GTA results.
\r\n\t
",isbn:"978-1-83881-111-2",printIsbn:"978-1-83880-992-8",pdfIsbn:"978-1-83881-112-9",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"acb2875b3bfc189c9881a9b44b6a5184",bookSignature:"Dr. Abdo Abou Jaoudé",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11865.jpg",keywords:"Linear Operators, Normal Operators, Spectral Theorem, Applications, Differential Operators, Integral Operators, Functional Calculus, Complex Variables, Complex Analysis, Theory, Recent Advances, Latest Trends",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 13th 2022",dateEndSecondStepPublish:"June 21st 2022",dateEndThirdStepPublish:"August 20th 2022",dateEndFourthStepPublish:"November 8th 2022",dateEndFifthStepPublish:"January 7th 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"2 months",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Abdo Abou Jaoudé is a pioneering Associate Professor of Mathematics and Statistics at Notre Dame University-Louaizé. 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This approach raises new and important issues related to the efficiency, reliability and safety of the PV systems, either autonomous or integrated in the electrical grid [1, 2].
\nIn the case of grid-connected PV systems, the occurrence of system failures may affect the operation of other interconnected systems, that is why a thorough reliability analysis of such systems should be carried out [3, 4, 5]. The reliability analysis also makes it possible to establish an acceptable maintenance plan for both the user and the system as efficiently as possible [6, 7]. However, a reliability analysis is often missing from the feasibility study of photovoltaic systems or is treated superficially due to an incomplete methodological approach or lack of specific simulation tools [8, 9]. A PV system for LED lighting applications has been analyzed [10, 11]. To overcome the reported inconveniences, it is envisaged the reliability analysis, using RAMS (Reliability, Availability, Maintainability, and Safety) statistical models through accelerated testing and application of stress levels [12, 13, 14, 15]. Starting from ground studies, the failures of PV systems have shown that manufacturers do not correctly perform reliability analysis of their PV modules’ lifetime. For this reason, a small part of the PV modules fails before the lifetime specified by the manufacturer [16]. Reliability analysis applies to both PV systems, and simple systems, such as LED-based lighting lamps [17].
\nThe authors proposed and carried out the reliability analysis of solar cells for specific meteorological conditions [16, 18, 20, 21]. To assess the reliability of the integrated PV system with LED lighting applications, its operating characteristics have been used for a time period [19], and in the case of the simple LED lighting system there were used thermal characteristics of the studied LED lamp [22, 23].
\nThe most relevant analyzes proposed by the authors in this paper are based on reliability block diagrams (RBDs) required for development of RAMS for studied PV systems. RBD diagrams have been developed for: (1) definition of PV systems, (2) description of interdependence between components, (3) identification of how they degrade/fail, and (4) appreciation of how the PV system reliability is influenced.
\nThe reliability of a product can be defined as the probability of performing its tasks without incidents within a specified time, under previously established conditions. On this basis, the quality of a product is determined, the reliability concept being applied in almost all areas of engineering, in the preventive maintenance of systems and their components. It is envisaged the modeling of the product’s lifetime, represented by the time it has worked successfully or its time until the moment of failure. For the purpose of accurately determining the lifetime, it has been proposed an accelerate product testing (qualitatively or quantitatively during its lifetime) [25, 29].
\nQualitative accelerated testing only provides information about system malfunctions or ways of failure. Qualitative tests do not quantify the system’s life (or reliability) characteristics under normal conditions of utilization, but provide valuable information on the type and level of demands to use during a later quantitative test. In qualitative accelerated testing, the expected result consists in identifying deficiencies and ways of failure without predicting the life of the product under normal conditions of utilization [2, 24, 26].
\nAccelerated quantitative testing involves the estimation of product lifetime characteristics, obtained under normal conditions of utilization after an accelerated test. High accelerated life test (HALT) provides various information about the product and its failure mechanisms. Accelerated quantitative testing consists of tests designed to quantify the life characteristics of a product, component or system under normal conditions of utilization, and to provide information on determining the reliability of the system (probability of system failure under various conditions, life expectancy, average lifetime). It can be used to carry out risk assessments or for comparison of different design methods [9].
\nTwo acceleration methods were designed [9] for use of: (1) acceleration rate and (2) stress acceleration, in order to obtain time data on product failure at an accelerated rate. For products where use of acceleration rate is impractical, a second method can be applied, in which the normal stress level of a product is exceeded.
\nThe reliability of photovoltaic systems and their components/elements (solar cells, PV modules, electrical storage systems, inverters, regulators, etc.) are the key issues in manufacturing performance and financially competitive photovoltaic installations. For this purpose, a number of methods for testing and improving the reliability of PV products have been studied [13, 15], such as: (1) the accelerated test method for solar cells [27]; (2) analysis of defect detection and degradation mechanisms detection for solar cells [14], as well as PV systems and their components [28]; (3) energy production forecasting based on the rate of failure and degradation of PV systems and their applications [12].
\nIn this paper the authors proposed to integrate some of these methods by using a specialized complex simulation platform, namely SYNTHESIS, which allows a physical and statistical approach for PV products; it is envisaged the development of a highly useful RAMS methodology, both in research and in the efficient design of PV systems and their applications [29, 30, 31].
