Zekeriyaköy Population for the last 19 years.
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"7983",leadTitle:null,fullTitle:"Psychosomatic Medicine",title:"Psychosomatic Medicine",subtitle:null,reviewType:"peer-reviewed",abstract:"Modern psychosomatic medicine is a comprehensive framework for a holistic (biopsychosocial) perspective of illnesses and patient care. It highlights the influence of psychosocial factors on health, the interaction between psychosocial and biological factors in the course and outcome of diseases, and a whole perspective with respect to treatments. This book discusses holistic approaches to both organic and psychopathological diseases. Over three sections, authors address psychosomatic approaches to fibromyalgia, palliative care, anxiety and depression, obesity, and traumatic stress disorders.",isbn:"978-1-83968-233-9",printIsbn:"978-1-83968-232-2",pdfIsbn:"978-1-83968-234-6",doi:"10.5772/intechopen.77813",price:119,priceEur:129,priceUsd:155,slug:"psychosomatic-medicine",numberOfPages:210,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"4eabb8ae6669b096f822a3ebd57ef59d",bookSignature:"Ignacio Jáuregui Lobera",publishedDate:"November 4th 2020",coverURL:"https://cdn.intechopen.com/books/images_new/7983.jpg",numberOfDownloads:6098,numberOfWosCitations:0,numberOfCrossrefCitations:8,numberOfCrossrefCitationsByBook:1,numberOfDimensionsCitations:11,numberOfDimensionsCitationsByBook:1,hasAltmetrics:1,numberOfTotalCitations:19,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"November 18th 2019",dateEndSecondStepPublish:"February 19th 2020",dateEndThirdStepPublish:"April 19th 2020",dateEndFourthStepPublish:"July 8th 2020",dateEndFifthStepPublish:"September 6th 2020",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"323887",title:"Prof.",name:"Ignacio",middleName:null,surname:"Jáuregui-Lobera",slug:"ignacio-jauregui-lobera",fullName:"Ignacio Jáuregui-Lobera",profilePictureURL:"https://mts.intechopen.com/storage/users/323887/images/system/323887.png",biography:null,institutionString:"Pablo de Olavide University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"7",totalChapterViews:"0",totalEditedBooks:"4",institution:{name:"Pablo de Olavide University",institutionURL:null,country:{name:"Spain"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1061",title:"Psychiatry",slug:"mental-and-behavioural-disorders-and-diseases-of-the-nervous-system-psychiatry"}],chapters:[{id:"72089",title:"The Network Paradigm: New Niches for Psychosomatic Medicine",doi:"10.5772/intechopen.91885",slug:"the-network-paradigm-new-niches-for-psychosomatic-medicine",totalDownloads:672,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"Psychosomatic medicine, as a philosophical frame and practical approach of the diagnostic and therapeutical agency, had been undergone several renewals and reframing in the past. We overview the history of psychosomatics and map its branches. Psychoanalytic and psychodynamic frameworks, the Engelian biopsychosocial concept, the paradigm of behavioral medicine, the clinical psychophysiological research background, the clinical fields of PNI, psychocardiology, biobehavioral oncology, the so-called mind-body medicine, and stress medicine frameworks reflect a converging pluralism. Psychoneuroimmunology offers a comprehensive framework to analyze key issues of psychosomatics in a social neuroscience framework and to demonstrate the significance of the network approach in bridging the gap between psychosomatics and biomedicine. Network medicine creates a shared denominator for analyzing socioeconomic, interpersonal, life event-based narrative factors together with psychophysiological features of the clinical and health psychological problems and promotes convergence of psychosomatics, biomedicine, and lifestyle medicine, too. On the other side, psychosomatic medicine as a particular professional medical specialization is not universal at all. In Europe, one can find such specialization only in Germany, while psychotherapy applied by somatic experts is practiced in wider circles. Finally, we explore the new niches for psychosomatic orientation offered by integrative frameworks like lifestyle medicine and network medicine.",signatures:"Imre Lázár",downloadPdfUrl:"/chapter/pdf-download/72089",previewPdfUrl:"/chapter/pdf-preview/72089",authors:[{id:"241863",title:"Prof.",name:"Imre",surname:"Lázár",slug:"imre-lazar",fullName:"Imre Lázár"}],corrections:null},{id:"73043",title:"Psychological and Societal Implications of Projecting the Shadow on the Feminine in Tibetan Buddhist Contexts",doi:"10.5772/intechopen.93297",slug:"psychological-and-societal-implications-of-projecting-the-shadow-on-the-feminine-in-tibetan-buddhist",totalDownloads:581,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Idealizing and medicalizing of methods ascribed to Buddhism has led to individualizing their structural and societal challenges. Although the long-undervalued need for introspection may get addressed, people are now caught under the cloak of spirituality hoping for quick enlightenment or a panacea solving mental diseases. Thus, at this point, the impact of decontextualizing concepts, unreflectively copying feudal structures into Tibetan Buddhist seminar- and meditation-centers, as well as of lacking knowledge required for the gradual application-oriented learning processes taught in traditional Buddhist philosophy have become clear. This shows in recent testimony of economical, psychological, and physical abuse in international Tibetan Buddhist organizations. The violence against individuals and man-made trauma in such contexts need to get analyzed before the background of neologisms, that is concepts allowing for arbitrariness and violence in the name of spirituality, as well as of the sophisticated systems of rationalizing damage and silencing trauma and victims. Furthermore, though those in the ‘inner circles’ run the risk of traumatization and of being held accountable, it is women who are at higher risk, particularly those who engage in secret relationships. Thus, in terms of treatment, the collectively projecting the shadow on the feminine, leading to an attitude of exploitation and control against women, requires consideration.",signatures:"Anne Iris Miriam Anders",downloadPdfUrl:"/chapter/pdf-download/73043",previewPdfUrl:"/chapter/pdf-preview/73043",authors:[{id:"319312",title:"Dr.",name:"Anne Iris Miriam",surname:"Anders",slug:"anne-iris-miriam-anders",fullName:"Anne Iris Miriam Anders"}],corrections:null},{id:"71625",title:"Psychosomatic Approach to Fibromyalgia Syndrome: Medical, Psychological, and Social Aspects",doi:"10.5772/intechopen.91768",slug:"psychosomatic-approach-to-fibromyalgia-syndrome-medical-psychological-and-social-aspects",totalDownloads:811,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Management of patients who describe chronic pain all over the body, associated with a range of symptoms as sleep disturbance, overwhelming fatigue, alteration in mood, or psychological distress that worsens the quality of life, is often complex and challenging. This syndrome has been named by terms such as “neurasthenia,” “fibrositis,” and “fibromyalgia”. At the present time, fibromyalgia is considered the most common central sensitivity syndrome, affecting over 5% of the population, being often observed in people with rheumatic conditions. While typically presenting in middle-aged women, fibromyalgia can affect both sexes at any age. The causes of fibromyalgia remain unknown. Significant research findings have focused on dysfunction of central pain processing, with defects in the ascending and descending pain pathways leading to increased pain perception. There are two methods used in the diagnosis of fibromyalgia: criteria-based diagnosis and clinical diagnosis. Although fibromyalgia defies definitively efficacious management, much evidence underlies the importance of treating the psychological factors that affect pain management process. The primary purpose of this paper is to provide a psychosomatic approach to fibromyalgia from three points of view of processing: the viewpoint of the medical profession, the position of the psychologist, and finally the way of thinking of people.",signatures:"José Vicente Martínez-Quiñones, Mar Martínez Gamarra and Ignacio Jáuregui-Lobera",downloadPdfUrl:"/chapter/pdf-download/71625",previewPdfUrl:"/chapter/pdf-preview/71625",authors:[{id:"323887",title:"Prof.",name:"Ignacio",surname:"Jáuregui-Lobera",slug:"ignacio-jauregui-lobera",fullName:"Ignacio