\r\n\tThe protection of biodiversity is a major target of the European Union Marine Strategy Framework Directive, requiring an assessment of the status of biodiversity on the level of species, habitats, and ecosystems including genetic diversity and the role of biodiversity in food web structure and functioning. The restoration of marine ecosystems can support the productivity and reliability of goods and services that the ocean provides to humankind, to maintain ecosystem integrity and stability. Some of the goods produced by the marine ecosystem services are fish harvests, wild plant and animal resources, water, some of the services provided recreation, tourism, breeding and nursery habitats, water transport, carbon sequestration, erosion control, and habitat provision.
",isbn:"978-1-83968-460-9",printIsbn:"978-1-83968-459-3",pdfIsbn:"978-1-83968-544-6",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"727e7eb3d4ba529ec5eb4f150e078523",bookSignature:"Dr. Ana M.M. Marta Gonçalves",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/10845.jpg",keywords:"Non-indigenous Species, Dynamics, Ecosystem Maturation, Ecological Succession, Water Quality, Recovery, Biodiversity, Environmental Status, Ecosystem Services, Goods Production, Carbohydrates, Carrageenan",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 14th 2022",dateEndSecondStepPublish:"June 22nd 2022",dateEndThirdStepPublish:"August 21st 2022",dateEndFourthStepPublish:"November 9th 2022",dateEndFifthStepPublish:"January 8th 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"2 months",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Dr. Ana Marta Gonçalves (h-index 19) holds a Ph.D. in Biology, from the University of Coimbra, Portugal, in collaboration with Ghent University, in 2011. During her research career obtained several grants is highly international competitive calls, including the MARS award for young scientists funded by The Royal Netherlands Institute for Sea Research (NIOZ) and the Foundation for Science and Technology (FCT, Portugal) grants.",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"320124",title:"Dr.",name:"Ana M.M.",middleName:"Marta",surname:"Gonçalves",slug:"ana-m.m.-goncalves",fullName:"Ana M.M. Gonçalves",profilePictureURL:"https://mts.intechopen.com/storage/users/320124/images/system/320124.jpg",biography:"Ana Marta Gonçalves obtained a Ph.D. in Biology with a specialization in Ecology from the University of Coimbra, Portugal, in collaboration with Ghent University, Belgium, in 2011. Currently, she is an auxiliary researcher at the Marine and Environmental Sciences Center (MARE), Portugal, where she is also a member of the Directive Board. Since 2016, she has been a member of the Scientific Council of the Institute for Interdisciplinary Research, University of Coimbra (IIIUC). Dr. Gonçalves holds various administrative and management positions in international networks, societies (e.g., Society of Environmental Toxicology and Chemistry, AIL), and associations (e.g., PROAQUA). She is an editorial board member and reviewer for several indexed journals. She has published more than 70 journal articles, 50 book chapters, and 165 communications in international scientific events. She participated as a member and/or coordinator in more than twenty-five national and international projects and is currently the coordinator of four research projects. She has supervised more than ninety-five national and international undergraduate and graduate students. She has experience as a teacher of university courses and in accredited training sessions for teachers. Additionally, she has coordinated several ocean literacy and environmental education activities for kindergarten and school students. During her research career, Dr. Gonçalves obtained several grants and a MARS award for young scientists funded by The Royal Netherlands Institute for Sea Research (NIOZ).\n\nShe has expertise in biosafety, biochemical pathways, and impacts of stressors in aquatic species. Her research focus is on the valorization of marine resources and their applications in the industrial sector, such as the food and pharmaceutical industries. Her studies also highlight the application of biomarker tools for monitoring and managing aquatic systems",institutionString:"University of Coimbra",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"University of Coimbra",institutionURL:null,country:{name:"Portugal"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"12",title:"Environmental Sciences",slug:"environmental-sciences"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"278926",firstName:"Ivana",lastName:"Barac",middleName:null,title:"Ms.",imageUrl:"https://mts.intechopen.com/storage/users/278926/images/8058_n.jpg",email:"ivana.b@intechopen.com",biography:"As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2270",title:"Fourier Transform",subtitle:"Materials Analysis",isOpenForSubmission:!1,hash:"5e094b066da527193e878e160b4772af",slug:"fourier-transform-materials-analysis",bookSignature:"Salih Mohammed Salih",coverURL:"https://cdn.intechopen.com/books/images_new/2270.jpg",editedByType:"Edited by",editors:[{id:"111691",title:"Dr.Ing.",name:"Salih",surname:"Salih",slug:"salih-salih",fullName:"Salih Salih"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"117",title:"Artificial Neural Networks",subtitle:"Methodological Advances and Biomedical Applications",isOpenForSubmission:!1,hash:null,slug:"artificial-neural-networks-methodological-advances-and-biomedical-applications",bookSignature:"Kenji Suzuki",coverURL:"https://cdn.intechopen.com/books/images_new/117.jpg",editedByType:"Edited by",editors:[{id:"3095",title:"Prof.",name:"Kenji",surname:"Suzuki",slug:"kenji-suzuki",fullName:"Kenji Suzuki"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3828",title:"Application of Nanotechnology in Drug Delivery",subtitle:null,isOpenForSubmission:!1,hash:"51a27e7adbfafcfedb6e9683f209cba4",slug:"application-of-nanotechnology-in-drug-delivery",bookSignature:"Ali Demir Sezer",coverURL:"https://cdn.intechopen.com/books/images_new/3828.jpg",editedByType:"Edited by",editors:[{id:"62389",title:"PhD.",name:"Ali Demir",surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"872",title:"Organic Pollutants Ten Years After the Stockholm Convention",subtitle:"Environmental and Analytical Update",isOpenForSubmission:!1,hash:"f01dc7077e1d23f3d8f5454985cafa0a",slug:"organic-pollutants-ten-years-after-the-stockholm-convention-environmental-and-analytical-update",bookSignature:"Tomasz Puzyn and Aleksandra Mostrag-Szlichtyng",coverURL:"https://cdn.intechopen.com/books/images_new/872.jpg",editedByType:"Edited by",editors:[{id:"84887",title:"Dr.",name:"Tomasz",surname:"Puzyn",slug:"tomasz-puzyn",fullName:"Tomasz Puzyn"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3569",title:"Biodegradation",subtitle:"Life of Science",isOpenForSubmission:!1,hash:"bb737eb528a53e5106c7e218d5f12ec6",slug:"biodegradation-life-of-science",bookSignature:"Rolando Chamy and Francisca Rosenkranz",coverURL:"https://cdn.intechopen.com/books/images_new/3569.jpg",editedByType:"Edited by",editors:[{id:"165784",title:"Dr.",name:"Rolando",surname:"Chamy",slug:"rolando-chamy",fullName:"Rolando Chamy"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"74374",title:"Wavelet Based Multicarrier Modulation (MCM) Systems: PAPR Analysis",doi:"10.5772/intechopen.94579",slug:"wavelet-based-multicarrier-modulation-mcm-systems-papr-analysis",body:'Orthogonal Frequency Division Multiplexing (OFDM) technique provides a number of advantages: In OFDM since the subcarriers are overlapped, accomplishes a higher degree of spectral efficiency that results in higher transmission data rates. Considering the use of the efficient FFT technique, the process is considered computationally lower. Besides, in the Single-Carrier Modulation (SCM) the ISI problem which commonly occurs the use of the cyclic prefix (CP) greatly eliminates the problem [1]. The division of a channel into several narrowband flat fading (subchannels) results in the subchannels being more resilient towards frequency selective fading. The loss of any subcarrier(s) due to channel frequency selectivity, proper channel coding schemes can recover the lost data [1]. Thus, this technique offers robust protection against channel impairments without the need to implement an equalizer as in the SCM, and this greatly reduces the overall system complexity. However, the high Peak-to-Average Power Ratio (PAPR) has been the major drawback in the OFDM system. This situation happens when the peak OFDM signals surpass the specified threshold and as a result the high-power amplifier (HPA) operates in a nonlinear region. This produces spectral regrowth of the OFDM signals and broken the orthogonality among the subcarriers. Thus, the effect on bit error rate (BER) performance at the receiver is poor.
To deliver massive high-speed data over a wireless channel, Multi-carrier-modulation (MCM) scheme has been widely used transmission technique. Despite its advantages, the MCM scheme is prone to high PAPR signal transmission, which has been single out as the main difficulty. In the MCM scheme, the conventional way to obtain orthogonal subcarrier signals is by using a Fourier transform. The emergence of wavelet transforms has paved the way for new promising techniques to obtain orthogonal subcarrier signals in future MCM systems. Wavelet transforms have been testified practical for the MCM system due to the orthogonal overlapping symbols property that they possess in time and frequency domains, respectively.
In order to mitigate PAPR, there have been many techniques proposed in literature either to reduce the peak power with fixed average power or alter the distribution so that the average power produced has smaller peak power [2, 3, 4, 5, 6]. Due to this, there are two categories of PAPR reduction techniques which are called as signal distortion technique and signal scrambling technique. A prominent technique known as Partial Transmit Sequence (PTS) has been first introduced in [7]. This technique categorized as signal scrambling offers big potential for further exploration as explored in the works [8, 9, 10, 11].
This chapter presents the analysis of various wavelet families in their applicability towards MCM systems and their PAPR profiles. Details analysis is presented for obtaining the BER results for various Wavelets.
In this section the basic concept of wavelet and wavelet packet transform (WPT) are presented. The WPT is constructed based on the continuous wavelet transform (CWT) and wavelet transform (WT) theory. For ease of reading, all the following equations in these subsections are mostly taken from [12, 13, 14, 15].
The computation cost for wavelet coefficients in the CWT is high since they are highly redundant data, which is not desirable for real application. Therefore, discrete wavelets offer as the alternative for practical applications. In discrete wavelets, the scalable and translatable wavelets are discrete. The process of discrete scaling and translation of the mother wavelet can be expressed as
where
where
In this subspace, if
One can increase the size of the subspace by changing the time scale of the scaling functions. The two-dimensional parameterization (time and scale) of scaling function
Then, the new function for the expanded subspace
In the extended subspace, whenever
From (Eq. (7)), the span
where the terms
where the term
Wavelet vector spaces and scaling function.
The definition of the wavelet function
Due to these wavelets are in space spanned by the next finer scaling function, the wavelet function
where
Both coefficients are restricted by the orthogonality condition. If
The wavelet function coefficients
and its scaling function is
Furthermore, the basic version of Haar wavelet for wavelet and scaling function is shown in Figure 2.
Haar Wavelet transform (a) mother wavelet function, (b) scaling function.
The Haar filter coefficients are obtained by applying (Eq. (9)) and (Eq. (12)).
Furthermore, the signal
where
In the wavelet expansion, by manipulating (Eq. (9)) and (Eq. (19)), the higher scale (i.e.
while the detail coefficient is expressed as
Both the terms of
DWT decomposition (single level).
The input signal to the 2-channel filter bank is split into two parts. The first portion of the signal goes to filter
DWT decomposition (three level).
On the other hand, the reconstruction of the DWT coefficients process is expressed by (Eq. (19)). If (Eq. (9)) (for scaling refinement) and (Eq. (12)) (wavelet function) are substituted into (Eq. (19)) (reconstruction function), thus produces
By multiplying both sides of (Eq. (22)) with
This implies that the scaling DWT coefficients at a certain value
DWT reconstruction (single level).
In short, the DWT decomposes signals into coefficients. The IDWT reconstructs the original signals from coefficients which can be implemented efficiently by iterating the 2-channel synthesis filter bank.
In DWT decomposition, the direction of decomposition is heading towards the low pass branches, i.e. the sequence of iteration for the 2-channel filter bank is always taking the low pass filters. At the end of decomposition, the low frequencies portion contains fewer numbers of coefficients, hence occupying a narrow bandwidth. The high frequencies portion contains larger number of coefficients, hence occupying a wide bandwidth.
On the other hand, wavelet packet transform (WPT) executes the iteration of 2-channel filter bank on both sides, i.e. on the low pass and high pass filter branches for decomposition. Therefore, the WPT has evenly space frequency resolution and similar bandwidth size since both the high frequency and low frequencies components are decomposed. In WPT, the filter bank structure is expanded into a full binary tree. A set of WPT coefficients is labeled by
In WPT, the scaling WPT coefficients are denoted as
WPT decomposition at single level.