\nIn order to perform a fairly accurate reliability analysis of the PV systems and their components, the authors of this paper have chosen to use the SYNTHESIS simulation platform developed by
The
The
The
The
The
The studied integrated PV system is defined as a PV application, which uses a consumer for a specific application (see Figure 1). The implementation of the RAMS analysis of the PV system was performed using the modeling and simulation SYNTHESIS platform for system reliability [32]. When it is analyzed the reliability of studied solar cells, the simulation module used in the SYNTHESIS platform was Weibull/ALTA. This module statistically addresses reliability issues through statistical repartitions and together with the ALTA module contributes to the accelerated life tests. For the analysis of the PV system studied in the paper, the BlockSim simulation module was used within the same platform. The simulation of the PV systems is based on the RBD diagram, as well as on the component types and the way they are arranged in the system.
\nPV integrated system concept.
For a rigorous understanding of the RAMS analysis for the PV integrated system, it was analyzed the highlighting of solar cell degradation. By performing a statistical analysis based on the Weibull, Exponential and Normal repartitions, it was possible to estimate the most frequent events (characterized by main meteorological parameters: solar irradiance, temperature and humidity) that contribute to the most probable degradation of solar cells during their lifetime. The statistical approach was correlated with the accelerating lifetime method by stressing solar cells using different meteorological parameters (Figure 2). The present study considered only the three meteorological parameters mentioned above, which have an essential role in cell degradation.
\nAccelerated stress test diagram.
Reliability analysis of solar cells has been developed based on the accelerated testing method, which has certain advantages: (1) avoiding testing in real and more severe conditions that can lead to cell degradation/failure, (2) determining the frequent reasons that determine cell failure. Highly accelerated stress screening (HASS) aimed at identifying defects in as short time as possible compared to the standard method (based on cell monitoring and results analysis), which may take several months/years. Accelerated testing (HASS) can be performed with either a weather parameter (e.g., temperature/solar irradiance) or combined with few weather parameters (such as, temperature, humidity and solar irradiance). Within this paper the HASS analysis was implemented in the version of the three key meteorological parameters.
\nThe authors’ study also looked at establishing the best statistical reparation used to make the most accurate predictions of the of solar cells life time. Three types of statistical repartitions, namely Weibull, Exponential and Normal, were evaluated using the SYNTHESIS software, and based on the correlation cause (determined by one of the three main meteorological parameters)—occurrence (characterized by the degradation degree of the solar cell) it was possible to obtain the probabilities for the three repartitions (the black curve defines the Weibull repartition, the green one defines the normal repartition, and the purple one defines the exponential repartition), using the HASS test. In Figure 3a the curves of the mentioned statistical repartitions were obtained. It can be seen that Weibull repartition is the closest to the values of the three main meteorological parameters. The accelerated test has highlighted that the most influential meteorological parameter in solar cell degradation (characterized by most occurrences) is temperature, followed by humidity and further by solar irradiance. Figure 3b shows the temporal evolution (in hours) of the degradation level of solar cells for two operating modes: under stress conditions (purple continuous curve) and in standard conditions (blue continuous curve).
\n(a) The life distribution of solar cells for three distribution functions, (b) degradation level of solar cells simulation in two modes: standard conditions and stress conditions.
Under standard operating conditions, a major degradation level (about 70%) is achieved over a time interval of 2500 h, while under stress conditions the same level of degradation of 70% is achieved over a time interval of 1600 h (see Figure 3b).
\nUsing the stress results of the HASS test (purple curve in Figure 3b), it was possible to determine by numerical simulation in the SYNTHESIS platform, the limit value of the cell operating time in normal conditions, respectively 1600 h, according to the curve in Figure 4a. The accelerated test also enabled the probable number of solar cell failures (see Figure 4b) within the range of 1000–2800 h, with a higher concentration between 1500 and 2800 h according to the results from Figure 4a; the linear dependence defines the expected failures curve based on Weibull repartition.
\n(a) Baseline survival of solar cells module simulation in stress conditions, (b) cumulative number of failures as function of time.
The analyzed PV system consists of a set of components, arranged to achieve the established performance and to provide acceptable reliability. The reliability characteristics of the PV system and its components can be presented in RBD-type diagrams illustrating their possible failures. These failures are due to a facile analysis of the failures risk.
\nThe RAMS analysis for the photovoltaic system aimed to determine how the system and its components worked over a 5000-h period (about 7 months). For this purpose, it was analyzed the time evolution of the PV generator efficiency, as well as of the PV system’s battery efficiency. There were noted high fluctuations for the efficiency of PV generator, slower fluctuations in battery efficiency based on fuzzy logic controller (FLC) and maximum power point tracking (MPPT) methods (see Figure 5). The specific application (electric consumer) will be discussed further in Section 3.5.
\nEfficiency and functionality of a PV system for its main three components: (1) PV generator, (2) battery and (3) electrical load.
Using the results obtained in Figure 6a we could establish the availability diagram of the PV system giving the operation time and unavailability periods (when the PV system is not working). The unavailability periods are usually small; after 3000 h of operation there is a 500-h period when the PV system has to be repaired due to different failures. In Figure 6a there are also analyzed the main components of the PV system (PV modules, battery and load) to be maintained. The complex analysis of defect risks and preventive planned maintenance of the components aims at avoiding spontaneous malfunctions and premature degradation of the PV system.
\n(a) PV system availability/unavailability diagram, (b) degradation of system components based on availability/unavailability diagram.
In Figure 6b the level of degradation for each component of the PV system is presented. Although, excepting the inverter, all other components exceed the critical threshold to the end of the test (3500–4500 hours); however, two components, respectively the PV modules and the storage system, are the most vulnerable to failure (exceeding the critical level much earlier). The simulation tools allowed to obtain the efficiency degradation analysis of the PV system (see Figure 7a). A good PV system is characterized by small fluctuations of the time evolution of efficiency, determining a usual degradation based on normal operation requirements for the analyzed simulation period (5000 hours).