Jáuregui-Lobera"},{id:"277976",title:"Ph.D.",name:"José Vicente",surname:"Martínez Quiñones",slug:"jose-vicente-martinez-quinones",fullName:"José Vicente Martínez Quiñones"},{id:"291065",title:"Dr.",name:"M",surname:"Martínez Gamarra",slug:"m-martinez-gamarra",fullName:"M Martínez Gamarra"}],corrections:null},{id:"72909",title:"Psychosomatic Medicine and Palliative Care",doi:"10.5772/intechopen.93154",slug:"psychosomatic-medicine-and-palliative-care",totalDownloads:492,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Psychosomatic medicine (MP) and palliative care are disciplines with history and both are based in the scientific world. Although the psychosomatic diagnosis is exclusionary, it can help palliative care to be more effective. The influence of the psychosomatic in the palliative exists. According to all the bibliography available in the electronic databases, psychosomatic medicine is a biopsychosocial model related to both physical and psychosocial factors, which helps improve the care of patients with advanced cancer in palliative care (improved survival, quality of life, reduces the burden on caregivers). It helps analyze and address psychiatric disorders, as well as in the control of complex symptoms such as life-threatening anxiety, depression or delirium. Therefore, both medical disciplines are related from the beginning and help to the quality of life of terminally ill patients.",signatures:"Manuel Mejías-Estévez, Rocio Dominguez Álvarez and Ignacio Jauregi Lobera",downloadPdfUrl:"/chapter/pdf-download/72909",previewPdfUrl:"/chapter/pdf-preview/72909",authors:[{id:"323887",title:"Prof.",name:"Ignacio",surname:"Jáuregui-Lobera",slug:"ignacio-jauregui-lobera",fullName:"Ignacio Jáuregui-Lobera"},{id:"321713",title:"Dr.",name:"Manuel",surname:"Mejías-Estévez",slug:"manuel-mejias-estevez",fullName:"Manuel Mejías-Estévez"},{id:"323475",title:"Dr.",name:"Rocio",surname:"Dominguez",slug:"rocio-dominguez",fullName:"Rocio Dominguez"}],corrections:null},{id:"73456",title:"Assessing the Effectiveness of Brief and Low Intensity Psychological Interventions for Medically Unexplained Symptoms and Health Anxiety: A Systematic Review of the Literature",doi:"10.5772/intechopen.93912",slug:"assessing-the-effectiveness-of-brief-and-low-intensity-psychological-interventions-for-medically-une",totalDownloads:606,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:1,abstract:"This chapter presents a systematic review of the literature to assess the effectiveness of brief psychological interventions for medically unexplained symptoms (MUS)/somatic symptom disorder, non-cardiac chest pain, and illness anxiety disorder or health anxiety (HA). Google Scholar, PubMed, and Web of Science were searched as data sources. Reference lists were subsequently examined for other relevant articles. Studies were assessed according to specified inclusion criteria and extracted according to PRISMA guidelines. A total of 23 studies were included in the final synthesis. Significant effects for intervention groups relative to control groups were reported in 19 studies, whilst 4 studies did not determine any significant benefits of interventions compared with controls. All of the brief interventions (CBT, psychosocial, psychophysiological, psychosomatic, relaxation and group therapy), with the exception of metaphor therapy, showed significant effects relative to controls in at least one study. The evidence suggests that brief psychological interventions, more specifically time limited CBT based interventions may be effective in treating HA and MUS with psychological distress. Findings are comparable with other reviews. Future research may facilitate the piloting of an intervention, and there remains a need to provide more robust evidence of cost effectiveness.",signatures:"Orla McDevitt-Petrovic and Karen Kirby",downloadPdfUrl:"/chapter/pdf-download/73456",previewPdfUrl:"/chapter/pdf-preview/73456",authors:[{id:"325840",title:"Dr.",name:"Karen",surname:"Kirby",slug:"karen-kirby",fullName:"Karen Kirby"},{id:"325841",title:"Dr.",name:"Orla",surname:"McDevitt-Petrovic",slug:"orla-mcdevitt-petrovic",fullName:"Orla McDevitt-Petrovic"}],corrections:null},{id:"71570",title:"Psychosomatic Inpatient Rehabilitation for People with Depression in Germany",doi:"10.5772/intechopen.91923",slug:"psychosomatic-inpatient-rehabilitation-for-people-with-depression-in-germany",totalDownloads:615,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"In Germany, inpatient therapy for depression mainly takes place in either health insurance-financed psychiatric hospitals, or in pension insurance-financed, psychotherapy-focused, psychosomatic rehabilitation hospitals. In psychiatric hospitals, the diagnosis is made according to the International Classification of Diseases (ICD), and therapeutic attempts are made to achieve remission, whereas in rehabilitation hospitals, the International Classification of Functioning, Disability and Health (ICF) plays an essential diagnostic role. Accordingly, the main German pension insurance, Deutsche Rentenversicherung, has developed a rehabilitation therapy standard for depressive disorders. In this chapter, we focus on the psychotherapeutic inpatient rehabilitation for patients with depression based on an example of a specialized psychotherapeutic hospital. This example illustrates how psychotherapeutic inpatient rehabilitation can be tailored to the individual’s needs and may include any of the following therapeutic modalities: Cognitive Behavior Therapy (CBT), Schema Therapy, Cognitive Behavioral Analysis System of Psychotherapy (CBASP), pharmacotherapy, group therapy for comorbid conditions, skills training, psychoeducation, occupational therapy (OT), movement therapy, physiotherapy, music therapy, social work, family work, and self-help groups. People with depression may benefit from this service model of psychosomatic inpatient rehabilitation beyond symptom remission, as it focuses on increasing people’s functional level as well as their quality of life.",signatures:"Ralf F. Tauber, Carola Nisch, Mutahira M. Qureshi, Olivia Patsalos and Hubertus Himmerich",downloadPdfUrl:"/chapter/pdf-download/71570",previewPdfUrl:"/chapter/pdf-preview/71570",authors:[{id:"231568",title:"Dr.",name:"Hubertus",surname:"Himmerich",slug:"hubertus-himmerich",fullName:"Hubertus Himmerich"},{id:"275055",title:"Dr.",name:"Mutahira Moqueet",surname:"Qureshi",slug:"mutahira-moqueet-qureshi",fullName:"Mutahira Moqueet Qureshi"},{id:"318584",title:"Dr.",name:"Ralf F.",surname:"Tauber",slug:"ralf-f.-tauber",fullName:"Ralf F. Tauber"},{id:"318585",title:"Dr.",name:"Carola",surname:"Nisch",slug:"carola-nisch",fullName:"Carola Nisch"},{id:"318586",title:"Ms.",name:"Olivia",surname:"Patsalos",slug:"olivia-patsalos",fullName:"Olivia Patsalos"}],corrections:null},{id:"71448",title:"Emotional Eating and Obesity",doi:"10.5772/intechopen.91734",slug:"emotional-eating-and-obesity",totalDownloads:1037,totalCrossrefCites:6,totalDimensionsCites:8,hasAltmetrics:1,abstract:"The first time that terms such as food addiction and addictive eating were mentioned was in 1956, in an article by T.G. Randolph. Recently, from a psychosomatic point of view, some authors have linked obesity and food addiction. Along with the concept of food addiction (derived from the similarities between the consumption of certain foods and “substance addictions”), a couple of questions seem to arise: What if it’s not just the particular food (the substance) that we are addicted to? Could it be that we are addicted to something else that makes us eat it? Thus, the concept of eating addiction has its own set of particulars. It brings the attention back to the individual and not the external substance (the food or ingredient). The focus on confronting the obesity problem should be moved away from the food itself (the addictive substance) to the person’s act of eating (the addictive behavior). Undoubtedly, there are many links between emotions and overweight/obesity. This chapter aims to review the current state of this field of study which is the emotional basis of obesity (at least a particular case of obesity and weight-related disorders).",signatures:"Ignacio Jáuregui-Lobera and Marian Montes-Martínez",downloadPdfUrl:"/chapter/pdf-download/71448",previewPdfUrl:"/chapter/pdf-preview/71448",authors:[{id:"323887",title:"Prof.",name:"Ignacio",surname:"Jáuregui-Lobera",slug:"ignacio-jauregui-lobera",fullName:"Ignacio