In WPT, the number of iterations by the 2-channel filter bank increases exponentially as the number of levels increased. Therefore, WPT has higher computational complexity than the regular DWT. The WPT requires
Multicarrier modulation (MCM) scheme is a technique that transforms the high-speed serial signals into multiple low-speed parallel signals with
In this study two wavelet-based MCM systems are used i.e. the wavelet-based OFDM (WOFDM) and wavelet packet-based OFDM (WP-OFDM) systems. As seen above. The primary difference between these two MCM systems is the way the wavelet tree being expanded. Therefore, in wavelet-based OFDM (WOFDM), the decomposition process expands the branches in dyadic way. In wavelet packet-based OFDM (WP-OFDM), the decomposition process expands the nodes as a full binary tree. Hence, wavelet packet process possesses richer signal analysis than wavelets process and for the detail analysis, wavelet packet process is capable to focus on any of the tree nodes. This main difference of the two MCM systems is illustrated in Figure 7. Notice that the wavelet decomposition produces different range of bandwidth divisions. The wavelet bandwidth is in form of dyadic division, while wavelet packet bandwidth is uniform. Therefore, the use of wavelet packet transform in MCM system is preferable since its major characteristic resembles the conventional OFDM [22].
Decomposition and bandwidth division for (a) DWT and (b) WPT.
In wavelet packet-based OFDM (WP-OFDM) scheme that wavelet packet transform is utilized to change a series of parallel signals into a single composite signal. Both OFDM and WP-OFDM possess high spectral efficiency since their subcarriers are orthogonal that overlap between each other. The only difference between the two schemes is in term of the shape of the subcarriers produced. In ordinary OFDM the Fourier bases are used i.e. the sine or cosine terms. However, in WP-OFDM scheme the wavelet packet provides flexibility for modification of the filter banks property to suit the characteristic of system transmission [14]. The general multicarrier modulation system is shown in Figure 8.
General schemes for multicarrier modulation.
WP-OFDM is implemented by the using the inverse orthogonal transform at the transmitter which is known as the inverse discrete wavelet packet transform (ID-WPT) as illustrated in Figure 9 (left-hand side). The forward orthogonal transform is implemented at the receiver called as discrete wavelet packet transform (DWPT) as depicted in Figure 9 (right-hand side). The implementation of WP-OFDM that utilizes the wavelet packet transform has been derived from MRA concept [23]. It is commenced by introducing a pair of filters called as quadrature mirror filters (QMF) that contain half-band of the low and high-pass filters, i.e.
IDWPT and DWPT in MCM scheme.
The complex conjugate time reversed variant is given by [24];
The pair of
where
This section presents a comprehensive study on the PAPR profile of multicarrier modulation (MCM) signals. The performance of the transmitted signal is measured by the ratio of peak power signal to its corresponding average power signal within similar MCM frame, known as the peak-to-average power ratio (PAPR). It is desired to have a minimum PAPR as possible in order to reduce the complexity of high power amplifier (HPA) and at the same time, the average transmitting power can be boosted up efficiently as maximum as possible in a linear region of a HPA. Besides, it is disadvantageous of having high PAPR as the signals may be distorted in the nonlinear region of the HPA and results in poor reception and bit error rate (BER) performance. In order to cope with high PAPR, this chapter provides a study that investigates the wavelet-based OFDM (WOFDM), wavelet packet-based OFDM (WP-OFDM) and conventional OFDM systems performances. This investigation is carried out by replacing different orthogonal base modulations, which is normally used in Fourier based MCM (as the conventional OFDM system).
This section presents the general multicarrier modulation system model structures for implementation. The condition for determining the initial data value and maximum potential number of symbols to be carried by system subcarriers are also discussed.
The three evaluated multicarrier modulation (MCM) system models are represented by a single general MCM model as illustrated in Figure 10. The information bits are generated based on the uniform random distribution binary number. The data are arranged (in every frame) in a horizontal matrix
Model for general MCM scheme with data sequence details.
Table 1 shows four possible of
Model for wavelet- and wavelet packet-based OFDM schemes.
Model for conventional OFDM scheme.
No. of bits per symbol, | Suitable mapping type | |
---|---|---|
1 | BPSK | |
2 | QAM | |
4 | 16QAM | |
6 | 64QAM |
In Figure 11, there are two types of wavelet-based MCM models to be considered i.e. the wavelet-based OFDM (WOFDM) and wavelet packet-based OFDM (WP-OFDM) systems. At the transmitter, either the inverse discrete wavelet transform (IDWT) or inverse discrete wavelet packet transform (IDWPT) is used. At the receiver, either the discrete wavelet transform (DWT) or discrete wavelet packet transform (DWPT) is used. These modulation techniques offer higher spectral efficiency since there is no for the system to use the cyclic pre-fix (CP) codes as in the conventional OFDM.
Figure 12 shows the conventional OFDM (C-OFDM) which is included for comparison system model. This model utilizes the inverse fast Fourier transform (IFFT) and fast Fourier transform (FFT). Additional blocks are required for appending and re-moving the CP codes where 25 percent of the OFDM frames tail are copied and appended to OFDM frames head [25, 26].
Each frame must contain
This section describes how the transmission parameters values of
S/S encoding into
Figure 13 denotes three conversion processes for the initial input bit
Next,
Mapping type | Base number | Output of | Number of symbols |
---|---|---|---|
BPSK | 0,0,0,0,0,1,1,1,0,0,0,1,0,1,1,1,0,0,1,0, 1,0,0,1,1,1,1,1,0,0,1,0,0,1,1,1,1,0,1,1} | 60 | |
QAM | 0,1,1,3,0,2,1,3,3,0,2,1,3,2,3} | 30 | |
16QAM | 15 | ||
64QAM | 10 |
Output of
where
Using (Eq. (32)), the number of transmission symbols
Parameters | Value | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of subcarrier, | 64 | 128 | 256 | |||||||||
No. of bits per symbol | 1 | 2 | 4 | 6 | 1 | 2 | 4 | 6 | 1 | 2 | 4 | 6 |
No. of initial binary information, | 44 | 88 | 176 | 264 | 88 | 176 | 352 | 528 | 176 | 352 | 748 | 1100 |
No of symbols per frame | 60 | 60 | 60 | 60 | 120 | 120 | 120 | 120 | 250 | 250 | 250 | 250 |
The relationship between
Figure 14 shows the partitions between the occupied slot positions of the encoded data
MCM partition with respect to
This section presents the results and discussions on the PAPR profile performances based on several important parameters i.e. modulation types, number of subcarriers, the orthogonal bases (Fourier/Wavelets) and filter length. The BER performance is also included to investigate the efficiency of the system models. The common parameters used in the experiments are as list in Table 4 below.
Parameter | Descriptions |
---|---|
System Model | WOFDM, WP-OFDM, C-OFDM |
Encoder type | RS(15,11) |
Channel model | AWGN |
CP for conventional MCM | 25% of total subcarriers |
Common parameters for experiments.
The effect of modulation constellation mapping on PAPR is analyzed in the following paragraphs. The list of parameters involved are shown as in Table 5. Figure 15 shows that both the conventional C-OFDM and WP-OFDM systems are having almost the same PAPR profiles, regardless of the modulation mapping types used. The reason for the PAPR profiles of the wavelet based OFDM (WOFDM) outperform the PAPR profiles of the WP-OFDM, is that the WOFDM system contains a smaller number of signal analysis than the WP-OFDM system. The PAPR profile for WOFDM system is superior since the decomposition and reconstruction signals are only involved the low pass branches. Thus, there is lower probability for the peak to be above the average signals leading to slightly superior PAPR profile.
Parameter | Descriptions |
---|---|
Mapping type | QAM, 16QAM, 64QAM |
Number of subcarriers | 128 |
Orthogonal bases | Fourier, wavelet (Haar) |
Parameters used for studying the effect of different type of mapping modulation.
CCDF of the PAPR with variation of mapping type.
However, it can clearly be seen in Figure 16, the BER performances are indeed worse for all three MCM systems as the type of mapping changes from QAM towards 16QAM and 64QAM. The BER performance is highly related with the type of the signal mapping used. Theoretically, the error probability at the receiver increases as the number of constellation points increased. In order to reduce the error probability, in general higher
Corresponding BER performances due to variation of mapping type.
Mapping type | |
---|---|
QAM | 9.0 |
16QAM | 15.5 |
64QAM | 21.5 |
Common value of
The following paragraphs analyze the effect on varying the number of subcarriers on the PAPR profiles. Table 7 lists all parameters required for this experiment. It is found that, when the number of subcarriers
CCDF of the PAPR with variation of number of subcarriers.
Parameter | Descriptions |
---|---|
Mapping type | 64QAM |
Number of subcarriers | 64, 128, 256 |
Orthogonal bases | Fourier, wavelet (Haar) |
Parameters used for studying the effect of different No. of subcarriers.
Figure 18 shows that there is no significant different in term of BER performances, although different numbers of subcarriers are used for modulation. At BER of 10
Corresponding BER performance due to variation of number of subcarriers.
The following paragraphs analyze the influence of different orthogonal bases, wavelet types and their filter lengths on the PAPR profile. Several wavelet families applied includes the Daubechies, Symlet, Coiflet and Meyer wavelets with various lengths of coefficients. The parameters are briefly listed as in Table 8. This analysis is mainly focuses on the wavelet OFDM and wavelet packet-based OFDM systems. However, the C-OFDM scheme is also included as a performance reference. Additional information regarding the characteristic of the wavelet families are included in Table 9.
Parameter | Descriptions |
---|---|
Mapping type | 64QAM |
Number of subcarriers | 128 |
Orthogonal bases | Fourier, wavelet ( |
Parameters used for studying the effect of different bases and filter length.
Full name | Abbreviated name | Vanishing order | Length, |
---|---|---|---|
Haar | Haar | 1 | 2 |
Daubechies | 2 | ||
Symlets | 2 | ||
Coiflet | 6 | ||
Discrete Meyer | — | 62 |
Wavelet family characteristic [23].
Figure 19 shows the PAPR profiles for the three OFDM systems, where Daubechies wavelet with different filter lengths are used (Fourier based OFDM profile is just for reference only). In analyzing the effect of wavelet filter length, various filter lengths are used in the experiment. From Figure 19, looking at the WOFDM profiles (red color), as the filter length increases, the PAPR profiles become worse. In other words, the Daubechies wavelet (in WOFDM) with higher filter length produces inferior PAPR profiles. This is due to the fact that with higher filter length, the wavelet has richer signal analysis. Thus, there is higher probability for the peak to be above the average signals leading to slightly inferior PAPR profile.
CCDF of the PAPR with Daubechies wavelet with different filter lengths.
However, for WP-OFDM profiles (blue color), there is no significant difference in the PAPR performance. Since the signal analysis in WP-OFDM is in full binary tree analysis rather than dyadic (lower-half band) analysis in WOFDM system. There is already high amount of data involved in decomposition and reconstruction which makes the effect of wavelet filter length insignificant.
In Figures 20 and 21, different wavelet types (Daubechies, Symlet, Coiflet and Discrete Meyer wavelets) are used but the filter length is fixed
CCDF of the PAPR with different orthogonal bases modulation and
CCDF of the PAPR with different orthogonal bases modulation and
The BER performances are shown in Figure 22, where the experiment is carried out on the Daubechies wavelet with different filter lengths. It can be observed that no significant difference between BER performances. For example, at BER 10
Corresponding BER performances for Daubechies wavelet with different filter lengths.
The phenomenon of high PAPR in MCM system cannot be avoided since the signals consist of multiple low-rate parallel signals, which can be seen as the composite subcarriers in time domain representation. It is expected by using different orthogonal base for modulation, the PAPR profile can be reduced. Hence, discrete wavelet transform (DWT) and discrete wavelet packet transform (DWPT) are used for this purpose instead of fast Fourier transform (FFT). In comparison to the C-OFDM system, WOFDM and WP-OFDM systems do not need any cyclic prefix (CP) codes for their MCM frame in order to avoid intercarrier interference (ICI) and inter symbol interference (ISI).
Although, WOFDM system provides superior PAPR performance than other systems, data are lost at higher frequencies branches since signals decomposition are in dyadic (lower half-band) fashion. On the other hand, WP-OFDM system decomposes the signals in both lower and upper-band frequencies, that enrich signals analysis. The results obtained in Section 4 proves the characteristics. In addition, applying various wavelet bases do not offer much improvement in PAPR profile.
The authors would like to acknowledge the USM RU grant (Grant No. 1001/PELECT/814100), for funding this research work.