\n(a) Time degradation of PV system efficiency, (b) statistical unreliability of the PV system in time.
The probability of non-functioning of the PV system over time is sensitive after 2000 hours of the product use (see Figure 7b). It is noted the role played by this diagram in RAMS analysis; when the components of the PV system start to degrade, the number of failures increases, that leads to the need for more frequent interventions (repairs) on the PV system.
\nThe RAMS approach, based on the SYNTHESIS simulation platform, was able to obtain preliminary information on the time behavior of the PV system and its components (from the point of view of its reliability and maintenance) which could be very useful for its proper design.
\nA PV system based on specific application has been studied. Analysis of the PV integrated system was possible using the availability/unavailability diagram of its components (Figure 8). This diagram describes the interdependence between the components and defines how the system works. An important parameter of the availability/unavailability diagram is the power load of specific application that is influenced by the operating mode (using either serial, parallel or mixed type configurations). Each component of the PV system is characterized by a repairable block, parameterized in the BlockSim simulation module.
\nDiagram of the availability/unavailability (up/down) of the PV integrated system.
A feature of the up/down diagram is the planning of the PV system maintenance; thus, as a result of prompt interventions in order to repair its components, spontaneous or irreversible failures are eliminated, the system thus becoming functional over the entire lifetime.
\nThe failure rate for each component of the PV system was also being studied. The highest failure rate is presented, by the PV modules, according to the results in Figure 9. This is due to the specific configurations for these components (series, parallel or mixed) that increase their failure rate compared with other components (battery, inverter, regulator, etc.).
\nTime evolution (in hours) of components failure rate of the PV system depending on operating life cycle.
The authors have proposed the reliability analysis of a PV system for a specific application using a performance SYNTHESIS simulation platform, which allowed the system to function more accurately by identifying probable defects in certain components of the system.
\nThis contribution is based on an original approach of RAMS reliability analysis. It was considered the adaptation of up/down reliability block diagrams (RBD) from
The main results obtained by the authors in this article could be synthesized as follows:
The simulation of the solar cells operation on an accelerated test basis (under the influence of three essential meteorological parameters: solar irradiance, temperature and humidity) allowed to put in evidence the normal operating time under normal/stress conditions, defining the initial degradation time of stressed solar cell (determined by a possible degradation of the cell’s I-V characteristics). The Weibull most probable statistical repartition has also been identified using a proper solar cells testing; on this basis, the operating duration in which a significant concentration of defects is achieved, was determined.
The simulation of the PV system operation allowed to obtain information on the availability/unavailability of the system, based on a RBD diagram. Using this diagram, PV components that may exhibit a higher rate of degradation (PV modules, electrical battery) during operation are identified. Also, useful information on degradation of the PV system was obtained (based on the efficiency degradation curve and the non-functional curve).
The results obtained by the authors were partially validated by other authors research studies, regarding the availability and degradation of analyzed systems [34, 35].
\nIn order to increase the reliability of the PV system and its components, it is necessary to develop an elaborated failure management strategy that involves knowing the initial level of reliability and developing efficient solutions for planning and assessing the probable risks of failure. The essential directions for such a strategy could be as follows:
experimental accelerated testing of the PV system under the influence of possible degradation factors;
identifying the cause of failure in experimental conditions, that is intended to isolate possible failures occurring in the PV system;
implementing effective corrective actions to significantly reduce the failures of the PV system.
The authors are grateful for the financial support of Ministry of Research and Innovation, Romanian Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI), no. 34/2016 contract, SOLHET project “High-performance tandem hetero-junction solar cells for specific applications.”
\nSince 2020, we have faced drastic changes in our lives due to the pandemic. This caused a big paradigm shift in working styles. Parallel careers or multiple jobs are getting more common, and people are ascertaining their own competencies. The utilization of personal knowledge will continue to accelerate and this study sheds light on its societal value.
Aoki [1] revealed that participation in knowledge sharing has a significant positive impact on contributors’ well-being. Those findings are more pertinent as utilization of personal knowledge increases under the ongoing paradigm shift in work style, and the expansion of C-to-C business. However, the reason for the correlation between knowledge sharing and well-being has not been identified. This research aims to reveal the relationship between knowledge sharing and well-being.
Due to the growing sharing economy and the large ongoing paradigm shift in work styles caused by the pandemic, people have more opportunities to utilize their personal knowledge than ever before. However, vast amounts of personal knowledge are untapped. For instance, one instantiation of personal knowledge is user innovation, and user innovation research has pointed out the ‘market failure’ in its diffusion due to a lack of incentives for the innovators [2, 3]. This study contributes to increase knowledge sharing and filling the gap between personal knowledge and society.
Since von Hippel [4] pointed out that not only manufacturers but also ‘users’ innovate, user innovation has been studied by various researchers throughout the world. In early research, the term ‘users’ referred to firms that were supplied products by manufacturers; in other words, user innovation was carried out in the business-to-business community. Over the decades, the importance of individual consumers as user innovators has been articulated (e.g. [5]). In this digital era, the line between a firm and a consumer is becoming blurred, and co-creation between the two has become pervasive.
Some users innovate by themselves and whose innovations occasionally have been commercially successful. Previous studies showed that user innovations increased social welfare because user innovators created financial value from their leisure-time activities [6, 7]. Furthermore, user innovation is distinct from producer innovation in that the former provides benefits from participation, including the use or sale of the output to the innovators themselves [6, 8]. Consequently, user innovation which brings satisfaction to the innovators increases social welfare better than producer innovation.
