Satellite bus subsystems decomposition and potential KOSS.
\r\n\t
",isbn:"978-1-83881-111-2",printIsbn:"978-1-83880-992-8",pdfIsbn:"978-1-83881-112-9",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"acb2875b3bfc189c9881a9b44b6a5184",bookSignature:"Dr. Abdo Abou Jaoudé",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11865.jpg",keywords:"Linear Operators, Normal Operators, Spectral Theorem, Applications, Differential Operators, Integral Operators, Functional Calculus, Complex Variables, Complex Analysis, Theory, Recent Advances, Latest Trends",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 13th 2022",dateEndSecondStepPublish:"June 21st 2022",dateEndThirdStepPublish:"August 20th 2022",dateEndFourthStepPublish:"November 8th 2022",dateEndFifthStepPublish:"January 7th 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"15 days",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Abdo Abou Jaoudé is a pioneering Associate Professor of Mathematics and Statistics at Notre Dame University-Louaizé. He holds two PhDs in Mathematics and Prognostics from the Lebanese University and Aix-Marseille University. His research interests are in the field of mathematics.",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"248271",title:"Dr.",name:"Abdo",middleName:null,surname:"Abou Jaoudé",slug:"abdo-abou-jaoude",fullName:"Abdo Abou Jaoudé",profilePictureURL:"https://mts.intechopen.com/storage/users/248271/images/system/248271.jpg",biography:"Abdo Abou Jaoudé has been teaching for many years and has a passion for researching and teaching mathematics. He is currently an Associate Professor of Mathematics and Statistics at Notre Dame University-Louaizé (NDU), Lebanon. He holds a BSc and an MSc in Computer Science from NDU, and three PhDs in Applied Mathematics, Computer Science, and Applied Statistics and Probability, all from Bircham International University through a distance learning program. He also holds two PhDs in Mathematics and Prognostics from the Lebanese University, Lebanon, and Aix-Marseille University, France. Dr. Abou Jaoudé's broad research interests are in the field of applied mathematics. He has published twenty-three international journal articles and six contributions to conference proceedings, in addition to seven books on prognostics, pure and applied mathematics, and computer science.",institutionString:"Notre Dame University - Louaize",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"4",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"Notre Dame University – Louaize",institutionURL:null,country:{name:"Lebanon"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"15",title:"Mathematics",slug:"mathematics"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"252211",firstName:"Sara",lastName:"Debeuc",middleName:null,title:"Ms.",imageUrl:"https://mts.intechopen.com/storage/users/252211/images/7239_n.png",email:"sara.d@intechopen.com",biography:"As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"314",title:"Regenerative Medicine and Tissue Engineering",subtitle:"Cells and Biomaterials",isOpenForSubmission:!1,hash:"bb67e80e480c86bb8315458012d65686",slug:"regenerative-medicine-and-tissue-engineering-cells-and-biomaterials",bookSignature:"Daniel Eberli",coverURL:"https://cdn.intechopen.com/books/images_new/314.jpg",editedByType:"Edited by",editors:[{id:"6495",title:"Dr.",name:"Daniel",surname:"Eberli",slug:"daniel-eberli",fullName:"Daniel Eberli"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"57",title:"Physics and Applications of Graphene",subtitle:"Experiments",isOpenForSubmission:!1,hash:"0e6622a71cf4f02f45bfdd5691e1189a",slug:"physics-and-applications-of-graphene-experiments",bookSignature:"Sergey Mikhailov",coverURL:"https://cdn.intechopen.com/books/images_new/57.jpg",editedByType:"Edited by",editors:[{id:"16042",title:"Dr.",name:"Sergey",surname:"Mikhailov",slug:"sergey-mikhailov",fullName:"Sergey Mikhailov"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1373",title:"Ionic Liquids",subtitle:"Applications and Perspectives",isOpenForSubmission:!1,hash:"5e9ae5ae9167cde4b344e499a792c41c",slug:"ionic-liquids-applications-and-perspectives",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/1373.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2270",title:"Fourier Transform",subtitle:"Materials Analysis",isOpenForSubmission:!1,hash:"5e094b066da527193e878e160b4772af",slug:"fourier-transform-materials-analysis",bookSignature:"Salih Mohammed Salih",coverURL:"https://cdn.intechopen.com/books/images_new/2270.jpg",editedByType:"Edited by",editors:[{id:"111691",title:"Dr.Ing.",name:"Salih",surname:"Salih",slug:"salih-salih",fullName:"Salih Salih"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"872",title:"Organic Pollutants Ten Years After the Stockholm Convention",subtitle:"Environmental and Analytical Update",isOpenForSubmission:!1,hash:"f01dc7077e1d23f3d8f5454985cafa0a",slug:"organic-pollutants-ten-years-after-the-stockholm-convention-environmental-and-analytical-update",bookSignature:"Tomasz Puzyn and Aleksandra Mostrag-Szlichtyng",coverURL:"https://cdn.intechopen.com/books/images_new/872.jpg",editedByType:"Edited by",editors:[{id:"84887",title:"Dr.",name:"Tomasz",surname:"Puzyn",slug:"tomasz-puzyn",fullName:"Tomasz Puzyn"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"72147",title:"Future Satellite System Architectures and Practical Design Issues: An Overview",doi:"10.5772/intechopen.92308",slug:"future-satellite-system-architectures-and-practical-design-issues-an-overview",body:'Typical commercial and civilian satellite systems take about 2–3years to build and launch [1, 2, 3, 4], while military systems take between 7 and 10 years [5, 6]. A typical production flow for assembling and launching of a space vehicle is presented in Ref. [6] and redrawn in Figure 1 as introduction steps for better understanding of the design, build and launch of a satellite system. This chapter focuses on practical design issues for satellite Bus’ and mission PL’s system/subsystem components builds, and corresponding interface-design’s challenges associated with satellite Bus integration, mission PL integration, and satellite system integration. A survey of existing commercial, civilian and military satellite systems revealed that a typical satellite Bus includes the following modular components [7, 8, 9, 10, 11, 12, 13, 14, 15, 16]:
Bus Subsystem 1—Bus TX/RX Antenna Subsystem (BAS): Provide Bus’s Receive (RX)/Transmit (TX) antennas and associated Bus’s antenna beam control functions;
Bus Subsystem 2—Bus Communication RF Front-End-Back-End Subsystem (BCom-RFS): Provide Low Noise Amplifier (LNA), High Power Amplifier (HPA), satellite Bus Down/Up Radio Frequency (RF)-to-Intermediate Frequency (IF) conversion, and Analog-to-Digital/Digital-to-Analog conversion functions—Note that typical HPAs are Traveling Wave Tube Amplifier (TWTA) and Solid State Power Amplifier (SSPA), and some advanced satellite transponders use Linearized TWTA (L-TWTA) or L-SSPA in the RF Back-End Subsystem;
Bus Subsystem 3—Bus Command & Data Handling Subsystem (BC&DHS): On-board computer that interfaces with all Bus components;
Bus Subsystem 4—Bus Telemetry-Tracking & Command Subsystem (BTT&CS): Process uplink satellite Bus command data, perform satellite tracking functions and provide downlink Bus telemetry reporting satellite Bus’s heath and conditions;
Bus Subsystem 5—Bus Electrical Power Subsystem (BEPS): Provide and regulate Bus power;
Bus Subsystem 6—Bus Thermal Control Subsystem (BTCS): Maintain Bus’ thermal environments;
Bus Subsystem 7—Bus Altitude and Determination Control Subsystem (BADCS): Provide satellite stabilization, control and positioning;
Bus Subsystem 8—Bus Propulsion Subsystem (BPS): Provide propulsion functions for satellite maneuvering;
Bus Subsystem 9—Bus Communication Security Subsystem (BCOMSEC): Provide Bus data encryption and decryption functions to protect data from intruders. Typically, BCOMSEC is tightly coupled with BTT&CS;
Bus Subsystem 10—Bus Structure & Mechanism Subsystem (BS&MS): Provide structure and mechanism to mount all satellite Bus components.
A typical satellite system production flow (redrawn from [
Similarly, our survey also revealed that a typical mission PL consists of the following modular components [7, 8, 9, 10, 11, 12, 13, 14, 15, 16]:
PL Subsystem 1—PL PAS: Similar to BPAS but for mission PL;
PL Subsystem 2—PL Com-RFS: Similar to BCom-RFS but for mission PL;
PL Subsystem 3—PL Digital Processing Subsystem (PDPS): Provide mission specific processing functions. For SATCOM missions, specific processing functions can be dynamic resources control, channelization processing, etc. For PNT missions, the functions can be time transfer processing functions. For imaging/sensing missions, the functions can be image preprocessing functions;
PL Subsystem 4—PL C&DHS: Similar to BC&DHS but for mission PL;
PL Subsystem 5—PL TT&CS: Similar to BTT&CS but for mission PL;
PL Subsystem 6—PL EPS: Existing PLs use power supply from satellite BEPS;
PL Subsystem 7—PL TCS: Maintain PL’s thermal environments;
PL Subsystem 8—PL ADCS: Existing PLs use ADCS from the satellite BADCS;
PL Subsystem 9—PL PS:: Existing mission PLs use PS from the satellite BPS;
PL Subsystem 10—PL COMSEC: Similar to BCOMSEC but for mission PL;
PL Subsystem 11—PL Frequency & Timing Subsystem (PFTS): Provide reference frequency and timing functions to meet specific mission requirements;
PL Subsystem 12—PL Transmission Security Subsystem (TRANSEC): Provide security functions to combat unintentional and/or intentional Radio Frequency Interference (RFI) (e.g., frequency hopping/de-hopping, frequency spreading/de-spreading);
PL Subsystem 13—PL Specific Mission Suite (SMS): Provide specific mission PL processing functions depending on whether the mission is Satellite Communications (SATCOM) mission or Position Navigation and Timing (PNT) mission or Imaging/Sensing mission [7, 8, 9, 10, 11, 12, 13, 14, 15, 16];
PL Subsystem 14—PL Structure & Mechanism Subsystem (BS&MS): Provide structure and mechanism to mount all mission PL components.
In practice, the above satellite Bus modular components can be found in the following typical satellite Busses [7, 11, 14]:
Loral Satellite Bus 1300 or Loral 1300
Lockheed Martin (LM) A2100A/AX-Land Mobile/AX-High Power
Boeing 702HP/HP-GEM/MP/702SP and 502.
For achieving optimum weight and power, existing satellite Bus and mission PL are tightly coupled together with customized interface design. The industry trends for the design and build of future satellite systems are moving toward OSA using MOSA principles, in which the satellite Bus is loosely coupled with the mission PL using “Open” and widely accepted interface standards. The key communication linkage between a satellite Bus and a mission PL is the communication data Bus. Currently, majority of satellite Busses employ the standard 1553 data Bus for data communications among Bus components, and between the satellite Bus and mission PL components. The communications over 1553 data Bus is limited to 1 Mega bit per second (Mbps). Recently, there was an advanced development effort that was funded by the U.S DOD to develop new 1553 standards called 1553 Enhanced Bit Rate (EBR–1553) increasing the speed to 10 MB/s [17]. The EBR-1553 requires a star/hub topology to provide the higher data rate and additional components to implement the architecture. For data rates larger than 10 Mbps, space industry trend is moving toward SpaceWire data Bus that was recently developed in Europe for use in commercial satellites and scientific spacecraft [18].
The objective of this chapter is three-fold: (1) Provides an overview of existing modular satellite Bus, mission PL architectures and related communication data Busses, (2) Discusses future trends on the modular and open design and build of satellite Bus and mission payload using MOSA principles, and (3) Addresses the practical design challenges associated with “Modular” and “Open” design for future satellite Bus and mission PL. The chapter is organized as follow: (i) Section 2 describes existing modular satellite Bus and mission PL architectures and related communication data Busses; (ii) Section 3 presents industry view on “Open” and “Close” interfaces for connecting satellite system components and existing popular standards; (iii) Section 4 discusses the interface design challenges and provides an overview of MOSA and related DOD Guidance and assessment tools for MOSA implementation; (iv) Section 5 provides examples how to transition modular satellite Bus and mission PL architectures to modular-and-open architectures using MOSA implementation approach and tools in Section 4; and (v) Section 6 concludes the chapter with remarks on the benefits associated with the proposed approach.
Figure 2 describes an overview of existing satellite systems, consisting of a satellite Bus, a mission PL and a typical set of interfaces between the Bus and PL using a standard data Bus. A typical set of interfaces between the satellite Bus and a mission PL includes seven interface types, namely: (i) Physical & Mechanical Interface, (ii) Electrical/Power/Cable Interface, (iii) Grounding Interface, (iv) Software & Data Interface, (v) Electromagnetic Compatibility (EMC)/ Electromagnetic Interference (EMI)/Electromagnetic Pulse (EMP) and Electro Static Discharge (ESD) Interface, (vi) Thermal Interface, and (vii) Frequency & Timing (F&T) Interface. This section focuses on satellite Bus and mission PL architectures and the data interfaces between them. Subsections 2.1 and 2.2 describe existing satellite Bus and mission PL architectures along with related interfaces and industry standards, respectively. Subsection 2.3 discusses existing standard 1553 data Bus and the pushes from space industry moving toward military standard 1553-B data Bus (MIL-STD-1553-B) and high-data-rate SpaceWire data Bus.
Overview of existing satellite Systems using standard 1553 data bus.
As described in Section 1, existing satellite Bus architecture includes typical 10 modular components, namely, BAS, BComRFS, BC&DHS, BTT&CS, BEPS, BTCS, BADCS, BPS, BCOMSEC and BS&MS. A functional description for each of these modular Bus components is also described in Section 1. Figure 3 illustrates a notional block diagram for existing modular satellite Bus architecture. The figure shows that space industry has used the modular design concept to architect the satellite Bus, where common functions are group together and then isolate or separate from the other group of functions. As an example, BAS consists of a group of antenna components and control functions (e.g., antenna pointing, beamforming, etc.), which is separated and isolated from BComRFS. It is important to note that the figure also shows how these satellite Bus components are connected together, i.e., the lines with arrows connecting them. These lines represent the interfaces among the Bus components, where the interface can be any of the seven interface types described above. Below is a list of some of the existing interfaces and associated standards for existing satellite Bus based on National Aeronautical and Space Administration (NASA), European Space Agency (ESA), U.S. DOD and international Consultative Committee for Space Data System (CCSDS) standards [19, 20, 21, 22, 23, 24, 25, 26]:
Typical NASA Electrical/Power/Cable Interface Standards [19, 20]:
Satellite Bus shall protect its own electrical power system via overcurrent protection devices on its side of the interface.
Satellite Bus shall deliver a maximum transient current on any Power Feed Bus of 100% (that is, two times the steady state current) of the maximum steady-state current for no longer than 50 ms.
Bus Survival Heaters, which are elements of the Bus thermal subsystem, shall be required to have power to heat certain satellite Bus components during off-nominal scenarios when the BEPS power is not fully energized.
Typical U.S. DOD EMC/EMI/EMP/ESD Interface Standards [21]:
Power line conducted emissions for satellite Bus equipment shall meet the EMC interface specification specified in SMC Standard Handbook, SMC-S-008, Section 6, 6.01, 6.02, 6,03, 6.04, 6.05, 6.06, 6.07, and 6.08.
Power line conducted susceptibility for satellite Bus equipment shall meet the EMC interface specification specified in SMC Standard Handbook, SMC-S-008, Sections 6, 6.10, 6.11, 6.12, 6.13, 6.14, 6.15, 6.16, 6.17, 6.18 and 6.19.
ESD susceptibility for satellite Bus equipment shall meet the EMC interface specification specified in SMC Standard Handbook, SMC-S-008, Section 6, 6.43.
EMP susceptibility for satellite Bus equipment shall meet the EMC interface specification specified in SMC Standard Handbook, SMC-S-008, Section 6, 6.45.
Typical NASA Grounding Interface Standards [20, 22]:
Satellite Bus EPS should ground in a way that reduces introducing stray currents or ground loop currents into the satellite Bus components.
Satellite Bus ground interface shall follow NASA single-point ground or multiple-point ground architecture.
Typical NASA Thermal Interface Standards [19, 20]:
A conductive heat transfer of 15 W/m2 or 4 W shall be considered small enough to meet the intent of being thermally isolated.
Typical Software & Data Interface Standards [19, 20, 23, 24, 25, 26]:
Satellite Bus command and telemetry data formats shall be NASA Unified S-Band (USB)/CCSDS standards or U.S. DOD Space-Ground Link Subsystem (SGLS) standards. Note that (i) most of NASA and ESA standards are CCSDS compliance for interoperability purpose, and (ii) some military systems have both USB and SGLS capabilities.
Satellite Bus “Safe Mode” is a combined satellite Bus components hardware and software configuration that shall be designed to protect the components from possible internal or external harm while making minimal use of satellite Bus resources (e.g., power).
Satellite Command SAFE Mode shall be required to protect and preserve satellite Bus components under anomalous and resource constrained conditions.
Satellite Bus components shall respond to uplink commands from the Satellite Operation Center (SOC) to suspend and resume the transmission of the Components’ telemetry data. For commercial satellite systems, SOC can also control the mission PL.
Existing notional modular satellite bus architecture.
For military applications, majority of satellite Busses are usually designed using contractor’s custom designed interfaces and very tightly couple together to reduce weight, size and power. It is for this reason, current military satellite BTT&CS component also include the COMSEC component. For commercial applications, satellite developers are also concerned with weight, size and power reduction, but they are also concerned with component refresh and upgrade without redesigning the satellite Bus, hence commercial satellites tend to use modular Bus components and widely accepted interface standards to connect the internal Bus components. Industry views on the “open” and “close” interfaces will be addressed in Section 4.
As pointed out in Section 1, existing mission PL architecture consists of 14 modular components, but there are three PL components that rely on the satellite Bus’ design, namely, PL EPS, PL ADCS and PL PS. Therefore, the mission PL architecture usually has 11 modular components, including PL AS, PL Com-RFS, PDPS, PL C&DHS, PL TT&CS, PL TCS, PL COMSEC, PFTS, PL TRANSEC, PL SMS and PL S&MS. A functional description for each of these mission PL modular components is also provided in Section 1. Figure 4 presents a notional block diagram for existing modular mission PL architecture. Similar to the satellite Bus design, the space industry has also applied the modular design concept to architect the mission PL. Below is a list of some of the existing interfaces and associated standards for existing mission PL leveraged from NASA, ESA, U.S. DOD and international CCSDS standards [19, 20, 21, 22, 23, 24, 25, 26]:
Typical NASA Electrical/Power/Cable Interface Standards [19, 20]:
Sizing all components of the mission PL power harness, such as the wires, connectors, sockets, and pins to the peak power level shall be required by the mission PL equipment in addition to satellite Bus to prevent damage to the power harnessing.
PL Survival Heaters shall be required to have power to heat certain mission PL components during off-nominal scenarios when the BEPS power is not fully energized.
Typical U.S. DOD EMC/EMI/EMP/ESD Interface Standards [21]: Similar to satellite Bus discussed above but for mission PL.
Typical NASA Grounding Interface Standards [20, 22]: Similar to satellite Bus discussed above but for mission PL.
Typical NASA Thermal Interface Standards [19, 20]:
The mission PL thermal design should be decoupled from the satellite Bus at the mechanical interface between the satellite Bus and neighboring mission payload to the maximum practical extent.
A conductive heat transfer of 15 W/m2 or 4 W shall be considered small enough to meet the intent of being thermally isolated.
Typical Software & Data Interface Standards [19, 20, 23, 24, 25, 26]:
Mission PL command and telemetry data formats shall be NASA USB/CCSDS standards commercial applications or U.S. DOD SGLS standards for military applications. Some military systems have both USB and SGLS capabilities.