Jáuregui-Lobera"},{id:"316455",title:"Mrs.",name:"Marian",surname:"Montes-Martínez",slug:"marian-montes-martinez",fullName:"Marian Montes-Martínez"}],corrections:null},{id:"72157",title:"Post-Traumatic Stress Disorder in Children and Adolescents: Some Recent Research Findings",doi:"10.5772/intechopen.92284",slug:"post-traumatic-stress-disorder-in-children-and-adolescents-some-recent-research-findings",totalDownloads:772,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:"Childhood trauma can have a profound effect on development, with a lifelong impact on physical growth, psychological development, and mental health. This chapter provides a framework for adolescent health professionals to understand the impacts of traumatic stress on children and adolescents. This chapter mainly takes the Wenchuan Earthquake studies in China as an example, and reviews recent research findings on epidemiological characteristics of PTSD and related mental disorders, as well as on possible influencing factors and mechanisms for post-traumatic adaptation in children and adolescents. Important intervention strategies for PTSD in children and adolescents are introduced. Prospects for future research are also discussed.",signatures:"Yuanyuan Li, Ya Zhou, Xiaoyan Chen, Fang Fan, George Musa and Christina Hoven",downloadPdfUrl:"/chapter/pdf-download/72157",previewPdfUrl:"/chapter/pdf-preview/72157",authors:[{id:"315838",title:"Ph.D. Student",name:"Yuanyuan",surname:"Li",slug:"yuanyuan-li",fullName:"Yuanyuan Li"},{id:"317902",title:"Prof.",name:"Christina",surname:"Hoven",slug:"christina-hoven",fullName:"Christina Hoven"},{id:"317903",title:"Prof.",name:"Fang",surname:"Fan",slug:"fang-fan",fullName:"Fang Fan"},{id:"317904",title:"Dr.",name:"Musa",surname:"George",slug:"musa-george",fullName:"Musa George"},{id:"317905",title:"Ms.",name:"Xiaoyan",surname:"Chen",slug:"xiaoyan-chen",fullName:"Xiaoyan Chen"},{id:"319851",title:"Dr.",name:"Ya",surname:"Zhou",slug:"ya-zhou",fullName:"Ya Zhou"}],corrections:null},{id:"72923",title:"Use of Falun Gong to Address Traumatic Stress among Marginalized Clients",doi:"10.5772/intechopen.93301",slug:"use-of-falun-gong-to-address-traumatic-stress-among-marginalized-clients",totalDownloads:513,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"Although mental health service providers have focused on the effects of trauma and related interventions for decades, little is known about pervasive and historic trauma, particularly for socially marginalized individuals. Thus, clinical issues associated with sociopolitical oppression have been under-investigated. Coupled with the lack of sufficient cultural competence when working with diverse clients, mainstream clinicians frequently lack adequate case conceptualization skills and culturally sensitive interventions to assist clients from diverse backgrounds. Using traumatic stress as a framework for exploring evidence-based interventions to address long-term, pervasive marginalization and its psychological effects, the authors propose that mindfulness techniques are particularly beneficial to this client population. The authors reviewed culture-centered interventions to address traumatic stress for marginalized client populations, focusing on the mindfulness practice of Falun Gong. Recommendations for practice include the inclusion of traumatic stress theory and techniques in pre-service training, professional development training for practitioners focusing on mindfulness techniques with clients assessed with historical trauma, and Web-based training for clinical faculty to enhance their knowledge about traumatic stress, historical trauma, and associated interventions for clients from marginalized communities. 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Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"74763",title:"An Urban Paradox: Urban Resilience or Human Needs",doi:"10.5772/intechopen.95271",slug:"an-urban-paradox-urban-resilience-or-human-needs",body:'\nLandscapes have affected by climate changes, land use changes and human-based complexities; and the mosaic structure within the landscape can change. All these changes can occured in different spatial dimensions and frequencies [1]. Changes in land use patterns play an important role especially in the growth of urban areas and in the transformation of land use patterns in rural or urban areas. In addition, important ecosystems such as agricultural areas, forests, coastal dunes and wetlands are the first and most adversely affected by this change [2, 3, 4, 5]. However, these ecosystems are the most important areas that ensure the life cycle of cities and the resilience of cities.
\nWithin used to create resistance against disaster such as flood, climate change and etc., the concept of resilience takes on the meanings of adaptation, change and transformation when it is used in relation to many different problems in the urban area.
\nUNISDR (2009) defines resilience as: “The ability of a system, community or society exposed to hazards to resist, absorb, accommodate to and recover from the effects of a hazard in a timely and efficient manner, including through the preservation and restoration of its essential basic structures and functions [6].”
\nUrban resilience consists on the capacity of a city and its urban systems to absorb the first damages, reduce the impacts arising from. Also, urban resilience, considering all kinds of disasters and disruptions in the systems of a city, is important to make communities more resilient when facing extreme events [7].
\nUrban resilience refers to the ability of an urban system-and all its constituent socio-ecological and socio-technical networks acrosstemporal and spatial scales-to maintain or rapidly return to desiredfunctions in the face of a disturbance, to adapt to change, and toquickly transform systems that limit current or future adaptivecapacity In this definition, urban resilience is dynamic and offers multiple pathways to resilience (e.g., persistence, transition, and trans-formation). It recognizes the importance of temporal scale, and advocates general adaptability rather than specific adaptedness. The urban system is conceptualized as complex and adaptive, andit is composed of socio-ecological and socio-technical networks that extend across multiple spatial scales [8]. As the concept of life has rich connotations and denotations that involve social, economic and ecological dimensions, along with multilevel interactions between human beings and the environment, the contradiction between supply and demand in daily life, as a collection of multiple pressures and even risks of socio-ecological systems, is an urgent problem of urban resilience [9].
\nResilience in terms of cities generally refers to the ability to absorb, adapt and respond to changes in an urban system [10].
\nUrban systems’ are conceptualized as complex, adaptive, emergent ecosystems composed of four subsystems; governance networks, networked material and energy flows, urban infrastructure and form, and socioeconomic dynamics that themselves are multi-scalar, networked and often strongly coupled [8].
\nThe main common point of these definitions is that resilience is a way to improve a strategy/behavior to be able to survive and to adapt against external shifts/impacts. Basically, to construct resilience, the main ingredients are: resource, latitude (redundancy), networks (social and institutional), information, experience, knowledge, diversity and robustness [11].
\nWith the concept of urban resilience, instead of returning to a stable balance point again, it would be more appropriate to talk about a new structure that understands and adapts to the change and transformation that occurs with different effects. In addition to the built environment, the harmony, learning, change and transformation of social structures stand out according to urban problems.
\nResilience is not a characteristic that is evenly spread through the urban population. It depends crucially on the socially differentiated capacities of different groups and individuals. Poverty, gender, ethnicity and age have all been documented as contributing to differential vulnerability of social groups in cities to hazards like climate change, earthquake, flood, aridity, through features such as the quality of housing, location and access to services or social networks [12, 13, 14, 15].
