guo et al. [25, 26] have simplified the energy conservation equations into the dimensionless forms
\nwhere \n
where
By understanding the multi-field synergy effect in the heat and mass transfer process of polymer plasticization, we can construct a specific flow field so that the directions of velocity field and temperature gradient field are no longer perpendicular, and the flow field movement is more random. The schematic diagram is shown in Figure 1. In this way, it can facilitate phase-to-phase thermal and molecular mobility, so as to significantly improve heat transfer and molecular mixing, particularly for highly viscous multicomponent polymer melts with Bio or Nano filler. Based on this method, we can design a special screw configuration to divert the fluid particles and obtain the desired flow field. Here, we propose a new type of screw element, namely, torsion element, to stimulate the spiral or torsional flow, which is the most common way of disturbing or changing flow direction in nature.
\nThe synergy between velocity field and heat flow field: Parallel movement (a) and spiral movement (b).
In the following sections, we develop a novel torsion element-induced torsional flow into the flow field by adapting the field synergy principle. Then, we establish a three-dimensional physical and mathematical model with finite element method (FEM), and present results of computational fluid dynamics (CFD) simulations of the flow and heat transfer of a viscous polypropylene (PP) melt in the screw with torsion elements to confirm this field synergy method and compared them with the conventional screw in common use today.
\nThe geometrical configuration of the proposed torsion element is shown in Figure 2. The torsion channels are divided into N parts along the circumferential direction by torsion flights. Between every two adjacent torsion flights, there are two surfaces twisted by 90°along the axial direction. When polymer flows over the torsion channel, it is expected to undergo a torsional rotation (tumbling) under the forces generated from viscous friction with barrel wall and with the steering between two 90° twisted surfaces. As a result, spiral-shaped or torsional-shaped flow may occur in the torsion channel. In consequence, the intersection angle between the velocity and the heat flux will decrease to less than 90° compared with that in the standard screw channel, and then the synergic effect between the velocity vector and the temperature gradient will be improved.
\nThe geometrical configuration and flow line of particles for a torsion element.
Six screws with same length and diameter (designated by alphabetical A to F as shown in Figure 3) were employed in this work to verify the synergic effect of torsion element. Screws were constructed of two kinds of polymer plasticization elements: the torsion element and the screw element. Screws A to D had six torsion elements with regular arrangement in different orders. As control subjects, screw E is a conventional screw without torsion element and screw F is a torsional screw without screw elements. Table 1 presents a summary of the geometric parameters of simulation models.
\nThe geometrical configuration of various screws (with screw elements and torsion elements).
Parameters | \nDimensions (mm) | \n
---|---|
Length of screw | \n180 | \n
Diameter of screw | \n30 | \n
Diameter of barrel | \n30.4 | \n
Length of single torsion element | \n10 | \n
Lead of screw element | \n30 | \n
Inner diameter of screw | \n25.8 | \n
Geometric parameters of simulation models.
In this case, we assumed that the polymer fluid had non-isothermal transient laminar flow and was incompressible. No-slip conditions were adopted at the boundary. Polypropylene (PP) was chosen to be the model polymer due to its common use in polymer processing. Compared with viscous force, the inertial force can be neglected due to the high viscosity of PP. Therefore, the governing equations representing the flow field in this situation are shown in the form of Eqs. (11)–(13).
\nContinuity equation:
\nMomentum equation:
\nEnergy equation:
\nThe apparent viscosity of PP was described by the Carreau-approximate Arrhenius model (Eq. 14), which match most polymers, to consider the factors of both temperature and shear.
\nThe physical characteristics of the PP and screw material are listed in Tables 2 and 3, respectively. The choice of the polymer affects only the constants in the constitutive equation (Eq. (14)). Moreover, the Carreau-approximate Arrhenius model has been already validated for most polymer melts (e.g., polystyrene, polyethylene, and polyurethane.). Therefore, we assume modeling and simulated results based on the above conditions, which are generally applicable for most of the materials used in polymer processing.
\nDensity | \n735 kg/m3 | \n
Thermal conductivity | \n0.15 W/(m·K) | \n
Specific heat capacity | \n2100 J/(kg·K) | \n
Zero shear viscosity | \n26,470 Pa·s | \n
Non-Newtonian index | \n0.38 | \n
Natural time | \n2.15 s | \n
Coefficient of temperature sensibility | \n0.02 K−1 | \n
Reference temperature | \n513 K | \n
Physical parameters of the PP.