Cadmium (Cd) is an element which is extremely toxic to humans and can cause adverse effects even in small doses. Cadmium is a non-essential trace metal, which plays no recognized role in human, plant and animal development and growth. Various Environmental Protection Agency classified Cd as one of the pollutant element and include it in the list of 126 priority pollutants [1]. Lithosphere, hydrosphere and atmosphere take part in the exchange of Cd in its bio-geo-chemical cycle [2]. The aggregate industrial emission of Cd is vast and significantly contributed to bio-geo-chemical cycles, resulting Cd deposition in many ecosystems and hastening buildup of Cd both in nature and human food chain. Therefore, a variety of detrimental health effects of Cd have been identified in various parts of the world and these symptoms are increases progressively [3]. Cadmium (Cd), a hazardous heavy metal, falls into Group IIB of the periodic table and, its amounts ranging from 0.1 to 1 mg kg−1 in environment [4]. According to recent data collected in 2011, 7500, 2500 and 2000 t of Cd was emitted by China, Republic of Korea and Japan whereas globally it was 21,500 t yr.−1. After the industrial revolution, man-made activities have greatly intensified the CD level in environment. The produce and use of Cd containing batteries, dyes, electroplating, combustion of crude oil, paints (Cd use as stabilizer), phosphate fertilizer processing and waste water applications have added 3–10 folds higher Cd than natural methods to the ecology. The release of Cd into to the soil environment is responsible for some natural disasters, such as volcanic eruption, sea salt spray, wild fires, weathering of Cd containing minerals and rock, transportation and accumulation of Cd-polluted soil by water and wind [5]. Cadmium, resulting from occupational and non-occupational contact, has detrimental impact on human health through build-up of Cd in human body. Occupational contamination is primarily observed by the extraction and smelting of non-ferrous metals, the manufacturing and handling of composite-containing CDs, and e-waste recycling activities. Non-occupational Cd contamination is mainly done by smoking, feeding behavior and atmospheric Cd particles [5]. Cadmium is ingested into multiple organs within the human body
Country | Adults N 19 | Children | Adolescent 14–18 years | References |
---|---|---|---|---|
MAL/RDAa | 5.0E−02b | — | — | [11] |
RfD (oral reference dose) | 1.0E−03 | 1.0E−03 | — | [12] |
Netherland | 2.01E−02 | 4.10E−02 | 1.60E−02 | [13] |
USA | 1.08E−05 | 2.21E−05 | 8.63E−06 | [14] |
Bangladesh | 5.17E−05 | 1.06E−04 | 4.13E−05 | [15] |
Italy | 1.54E−05 to 5.48E−05 | 3.16E−05 to 1.12E−04 | 1.23E−05 4.38E−05 | [16] |
Ethiopia | 1.16E−04 | 2.37E−04 | 9.24E−05 | [17] |
Zimbabwe | 8.87E−04 | 1.81E−03 | 7.09E−04 | [18] |
China | 2.05E−04 to 2.805E−03 | 4.18E−04 to 5.72E−03 | 1.63E−04 2.23E−03 | [19] |
Sweden | 6.95E−05 | 1.42E−04 | 5.55E−05 | [14] |
Uganda | 8.22E−05 | 1.68E−04 | 6.56E−05 | [11] |
India | 8.03E−04 to 4.92E−03 | 1.64E−03 to 1.00E−02 | 6.41E−04 3.93E−03 | [13] |
Pakistan | 3.67E−05 to 8.10E−04 | 7.49E−05 to 1.66E−03 | 2.93E−05to 6.47E−04 | [17] |
France | 5.78E−03 | 1.18E−02 | 4.62E−03 | [12] |
Daily dietary intake of Cd (mg kg−1 day−1) through consumption of Cd contaminated vegetables.
MAL/RDA maximum allowable limit/recommended dietary allowance.
E−02 represents 1 × 10−2.
Cadmium (Cd) is a hazardous trace element disseminated extensively in the environment and causes implacable impact on human health even in very minute content [21]. Cadmium in lithosphere, sedimentary rocks and soil content 0.2, 0.3 and 0.53 mg kg−1 however in soil water and groundwater 5.0 and 1 μg L−1, respectively [22, 23]. Cadmium contamination in soils and groundwater arises due to both natural and anthropogenic activities and cause harmful impact as its goes into human body through drinking water and foods [24]. Cadmium is mostly geogenic by origin whereas, majority comes from natural weathering and other sources are mining, casting and smelting, irrigation with sewage water, factories and vehicular discharges, and agrochemicals are major man-made causes of Cd pollution [25, 26]. Moreover, unmonitored and unsafe garbage dumping activities have intensely raised Cd levels in soil and water bodies. At end of 1980’s it was reported that geogenic and anthropogenic sources mobilizes Cd to the biosphere 24,000 and 4.5 t yr.−1, respectively which depicted the supremacy of man-made activity [27].
Among the natural sources windblown soil particles are the main reason for atmospheric Cd contamination followed by wildfires, sea spray, volcanic emissions, and meteoric dust. In California, Burke et al. [28] estimated that forest fire enhanced the average Cd level in water bodies by 2 folds. Pacyna and Pacyna [29] and Richardson et al. [30] reported that the Global average annual emission of natural Cd is about 1400 t however, from anthropogenic sources it was 2983 t. In nature, Cd is present ubiquitously in all areas and interestingly it’s presence can be seen in remote places like ice peak of the Himalaya and North and South poles [31]. In southern Germany mainly relies on agricultural activities has Cd concentration in soil deposition was upto 0.25 g (ha*a)−1 however, in industrial western Germany the Cd deposition was quite high upto 1.4 g (ha*a)−1 [32]. Thus, indicates that anthropogenic activities have greater potential in Cd pollution.
Cadmium content in the soil is positively correlated with the weathering of parent material but, unscientific practices have worsen the input, output balance
Rock type | Average Cd content (%) | Mineral | Composition | Average Cd content (%) |
---|---|---|---|---|
Carbonate stone | 0.1 | Apatite | Ca5(F,Cl)(PO4)3 | 1.4–1.5 |
Ultramafic rocks | 0.2 | Sphalerite | (Zn,Cd)S | 2 |
Schists | 0.2 | Smithonite | ZnCO3 | < 2.35 |
Sandstone | 0.3 | Magnetite | Fe3O4 | < 3.1 |
Red shales | 0.3 | Silicates | — | 0.3–58 |
Gneisses | 0.4 | Arsenopyrite | FeAsS | < 50 |
Mafic rocks | 1.1 | Scorodite | FeAsO4. 2H2O | < 10–58 |
Granitic rocks | 1.2 | Otavite | CdCO3 | 65.2 |
Basalt | 2.2 | Greenockite | CdS | 77.8 |
Obsidian | 2.5 | Pyromorphite | Pb5Cl(PO4)3 | < 10–80 |
Organic sediment | 5.0 | Calcite | CaCO3 | < 10–230 |
Red clay | 5.6 | Marcasite | FeS2 | < 500 |
Bituminous shale | 8.0 | Chalcopyrite | CuFeS2 | < 1100 |
Limestone | 10 | Bindheimite | Pb2Sb2O6(O,OH) | 1000–10,000 |
Shale and claystone | 10 | Tetrahedrite | (Cu,Fe,Zn,Ag)12SbAs4S13 | 800–20,000 |
Bentonite | 14 | Anglesite | PbSO4 | 1200 to >10,000 |
Marlstone | 26 | Mn-oxides | MnO. nH2O | < 10,000 |
Oceanic manganese oxides | 80 | Limonite | FeO(OH). nH2O | < 10,000 |
Phosphorites | 250 | Galena | PbS | < 30,000 |
Cadmium contents in different rocks and minerals.
Geogenic sources input only 10 percent Cd in the environment however, man-made emission input 90 percent Cd in the environment. Among the various man-made sources major contribution is from manufacturing and application of P fertilizers, petroleum oil burning, smelting and casting industries, effluents from cement factories, vehicular emission, sewage sludge, landfills, municipality solid wastes, and mining activities [43, 44]. The Table 3 explained various anthropogenic activities and their impact on Cd build-up in soil and groundwater. Cadmium is mainly used in stabilization of plastics, pigments manufacturing, solar panels, nickel-cadmium batteries, and rust resistant steel production, agri-chemicals, solders, engine oil, and rubber and fabric industries [78, 79]. Brown et al. [80] reported that in 2015, globally Cd manufacture was ~24,900 metric tons and it was increases in the coming years. Among the anthropogenic sources mining and metal industries are the main reason for environmental Cd pollution followed by textiles industries, nonmetallic mineral products, fertilizers and agro-chemicals production, and leathers industries [81]. Landfills and municipal solid waste deposition are the major causes of soil pollution with Cd and in European countries municipal solid waste contain Cd level up to 3 to 12% [62]. Leachates from various sources are the main cause of Cd pollution in groundwater and Belon et al. [35] estimated that leachate form FYM, atmospheric deposition, inorganic fertilizers and municipal solid waste ranges from 10 to 25, 15–50, 30–55 and 2–5%, respectively. Another important source of Cd pollution in soil through the use of P fertilizers and P fertilizer used in various countries like Eastern Mediterranean countries, European countries and Germany the Cd content is as high as 770, 360 and 600%, respectively [37, 82]. Cadmium discharge and emitted from multiple sources gradually enters into the soil and then eventually bio-accumulates in food grains which ultimately leads to human health hazard.
Source | Type of pollution | Country/Area | Maximum Cd level | Reference |
---|---|---|---|---|
Pb mining and refinery | Atmospheric deposition | Příbram, Czech Republic | Soil: 48 mg kg−1 | [45] |
Cu mining | Waste water | Canchaque, Peru | Soil: 499 mg kg−1 | [28] |
Pb–Zn mining/refinery | Waste water | Coeur d’Alene basin, Idaho, USA | Groundwater: 77 μg L−1 | [46] |
Fe–Ni–Co mining | Waste material | Several sites in Albania | Soil: 14 mg kg−1 | [47] |
Au–Ag–Pb–Zn mining | Waste water | Chloride, Arizona USA | Groundwater: 19 μg L−1 | [48] |
As refinery | Waste material | Reppel, Belgium | Soil: 79 mg kg−1 | [49] |
Phosphorite mining | Mining waste, transport | Kpogamé, Hahotoé, Togo | Soil: 43 mg kg−1 | [50] |
Zn smelter | Atmospheric deposition | Hezhang County, China | Soil: 74 mg kg−1 | [51] |
Zn smelter | Waste material | Celje, Slovenia | Soil: 344 mg kg−1 | [52] |
Pb–Zn mining/refinery | Atmospheric deposition and waste water | Jinding, China | Soil: 531 mg kg−1 | [53] |
Mining activities | Waste water | BacKan province, North Vietnam | Soil: 4.26 mg kg−1 Irrigation water: 2.51 μg L−1 | [54] |
Au–Cu mining | Waste water | Bolnisi, Georgia | Soil: 121.5 mg kg−1 | [55] |
Coal mining | Mining waste and deposition | Anhui province, eastern China | Soil: 0.05–0.87 mg kg−1 | [56] |
Cu, Mo and Ni mining | Mining waste and deposition | Yangjiazhangzh and Dexing, China | Soil: 22.8 mg kg−1 Sediment: 66.1 mg kg−1 | [57] |
Coal mines | Atmospheric deposition and waste water | Singrauli, India | Groundwater: 108 ppb | [58] |
Cement factory | Atmospheric deposition | Qadissiya, Jordan | Soil: 13 mg kg−1 | [59] |
Various ( | Waste water | Coimbatore, India | Soil: 12.8 mg kg−1 | [42] |
Ceramic industry | Sewage sludge | Castellon, Spain | Soil: 72 mg kg−1 | [60] |
Pigment manufacture | Atmospheric deposition | Staffordshire, UK | Soil: 16 mg kg−1 | [61] |
Textile industry | Waste water | Haridwar, India | Soil: 83.6 mg kg−1 Groundwater: 40 μg L−1 | [62] |
Metal industry | Atmospheric deposition | Unnao, India | Groundwater: 74 μg L−1 | [63] |
Ceramic industry | Atmospheric deposition | Yixing, China | Soil: 5.9 mg kg−1 | [64] |
Paper mill | Waste water | Morigaon, India | Soil: 31.01 mg kg−1 | [65] |
Power industry and industrial plants | Atmospheric deposition and waste water | Malopolska province, southern Poland | Soil: 16.9 mg kg−1 | [66] |
Zinc-smelter plant | Irrigation through industrial effluents | Rajasthan, India | Soil: 96.8 mg kg−1 | [67] |
Atlas Cycle factory | Irrigation through industrial effluents | Haryana, India | Soil: 9.81 mg kg−1 | [67] |
Disposal facilities | Leachate | Great lakes region, USA | Soil: 32 mg kg−1 | [40] |
Household wastes | Waste water | Ikare, Nigeria | Groundwater: 580 μg L−1 | [6] |
Landfill | Leachate | Taoyuan, Taiwan Alexandria, Egypt | Soil: 378 mg kg−1 Groundwater: 51 μg L−1 | [68] |
Sewage and waste disposal | Waste water | Sekondi-Takoradi Metropolis, Ghana | Groundwater: 90 μg L−1 | [69] |
Sewage disposal | Waste water and physical mixing | Sundarban, India | Soil: 1.70 mg kg−1 | [70] |
Brownfield | Waste water | Xiangjiang River, China | Groundwater: 474 μg L−1 | [71] |
Oil spill accident | Waste deposition and physical mixing | Sundarban, Bangladesh | Sediment: 0.82 mg kg−1 | [38] |
Electronical waste recycling | Waste water | Krishna Vihar, India | Soil: 47.7 mg kg−1 Groundwater: 280 μg L−1 | [72] |
Sewage sludge application | Irrigation | Several sites in Spain | Soil: 90 mg kg−1 | [73] |
P fertilizer production | Atmospheric deposition | Rio Grande, Brazil | Soil: 9.3 mg kg−1 Groundwater: 3 μg L−1 | [32] |
P fertilizer application | Infiltration | Cauvery River basin, India | Groundwater: 60 μg L−1 | [74] |
Urban agriculture | Atmospheric pollution and soil contamination | Belo Horizonte, Brazil | Soil: 0.20 mg kg−1 | [75] |
Sewage sludge application | Soil application | Jiangsu Province, China | Leachate: 0.14 mg kg−1 | [76] |
Sewerage | Leakage | Rastatt, Germany | Groundwater: 5 μg L−1 | [1] |
Road traffic | Infiltration | Celle, Germany | Groundwater: 2.34 μg L−1 | [9] |
Over populated, E-wastes and industrialized | Infiltration and physical mixing | Western Uttar Pradesh, India | Groundwater: 0.07 mg L−1 | [77] |
Various types of cadmium contamination in soil and waterbodies.