Even if it has a high potential to enhance social welfare, user innovation tends to be restricted to innovators themselves and not diffused. User innovators are likely to choose free information diffusion, rather than paid diffusion, and avoid seeking commercialization on their own or through an existing firm, because it costs more than they would gain. Earlier studies have shown ‘market failure’ in user innovation diffusion [2, 3]. When valuable innovation remains underground, it is society’s loss.
Each user innovation is based on personal needs, which, by nature, are self-centered. Thus, innovation communities play an important role in integrating these isolated individuals [5]. Baldwin et al. [9] revealed that user innovators who commercialized their innovations had participated in innovation communities at an earlier stage and improved their ideas. Earlier research has shown that user communities play an important role in diffusing user innovations and has examined the innovators’ motivations to participate in these communities.
People tend to join peer communities (e.g., open-source software communities) to fulfill personal needs. Then, their participation becomes a hobby, and they discover that they are helping other people [10]. In addition to personal needs, feedback from peers and enjoyment were found to be important motivations [11, 12, 13, 14]. Feedback in the user community also plays a key role in increasing entrepreneurship [10, 15].
Diffusion of user innovation is ultimate knowledge sharing and contributors enjoy financial and/or non-financial benefits from sharing. Aoki [1] focused on non-financial benefits and revealed that knowledge sharing increases contributors’ well-being.
In terms of psychology, Seligman [16] defined well-being as the ultimate objective of positive psychology. He argued that well-being is sustainable and separate from ‘happiness’ and suggested the importance of flourishing as a standard to measure well-being. Flourishing consists of five elements, positive emotion, engagement, relationship, meaning, accomplishment, or PERMA for short [16]. Each element represents the following.
Positive emotion: a subjective feeling of well-being itself
Engagement: a subjective feeling denoting the extent to which people are absorbed in something
Relationships with others
Meaning: the extent how lives are meaningful for themselves
Accomplishment, the extent how people accomplish something in their lives
Aoki [1] visualized non-financial benefits from knowledge sharing with the measurement of PERMA which was developed by Butler and Kern [17] and have been used to explain the relationship between well-being and a continuous process such as career [18], education [19, 20], and hobby [21]. Although this is an important finding, the cause has not yet been revealed. Thus, this research explores why knowledge sharing increases well-being. In line with Aoki [1], this research follows Seligman’s definition of well-being and adopts PERMA to examine the changes in well-being that knowledge sharing contributors’ experience.
To answer the research question, in-depth interviews with the knowledge-sharing contributors were conducted. The interviewees were sourced from LEGO users who share their original creations. The LEGO Group, one of the world’s largest toy manufacturers, was founded in 1932. The brick in its present form was launched in 1958 and has attracted people for over 60 years. LEGO has a lot of adult fans across the world who call themselves AFOL (Adult Fan of LEGO). The LEGO Group has collaborated with these users with novel ideas for decades and much research has revealed the competitive advantages of this collaboration (e.g. [22, 23, 24, 25, 26]). Antorini, Muñiz and Askildsen [11] pointed out that the relationship among community members is the strongest motivation for contributors to co-creation with LEGO.
Co-creation among LEGO and its users varies from new product development to programming. Furthermore, users frequently share ideas, some of which are quite new beyond the brand’s intention. This research examines how such knowledge sharing affects contributors themselves. This research distinguishes itself from previous research mainly in two aspects. First, this research observes changes in contributors not one specific point but over time. Second, this research shed light to not firms but contributors.
The interview respondents were selected using the following criteria: who share the idea related to LEGO with other people in some form. The interviews reached theoretical saturation with ten respondents. The primary respondent activity was sorted into three groups as follows.
Artistic photography of LEGO in scenic environments (n = 4).
Designing and creating original crafts with LEGO blocks (n = 4).
Programming original LEGO Mindstorms crafts (n = 2).
Their activities were user-generated beyond the firm’s original aim. Group A especially, as they go out of their homes with LEGO blocks and/or mini-figures, and enjoy sharing with other people through SNS. These activities were not expected by the firm; however, they have become worldwide trends among LEGO users.
The one-to-one semi-structured interviews covered the beginning of LEGO, current occasion to use, purchase situations, and the relationship with the user community and the firm. The interviews were conducted between September 2020 and February 2021, and each interview lasted 30–120 min (average 59 min).
To structurally understand chronological changes in the respondents, the data were analyzed using the Grounded theory approach (GTA) [27]. In line with other marketing research (e.g., [28, 29, 30]), this chapter follows the Strauss approach (e.g. [31]). All interviews were transcribed and applied the scheme of open, axial coding converging into theory as follows [32]:
breaking down data into manageable analytic pieces.
brainstorming with data to arrive at possible meanings and delineate the concepts (open coding).
elaborating concepts to form categories (axial coding).
integrating categories into a core category and other categories.
analyzing data for context.
The data were analyzed (first and second steps) after each interview, and data collecting and analysis were continued until reaching theoretical saturation. The concepts in open coding were based on the actual language respondents used. Then, the concepts were grouped into categories based on theoretical abstracts in axial coding. For analyst triangulation, the coding results were reviewed by the marketing researcher and two of the interview respondents; and the theory was constructed objectively via the reviewers’ feedback. Finally, the categories were referred to PERMA [16] to observe the relationship between knowledge sharing and well-being.
Through the process of coding, 22 first-order categories were distilled from 67 concepts and consequently converged into the seven second-order categories ending with the two core categories below (Table 1). The results are described below for each second-order category.