Density | \n8030 kg/m3 | \n
Thermal conductivity | \n16.27 W/(m·K) | \n
Specific heat capacity | \n502.4 J/(kg·K) | \n
Physical parameters of the screw.
In our work, ANSYS Polyflow 17.0 packaged software (ANSYS, Inc.) was adopted in the simulations. The 3D mesh systems for the screw and the fluid were created using the mesh superposition technique (MST). Figure 4 shows the 3D model for screw E. The fluid model and screw model were implemented through mesh refinement by hexahedral and tetrahedral elements, respectively. In addition, progressively refined meshes for the screw and fluid models were constructed to ensure that the simulation results were mesh-independent. Different screws had the same mesh refinement setting and, with the same fluid model, simulation results were displayed in the grid of fluid domain. Table 4 gives the flow and thermal boundary conditions used in this case.
\nThree-dimensional physical model of screw E.
Location | \nFlow boundary conditions | \nThermal boundary conditions | \n
---|---|---|
Inlet | \nSetting zero pressure | \n513 K | \n
Outlet | \nSetting zero pressure | \nHeat outlet | \n
Barrel wall | \nNo-slip wall | \n513 K | \n
Screw wall | \nScrew speeds: 40,60,80,100,120 r/min | \nFree boundary | \n
Boundary conditions.
Firstly, we investigated the axial melt temperature distribution by selecting different radial reference lines for these six screws as shown in Figure 5. From all the six screws, we can find that the temperature fluctuations decrease by the effect of torsion elements and the temperature difference between melt and barrel wall in the position of torsion elements is smaller than that of the position of screw elements. The reason for this phenomenon is heat transfer enhancement caused by the synergy effect between velocity and temperature gradient. We will prove this in the next section. Figure 6 shows the radial melt temperature distribution for screw B in the position of torsion and screw elements. For the position of torsion element, almost all the fluid is in a high-temperature region, more than 500°C, while the radial temperature for most fluid in the screw channels is below 500°C. Results indicated that the radial temperature difference in the position of torsion element is much lower compared with that of the position of screw elements, no matter before or after the torsion element. It can be concluded that the torsion element can achieve more uniform temperature distribution than the screw element.
\nRadial and axial temperature distribution for the different screws at 40 r/min. (1) r = 14.5 mm; (2) r = 14.0 mm; (3) r = 13.5 mm; (4) r = 13.0 mm.
Temperature contours (left) and melt temperature profiles (right) across the melt flow with the magnitude of fluctuations for screw B at different x-positions at 40 r/min.
In order to verify the field synergy effect, we calculated the mean field synergy angle between temperature gradient and velocity fields and the Nusselt number at different screw speeds for these six screws as shown in Figure 7. It can be seen that the Nusselt number increases with screw speed, which is a well-known fact. Results also indicated that conventional screw E without torsion elements has the largest mean field synergy angle and smallest Nusselt number, while screw F without screw elements has the smallest mean field synergy angle and largest Nusselt number, which means the smaller the field synergy angle, the larger the Nusselt number. However, there are little difference of values in field synergy angle and Nusselt number for the screws A, B, C and D. This is because all these four screws have the same six torsion elements, which bring about almost the same influence on the variations of field synergy angle, that is, the arrangement of torsion elements in the screw has little effect on the field synergy angle. Therefore, it can be inferred that the screws equipped with torsion elements show better convective heat transfer capacity compared with the conventional screw, which then bring about a good melt temperature uniformity.
\nA plot of the mean field synergy angle (left) and Nusselt number (right) versus screw speed for various screws.
In addition, Figure 8 shows the local field synergy angle and the local heat transfer coefficient at different cross sections for screw A. Results also indicated that the local regions with torsion elements have larger heat transfer coefficients and smaller field synergy angles than the local regions with screw elements. Besides, the local convective heat transfer was found to be inversely proportional to the local field synergy angle between velocity and temperature gradient.
\nA plot of the local field synergy angle versus the local heat transfer coefficient (left) and the local field synergy angle contours at different cross sections (right) for screw A at a screw speed of 80 r/min.
The contours of the local field synergy angle at different positions further show that most of the local synergy angle distributions at the cross sections of torsion elements alternate between larger and smaller synergy angles, while those at the cross sections of screw elements are close to 90.0°.