Cadmium (Cd) is a potent pestilential metal which enters primarily via plant roots, get distributed and accumulated in plant parts in different proportions and concentrations, hampering crop yield and deteriorating the quality of produce. It ultimately makes it way to enter food chain thereby possessing serious threat to human and animal health. Cadmium ranks 7 among the top 20 toxins and it enter to arable land through various industrial processes and farming practices [83].
Accumulation of Cd in plant is facilitated by its mobilization, uptake and transport/distribution in various plant parts. Unscientific agricultural practices and industrial effluents are the major contributor of Cd in soil [84]. Phosphaic fertilizer and sewage-sludge contribute to Cd pollution in agricultural soil. Concentration of Cd in plants is also an indicative of its concentration in soil; however various other factors including soil pH, organic matter content, interaction with other ions and plant species govern its availability in plants [85, 86, 87]. Meta data analysis of 162 wheat and 215 barley grain samples by Adams and associates, [88] showed grain Cd concentration is positively correlated with soil total cd content and soil reaction (pH). They also highlighted the fact that higher microbial activity, nitrification and application of sewage sludge increased the chance of Cd toxicity but, reclaiming the soil with liming may abate the chance of toxicity. Sauvé et al. [89] found that organic matter had almost 30 times more sorption affinity for Cd when compared with mineral soil in Canada which indicates the importance of quality of organic matter in binding and accumulating Cd. It is assumed that lowering of pH will facilitate Cd availability to plants, but it might not hold true for soils with lower pH and high organic matter.
Before apprehending the mechanism of Cd accumulation in plants, one has to understand uptake and translocation of Cd inside plants. Ability of plants to take up Cd depends upon numerous factors like total Cd content in soil solution, soil reaction (pH), redox potential (Eh) and moisture content, soil organic carbon content, soil temperature, and last but not the least interaction among different elements. Primarily Cd enters plant through roots. Once in roots, Cd can get stored or exported to shoots through xylem. Cadmium is both xylem and phloem mobile [54, 74]. There are two possible mechanisms of Cd translocation into the plants and subsequently to the grains. These are: (i) Xylem mediated translocation to the sink i.e. grains (ii) Active transportation to various plant parts culm, rachis, flag leaves, external parts of the panicles and followed by phloem mediated mobilization to grains [90] and Schematic representation of Cd uptake and subsequent translocation in rice was shown in Figure 1. Root cell membrane located transporters take key role in Cd uptake in plants [91].
Schematic model of Cd uptake process from soil to grains in rice.
Cadmium uptake and accumulation in plants must undoubtedly be under control of multiple genes which contribute quantitatively in stage-specific, tissue-specific, environment-specific to Cd transport, accumulation and sequestration in plants [92]. In a study conducted by Hédiji et al. [72] on long term exposure of Cd on tomato (
The impact of Cd toxicity in plants is still a closed book thing but, recent advances in plant physiological studies helped the researchers to answer the questions. Clemens [54] reported that the major influence on Cd toxicity in plants is nutrient imbalance by regulating the normal work of transporters peculiarly in fruit plants. For instance, the concentration of K, Zn, and Fe in developing fruits falls off drastically at the expense of Ca and Mg. The antagonistic relationship between Cd and K is well documented like sub-optimal K concentration in the pericarp which disrupts the normal bio-chemical cycles like bio-synthesis of protein, enzymatic activity and membrane bound activities such as sustaining cellular turgidity [54].
According to International Agency for Research on Cancer, Cd is highly inimical and labeled as class-I carcinogenic compound to mammalian health. Cadmium may not be toxic to the plants that accumulate it, yet are toxic to animals and humans feeding upon it. Cadmium makes it entry to human body either from food, water or breath and a little amount enters through skin. Majority of Cd entering to human body is either breathed out or excreted in feces, whereas only one-quarter of it gets into human body through breath and one-twentieth from food. People working in industries that release Cd are more prone to get affected by Cd toxicity because they might breath, eat or drink Cd in air, food or water. Cadmium with biological half-life of 10–30 years, generally gets accumulated in kidneys and liver and slowly leaves human body through urine or feces [93, 94]. Researches around the world indicate that daily cadmium intake from all sources is very low in case of general population which range between 10 and 25 μgday−1, however the tolerable daily intake established by WHO is 60 and 70 10–25 μg day−1 respectively, for adult women and men.
Human health due to Cd is an emerging issue and needs urgent attentions [52]. During the process, 10–50% of the cadmium dust is consumed according to the particle size. Digestion is higher for people that have an iron, calcium or zinc deficiency. The main source of human cadmium toxicity is considered to be tobacco smoking other than industrial exposures and food habit [95, 96, 97, 98]. Cd toxicity is developing gradually in the human body and eventually causes different negative health effects, particularly bone loss and nephron toxicity.
Cd is passed across the body after assimilation, usually linked with a bunch of sulfhydryl containing protein such as metalllothionine. Typically 30% stores in liver and kidney; the remaining spread across the body, with an independence half-life about a quarter of a century [99]. Blood, hair and urine Cd levels are indicator of potential toxicity but, to get the actual toxicity level urine stimulation test with the subjects body weight is highly important [100].
As previously mentioned, Cd induced epigenetic changes in DNA articulation by oxidative pressure, impediments or guidance for transport pathways particularly in the kidney [98] (Figure 2). Extreme impedance to the physiological function of Zn or Mg is introduced by other pathological mechanisms [99]. Restriction of the heme and the weakening of mitochondrial work which is likely to cause apoptosis [47]. Glutathione explosion has been found alongside the auxiliary protein contortion attributable to the official Cd in sulfhydryl bunches [100]. Cooperation with other hazardous metals, such as lead (Pb) and arsenis (As) hastens these impacts [101, 102].
Mechanisms of cadmium toxicity in humans.
The major site of Cd toxicity is kidney where a fragment S1 of the proximal tubule is a majorly targeted and disruption in mitochondrial protein synthesis due reabsorption of glucose, bicarbonate and phosphate clinically known as Fanconi disorder [76, 103]. Cadmium can also inhibit the digestion of vitamin D in the kidneys with progressively rises of issues like osteomalacia, osteoporosis, renal-around broking and calcium malabsorption [103, 104, 105]. Cadmium has multiple deleterious effects on the cardiovascular framework like adverse impact on vascular endothelium consistency [95, 106]. Cd links to sudden coronary death marginal blood vessel dysfunction, increased intima media thickness and scattered myocardial necrosis [64, 107]. In comparison, low-recurrence listening was substantially decreased by people with elevated urinary Cd levels [108]. In comparison, high-urinary Cd rates have decreased cognitive power. Cadmium is assumed to be the carcinogenic agent Class B1 by the United States Environmental Protection Agency [46]. Conflicting research links Cd adoption and denies bosom malignant development [88, 94, 109]. Cd was associated to pancreas and lymphoma cell disturbance [88]. Vegetables developed in Cd-defiled soils can possibly cause toxicological issues in people particularly in developing women [110]. A few different components like low admission of Ca, vitamin D, and minor components, for example, Cu and Zn can build this sum. Thus, daily entry of Cd by Cd is exceptional due to the fusion of Cd in diets and the human dietary propensities. The mean daily use of Cd (DICd) uses the following formula as a general basis:
DICd symbolizes daily intake of Cd, CCdCofactor, intake of Dfood and Waverage weight are Cd fixations in vegetables, transition factor (new weight to dry weight), and human consumption of vegetables every day and regular body weight respectively. Table 2 describes the DICd figures given in different countries by the use of Cd-sullied vegetables. The number of inhabitants in the Netherlands unmistakably ingests the most notable Cd from the available information through defiled vegetables, followed by France and USA. The introduced data shows that the use of Cd contaminated nourishments is a significant implementation course. In these lines, in order to avoid harmful health consequences, the intake of infected vegetables should be reduced to the fullest degree possible. Different remediation steps can also be introduced in infected soil to carry the Cd concentration to a reasonable amount. In contrast, DICd’s principles are based on a few experiments worldwide. To describe incidents and potential dangers more thoroughly, further studies are needed. Furthermore, day-to-day vegetable intake, eating patterns, general status and the overall body weight of a person should be taken into account. Cadmium (Cd) is a toxicity ia result of long term exposure and “
According to EPA, bioremediation can be defined as “technique which uses naturally occurring microorganisms to break down hazardous substances into less toxic or non-toxic substances [111].”
Microbe’s works in both active and passive mode and microbial species like bacteria, fungi and alage can be used as a potential option for eco-friendly remediation techniques [93]. Bacteria’s are very effective for cleaning contaminated site due to its unique metabolic characters and tolerance to harsh conditions [120]. Several heavy metals have been tested using bacteria species like
This present chapter summarizes the various sources of Cd in environment and its toxic effects on plant and human being as well as suggested some approaches of bioremediation to mitigate the Cd pollution from environment. Anthropogenic activities are the key pathway to contaminate the environment with Cd which ultimately accumulated in various leafy vegetables and food grains. Consumption of this high Cd containing food causes several toxic symptoms in human being and leads to malfunctioning of multiple human organs. To reduce the Cd accumulation in food grain various amelioration strategies has been adopted among them use of microbes to decrease Cd uptake by plants seems to have great prospective. Moreover, some microbes may increase amounts of Cd due to their biochemical processes, and their implementation may also worsen problems with soil pollution. Use It is also suggested to characterize the microbes and tested them in laboratory and field condition prior to their use in agricultural soils, thus maintaining soil quality and food safety.