First-order categories | Seligman [16] | Second-order categories | |
---|---|---|---|
1 | Childhood experiences | A) Formative LEGO experience | |
2 | Superiority of LEGO blocks | Positive emotion | |
3 | Restart using LEGO | Positive emotion | B) Renewed LEGO experience |
4 | Exposed to new playing styles via the internet | Positive emotion | |
7 | Absorbed in creating | Engagement | C) Absorption in LEGO |
8 | Being an extension of oneself | Engagement | |
9 | Huge expenditure | ||
5 | Self-recognition of developing creativity | Engagement | D) Satisfaction of intellectual curiosities |
6 | Knowledge transformation | Meaning | |
10 | Goal representative of ideals | Meaning | E) Goal setting and hardships to reach the achievement |
11 | Hurdles to reach achievement | ||
12 | Collaboration with peers | Relationship | F) Deepening of knowledge and experiences via competitive co-creation (core category) |
13 | Deep communication | Relationship | |
14 | Opportunities for feedback | Accomplishment | |
15 | Existence of more experienced people | ||
16 | Objective judgment of one’s own works | Meaning | |
17 | Recognition from third parties | Accomplishment | |
18 | Collaborative relations with LEGO | Relationship | |
19 | Interests and comprehension of brand mission | Meaning | |
20 | Social engagement via LEGO | Meaning | G) Passing on knowledge and experience to the next generation (core category) |
21 | Awareness of salient issues | Meaning | |
22 | Altruism | Meaning |
GTA results.
They found themselves spending a lot of time and money as the product lines fired up their enthusiasm for collecting.
Moreover, the restrictive regulations of colors and shapes promoted their creativity. The author found that AFOLs usually purchase sets to collect parts necessary for their creations. In other words, they do not follow the official instructions but made original creations using blocks collected from various sources. Furthermore, each respondent is a specialist in a field of their LEGO creations, for example, graphic design or photography. Their LEGO creations inspired them with their specialties, and they recognized this synergy.
Though they aim to entertain others in addition to their own enjoyment, they face some hardships. First, realizing their ideas is not only fun but quite challenging. Furthermore, all respondents mentioned the high cost of LEGO. Some respondents do not purchase official sets, but individual authentic blocks from overseas through unofficial channels, which needs know-how.
Experiencing success in contests or recognizing well-known people in their community enthused the respondents to further create.
Importantly, the LEGO group assists those collaborative relationships. The firm officially recognizes such user communities worldwide as LEGO User Group (LUG). While LUGs contribute to diffusing LEGO, the firm supports its activities. Some respondents belong to LUGs and have indirect collaborative relationships with the firm, whereas some are more directly related to the firm such as by collaborating in new product development.
In summary, AFOLs compete with each other in creating, and such competition increases their motivation. Thus their relationships are co-creative overall. The balance between competition and co-creation enriches the respondents’ knowledge and experiences. Furthermore, it broadens their opportunities beyond LEGO creations.
As a hobby or as a source of income, the respondents commonly expanded their fields through LEGO activities and expanded their connection to society.
Moreover, some respondents eagerly passed on their experiences, which was deeply satisfying. Particularly, they were passionate about developing children’s creativities and tried to do so by holding events, establishing websites, and so on.
Referring to their beliefs, they tended to be unsatisfied with current product lines and contemporary trends in society which spoils children’s creativity.
The author finally matched the first-order categories to the PERMA model [16], where appropriate, to observe undergoing changes in the respondents (Table 1). The respondents started their experience with a ‘positive emotion,’ such as fun, then fell into absorption (‘engagement’). Then, they recognized the meaning of investing their cultivated knowledge into their creations and their ideals (‘meaning’). In the process of achieving their goals, they shared their knowledge with their peers (‘relationship’) and felt a sense of ‘accomplishment’ via competition and recognition. Finally, most were motivated to be altruistic (higher level of ‘meaning’) in the form of knowledge flow to the next generation. Four of the categories do not match PERMA elements but influenced the PERMA outcome. For example, experience in childhood includes unsatisfied feelings but it increases the respondents’ absorption in adulthood.
As a result, it was proven that the flow of knowledge sharing is circular while increasing contributors well-being (Figure 1). The respondents had accumulated knowledge and experience with LEGO since their childhood (A). They then found a renewed attraction to LEGO and became reabsorbed in it in their adulthood (B&C). They enjoyed applying their non-LEGO knowledge to their LEGO creations and realizing that it was developing their creativity (D). Sooner after, they each set their own goal which represented their ideal, but there were obstacles (E). To overcome those obstacles, they developed their skills and ideas by collaborating with other users, sometimes competing with them, which resulted in a deepening of their knowledge and experience (F). After reaching their achievements, most respondents were motivated to pass on their experiences to the next generation.
The flow of knowledge sharing.
This study concludes that the reason for knowledge sharing increases contributors well-being is that it further deepens their knowledge and experience. The respondents could further deepen their previously accumulated knowledge and experience with LEGO creation through competitive co-creation with others. Moreover, regardless of their initial goals, they converged into the broader goal of knowledge flow to the next generation which, importantly, contributes to the realization of sustainability in knowledge development.
This study demonstrates the importance of competitive co-creation with individuals utilizing personal knowledge. This personal knowledge is not necessarily related to their work or major, but rather their outside interests which were accumulated over a longer span. A marriage of diversified ideas could be the resource for innovative ideas.
The COVID-19 pandemic has restricted the flow of people and goods, but owing to the internet, not knowledge. Activation of knowledge sharing increases people’s well-being and social welfare.
This work was supported by JSPS Grants-in-Aid for Scientific Research (Grant Number 20K13631).