PL “Safe Mode” is a combined mission PL components hardware and software configuration that shall be designed to protect the PL components from possible internal or external harm while making minimal use of satellite Bus resources (e.g., power).
PL Command SAFE Mode shall be required to protect and preserve mission PL components under anomalous and resource constrained conditions.
Mission PL components shall respond to uplink commands from Mission Control Center (MCC) to suspend and resume the transmission of the mission PL components.
Mission PL shall be responsible for on-board mission data storage capabilities.
Existing notional modular Mission payload architecture.
For most commercial applications, the MCC can be merged with the SOC, and the mission PL TT&CS (PTT&CS) and PL CD&HS (PCD&HS) components can be incorporated into satellite (i) Bus TT&C (BTT&CS) and (ii) Bus CD&HS (BCD&HS) components, respectively. Similar to the satellite Bus interfaces design, for military applications, the mission PL components are tightly coupled using contractor’s custom designed interfaces. For commercial applications, the mission PL components are loosely coupled using widely accepted open interfaces.
Subsections 2.3.1 and 2.3.2 provide an overview of standard 1553 and SpaceWire communication data Busses, respectively.
Existing commercial, civilian and military satellite data Busses have been using Military Standard 1553B (MIL-STD-1553B) data Bus for communications among satellite Bus and mission PL components. Figure 5 describes a typical MIL-STD-1553B System [17, 27, 28]. This figure uses MIL-STD-1553B terminologies: (i) the Bus Controller (BC) is considered as an Intelligent Terminal (IT) that is located in the satellite mission computer, which is usually referred to as a Satellite Bus C&DH component, and (ii) Remote Terminal (RT) is considered as a slave terminal that is located in satellite platform components, which can be located in any satellite Bus or mission PL components.
Typical civilian and commercial MIL-STD-1553B satellite Systems.
Figure 5 shows a typical commercial satellite system with RTs located in both satellite Bus and mission PL components. As an Example, the RTs located in satellite components are BAS, BADCS, BTCS and BTT&CS; and RTs located in the mission PL components are PAS, PTCS, PDPS, PTRANSEC, and PFTS. For military applications, the Mission Computer (MC) can be located in both satellite Bus and mission PL, where the MC in the satellite Bus is responsible for all control functions associated with the satellite operations and MC in the mission PL is responsible for all control functions related to the mission PL operations.
SpaceWire (SpW) is an industry standard with protocol derived from IEEE-1355 and ECSS-E50-12C managing by the international SpW working Group [18, 29, 30]. The SpW standard is a self-managing serial protocol that provides a high-speed data rates from 2 to 400 Mbps, and low power serial interface using LVDS1 Drivers with distances up to 30 feet while offering a flexible simple user interface. Figure 6 illustrates typical uses of SpW data Bus with a PCD&HS, a SpW Router and SpW cables for connecting mission PL components. Some examples of existing satellite programs employed SpaceWire standard are: TacSat (part of the U.S. Operationally Responsive Space Program), NASA Lunar Reconnaissance Orbiter (Orbiting the Moon taking high resolution images), ESA Sentinel-3 (a pair of satellites providing operational Earth observation services using optical and microwave instruments), and Japanese NEC NEXTTAR (one of the first spacecraft designed using SpW for all of its onboard communications).
Typical civilian and commercial SpaceWire satellite Systems.
Figure 7 presents the space industry view on open and close interface design. This view separates the interface design into two categories, namely, Contractor Proprietary Interface and Contractor Non-Proprietary Interface. Under this view, the interface standards are then classified into two categories, namely, Preferred and Non-Preferred Interface Standards. Based on this view, Section 3.1 defines open interface design, and Section 3.2 defines close interface design. Section 3.3 provides a list of existing popular open standards widely accepted by space industry.
Industry view on open and closed interfaces design.
From Figure 7, the open interface design falls into the contractor non-proprietary design category. For the interface design to be open, the interface design shall not be contractor proprietary and that the interface shall use either popular open interface standards widely accepted by space industry or open interface standards with little market support and narrowly used by space industry. Thus, a popular open interface design is a non-proprietary design that uses popular open interface standard that is widely used by space industry. The benefits of open interface design for the satellite buyers are (i) improving competition allowing various space vendors (or contractor) to build open satellite Bus and mission PL subsystem components, (ii) ease of refresh and technology upgrade allowing to swap subsystem components without impacting the overall system, (iii) ease of adapting to new requirements and operational threats, (iv) incorporating innovation by allowing operational flexibility to configure and reconfigure a mission PL quickly to meet rapidly changing operational requirements, (v) enabling cost saving and cost avoidance during the design and sustainment phases by reusing technology and Software/Hardware/Middleware (SW/HW/MW) components, and using existing standardized HW/SW/MW parts and modules, and (vi) improving interoperability where severable HW/SW/MW modules can be changed independently.
As shown in Figure 7, the close interface design shall fall into contractor proprietary category. For an interface design to be close, it shall be contractor proprietary and that the interface shall use either close interface standards with little market support narrowly used by space industry or popular closed interface standards widely used by space industry. Thus, a popular close interface design is a contractor proprietary design that uses popular closed interface that is widely used by space industry. The key benefits of close interface design are the potential reduction of weight, size, power and manufacturing cost.
Based on Figure 7, the criteria for popular open standards are (i) publicly available and widely used by both satellite Bus and mission PL vendors, (ii) community and/or industry consensus-based that are matured and stable, and (iii) technically adequate for all future commercial, civilian and military satellite systems. Following is a list of current popular standard organizations and widely adopted open standards [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]:
Consultative Committee for Space Data Systems (CCSDS) Standards: is a multi-national forum for the development of communications and data systems standards for spaceflight. The goal is to enhance governmental and commercial interoperability and cross-support, while also reducing risk, development time and project costs.
AIAA Space Plug-and-play Avionics (SPA) Standard: SPA is a set of AIAA standards developed for spacecraft platform, subsystem, and component (including payload) developers for integrating plug-and-play characteristics into spacecraft structures, avionics, and hardware and software components to promote their rapid integration. The SPA community anticipates adding protocols (e.g., Ethernet as SPA-E) as the PnP capabilities are normalized.
MIL-STD-1553 Standard: is a military standard published by the United States Department of Defense that defines the mechanical, electrical, and functional characteristics of a serial data Bus.
SpaceWire Standard: is a spacecraft communication network standard based in part on the IEEE 1355 standard of communications. It is coordinated by the European Space Agency (ESA) in collaboration with international space agencies including NASA, Japanese Space Agency (JAXA) and Russian Federal Space Agency (RKA).
NASA/SMC/Aerospace Hosted Payload Interface Design (HPID): this design guideline provides a prospective Instrument Developer with technical recommendations to assist them in designing an Instrument or Payload that may be flown as a hosted payload on commercial satellites flown in Low Earth Orbit (LEO), or Geostationary Earth Orbit (GEO).
SQL for databases specified in ANSI ISO/IEC 9075–1, ISO/IEC 9075–2, ISO/IEC 9075–3, ISO/IEC 9075–4, ISO/IEC 9075–5.
HTML for presentation layer specified in XML 1.0 www.webstandards.org.
XML for data transfer.
Web Services for remote system calls.
U.S. Space and Missile Systems Center (SMC) approved a project for developing Common Payload Interface Specification (CoPaIS) standard for satellite-to-payload Command and Data Handling (C&DH) interface intended for all future SMC procured medium to large satellites [31].
Other popular standards: MIL-STD-1553B, CAN Bus, RS-422 (TTC-B01 Protocol)/EIA/TIA-422, RS-422 (PC-Protocol).
This section addresses the design challenges and is divided into four subsections, including: (i) Subsection 4.1 discusses interface design and practical design issues; (ii) Subsection 4.2 introduces MOSA concept; (iii) Subsection 4.3 presents DOD MOSA guidance and the U.S. Naval Open Architecture (NOA); and (iv) Subsection 4.4 discusses MOSA tools and approach for MOSA implementation that addresses the design issues identified in Subsection 4.1.
The interfaces between satellite subsystem components can be SW, HW or MW interfaces. The design and build of these interfaces are well incorporated into any satellite subsystem components “Design Product” and associated “Design Process”.
The Design Product includes System Architecture, Interface Product, Independent Verification and Validation (IV&V) Test Plan, Schedule, Design Approach, Acceptance Criteria, and System-Built Product.
For MOSA, the Design Process is expected to incorporate MOSA into: Architecture Process, Interface Management, IV&V Process, and System Engineering and Integration (SE&I) Process. The Interface Product and its open interface design using MOSA along with the Interface Management are the key challenges in the development of open-and-modular satellite systems. The key design challenges for the design and build of open-and-modular satellite systems are:
Challenge 1: Determination of Key Open Subsystem (KOSS): This is also known as KOSS Selection. Ideally, all modular subsystem components should be made open. But this is not practical, because some interfaces need to be customized using close interface design due to weight, size and power reduction requirements. The key challenge here is to identify a set of criteria that can be used for KOSS selection. Subsections 4.3 and 4.4 will address this challenge.
Challenge 2: Designation of Key Interfaces for the Selected KOSS: Satellite system designers need to identify a subset of selected set of KOSS components that can be designated as key interfaces. The key challenge here is to identify a business case for the designated key interfaces. Subsections 4.3 and 4.4 will describe selection criteria and tool to address this challenge.
Challenge 3: Selection of Open Standards for the Designated Key Interfaces: Selection of the popular and open standards for the designated key interfaces is also a potential challenge for the designers. The selection should be based on the cost, required technical specification and availability of “open” products in the market and their usage by space industry. SubSection 3.3 above provides a list of some existing open and popular standards. Subsection 4.4 will discuss how to resolve this challenge by developing a business case to justify the selection of key interfaces and associated open standards.
Challenge 4: Management of Key Open Interfaces: Not all identified key interfaces in Challenge 2 can be designated an open interface standard at the initial system design phase due to market unavailability. Hence, managing these interfaces can be a potential challenge ensuring that they will be “open” by the time of Full Operational Capability (FOC) deployment. Section 4.3 discusses DOD guidance for managing key interfaces for military satellite system development.
U.S. DOD recommends OSA design using MOSA principles for future military satellite system development with a goal to achieve a balance between business and technical objectives that make a business sense in terms of (i) increase competition and lower system acquisition cost, and (ii) lower sustainment cost over its life cycle. MOSA design approach requires to implement five MOSA principles, including two Business (B) and three Technical (T) principles [1, 2]. Figure 8 captures these five B and T principles. Recently, U.S. Navy augmented MOSA principles with addition five Naval Open Architecture (NOA) principles, including two business and three technical principles as shown in Figure 8 [3].
MOSA and U.S. NOA approach.
Subsections 2.1 and 2.2 provide current implementation of the Technical principle 1 (T1) for the modular design of satellite Bus and mission PL, respectively. The remaining Subsections 4.3 and 4.4 discuss the implementation of T2, T6, Business principle 3 (B3), and B4 using DOD guidance for addressing the challenges presented in Subsection 4.1.
MOSA mandated the space system technical requirements be based on the maximum extent practicable on open standards as indicated in Section 3.2 of the U.S. DOD Guidebook for Program Managers [1]. The book provides MOSA2 guidelines and contract language for generating a Request for Proposal (RFP) [1]. At the minimum, the RFP shall incorporate the following MOSA tasks that can help to minimize the MOSA implementation risk in the design, build and test of new satellite systems:
Design the open system architecture using open interfaces. Implement the open interfaces using open standards for connecting HW-to-HW, and SW-to-SW.
The satellite system design shall accommodate growth and provide open interface standards to allow future reconfiguration and addition of new capabilities without large-scale redesign of the system.
Develop a capability roadmap for the system covering the life of the system following the completion of the rapid prototyping contract phase.
Address “Commercial Off the Shelf/Non-Developmental Item and Open System Software Licenses,” including Open Source Software, Verification of Open Architecture, Modular Open Systems Approach Metrics to be Reported, Modular Open System Approach Analysis Report.
Generate Open System Management Plan (OSMP) to capture all MOSA activities, technology roadmaps; Define and track MOSA metrics; Update roadmap. Following is a list of MOSA metrics that should be used to demonstrate an open satellite system:
Number and location of private extensions on open interfaces;
Contractor use of company private extensions on open standard middleware;
Open Software Design Tool Kits/Component Design Tool Kits (OSDTK/CDTK) will be provided with a minimum of Government Purpose Right (GPR); Minimal license fees may apply for COTS items;
Percentage of Chief Engineers, IPT Leads and program team members on architecture, software, logistics and Test & Evaluation trained in Open Systems Architecture and the MOSA tools;
Future Competition Strategy included in the OA Business plan within the OSMP;
MOSA (or OSA) requirements flowed down to sub-tier suppliers and recorded in IBM Rational® DOORS® requirements database or an MBSE digital model.
Design a system that consists of hierarchical collections of software, hardware, and firmware Configuration Items (CI’s). Document in the MOSA Analysis Report its modularization choices for the system design and any tradeoffs performed in accordance with the OA verification plan.
Document any processes or applications necessary to support MOSA in the MOSA Analysis Report.
The above U.S. DOD’s guidance encourages the satellite system designers to consider the above MOSA items in the design and build of the modular and open satellite Bus and mission payload for future space systems. The following section presents a proposal for assisting the satellite system designers to implement these MOSA items along with assessment tools provided by U.S. DOD.
It is observed that the U.S. DOD, U.S. civilian agencies (e.g., NASA, NOAA, etc) and U.S. satellite manufacturers/suppliers (e.g., LM, Boeing, Northrop Grumman (NG), Raytheon, L3, etc) are investigating approaches for the modular and open design and build of satellite Busses and mission PL’s using MOSA modular and open design principles. Figure 9 proposes an approach to design and build of future modular and open satellite Busses and mission PLs, and allowing the satellite buyers to: (i) Buy the satellite Bus (see Path A of the figure) and mission PL (see Path B) from different satellite manufacturers/suppliers, (ii) Have an option to choose a third satellite vendor to integrate the satellite Bus and mission PL (see Path C).
Proposed implementation approach for design and build of satellite Systems allowing buyers to acquire satellite bus and Mission PL independently.
The proposed MOSA implementation approach shown in Figure 4 consists of six basic steps that are incorporated into three execution paths, namely, Path A, Path B and Path C:
Path A is for the satellite Bus manufacturer/supplier. This path has three basic steps:
Step I-A: Develop Modular satellite Bus Architecture (MoBA). The MoBA subsystem components are described in Sections 1 and 2 (see Figure 3).
Step II-A: Designate KOSS’s and select open standards for all internal satellite Bus subsystem components. Open interface standards selection and designation of KOSS are discussed in Sections 3 and 4.
Step III-A: Design and build Open Modular satellite Bus System (OMoBS). This step is achieved by identifying all potential KOSS’s from the satellite Bus to any mission PL’s, i.e., the selected KOSS’s should be independent of mission types. The satellite Bus manufacturer is responsible for integrating all Bus components and have the satellite Bus ready for sale.
Path B is for the mission PL manufacturer/supplier. This path also has three basic steps that are similar to Path A:
Step I-B: Develop Modular Mission PL Architecture (MoPA). The MoPA subsystem components are also described in Sections 1 and 2 (see Figure 4).
Step II-B: Designate KOSS’s and select open standards for all internal Mission PL subsystem components. Open interface standards selection and designation of KOSS for mission PL are also discussed in Sections 3 and 4.
Step III-B: Design and build Open Modular Mission PL System (OMoPS). This step is achieved by identifying all potential KOSS’s from the any mission PL’s to satellite Bus, i.e., the selected KOSS’s should be independent of mission types. The mission PL manufacturer is responsible for integrating all mission PL components and have the PL ready for sale.
Path C is for the satellite system integrator. This path has additional three new steps:
Step IV: The system integrator works with satellite Bus and mission PL manufacturers to develop a satellite system interface specification specifying all “open” and “close” interfaces between the mission PL-and-satellite Bus. All open interfaces between the mission PL-and-satellite Bus shall be selected to meet the business and performance objectives approved by the buyer. The system integrator performs satellite Bus and mission PL integration using the approved interface specification.
Step V: System integrator performs system test and verification subject to buyer’s approval.
Step VI: System integrator delivers the satellite system to the buyer.
DOD has also developed MOSA tools to assist MOSA implementation and assessment of military satellite Bus and mission PL “Openness”. These tools can also be used for civilian and commercial applications. The DOD tools include MOSA Program Assessment and Rating Tool (PART), Open Architecture Assessment Tool (OAAT), and Key Open SubSystem (KOSS) Tool:
MOSA PART3: It is being used by DOD as the standard MOSA program assessment and rating tool for DOD space system programs.
MOSA OAAT4: Assist U.S. Navy program managers in assessing the “openness” of their programs. It aligns to the Open Architecture Assessment Model (OAAM) as approved by Assistant Secretary of The Navy (ASN) for Research, Development and Acquisition (RDA), which serves as the Navy Acquisition Executive. Other DOD agencies have also been using OAAT since the tool can provide a reproducible and objective method of conducting program assessments.
MOSA KOSS Tool5: One of the key MOSA principles is the Business Principle number 4, namely, Designate Key Interfaces (see Figure 8, B4). The identification of KOSS’s is an important task in realizing open systems. This MOSA principle requires the system designers to compromise between cost and performance by selecting a set of KOSS’s with their associated interfaces that can be assigned widely used open standards allowing for easy and affordable update and frequent refresh. MOSA KOSS tool provides guidance for KOSS’s identification and selection. The tool makes use of system capability road map, system requirements and Subject Matter Expert (SME), program’s sponsor and warfighter knowledge to identify the system/subsystem components expected to have a high volatility over the system life cycle. The tool specifies the key interfaces as those either side of volatile components. The tool will help the satellite system designer to identify and rank KOSS’s components that will meet both programmatic and technical requirements.
This section demonstrates how to use Steps II-A and II-B of the proposed MOSA implementation approach presented in Section 4.4 for the design and build of future resilient and robust satellite systems. Subsections 5.1 and 5.2 present potential modular-and-open satellite Bus and mission PL architectures, respectively.
To demonstrate how to transition the notional modular satellite Bus system architecture presented in Figure 3 to a modular-and-open satellite Bus architecture, this subsection provides an example for the transition of three modular Bus subsystems, namely, BC&DH (Bus Subsystem 3), BTT&C (Bus Subsystem 4) and BEPS (Bus Subsystem 5). These modular Bus subsystems are decomposed to subsystem component-level and analyzed for consideration as potential KOSS’s for open interface standardization. Table 1 summarizes the decomposition and analysis results for these three satellite Bus subsystems.