\nAccording to Biggs et al. [19], resilience as the capacity of a social-ecological system to sustain human well-being in the face of change, by persisting and adapting or transforming in response to change. A central challenge in this context is the capacity of social-ecological systems to continue providing key ecosystem services that underpin human well-being in the face of unexpected shocks as well as gradual, ongoing change [16, 17, 18, 19].
\nThe science of resilience helps deal with the uncertainties that arise from changes in land cover involving the interactions between environmental, social, and economic ecosystems within a city [20, 21].
\nIn this context, it can be said that the change, transformation and adaptation expected to be achieved with the concept of urban resilience cannot be considered separate from human and human welfare. Although the human beings make the policies and their implementations to ensure urban resilience, the human causes the cities to be in this situation despite these policies. Then it is possible to ask the questions “resilience for whom?” and resillence or human needs.
\nThe research area is located within the borders of Sarıyer in Istanbul. Zekeriyaköy, one of the oldest villages of Sarıyer is close to Maden, Bahçeköy, Uskumruköy, Demirciköy and Rumeli Feneri.
\n1.5% of the Zekeriyaköy-Uskumruköy Region is in the first degree archeological site, 5% is in the second degree archeological site and 93.5% is in the third archeological site.
\nZekeriyaköy-Uskumruköy settlements are located in the north of the Istanbul and should be protected with their existing natural values. The region is in the interaction of forest and Bosphorus back view and it has a special position in terms of uses around it (\nFigure 1\n) [22].
\nLocation of Zekeriyaköy [
According to the 2019 Address Based Population Registration System (ABPRS) data, the population of Sarıyer District is 342,503 (https://www.nufusu.com/ilce/sariyer_istanbul-nufusu). Zekeriyaköy, which was a forest village until 2012, has started to be a neighborhood. The population in Zekeriyaköy is 18.707 in 2018 [25] (\nTable 1\n).
\nYear | \n2000 | \n2007 | \n2008 | \n2009 | \n2010 | \n2011 | \n2012 | \n2013 | \n2014 | \n2015 | \n2016 | \n2017 | \n2018 | \n2019 | \n
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Population | \n7323 | \n8230 | \n11,279 | \n12,528 | \n13,817 | \n14,755 | \n15,750 | \n16,524 | \n17,581 | \n18,457 | \n18,833 | \n18,867 | \n18,707 | \n19,896 | \n
Zekeriyaköy Population for the last 19 years.
There is a rapid increase in the population development of the settlements in the adjacent area of Sarıyer District between 1995 and 1997 and 1997-2000 (\nFigure 2\n). Especially after the earthquake of 17 August 1999 (due to the solid ground of the settlement, infrastructure and ease of transportation), it has been used as the first residential area by the upper income group.
\nPopulation of Zekeriyaköy by Years.
As a result of the great wave of immigration caused by the war during the 93 War, several families from Caucasus and Crimea were settled in Zekeriyaköy. In addition to this, migrations have been received from the Black Sea Region [26].
\nUntil the 1980s, it looked like a village and recreation area consisting of 70 houses with 2 floors and a garden but especially since 1987, it has gone through a period of radical change. While Zekeriyakoy began to change rapidly since the 1990s, it became an important center of attraction as a result of the solid ground of the Sarıyer region and the naturalness of the village, especially after the Marmara Earthquake of 1999. The area has turned into a region close to the city center because of the high income group who prefer a quiet environment and expensive villas [22].
\nIn Zekeriyakoy, old residents and new comers live together. These different groups create a multicultural but less interactive social structure. New arrivals in the region are representatives of a different culture with their educational level, professional and economic accumulation, while the inhabitants of the old villages are people engaged in animal husbandry and agriculture, producing according to feudal society characteristics [27].
\nIn this study, it is aimed to reveal the landscape changes between 2000 and 2019 in Zekeriyakoy. Corine Land cover and Google satellite data have been used to detect changes in the research. Using the Quantum GIS program for transportation lines, the transportation routes have been taken from the data provided by Open Street Map and transferred to ArcGIS environment.
\nCorine Land Cover data have been used to determine the land changes for the years 2000 - 2006 – 2012 – 2018 and 2019. Corine (Coordination of Information on the Environment) is the land cover/use data generated by computer aided visual interpretation method based on satellite imagery according to the Land Cover/Use Classification set by the European Environment Agency. In the Corine Land Cover, the artificial zones are classified as urban spot areas in the study under the categories 111 and 112 under the urban structure classification and the construction sites under code 133 under the artificial sites. The areas coded with 211 and 222 in the agricultural areas in the section of Corine land cover have been classified as agricultural areas within the scope of the study and the areas coded with 311, 312, 333 in the forest and semi-natural areas have been classified as forest areas. In 2015, Google satellite photo ArcGIS 10 program coordinates the agricultural areas, forest areas and urban stain areas manually. The maps obtained between 2000 and 2019 have overlapped and Spatial Difference and Spatial Intersection analyzes have been performed in GIS environment and physical changes of landscapes have been determined quantitatively and graphs have been created. Density analysis was performed by determining the density of the buildings according to years with the Spatial Analysis Tools - Kender Density in the ARCGIS program.
\nWithin the scope of this study, the land use data for Zekeriyaköy for the years 2000-2019 have been generated. In this study conducted to determine the changes between 2000, 2006, 2012, 2018 and 2019, it is seen that forest areas occupy the largest area.
\nAccording to the study in 2000, urban stain areas are 330.6 ha, agricultural areas are 161.4 ha and forest areas are 587.6 ha (\nFigures 3\n and \n4\n). According to this, forest areas constitute the highest area with 54% in the spatial distribution, while urban areas constitute 31% and agricultural areas constitute 15% (\nFigure 4\n).
\nLand use map in 2000.
Distribution of land use in 2000.
According to the study in 2006, forest areas are 558.4 ha, urban strain areas are 378.1 ha and agricultural areas are 143.1 ha (\nFigures 5\n and \n6\n). According to this, forest areas constitute the highest area with 52% in the spatial distribution, while urban areas constitute 35% and agricultural areas constitute 13%.
\nLand use map in 2006.
Distribution of land use in 2006.
According to the study in 2012, urban areas are 423.4 ha, agricultural areas are 97.7 ha and forest areas are 558.5 ha (\nFigures 7\n and \n8\n).
\nAccording to this, forest areas constitute the highest area with 52% in the spatial distribution, while urban areas constitute 39% and agricultural areas constitute 9%.
\nLand use map in 2012.
Distribution of land use in 2012.
According to study in 2018, urban areas are 456 ha, agricultural areas are 97.7 have forest areas are 525.9 ha (\nFigures 9\n and \n10\n). According to this, forest areas constitute the highest area with %48,7 in the spatial distribution, while urban areas constitute % 42,23 and agricultural areas constitute %9,05.
\nLand use map in 2018.
Distribution of land use in 2018.
According to the study in 2019, urban areas are 478.1 ha, agricultural areas are 72 ha and forest areas are 529.5 ha (\nFigures 11\n and \n12\n).
\nAccording to this, forest areas constitute the highest area with 49% in the spatial distribution, while urban areas constitute 44% and agricultural areas constitute 7%.
\nLand use map in 2019.
Distribution of land use in 2019.
The changes and regional spreads over the years enable projections about the future of that region. Analyzing, understanding and managing the changes both physical and social are necessary in order to protect and ensure the continuity of areas such as wetlands, agricultural areas, forest areas that have special importance in ensuring urban resilience.
\nDetermination of landscape change, it provides the relationship between landscape structure and process. Any change that will occur will affect the landscape structure and will lead to changes in living environments and to a large extent shrink.