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His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. 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In order to mitigate the sonic boom effects at ground level, some aerospace companies proposed airplanes that have a very small transversal fuselage section or that have a curved (“shaped”) fuselage. Obviously, shaping the fuselage leads to the increase of dynamic drag and manufacturing cost. Reducing the fuselage transverse section leads to reducing the useful volume inside fuselage and increases the landing distance of aircraft. The solution presented in this chapter shows that it is theoretically and technologically possible as the shock wave to be dispersed through mechanical or electrical means. The shock wave is in fact a stationary effect generated by the move of aircraft with constant speed relatively to surrounding air. If this feature is in a way or another canceled, the shock wave is dispersing. Due to dispersion of the shock wave the ‘N’ wave at the ground is tens of times larger and the sonic boom is correspondingly lower. The shock wave dispersion system of the future could be mechanical or electrical is activated only when the supersonic aircraft/space plane is flying horizontally over community.",book:{id:"7403",slug:"environmental-impact-of-aviation-and-sustainable-solutions",title:"Environmental Impact of Aviation and Sustainable Solutions",fullTitle:"Environmental Impact of Aviation and Sustainable Solutions"},signatures:"Constantin Sandu, Radu-Constantin Sandu and Cristian-Teodor Olariu",authors:[{id:"270781",title:"Dr.",name:"Constantin",middleName:null,surname:"Sandu",slug:"constantin-sandu",fullName:"Constantin Sandu"},{id:"278504",title:"BSc.",name:"Radu-Constantin",middleName:null,surname:"Sandu",slug:"radu-constantin-sandu",fullName:"Radu-Constantin Sandu"},{id:"298114",title:"Dr.",name:"Cristian–Teodor",middleName:null,surname:"Olariu",slug:"cristian-teodor-olariu",fullName:"Cristian–Teodor Olariu"}]},{id:"67061",title:"Structural Analysis of Electric Flight Vehicles for Application of Multifunctional Energy Storage System",slug:"structural-analysis-of-electric-flight-vehicles-for-application-of-multifunctional-energy-storage-sy",totalDownloads:860,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The Multifunctional Structures for High Energy Lightweight Load-bearing Storage (M-SHELLS) research project goals were to develop M-SHELLS, integrate them into the structure, and conduct flight tests onboard a remotely piloted small aircraft. Experimental M-SHELLS energy-storing coupons were fabricated and tested for their electrical and mechanical properties. In this chapter, finite element model development and structural analyses of two small test aircraft candidates are presented. The component weight analysis from the finite element model and test measurements were correlated. Structural analysis results with multifunctional energy storage panels in the fuselage of the test vehicle are presented. The results indicate that the mid-fuselage floor composite panel could provide structural integrity with minimal weight penalty while supplying electrical energy. Structural analyses of the NASA X-57 Maxwell electric aircraft and an advanced aircraft fuselage structure are also presented for potential application of M-SHELLS. Secondary aluminum structure in the fuselage subfloor and cargo area are partially replaced with reinforced five-layer composite panels with M-SHELLS honeycomb core. The fuselage weight reduction associated with each design without risking structural integrity are described. The structural analysis and weight estimation with composite M-SHELLS panels in the fuselage floor indicates 3.2% structural weight reduction, but with increased stress.",book:{id:"7403",slug:"environmental-impact-of-aviation-and-sustainable-solutions",title:"Environmental Impact of Aviation and Sustainable Solutions",fullTitle:"Environmental Impact of Aviation and Sustainable Solutions"},signatures:"Vivek Mukhopadhyay",authors:[{id:"260863",title:"Dr.",name:"Vivekananda",middleName:null,surname:"Mukhopadhyay",slug:"vivekananda-mukhopadhyay",fullName:"Vivekananda Mukhopadhyay"}]},{id:"68313",title:"The Role of CFD in Modern Jet Engine Combustor Design",slug:"the-role-of-cfd-in-modern-jet-engine-combustor-design",totalDownloads:1032,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"Recent advances in the application of computational fluid dynamics (CFD) for turbulent combustion with the relevance for gas turbine jet engines are discussed. Large eddy simulation (LES) has emerged as a powerful approach to handle the highly turbulent, unsteady and thermochemically non-linear flows in the practical combustors, and it is a matter of time for the industry to replace the conventional Reynolds averaged Navier-Stokes (RANS) approach by LES as the main CFD tool for combustor research and development. Since combustion is a subgrid scale phenomenon in LES, appropriate modelling is required to describe the SGS combustion effects on the resolved scales. Among the various available models, the flamelet approach is seen to be a promising candidate for practical application because of its computational efficiency, robustness and accuracy. A revised flamelet formulation, FlaRe, is introduced to outline the general LES methodology for combustion modelling and then used for a range of test cases to demonstrate its capabilities for both laboratory burners and practical engine combustors. The LES results generally compare well with the experimental measurements showing that the important physical processes are captured in the simulations.",book:{id:"7403",slug:"environmental-impact-of-aviation-and-sustainable-solutions",title:"Environmental Impact of Aviation and Sustainable Solutions",fullTitle:"Environmental Impact of Aviation and Sustainable Solutions"},signatures:"Zhi X. 