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His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. 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This has compromised the ability of the environment to foster life and render its intrinsic values. Heavy metals are known to be naturally occurring compounds, but anthropogenic activities introduce them in large quantities in different environmental compartments. This leads to the environment’s ability to foster life being reduced as human, animal, and plant health become threatened. This occurs due to bioaccumulation in the food chains as a result of the nondegradable state of the heavy metals. Remediation of heavy metals requires special attention to protect soil quality, air quality, water quality, human health, animal health, and all spheres as a collection. Developed physical and chemical heavy metal remediation technologies are demanding costs which are not feasible, time-consuming, and release additional waste to the environment. This chapter summarises the problems related to heavy metal pollution and various remediation technologies. 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Muedi",authors:[{id:"225304",title:"Dr.",name:"Vhahangwele",middleName:null,surname:"Masindi",slug:"vhahangwele-masindi",fullName:"Vhahangwele Masindi"},{id:"241403",title:"M.Sc.",name:"Khathutshelo",middleName:"Lilith",surname:"Muedi",slug:"khathutshelo-muedi",fullName:"Khathutshelo Muedi"}]},{id:"37067",doi:"10.5772/35482",title:"Fourier Transform Infrared Spectroscopy for Natural Fibres",slug:"fourier-transform-infrared-spectroscopy-for-natural-fibres",totalDownloads:9291,totalCrossrefCites:167,totalDimensionsCites:400,abstract:null,book:{id:"2270",slug:"fourier-transform-materials-analysis",title:"Fourier Transform",fullTitle:"Fourier Transform - Materials Analysis"},signatures:"Mizi Fan, Dasong Dai and Biao Huang",authors:[{id:"104647",title:"Prof.",name:"Mizi",middleName:null,surname:"Fan",slug:"mizi-fan",fullName:"Mizi Fan"}]},{id:"42566",doi:"10.5772/53706",title:"Challenges and Opportunities for Spark Plasma Sintering: A Key Technology for a New Generation of Materials",slug:"challenges-and-opportunities-for-spark-plasma-sintering-a-key-technology-for-a-new-generation-of-mat",totalDownloads:9168,totalCrossrefCites:99,totalDimensionsCites:213,abstract:null,book:{id:"3478",slug:"sintering-applications",title:"Sintering Applications",fullTitle:"Sintering Applications"},signatures:"M. Suárez, A. Fernández, J.L. Menéndez, R. Torrecillas, H. U. Kessel, J. Hennicke, R. Kirchner and T. Kessel",authors:[{id:"102383",title:"Dr.",name:"Marta",middleName:null,surname:"Suárez",slug:"marta-suarez",fullName:"Marta Suárez"},{id:"103822",title:"Dr.",name:"J.L",middleName:null,surname:"Menendez",slug:"j.l-menendez",fullName:"J.L Menendez"},{id:"103833",title:"Prof.",name:"Ramón",middleName:null,surname:"Torrecillas",slug:"ramon-torrecillas",fullName:"Ramón Torrecillas"},{id:"162633",title:"Dr.",name:"Adolfo",middleName:null,surname:"Fernández",slug:"adolfo-fernandez",fullName:"Adolfo Fernández"}]},{id:"23617",doi:"10.5772/24118",title:"Collagen- vs. Gelatine-Based Biomaterials and Their Biocompatibility: Review and Perspectives",slug:"collagen-vs-gelatine-based-biomaterials-and-their-biocompatibility-review-and-perspectives",totalDownloads:9461,totalCrossrefCites:63,totalDimensionsCites:203,abstract:null,book:{id:"1487",slug:"biomaterials-applications-for-nanomedicine",title:"Biomaterials",fullTitle:"Biomaterials Applications for Nanomedicine"},signatures:"Selestina Gorgieva and Vanja Kokol",authors:[{id:"55577",title:"Prof.",name:"Vanja",middleName:null,surname:"Kokol",slug:"vanja-kokol",fullName:"Vanja Kokol"},{id:"61285",title:"BSc",name:"Selestina",middleName:null,surname:"Gorgieva",slug:"selestina-gorgieva",fullName:"Selestina Gorgieva"}]},{id:"46243",doi:"10.5772/57255",title:"Corrosion Inhibitors – Principles, Mechanisms and Applications",slug:"corrosion-inhibitors-principles-mechanisms-and-applications",totalDownloads:13737,totalCrossrefCites:40,totalDimensionsCites:163,abstract:null,book:{id:"3817",slug:"developments-in-corrosion-protection",title:"Developments in Corrosion Protection",fullTitle:"Developments in Corrosion Protection"},signatures:"Camila G. Dariva and Alexandre F. Galio",authors:[{id:"169261",title:"Dr.",name:"Camila",middleName:"G.",surname:"Dariva",slug:"camila-dariva",fullName:"Camila Dariva"},{id:"170138",title:"Dr.",name:"Alexandre",middleName:"Ferreira",surname:"Galio",slug:"alexandre-galio",fullName:"Alexandre Galio"}]}],mostDownloadedChaptersLast30Days:[{id:"76780",title:"Basics of Clay Minerals and Their Characteristic Properties",slug:"basics-of-clay-minerals-and-their-characteristic-properties",totalDownloads:1930,totalCrossrefCites:16,totalDimensionsCites:25,abstract:"Clay minerals such as kaolinite, smectite, chlorite, micas are main components of raw materials of clay and formed in presence of water. A large number of clays used to form the different structure which completely depends on their mining source. They are known as hydrous phyllosilicate having silica, alumina and water with variable amount of inorganic ions like Mg2+, Na+, Ca2+ which are found either in interlayer space or on the planetary surface. Clay minerals are described by presence of two-dimensional sheets, tetrahedral (SiO4) and octahedral (Al2O3). There are different clay minerals which are categorized based on presence of tetrahedral and octahedral layer in their structure like kaolinite (1:1 of tetrahedral and octahedral layers), smectite group of clay minerals (2:1 of tetrahedral and octahedral layers) and chlorite (2:1:1 of tetrahedral, octahedral and octahedral layers). The particle size of clay minerals is <2microns which can be present in form of plastic in presence of water and solidified when dried. The small size and their distinctive crystal structure make clay minerals very special with their unique properties including high cation exchange capacity, swelling behavior, specific surface area, adsorption capacity, etc. which are described in this chapter. Due to all these unique properties, clay minerals are gaining interest in different fields.",book:{id:"10949",slug:"clay-and-clay-minerals",title:"Clay and Clay Minerals",fullTitle:"Clay and Clay Minerals"},signatures:"Neeraj Kumari and Chandra Mohan",authors:[{id:"258132",title:"Dr.",name:"Chandra",middleName:null,surname:"Mohan",slug:"chandra-mohan",fullName:"Chandra Mohan"},{id:"352399",title:"Dr.",name:"Neeraj",middleName:null,surname:"Kumari",slug:"neeraj-kumari",fullName:"Neeraj Kumari"}]},{id:"51535",title:"An Introduction to Hydrogels and Some Recent Applications",slug:"an-introduction-to-hydrogels-and-some-recent-applications",totalDownloads:11734,totalCrossrefCites:70,totalDimensionsCites:140,abstract:"Hydrogels have existed for more than half a century, and today they have many applications in various processes ranging from industrial to biological. There are numerous original papers, reviews, and monographs focused on the synthesis, properties, and applications of hydrogels. This chapter covers the fundamental aspects and several applications of hydrogels based on the old and the most recent publications in this field.",book:{id:"5251",slug:"emerging-concepts-in-analysis-and-applications-of-hydrogels",title:"Emerging Concepts in Analysis and Applications of Hydrogels",fullTitle:"Emerging Concepts in Analysis and Applications of Hydrogels"},signatures:"Morteza Bahram, Naimeh Mohseni and Mehdi Moghtader",authors:[{id:"179718",title:"Prof.",name:"Morteza",middleName:null,surname:"Bahram",slug:"morteza-bahram",fullName:"Morteza Bahram"},{id:"185713",title:"Dr.",name:"Naimeh",middleName:null,surname:"Mohseni",slug:"naimeh-mohseni",fullName:"Naimeh Mohseni"},{id:"185714",title:"Dr.",name:"Mehdi",middleName:null,surname:"Moghtader",slug:"mehdi-moghtader",fullName:"Mehdi Moghtader"}]},{id:"70661",title:"Bioremediation Techniques for Polluted Environment: Concept, Advantages, Limitations, and Prospects",slug:"bioremediation-techniques-for-polluted-environment-concept-advantages-limitations-and-prospects",totalDownloads:2672,totalCrossrefCites:10,totalDimensionsCites:27,abstract:"Environmental pollution has been rising in the past few decades due to increased anthropogenic activities. Bioremediation is an attractive and successful cleaning technique to remove toxic waste from polluted environment. Bioremediation is highly involved in degradation, eradication, immobilization, or detoxification diverse chemical wastes and physical hazardous materials from the surrounding through the all-inclusive and action of microorganisms. The main principle is degrading and converting pollutants to less toxic forms. Bioremediation can be carried out ex-situ and in-situ, depending on several factors, which include but not limited to cost, site characteristics, type, and concentration of pollutants. Hence, appropriate bioremediation technique is selected. Additionally, the major methodologies to develop bioremediation are biostimulation, bioaugmentation, bioventing, biopiles, and bioattenuation provided the environmental factors that decide the completion of bioremediation. Bioremediation is the most effective, economical, eco-friendly management tool to manage the polluted environment. All bioremediation techniques have its own advantage and disadvantage because it has its own specific applications.",book:{id:"9343",slug:"trace-metals-in-the-environment-new-approaches-and-recent-advances",title:"Trace Metals in the Environment",fullTitle:"Trace Metals in the Environment - New Approaches and Recent Advances"},signatures:"Indu Sharma",authors:[{id:"301262",title:"Associate Prof.",name:"Indu",middleName:null,surname:"Sharma",slug:"indu-sharma",fullName:"Indu Sharma"}]},{id:"18275",title:"Modeling and Identification of Parameters the Piezoelectric Transducers in Ultrasonic Systems",slug:"modeling-and-identification-of-parameters-the-piezoelectric-transducers-in-ultrasonic-systems",totalDownloads:10197,totalCrossrefCites:3,totalDimensionsCites:5,abstract:null,book:{id:"201",slug:"advances-in-ceramics-electric-and-magnetic-ceramics-bioceramics-ceramics-and-environment",title:"Advances in Ceramics",fullTitle:"Advances in Ceramics - Electric and Magnetic Ceramics, Bioceramics, Ceramics and Environment"},signatures:"Pawel Fabijanski and Ryszard Lagoda",authors:[{id:"13086",title:"Dr.",name:"Pawel",middleName:null,surname:"Fabijański",slug:"pawel-fabijanski",fullName:"Pawel Fabijański"}]},{id:"60680",title:"Environmental Contamination by Heavy Metals",slug:"environmental-contamination-by-heavy-metals",totalDownloads:16251,totalCrossrefCites:187,totalDimensionsCites:407,abstract:"The environment and its compartments have been severely polluted by heavy metals. This has compromised the ability of the environment to foster life and render its intrinsic values. Heavy metals are known to be naturally occurring compounds, but anthropogenic activities introduce them in large quantities in different environmental compartments. This leads to the environment’s ability to foster life being reduced as human, animal, and plant health become threatened. This occurs due to bioaccumulation in the food chains as a result of the nondegradable state of the heavy metals. Remediation of heavy metals requires special attention to protect soil quality, air quality, water quality, human health, animal health, and all spheres as a collection. Developed physical and chemical heavy metal remediation technologies are demanding costs which are not feasible, time-consuming, and release additional waste to the environment. This chapter summarises the problems related to heavy metal pollution and various remediation technologies. A case study in South Africa mines were also used.",book:{id:"6534",slug:"heavy-metals",title:"Heavy Metals",fullTitle:"Heavy Metals"},signatures:"Vhahangwele Masindi and Khathutshelo L. Muedi",authors:[{id:"225304",title:"Dr.",name:"Vhahangwele",middleName:null,surname:"Masindi",slug:"vhahangwele-masindi",fullName:"Vhahangwele Masindi"},{id:"241403",title:"M.Sc.",name:"Khathutshelo",middleName:"Lilith",surname:"Muedi",slug:"khathutshelo-muedi",fullName:"Khathutshelo Muedi"}]}],onlineFirstChaptersFilter:{topicId:"14",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"83080",title:"Boron Doping in Next-Generation Materials for Semiconductor Device",slug:"boron-doping-in-next-generation-materials-for-semiconductor-device",totalDownloads:2,totalDimensionsCites:0,doi:"10.5772/intechopen.106450",abstract:"The article surveys the most recent achievements starting with the boron doping mechanism, mainly focused on doping in semiconductor materials such as Si, Ge, graphene, carbon nanotube, or other 2D materials. Frequently used doping methodologies are discussed, including ion implantation and solid-phase doping, mainly focused on recent developing techniques of monolayer doping. These doped materials’ structural, electronic, and chemical properties are addressed to understand the boron doping effect better. Theoretical and experimental information and data are used to support such atomic-level effects. Therefore, this review can provide valuable suggestions and guidelines for materials’ properties manipulation by boron doping for further research exploration.",book:{id:"11762",title:"Characteristics and Applications of Boron",coverURL:"https://cdn.intechopen.com/books/images_new/11762.jpg"},signatures:"Linh Chi T. Cao, Luqman Hakim and Shu-Han Hsu"},{id:"83055",title:"Boron Clusters in Biomedical Applications: A Theoretical Viewpoint",slug:"boron-clusters-in-biomedical-applications-a-theoretical-viewpoint",totalDownloads:6,totalDimensionsCites:0,doi:"10.5772/intechopen.106215",abstract:"In this chapter, we presented an analysis of the recent advances in the applications of boron clusters in biomedical fields such as the development of biosensors and drug delivery systems on the basis of quantum chemical calculations. Biosensors play an essential role in many sectors, e.g., law enforcement agencies for sensing illicit drugs, medical communities for detecting overdosed medications from human and animal bodies, etc. The drug delivery systems have theoretically been proposed for many years and subsequently implemented by experiments to deliver the drug to the targeted sites by