\nFigure 9 shows the dependence of the Nusselt number on the field synergy angle for various screw speeds and shows that the Nusselt number increases with decreasing field synergy angle. It can be inferred that the Nusselt number is inversely interrelated with the synergy angle β. When the confidence level is 95%, its value is limited to a relatively narrow confidence band. Furthermore, the Pearson correlation coefficient is about −0.7, which indicates a strong negative correlation. These results demonstrate that the coupling relationship between temperature gradient and velocity fields has a significant effect on the convective heat transfer of the polymer itself in a polymer plasticization process.
\nThe dependence of the Nusselt number on the field synergy angle for various screw speeds. The inset is the Pearson correlation coefficient.
Accordingly, the field synergy principle is able to explain the enhancement of heat transfer brought about by the torsion elements.
\nAs stated previously, the synergy effect between velocity and temperature gradient in the torsion element is realized by constructing a spiral or torsional flow in the flow field. In order to verify the existence of torsional-spiral shaped flow, we investigated the fluid flow characteristics in the region of both torsion and screw elements as shown in Figure 10.
\nThe streamline contours in screws A, B, and E at a screw speed of 40 r/min in the axial direction (a) and the cross section of the torsion element (b).
Figure 10(a) shows the streamline contours along the axial direction for screws A, B, and E. We can see that spiral-shaped flow occurs in the position of torsion elements for both screws A and B, which cannot be achieved in screw E. In this spiral-shaped flow, the velocity directions are changing along the flow direction and mass transfer is enhanced in the radial direction, that is, the synergy angles between velocity and thermal flow fields are no longer perpendicular to each other, which confirms the assumption shown in Figures 1 and 2. Figure 10(b) shows the cross sections in the torsion and screw elements. And results indicated that there are vortexes in the torsion channel, while there are just plug flows without radial convection in the screw channel.
\nTherefore, it can be inferred that the torsion element improves the synergy between velocity and temperature gradient by inducing torsional flow, and then enhances heat transfer in the screw plasticization process.
\nThe performance of screw with torsion elements in the polymer plasticization process has been verified though numerical analysis. Furthermore, the mixing and heat transfer performances of the newly designed screw configuration based on field synergy principle were evaluated through extrusion runs and experimental data. Materials used were polypropylene (PP) and polystyrene (PS) bi-phase polymer composite mix.
\nFigure 11 shows the particle size distribution of PS (PP: PS = 100:10, % wt/wt) at the screw outlet; more specifically, Figure 11(a) is that of torsional screw with six torsion elements and Figure 11(b) is that of conventional screw without torsion element. The particle size distribution of PS fits Gaussian distribution. On the other hand, the relative frequencies of particle size in torsion screw are more concentrated in a narrow range [0–50 μm] than those in conventional screw. This can be further validated from the scanning electron microscope (SEM) pictures shown in Figure 11(a) and Figure 11(b). SEM pictures clearly show that the particles of PS in torsional screw are finer and the particle sizes are smaller than those in conventional screw. Average particle size (
Particle size distribution in a PP/PS bi-phase composite in the outlet of the screws.
Figure 12 shows the variation of heat transfer coefficient
Heat transfer coefficient (left) and outlet radial temperature distribution (right) of the plasticization system for screws.
From the outlet radial temperature distribution, it can be found that the melt temperature in the center of die is higher than the temperature near the barrel walls, which is due to the viscous dissipation of polymers. Therefore, an effective heat transfer is needed in order to evenly distribute the thermal energy among the polymer melt. In addition, the radial temperature difference of torsional screw is 15°C, whereas the radial temperature difference of conventional screw is 20°C, which is 25% higher than that of torsional screw. As the experiment data indicate that the radial temperature difference of melt decreases in the torsional configured screw, it can be concluded that the torsional configuration has a superior heat and mass transfer performance to achieve better temperature distribution than traditional screw, which is also in agreement with the simulation results.
\nOne of the fundamental questions of non-uniform heat and mass transfer in viscous fluid was addressed by proposing a radial torsional flow pattern, by designing a torsion element and validating the same in a melt-phase polymer extrusion process. The synergistic interaction mechanisms between velocity and velocity gradient and velocity and temperature gradient have been investigated by considering theoretical and numerical aspects, which provides a new perspective to understand the polymer processing. Considering the multi-field synergy, a new design concept of torsion screw configuration has been proposed to facilitate phase-to-phase thermal and molecular mobility.