Modular satellite Bus subsystem component | Modular satellite Bus subsystem and component description | Recommendation for open interface Standardization (potential KOSS) |
---|---|---|
BC&DHS Component No. | Bus Command & Data Handing Subsystem (C&DHS) | |
BC&DHS-1 | Command Authentication Processing Unit (Sync Word Frame Lock, Unparsed Command) | Recommend for Interface standardization |
BC&DHS-2 | System Timing Unit | |
BC&DHS-3 | Fault Management Processing Unit (Execute Stored CMD Sequence, Monitor System Health) | Not recommended for interface standardization due to many variations between systems |
BC&DHS-4 | Bus Resource Management Processing Unit (Managing Internal and External Bus Data) | Recommend for open interface standardization |
BC&DHS-5 | Memory Storage Unit | |
BC&DHS-6 | Spacecraft Control Processor | |
BC&DHS-7 | Bus Telemetry Conditioning Processor | Not required; software driven functions. Should be considered in software interface analysis. |
BC&DHS-8 | Bus Cyber Security Unit | Recommend for open interface standardization |
BTT&CS Component No. | Bus Tracking-Telemetry & Command Subsystem (TT&CS) | |
BTT&CS-1 | TT&C Waveforms/MODEM | Recommend for open interface standardization |
BTT&CS-2 | TT&C Antenna Assembly for S-Band/L-Band | Not recommended for interface standardization. |
BTT&CS-3 | TT&C RF Front-End and Back-End Assembly | Recommend for open interface standardization |
BTT&CS-4 | Unified S-Band (USB) RX/TX Assembly | |
BTT&CS-5 | SGLS S-Band RX/TX Assembly | |
BTT&CS-6 | SGLS Base Band Signal Processing (USB Mode1, 2) | Recommend for open interface standardization |
BTT&CS-7 | In Band TT&C Processor Located at Private Station | Not recommended for interface standardization due to many variations between systems |
BTT&CS-8 | Power Controller Assembly | Recommend for open interface standardization |
BEPS Component No. | Bus Electrical Power Subsystem (EPS) | |
BEPS-1 | Solar Array (SA) | Recommend for open Interface standardization. |
BEPS-2 | Battery Assembly (BA) | Not recommended for interface standardization; Battery size will vary depending on the mission profile. Additional batteries could potentially require customized interfaces to tie all batteries to power bus. |
BEPS-3 | Solar Array Drive Assembly (SADA) | Recommend for open Interface standardization. |
BEPS-4 | Transient Filter Unit (TFU) | Not recommended for interface standardization |
BEPS-5 | Bus Power Regulation Unit (BPRU) | Recommend for open Interface standardization. . |
BEPS-6 | Fuse Box Assembly (FBA) | |
BEPS-7 | Pyro Relay Assembly (PRA) |
Satellite bus subsystems decomposition and potential KOSS.
In practice, the preliminary KOSS analysis results shown in Table 1 should be finalized by the system designer using DOD KOSS tool discussed in Section 4.4. As shown in Table 1, standardizing the BC&DH data interfaces will probably provide the biggest return on investment since the BC&DH subsystem interfaces with each onboard system. Incorporation of the timing interface along with the data interface will minimize the amount of connections, thus reducing overall system mass. Any interfaces that require a significant amount of analysis or Non-Recurring Engineering (NRE) hours is not a good candidate for standardization. The fault management processing interface is in this category, and it is not recommended for standardization.
This subsection provides an example for the transition of the notional modular mission PL architecture presented in Figure 4 to a modular-and-open mission PL architecture. Table 2 summarizes the decomposition and KOSS analysis results for four mission PL subsystems, including PAS (PL Subsystem 1), CPCom-RFS (PL Subsystem 2), PDPS (PL Subsystem 3) and PFTS (PL Subsystem 11).
Modular mission PL subsystem component | Modular mission PL subsystem and component description | Recommendation for open interface standardization (potential KOSS) |
---|---|---|
PAS Component No. | PL Antenna Subsystem (PAS) | |
PAS-1 | PL RF Antenna Configuration (PRAC) | Not recommended for interface standardization due to many variations between systems |
PAS-2 | Beam Forming Unit (BU) | |
PAS-3 | Antenna Controller (AC) | Recommend for Open Interface standardization |
PCom-RFS Component No. | PL Com RF Front-End/Back-End Subsystem (CPCom-RFS) | |
PCom-RFS-1 | PL LNA Component | Not recommended for interface standardization due to many variations between systems/subsystems |
PCom-RFS-2 | PL HPA Component | |
PCom-RFS-3 | Multi-RF Wideband Receiver (RX) | |
PcCm-RFS-4 | PL Up/Down Converters | Recommend for Open Interface standardization |
PCom-RFS-5 | Tunable IF Down Converters | |
PDPS Component No. | PL Digital Processing Subsystem (PDPS) | |
PDPS-1 | PL ADC/DAC | Not recommended for interface standardization due to many variations between systems |
PDPS-2 | FPGA Processor | |
PDPS-3 | PL MOD and DEMO (Optional) | |
PDPS-4 | Digital Network Switch (Optional) | |
PDPS-5 | PL System Controller | |
PTFS Component No. | P/L Frequency and Timing Subsystem (PFTS) | |
PFTS-1 | Atomic Clock Unit (ACU) | Not recommended for interface standardization; ACU and CM&CU will vary depending on mission type and mission requirements |
PFTS-2 | Clock Monitoring & Control Unit (CM&CU) | |
PFTS-3 | Frequency Generation & Up conversion Unit | Recommended for Interface standardization. |
PFTS-4 | Timing Variation and Frequency Stability | Not recommended for interface standardization |
Mission payload subsystems decomposition and potential KOSS.
The mission PL digital processing system is not recommended for interface standardization due to many variations between systems and subsystems. Multi-RF Wideband RX Up/Down Converters and Tunable IF Down Converters require a significant amount of analysis or NRE hours and are also not a good candidate for standardization. Again, DOD KOSS tool should be used to finalize the KOSS analysis results presented here for actual design and build of the satellite systems.
The chapter provides an overview of existing modular satellite Bus and mission PL architectures and associated standards for communication data Busses. The chapter defines open and close interfaces along with industry approved popular standards and discusses the interface design challenges. Moreover, the chapter provides an overview of MOSA and related DOD guidance and assessment tools to address the interface design challenges. Examples for the design and build of modular-and-open satellite Bus and mission PL architectures are also presented. The intent of this chapter is to provide an innovative approach for the satellite system designer to design and build of the next generation satellite achieving a balance between business and technical objectives that make a business sense for both the satellite manufacturers and buyers in terms of lower system acquisition and sustainment costs over its life cycle. The MOSA implementation approach presented here allows the satellite manufacturers to build the satellite Bus and mission PL separately for more production, flexibility, and market competition. Concurrently, the approach also allows the satellite buyers to buy satellite Bus at high volume with reduced unit costs and less schedule risk. Another benefit for the satellite buyer is the adaptability of changing the requirements on the mission PL without impacting the satellite Bus.
Although the preparation of this work was not funded by The Aerospace Corporation, but the author acknowledges the work presented in this chapter was based on his knowledges accumulated over the years from many space programs at The Aerospace Corporation, Raytheon and Jet Propulsion Laboratory. In addition, the author would like to express his appreciation to Aerospace’s manager, Ms. Navneet Mezcciani, for her professional support.
The preparation of this chapter was not funded by the Aerospace Corporation, and it was done by the authors using his own time and resources, thus it does not represent the Aerospace Corporation’s view on the DOD guidance for MOSA implementation and the proposed system architecture solutions.
The author wishes to thank his wife, Thu-Hang Nguyen, for her enormous patience and boundless support during the preparation of this chapter.
An anastomosis is a surgical connection between two structures. It usually means a connection that is created between tubular structures, such as blood vessels or loops of the intestine. Surgeons can choose to join together the two parts of the intestine by using either sewing (sutures) or staples. Sewing by hand has been used successfully for over 100 years. However, stapling takes less time to perform. As with any intervention, anastomosis carries some risks. These include blood clots, bleeding, scarring, blockage, stricture, or abnormal narrowing, damage to the surrounding structures, and infections, all of which can lead to anastomotic leakage, sepsis, septic shock, or even death (Figures 1 and 2).
Intraoperative aspect of an anastomosis performed manually at the level of the small bowel.
Intraoperative aspect of an anastomosis performed mechanically at the level of the small bowel.
Barbed sutures are available in a variety of both absorbable and nonabsorbable monofilament materials. Specifically, currently available bidirectional and unidirectional barbed suture materials include PDO, polyglyconate, poliglecaprone 25, glycomer 631, nylon, and polypropylene. A study performed by Wiggins [1] searched through a systematic review and meta-analysis for the benefits of barbed suture utilization in gastrointestinal anastomosis. The conclusion was that the use of barbed sutures for gastrointestinal anastomosis appears to be associated with shorter overall operative times. There was no difference in rates of complications (including anastomotic leak, bleeding, or stricture) compared with standard suture materials.
The study included consecutive CD patients with ileal/ileocolonic strictures who had SWE shear wave elastography within one week of surgical resection.
The SWE of the stenotic bowel wall was compared to the biofragmentable anastomosis ring used for gastrointestinal anastomoses in a literature review conducted by Bobkiewicz and coauthors [2].
The theoretical idea was that a biofragmentable anastomosis ring (BAR) could be used instead of manual and stapled anastomoses in the upper and lower GI tracts.
The aim of this study was to see how effective BAR was for bowel anastomoses using our own content. Methodologies: Between 2004 and 2014, a retrospective study was conducted on a total of 203 patients who underwent bowel surgery with BAR anastomosis in the upper and lower gastrointestinal tract. The study concluded that using BAR for GI tract anastomoses is an easy and quick procedure with a low rate of perioperative mortality (0.5%) and complication rates (Figures 3 and 4).
Foreign body reaction at the level of the tissues containing suture material.
Colorful surgical nylon monofilament suture with a curved needle.
The ideal stapling device should be capable of rapid creation of an anastomosis with serosal apposition without the persistence of a foreign body or a foreign body reaction, which potentially contributes to early anastomotic dehiscence or late anastomotic stricture (Figures 5 and 6).
Linear surgical stapler.
(a and b) circular stapling device and its mode of appliance.
While 2-row stapling has become normal in low anterior resections (LARs), it has no effect on morbidity or the incidence of AL.
Conducted by Nekliudov [3] is the first prospective, randomized clinical trial that compares the success rate of modern 3-row circular staplers to that of traditional 2-row staplers.
According to the hypothesis, the frequency of AL in the 3-row stapler group is not significantly higher than in the 2-row stapler group.
The rate of AL, as determined by imaging studies and measured using the Pearson chi-squared test and Fisher exact test, is the primary endpoint.
Secondary outcomes include AL severity (A, B, or C), anastomotic bleeding, postoperative complication rate (graded using the Clavien-Dindo classification), reintervention rate, stapler dysfunction rate, complications of nonfunctioning stoma, overall and cancer-specific quality of life (measured using short-form (36) questionnaire and quality-of-life (30) questionnaire core, respectively), fecal incontinence, and overall and cancer-specific quality of life.
Following the LAR, both patients will be tracked for a period of 12 months.
This is the first prospective randomized trial to look at the efficacy of 3-row staplers for colorectal anastomosis following rectal cancer surgery.
It could show that 3-row circular staplers are feasible in LAR in terms of short- and long-term patient outcomes (Figures 7 and 8).
2-row staple lines.
3-row staple lines.
A study performed by Jeong and coauthors [4] was assembled to report an institution’s experiences with transanal total mesorectal excision (TME) of rectal cancer using single-port equipment and to discuss the feasibility and safety of the technique. In the institution mentioned, 10 patients (6:4) treated with transanal TME with colorectal anastomosis were examined (Figure 9).
Complete TME specimen (a) and sectioned (b) after abdomino-perineal resection with intact mesorectum.
In six of 10 patients, TME was done without the use of a laparoscope.
The average time spent on the operating table was 303.5 minutes.
The distal margin was 2.1 (0.2–4.2) cm on average.
The average number of lymph nodes harvested is 17.5.
Except for one patient who had an anastomotic leak, the majority of patients began dietary intake on POD 3 and were discharged on POD 7.
The only postoperative complication was an anastomotic leak.
Conclusions: In selected cases of rectal cancer, pure natural orifice transluminal endoscopic surgery (NOTES) TME with coloanal anastomosis was found to be healthy and feasible.
Anastomotic leak (AL) is a common problem in colorectal surgery, and its prevalence has remained steady in recent years.
The use of an intra-abdominal drain or mechanical bowel preparation to prevent AL has been shown to be ineffective and should be avoided.
The function of oral antibiotic preparation regimens should be explained and compared to other routes of administration, such as intravenous or enema, according to a study conducted by Meyer and coauthors [5].
Parallel to this, preoperative antibiotherapy should target pathogens that induce collagenase, as defined by the microbiome study.
Fluorescence angiography may minimize AL even further, resulting in major intraoperative improvements in surgical strategies.
Fluorescence angiography can be used more often.
There have been studies, such as the one by Gained and coauthors [6], that looked at the literature’s connection between colorectal cancer recurrence, microbiome, and anastomotic leakage, and among the findings, one can find the aspect according to which the numerous mechanisms by which environmental factors act on the microbiome to alter its composition and function, with the net effect of adversely affecting oncological outcomes following surgery, are well documented and increasing.
Diet, antibiotic use, the procedures used to prepare the colon for surgery, and the physiological discomfort of the procedure are all examples of environmental causes.
Furthermore, using next-generation sequencing technologies to investigate the intestinal microbiome has the ability to affect cancer outcomes following colon resection. In a systematic review that targeted the endoscopic management of early postoperative complications, a literature search was performed by Clifford and coauthors [7] for published full text articles using the PubMed, Cochrane, and Scopus databases using the search criteria string “colorectal anastomotic (“leak” or “bleed”),” “endoscopy,” and “endoscopic management.” Endoscopic therapy in the management of stable patients with colorectal anastomotic leaks appears safe and is associated with the high rates of technical performance in selected patients, according to a review of 89 papers.
The most suitable method, patient selection, and considering the practical and long-term consequences of this approach remain challenging.
To fully assess the function of these novel strategies, further data from large prospective cohort studies are needed.
Shalaby and coauthors [8] conducted another systematic review on endoluminal vacuum-assisted therapy as a salvage treatment for rectal anastomotic leakage and found the following findings among 476 articles identified, 17 studies reporting on 276 patients:
The weighted mean success rate was 853% (95% confidence interval [CI]: 801–905), with a median time from the start of EVT to full healing of 47 (range 40–105) days.
The weighted mean rate of stoma reversal was 759% (646–872%) across the studies.
After EVT, twenty-five patients (91%) needed additional interventions.
Thirty-eight patients (138%) experienced complications as a result of the procedure.
The weighted mean complication rate was 111% (60–162%) across all tests.
Preoperative radiotherapy, the absence of a diverting stoma, complications, and male sex were all found to be significantly associated with failure.
According to the findings of the study, EVT is linked to a high rate of full healing of anastomotic leakage and stoma reversal.
In appropriately selected patients with anastomotic leakage, it is a viable choice.
Colorectal cancer surgery is thought to involve “high tie” and “low tie” of the inferior mesenteric artery (IMA).
However, the blood supply of the anastomosis is closely linked to the ligation stage, which can increase the leakage rate, and it is unclear which technique confers a lower anastomotic leakage rate (AL) and survival advantage.
The aim of the literature review, as stated by Yang and coauthors [9], was to compare the efficacy and impact of IMA high ligation versus IMA low ligation on anastomotic leakage, lymph node yield rates, and 5-year survival.
Finally, after reviewing studies from 1990 to 2017, researchers came to the conclusion that neither the high-tie nor the low-tie approach has any data in terms of anastomotic leakage, harvested lymph nodes, or 5-year survival rates.
More RCT is needed.
A study conducted by Simianu and coauthors [10] looked at the recency effect, which means that people place disproportionate emphasis on events that occurred recently when making decisions, but the magnitude of this influence on surgeons’ decisions is uncertain.
The use of preventative leak testing before and after colorectal operations with anastomotic leaks is examined in this study to see whether there is a recency effect in surgeons.
A prospective cohort of adult patients (aged 18 years) undergoing elective colorectal surgery at Washington State hospitals participating in the Surgical Care and Outcomes Assessment Program was used to develop the materials and methods (2006–2013).
The key outcome measure was the difference in leak monitoring between 6 months before and 6 months after an anastomotic leak.
A leak rate of 2.6% (n = 124) was found in 4854 elective colorectal operations performed by 282 surgeons at 44 hospitals.
The anastomosis was not checked in 40 leaks (32%), which were spread through 25 surgeons.
While the small sample size restricted the ability to detect an overall difference in leak testing use, 9 (36%) of the 25 surgeons increased their leak testing by 5% or more after leaks in cases where the anastomosis was not checked.
The above facts led to the conclusion that only one-third of qualified surgeons demonstrated the recency effect.
Understanding the degree to which the recency effect influences clinical decisions may be useful in developing quality management strategies that involve clinician’s behavior change.
Wang and colleagues [11] contrasted many aspects of robot-assisted versus laparoscopic surgery for rectal cancer by reviewing 20 studies with a total of 5496 patients, divided into a robot-assisted surgery group (
Longer operating period (OR: 0.48, 95% CI: 0.14, 0.82), lower conversion to open surgery rate (OR: 0.55, 95% CI: 0.44, 0.69), shorter LOS (Length Of Stay) (OR: −0.15, 95% CI: −0.30, 0.00), faster bowel function recovery (OR: −0.38, 95% CI: −0.74, −0.02), and lower postoperative complications were all correlated with the robot-assisted surgery community (OR: 0.79, 95% CI: 0.65, 0.97).
There were no substantial differences between groups in EBL, anastomosis leak rate, or oncological outcomes such as the number of lymph nodes removed, the DRM, or the PCRM (Figures 10 and 11).
Dehiscence at the level of the anastomosis.
Methylene blue test.
Postoperative ileus generates a high impact on morbidity, hospital stay, and costs. Vergara Fernandez and coauthors [12] conducted a randomized controlled trial of 64 patients who had elective colorectal surgery with primary anastomosis in a tertiary referral center. Patients were divided into two groups: (i) those who chewed their gums (
Illustration of a simple abdominal X-ray exam in a patient with bowel obstruction.
It can sometimes be treated endoscopically, when surgery is contraindicated, by performing, as was found in a case report by Deng and team [13] with minimally invasive endoscopic approach was adopted to repair the obstruction. A needle knife was used to puncture the linear white scar, and contrast agent was injected under endoscopy and fluoroscopic guidance. Fluoroscopically, the proximal bowel was identified and a dual knife-mediated membrane puncture was performed. A guidewire was then passed through the incision into the proximal bowel and progressive pneumatic dilatation was performed successively with a controlled radial expansion balloon dilator until a 1.8-cm-diameter dilation was achieved. After conventional balloon dilatation, the endoscope easily passed through the anastomosis without any patient discomfort. There were no postoperative signs of immediate or delayed complications (Figure 13).
Colonoscopic aspect of a anastomotic stenosis.
Following TME, postoperative defecation dysfunctions known as “anterior resection syndrome” might appear.
Straight colorectal anastomosis (SCA), colon J-pouch (CJP), and side-to-end anastomosis are all common reconstruction techniques (SEA) (Figures 14 and 15).
Types of anastomoses illustrated.
Aspect of the J-pouch.
There are no prospective, randomized, multi-center trials that compare their functional results, including long-term evaluations.
As a result, the primary endpoint of a study designed by Marti and collab [14] that included 336 patients from 15 hospitals who were randomized had a comparison of composite evacuation scores 12 months after TME as a primary endpoint.
Secondary endpoints included a comparison of composite evacuation and incontinence ratings at 6, 18, and 24 months after surgery, as well as morbidity and overall survival.
The study looked at the “per protocol” (PP) population, which complied with all-trial criteria, as well as the “intention-to-treat” (ITT) population.
At any time point, there were no statistically significant variations in the composite evacuation ratings of the PP and ITT populations.
Similarly, at any time point, there was no statistically significant difference in composite incontinence scores for the PP and ITT populations among the three trial weapons.
Conclusions: Within the scope of the investigation, surgeons in charge can continue to conduct intestinal continuity reconstruction following TME at their discretion.
In addition to the studies previously reported, Hou and collab [15] investigated whether the use of side-to-end anastomosis (SEA) in sphincter-preserving resection (SPR) is problematic and conducted a meta-analysis to compare the safety and efficacy of SEA with colonic J-pouch (CJP) anastomosis, which has been shown to improve postoperative bowel function.
The meta-analysis included a total of 864 patients from 10 RCTs.
At 12 months after SPR, patients who underwent SEA had a higher defecation frequency and a lower incidence of incomplete defecation than those who underwent CJP anastomosis with low heterogeneity and a lower incidence of incomplete defecation at 3 months after surgery.
The SEA group also had a shorter operating period with no substantial heterogeneity.