\nZekeriyakoy, when it was a village until the 1980s, has been in the process of a radical change especially since 1987 and it has become an important center of attraction especially after the Marmara Earthquake in 1999. Together with the physical change, the greatest change has been experienced in the social structure. The area has become a region where there are sites with expensive villas and preferred by the residents in high-income group who prefer close to the city center and a quiet environment. The earthquake in 1999 played a major role in this change, which has been observed since 2000. Single-storey or 2-storey villas and sites on solid ground have become an attractive living space for high-income groups. Thus, there has been a major change in the socio-economic structure of Zekeriyaköy.
\nZekeriyaköy, which entered the rapid urbanization process due to its proximity to the city center and ease of transportation, suffered significant losses in forest and agricultural lands during this period. In particular, urban stains such as residential areas were created instead of agricultural land, and thus a large part of fertile agricultural land became unusable. In approximately 20 years, 89.4 hectares of agriculture and 58.1 hectares of forest area have been lost. The majority of these areas have turned into independent villas and closed sites.
\nThere is a significant amount of change between the years 2000-2019. It is observed that forest areas remain the largest area in this 20-year period of change, while serious reductions are experienced (\nTable 2\n).
\nYears | \nUrban fabric (ha) | \nAgriculturel area (ha) | \nForests area (ha) | \nTotal (ha) | \n
---|---|---|---|---|
2000 | \n330,6 | \n161,4 | \n587,6 | \n1079,6 | \n
2006 | \n378,1 | \n143,1 | \n558,4 | \n1079,6 | \n
2012 | \n423,4 | \n97,7 | \n558,5 | \n1079,6 | \n
2018 | \n456 | \n97,7 | \n525,9 | \n1079,6 | \n
2019 | \n478,1 | \n72 | \n529,5 | \n1079,6 | \n
Land cover amounts between 2000 and 2019.
Between 2000 and 2019, the greatest spatial change in landscape changes in Zekeriyaköy occurred in urban stain areas. Urban stain areas increased by 47.5 ha between 2000 and 2016 and the change rate was 14.37%. Between 2006 and 2012, it increased by 45,3 ha and the change rate was 11,98%. Between 2012 and 2018, urban strain area is 32,6 ha and the change rate is 7,69%. Between 2018 and 2019, urban strain area is 22,1 ha and the change rate is 4,85%.
\nBetween 2000 and 2012, agricultural land decreased. The majority of urban stains were spread in agricultural areas. The greatest change in the agricultural fields was experienced between 2006 and 2012. Between 2006 and 2012, agricultural land decreased as 45.4 ha (\nTable 3\n) (\nFigure 13\n).
\nClass | \nYears | \nAmount of change | \nIncrease/decrease | \nChange rate | \n
---|---|---|---|---|
Urban fabric | \n2000-2006 | \n47,5 | \n↑ | \n14,37% | \n
2006-2012 | \n45,3 | \n↑ | \n11,98% | \n|
2012-2018 | \n32,6 | \n↑ | \n7,69% | \n|
\n | 2018-2019 | \n22,1 | \n↑ | \n4,85% | \n
Agricultural area | \n2000-2006 | \n18,3 | \n↓ | \n11,33% | \n
2006-2012 | \n45,4 | \n↓ | \n31,73% | \n|
2012-2018 | \n0 | \n— | \n0% | \n|
\n | 2018-2019 | \n25,7 | \n↓ | \n26,31% | \n
Forest area | \n2000-2006 | \n29,2 | \n↓ | \n4,97% | \n
2006-2012 | \n0,1 | \n↑ | \n0,01% | \n|
2012-2018 | \n32,6 | \n↓ | \n5,19% | \n|
\n | 2018-2019 | \n0 | \n— | \n0% | \n
Area change rates between 2000 and 2019.
Distribution of land uses of Zekeriyaköy.
As a result of the studies, urban stains have increased in the last 19 years in Zekeriyaköy as 147.5 ha. 89.4 hectares of this increase was due to the decrease of 58.1 hectares of forest area.
\nIn addition, it is observed that this serious increase in housing problem is very intense in certain regions, but there is a serious risk of spreading to the whole region (\nFigure 14\n).
\nDistribution of density of urban fabric in Zekeriyaköy in the last 19 years.
This study is important in terms of how the field has changed in 20 years and the problems that this change will cause for the future. It is possible to control the urbanization pressure on the villages close to cities and to protect the identity of the villages or to protect them together with natural landscape areas and to plan them with an integrated approach.
\nThe importance of forest areas and agricultural areas was further understood during the Covid 19 pandemic process. These areas will ensure the resistance of cities to disasters. The study area became an escape area after a major earthquake in Istanbul. However, if the development and population increase continue in the region, the loss of forest and agricultural areas will continue rapidly.
\nOne of the biggest problems of today is the increasing urban population and it has spread metropolises and the surrounding villages, rural areas and cities. Although it is known that agriculture is the struggle to save our future today, agricultural areas are rapidly being transformed into structured areas.
\nIt is necessary to look for answers to questions about who is responsible for this situation or how it can be prevented. Of course, whoever is responsible are not urban people who moved to a safer area after a disaster. The main problem is that the urban does not have a functioning plan and cannot be protected. Nowadays, pandemic and disasters caused by climate change require the preparation and implementation of an emergency action plan. In addition, citizens should be informed about the importance of natural resources such as agricultural areas, forest areas and water resources. The future of the city and its citizen depends on the protection of natural resources and this conservation awareness should be created. It should not be forgotten that the most important need of human is shelter, nutriment and water. This will only be possible by preserving the balance of nature and natural resources.
\nMud beds, typically found at the bottom of rivers, lakes and in coastal areas, belong to the category of cohesive material. These deposits consist of water, clay minerals, sand, silt and organic matter (such as living microorganisms and in particular their excreted biopolymers) [1]. These mud beds are usually exposed to a continuous wave motion and disturbances produced by ship movement [1, 2], human actions such as dredging [3], natural climatic events and bioturbation [4]. The water column can be divided into different layers. In its large upper part, where mud particles are advected by currents and diffused by turbulent motion, mud is found as suspended particulate matter (SPM). Close to the bottom, different mud layers are found with increasing density as function of depth. These layers are defined as fluid mud (FM), pre-consolidated sediment (PS) and consolidated sediment (CS). Besides having different densities, these mud layers are known to have significantly different compositions and rheological fingerprints.
Fluid mud, the most important mud layer from a navigational perspective, is typically identified as a layer with a density of 1030–1300 kg m−3, whereby hindered settling of particles plays a role due to the presence of flocs (i.e., combination of clay particles and organic matter) [5, 6, 7]. All mud layers, but particularly the fluid mud layer, display complex rheological behavior, i.e., combination of thixotropy, shear-thinning, two-step yielding behavior and viscoelasticity [8, 9]. The rheological/cohesive properties of mud are observed to vary as a function of solid fraction (or bulk density), type and concentration of organic matter, type of clay minerals and ionic concentration [10, 11, 12, 13, 14, 15, 16, 17]. The thorough understanding of the rheological characteristics of mud, as a function of above-mentioned parameters, can help to estimate the strength, the flow and thickness of (fluid) mud in ports and waterways. The quantification of the rheological properties for fluid mud also facilitates the definition of boundary conditions for sediment transport modeling, which in turn helps optimizing the dredging operations and defining the proper maintenance strategy for navigational channels [18, 19, 20, 21]. However, in order to develop the appropriate in-situ techniques for measuring rheological properties, these characteristics need to be analyzed in laboratory beforehand. Therefore, in this chapter, following research questions are answered: How to efficiently collect the “undisturbed” mud sample? Which sediment properties are important for determining the rheological properties of mud? Which protocols are suitable for measuring rheological characteristics, i.e., yield stress of mud? Which empirical or semi-empirical model is appropriate to fit the rheological experimental data of mud, particularly for two-step yielding? How much comparable is the rheological signature of mud samples from different sources?