\nThe spiral-shaped torsional flow induced by torsion configurations in a polymer channel changes the radial velocity direction, which in turn improves the interaction between velocity and temperature fields and helps to achieve good heat transfer and temperature homogeneity. The new torsion elements and their arrangement provide a novel pathway to achieve good thermal management of polymer melt by enhancing multi-field coupling. These results can be achieved to guide the screw design used for preparing high-performance composites, especially heat-sensible and biodegradable nanocomposites or microcellular foam controlled by temperature.
\nThis work was supported by the National Natural Science Foundation of China (grant number 51576012). Support from China Scholarship Council is also gratefully acknowledged for Ranran Jian’s joint PhD grant. fluid density, kg/m3 fluid velocity, m/s stress, Pa pressure, Pa constant-volume specific heat capacity, J/(kg·K) constant-pressure specific heat capacity, J/(kg·K) thermal conductivity, W/(m·K) fluid temperature, K Cartesian coordinates, m velocity boundary layer thickness, m thermal boundary layer thickness, m velocity vector, m/s velocity gradient vector, s−1 temperature gradient vector, K/m mean velocity of fluid, m/s fluid viscosity, Pa·s heat transfer coefficient, W/(m2·K) Reynolds number Euler number Prandtl number Nusselt number synergy angle between the velocity gradient and the velocity, ° synergy angle between the temperature gradient and the velocity, ° pressure, Pa apparent viscosity, Pa·s zero shear viscosity, Pa·s shear rate, s−1 natural time, s temperature sensibility coefficient, K−1 non-Newtonian index reference temperature, K
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The decision to make an ALCA or a CLCA should ideally be taken by the LCA practitioner after discussions with the client and possibly with other stakeholders and colleagues.",book:{id:"8156",slug:"sustainability-assessment-at-the-21st-century",title:"Sustainability Assessment at the 21st century",fullTitle:"Sustainability Assessment at the 21st century"},signatures:"Tomas Ekvall",authors:[{id:"293149",title:"Prof.",name:"Tomas",middleName:null,surname:"Ekvall",slug:"tomas-ekvall",fullName:"Tomas Ekvall"}]},{id:"49907",title:"Carbon Dioxide Geological Storage (CGS) – Current Status and Opportunities",slug:"carbon-dioxide-geological-storage-cgs-current-status-and-opportunities",totalDownloads:3129,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"Carbon dioxide sequestration has gained a great deal of global interest because of the needs and applications of mitigation strategy in many areas of human endeavors including capture and reduction of CO2 emission into atmosphere, oil and gas enhanced production, and CO2 geological storage. In recent years, many developed countries as well as some developing ones have extensively investigated all aspects of the carbon dioxide geological storage (CGS) process such as the potential of storage sites, understanding the behavior of CO2, and its interaction with various formations comprising trapping mechanisms, flow pattern, and interactions with formation rocks and so on. This review presents a summary of recent research efforts on storage capacity estimation techniques in most prominent storage options (depleted oil and gas reservoir, saline aquifers and coal beds), modeling and simulation means followed by monitoring and verification approaches. An evaluation of the more interesting techniques which are gaining attention in each part is discussed.",book:{id:"4697",slug:"greenhouse-gases",title:"Greenhouse Gases",fullTitle:"Greenhouse Gases"},signatures:"Kakouei Aliakbar, Vatani Ali, Rasaei Mohammadreza and Azin Reza",authors:[{id:"177143",title:"Ph.D. Student",name:"Aliakbar",middleName:null,surname:"Kakouei",slug:"aliakbar-kakouei",fullName:"Aliakbar Kakouei"},{id:"177149",title:"Dr.",name:"Mohammadreza",middleName:null,surname:"Rasaei",slug:"mohammadreza-rasaei",fullName:"Mohammadreza Rasaei"},{id:"177150",title:"Dr.",name:"Reza",middleName:null,surname:"Azin",slug:"reza-azin",fullName:"Reza Azin"},{id:"177151",title:"Dr.",name:"Ali",middleName:null,surname:"Vatani",slug:"ali-vatani",fullName:"Ali Vatani"}]},{id:"38103",title:"GIS for Environmental Problem Solving",slug:"gis-for-environmental-problem-solving",totalDownloads:12382,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"2168",slug:"sustainable-development-authoritative-and-leading-edge-content-for-environmental-management",title:"Sustainable Development",fullTitle:"Sustainable Development - Authoritative and Leading Edge Content for Environmental Management"},signatures:"Koushen Douglas Loh and Sasathorn Tapaneeyakul",authors:[{id:"10635",title:"Dr.",name:"Koushen