reducing the harmful side effects significantly. Boron clusters form a rich and colorful family of atomic clusters due to their unconventional structures and bonding phenomena. Boron clusters and their complexes have various biological activities such as the drug delivery, imaging for diagnosis, treatment of cancer, and probe of protein-biomolecular interactions. For all of these reactivities, the interaction mechanisms and the corresponding energetics between biomaterials and boron clusters are of essential importance as a basic step in the understanding, and thereby design of relevant materials. During the past few years, attempts have been made to probe the nature of these interactions using quantum chemical calculations mainly with density functional theory (DFT) methods. This chapter provides a summary of the theoretical viewpoint on this issue.",book:{id:"11762",title:"Characteristics and Applications of Boron",coverURL:"https://cdn.intechopen.com/books/images_new/11762.jpg"},signatures:"Ehsan Shakerzadeh, Elham Tahmasebi, Long Van Duong and Minh Tho Nguyen"},{id:"83048",title:"Structural, Magnetic, and Magnetodielectric Properties of Bi-Based Modified Ceramic Composites",slug:"structural-magnetic-and-magnetodielectric-properties-of-bi-based-modified-ceramic-composites",totalDownloads:2,totalDimensionsCites:0,doi:"10.5772/intechopen.106569",abstract:"In this chapter, we introduce a promising composite material, which can be used as a potential candidate in the field of charge storage, sensors, and spintronic devices. The structural, magnetic, and magnetodielectric properties of the pure cum composite samples are investigated. The Rietveld refinement of the X-ray data confirmed the presence of a single (A21am) and mixed phases (A21am + R-3c + Pbam) in the pure and composite sample, correspondingly. The SEM microstructure suggests the contrasting nature of the homogeneous and heterogeneous distribution of grains in the corresponding pure and composite sample. The magnetic properties of the composite sample increase due to the enhanced exchange interaction between the different magnetic ions. The frequency-dependent dielectric subjected to a constant magnetic field indicates the signature of magnetodielectric (MD) coupling for both the samples. The field variation of the MD loop shows the symmetric hysteresis loop in the composite due to the addition of magnetostrictive La0.67Sr0.33MnO3 and the non-collinear antiferromagnetic Bi2Fe4O9 phase. The maximum value of MD% (~0.12%) is enhanced by ~13 times in the composite than in the pure sample. Therefore, the improved MD coupling and symmetric switching of the MD loop of the composite make it a suitable candidate for low power consumption storage devices.",book:{id:"11117",title:"Smart and Advanced Ceramics and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11117.jpg"},signatures:"Rasmita Jena, Kouru Chandrakanta and Anil Kumar Singh"},{id:"83035",title:"Breaking the Property Trade-Offs by Using Entropic Conceptions",slug:"breaking-the-property-trade-offs-by-using-entropic-conceptions",totalDownloads:11,totalDimensionsCites:0,doi:"10.5772/intechopen.106532",abstract:"Entropic conception has been used as an effective strategy for developing materials to break the property recordings of current materials, for example, breaking the trade-off between the high-strength and low-ductility structural alloys. The performance of materials usually under a complex circumstance, a balance of multiple properties, for example, combined the high-strength, high ductility, high conductivity, high corrosion resistance, high irradiation resistance, etc., the strategy of high-entropy-alloy (HEA) will provide a materials design and development technology to realize the goal. Magnetic materials usually exhibit excellent magnetic properties but weak mechanical properties and corrosion resistance. The reported unique behaviors of HEAs, for example, self-healing effects may be the mechanism for the high irradiation resistance of the HEAs, and self-sharpening behaviors of the tungsten-based HEAs main closely be related to the serration behaviors.",book:{id:"11468",title:"High Entropy Materials - Microstructures and Properties",coverURL:"https://cdn.intechopen.com/books/images_new/11468.jpg"},signatures:"Yong Zhang and Xuehui Yan"},{id:"82929",title:"Prediction of Solubility and Miscibility Parameters of Bismuth-Arsenic Complex and Amorphous Mineral Compounds Using Molecular Dynamics Simulation",slug:"prediction-of-solubility-and-miscibility-parameters-of-bismuth-arsenic-complex-and-amorphous-mineral",totalDownloads:4,totalDimensionsCites:0,doi:"10.5772/intechopen.106316",abstract:"Bismuth is one of the most difficult impurities to remove in mining concentrates and low concentrations generate problems in silver and copper refineries. Therefore, financial penalties are established when concentrations exceed 0.05%. Some researchers had used arsenic to remove bismuth with results of up to 52% of extraction. Unfortunately, this mechanism is not yet fully understood. The objective of this research was to obtain the solubility parameters of amorphous mineral compounds, including bismuth-based compounds, through computational simulation using molecular dynamics. The composition of the mineral sample was determined by X-ray diffraction and the crystalline species were obtained and modeled using Materials Studio software. The nanostructures were optimized by an energy minimization methodology using the Broyden-Fletcher-Goldfarb-Shanno algorithm and were validated using the figure of merit equation and density. Simulations were performed using the Universal Force Field at constant pressure and temperature. The results of the minerals identified in the sample were compared with arsenic trioxide, indicating miscibility between As2O3 and Bi2O3, possible miscibility with 10 other minerals, and immiscibility with the rest. The results indicate that As2O3 can be successfully used for the removal of Bi2O3 without a negative effect on the recovery of other minerals of higher commercial value.",book:{id:"11467",title:"Bismuth-Based Nanostructured Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11467.jpg"},signatures:"Francisco Adrián De la Torre-Martínez, Efren Delgado, María Dolores Josefina Rodríguez Rosales, Hiram Medrano-Roldán, Javier López-Miranda and Damián Reyes-Jáquez"},{id:"82940",title:"Role of Surface Defects and Optical Band-gap Energy on Photocatalytic Activities of Titanate-based Perovskite Nanomaterial",slug:"role-of-surface-defects-and-optical-band-gap-energy-on-photocatalytic-activities-of-titanate-based-p",totalDownloads:4,totalDimensionsCites:0,doi:"10.5772/intechopen.106253",abstract:"In recent years, water pollution has become one of the major challenges faced by humans because of consistent rise in population and industrial activities. Water pollution due to discharge from cosmetics and pharmaceutical wastes, organic dyes, and heavy metal seen as carcinogens has the potential to disrupt hormonal processes in the body. Different approaches such as chlorination, aerobic treatment, aeration, and filtration have been deployed to treat wastewaters before being discharged into the streams, lakes, and rivers. However, more attention has been accorded to treatment approaches that involve use of nanomaterial due to non-secondary pollution, energy efficiency, and ease of operation. Titanate-based perovskite (TBP) is one of the most frequently studied nanomaterials for photocatalytic applications because of its stability and flexibility in optical band-gap modification. This chapter provided an overview of basic principles and mechanisms of a semiconductor photocatalyst, and current synthesis techniques that have been used in formulating TBP nanomaterial. The effect of reaction conditions and approaches such as doping, codoping, composites, temperature, pH, precursor type, surface area, and morphology on surface defects and optical band-gap energy of TBP nanomaterial was highlighted. Importantly, the impact of surface defects and optical band-gap energy of TBP on its photocatalytic activities was discussed. Finally, how to enhance the degradation efficiency of TBP was proposed.",book:{id:"11469",title:"Recent Advances in Perovskite Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11469.jpg"},signatures:"Izunna Stanislaus Okeke, Priscilla Yahemba Aondona, Amoge Chidinma Ogu, Eugene Echeweozo and Fabian Ifeanyichukwu Ezema"}],onlineFirstChaptersTotal:81},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:330,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:9,numberOfPublishedChapters:141,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:124,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:112,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:22,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:12,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. 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Dr. Koprowski has authored more than a hundred research papers with dozens in impact factor (IF) journals and has authored or co-authored six books. Additionally, he is the author of several national and international patents in the field of biomedical devices and imaging. 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Kendrekar, MSc, MBA, Ph.D., is currently a visiting scientist at the Lipid Nanostructure Laboratory, University of Central Lancashire, England. He previously worked as a post-doctoral fellow at the Ben-Gurion University of Negev, Israel; University of the Free State, South Africa; and Central University of Technology Bloemfontein, South Africa. He obtained his Ph.D. in Organic Chemistry from Nagaoka University of Technology, Japan. He has published more than seventy-four journal articles and attended several national and international conferences as speaker and chair. Dr. Kendrekar has received many international awards. He has several funded projects, namely, anti-malaria drug development, MRSA, and SARS-CoV-2 activity of curcumin and its formulations. He has filed four patents in collaboration with the University of Central Lancashire and Mayo Clinic Infectious Diseases. His present research includes organic synthesis, drug discovery and development, biochemistry, nanoscience, and nanotechnology.",institutionString:"Visiting Scientist at Lipid Nanostructures Laboratory, Centre for Smart Materials, School of Natural Sciences, University of Central Lancashire",institution:null},{id:"428125",title:"Dr.",name:"Vinayak",middleName:null,surname:"Adimule",slug:"vinayak-adimule",fullName:"Vinayak Adimule",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/428125/images/system/428125.jpg",biography:"Dr. Vinayak Adimule, MSc, Ph.D., is a professor and dean of R&D, Angadi Institute of Technology and Management, India. He has 15 years of research experience as a senior research scientist and associate research scientist in R&D organizations. He has published more than fifty research articles as well as several book chapters. He has two Indian patents and two international patents to his credit. Dr. Adimule has attended, chaired, and presented papers at national and international conferences. He is a guest editor for Topics in Catalysis and other journals. He is also an editorial board member, life member, and associate member for many international societies and research institutions. His research interests include nanoelectronics, material chemistry, artificial intelligence, sensors and actuators, bio-nanomaterials, and medicinal chemistry.",institutionString:"Angadi Institute of Technology and Management",institution:null},{id:"284317",title:"Prof.",name:"Kantharaju",middleName:null,surname:"Kamanna",slug:"kantharaju-kamanna",fullName:"Kantharaju Kamanna",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284317/images/21050_n.jpg",biography:"Prof. K. Kantharaju has received Bachelor of science (PCM), master of science (Organic Chemistry) and Doctor of Philosophy in Chemistry from Bangalore University. He worked as a Executive Research & Development @ Cadila Pharmaceuticals Ltd, Ahmedabad. He received DBT-postdoc fellow @ Molecular Biophysics Unit, Indian Institute of Science, Bangalore under the supervision of Prof. P. Balaram, later he moved to NIH-postdoc researcher at Drexel University College of Medicine, Philadelphia, USA, after his return from postdoc joined NITK-Surthakal as a Adhoc faculty at department of chemistry. Since from August 2013 working as a Associate Professor, and in 2016 promoted to Profeesor in the School of Basic Sciences: Department of Chemistry and having 20 years of teaching and research experiences.",institutionString:null,institution:{name:"Rani Channamma University, Belagavi",country:{name:"India"}}},{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/158492/images/system/158492.jpeg",biography:"Prof. Dr. Yusuf Tutar conducts his research at the Hamidiye Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Division of Biochemistry, University of Health Sciences, Turkey. He is also a faculty member in the Molecular Oncology Program. He obtained his MSc and Ph.D. at Oregon State University and Texas Tech University, respectively. He pursued his postdoctoral studies at Rutgers University Medical School and the National Institutes of Health (NIH/NIDDK), USA. His research focuses on biochemistry, biophysics, genetics, molecular biology, and molecular medicine with specialization in the fields of drug design, protein structure-function, protein folding, prions, microRNA, pseudogenes, molecular cancer, epigenetics, metabolites, proteomics, genomics, protein expression, and characterization by spectroscopic and calorimetric methods.",institutionString:"University of Health Sciences",institution:null},{id:"180528",title:"Dr.",name:"Hiroyuki",middleName:null,surname:"Kagechika",slug:"hiroyuki-kagechika",fullName:"Hiroyuki Kagechika",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180528/images/system/180528.jpg",biography:"Hiroyuki Kagechika received his bachelor’s degree and Ph.D. in Pharmaceutical Sciences from the University of Tokyo, Japan, where he served as an associate professor until 2004. He is currently a professor at the Institute of Biomaterials and Bioengineering (IBB), Tokyo Medical and Dental University (TMDU). From 2010 to 2012, he was the dean of