The SEA group had a higher anorectal resting strain, but there was a lot of heterogeneity.
There were no significant differences between the groups in terms of efficacy outcomes such as defecation frequency, urgency, incomplete defecation, use of pads, enema, medications, anorectal squeeze pressure, and maximum rectal volume, or safety outcomes such as operating time, blood loss, use of protective stoma, postoperative complications, clinical outcomes, and complication rates.
In comparison with CJP anastomosis, the current evidence indicates that SEA is a successful anastomotic technique for achieving comparable postoperative bowel function without raising the risk of complications.
Shorter operating times, a lower occurrence of incomplete defecation three months after surgery, and improved sphincter function are all advantages of SEA.
However, after SPR, long-term defecation frequency should be closely monitored.
Assessing intraoperative perfusion with indocyanine green (ICG) and near-infrared (NIR) visualization can aid in selecting the degree of intestinal transection and subsequent anastomotic vascular sufficiency, according to the theory.
In a prospective study of nonselected patients undergoing any elective colorectal surgery with anastomosis in three tertiary hospitals over a 3-year span, NIR-ICG was used to look at anastomosis perfusion.
In addition to standard operator visual evaluation alone, a standard procedure was followed to evaluate NIR-ICG perfusion before and after anastomosis construction.
The researchers looked at 540 patients (median age 64 years, 279 men) who had surgery for neoplastic (330) and benign (174) pathology.
A total of 425 operations (853%) were initiated laparoscopically, with a 59% conversion rate.
In total, 220 patients (437%) had high anterior resection or reversal of Hartmann’s procedure, and 90 patients (179%) had low anterior resection.
ICG angiography was effective in every patient, with leak rates of 24% (12 of 504) overall, 26% for colorectal anastomoses, and 3% for low anterior resection.
The anastomotic leak rates were lower when NIR-ICG imaging was used than in the participating centers from over 1000 related operations conducted with the same technique but without NIR-ICG technology. As a result, the study’s findings were as follows:
Patients undergoing elective colorectal surgery should have their NIR-ICG levels checked on a regular basis.
The use of NIR-ICG can alter intraoperative decisions, potentially lowering anastomotic leak rates.
Kryzauskas conducted a systematic review and meta-analysis of publications, which included a total of 23 studies, with a total of 7115 patients, that were conducted to see whether intraoperative testing of the mechanical integrity and perfusion of the colorectal anastomosis could minimize the risk of AL. Intraoperative checks for the integrity (OR: 0.52, 95% CI: 0.34–0.82, P.001) and perfusion (OR: 0.40, 95% CI: 0.22–0.752, P.001) of the lower gastrointestinal tract anastomoses are linked to a substantially lower AL rate, according to a pooled study. The researchers came to the conclusion that intraoperative monitoring for anastomosis integrity or perfusion both reduced the AL dose. Studies combining these two anastomosis testing methods, especially intraoperative endoscopy and indocyanine green fluorescence angiography, could be very promising for further AL reduction. Since diabetes is a well-established independent factor that results in higher anastomotic leakage rates, the effects of biological sealants on colorectal anastomosis and their potential impact in patients with severe diabetes were studied in depth.
Fibrin sealants have been used to avoid anastomotic dehiscence in both laboratory and clinical trials.
We looked for existing evidence in the field by searching Medline (1966–2016) and Scopus (2004–2016). There is no evidence to support the use of fibrin sealants as a supplement in diabetic patients undergoing colorectal surgery at this time.
Experimental animal models with severe diabetes may be very useful in this area, and more research is required before fibrin sealants are used in a clinical environment.
In a systematic study and meta-analysis, Wu and team [16] analyzed the air leak test conducted intraoperatively.
The intraoperative air leak test (ALT) is a standard intraoperative test used to detect anastomosis that is mechanically inadequate.
The aim of this meta-analysis is to see whether ALT can help reduce postoperative colorectal anastomotic leakage (CAL).
The report included 22 experiments, with the following being the most notable.
According to the data, conducting an ALT using the recorded technique does not substantially reduce the clinical CAL rate, but it is still important due to the increased risk of CAL in ALT(+) cases.
Additional repairs, unfortunately, may not be successful in reducing this risk using current methods.
The findings of this study call for the standardization of ALT methodology and the creation of successful methods for repairing ALT(+) anastomoses.
A meta-analysis of randomized controlled trials on the use of suction drains following rectal surgery was conducted by Guerra and coauthors [17], and after looking at 760 patients from four RCTs that were eligible (RCT comparing drained with undrained anastomoses following rectal surgery), the use of drains showed little benefit in terms of anastomotic leak, pelvic complications, or reintervention.
On the other hand, the drained party had a slightly higher rate of postoperative bowel obstruction.
The researchers concluded that using pelvic drains routinely does not provide a major benefit in preventing postoperative complications following rectal surgery with extraperitoneal anastomosis.
Furthermore, a higher risk of bowel obstruction following surgery should be considered.
Non-surgery-based intraoperative risk factors for anastomotic healing also influence surgical outcome.
After analyzing 117 papers, a review by van Rooijen and team [18] provided an overview of potential modifiable risk factors that could play a role during the operation, and the results (the main outcome measure was the risk of anastomotic leakage and other postoperative complications during colorectal surgery) revealed that diabetes mellitus, hyperglycemia and a high HbA1c, anemia, and data on blood pressure, inotropes/vasopressors, oxygen supplementation, form of analgesia, and goal-directed fluid therapy are all unequivocal.
There was no research that looked into the effect of body core temperature or mean arterial pressure on CAL.
Subjective considerations including the surgeon’s own evaluation of local perfusion and the visibility of the operating field have not been studied for incidence in CAL patients.
The findings revealed that in order to enhance colorectal treatment, both surgery-related and non-surgery-related risk factors that can be changed must be established.
In their ongoing attempt to minimize the number of CAL, surgeons and anesthesiologists can collaborate on these issues.
In the Netherlands, a multicenter cohort study is currently being conducted to determine individual intraoperative risk factors for CAL.
In perforated diverticulitis, for example, there has been no consensus in the management, which is why the Shaban and coauthors [19] felt compelled to perform a systematic review and meta-analysis, particularly because many surgeons choose the Hartmann’s procedure to avoid the risk of an anastomotic leak.
As a result, we proposed that in certain patients, resection with primary anastomosis is a healthy option.
The study found 1933 abstracts, of which 14 trials (2 RCTs, 4 prospective non-randomized, and 8 retrospective non-randomized) with 765 patients met the inclusion criteria, with 482 in the Hartmann’s group and 283 in the primary anastomosis group.
Primary anastomosis had a slightly lower mortality rate (10.6%) than Hartmann’s (20.7%) (
The rate of morbidity was also lower (41.8 vs. 51.2%) (
Primary anastomosis had a risk ratio of 0.92 in favor of mortality (
The average rate of anastomotic leak was 5.9%.
Resection and primary anastomosis should be considered as a feasible and secure operative technique in selected patients with perforated diverticulitis, according to the findings of the study.
However, there is a scarcity of high-level data, and further research is needed.
Resection with primary anastomosis (PRA) with or without diverting ileostomy (DI), Hartmann’s procedure (HP), laparoscopic lavage (LL), and damage control surgery were among the aspects reviewed in another and more complicated approach to damage control strategy in perforated diverticulitis with generalized peritonitis performed by Sohn and team [20] (DCS).
DCS is divided into two levels.
Limited resection of the diseased colon, oral and aboral closure, lavage, and vacuum-assisted abdominal closure are all options for emergency surgery.
After proper resuscitation, a second look operation is performed: definitive reconstruction with colorectal anastomosis (±DI) or HP.
The inclusion criteria were fulfilled by eight observational studies involving 256 patients.
There was no randomized study available.
Purulent peritonitis affected 67% of the patients, while feculent peritonitis affected 30%. Hinchey stage II diverticulitis was observed in 3% of the patients. The Mannheim peritonitis index (MPI) was greater than 26 in 49% of the cases. In 73% of cases, a colorectal anastomosis was developed during the second surgery. DI was used in 15% of the above group. HP was given to the remaining 27%. The postoperative mortality rate was 9%, and the morbidity rate was 31%. The rate of anastomotic leak was 13%. Without a stoma, 55% of patients were discharged.
Conclusions: DCS is a safe treatment for acute perforated diverticulitis with generalized peritonitis, with a high incidence of colorectal anastomosis and stoma-free hospital discharge in more than half of patients.
Pickhardt [21] compared the accuracy of CT colonography versus optical colonoscopy for neoplastic involvement at the surgical anastomosis 1 year after curative-intent colorectal cancer resection for neoplastic involvement at the surgical anastomosis.
As part of a prospective, multicenter study, 201 patients (mean age 58.6 years; 117 men, 84 women) underwent same-day contrast-enhanced CT colonography and colonoscopy approximately 1 year (mean, 12.1 months; median, 11.9 months) after colorectal cancer resection.
Many of the patients enrolled had no clinical signs of illness and were found to have a low risk of recurrence (stage I–III).
Relevant intraluminal anastomotic pathology tends to be very rare 1 year after colorectal cancer resection in lower-risk cohorts, according to the findings.
Diagnostic contrast-enhanced CT colonography, unlike colonoscopy, successfully measures both the intraluminal and extraluminal dimensions of the anastomosis.
Yang and collab [22] investigated the use of stents as a bridge to surgery in the treatment of acute left-sided obstructive colorectal cancer.
In a meta-analysis of randomized controlled trials, the factor according to which the trials were conducted was taken into account.
The use of self-expanding metallic stents (SEMS) as a bridge to surgery in the treatment of acute left-sided obstructive colorectal cancer has remained contentious.
The following were the outcomes:
We chose 8 RCTs papers with a total of 497 instances.
The stent group had significantly lower directly stoma rates, significantly higher active primary anastomosis rates, and significantly lower post-procedural complication rates.
The stent party, on the other hand, had substantially higher tumor recurrence rates, leading to the following conclusions:
This meta-analysis confirms that SEMS placement can lower the rate of direct stomas and increase the rate of active primary anastomosis; however, it is linked to a higher rate of tumor recurrence.
Laparoscopic anterior resection (LAR) is nowadays routine practice in specialized high-volume centers, with equivalent oncological outcomes to open surgery. Anastomotic leakage (AL) remains one of the most threatening complications in colorectal surgery with the incidence of up to 20%. Therefore, recognition of the risk factors of postoperative complications is essential in order to be prevented. Moreover, one must underline the importance of some risk factors such as age, nutrition status of the patient, experience of the surgeon, and many other factors that influence outcome of colorectal surgery. Some risk factors can be modified before the intervention to prevent postoperative complications. Contrary to that, long-term postoperative complications may promote tumor recurrence and decrease survival.
The author declares no conflict of interest.
As an Open Access publisher, IntechOpen is dedicated to maintaining the highest ethical standards and principles in publishing. In addition, IntechOpen promotes the highest standards of integrity and ethical behavior in scientific research and peer-review. To maintain these principles IntechOpen has developed basic guidelines to facilitate the avoidance of Conflicts of Interest.
",metaTitle:"Conflicts of Interest Policy",metaDescription:"As an Open Access publisher, IntechOpen is dedicated to maintaining the highest ethical standards and principles in publishing. In addition, IntechOpen promotes the highest standards of integrity and ethical behavior in scientific research and peer-review.",metaKeywords:null,canonicalURL:"/page/conflicts-of-interest-policy",contentRaw:'[{"type":"htmlEditorComponent","content":"In each instance of a possible Conflict of Interest, IntechOpen aims to disclose the situation in as transparent a way as possible in order to allow readers to judge whether a particular potential Conflict of Interest has influenced the Work of any individual Author, Editor, or Reviewer. IntechOpen takes all possible Conflicts of Interest into account during the review process and ensures maximum transparency in implementing its policies.
\\n\\nA Conflict of Interest is a situation in which a person's professional judgment may be influenced by a range of factors, including financial gain, material interest, or some other personal or professional interest. For IntechOpen as a publisher, it is essential that all possible Conflicts of Interest are avoided. Each contributor, whether an Author, Editor, or Reviewer, who suspects they may have a Conflict of Interest, is obliged to declare that concern in order to make the publisher and the readership aware of any potential influence on the work being undertaken.
\\n\\nA Conflict of Interest can be identified at different phases of the publishing process.
\\n\\nIntechOpen requires:
\\n\\nCONFLICT OF INTEREST - AUTHOR
\\n\\nAll Authors are obliged to declare every existing or potential Conflict of Interest, including financial or personal factors, as well as any relationship which could influence their scientific work. Authors must declare Conflicts of Interest at the time of manuscript submission, although they may exceptionally do so at any point during manuscript review. For jointly prepared manuscripts, the corresponding Author is obliged to declare potential Conflicts of Interest of any other Authors who have contributed to the manuscript.
\\n\\nCONFLICT OF INTEREST – ACADEMIC EDITOR
\\n\\nEditors can also have Conflicts of Interest. Editors are expected to maintain the highest standards of conduct, which are outlined in our Best Practice Guidelines (templates for Best Practice Guidelines). Among other obligations, it is essential that Editors make transparent declarations of any possible Conflicts of Interest that they might have.
\\n\\nAvoidance Measures for Academic Editors of Conflicts of Interest:
\\n\\nFor manuscripts submitted by the Academic Editor (or a scientific advisor), an appropriate person will be appointed to handle and evaluate the manuscript. The appointed handling Editor's identity will not be disclosed to the Author in order to maintain impartiality and anonymity of the review.
\\n\\nIf a manuscript is submitted by an Author who is a member of an Academic Editor's family or is personally or professionally related to the Academic Editor in any way, either as a friend, colleague, student or mentor, the work will be handled by a different Academic Editor who is not in any way connected to the Author.
\\n\\nCONFLICT OF INTEREST - REVIEWER
\\n\\nAll Reviewers are required to declare possible Conflicts of Interest at the beginning of the evaluation process. If a Reviewer feels he or she might have any material, financial or any other conflict of interest with regards to the manuscript being reviewed, he or she is required to declare such concern and, if necessary, request exclusion from any further involvement in the evaluation process. A Reviewer's potential Conflicts of Interest are declared in the review report and presented to the Academic Editor, who then assesses whether or not the declared potential or actual Conflicts of Interest had, or could be perceived to have had, any significant impact on the review itself.
\\n\\nEXAMPLES OF CONFLICTS OF INTEREST:
\\n\\nFINANCIAL AND MATERIAL
\\n\\nNON-FINANCIAL
\\n\\nAuthors are required to declare all potentially relevant non-financial, financial and material Conflicts of Interest that may have had an influence on their scientific work.
\\n\\nAcademic Editors and Reviewers are required to declare any non-financial, financial and material Conflicts of Interest that could influence their fair and balanced evaluation of manuscripts. If such conflict exists with regards to a submitted manuscript, Academic Editors and Reviewers should exclude themselves from handling it.
\\n\\nAll Authors, Academic Editors, and Reviewers are required to declare all possible financial and material Conflicts of Interest in the last five years, although it is advisable to declare less recent Conflicts of Interest as well.
\\n\\nEXAMPLES:
\\n\\nAuthors should declare if they were or they still are Academic Editors of the publications in which they wish to publish their work.
\\n\\nAuthors should declare if they are board members of an organization that could benefit financially or materially from the publication of their work.
\\n\\nAcademic Editors should declare if they were coauthors or they have worked on the research project with the Author who has submitted a manuscript.
\\n\\nAcademic Editors should declare if the Author of a submitted manuscript is affiliated with the same department, faculty, institute, or company as they are.
\\n\\nPolicy last updated: 2016-06-09
\\n"}]'},components:[{type:"htmlEditorComponent",content:"In each instance of a possible Conflict of Interest, IntechOpen aims to disclose the situation in as transparent a way as possible in order to allow readers to judge whether a particular potential Conflict of Interest has influenced the Work of any individual Author, Editor, or Reviewer. IntechOpen takes all possible Conflicts of Interest into account during the review process and ensures maximum transparency in implementing its policies.
\n\nA Conflict of Interest is a situation in which a person's professional judgment may be influenced by a range of factors, including financial gain, material interest, or some other personal or professional interest. For IntechOpen as a publisher, it is essential that all possible Conflicts of Interest are avoided. Each contributor, whether an Author, Editor, or Reviewer, who suspects they may have a Conflict of Interest, is obliged to declare that concern in order to make the publisher and the readership aware of any potential influence on the work being undertaken.
\n\nA Conflict of Interest can be identified at different phases of the publishing process.
\n\nIntechOpen requires:
\n\nCONFLICT OF INTEREST - AUTHOR
\n\nAll Authors are obliged to declare every existing or potential Conflict of Interest, including financial or personal factors, as well as any relationship which could influence their scientific work. Authors must declare Conflicts of Interest at the time of manuscript submission, although they may exceptionally do so at any point during manuscript review. For jointly prepared manuscripts, the corresponding Author is obliged to declare potential Conflicts of Interest of any other Authors who have contributed to the manuscript.
\n\nCONFLICT OF INTEREST – ACADEMIC EDITOR
\n\nEditors can also have Conflicts of Interest. Editors are expected to maintain the highest standards of conduct, which are outlined in our Best Practice Guidelines (templates for Best Practice Guidelines). Among other obligations, it is essential that Editors make transparent declarations of any possible Conflicts of Interest that they might have.
\n\nAvoidance Measures for Academic Editors of Conflicts of Interest:
\n\nFor manuscripts submitted by the Academic Editor (or a scientific advisor), an appropriate person will be appointed to handle and evaluate the manuscript. The appointed handling Editor's identity will not be disclosed to the Author in order to maintain impartiality and anonymity of the review.
\n\nIf a manuscript is submitted by an Author who is a member of an Academic Editor's family or is personally or professionally related to the Academic Editor in any way, either as a friend, colleague, student or mentor, the work will be handled by a different Academic Editor who is not in any way connected to the Author.
\n\nCONFLICT OF INTEREST - REVIEWER
\n\nAll Reviewers are required to declare possible Conflicts of Interest at the beginning of the evaluation process. If a Reviewer feels he or she might have any material, financial or any other conflict of interest with regards to the manuscript being reviewed, he or she is required to declare such concern and, if necessary, request exclusion from any further involvement in the evaluation process. A Reviewer's potential Conflicts of Interest are declared in the review report and presented to the Academic Editor, who then assesses whether or not the declared potential or actual Conflicts of Interest had, or could be perceived to have had, any significant impact on the review itself.
\n\nEXAMPLES OF CONFLICTS OF INTEREST:
\n\nFINANCIAL AND MATERIAL
\n\nNON-FINANCIAL
\n\nAuthors are required to declare all potentially relevant non-financial, financial and material Conflicts of Interest that may have had an influence on their scientific work.
\n\nAcademic Editors and Reviewers are required to declare any non-financial, financial and material Conflicts of Interest that could influence their fair and balanced evaluation of manuscripts. If such conflict exists with regards to a submitted manuscript, Academic Editors and Reviewers should exclude themselves from handling it.
\n\nAll Authors, Academic Editors, and Reviewers are required to declare all possible financial and material Conflicts of Interest in the last five years, although it is advisable to declare less recent Conflicts of Interest as well.
\n\nEXAMPLES:
\n\nAuthors should declare if they were or they still are Academic Editors of the publications in which they wish to publish their work.
\n\nAuthors should declare if they are board members of an organization that could benefit financially or materially from the publication of their work.
\n\nAcademic Editors should declare if they were coauthors or they have worked on the research project with the Author who has submitted a manuscript.
\n\nAcademic Editors should declare if the Author of a submitted manuscript is affiliated with the same department, faculty, institute, or company as they are.