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Considered environmental problems are intensified in connection with increasing air traffic, rising tensions of airports expansion and growing cities closer and closer each other, and accordingly growing public concern with air quality around the airport. Aircraft are the dominant and special source of emission and air pollution at airports in most cases under consideration. So, to evaluate the aircraft contribution in LAQ assessment of the airports accurately, it is important to take in mind few features of the aircraft during their landing-takeoff cycle (LTO), which define emission and dispersion parameters of the considered source. The complex model PolEmiCa allows the calculation of the inventory and dispersion parameters of the aircraft engine emissions during the LTO cycles of the aircraft in the airport area. But a clear quantification of aircraft emission contribution to total air pollution is the actual task for development of cost-effective strategies to improve local air quality according to the vicinity of the airport, and to meet regulatory requirements.",book:{id:"7403",slug:"environmental-impact-of-aviation-and-sustainable-solutions",title:"Environmental Impact of Aviation and Sustainable Solutions",fullTitle:"Environmental Impact of Aviation and Sustainable Solutions"},signatures:"Oleksandr Zaporozhets and Kateryna Synylo",authors:[{id:"280013",title:"Dr.",name:"Kateryna",middleName:null,surname:"Synylo",slug:"kateryna-synylo",fullName:"Kateryna Synylo"},{id:"289615",title:"Prof.",name:"Oleksandr",middleName:null,surname:"Zaporozhets",slug:"oleksandr-zaporozhets",fullName:"Oleksandr Zaporozhets"}]},{id:"69771",title:"A Mathematical Model of Noise Pollution in Streets of Tehran near IKIA Airport",slug:"a-mathematical-model-of-noise-pollution-in-streets-of-tehran-near-ikia-airport",totalDownloads:835,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"This chapter attempts to investigate noise pollution in the street of Tehran near IKIA airport considering the population growth and large contribution of ground vehicles to noise pollution. The operation of airports results in environmental impact associated with high levels of different sources of noise. If there is to be growth in aviation, the environmental impacts of aviation must be mitigated. In this chapter, a model for the noise pollution near IKIA airport in Tehran has been calibrated with the use of a noise forecasting software. The study areas consisted of high traffic areas of Tajrish Street near the airport. In a field study, the noise level was measured via sound meter and the noise map was generated based on geo-statistical methods via GIS software. For this purpose, the factors influencing noise level (e.g. traffic, road width, slope, and residential or administrative-commercial land use) were surveyed and recorded for each point and their local and time dependencies were computed via SPSS. According to the results obtained from 324 survey points, the highest noise levels belonged to Tajrish area (69 dB). 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He has more than sixteen years of teaching experience and has supervised numerous postgraduate and Ph.D. students. He has to his credit more than seventy papers in SCI- and SCOPUS-indexed journals, fifty-five conference proceedings, four books, six Best Paper Awards, and five projects from different government agencies. He is currently an editorial board member of eight international journals and a reviewer for more than fifty scientific journals. He received Top Reviewer and Excellent Peer Reviewer Awards from Publons in 2016 and 2017, respectively. He is also on the panel of The International Reviewer for reviewing research proposals for grants from the Royal Society. He also serves as a Publons Academy mentor and Bentham brand ambassador.",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",country:{name:"India"}}},{id:"142388",title:"Dr.",name:"Thiago",middleName:"Gomes",surname:"Gomes Heck",slug:"thiago-gomes-heck",fullName:"Thiago Gomes Heck",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/142388/images/7259_n.jpg",biography:null,institutionString:null,institution:{name:"Universidade Regional do Noroeste do Estado do Rio Grande do Sul",country:{name:"Brazil"}}},{id:"336273",title:"Assistant Prof.",name:"Janja",middleName:null,surname:"Zupan",slug:"janja-zupan",fullName:"Janja Zupan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/336273/images/14853_n.jpeg",biography:"Janja Zupan graduated in 2005 at the Department of Clinical Biochemistry (superviser prof. dr. Janja Marc) in the field of genetics of osteoporosis. Since November 2009 she is working as a Teaching Assistant at the Faculty of Pharmacy, Department of Clinical Biochemistry. In 2011 she completed part of her research and PhD work at Institute of Genetics and Molecular Medicine, University of Edinburgh. She finished her PhD entitled The influence of the proinflammatory cytokines on the RANK/RANKL/OPG in bone tissue of osteoporotic and osteoarthritic patients in 2012. From 2014-2016 she worked at the Institute of Biomedical Sciences, University of Aberdeen as a postdoctoral research fellow on UK Arthritis research project where she gained knowledge in mesenchymal stem cells and regenerative medicine. She returned back to University of Ljubljana, Faculty of Pharmacy in 2016. She is currently leading project entitled Mesenchymal stem cells-the keepers of tissue endogenous regenerative capacity facing up to aging of the musculoskeletal system funded by Slovenian Research Agency.",institutionString:null,institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"357453",title:"Dr.",name:"Radheshyam",middleName:null,surname:"Maurya",slug:"radheshyam-maurya",fullName:"Radheshyam Maurya",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/357453/images/16535_n.jpg",biography:null,institutionString:null,institution:{name:"University of Hyderabad",country:{name:"India"}}},{id:"418340",title:"Dr.",name:"Jyotirmoi",middleName:null,surname:"Aich",slug:"jyotirmoi-aich",fullName:"Jyotirmoi Aich",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038Ugi5QAC/Profile_Picture_2022-04-15T07:48:28.png",biography:"Biotechnologist with 15 years of research including 6 years of teaching experience. Demonstrated record of scientific achievements through consistent publication record (H index = 13, with 874 citations) in high impact journals such as Nature Communications, Oncotarget, Annals of Oncology, PNAS, and AJRCCM, etc. Strong research professional with a post-doctorate from ACTREC where I gained experimental oncology experience in clinical settings and a doctorate from IGIB where I gained expertise in asthma pathophysiology. A well-trained biotechnologist with diverse experience on the bench across different research themes ranging from asthma to cancer and other infectious diseases. An individual with a strong commitment and innovative mindset. Have the ability to work on diverse projects such as regenerative and molecular medicine with an overall mindset of improving healthcare.",institutionString:"DY Patil Deemed to Be University",institution:null},{id:"349288",title:"Prof.",name:"Soumya",middleName:null,surname:"Basu",slug:"soumya-basu",fullName:"Soumya Basu",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035QxIDQA0/Profile_Picture_2022-04-15T07:47:01.jpg",biography:"Soumya Basu, Ph.D., is currently working as an Associate Professor at Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India. With 16+ years of trans-disciplinary research experience in Drug Design, development, and pre-clinical validation; 20+ research article publications in journals of repute, 9+ years of teaching experience, trained with cross-disciplinary education, Dr. Basu is a life-long learner and always thrives for new challenges.