In this chapter, two different sampling techniques are presented to collect the “undisturbed” mud samples along with their important physical properties (Section 2). In Section 3, different protocols used to measure the rheological properties particularly yield stresses of mud are detailed and compared. Furthermore, the empirical or semi-empirical models that are commonly used to fit the rheological experimental data of mud are presented in Section 4. The influence of different factors such as density and organic matter content on the rheological behavior of mud is discussed in Section 5. In the end, the rheological properties, i.e., yield stress, of mud samples obtained from different ports are compared. In the present chapter, only laboratory experiments are presented.
In order to determine the physical and rheological characteristics of mud in the laboratory, appropriate sampling method needs to be applied. Two of the most commonly used sampling methods/equipment for mud are: (i) Van Veen grab sampler, and (ii) Frahmlot core sampler (see Figure 1). The criterion for selecting the suitable sampling method is based on the fact that the mud should be obtained in an “undisturbed” state with a naturally occurring density gradient profile, in order to estimate the properties of mud as close as possible to in-situ conditions. Core sampler is considered to meet this criterion well. Apart from collecting in-situ mud layers with different densities, another approach to study the effect of density on the rheological behavior is to dilute a consolidated mud layer, to obtain different samples with varying densities [9, 23]. However, the rheological characteristics of natural and diluted mud layers of same density are found to vary significantly from each other [24].
(a) Van Veen grab sampler and (b) Frahmlot core sampler [
The bulk density (or water content) of the mud samples is usually estimated using the oven-drying method [25, 26, 27, 28]. In short, the weight of the sample is recorded before and after heating at 105°C for 24 h. Using these weights and the density of water and minerals (i.e., 1000 and 2650 kg m−3, respectively), the mean bulk density of the sample is obtained. The particle size distribution (PSD) of mud is typically investigated using (static) light scattering methods [17, 28, 29]. However, this technique also possesses some inherent drawbacks which are the facts that (i) the conversion between raw data and particle size is based on the assumption that the particles are spherical and have a homogeneous composition, (ii) the measurements are possible in a limited range of concentrations, and (iii) there can be a serious overestimation of the amount of large particles due to the mathematical smoothing of the PSD’s by the manufacturer’s software [30]. The total organic carbon (TOC) of mud samples is commonly analyzed by using loss-on-ignition method [31, 32], which is based on weighing the sample before and after heating at 430–500°C for 24 h. The total organic carbon is then estimated by loss in weight. All these sediment properties are known to significantly influence the rheological characteristics of mud samples.
Mud can either behave as a solid-like material (i.e., elastic solid) at small stresses or as a liquid-like material above a critical value of stress, defined as yield stress. The nautical bottom for ports and waterways is typically defined on the basis of mud density [33], which does not account for the solid/liquid transition defined by the yield stress. Measurement of the yield stress of mud is, therefore, quite useful in defining the navigability of mud layers [15, 21]. The determination of yield stress is highly dependent on the selected rheological geometry and experimental method, as significantly different yield stress values can be obtained due to (i) the history of samples before analysis, (ii) differences in experimental methods, (iii) the use of different criteria for defining the yield point, (iv) different experimental timescales [34, 35, 36, 37, 38, 39].
Several rheological geometries are available to perform the rheological analysis of mud including concentric cylinder (Couette), cone & plate (CP), parallel plate (PP) and vane. Cone & plate geometry has been observed to produce scattered rheological responses for mud samples due to the presence of large particles within the narrow gap between cone and plate and, hence, is not recommended for this kind of samples [40]. The remaining geometries can be used for analyzing mud samples but with certain benefits and limitations for each one. The differences between the geometries is illustrated in Figure 2a which shows the response of a FM mud layer in terms of elastic stress (
(a) Elastic stress as a function of amplitude at 1 Hz using different geometries for FM layer obtained from Port of Hamburg. Solid line is just a guide for the eye. Bars represent standard deviation. Circles with dashed lines represent the static yield points (SYS) and circles with solid lines represent the fluidic yield points (FYS). (b) Static and fluidic yield stress values obtained from elastic stress method for different mud layers collected from Port of Hamburg using Couette, parallel plate and vane geometries. Reprinted from Ref. [
Figure 2b presents the yield stress values of different mud layers obtained by using the elastic stress method for different geometries. The results show that the highest yield stress values are obtained for parallel plate geometry, which may be attributed to the fact that this geometry induces the lowest disturbance in the sample while the plates are approached to confine the sample. However, this geometry is not very appropriate for analyzing the rheology of liquid-like samples, as the sample can flow out of the holder during shearing. Couette geometry is most suitable to analyze the rheological characteristics of mud ranging from very fluid to paste-like. For consolidated samples, however, it is preferable to use vane geometry, as the bob used in Couette geometry usually gets stuck during analysis of (very) dense mud samples.
In addition to different geometries, several rheological protocols have been reported in literature to determine the yield stress of mud. These protocols include shear rate ramp-up [29, 44], shear stress ramp-up [15, 17], and Claeys et al. protocol [45]. Shear rate/shear stress ramp-up methods are quite fast and easy to perform. On the other hand, Claeys et al. protocol is based on several cycles of selected shear rates (applying a shear, stop shearing, applying a shear…) along with high shear rate steps in-between these cycles, with a total experimental time of about 15–20 min. Figure 3 shows the pictorial representation of different experimental protocols that can be used to measure the yield stresses of mud.
Pictorial representation of the protocols (a) stress ramp-up, (b) Claeys et al. protocol, (c) increasing equilibrium flow curve (EFC), (d) decreasing equilibrium flow curve (EFC), (e) shear rate ramp up and ramp down (CSRT) and (f) pre-shear test. Reprinted from Ref. [
The outcome of the different protocols in terms of shear stress as a function of shear rate or apparent viscosity as a function of shear stress for Port of Hamburg mud is shown in Figure 4. The values of yield stresses (static and fluidic) obtained from the viscosity declines of these curves (see Figure 4b) are presented in Table 1. It can be seen from Table 1 that higher yield stress values are obtained from stress ramp-up test, ramp-up step of shear rate ramp up and ramp down (CSRT) test and increasing equilibrium flow curve (EFC) test. This is linked to the fact that these methods deform mud samples from an almost undisturbed state to an almost fully disturbed state. These methods are, therefore, suitable to measure the yield stresses of mud close to in-situ conditions. However, the determination of a static yield point is somehow difficult in case of ramp-up step of CSRT test (due to the scattering of the initial apparent viscosity as function of stress points, see black curve in Figure 4b) and increasing EFC test is a somehow lengthy test (
(a) Shear stress as a function of shear rate and (b) apparent viscosity as a function of shear stress for mud sample collected from port of Hamburg using Couette geometry; solid symbols in CSRT protocol represent the ramp-up and the empty symbols represent the ramp-down; solid lines are just the guide for the eye. Reprinted from Ref. [
Method | Static Yield Stress (Pa) | Fluidic Yield Stress (Pa) |
---|---|---|
Claeys protocol | 3.1–4.4 | 26 |
CSRT-ramp up | 9.0–12.3 | 40 |
CSRT-ramp down | 7.6 | 29 |
EFC-decreasing | 5.2 | 26 |
EFC-increasing | 7.1 | 38 |
Pre-shear | 7.1 | 27 |
Stress ramp-up | 11 | 40 |
Static and fluidic yield stress values of mud sample from port of Hamburg obtained from viscosity declines with Couette geometry for different protocols.
In literature, several terminologies have been used to represent the two yield points for mud. The correspondence between these terminologies is presented in Table 2.
Shakeel et al. [17] | Toorman [47] | Toorman [48] | Wurpts & Torn [15] | Claeys et al. [45] |
---|---|---|---|---|
Fluidic yield stress | Static yield stress | Criterion for navigation | Undrained shear strength | |
ΔYS = (Fluidic ̶ Static) | Bingham yield stress | Dynamic yield stress | Bingham yield stress | |
Static yield stress | (True) yield stress | Yield stress |
Correspondence between different yield stress terminologies reported in literature for mud.