\n\nPolicy last updated: 2016-06-09
\n"}]},successStories:{items:[]},authorsAndEditors:{filterParams:{sort:"-totalCites"},profiles:[{id:"131328",title:"Prof.",name:"Abdennasser",middleName:null,surname:"Chebira",slug:"abdennasser-chebira",fullName:"Abdennasser Chebira",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131328/images/system/131328.jpg",biography:"Dr. Abdennasser Chebira received his Ph.D. degree in Electrical Engineering and Computer Sciences from PARIS XI University, Orsay, France, in 1994. Since September 1994 he works as Professor Assistant at Sénart Institute of Technology of PARIS XII – Val de Marne University. He is a staff researcher at Images, Signal and Intelligent Systems Laboratory (LISSI / EA 3956) of this University. His current research works concern selforganizing neural network based multi-modeling, hybrid neural based information processing systems; Neural based data fusion and complexity estimation.",institutionString:null,institution:null},{id:"262400",title:"Dr.",name:"Thiago Lopes",middleName:null,surname:"Rocha",slug:"thiago-lopes-rocha",fullName:"Thiago Lopes Rocha",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"327936",title:"Dr.",name:"Mohamed",middleName:null,surname:"Anli",slug:"mohamed-anli",fullName:"Mohamed Anli",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"197120",title:"Mr.",name:"Habib Ur",middleName:null,surname:"Rehman",slug:"habib-ur-rehman",fullName:"Habib Ur Rehman",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"328192",title:"Dr.",name:"Sameer",middleName:null,surname:"Kumar",slug:"sameer-kumar",fullName:"Sameer Kumar",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"1024",title:"Dr.",name:"Keinosuke",middleName:null,surname:"Matsumoto",slug:"keinosuke-matsumoto",fullName:"Keinosuke Matsumoto",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Osaka Prefecture University",country:{name:"Japan"}}},{id:"66560",title:"Dr.",name:"Nicole",middleName:null,surname:"Verrills",slug:"nicole-verrills",fullName:"Nicole Verrills",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Newcastle Australia",country:{name:"Australia"}}},{id:"197632",title:"Ph.D.",name:"Karolína",middleName:null,surname:"Barinková",slug:"karolina-barinkova",fullName:"Karolína Barinková",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Pavol Jozef Šafárik",country:{name:"Slovakia"}}},{id:"328704",title:"Dr.",name:"Esther",middleName:null,surname:"Carrillo-Pérez",slug:"esther-carrillo-perez",fullName:"Esther Carrillo-Pérez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universidad de Sonora",country:{name:"Mexico"}}},{id:"66816",title:"Dr.",name:"Iwao",middleName:null,surname:"Emura",slug:"iwao-emura",fullName:"Iwao Emura",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"67072",title:"Mr.",name:"Matthew",middleName:null,surname:"Lorenzi",slug:"matthew-lorenzi",fullName:"Matthew Lorenzi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"The Bristol-Myers Squibb Children's Hospital",country:{name:"United States of America"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:6674},{group:"region",caption:"Middle and South America",value:2,count:5955},{group:"region",caption:"Africa",value:3,count:2461},{group:"region",caption:"Asia",value:4,count:12719},{group:"region",caption:"Australia and Oceania",value:5,count:1018},{group:"region",caption:"Europe",value:6,count:17724}],offset:12,limit:12,total:134203},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{hasNoEditors:"1",sort:"dateEndThirdStepPublish",src:"EDCMP"},books:[{type:"book",id:"11254",title:"Optical Coherence Tomography",subtitle:null,isOpenForSubmission:!0,hash:"a958c09ceaab1fc44c1dd0a817f48c92",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11254.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11616",title:"Foraging",subtitle:null,isOpenForSubmission:!0,hash:"955b60bb658c8d1a09dd4efc9bf6674b",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11616.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11632",title:"Updated Research on Bacteriophages",subtitle:null,isOpenForSubmission:!0,hash:"d34dfa0d5d10511184f97ddaeef9936b",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11632.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11697",title:"Scoliosis",subtitle:null,isOpenForSubmission:!0,hash:"fa052443744b8f6ba5a87091e373bafe",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11697.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11699",title:"Neonatal Surgery",subtitle:null,isOpenForSubmission:!0,hash:"e52adaee8e54f51c2ba4972daeb410f7",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11699.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11730",title:"Midwifery",subtitle:null,isOpenForSubmission:!0,hash:"95389fcd878d0e929234c441744ba398",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11730.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11773",title:"Archaeology - Challenges and Updates",subtitle:null,isOpenForSubmission:!0,hash:"17d91462fa926279f65164ac0d5641cd",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11773.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11776",title:"Fashion Industry",subtitle:null,isOpenForSubmission:!0,hash:"e8d53d1029a7bccf825aa55d43fecc68",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11776.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11794",title:"Coconut Cultivation",subtitle:null,isOpenForSubmission:!0,hash:"48e1cb42a4162f64cae3a2e777472f21",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11794.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11797",title:"Clostridium difficile",subtitle:null,isOpenForSubmission:!0,hash:"4cb066b44bb8d4a8b93a627de26e3ebf",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11797.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11809",title:"Lagomorpha",subtitle:null,isOpenForSubmission:!0,hash:"1e8fd5779205c16e5797b05455dc5be0",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11809.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11818",title:"Uveitis",subtitle:null,isOpenForSubmission:!0,hash:"f8c178e6f45ba7b500281005b5d5b67a",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11818.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:36},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:8},{group:"topic",caption:"Business, Management and Economics",value:7,count:4},{group:"topic",caption:"Chemistry",value:8,count:16},{group:"topic",caption:"Computer and Information Science",value:9,count:8},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:11},{group:"topic",caption:"Engineering",value:11,count:25},{group:"topic",caption:"Environmental Sciences",value:12,count:5},{group:"topic",caption:"Immunology and Microbiology",value:13,count:8},{group:"topic",caption:"Materials Science",value:14,count:12},{group:"topic",caption:"Mathematics",value:15,count:6},{group:"topic",caption:"Medicine",value:16,count:90},{group:"topic",caption:"Neuroscience",value:18,count:7},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:7},{group:"topic",caption:"Physics",value:20,count:1},{group:"topic",caption:"Psychology",value:21,count:6},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:25},{group:"topic",caption:"Technology",value:24,count:1}],offset:12,limit:12,total:278},popularBooks:{featuredBooks:[{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10195",title:"Serotonin and the CNS",subtitle:"New Developments in Pharmacology and Therapeutics",isOpenForSubmission:!1,hash:"7ed9d96da98233a885bd2869a8056c36",slug:"serotonin-and-the-cns-new-developments-in-pharmacology-and-therapeutics",bookSignature:"Berend Olivier",coverURL:"https://cdn.intechopen.com/books/images_new/10195.jpg",editors:[{id:"71579",title:"Prof.",name:"Berend",middleName:null,surname:"Olivier",slug:"berend-olivier",fullName:"Berend Olivier"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11012",title:"Radiopharmaceuticals",subtitle:"Current Research for Better Diagnosis and Therapy",isOpenForSubmission:!1,hash:"f9046d6f96148b285e776f384991120d",slug:"radiopharmaceuticals-current-research-for-better-diagnosis-and-therapy",bookSignature:"Farid A. Badria",coverURL:"https://cdn.intechopen.com/books/images_new/11012.jpg",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9974",title:"E-Learning and Digital Education in the Twenty-First Century",subtitle:null,isOpenForSubmission:!1,hash:"88b58d66e975df20425fc1dfd22d53aa",slug:"e-learning-and-digital-education-in-the-twenty-first-century",bookSignature:"M. Mahruf C. Shohel",coverURL:"https://cdn.intechopen.com/books/images_new/9974.jpg",editors:[{id:"94099",title:"Dr.",name:"M. Mahruf C.",middleName:null,surname:"Shohel",slug:"m.-mahruf-c.-shohel",fullName:"M. Mahruf C. Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4433},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1677,editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10195",title:"Serotonin and the CNS",subtitle:"New Developments in Pharmacology and Therapeutics",isOpenForSubmission:!1,hash:"7ed9d96da98233a885bd2869a8056c36",slug:"serotonin-and-the-cns-new-developments-in-pharmacology-and-therapeutics",bookSignature:"Berend Olivier",coverURL:"https://cdn.intechopen.com/books/images_new/10195.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1337,editors:[{id:"71579",title:"Prof.",name:"Berend",middleName:null,surname:"Olivier",slug:"berend-olivier",fullName:"Berend Olivier"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1309,editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:847,editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",publishedDate:"June 15th 2022",numberOfDownloads:2273,editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:591,editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:515,editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:413,editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",publishedDate:"June 8th 2022",numberOfDownloads:2194,editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:341,editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"11043",title:"Endometriosis",subtitle:"Recent Advances, New Perspectives and Treatments",isOpenForSubmission:!1,hash:"7baf1c70b11d41400bb9302ae9411ca4",slug:"endometriosis-recent-advances-new-perspectives-and-treatments",bookSignature:"Giovana Ap. Gonçalves",coverURL:"https://cdn.intechopen.com/books/images_new/11043.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"185930",title:"Associate Prof.",name:"Giovana",middleName:null,surname:"Gonçalves",slug:"giovana-goncalves",fullName:"Giovana Gonçalves"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10536",title:"Campylobacter",subtitle:null,isOpenForSubmission:!1,hash:"c4b132b741dd0a2ed539b824ab63965f",slug:"campylobacter",bookSignature:"Guillermo Tellez-Isaias and Saeed El-Ashram",coverURL:"https://cdn.intechopen.com/books/images_new/10536.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"73465",title:"Dr.",name:"Guillermo",middleName:null,surname:"Téllez",slug:"guillermo-tellez",fullName:"Guillermo Téllez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10798",title:"Starch",subtitle:"Evolution and Recent Advances",isOpenForSubmission:!1,hash:"f197f6062c1574a9a90e50a369271bcf",slug:"starch-evolution-and-recent-advances",bookSignature:"Martins Ochubiojo Emeje",coverURL:"https://cdn.intechopen.com/books/images_new/10798.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11083",title:"Hazardous Waste Management",subtitle:null,isOpenForSubmission:!1,hash:"d553bd4f6f1c4b115ca69bd19faac7dc",slug:"hazardous-waste-management",bookSignature:"Rajesh Banu Jeyakumar, Kavitha Sankarapandian and Yukesh Kannah Ravi",coverURL:"https://cdn.intechopen.com/books/images_new/11083.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"218539",title:"Dr.",name:"Rajesh Banu",middleName:null,surname:"Jeyakumar",slug:"rajesh-banu-jeyakumar",fullName:"Rajesh Banu Jeyakumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10848",title:"Tribology of Machine Elements",subtitle:"Fundamentals and Applications",isOpenForSubmission:!1,hash:"3c4ca4c4692ca8d4fa749b4ae81ec1fa",slug:"tribology-of-machine-elements-fundamentals-and-applications",bookSignature:"Giuseppe Pintaude, Tiago Cousseau and Anna Rudawska",coverURL:"https://cdn.intechopen.com/books/images_new/10848.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"18347",title:"Prof.",name:"Giuseppe",middleName:null,surname:"Pintaude",slug:"giuseppe-pintaude",fullName:"Giuseppe Pintaude"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10856",title:"Crude Oil",subtitle:"New Technologies and Recent Approaches",isOpenForSubmission:!1,hash:"8d0a7ca35b3de95b295dc4eab39a087e",slug:"crude-oil-new-technologies-and-recent-approaches",bookSignature:"Manar Elsayed Abdel-Raouf and Mohamed Hasan El-Keshawy",coverURL:"https://cdn.intechopen.com/books/images_new/10856.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"102626",title:"Prof.",name:"Manar",middleName:null,surname:"Elsayed Abdel-Raouf",slug:"manar-elsayed-abdel-raouf",fullName:"Manar Elsayed Abdel-Raouf"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9625",title:"Spinocerebellar Ataxia",subtitle:"Concepts, Particularities and Generalities",isOpenForSubmission:!1,hash:"365a7025fd46eb45de2549bdd9d50b98",slug:"spinocerebellar-ataxia-concepts-particularities-and-generalities",bookSignature:"Patricia Bozzetto Ambrosi",coverURL:"https://cdn.intechopen.com/books/images_new/9625.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"221787",title:"Dr.",name:"Patricia",middleName:null,surname:"Bozzetto Ambrosi",slug:"patricia-bozzetto-ambrosi",fullName:"Patricia Bozzetto Ambrosi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10905",title:"Plant Defense Mechanisms",subtitle:null,isOpenForSubmission:!1,hash:"84ad5b27dde5f01dc76087d0fd6fa834",slug:"plant-defense-mechanisms",bookSignature:"Josphert Ngui Kimatu",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"224171",title:"Prof.",name:"Josphert N.",middleName:null,surname:"Kimatu",slug:"josphert-n.-kimatu",fullName:"Josphert N. Kimatu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10686",title:"Natural Gas",subtitle:"New Perspectives and Future Developments",isOpenForSubmission:!1,hash:"581763788a6a59e653a9d1d9b5a42d79",slug:"natural-gas-new-perspectives-and-future-developments",bookSignature:"Maryam Takht Ravanchi",coverURL:"https://cdn.intechopen.com/books/images_new/10686.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"2416",title:"Dr.",name:"Maryam",middleName:null,surname:"Takht Ravanchi",slug:"maryam-takht-ravanchi",fullName:"Maryam Takht Ravanchi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10988",title:"Railway Transport Planning and Manageme",subtitle:null,isOpenForSubmission:!1,hash:"5cb54cc53caedad9ec78372563c82e2c",slug:"railway-transport-planning-and-management",bookSignature:"Stefano de Luca, Roberta Di Pace and Chiara Fiori",coverURL:"https://cdn.intechopen.com/books/images_new/10988.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"271061",title:"Prof.",name:"Stefano",middleName:null,surname:"de Luca",slug:"stefano-de-luca",fullName:"Stefano de Luca"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"115",title:"Control Engineering",slug:"engineering-control-engineering",parent:{id:"11",title:"Engineering",slug:"engineering"},numberOfBooks:51,numberOfSeries:0,numberOfAuthorsAndEditors:1216,numberOfWosCitations:1462,numberOfCrossrefCitations:1062,numberOfDimensionsCitations:1863,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"115",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"10972",title:"Control Systems in Engineering and Optimization Techniques",subtitle:null,isOpenForSubmission:!1,hash:"f92f65447d0f90b67465865d41a61cd1",slug:"control-systems-in-engineering-and-optimization-techniques",bookSignature:"P. Balasubramaniam, Sathiyaraj Thambiayya, Kuru Ratnavelu and JinRong Wang",coverURL:"https://cdn.intechopen.com/books/images_new/10972.jpg",editedByType:"Edited by",editors:[{id:"252215",title:"Dr.",name:"P.",middleName:null,surname:"Balasubramaniam",slug:"p.-balasubramaniam",fullName:"P. Balasubramaniam"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9976",title:"Fuzzy Systems",subtitle:"Theory and Applications",isOpenForSubmission:!1,hash:"5c4c0d41cf25d2e8fda944450ac46d95",slug:"fuzzy-systems-theory-and-applications",bookSignature:"Constantin Volosencu",coverURL:"https://cdn.intechopen.com/books/images_new/9976.jpg",editedByType:"Edited by",editors:[{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9887",title:"Control Based on PID Framework",subtitle:"The Mutual Promotion of Control and Identification for Complex Systems",isOpenForSubmission:!1,hash:"d2dae75adf13d3e082893264d82967fb",slug:"control-based-on-pid-framework-the-mutual-promotion-of-control-and-identification-for-complex-systems",bookSignature:"Wei Wang",coverURL:"https://cdn.intechopen.com/books/images_new/9887.jpg",editedByType:"Edited by",editors:[{id:"101176",title:"Prof.",name:"Wei",middleName:null,surname:"Wang",slug:"wei-wang",fullName:"Wei Wang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9893",title:"Automation and Control",subtitle:null,isOpenForSubmission:!1,hash:"09ba24f6ac88af7f0aaff3029714ae48",slug:"automation-and-control",bookSignature:"Constantin Voloşencu, Serdar Küçük, José Guerrero and Oscar Valero",coverURL:"https://cdn.intechopen.com/books/images_new/9893.jpg",editedByType:"Edited by",editors:[{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9287",title:"Control Theory in Engineering",subtitle:null,isOpenForSubmission:!1,hash:"7c584de5f40193b636833aa812dab9d5",slug:"control-theory-in-engineering",bookSignature:"Constantin Volosencu, Ali Saghafinia, Xian Du and Sohom Chakrabarty",coverURL:"https://cdn.intechopen.com/books/images_new/9287.jpg",editedByType:"Edited by",editors:[{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8347",title:"Computer Architecture in Industrial, Biomechanical and Biomedical Engineering",subtitle:null,isOpenForSubmission:!1,hash:"3d7024a8d7d8afed093c9c79ec31f15a",slug:"computer-architecture-in-industrial-biomechanical-and-biomedical-engineering",bookSignature:"Lulu Wang and Liandong Yu",coverURL:"https://cdn.intechopen.com/books/images_new/8347.jpg",editedByType:"Edited by",editors:[{id:"257388",title:"Distinguished Prof.",name:"Lulu",middleName:null,surname:"Wang",slug:"lulu-wang",fullName:"Lulu Wang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7485",title:"Applied Modern Control",subtitle:null,isOpenForSubmission:!1,hash:"c7a7be73f7232e08867ed81bdf9850c6",slug:"applied-modern-control",bookSignature:"Le Anh Tuan",coverURL:"https://cdn.intechopen.com/books/images_new/7485.jpg",editedByType:"Edited by",editors:[{id:"180550",title:"Dr.",name:"Le",middleName:null,surname:"Anh Tuan",slug:"le-anh-tuan",fullName:"Le Anh Tuan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6806",title:"Fuzzy Logic Based in Optimization Methods and Control Systems and Its Applications",subtitle:null,isOpenForSubmission:!1,hash:"fedf4479b910cbcee3025e391f073417",slug:"fuzzy-logic-based-in-optimization-methods-and-control-systems-and-its-applications",bookSignature:"Ali Sadollah",coverURL:"https://cdn.intechopen.com/books/images_new/6806.jpg",editedByType:"Edited by",editors:[{id:"147215",title:"Dr.",name:"Ali",middleName:null,surname:"Sadollah",slug:"ali-sadollah",fullName:"Ali Sadollah"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6323",title:"PID Control for Industrial Processes",subtitle:null,isOpenForSubmission:!1,hash:"3994459e0812cf44a04b3f6c3e28e9c1",slug:"pid-control-for-industrial-processes",bookSignature:"Mohammad Shamsuzzoha",coverURL:"https://cdn.intechopen.com/books/images_new/6323.jpg",editedByType:"Edited by",editors:[{id:"87344",title:"Dr.",name:"Mohammad",middleName:null,surname:"Shamsuzzoha",slug:"mohammad-shamsuzzoha",fullName:"Mohammad Shamsuzzoha"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6101",title:"Advances in Some Hypersonic Vehicles Technologies",subtitle:null,isOpenForSubmission:!1,hash:"5ecc3136420d6f6cc0de2da29f9d749c",slug:"advances-in-some-hypersonic-vehicles-technologies",bookSignature:"Ramesh K. Agarwal",coverURL:"https://cdn.intechopen.com/books/images_new/6101.jpg",editedByType:"Edited by",editors:[{id:"38519",title:"Prof.",name:"Ramesh K.",middleName:null,surname:"Agarwal",slug:"ramesh-k.