the Graduate School of Biomedical Science. Since 2012, he has served as the vice dean of the Graduate School of Medical and Dental Sciences. He has been the director of the IBB since 2020. Dr. Kagechika’s major research interests are the medicinal chemistry of retinoids, vitamins D/K, and nuclear receptors. He has developed various compounds including a drug for acute promyelocytic leukemia.",institutionString:"Tokyo Medical and Dental University",institution:{name:"Tokyo Medical and Dental University",country:{name:"Japan"}}},{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94311/images/system/94311.jpeg",biography:"Martins Emeje obtained a BPharm with distinction from Ahmadu Bello University, Nigeria, and an MPharm and Ph.D. from the University of Nigeria (UNN), where he received the best Ph.D. award and was enlisted as UNN’s “Face of Research.” He established the first nanomedicine center in Nigeria and was the pioneer head of the intellectual property and technology transfer as well as the technology innovation and support center. Prof. Emeje’s several international fellowships include the prestigious Raman fellowship. He has published more than 150 articles and patents. He is also the head of R&D at NIPRD and holds a visiting professor position at Nnamdi Azikiwe University, Nigeria. He has a postgraduate certificate in Project Management from Walden University, Minnesota, as well as a professional teaching certificate and a World Bank certification in Public Procurement. Prof. Emeje was a national chairman of academic pharmacists in Nigeria and the 2021 winner of the May & Baker Nigeria Plc–sponsored prize for professional service in research and innovation.",institutionString:"National Institute for Pharmaceutical Research and Development",institution:{name:"National Institute for Pharmaceutical Research and Development",country:{name:"Nigeria"}}},{id:"436430",title:"Associate Prof.",name:"Mesut",middleName:null,surname:"Işık",slug:"mesut-isik",fullName:"Mesut Işık",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/436430/images/19686_n.jpg",biography:null,institutionString:null,institution:{name:"Bilecik University",country:{name:"Turkey"}}},{id:"268659",title:"Ms.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/268659/images/8143_n.jpg",biography:"Dr. Zhan received his undergraduate and graduate training in the fields of preventive medicine and epidemiology and statistics at the West China University of Medical Sciences in China during 1989 to 1999. He received his post-doctoral training in oncology and cancer proteomics for two years at the Cancer Research Institute of Human Medical University in China. In 2001, he went to the University of Tennessee Health Science Center (UTHSC) in USA, where he was a post-doctoral researcher and focused on mass spectrometry and cancer proteomics. Then, he was appointed as an Assistant Professor of Neurology, UTHSC in 2005. He moved to the Cleveland Clinic in USA as a Project Scientist/Staff in 2006 where he focused on the studies of eye disease proteomics and biomarkers. He returned to UTHSC as an Assistant Professor of Neurology in the end of 2007, engaging in proteomics and biomarker studies of lung diseases and brain tumors, and initiating the studies of predictive, preventive, and personalized medicine (PPPM) in cancer. In 2010, he was promoted to Associate Professor of Neurology, UTHSC. Currently, he is a Professor at Xiangya Hospital of Central South University in China, Fellow of Royal Society of Medicine (FRSM), the European EPMA National Representative in China, Regular Member of American Association for the Advancement of Science (AAAS), European Cooperation of Science and Technology (e-COST) grant evaluator, Associate Editors of BMC Genomics, BMC Medical Genomics, EPMA Journal, and Frontiers in Endocrinology, Executive Editor-in-Chief of Med One. He has\npublished 116 peer-reviewed research articles, 16 book chapters, 2 books, and 2 US patents. His current main research interest focuses on the studies of cancer proteomics and biomarkers, and the use of modern omics techniques and systems biology for PPPM in cancer, and on the development and use of 2DE-LC/MS for the large-scale study of human proteoforms.",institutionString:null,institution:{name:"Xiangya Hospital Central South University",country:{name:"China"}}},{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",biography:"Dr. Rizwan Ahmad is a University Professor and Coordinator, Quality and Development, College of Medicine, Imam Abdulrahman bin Faisal University, Saudi Arabia. Previously, he was Associate Professor of Human Function, Oman Medical College, Oman, and SBS University, Dehradun. Dr. Ahmad completed his education at Aligarh Muslim University, Aligarh. He has published several articles in peer-reviewed journals, chapters, and edited books. His area of specialization is free radical biochemistry and autoimmune diseases.",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",country:{name:"Saudi Arabia"}}},{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",biography:"Farid A. Badria, Ph.D., is the recipient of several awards, including The World Academy of Sciences (TWAS) Prize for Public Understanding of Science; the World Intellectual Property Organization (WIPO) Gold Medal for best invention; Outstanding Arab Scholar, Kuwait; and the Khwarizmi International Award, Iran. He has 250 publications, 12 books, 20 patents, and several marketed pharmaceutical products to his credit. He continues to lead research projects on developing new therapies for liver, skin disorders, and cancer. Dr. Badria was listed among the world’s top 2% of scientists in medicinal and biomolecular chemistry in 2019 and 2020. He is a member of the Arab Development Fund, Kuwait; International Cell Research Organization–United Nations Educational, Scientific and Cultural Organization (ICRO–UNESCO), Chile; and UNESCO Biotechnology France",institutionString:"Mansoura University",institution:{name:"Mansoura University",country:{name:"Egypt"}}},{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",biography:"Dr. Singh received a BPharm (2003) and MPharm (2005) from Panjab University, Chandigarh, India, and a Ph.D. (2013) from Punjab Technical University (PTU), Jalandhar, India. He has more than sixteen years of teaching experience and has supervised numerous postgraduate and Ph.D. students. He has to his credit more than seventy papers in SCI- and SCOPUS-indexed journals, fifty-five conference proceedings, four books, six Best Paper Awards, and five projects from different government agencies. He is currently an editorial board member of eight international journals and a reviewer for more than fifty scientific journals. He received Top Reviewer and Excellent Peer Reviewer Awards from Publons in 2016 and 2017, respectively. He is also on the panel of The International Reviewer for reviewing research proposals for grants from the Royal Society. He also serves as a Publons Academy mentor and Bentham brand ambassador.",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",country:{name:"India"}}},{id:"142388",title:"Dr.",name:"Thiago",middleName:"Gomes",surname:"Gomes Heck",slug:"thiago-gomes-heck",fullName:"Thiago Gomes Heck",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/142388/images/7259_n.jpg",biography:null,institutionString:null,institution:{name:"Universidade Regional do Noroeste do Estado do Rio Grande do Sul",country:{name:"Brazil"}}},{id:"336273",title:"Assistant Prof.",name:"Janja",middleName:null,surname:"Zupan",slug:"janja-zupan",fullName:"Janja Zupan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/336273/images/14853_n.jpeg",biography:"Janja Zupan graduated in 2005 at the Department of Clinical Biochemistry (superviser prof. dr. Janja Marc) in the field of genetics of osteoporosis. Since November 2009 she is working as a Teaching Assistant at the Faculty of Pharmacy, Department of Clinical Biochemistry. In 2011 she completed part of her research and PhD work at Institute of Genetics and Molecular Medicine, University of Edinburgh. She finished her PhD entitled The influence of the proinflammatory cytokines on the RANK/RANKL/OPG in bone tissue of osteoporotic and osteoarthritic patients in 2012. From 2014-2016 she worked at the Institute of Biomedical Sciences, University of Aberdeen as a postdoctoral research fellow on UK Arthritis research project where she gained knowledge in mesenchymal stem cells and regenerative medicine. She returned back to University of Ljubljana, Faculty of Pharmacy in 2016. She is currently leading project entitled Mesenchymal stem cells-the keepers of tissue endogenous regenerative capacity facing up to aging of the musculoskeletal system funded by Slovenian Research Agency.",institutionString:null,institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"357453",title:"Dr.",name:"Radheshyam",middleName:null,surname:"Maurya",slug:"radheshyam-maurya",fullName:"Radheshyam Maurya",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/357453/images/16535_n.jpg",biography:null,institutionString:null,institution:{name:"University of Hyderabad",country:{name:"India"}}},{id:"418340",title:"Dr.",name:"Jyotirmoi",middleName:null,surname:"Aich",slug:"jyotirmoi-aich",fullName:"Jyotirmoi Aich",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038Ugi5QAC/Profile_Picture_2022-04-15T07:48:28.png",biography:"Biotechnologist with 15 years of research including 6 years of teaching experience. Demonstrated record of scientific achievements through consistent publication record (H index = 13, with 874 citations) in high impact journals such as Nature Communications, Oncotarget, Annals of Oncology, PNAS, and AJRCCM, etc. Strong research professional with a post-doctorate from ACTREC where I gained experimental oncology experience in clinical settings and a doctorate from IGIB where I gained expertise in asthma pathophysiology. A well-trained biotechnologist with diverse experience on the bench across different research themes ranging from asthma to cancer and other infectious diseases. An individual with a strong commitment and innovative mindset. Have the ability to work on diverse projects such as regenerative and molecular medicine with an overall mindset of improving healthcare.",institutionString:"DY Patil Deemed to Be University",institution:null},{id:"349288",title:"Prof.",name:"Soumya",middleName:null,surname:"Basu",slug:"soumya-basu",fullName:"Soumya Basu",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035QxIDQA0/Profile_Picture_2022-04-15T07:47:01.jpg",biography:"Soumya Basu, Ph.D., is currently working as an Associate Professor at Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India. With 16+ years of trans-disciplinary research experience in Drug Design, development, and pre-clinical validation; 20+ research article publications in journals of repute, 9+ years of teaching experience, trained with cross-disciplinary education, Dr. Basu is a life-long learner and always thrives for new challenges.\r\nHer research area is the design and synthesis of small molecule partial agonists of PPAR-γ in lung cancer. She is also using artificial intelligence and deep learning methods to understand the exosomal miRNA’s role in cancer metastasis. Dr. Basu is the recipient of many awards including the Early Career Research Award from the Department of Science and Technology, Govt. of India. She is a reviewer of many journals like Molecular Biology Reports, Frontiers in Oncology, RSC Advances, PLOS ONE, Journal of Biomolecular Structure & Dynamics, Journal of Molecular Graphics and Modelling, etc. She has edited and authored/co-authored 21 journal papers, 3 book chapters, and 15 abstracts. She is a Board of Studies member at her university. She is a life member of 'The Cytometry Society”-in India and 'All India Cell Biology Society”- in India.",institutionString:"Dr. D.Y. Patil Vidyapeeth, Pune",institution:{name:"Dr. D.Y. Patil Vidyapeeth, Pune",country:{name:"India"}}},{id:"354817",title:"Dr.",name:"Anubhab",middleName:null,surname:"Mukherjee",slug:"anubhab-mukherjee",fullName:"Anubhab Mukherjee",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y0000365PbRQAU/ProfilePicture%202022-04-15%2005%3A11%3A18.480",biography:"A former member of Laboratory of Nanomedicine, Brigham and Women’s Hospital, Harvard University, Boston, USA, Dr. Anubhab Mukherjee is an ardent votary of science who strives to make an impact in the lives of those afflicted with cancer and other chronic/acute ailments. He completed his Ph.D. from CSIR-Indian Institute of Chemical Technology, Hyderabad, India, having been skilled with RNAi, liposomal drug delivery, preclinical cell and animal studies. He pursued post-doctoral research at College of Pharmacy, Health Science Center, Texas A & M University and was involved in another postdoctoral research at Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute, Santa Monica, California. In 2015, he worked in Harvard-MIT Health Sciences & Technology as a visiting scientist. He has substantial experience in nanotechnology-based formulation development and successfully served various Indian organizations to develop pharmaceuticals and nutraceutical products. He is an inventor in many US patents and an author in many peer-reviewed articles, book chapters and books published in various media of international repute. Dr. Mukherjee is currently serving as Principal Scientist, R&D at Esperer Onco Nutrition (EON) Pvt. Ltd. and heads the Hyderabad R&D center of the organization.",institutionString:"Esperer Onco Nutrition Pvt Ltd.",institution:null},{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/319365/images/system/319365.png",biography:"Manash K. Paul is a Principal Investigator and Scientist at the University of California Los Angeles. He has contributed significantly to the fields of stem cell biology, regenerative medicine, and lung cancer. His research focuses on various signaling processes involved in maintaining stem cell homeostasis during the injury-repair process, deciphering lung stem cell niche, pulmonary disease modeling, immuno-oncology, and drug discovery. He is currently investigating the role of extracellular vesicles in premalignant lung cell migration and detecting the metastatic phenotype of lung cancer via machine-learning-based analyses of exosomal signatures. Dr. Paul