Thixotropy, a commonly observed rheological fingerprint of suspensions, is defined as a phenomenon in which the viscosity of the system is both shear rate and time dependent. Therefore, a thixotropic material shows a time dependent viscosity (decreasing as a function of time; when the viscosity is increasing as a function of time the material is said to be rheopectic) after applying/stopping shear rate [49]. Typically, the thixotropic behavior of mud is determined by performing a shear rate ramp-up followed by a constant high shear step and then a shear rate ramp-down step [17, 44]. The area of the hysteresis loop formed between the upward and downward curve quantifies the thixotropic behavior of the material [50]. Multiple thixotropic loops can also be produced for the same sample without allowing for any delay between each loop, in order to understand the thixotropic behavior of mud after extensive structural breakdown [17].
In addition to thixotropy, the structural recovery of mud after extensive shearing is also interesting to analyze by using small amplitude oscillatory rheological measurements. A three step experimental protocol has been reported in literature to quantify the structural recovery of mud after steady pre-shearing [51]. In short, the first step of the protocol involves the application of an oscillatory amplitude within the linear viscoelastic (LVE) regime and recording the moduli as a function of time (i.e., resting step). This step provides the initial moduli values before the pre-shearing step and also eliminates the disturbances created by the geometry. In a second step, a constant high shear rate is applied for a time interval which is enough to completely destroy the structure of the sample (i.e., pre-shear step). The last step provides the key information about the structural recovery of mud after pre-shearing, again by applying the oscillatory amplitude within LVE regime and recording the moduli as a function of time (i.e., structural recovery step). The schematic representation of the experimental protocol is shown in Figure 5.
Schematics of the experimental protocol employed for the structural breakup and recovery in mud samples. Reprinted from Ref. [
Apart from above mentioned rheological properties of mud, the estimation of moduli (storage and loss) within LVE regime (i.e., without significantly affecting the structure of the material) as a function of frequency provides useful information about the strength of the material. Preliminary oscillatory amplitude sweep experiments are usually performed to determine the LVE regime (where the response of material is independent of applied stress/strain). The frequency sweep tests are then performed by selecting the appropriate amplitude of oscillation within LVE regime and the desired frequency range [17, 29]. The results can either be plotted as moduli (storage and loss) vs. frequency or complex modulus and phase angle as a function of frequency. In addition to small amplitude oscillatory experiments, large amplitude oscillatory tests have also been reported in literature to analyze the nonlinear response of mud in terms of stress waveform and Lissajous pattern [41].
In literature, the rheological behavior (i.e., flow curve) of mud has been fitted with numerous empirical or semi-empirical models including Bingham [52], Herschel-Bulkley [53], Worrall-Tuliani [54], and Toorman model [48], given as follows:
Bingham model:
Herschel-Bulkley model:
Worrall-Tuliani model:
Toorman model:
where
It has been reported in literature that mud samples usually exhibit a two-step yielding phenomenon [17, 41, 51], which is associated with two yield stresses. These two yield points depict the transition between a fully structured sample (i.e., interconnected network of flocs), partially structured sample (i.e., mobile flocs) and almost fully disturbed sample (i.e., smaller flocs or particles). Therefore, the shear stress as a function of shear rate for the whole investigated range can be written as a sum of two functions, which represent the two yield regions, given as:
where
where
The shear stress
The shear stress
Shear stress as a function of shear rate for mud sample from port of Hamburg obtained by performing stress ramp-up test using Couette geometry. The solid line represents the two-step yielding model fitting
The experimental data of structural recovery tests (i.e., storage modulus as a function of time) can be easily fitted with the stretched exponential function [51] given as follows:
where
Density (i.e., solid content and water content) is an important characteristic of mud which can significantly affect their rheological behavior, such as yield stress, thixotropy and moduli. In natural environment, the density gradient in mud is usually created by wave motion or human activities along with settling of particles. In literature, several researchers have reported the rheological characteristics of mud as a function of solid content or density [9, 17, 23, 26, 27, 29, 55]. For instance, the mud obtained from Lianyungang, China showed an exponential increase in yield stress as a function of volume concentration of particles [29]. Likewise, the similar exponential relation between yield stress and solid content or water content of mud has also been reported by other researchers for samples obtained from different ports [17, 26, 27, 55].
However, this correlation between yield stress and density is highly dependent on the mud composition. For example, the (fluidic) yield stress values as a function of density for mud samples collected from different locations of port of Hamburg is shown in Figure 7a. It can be seen that the dependence of yield stress on mud density is significantly different for the samples collected at different locations. In order to further quantify this difference, both the fitting parameter ‘a’ for the power law relation given in the caption of Figure 7a and the total organic carbon (TOC) are plotted as function of different locations (Figure 7b). There is clearly a correlation between the TOC content and the fitting parameter ‘a’. This behavior suggests that the yield stress of mud is strongly dependent both on TOC and mud density, as already reported in literature [15, 16].
(a) Fluidic yield stress (
Several researchers have reported the rheological characteristics of mud as a function of density either by collecting natural mud layers with varying density [17] or by diluting dense mud samples [9, 23]. However, it has been observed that the natural and diluted mud layers display significantly different rheological properties [24] (see Figure 8), which may again be linked to the composition of each mud layer, procedure of dilution, etc.
Fluidic yield stress values vs. bulk density for natural and diluted mud layers from Port of Hamburg. Solid lines represent the power law fitting. Reprinted from Ref. [
Apart from yield stress, other rheological properties including moduli, thixotropy, structural recovery, etc. are also strongly dependent on the density of mud samples [24, 51]. For instance, the structural recovery, observed by using above mentioned protocol (Section 3.2), for mud samples collected from different locations and different depths is shown in Figure 9a and b, respectively. From the figure, it is found that the structural recovery (i.e., moduli values) of mud is highly dependent on the mud layer, and position in the harbor [51]. Hence, density of mud is a critical parameter particularly for describing their rheological characteristics, however, for defining nautical bottom in ports only density is not enough and other parameters also need attention from the researchers.
(a) Normalized storage modulus (
The presence of organic matter in mud usually hinders the settling of particles and can help to form fluid mud layers, in addition to the natural wave motion or human activities which are also responsible for the existence of these layers. This organic matter can or cannot be mineral-associated organic matter (i.e., organic matter adsorbed at the mineral surface or trapped inside the particle) [56]. There are two common sources of organic matter in mud: (i) natural and (ii) anthropogenic. The natural sources include erosion of terrestrial topsoils, plant litter, planktonic and pelagic biomass while surface runoff and sewage waste contribute to the anthropogenic source of organic matter [32].
The existence of organic matter in mud is also known to significantly influence the rheological and cohesive properties of mud [10, 14, 15]. For instance, the rheological characteristics of mud have been investigated in literature by varying organic matter content and keeping density constant [16]. The results showed an increase in yield stresses and moduli of mud with increasing organic matter content, for a similar density value (see Figure 10a). However, further research is required to investigate the effect of type of organic matter/biopolymer at different pH or ionic concentrations on the rheological behavior of mud.
(a) Yield stress values and complex modulus at 1 Hz for mud samples having similar density (1210 kg. M−3) and different organic matter content obtained from port of Hamburg, adapted from ref. [
In addition to organic matter content, its extent of degradation can also significantly affect the rheological properties of mud. Aerobic degradation (in the presence of oxygen) of organic matter usually results in the production of carbon dioxide while anaerobic degradation produces methane in addition to carbon dioxide [32]. For a detailed information about the aerobic and anaerobic degradation of mud, see ref. [32]. The entrapped gas bubbles of methane can significantly decrease the density and strength of mud, due to the poor solubility of methane in water. The outcome of stress ramp-up tests for fresh and anaerobically degraded mud samples, collected from port of Hamburg, is shown in Figure 10b. It can be seen that the values of the two yield stresses (static and fluidic) for degraded sample are significantly lower than the fresh ones. However, further quantification of organic matter content before and after degradation is required, in order to correlate the organic matter degradation with rheological characteristics of mud.