-agarwal",fullName:"Ramesh K. Agarwal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6240",title:"Adaptive Robust Control Systems",subtitle:null,isOpenForSubmission:!1,hash:"19601f78e28ac1956912e5eeb6b834ac",slug:"adaptive-robust-control-systems",bookSignature:"Le Anh Tuan",coverURL:"https://cdn.intechopen.com/books/images_new/6240.jpg",editedByType:"Edited by",editors:[{id:"180551",title:"Prof.",name:"Anh Tuan",middleName:null,surname:"Le",slug:"anh-tuan-le",fullName:"Anh Tuan Le"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5823",title:"Recent Developments in Sliding Mode Control",subtitle:"Theory and Applications",isOpenForSubmission:!1,hash:"1075a2f87196085bae2babfac6bc3d52",slug:"recent-developments-in-sliding-mode-control-theory-and-applications",bookSignature:"Andrzej Bartoszewicz",coverURL:"https://cdn.intechopen.com/books/images_new/5823.jpg",editedByType:"Edited by",editors:[{id:"18337",title:"Prof.",name:"Andrzej",middleName:null,surname:"Bartoszewicz",slug:"andrzej-bartoszewicz",fullName:"Andrzej Bartoszewicz"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:51,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"34221",doi:"10.5772/36321",title:"A Mamdani Type Fuzzy Logic Controller",slug:"a-mamdani-type-fuzzy-logic-controller",totalDownloads:12542,totalCrossrefCites:40,totalDimensionsCites:67,abstract:null,book:{id:"2273",slug:"fuzzy-logic-controls-concepts-theories-and-applications",title:"Fuzzy Logic",fullTitle:"Fuzzy Logic - Controls, Concepts, Theories and Applications"},signatures:"Ion Iancu",authors:[{id:"107854",title:"Prof.",name:"Ion",middleName:null,surname:"Iancu",slug:"ion-iancu",fullName:"Ion Iancu"}]},{id:"29691",doi:"10.5772/37638",title:"A Real-Time Gradient Method for Nonlinear Model Predictive Control",slug:"a-real-time-gradient-method-for-nonlinear-model-predictive-control",totalDownloads:2670,totalCrossrefCites:52,totalDimensionsCites:66,abstract:null,book:{id:"2091",slug:"frontiers-of-model-predictive-control",title:"Frontiers of Model Predictive Control",fullTitle:"Frontiers of Model Predictive Control"},signatures:"Knut Graichen and Bartosz Käpernick",authors:[{id:"113632",title:"Prof.",name:"Knut",middleName:null,surname:"Graichen",slug:"knut-graichen",fullName:"Knut Graichen"},{id:"139321",title:"MSc.",name:"Bartosz",middleName:null,surname:"Kaepernick",slug:"bartosz-kaepernick",fullName:"Bartosz Kaepernick"}]},{id:"62600",doi:"10.5772/intechopen.79552",title:"Introductory Chapter: Which Membership Function is Appropriate in Fuzzy System?",slug:"introductory-chapter-which-membership-function-is-appropriate-in-fuzzy-system-",totalDownloads:1924,totalCrossrefCites:31,totalDimensionsCites:54,abstract:null,book:{id:"6806",slug:"fuzzy-logic-based-in-optimization-methods-and-control-systems-and-its-applications",title:"Fuzzy Logic Based in Optimization Methods and Control Systems and Its Applications",fullTitle:"Fuzzy Logic Based in Optimization Methods and Control Systems and Its Applications"},signatures:"Ali Sadollah",authors:[{id:"147215",title:"Dr.",name:"Ali",middleName:null,surname:"Sadollah",slug:"ali-sadollah",fullName:"Ali Sadollah"}]},{id:"4579",doi:"10.5772/5812",title:"Cumulative Vehicle Routing Problems",slug:"cumulative_vehicle_routing_problems",totalDownloads:3404,totalCrossrefCites:24,totalDimensionsCites:46,abstract:null,book:{id:"5332",slug:"vehicle_routing_problem",title:"Vehicle Routing Problem",fullTitle:"Vehicle Routing Problem"},signatures:"İmdat Kara, Bahar Yetiş Kara and M. Kadri Yetiş",authors:null},{id:"15216",doi:"10.5772/14532",title:"Super-Twisting Sliding Mode in Motion Control Systems",slug:"super-twisting-sliding-mode-in-motion-control-systems",totalDownloads:5831,totalCrossrefCites:19,totalDimensionsCites:40,abstract:null,book:{id:"103",slug:"sliding-mode-control",title:"Sliding Mode Control",fullTitle:"Sliding Mode Control"},signatures:"Jorge Rivera, Luis Garcia, Christian Mora, 0Juan J. Raygoza and Susana Ortega",authors:[{id:"18069",title:"Dr.",name:"Jorge",middleName:null,surname:"Rivera",slug:"jorge-rivera",fullName:"Jorge Rivera"},{id:"22689",title:"Prof.",name:"Luis",middleName:null,surname:"Garcia",slug:"luis-garcia",fullName:"Luis Garcia"},{id:"22690",title:"Prof.",name:"Christian",middleName:null,surname:"Mora",slug:"christian-mora",fullName:"Christian Mora"},{id:"23671",title:"Dr.",name:"Juan José",middleName:null,surname:"Raygoza",slug:"juan-jose-raygoza",fullName:"Juan José Raygoza"},{id:"23672",title:"Dr.",name:"Susana",middleName:null,surname:"Ortega",slug:"susana-ortega",fullName:"Susana Ortega"}]}],mostDownloadedChaptersLast30Days:[{id:"53024",title:"Key Aspects for Implementing ISO/IEC 17025 Quality Management Systems at Materials Science Laboratories",slug:"key-aspects-for-implementing-iso-iec-17025-quality-management-systems-at-materials-science-laborator",totalDownloads:2823,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Implementing a quality management system based on the requirements specified in ISO/IEC 17025 standard at materials science laboratories is challenging, mainly due to two main factors: (i) the high technical complexity degree of some tests used for materials characterization and (ii) the fact that most materials science laboratories provide materials characterization tests and also carry out research and development activities. In this context, this chapter presents key subjects while implementing a quality management system at materials science laboratories and some considerations on strategies for effectively implementing such systems.",book:{id:"5486",slug:"quality-control-and-assurance-an-ancient-greek-term-re-mastered",title:"Quality Control and Assurance",fullTitle:"Quality Control and Assurance - An Ancient Greek Term Re-Mastered"},signatures:"Rodrigo S. Neves, Daniel P. Da Silva, Carlos E. C. Galhardo, Erlon H.\nM. Ferreira, Rafael M. Trommer and Jailton C. Damasceno",authors:[{id:"20571",title:"Prof.",name:"Erlon H.",middleName:null,surname:"Martins Ferreira",slug:"erlon-h.-martins-ferreira",fullName:"Erlon H. Martins Ferreira"},{id:"145815",title:"Dr.",name:"Rodrigo",middleName:null,surname:"De Santis Neves",slug:"rodrigo-de-santis-neves",fullName:"Rodrigo De Santis Neves"},{id:"145816",title:"Dr.",name:"Carlos",middleName:null,surname:"Eduardo Cardoso Galhardo",slug:"carlos-eduardo-cardoso-galhardo",fullName:"Carlos Eduardo Cardoso Galhardo"},{id:"159056",title:"Dr.",name:"Jailton",middleName:null,surname:"Damasceno",slug:"jailton-damasceno",fullName:"Jailton Damasceno"},{id:"191863",title:"Dr.",name:"Daniel",middleName:"Pereira Da Silva",surname:"Fernandes",slug:"daniel-fernandes",fullName:"Daniel Fernandes"},{id:"191865",title:"Dr.",name:"Rafael",middleName:null,surname:"Mello Trommer",slug:"rafael-mello-trommer",fullName:"Rafael Mello Trommer"}]},{id:"53946",title:"The Evolution of Quality Concepts and the Related Quality Management",slug:"the-evolution-of-quality-concepts-and-the-related-quality-management",totalDownloads:4438,totalCrossrefCites:5,totalDimensionsCites:6,abstract:"Enterprises usually adopt some quality practices to control the product quality during the manufacturing process in order to assure the delivery of qualitative good products to customers. The quality practices or quality management systems adopted by industries will further evolve due to the changes of quality concepts as time goes by. This chapter discusses the change of quality concepts and the related revolution of quality management systems in the past century. The quality concepts were gradually changed from the achievement of quality standards, satisfaction of customer needs, and expectations to customer delight. Since merely satisfying customers is not enough to ensure customer loyalty, the enterprises gradually focus on customers’ emotional responses and their delight in order to pursue their loyalty. The emotion of “delight” is composed of “joy” and “surprise,” which can be achieved as the customers’ latent requirements are satisfied. Thus, the concept of “customer delight” and the means to provide the innovative quality so as to meet the unsatisfied customers’ latent needs are elaborated on. Finally, a framework of innovation creation is developed that is based on the mining of customer's latent requirements. This outline will manifest the essential elements of the related operation steps.",book:{id:"5486",slug:"quality-control-and-assurance-an-ancient-greek-term-re-mastered",title:"Quality Control and Assurance",fullTitle:"Quality Control and Assurance - An Ancient Greek Term Re-Mastered"},signatures:"Ching-Chow Yang",authors:[{id:"11862",title:"Prof.",name:"Ching-Chow",middleName:null,surname:"Yang",slug:"ching-chow-yang",fullName:"Ching-Chow Yang"}]},{id:"62915",title:"Advanced Methods of PID Controller Tuning for Specified Performance",slug:"advanced-methods-of-pid-controller-tuning-for-specified-performance",totalDownloads:3476,totalCrossrefCites:10,totalDimensionsCites:16,abstract:"This chapter provides a concise survey, classification and historical perspective of practice-oriented methods for designing proportional-integral-derivative (PID) controllers and autotuners showing the persistent demand for PID tuning algorithms that integrate performance requirements into the tuning algorithm. The proposed frequency-domain PID controller design method guarantees closed-loop performance in terms of commonly used time-domain specifications. One of its major benefits is universal applicability for both slow and fast-controlled plants with unknown mathematical model. Special charts called B-parabolas were developed as a practical design tool that enables consistent and systematic shaping of the closed-loop step response with regard to specified performance and dynamics of the uncertain controlled plant.",book:{id:"6323",slug:"pid-control-for-industrial-processes",title:"PID Control for Industrial Processes",fullTitle:"PID Control for Industrial Processes"},signatures:"Štefan Bucz and Alena Kozáková",authors:[{id:"21933",title:"Ms.",name:"Alena",middleName:null,surname:"Kozakova",slug:"alena-kozakova",fullName:"Alena Kozakova"},{id:"213658",title:"Dr.",name:"Štefan",middleName:null,surname:"Bucz",slug:"stefan-bucz",fullName:"Štefan Bucz"}]},{id:"75699",title:"Data Clustering for Fuzzyfier Value Derivation",slug:"data-clustering-for-fuzzyfier-value-derivation",totalDownloads:292,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The fuzzifier value m is improving significant factor for achieving the accuracy of data. Therefore, in this chapter, various clustering method is introduced with the definition of important values for clustering. To adaptively calculate the appropriate purge value of the gap type −2 fuzzy c-means, two fuzzy values m1 and m2 are provided by extracting information from individual data points using a histogram scheme. Most of the clustering in this chapter automatically obtains determination of m1 and m2 values that depended on existent repeated experiments. Also, in order to increase efficiency on deriving valid fuzzifier value, we introduce the Interval type-2 possibilistic fuzzy C-means (IT2PFCM), as one of advanced fuzzy clustering method to classify a fixed pattern. In Efficient IT2PFCM method, proper fuzzifier values for each data is obtained from an algorithm including histogram analysis and Gaussian Curve Fitting method. Using the extracted information form fuzzifier values, two modified fuzzifier value m1 and m2 are determined. These updated fuzzifier values are used to calculated the new membership values. Determining these updated values improve not only the clustering accuracy rate of the measured sensor data, but also can be used without additional procedure such as data labeling. It is also efficient at monitoring numerous sensors, managing and verifying sensor data obtained in real time such as smart cities.",book:{id:"9976",slug:"fuzzy-systems-theory-and-applications",title:"Fuzzy Systems",fullTitle:"Fuzzy Systems - Theory and Applications"},signatures:"JaeHyuk Cho",authors:[{id:"329648",title:"Prof.",name:"JaeHyuk",middleName:null,surname:"Cho",slug:"jaehyuk-cho",fullName:"JaeHyuk Cho"}]},{id:"39778",title:"GPS and the One-Way Speed of Light",slug:"gps-and-the-one-way-speed-of-light",totalDownloads:3478,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"2387",slug:"new-approach-of-indoor-and-outdoor-localization-systems",title:"New Approach of Indoor and Outdoor Localization Systems",fullTitle:"New Approach of Indoor and Outdoor Localization Systems"},signatures:"Stephan J.G. Gift",authors:[{id:"141106",title:"Prof.",name:"Stephan",middleName:null,surname:"Gift",slug:"stephan-gift",fullName:"Stephan Gift"}]}],onlineFirstChaptersFilter:{topicId:"115",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"77466",title:"Optimization of Model Predictive Control Weights for Control of Permanent Magnet Synchronous Motor by Using the Multi Objective Bees Algorithm",slug:"optimization-of-model-predictive-control-weights-for-control-of-permanent-magnet-synchronous-motor-b",totalDownloads:142,totalDimensionsCites:0,doi:"10.5772/intechopen.98810",abstract:"In this study, the model predictive control (MPC) method was used within the scope of the control of the permanent magnet synchronous motor (PMSM). The strongest aspect of the MPC, the ability to control multiple components with a single function, is also one of the most difficult parts of its design. The fact that each component of the function has different effects requires assigning different weight coefficients to these components. In this study, the Bees Algorithm (BA) is used to determine the weights. Using the multi-objective function in BA, it has been tried to determine the weights that reduce the current values together with the speed error. Three different PI controllers have been designed to compare the MPC method. The coefficients of one of these are tuned with BA. Good Gain Method and Tyreus-Luyben Method were used in the other two. As a result of experimental studies, it has been observed that MPC can control PMSM more smoothly and accurately than PI controllers, with weights optimized with BA. With MPC, PMSM has been controlled with 15% settling time than other controllers and also with no overshoot.",book:{id:"10778",title:"Model-Based Control Engineering - Recent Design and Implementations for Varied Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10778.jpg"},signatures:"Murat Sahin"},{id:"78164",title:"Use of Discrete-Time Forecast Modeling to Enhance Feedback Control and Physically Unrealizable Feedforward Control with Applications",slug:"use-of-discrete-time-forecast-modeling-to-enhance-feedback-control-and-physically-unrealizable-feedf",totalDownloads:67,totalDimensionsCites:0,doi:"10.5772/intechopen.99340",abstract:"When the manipulated variable (MV) has significantly large time delay in changing the control variable (CV), use of the currently measured CV in the feedback error can result in very deficient feedback control (FBC). However, control strategies that use forecast modeling to estimate future CV values and use them in the feedback error have the potential to control as well as a feedback controller with no MV deadtime using the measured value of CV. This work evaluates and compares FBC algorithms using discrete-time forecast modeling when MV has a large deadtime. When a feedforward control (FFC) law results in a physically unrealizable (PU) controller, the common approach is to use approximations to obtain a physically realizable feedforward controller. Using a discrete-time forecast modeling method, this work demonstrates an effective approach for PU FFC. The Smith Predictor is a popular control strategy when CV has measurement deadtime but not MV deadtime. The work demonstrates equivalency of this discrete-time forecast modeling approach to the Smith Predictor FBC approach. Thus, this work demonstrates effectiveness of the discrete-time forecast modeling approach for FBC with MV or DV deadtime and PU FFC.",book:{id:"10778",title:"Model-Based Control Engineering - Recent Design and Implementations for Varied Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10778.jpg"},signatures:"Derrick K. Rollins"}],onlineFirstChaptersTotal:2},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:320,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:133,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:16,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"6",title:"Infectious Diseases",doi:"10.5772/intechopen.71852",issn:"2631-6188",scope:"This series will provide a comprehensive overview of recent research trends in various Infectious Diseases (as per the most recent Baltimore classification). Topics will include general overviews of infections, immunopathology, diagnosis, treatment, epidemiology, etiology, and current clinical recommendations for managing infectious diseases. Ongoing issues, recent advances, and future diagnostic approaches and therapeutic strategies will also be discussed. This book series will focus on various aspects and properties of infectious diseases whose deep understanding is essential for safeguarding the human race from losing resources and economies due to pathogens.",coverUrl:"https://cdn.intechopen.com/series/covers/6.jpg",latestPublicationDate:"June 25th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:13,editor:{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"3",title:"Bacterial Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/3.jpg",isOpenForSubmission:!1,editor:null,editorTwo:null,editorThree:null},{id:"4",title:"Fungal Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/4.jpg",isOpenForSubmission:!0,editor:{id:"174134",title:"Dr.",name:"Yuping",middleName:null,surname:"Ran",slug:"yuping-ran",fullName:"Yuping Ran",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9d6QAC/Profile_Picture_1630330675373",biography:"Dr. Yuping Ran, Professor, Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China. Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. Board Member and Chair of Mycology Group of Chinese Society of Dermatology.",institutionString:null,institution:{name:"Sichuan University",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null},{id:"5",title:"Parasitic Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",isOpenForSubmission:!0,editor:{id:"67907",title:"Dr.",name:"Amidou",middleName:null,surname:"Samie",slug:"amidou-samie",fullName:"Amidou Samie",profilePictureURL:"https://mts.intechopen.com/storage/users/67907/images/system/67907.jpg",biography:"Dr. Amidou Samie is an Associate Professor of Microbiology at the University of Venda, in South Africa, where he graduated for his PhD in May 2008. He joined the Department of Microbiology the same year and has been giving lectures on topics covering parasitology, immunology, molecular biology and industrial microbiology. He is currently a rated researcher by the National Research Foundation of South Africa at category C2. He has published widely in the field of infectious diseases and has overseen several MSc’s and PhDs. His research activities mostly cover topics on infectious diseases from epidemiology to control. His particular interest lies in the study of intestinal protozoan parasites and opportunistic infections among HIV patients as well as the potential impact of childhood diarrhoea on growth and child development. He also conducts research on water-borne diseases and water quality and is involved in the evaluation of point-of-use water treatment technologies using silver and copper nanoparticles in collaboration with the University of Virginia, USA. He also studies the use of medicinal plants for the control of infectious diseases as well as antimicrobial drug resistance.",institutionString:null,institution:{name:"University of Venda",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},{id:"6",title:"Viral Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/6.jpg",isOpenForSubmission:!0,editor:{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:10,paginationItems:[{id:"82380",title:"Evolution of Parasitism and Pathogenic Adaptations in Certain Medically Important Fungi",doi:"10.5772/intechopen.105206",signatures:"Gokul Shankar Sabesan, Ranjit Singh AJA, Ranjith Mehenderkar and Basanta Kumar Mohanty",slug:"evolution-of-parasitism-and-pathogenic-adaptations-in-certain-medically-important-fungi",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fungal Infectious Diseases - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11400.jpg",subseries:{id:"4",title:"Fungal Infectious Diseases"}}},{id:"82367",title:"Spatial Variation and Factors Associated with Unsuppressed HIV Viral Load among Women in an HIV Hyperendemic Area of KwaZulu-Natal, South Africa",doi:"10.5772/intechopen.105547",signatures:"Adenike O. Soogun, Ayesha B.M. Kharsany, Temesgen Zewotir and Delia North",slug:"spatial-variation-and-factors-associated-with-unsuppressed-hiv-viral-load-among-women-in-an-hiv-hype",totalDownloads:12,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82193",title:"Enterococcal Infections: Recent Nomenclature and emerging trends",doi:"10.5772/intechopen.104792",signatures:"Kavita Raja",slug:"enterococcal-infections-recent-nomenclature-and-emerging-trends",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"82207",title:"Management Strategies in Perinatal HIV",doi:"10.5772/intechopen.105451",signatures:"Kayla Aleshire and Rima Bazzi",slug:"management-strategies-in-perinatal-hiv",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}}]},overviewPagePublishedBooks:{paginationCount:13,paginationItems:[{type:"book",id:"6667",title:"Influenza",subtitle:"Therapeutics and Challenges",coverURL:"https://cdn.intechopen.com/books/images_new/6667.jpg",slug:"influenza-therapeutics-and-challenges",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"105e347b2d5dbbe6b593aceffa051efa",volumeInSeries:1,fullTitle:"Influenza - Therapeutics and Challenges",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}]},{type:"book",id:"7064",title:"Current Perspectives in Human Papillomavirus",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7064.jpg",slug:"current-perspectives-in-human-papillomavirus",publishedDate:"May 2nd 2019",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"d92a4085627bab25ddc7942fbf44cf05",volumeInSeries:2,fullTitle:"Current Perspectives in Human Papillomavirus",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}]},{type:"book",id:"7123",title:"Current Topics in Neglected Tropical Diseases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7123.jpg",slug:"current-topics-in-neglected-tropical-diseases",publishedDate:"December 4th 