has published in more than fifty peer-reviewed international journals and is highly cited. He is the recipient of many awards, including the UCLA Vice Chancellor’s award, a senior member of the Institute of Electrical and Electronics Engineers (IEEE), and an editorial board member for several international journals.",institutionString:"University of California Los Angeles",institution:{name:"University of California Los Angeles",country:{name:"United States of America"}}},{id:"311457",title:"Dr.",name:"Júlia",middleName:null,surname:"Scherer Santos",slug:"julia-scherer-santos",fullName:"Júlia Scherer Santos",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311457/images/system/311457.jpg",biography:"Dr. Júlia Scherer Santos works in the areas of cosmetology, nanotechnology, pharmaceutical technology, beauty, and aesthetics. Dr. Santos also has experience as a professor of graduate courses. Graduated in Pharmacy, specialization in Cosmetology and Cosmeceuticals applied to aesthetics, specialization in Aesthetic and Cosmetic Health, and a doctorate in Pharmaceutical Nanotechnology. Teaching experience in Pharmacy and Aesthetics and Cosmetics courses. She works mainly on the following subjects: nanotechnology, cosmetology, pharmaceutical technology, aesthetics.",institutionString:"Universidade Federal de Juiz de Fora",institution:{name:"Universidade Federal de Juiz de Fora",country:{name:"Brazil"}}},{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",biography:"Dr. Kükürt graduated from Uludağ University in Turkey. He started his academic career as a Research Assistant in the Department of Biochemistry at Kafkas University. In 2019, he completed his Ph.D. program in the Department of Biochemistry at the Institute of Health Sciences. He is currently working at the Department of Biochemistry, Kafkas University. He has 27 published research articles in academic journals, 11 book chapters, and 37 papers. He took part in 10 academic projects. He served as a reviewer for many articles. He still serves as a member of the review board in many academic journals. He is currently working on the protective activity of phenolic compounds in disorders associated with oxidative stress and inflammation.",institutionString:null,institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"178366",title:"Dr.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",biography:"Volkan Gelen is a Physiology specialist who received his veterinary degree from Kafkas University in 2011. Between 2011-2015, he worked as an assistant at Atatürk University, Faculty of Veterinary Medicine, Department of Physiology. In 2016, he joined Kafkas University, Faculty of Veterinary Medicine, Department of Physiology as an assistant professor. Dr. Gelen has been engaged in various academic activities at Kafkas University since 2016. There he completed 5 projects and has 3 ongoing projects. He has 60 articles published in scientific journals and 20 poster presentations in scientific congresses. His research interests include physiology, endocrine system, cancer, diabetes, cardiovascular system diseases, and isolated organ bath system studies.",institutionString:"Kafkas University",institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"418963",title:"Dr.",name:"Augustine Ododo",middleName:"Augustine",surname:"Osagie",slug:"augustine-ododo-osagie",fullName:"Augustine Ododo Osagie",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/418963/images/16900_n.jpg",biography:"Born into the family of Osagie, a prince of the Benin Kingdom. I am currently an academic in the Department of Medical Biochemistry, University of Benin. 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She is a fellow member of the Royal Society of Chemistry UK and the American Chemical Society of the United States.",institutionString:"King Saud University",institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"49848",title:"Dr.",name:"Wen-Long",middleName:null,surname:"Hu",slug:"wen-long-hu",fullName:"Wen-Long Hu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49848/images/system/49848.jpg",biography:"Wen-Long Hu is Chief of the Division of Acupuncture, Department of Chinese Medicine at Kaohsiung Chang Gung Memorial Hospital, as well as an adjunct associate professor at Fooyin University and Kaohsiung Medical University. Wen-Long is President of Taiwan Traditional Chinese Medicine Medical Association. He has 28 years of experience in clinical practice in laser acupuncture therapy and 34 years in acupuncture. He is an invited speaker for lectures and workshops in laser acupuncture at many symposiums held by medical associations. He owns the patent for herbal preparation and producing, and for the supercritical fluid-treated needle. Dr. Hu has published three books, 12 book chapters, and more than 30 papers in reputed journals, besides serving as an editorial board member of repute.",institutionString:"Kaohsiung Chang Gung Memorial Hospital",institution:{name:"Kaohsiung Chang Gung Memorial Hospital",country:{name:"Taiwan"}}},{id:"298472",title:"Prof.",name:"Andrey V.",middleName:null,surname:"Grechko",slug:"andrey-v.-grechko",fullName:"Andrey V. Grechko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/298472/images/system/298472.png",biography:"Andrey Vyacheslavovich Grechko, Ph.D., Professor, is a Corresponding Member of the Russian Academy of Sciences. He graduated from the Semashko Moscow Medical Institute (Semashko National Research Institute of Public Health) with a degree in Medicine (1998), the Clinical Department of Dermatovenerology (2000), and received a second higher education in Psychology (2009). Professor A.V. Grechko held the position of Сhief Physician of the Central Clinical Hospital in Moscow. He worked as a professor at the faculty and was engaged in scientific research at the Medical University. Starting in 2013, he has been the initiator of the creation of the Federal Scientific and Clinical Center for Intensive Care and Rehabilitology, Moscow, Russian Federation, where he also serves as Director since 2015. He has many years of experience in research and teaching in various fields of medicine, is an author/co-author of more than 200 scientific publications, 13 patents, 15 medical books/chapters, including Chapter in Book «Metabolomics», IntechOpen, 2020 «Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology».",institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"199461",title:"Prof.",name:"Natalia V.",middleName:null,surname:"Beloborodova",slug:"natalia-v.-beloborodova",fullName:"Natalia V. Beloborodova",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/199461/images/system/199461.jpg",biography:'Natalia Vladimirovna Beloborodova was educated at the Pirogov Russian National Research Medical University, with a degree in pediatrics in 1980, a Ph.D. in 1987, and a specialization in Clinical Microbiology from First Moscow State Medical University in 2004. She has been a Professor since 1996. Currently, she is the Head of the Laboratory of Metabolism, a division of the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russian Federation. N.V. Beloborodova has many years of clinical experience in the field of intensive care and surgery. She studies infectious complications and sepsis. She initiated a series of interdisciplinary clinical and experimental studies based on the concept of integrating human metabolism and its microbiota. Her scientific achievements are widely known: she is the recipient of the Marie E. Coates Award \\"Best lecturer-scientist\\" Gustafsson Fund, Karolinska Institutes, Stockholm, Sweden, and the International Sepsis Forum Award, Pasteur Institute, Paris, France (2014), etc. Professor N.V. Beloborodova wrote 210 papers, five books, 10 chapters and has edited four books.',institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"354260",title:"Ph.D.",name:"Tércio Elyan",middleName:"Azevedo",surname:"Azevedo Martins",slug:"tercio-elyan-azevedo-martins",fullName:"Tércio Elyan Azevedo Martins",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/354260/images/16241_n.jpg",biography:"Graduated in Pharmacy from the Federal University of Ceará with the modality in Industrial Pharmacy, Specialist in Production and Control of Medicines from the University of São Paulo (USP), Master in Pharmaceuticals and Medicines from the University of São Paulo (USP) and Doctor of Science in the program of Pharmaceuticals and Medicines by the University of São Paulo. Professor at Universidade Paulista (UNIP) in the areas of chemistry, cosmetology and trichology. Assistant Coordinator of the Higher Course in Aesthetic and Cosmetic Technology at Universidade Paulista Campus Chácara Santo Antônio. Experience in the Pharmacy area, with emphasis on Pharmacotechnics, Pharmaceutical Technology, Research and Development of Cosmetics, acting mainly on topics such as cosmetology, antioxidant activity, aesthetics, photoprotection, cyclodextrin and thermal analysis.",institutionString:null,institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"334285",title:"Ph.D. Student",name:"Sameer",middleName:"Kumar",surname:"Jagirdar",slug:"sameer-jagirdar",fullName:"Sameer Jagirdar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334285/images/14691_n.jpg",biography:"I\\'m a graduate student at the center for biosystems science and engineering at the Indian Institute of Science, Bangalore, India. I am interested in studying host-pathogen interactions at the biomaterial interface.",institutionString:null,institution:{name:"Indian Institute of Science Bangalore",country:{name:"India"}}},{id:"329248",title:"Dr.",name:"Md. Faheem",middleName:null,surname:"Haider",slug:"md.-faheem-haider",fullName:"Md. Faheem Haider",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329248/images/system/329248.jpg",biography:"Dr. Md. Faheem Haider completed his BPharm in 2012 at Integral University, Lucknow, India. In 2014, he completed his MPharm with specialization in Pharmaceutics at Babasaheb Bhimrao Ambedkar University, Lucknow, India. He received his Ph.D. degree from Jamia Hamdard University, New Delhi, India, in 2018. He was selected for the GPAT six times and his best All India Rank was 34. Currently, he is an assistant professor at Integral University. Previously he was an assistant professor at IIMT University, Meerut, India. He has experience teaching DPharm, Pharm.D, BPharm, and MPharm students. He has more than five publications in reputed journals to his credit. Dr. Faheem’s research area is the development and characterization of nanoformulation for the delivery of drugs to various organs.",institutionString:"Integral University",institution:{name:"Integral University",country:{name:"India"}}},{id:"329795",title:"Dr.",name:"Mohd Aftab",middleName:"Aftab",surname:"Siddiqui",slug:"mohd-aftab-siddiqui",fullName:"Mohd Aftab Siddiqui",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329795/images/system/329795.png",biography:"Dr. Mohd Aftab Siddiqui is an assistant professor in the Faculty of Pharmacy, Integral University, Lucknow, India, where he obtained a Ph.D. in Pharmacology in 2020. He also obtained a BPharm and MPharm from the same university in 2013 and 2015, respectively. His area of research is the pharmacological screening of herbal drugs/natural products in liver cancer and cardiac diseases. He is a member of many professional bodies and has guided many MPharm and PharmD research projects. Dr. Siddiqui has many national and international publications and one German patent to his credit.",institutionString:"Integral University",institution:null}]}},subseries:{item:{id:"22",type:"subseries",title:"Applied Intelligence",keywords:"Machine Learning, Intelligence Algorithms, Data Science, Artificial Intelligence, Applications on Applied Intelligence",scope:"This field is the key in the current industrial revolution (Industry 4.0), where the new models and developments are based on the knowledge generation on applied intelligence. The motor of the society is the industry and the research of this topic has to be empowered in order to increase and improve the quality of our lives.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/22.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11418,editor:{id:"27170",title:"Prof.",name:"Carlos",middleName:"M.",surname:"Travieso-Gonzalez",slug:"carlos-travieso-gonzalez",fullName:"Carlos Travieso-Gonzalez",profilePictureURL:"https://mts.intechopen.com/storage/users/27170/images/system/27170.jpeg",biography:"Carlos M. Travieso-González received his MSc degree in Telecommunication Engineering at Polytechnic University of Catalonia (UPC), Spain in 1997, and his Ph.D. degree in 2002 at the University of Las Palmas de Gran Canaria (ULPGC-Spain). He is a full professor of signal processing and pattern recognition and is head of the Signals and Communications Department at ULPGC, teaching from 2001 on subjects on signal processing and learning theory. His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. He is the founder of The IEEE IWOBI conference series and the president of its Steering Committee, as well as the founder of both the InnoEducaTIC and APPIS conference series. He is an evaluator of project proposals for the European Union (H2020), Medical Research Council (MRC, UK), Spanish Government (ANECA, Spain), Research National Agency (ANR, France), DAAD (Germany), Argentinian Government, and the Colombian Institutions. He has been a reviewer in different indexed international journals (<70) and conferences (<250) since 2001. He has been a member of the IASTED Technical Committee on Image Processing from 2007 and a member of the IASTED Technical Committee on Artificial Intelligence and Expert Systems from 2011. \n\nHe has held the general chair position for the following: ACM-APPIS (2020, 2021), IEEE-IWOBI (2019, 2020 and 2020), A PPIS (2018, 2019), IEEE-IWOBI (2014, 2015, 2017, 2018), InnoEducaTIC (2014, 2017), IEEE-INES (2013), NoLISP (2011), JRBP (2012), and IEEE-ICCST (2005)\n\nHe is an associate editor of the Computational Intelligence and Neuroscience Journal (Hindawi – Q2 JCR-ISI). He was vice dean from 2004 to 2010 in the Higher Technical School of Telecommunication Engineers at ULPGC and the vice dean of Graduate and Postgraduate Studies from March 2013 to November 2017. 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