The yield stress dependency on mud density is observed to vary for the samples collected from different parts of the world. As an example, fluidic yield stress values are plotted as a function of density for the samples collected from different ports (see Figure 11). One observes that the mud samples obtained from different ports exhibit considerably different yield stress values for a particular density. This difference may be attributed to the composition of mud, particle size distribution, type and content of TOC, ionic strength, etc. This behavior highlights the needs for a systematic investigation of the rheological properties of mud, as function of relevant parameters, for different ports.
Fluidic yield stress as a function of excess density (
Furthermore, the values of the rheological characteristics including yield stress and storage modulus of mud samples collected from different parts of the world are compared in Table 3. It can be seen that the mud from the Port of Santos [27], the Hangzhou Bay, China [23], the Port of Rotterdam [9], and the Port of Hamburg [16] display similar values of rheological properties for similar densities. However, the mud samples obtained from Mouth of Yangtze River, Shoal of Hangzhou Bay, and Yangcheng Lake, China [44] possess higher values of rheological parameters, which may be attributed to the their higher densities. Moreover, the mud from Eckernförde Bay, Germany show considerably lower yield stress values for the comparable densities, which may be linked to the organic matter content or measuring protocol.
Location | Bulk Density (kg/m3) | Fluidic Yield Stress (Pa) | Storage Modulus @ 1 Hz (Pa) | Ref. |
---|---|---|---|---|
Port of Rotterdam, the Netherlands | 1168 | 7 | 45 | [9] |
Eckernförde Bay, Germany | 1038–1280 | 1.07–20.50 | — | [31] |
Hangzhou Bay, China | 1145–1634 | 0.55–40 | 0.02–15 | [23] |
Mouth of Yangtze River, China | 1650–1700 | 910–2810 | — | [44] |
Shoal of Hangzhou Bay, China | 1705–1741 | 772–2140 | — | [44] |
Yangcheng Lake, China | 1651–1691 | 2070–3960 | — | [44] |
Lianyungang Port, China | 1098–1305 | 0.098–28.029 | 2–1050 | [29] |
Port of Santos, Brazil | 1085–1206 | 5–334 | — | [27] |
Port of Rio Grande, Brazil | 1132–1308 | 5–350 | — | [27] |
Port of Itajaí, Brazil | 1138–1360 | 5–299 | — | [27] |
Amazon South Channel | 1293–1512 | 5–379 | [27] | |
Port of Hamburg, Germany | 1087–1210 | 2.44–312 | 0.47–7915 | [16] |
Comparison of rheological properties (i.e., yield stress and storage modulus) of mud samples obtained from different sources.
As already mentioned that the yield stress can be used as a criterion to define navigable fluid mud layers, Port of Emden, Germany is reported to use the yield stress of 100 Pa as a criterion for nautical bottom [15]. However, this critical value of yield stress for defining nautical bottom is significantly dependent on the spatial variation of the sediment characteristics (i.e., sand content, organic matter content, etc.). For instance, the rheological properties of mud samples from Port of Hamburg, Germany are significantly different for different locations within the port, due to the different organic matter content [46]. Therefore, using a single value of yield stress as a criterion for defining nautical bottom for the whole port can be quite tricky and instead, different boundaries of yield stress as a function of density can be used for different locations, in order to define the nautical bottom.
In this chapter the rheological behavior of mud as found in harbors, is discussed. Different mud layers, formed as a result of either natural or human activities, were defined. These mud layers exhibit a complex rheological fingerprint, by displaying a combination of thixotropy, two-step yielding behavior and viscoelasticity, which is conventionally associated to the existence of clay flocs (aggregated clay particles with organic matter). The analysis of the rheological properties of the top layer (fluid mud layer) is crucial for navigational purposes, optimizing dredging operations and the proper maintenance of dredged navigational channels.
In order to study the rheology of mud in laboratory, it was found that core sampling is the best sampling technique as it allows to collect mud samples without much disturbance. In contrast to what some authors do, it is not recommended to dilute a specific sample to predict its rheological behavior as function of density. It is shown that the rheological properties of natural mud layers of different densities found on top of each other at a specific location in the harbor do not match the properties of samples obtained from diluting the densest (deepest) mud layer sample. The reason lays in the differences in mud composition and structure at different depths.
The determination of yield stress of mud is highly dependent on the selected rheological geometry and experimental method. A detailed analysis shows that the Couette geometry along with stress ramp-up test is the most suitable combination to analyze the yield stress of mud for ports and waterways applications. The optimization of this stress ramp-up test enables to reduce the experimental time for different mud layers (∼ 10–200 s). Several empirical or semi-empirical models are available in literature to fit the experimental data of mud displaying a single-step yielding. However, the mud samples are observed to exhibit a two-step yielding and, therefore, the behavior of shear stress as a function of shear rate (i.e., flow curve) can be represented as a sum of two functions, which capture the two yield regions. The model captures the two-step yielding phenomenon in mud samples quite well, within the density range of 1050–1200 kg. m−3.
Several factors are known to influence the rheological characteristics of mud such as density and organic matter content. An exponential relation between yield stress and density (i.e., solid content) is usually observed in literature for mud from different sources. However, this correlation between yield stress and density is highly dependent on the mud composition. Apart from yield stress, other rheological properties including moduli, thixotropy, structural recovery, etc. are also strongly dependent on the density and composition of mud samples. For instance, the fluidic yield stress of mud from Port of Hamburg, Germany is observed to increase from 79 Pa to 312 Pa by increasing the organic matter content from 2.8% to 4.3%. The degradation of organic matter in mud, which can occur over time for different layers is found to significantly influence the rheological and cohesive properties of mud. Further research is required to investigate the effect of type of organic matter at different pH or ion type and concentrations on the rheological fingerprint of mud.
This study is funded by the Hamburg Port Authority and carried out within the framework of the MUDNET academic network: https://www.tudelft.nl/mudnet/
The authors declare no conflict of interest.
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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:{name:"Medical University Plovdiv",country:{name:"Bulgaria"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. 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Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',annualVolume:11404,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"49517",title:"Prof.",name:"Hitoshi",middleName:null,surname:"Tsunashima",fullName:"Hitoshi Tsunashima",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTP4QAO/Profile_Picture_1625819726528",institutionString:null,institution:{name:"Nihon University",institutionURL:null,country:{name:"Japan"}}},{id:"425354",title:"Dr.",name:"Marcus",middleName:"Fraga",surname:"Vieira",fullName:"Marcus Vieira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003BJSgIQAX/Profile_Picture_1627904687309",institutionString:null,institution:{name:"Universidade Federal de Goiás",institutionURL:null,country:{name:"Brazil"}}},{id:"196746",title:"Dr.",name:"Ramana",middleName:null,surname:"Vinjamuri",fullName:"Ramana Vinjamuri",profilePictureURL:"https://mts.intechopen.com/storage/users/196746/images/system/196746.jpeg",institutionString:"University of Maryland, Baltimore County",institution:{name:"University of Maryland, Baltimore County",institutionURL:null,country:{name:"United States of America"}}}]},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering",scope:"The Biotechnology - Biosensors, Biomaterials and Tissue Engineering topic within the Biomedical Engineering Series aims to rapidly publish contributions on all aspects of biotechnology, biosensors, biomaterial and tissue engineering. We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. 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