2019",editedByType:"Edited by",bookSignature:"Alfonso J. Rodriguez-Morales",hash:"61c627da05b2ace83056d11357bdf361",volumeInSeries:3,fullTitle:"Current Topics in Neglected Tropical Diseases",editors:[{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null}]},{type:"book",id:"7839",title:"Malaria",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7839.jpg",slug:"malaria",publishedDate:"December 11th 2019",editedByType:"Edited by",bookSignature:"Fyson H. Kasenga",hash:"91cde4582ead884cb0f355a19b67cd56",volumeInSeries:4,fullTitle:"Malaria",editors:[{id:"86725",title:"Dr.",name:"Fyson",middleName:"Hanania",surname:"Kasenga",slug:"fyson-kasenga",fullName:"Fyson Kasenga",profilePictureURL:"https://mts.intechopen.com/storage/users/86725/images/system/86725.jpg",biography:"Dr. Kasenga is a graduate of Tumaini University, Kilimanjaro Christian Medical College, Moshi, Tanzania and Umeå University, Sweden. He obtained a Master’s degree in Public Health and PhD in Public Health and Epidemiology. He has a background in Clinical Medicine and has taken courses at higher diploma levels in public health from University of Transkei, Republic of South Africa, and African Medical and Research Foundation (AMREF) in Nairobi, Kenya. Dr. Kasenga worked in different places in and outside Malawi, and has held various positions, such as Licensed Medical Officer, HIV/AIDS Programme Officer, HIV/AIDS resource person in the International Department of Diakonhjemet College, Oslo, Norway. He also managed an Integrated HIV/AIDS Prevention programme for over 5 years. He is currently working as a Director for the Health Ministries Department of Malawi Union of the Seventh Day Adventist Church. Dr. Kasenga has published over 5 articles on HIV/AIDS issues focusing on Prevention of Mother to Child Transmission of HIV (PMTCT), including a book chapter on HIV testing counseling (currently in press). Dr. Kasenga is married to Grace and blessed with three children, a son and two daughters: Happy, Lettice and Sungani.",institutionString:"Malawi Adventist University",institution:{name:"Malawi Adventist University",institutionURL:null,country:{name:"Malawi"}}}]}]},openForSubmissionBooks:{paginationCount:3,paginationItems:[{id:"11446",title:"Industry 4.0 - Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11446.jpg",hash:"be984f45b90c1003798661ef885d8a34",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"May 12th 2022",isOpenForSubmission:!0,editors:[{id:"303193",title:"Dr.",name:"Meisam",surname:"Gordan",slug:"meisam-gordan",fullName:"Meisam Gordan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11448",title:"Artificial Neural Networks - Recent Advances, New Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11448.jpg",hash:"e57ff97a39cfc6fe68a1ac62b503dbe9",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"June 3rd 2022",isOpenForSubmission:!0,editors:[{id:"22866",title:"Dr.",name:"Chi Leung Patrick",surname:"Hui",slug:"chi-leung-patrick-hui",fullName:"Chi Leung Patrick Hui"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11447",title:"Swarm Intelligence - Recent Advances and Current Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11447.jpg",hash:"f68e3c3430a74fc7a7eb97f6ea2bb42e",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"July 22nd 2022",isOpenForSubmission:!0,editors:[{id:"24555",title:"Dr.",name:"Marco Antonio",surname:"Aceves Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves Fernandez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:5,paginationItems:[{id:"82394",title:"Learning by Doing Active Social Learning",doi:"10.5772/intechopen.105523",signatures:"Anat Raviv",slug:"learning-by-doing-active-social-learning",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}},{id:"82310",title:"Knowledge of Intergenerational Contact to Combat Ageism towards Older People",doi:"10.5772/intechopen.105592",signatures:"Alice Nga Lai Kwong",slug:"knowledge-of-intergenerational-contact-to-combat-ageism-towards-older-people",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Social Aspects of Ageing - Selected Challenges, Analyses, and Solutions",coverURL:"https://cdn.intechopen.com/books/images_new/11479.jpg",subseries:{id:"90",title:"Human Development"}}},{id:"81993",title:"Emergent Chemistry: Using Visualizations to Develop Abstract Thinking and a Sense of Scale Within the Preschool Setting",doi:"10.5772/intechopen.105216",signatures:"Karina Adbo",slug:"emergent-chemistry-using-visualizations-to-develop-abstract-thinking-and-a-sense-of-scale-within-the",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}},{id:"82252",title:"Early Childhood: Enriched Environments and Roles of Caring Adults",doi:"10.5772/intechopen.105157",signatures:"Analía Mignaton",slug:"early-childhood-enriched-environments-and-roles-of-caring-adults",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}},{id:"81996",title:"Perspective Chapter: New Active Learning Models in Africa",doi:"10.5772/intechopen.105217",signatures:"Fred Awaah, Cosmas Lambini Kombat and Emmanuel Okyere Ekwam",slug:"perspective-chapter-new-active-learning-models-in-africa",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}}]},subseriesFiltersForOFChapters:[{caption:"Human Development",value:90,count:1,group:"subseries"},{caption:"Education",value:89,count:4,group:"subseries"}],publishedBooks:{paginationCount:8,paginationItems:[{type:"book",id:"9493",title:"Periodontology",subtitle:"Fundamentals and Clinical Features",coverURL:"https://cdn.intechopen.com/books/images_new/9493.jpg",slug:"periodontology-fundamentals-and-clinical-features",publishedDate:"February 16th 2022",editedByType:"Edited by",bookSignature:"Petra Surlin",hash:"dfe986c764d6c82ae820c2df5843a866",volumeInSeries:8,fullTitle:"Periodontology - Fundamentals and Clinical Features",editors:[{id:"171921",title:"Prof.",name:"Petra",middleName:null,surname:"Surlin",slug:"petra-surlin",fullName:"Petra Surlin",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:"University of Medicine and Pharmacy of Craiova",institution:{name:"University of Medicine and Pharmacy of Craiova",institutionURL:null,country:{name:"Romania"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9588",title:"Clinical Concepts and Practical Management Techniques in Dentistry",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9588.jpg",slug:"clinical-concepts-and-practical-management-techniques-in-dentistry",publishedDate:"February 9th 2022",editedByType:"Edited by",bookSignature:"Aneesa Moolla",hash:"42deab8d3bcf3edf64d1d9028d42efd1",volumeInSeries:7,fullTitle:"Clinical Concepts and Practical Management Techniques in Dentistry",editors:[{id:"318170",title:"Dr.",name:"Aneesa",middleName:null,surname:"Moolla",slug:"aneesa-moolla",fullName:"Aneesa Moolla",profilePictureURL:"https://mts.intechopen.com/storage/users/318170/images/system/318170.png",institutionString:"University of the Witwatersrand",institution:{name:"University of the Witwatersrand",institutionURL:null,country:{name:"South Africa"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8202",title:"Periodontal Disease",subtitle:"Diagnostic and Adjunctive Non-surgical Considerations",coverURL:"https://cdn.intechopen.com/books/images_new/8202.jpg",slug:"periodontal-disease-diagnostic-and-adjunctive-non-surgical-considerations",publishedDate:"February 5th 2020",editedByType:"Edited by",bookSignature:"Nermin Mohammed Ahmed Yussif",hash:"0aee9799da7db2c732be44dd8fed16d8",volumeInSeries:6,fullTitle:"Periodontal Disease - Diagnostic and Adjunctive Non-surgical Considerations",editors:[{id:"210472",title:"Dr.",name:"Nermin",middleName:"Mohammed Ahmed",surname:"Yussif",slug:"nermin-yussif",fullName:"Nermin Yussif",profilePictureURL:"https://mts.intechopen.com/storage/users/210472/images/system/210472.jpg",institutionString:"MSA University",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8837",title:"Human Teeth",subtitle:"Key Skills and Clinical Illustrations",coverURL:"https://cdn.intechopen.com/books/images_new/8837.jpg",slug:"human-teeth-key-skills-and-clinical-illustrations",publishedDate:"January 22nd 2020",editedByType:"Edited by",bookSignature:"Zühre Akarslan and Farid Bourzgui",hash:"ac055c5801032970123e0a196c2e1d32",volumeInSeries:5,fullTitle:"Human Teeth - Key Skills and Clinical Illustrations",editors:[{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",institutionString:"Gazi University",institution:{name:"Gazi University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:{id:"52177",title:"Prof.",name:"Farid",middleName:null,surname:"Bourzgui",slug:"farid-bourzgui",fullName:"Farid Bourzgui",profilePictureURL:"https://mts.intechopen.com/storage/users/52177/images/system/52177.png",biography:"Prof. Farid Bourzgui obtained his DMD and his DNSO option in Orthodontics at the School of Dental Medicine, Casablanca Hassan II University, Morocco, in 1995 and 2000, respectively. Currently, he is a professor of Orthodontics. He holds a Certificate of Advanced Study type A in Technology of Biomaterials used in Dentistry (1995); Certificate of Advanced Study type B in Dento-Facial Orthopaedics (1997) from the Faculty of Dental Surgery, University Denis Diderot-Paris VII, France; Diploma of Advanced Study (DESA) in Biocompatibility of Biomaterials from the Faculty of Medicine and Pharmacy of Casablanca (2002); Certificate of Clinical Occlusodontics from the Faculty of Dentistry of Casablanca (2004); University Diploma of Biostatistics and Perceptual Health Measurement from the Faculty of Medicine and Pharmacy of Casablanca (2011); and a University Diploma of Pedagogy of Odontological Sciences from the Faculty of Dentistry of Casablanca (2013). He is the author of several scientific articles, book chapters, and books.",institutionString:"University of Hassan II Casablanca",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"7",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"University of Hassan II Casablanca",institutionURL:null,country:{name:"Morocco"}}},equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7060",title:"Gingival Disease",subtitle:"A Professional Approach for Treatment and Prevention",coverURL:"https://cdn.intechopen.com/books/images_new/7060.jpg",slug:"gingival-disease-a-professional-approach-for-treatment-and-prevention",publishedDate:"October 23rd 2019",editedByType:"Edited by",bookSignature:"Alaa Eddin Omar Al Ostwani",hash:"b81d39988cba3a3cf746c1616912cf41",volumeInSeries:4,fullTitle:"Gingival Disease - A Professional Approach for Treatment and Prevention",editors:[{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7572",title:"Trauma in Dentistry",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7572.jpg",slug:"trauma-in-dentistry",publishedDate:"July 3rd 2019",editedByType:"Edited by",bookSignature:"Serdar Gözler",hash:"7cb94732cfb315f8d1e70ebf500eb8a9",volumeInSeries:3,fullTitle:"Trauma in Dentistry",editors:[{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7139",title:"Current Approaches in Orthodontics",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7139.jpg",slug:"current-approaches-in-orthodontics",publishedDate:"April 10th 2019",editedByType:"Edited by",bookSignature:"Belma Işık Aslan and Fatma Deniz Uzuner",hash:"2c77384eeb748cf05a898d65b9dcb48a",volumeInSeries:2,fullTitle:"Current Approaches in Orthodontics",editors:[{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"6668",title:"Dental Caries",subtitle:"Diagnosis, Prevention and Management",coverURL:"https://cdn.intechopen.com/books/images_new/6668.jpg",slug:"dental-caries-diagnosis-prevention-and-management",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Zühre Akarslan",hash:"b0f7667770a391f772726c3013c1b9ba",volumeInSeries:1,fullTitle:"Dental Caries - Diagnosis, Prevention and Management",editors:[{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",institutionString:"Gazi University",institution:{name:"Gazi University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Prosthodontics and Implant Dentistry",value:2,count:2},{group:"subseries",caption:"Oral Health",value:1,count:6}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:2},{group:"publicationYear",caption:"2020",value:2020,count:2},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:229,paginationItems:[{id:"318170",title:"Dr.",name:"Aneesa",middleName:null,surname:"Moolla",slug:"aneesa-moolla",fullName:"Aneesa Moolla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/318170/images/system/318170.png",biography:"Dr. Aneesa Moolla has extensive experience in the diverse fields of health care having previously worked in dental private practice, at the Red Cross Flying Doctors association, and in healthcare corporate settings. She is now a lecturer at the University of Witwatersrand, South Africa, and a principal researcher at the Health Economics and Epidemiology Research Office (HE2RO), South Africa. Dr. Moolla holds a Ph.D. in Psychology with her research being focused on mental health and resilience. In her professional work capacity, her research has further expanded into the fields of early childhood development, mental health, the HIV and TB care cascades, as well as COVID. She is also a UNESCO-trained International Bioethics Facilitator.",institutionString:"University of the Witwatersrand",institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419588",title:"Ph.D.",name:"Sergio",middleName:"Alexandre",surname:"Gehrke",slug:"sergio-gehrke",fullName:"Sergio Gehrke",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038WgMKQA0/Profile_Picture_2022-06-02T11:44:20.jpg",biography:"Dr. Sergio Alexandre Gehrke is a doctorate holder in two fields. The first is a Ph.D. in Cellular and Molecular Biology from the Pontificia Catholic University, Porto Alegre, Brazil, in 2010 and the other is an International Ph.D. in Bioengineering from the Universidad Miguel Hernandez, Elche/Alicante, Spain, obtained in 2020. In 2018, he completed a postdoctoral fellowship in Materials Engineering in the NUCLEMAT of the Pontificia Catholic University, Porto Alegre, Brazil. He is currently the Director of the Postgraduate Program in Implantology of the Bioface/UCAM/PgO (Montevideo, Uruguay), Director of the Cathedra of Biotechnology of the Catholic University of Murcia (Murcia, Spain), an Extraordinary Full Professor of the Catholic University of Murcia (Murcia, Spain) as well as the Director of the private center of research Biotecnos – Technology and Science (Montevideo, Uruguay). Applied biomaterials, cellular and molecular biology, and dental implants are among his research interests. He has published several original papers in renowned journals. In addition, he is also a Collaborating Professor in several Postgraduate programs at different universities all over the world.",institutionString:null,institution:{name:"Universidad Católica San Antonio de Murcia",country:{name:"Spain"}}},{id:"342152",title:"Dr.",name:"Santo",middleName:null,surname:"Grace Umesh",slug:"santo-grace-umesh",fullName:"Santo Grace Umesh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/342152/images/16311_n.jpg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"333647",title:"Dr.",name:"Shreya",middleName:null,surname:"Kishore",slug:"shreya-kishore",fullName:"Shreya Kishore",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333647/images/14701_n.jpg",biography:"Dr. Shreya Kishore completed her Bachelor in Dental Surgery in Chettinad Dental College and Research Institute, Chennai, and her Master of Dental Surgery (Orthodontics) in Saveetha Dental College, Chennai. She is also Invisalign certified. She’s working as a Senior Lecturer in the Department of Orthodontics, SRM Dental College since November 2019. She is actively involved in teaching orthodontics to the undergraduates and the postgraduates. Her clinical research topics include new orthodontic brackets, fixed appliances and TADs. She’s published 4 articles in well renowned indexed journals and has a published patency of her own. Her private practice is currently limited to orthodontics and works as a consultant in various clinics.",institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"323731",title:"Prof.",name:"Deepak M.",middleName:"Macchindra",surname:"Vikhe",slug:"deepak-m.-vikhe",fullName:"Deepak M. Vikhe",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/323731/images/13613_n.jpg",biography:"Dr Deepak M.Vikhe .\n\n\t\n\tDr Deepak M.Vikhe , completed his Masters & PhD in Prosthodontics from Rural Dental College, Loni securing third rank in the Pravara Institute of Medical Sciences Deemed University. He was awarded Dr.G.C.DAS Memorial Award for Research on Implants at 39th IPS conference Dubai (U A E).He has two patents under his name. He has received Dr.Saraswati medal award for best research for implant study in 2017.He has received Fully funded scholarship to Spain ,university of Santiago de Compostela. He has completed fellowship in Implantlogy from Noble Biocare. \nHe has attended various conferences and CDE programmes and has national publications to his credit. His field of interest is in Implant supported prosthesis. Presently he is working as a associate professor in the Dept of Prosthodontics, Rural Dental College, Loni and maintains a successful private practice specialising in Implantology at Rahata.\n\nEmail: drdeepak_mvikhe@yahoo.com..................",institutionString:null,institution:{name:"Pravara Institute of Medical Sciences",country:{name:"India"}}},{id:"204110",title:"Dr.",name:"Ahmed A.",middleName:null,surname:"Madfa",slug:"ahmed-a.-madfa",fullName:"Ahmed A. Madfa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204110/images/system/204110.jpg",biography:"Dr. Madfa is currently Associate Professor of Endodontics at Thamar University and a visiting lecturer at Sana'a University and University of Sciences and Technology. He has more than 6 years of experience in teaching. His research interests include root canal morphology, functionally graded concept, dental biomaterials, epidemiology and dental education, biomimetic restoration, finite element analysis and endodontic regeneration. Dr. Madfa has numerous international publications, full articles, two patents, a book and a book chapter. Furthermore, he won 14 international scientific awards. Furthermore, he is involved in many academic activities ranging from editorial board member, reviewer for many international journals and postgraduate students' supervisor. Besides, I deliver many courses and training workshops at various scientific events. Dr. Madfa also regularly attends international conferences and holds administrative positions (Deputy Dean of the Faculty for Students’ & Academic Affairs and Deputy Head of Research Unit).",institutionString:"Thamar University",institution:null},{id:"210472",title:"Dr.",name:"Nermin",middleName:"Mohammed Ahmed",surname:"Yussif",slug:"nermin-yussif",fullName:"Nermin Yussif",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210472/images/system/210472.jpg",biography:"Dr. Nermin Mohammed Ahmed Yussif is working at the Faculty of dentistry, University for October university for modern sciences and arts (MSA). Her areas of expertise include: periodontology, dental laserology, oral implantology, periodontal plastic surgeries, oral mesotherapy, nutrition, dental pharmacology. She is an editor and reviewer in numerous international journals.",institutionString:"MSA University",institution:null},{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. He is also a Member of the Reviewer Board of International Journal of Dental Medicine (IJDM), and the Indian Journal of Conservative and Endodontics since 2016.",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",country:{name:"India"}}},{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null},{id:"178412",title:"Associate Prof.",name:"Guhan",middleName:null,surname:"Dergin",slug:"guhan-dergin",fullName:"Guhan Dergin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178412/images/6954_n.jpg",biography:"Assoc. Prof. Dr. Gühan Dergin was born in 1973 in Izmit. He graduated from Marmara University Faculty of Dentistry in 1999. He completed his specialty of OMFS surgery in Marmara University Faculty of Dentistry and obtained his PhD degree in 2006. In 2005, he was invited as a visiting doctor in the Oral and Maxillofacial Surgery Department of the University of North Carolina, USA, where he went on a scholarship. Dr. Dergin still continues his academic career as an associate professor in Marmara University Faculty of Dentistry. He has many articles in international and national scientific journals and chapters in books.",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"178414",title:"Prof.",name:"Yusuf",middleName:null,surname:"Emes",slug:"yusuf-emes",fullName:"Yusuf Emes",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178414/images/6953_n.jpg",biography:"Born in Istanbul in 1974, Dr. Emes graduated from Istanbul University Faculty of Dentistry in 1997 and completed his PhD degree in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery in 2005. He has papers published in international and national scientific journals, including research articles on implantology, oroantral fistulas, odontogenic cysts, and temporomandibular disorders. Dr. Emes is currently working as a full-time academic staff in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery.",institutionString:null,institution:{name:"Istanbul University",country:{name:"Turkey"}}},{id:"192229",title:"Ph.D.",name:"Ana Luiza",middleName:null,surname:"De Carvalho Felippini",slug:"ana-luiza-de-carvalho-felippini",fullName:"Ana Luiza De Carvalho Felippini",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192229/images/system/192229.jpg",biography:null,institutionString:"University of São Paulo",institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"256851",title:"Prof.",name:"Ayşe",middleName:null,surname:"Gülşen",slug:"ayse-gulsen",fullName:"Ayşe Gülşen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256851/images/9696_n.jpg",biography:"Dr. Ayşe Gülşen graduated in 1990 from Faculty of Dentistry, University of Ankara and did a postgraduate program at University of Gazi. \nShe worked as an observer and research assistant in Craniofacial Surgery Departments in New York, Providence Hospital in Michigan and Chang Gung Memorial Hospital in Taiwan. \nShe works as Craniofacial Orthodontist in Department of Aesthetic, Plastic and Reconstructive Surgery, Faculty of Medicine, University of Gazi, Ankara Turkey since 2004.",institutionString:"Univeristy of Gazi",institution:null},{id:"255366",title:"Prof.",name:"Tosun",middleName:null,surname:"Tosun",slug:"tosun-tosun",fullName:"Tosun Tosun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255366/images/7347_n.jpg",biography:"Graduated at the Faculty of Dentistry, University of Istanbul, Turkey in 1989;\nVisitor Assistant at the University of Padua, Italy and Branemark Osseointegration Center of Treviso, Italy between 1993-94;\nPhD thesis on oral implantology in University of Istanbul and was awarded the academic title “Dr.med.dent.”, 1997;\nHe was awarded the academic title “Doç.Dr.” (Associated Professor) in 2003;\nProficiency in Botulinum Toxin Applications, Reading-UK in 2009;\nMastership, RWTH Certificate in Laser Therapy in Dentistry, AALZ-Aachen University, Germany 2009-11;\nMaster of Science (MSc) in Laser Dentistry, University of Genoa, Italy 2013-14.