Douglas",middleName:null,surname:"Loh",slug:"koushen-douglas-loh",fullName:"Koushen Douglas Loh"},{id:"147886",title:"Ms.",name:"Sasathorn",middleName:null,surname:"Tapaneeyakul",slug:"sasathorn-tapaneeyakul",fullName:"Sasathorn Tapaneeyakul"}]},{id:"69954",title:"Green Building Rating Systems as Sustainability Assessment Tools: Case Study Analysis",slug:"green-building-rating-systems-as-sustainability-assessment-tools-case-study-analysis",totalDownloads:1495,totalCrossrefCites:2,totalDimensionsCites:4,abstract:"Building performance and occupants’ comfort lie at the core of building design targets. Principles of green architecture and building physics are not given enough thought and consideration. In the best cases, some thought is given to such factors but without a scientific methodology, which takes into consideration appropriate climatic data and appropriate assessment tools. Most importantly, the interference of the environmentalist in architecture projects comes usually very late in the design processes. Facing these facts has driven most countries to adopt official strategies and policies to deal with building’s performance. The rating systems are among these initiatives. The author of this chapter adapts a detailed methodology to aid the integration of the principles of the green architecture in the early stages of design using rating systems. The Leadership in Energy and Environmental Design (LEED) 1 that was developed in the USA by the U.S. Green Building Council (USGBC) for Core and Shell has been employed as the main design target. This chapter presents a brief about the world green initiatives and discusses the results of applying the methodology of integrating the green architectural principles at the early stages of design processes—through precedent analysis.",book:{id:"8156",slug:"sustainability-assessment-at-the-21st-century",title:"Sustainability Assessment at the 21st century",fullTitle:"Sustainability Assessment at the 21st century"},signatures:"Mady Mohamed",authors:[{id:"271848",title:"Dr.",name:"Mady",middleName:null,surname:"Mohamed",slug:"mady-mohamed",fullName:"Mady Mohamed"}]},{id:"38111",title:"Evaluation of Soil Quality Parameters Development in Terms of Sustainable Land Use",slug:"evaluation-of-soil-quality-parameters-development-in-terms-of-sustainable-land-use",totalDownloads:3233,totalCrossrefCites:4,totalDimensionsCites:10,abstract:null,book:{id:"2168",slug:"sustainable-development-authoritative-and-leading-edge-content-for-environmental-management",title:"Sustainable Development",fullTitle:"Sustainable Development - Authoritative and Leading Edge Content for Environmental Management"},signatures:"Danica Fazekašová",authors:[{id:"147786",title:"Associate Prof.",name:"Danica",middleName:null,surname:"Fazekašová",slug:"danica-fazekasova",fullName:"Danica Fazekašová"}]}],onlineFirstChaptersFilter:{topicId:"143",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:0,limit:8,total:null},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:287,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:10,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403",scope:"Artificial Intelligence (AI) is a rapidly developing multidisciplinary research area that aims to solve increasingly complex problems. In today's highly integrated world, AI promises to become a robust and powerful means for obtaining solutions to previously unsolvable problems. This Series is intended for researchers and students alike interested in this fascinating field and its many applications.",coverUrl:"https://cdn.intechopen.com/series/covers/14.jpg",latestPublicationDate:"May 18th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:9,editor:{id:"218714",title:"Prof.",name:"Andries",middleName:null,surname:"Engelbrecht",slug:"andries-engelbrecht",fullName:"Andries Engelbrecht",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRNR8QAO/Profile_Picture_1622640468300",biography:"Andries Engelbrecht received the Masters and PhD degrees in Computer Science from the University of Stellenbosch, South Africa, in 1994 and 1999 respectively. He is currently appointed as the Voigt Chair in Data Science in the Department of Industrial Engineering, with a joint appointment as Professor in the Computer Science Division, Stellenbosch University. Prior to his appointment at Stellenbosch University, he has been at the University of Pretoria, Department of Computer Science (1998-2018), where he was appointed as South Africa Research Chair in Artifical Intelligence (2007-2018), the head of the Department of Computer Science (2008-2017), and Director of the Institute for Big Data and Data Science (2017-2018). 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He is a full professor of signal processing and pattern recognition and is head of the Signals and Communications Department at ULPGC, teaching from 2001 on subjects on signal processing and learning theory. His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. He is the founder of The IEEE IWOBI conference series and the president of its Steering Committee, as well as the founder of both the InnoEducaTIC and APPIS conference series. He is an evaluator of project proposals for the European Union (H2020), Medical Research Council (MRC, UK), Spanish Government (ANECA, Spain), Research National Agency (ANR, France), DAAD (Germany), Argentinian Government, and the Colombian Institutions. He has been a reviewer in different indexed international journals (<70) and conferences (<250) since 2001. 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He won the “Catedra Telefonica” Awards in Modality of Knowledge Transfer, 2017, 2018, and 2019 editions, and awards in Modality of COVID Research in 2020.\n\nPublic References:\nResearcher ID http://www.researcherid.com/rid/N-5967-2014\nORCID https://orcid.org/0000-0002-4621-2768 \nScopus Author ID https://www.scopus.com/authid/detail.uri?authorId=6602376272\nScholar Google https://scholar.google.es/citations?user=G1ks9nIAAAAJ&hl=en \nResearchGate https://www.researchgate.net/profile/Carlos_Travieso",institutionString:null,institution:{name:"University of Las Palmas de Gran Canaria",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"13633",title:"Prof.",name:"Abdelhamid",middleName:null,surname:"Mellouk",slug:"abdelhamid-mellouk",fullName:"Abdelhamid Mellouk",profilePictureURL:"https://mts.intechopen.com/storage/users/13633/images/1567_n.jpg",institutionString:null,institution:{name:"Paris 12 Val de Marne 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He has (co)authored more than 150 publications in indexed journals, international conferences and book chapters, 1 book (in Greek), 3 edited books, and 5 journal special issues. His publications have more than 2100 citations with h-index 27 (GoogleScholar). His research interests include computer/machine vision, machine learning, pattern recognition, computational intelligence. \nDr. Papakostas served as a reviewer in numerous journals, as a program\ncommittee member in international conferences and he is a member of the IAENG, MIR Labs, EUCogIII, INSTICC and the Technical Chamber of Greece (TEE).",institutionString:null,institution:{name:"International Hellenic University",institutionURL:null,country:{name:"Greece"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"1177",title:"Prof.",name:"Antonio",middleName:"J. 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Dr Ventura also holds the positions of Affiliated Professor at Virginia Commonwealth University (Richmond, USA) and Distinguished Adjunct Professor at King Abdulaziz University (Jeddah, Saudi Arabia). Additionally, he is deputy director of the Andalusian Research Institute in Data Science and Computational Intelligence (DaSCI) and heads the Knowledge Discovery and Intelligent Systems Research Laboratory. He has published more than ten books and over 300 articles in journals and scientific conferences. Currently, his work has received over 18,000 citations according to Google Scholar, including more than 2200 citations in 2020. In the last five years, he has published more than 60 papers in international journals indexed in the JCR (around 70% of them belonging to first quartile journals) and he has edited some Springer books “Supervised Descriptive Pattern Mining” (2018), “Multiple Instance Learning - Foundations and Algorithms” (2016), and “Pattern Mining with Evolutionary Algorithms” (2016). He has also been involved in more than 20 research projects supported by the Spanish and Andalusian governments and the European Union. He currently belongs to the editorial board of PeerJ Computer Science, Information Fusion and Engineering Applications of Artificial Intelligence journals, being also associate editor of Applied Computational Intelligence and Soft Computing and IEEE Transactions on Cybernetics. Finally, he is editor-in-chief of Progress in Artificial Intelligence. He is a Senior Member of the IEEE Computer, the IEEE Computational Intelligence, and the IEEE Systems, Man, and Cybernetics Societies, and the Association of Computing Machinery (ACM). Finally, his main research interests include data science, computational intelligence, and their applications.",institutionString:null,institution:{name:"University of Córdoba",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"111683",title:"Prof.",name:"Elmer P.",middleName:"P.",surname:"Dadios",slug:"elmer-p.-dadios",fullName:"Elmer P. 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