\n\nDr.Tosun worked as Research Assistant in the Department of Oral Implantology, Faculty of Dentistry, University of Istanbul between 1990-2002. \nHe worked part-time as Consultant surgeon in Harvard Medical International Hospitals and John Hopkins Medicine, Istanbul between years 2007-09.\u2028He was contract Professor in the Department of Surgical and Diagnostic Sciences (DI.S.C.), Medical School, University of Genova, Italy between years 2011-16. \nSince 2015 he is visiting Professor at Medical School, University of Plovdiv, Bulgaria. \nCurrently he is Associated Prof.Dr. at the Dental School, Oral Surgery Dept., Istanbul Aydin University and since 2003 he works in his own private clinic in Istanbul, Turkey.\u2028\nDr.Tosun is reviewer in journal ‘Laser in Medical Sciences’, reviewer in journal ‘Folia Medica\\', a Fellow of the International Team for Implantology, Clinical Lecturer of DGZI German Association of Oral Implantology, Expert Lecturer of Laser&Health Academy, Country Representative of World Federation for Laser Dentistry, member of European Federation of Periodontology, member of Academy of Laser Dentistry. Dr.Tosun presents papers in international and national congresses and has scientific publications in international and national journals. He speaks english, spanish, italian and french.",institutionString:null,institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",biography:"Zühre Akarslan was born in 1977 in Cyprus. She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"256417",title:"Associate Prof.",name:"Sanaz",middleName:null,surname:"Sadry",slug:"sanaz-sadry",fullName:"Sanaz Sadry",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256417/images/8106_n.jpg",biography:null,institutionString:null,institution:null},{id:"272237",title:"Dr.",name:"Pinar",middleName:"Kiymet",surname:"Karataban",slug:"pinar-karataban",fullName:"Pinar Karataban",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/272237/images/8911_n.png",biography:"Assist.Prof.Dr.Pınar Kıymet Karataban, DDS PhD \n\nDr.Pınar Kıymet Karataban was born in Istanbul in 1975. After her graduation from Marmara University Faculty of Dentistry in 1998 she started her PhD in Paediatric Dentistry focused on children with special needs; mainly children with Cerebral Palsy. She finished her pHD thesis entitled \\'Investigation of occlusion via cast analysis and evaluation of dental caries prevalance, periodontal status and muscle dysfunctions in children with cerebral palsy” in 2008. She got her Assist. Proffessor degree in Istanbul Aydın University Paediatric Dentistry Department in 2015-2018. ın 2019 she started her new career in Bahcesehir University, Istanbul as Head of Department of Pediatric Dentistry. In 2020 she was accepted to BAU International University, Batumi as Professor of Pediatric Dentistry. She’s a lecturer in the same university meanwhile working part-time in private practice in Ege Dental Studio (https://www.egedisklinigi.com/) a multidisciplinary dental clinic in Istanbul. Her main interests are paleodontology, ancient and contemporary dentistry, oral microbiology, cerebral palsy and special care dentistry. She has national and international publications, scientific reports and is a member of IAPO (International Association for Paleodontology), IADH (International Association of Disability and Oral Health) and EAPD (European Association of Pediatric Dentistry).",institutionString:null,institution:null},{id:"202198",title:"Dr.",name:"Buket",middleName:null,surname:"Aybar",slug:"buket-aybar",fullName:"Buket Aybar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202198/images/6955_n.jpg",biography:"Buket Aybar, DDS, PhD, was born in 1971. She graduated from Istanbul University, Faculty of Dentistry, in 1992 and completed her PhD degree on Oral and Maxillofacial Surgery in Istanbul University in 1997.\nDr. Aybar is currently a full-time professor in Istanbul University, Faculty of Dentistry Department of Oral and Maxillofacial Surgery. She has teaching responsibilities in graduate and postgraduate programs. Her clinical practice includes mainly dentoalveolar surgery.\nHer topics of interest are biomaterials science and cell culture studies. She has many articles in international and national scientific journals and chapters in books; she also has participated in several scientific projects supported by Istanbul University Research fund.",institutionString:null,institution:null},{id:"260116",title:"Dr.",name:"Mehmet",middleName:null,surname:"Yaltirik",slug:"mehmet-yaltirik",fullName:"Mehmet Yaltirik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/260116/images/7413_n.jpg",biography:"Birth Date 25.09.1965\r\nBirth Place Adana- Turkey\r\nSex Male\r\nMarrial Status Bachelor\r\nDriving License Acquired\r\nMother Tongue Turkish\r\n\r\nAddress:\r\nWork:University of Istanbul,Faculty of Dentistry, Department of Oral Surgery and Oral Medicine 34093 Capa,Istanbul- TURKIYE",institutionString:null,institution:null},{id:"172009",title:"Dr.",name:"Fatma Deniz",middleName:null,surname:"Uzuner",slug:"fatma-deniz-uzuner",fullName:"Fatma Deniz Uzuner",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/172009/images/7122_n.jpg",biography:"Dr. Deniz Uzuner was born in 1969 in Kocaeli-TURKEY. After graduating from TED Ankara College in 1986, she attended the Hacettepe University, Faculty of Dentistry in Ankara. \nIn 1993 she attended the Gazi University, Faculty of Dentistry, Department of Orthodontics for her PhD education. After finishing the PhD education, she worked as orthodontist in Ankara Dental Hospital under the Turkish Government, Ministry of Health and in a special Orthodontic Clinic till 2011. Between 2011 and 2016, Dr. Deniz Uzuner worked as a specialist in the Department of Orthodontics, Faculty of Dentistry, Gazi University in Ankara/Turkey. In 2016, she was appointed associate professor. Dr. Deniz Uzuner has authored 23 Journal Papers, 3 Book Chapters and has had 39 oral/poster presentations. She is a member of the Turkish Orthodontic Society. Her knowledge of English is at an advanced level.",institutionString:null,institution:null},{id:"332914",title:"Dr.",name:"Muhammad Saad",middleName:null,surname:"Shaikh",slug:"muhammad-saad-shaikh",fullName:"Muhammad Saad Shaikh",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Jinnah Sindh Medical University",country:{name:"Pakistan"}}},{id:"315775",title:"Dr.",name:"Feng",middleName:null,surname:"Luo",slug:"feng-luo",fullName:"Feng Luo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sichuan University",country:{name:"China"}}},{id:"423519",title:"Dr.",name:"Sizakele",middleName:null,surname:"Ngwenya",slug:"sizakele-ngwenya",fullName:"Sizakele Ngwenya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419270",title:"Dr.",name:"Ann",middleName:null,surname:"Chianchitlert",slug:"ann-chianchitlert",fullName:"Ann Chianchitlert",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419271",title:"Dr.",name:"Diane",middleName:null,surname:"Selvido",slug:"diane-selvido",fullName:"Diane Selvido",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419272",title:"Dr.",name:"Irin",middleName:null,surname:"Sirisoontorn",slug:"irin-sirisoontorn",fullName:"Irin Sirisoontorn",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"355660",title:"Dr.",name:"Anitha",middleName:null,surname:"Mani",slug:"anitha-mani",fullName:"Anitha Mani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"355612",title:"Dr.",name:"Janani",middleName:null,surname:"Karthikeyan",slug:"janani-karthikeyan",fullName:"Janani Karthikeyan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"334400",title:"Dr.",name:"Suvetha",middleName:null,surname:"Siva",slug:"suvetha-siva",fullName:"Suvetha Siva",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}}]}},subseries:{item:{id:"26",type:"subseries",title:"Machine Learning and Data Mining",keywords:"Intelligent Systems, Machine Learning, Data Science, Data Mining, Artificial Intelligence",scope:"The scope of machine learning and data mining is immense and is growing every day. It has become a massive part of our daily lives, making predictions based on experience, making this a fascinating area that solves problems that otherwise would not be possible or easy to solve. This topic aims to encompass algorithms that learn from experience (supervised and unsupervised), improve their performance over time and enable machines to make data-driven decisions. It is not limited to any particular applications, but contributions are encouraged from all disciplines.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/26.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11422,editor:{id:"24555",title:"Dr.",name:"Marco Antonio",middleName:null,surname:"Aceves Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves Fernandez",profilePictureURL:"https://mts.intechopen.com/storage/users/24555/images/system/24555.jpg",biography:"Dr. Marco Antonio Aceves Fernandez obtained his B.Sc. (Eng.) in Telematics from the Universidad de Colima, Mexico. He obtained both his M.Sc. and Ph.D. from the University of Liverpool, England, in the field of Intelligent Systems. He is a full professor at the Universidad Autonoma de Queretaro, Mexico, and a member of the National System of Researchers (SNI) since 2009. Dr. Aceves Fernandez has published more than 80 research papers as well as a number of book chapters and congress papers. He has contributed in more than 20 funded research projects, both academic and industrial, in the area of artificial intelligence, ranging from environmental, biomedical, automotive, aviation, consumer, and robotics to other applications. He is also a honorary president at the National Association of Embedded Systems (AMESE), a senior member of the IEEE, and a board member of many institutions. His research interests include intelligent and embedded systems.",institutionString:"Universidad Autonoma de Queretaro",institution:{name:"Autonomous University of Queretaro",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,series:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403"},editorialBoard:[{id:"43680",title:"Prof.",name:"Ciza",middleName:null,surname:"Thomas",slug:"ciza-thomas",fullName:"Ciza Thomas",profilePictureURL:"https://mts.intechopen.com/storage/users/43680/images/system/43680.jpeg",institutionString:null,institution:{name:"Government of Kerala",institutionURL:null,country:{name:"India"}}},{id:"16614",title:"Prof.",name:"Juan Ignacio",middleName:null,surname:"Guerrero Alonso",slug:"juan-ignacio-guerrero-alonso",fullName:"Juan Ignacio Guerrero Alonso",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6HB8QAM/Profile_Picture_1627901127555",institutionString:null,institution:{name:"University of Seville",institutionURL:null,country:{name:"Spain"}}},{id:"3095",title:"Prof.",name:"Kenji",middleName:null,surname:"Suzuki",slug:"kenji-suzuki",fullName:"Kenji Suzuki",profilePictureURL:"https://mts.intechopen.com/storage/users/3095/images/1592_n.jpg",institutionString:null,institution:{name:"University of Chicago",institutionURL:null,country:{name:"United States of America"}}},{id:"214067",title:"Dr.",name:"W. David",middleName:null,surname:"Pan",slug:"w.-david-pan",fullName:"W. David Pan",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSEI9QAO/Profile_Picture_1623656213532",institutionString:null,institution:{name:"University of Alabama in Huntsville",institutionURL:null,country:{name:"United States of America"}}},{id:"72920",title:"Prof.",name:"Yves",middleName:"Philippe",surname:"Rybarczyk",slug:"yves-rybarczyk",fullName:"Yves Rybarczyk",profilePictureURL:"https://mts.intechopen.com/storage/users/72920/images/system/72920.jpeg",institutionString:"Dalarna University, Faculty of Data and Information Sciences",institution:{name:"Dalarna University",institutionURL:null,country:{name:"Sweden"}}}]},onlineFirstChapters:{paginationCount:10,paginationItems:[{id:"82196",title:"Multi-Features Assisted Age Invariant Face Recognition and Retrieval Using CNN with Scale Invariant Heat Kernel Signature",doi:"10.5772/intechopen.104944",signatures:"Kamarajugadda Kishore Kumar and Movva Pavani",slug:"multi-features-assisted-age-invariant-face-recognition-and-retrieval-using-cnn-with-scale-invariant-",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Pattern Recognition - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11442.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"82063",title:"Evaluating Similarities and Differences between Machine Learning and Traditional Statistical Modeling in Healthcare Analytics",doi:"10.5772/intechopen.105116",signatures:"Michele Bennett, Ewa J. Kleczyk, Karin Hayes and Rajesh Mehta",slug:"evaluating-similarities-and-differences-between-machine-learning-and-traditional-statistical-modelin",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Machine Learning and Data Mining - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11422.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"81791",title:"Self-Supervised Contrastive Representation Learning in Computer Vision",doi:"10.5772/intechopen.104785",signatures:"Yalin Bastanlar and Semih Orhan",slug:"self-supervised-contrastive-representation-learning-in-computer-vision",totalDownloads:30,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Pattern Recognition - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11442.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"79345",title:"Application of Jump Diffusion Models in Insurance Claim Estimation",doi:"10.5772/intechopen.99853",signatures:"Leonard Mushunje, Chiedza Elvina Mashiri, Edina Chandiwana and Maxwell Mashasha",slug:"application-of-jump-diffusion-models-in-insurance-claim-estimation-1",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"81471",title:"Semantic Map: Bringing Together Groups and Discourses",doi:"10.5772/intechopen.103818",signatures:"Theodore Chadjipadelis and Georgia Panagiotidou",slug:"semantic-map-bringing-together-groups-and-discourses",totalDownloads:21,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"79491",title:"Fuzzy Perceptron Learning for Non-Linearly Separable Patterns",doi:"10.5772/intechopen.101312",signatures:"Raja Kishor Duggirala",slug:"fuzzy-perceptron-learning-for-non-linearly-separable-patterns",totalDownloads:17,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Raja Kishor",surname:"Duggirala"}],book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"81331",title:"Machine Learning Algorithm-Based Contraceptive Practice among Ever-Married Women in Bangladesh: A Hierarchical Machine Learning Classification Approach",doi:"10.5772/intechopen.103187",signatures:"Iqramul Haq, Md. Ismail Hossain, Md. Moshiur Rahman, Md. Injamul Haq Methun, Ashis Talukder, Md. Jakaria Habib and Md. Sanwar Hossain",slug:"machine-learning-algorithm-based-contraceptive-practice-among-ever-married-women-in-bangladesh-a-hie",totalDownloads:21,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Machine Learning and Data Mining - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11422.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"80937",title:"Assessing Heterogeneity of Two-Part Model via Bayesian Model-Based Clustering with Its Application to Cocaine Use Data",doi:"10.5772/intechopen.103089",signatures:"Ye-Mao Xia, Qi-Hang Zhu and Jian-Wei Gou",slug:"assessing-heterogeneity-of-two-part-model-via-bayesian-model-based-clustering-with-its-application-t",totalDownloads:24,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"78846",title:"Clustering Algorithms: An Exploratory Review",doi:"10.5772/intechopen.100376",signatures:"R.S.M. Lakshmi Patibandla and Veeranjaneyulu N",slug:"clustering-algorithms-an-exploratory-review",totalDownloads:146,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"78463",title:"Clustering by Similarity of Brazilian Legal Documents Using Natural Language Processing Approaches",doi:"10.5772/intechopen.99875",signatures:"Raphael Souza de Oliveira and Erick Giovani Sperandio Nascimento",slug:"clustering-by-similarity-of-brazilian-legal-documents-using-natural-language-processing-approaches",totalDownloads:157,totalCrossrefCites:1,totalDimensionsCites:1,authors:null,book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}}]},publishedBooks:{paginationCount:1,paginationItems:[{type:"book",id:"7437",title:"Nanomedicines",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7437.jpg",slug:"nanomedicines",publishedDate:"February 13th 2019",editedByType:"Edited by",bookSignature:"Muhammad Akhyar Farrukh",hash:"0e1f5f6258f074c533976c4f4d248568",volumeInSeries:5,fullTitle:"Nanomedicines",editors:[{id:"63182",title:"Dr.",name:"Muhammad Akhyar",middleName:null,surname:"Farrukh",slug:"muhammad-akhyar-farrukh",fullName:"Muhammad Akhyar Farrukh",profilePictureURL:"https://mts.intechopen.com/storage/users/63182/images/system/63182.png",institutionString:"Forman Christian College",institution:{name:"Forman Christian College",institutionURL:null,country:{name:"Pakistan"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.png",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}},{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}}]},submityourwork:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:319,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:133,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:16,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],subseriesList:[{id:"14",title:"Cell and Molecular Biology",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression"},{id:"15",title:"Chemical Biology",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors"},{id:"17",title:"Metabolism",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation"},{id:"18",title:"Proteomics",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"July 5th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:4,numberOfPublishedChapters:319,numberOfPublishedBooks:32,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"14",title:"Cell and Molecular Biology",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",annualVolume:11410,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",annualVolume:11411,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null,editorialBoard:[{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",fullName:"Abdulsamed Kükürt",profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",institutionString:null,institution:{name:"Kafkas University",institutionURL:null,country:{name:"Turkey"}}},{id:"241413",title:"Dr.",name:"Azhar",middleName:null,surname:"Rasul",fullName:"Azhar Rasul",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRT1oQAG/Profile_Picture_1635251978933",institutionString:null,institution:{name:"Government College University, Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"178316",title:"Ph.D.",name:"Sergey",middleName:null,surname:"Sedykh",fullName:"Sergey Sedykh",profilePictureURL:"https://mts.intechopen.com/storage/users/178316/images/system/178316.jfif",institutionString:null,institution:{name:"Novosibirsk State University",institutionURL:null,country:{name:"Russia"}}}]},{id:"17",title:"Metabolism",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",annualVolume:11413,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},{id:"18",title:"Proteomics",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://mts.intechopen.com/storage/users/81926/images/system/81926.png",institutionString:"Suez Canal University",institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/72147",hash:"",query:{},params:{id:"72147"},fullPath:"/chapters/72147",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()