\r\nHer research area is the design and synthesis of small molecule partial agonists of PPAR-γ in lung cancer. She is also using artificial intelligence and deep learning methods to understand the exosomal miRNA’s role in cancer metastasis. Dr. Basu is the recipient of many awards including the Early Career Research Award from the Department of Science and Technology, Govt. of India. She is a reviewer of many journals like Molecular Biology Reports, Frontiers in Oncology, RSC Advances, PLOS ONE, Journal of Biomolecular Structure & Dynamics, Journal of Molecular Graphics and Modelling, etc. She has edited and authored/co-authored 21 journal papers, 3 book chapters, and 15 abstracts. She is a Board of Studies member at her university. She is a life member of 'The Cytometry Society”-in India and 'All India Cell Biology Society”- in India.",institutionString:"Dr. D.Y. Patil Vidyapeeth, Pune",institution:{name:"Dr. D.Y. Patil Vidyapeeth, Pune",country:{name:"India"}}},{id:"354817",title:"Dr.",name:"Anubhab",middleName:null,surname:"Mukherjee",slug:"anubhab-mukherjee",fullName:"Anubhab Mukherjee",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y0000365PbRQAU/ProfilePicture%202022-04-15%2005%3A11%3A18.480",biography:"A former member of Laboratory of Nanomedicine, Brigham and Women’s Hospital, Harvard University, Boston, USA, Dr. Anubhab Mukherjee is an ardent votary of science who strives to make an impact in the lives of those afflicted with cancer and other chronic/acute ailments. He completed his Ph.D. from CSIR-Indian Institute of Chemical Technology, Hyderabad, India, having been skilled with RNAi, liposomal drug delivery, preclinical cell and animal studies. He pursued post-doctoral research at College of Pharmacy, Health Science Center, Texas A & M University and was involved in another postdoctoral research at Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute, Santa Monica, California. In 2015, he worked in Harvard-MIT Health Sciences & Technology as a visiting scientist. He has substantial experience in nanotechnology-based formulation development and successfully served various Indian organizations to develop pharmaceuticals and nutraceutical products. He is an inventor in many US patents and an author in many peer-reviewed articles, book chapters and books published in various media of international repute. Dr. Mukherjee is currently serving as Principal Scientist, R&D at Esperer Onco Nutrition (EON) Pvt. Ltd. and heads the Hyderabad R&D center of the organization.",institutionString:"Esperer Onco Nutrition Pvt Ltd.",institution:null},{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/319365/images/system/319365.png",biography:"Manash K. Paul is a Principal Investigator and Scientist at the University of California Los Angeles. He has contributed significantly to the fields of stem cell biology, regenerative medicine, and lung cancer. His research focuses on various signaling processes involved in maintaining stem cell homeostasis during the injury-repair process, deciphering lung stem cell niche, pulmonary disease modeling, immuno-oncology, and drug discovery. He is currently investigating the role of extracellular vesicles in premalignant lung cell migration and detecting the metastatic phenotype of lung cancer via machine-learning-based analyses of exosomal signatures. Dr. Paul has published in more than fifty peer-reviewed international journals and is highly cited. He is the recipient of many awards, including the UCLA Vice Chancellor’s award, a senior member of the Institute of Electrical and Electronics Engineers (IEEE), and an editorial board member for several international journals.",institutionString:"University of California Los Angeles",institution:{name:"University of California Los Angeles",country:{name:"United States of America"}}},{id:"311457",title:"Dr.",name:"Júlia",middleName:null,surname:"Scherer Santos",slug:"julia-scherer-santos",fullName:"Júlia Scherer Santos",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311457/images/system/311457.jpg",biography:"Dr. Júlia Scherer Santos works in the areas of cosmetology, nanotechnology, pharmaceutical technology, beauty, and aesthetics. Dr. Santos also has experience as a professor of graduate courses. Graduated in Pharmacy, specialization in Cosmetology and Cosmeceuticals applied to aesthetics, specialization in Aesthetic and Cosmetic Health, and a doctorate in Pharmaceutical Nanotechnology. Teaching experience in Pharmacy and Aesthetics and Cosmetics courses. She works mainly on the following subjects: nanotechnology, cosmetology, pharmaceutical technology, aesthetics.",institutionString:"Universidade Federal de Juiz de Fora",institution:{name:"Universidade Federal de Juiz de Fora",country:{name:"Brazil"}}},{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",biography:"Dr. Kükürt graduated from Uludağ University in Turkey. He started his academic career as a Research Assistant in the Department of Biochemistry at Kafkas University. In 2019, he completed his Ph.D. program in the Department of Biochemistry at the Institute of Health Sciences. He is currently working at the Department of Biochemistry, Kafkas University. He has 27 published research articles in academic journals, 11 book chapters, and 37 papers. He took part in 10 academic projects. He served as a reviewer for many articles. He still serves as a member of the review board in many academic journals. He is currently working on the protective activity of phenolic compounds in disorders associated with oxidative stress and inflammation.",institutionString:null,institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"178366",title:"Dr.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",biography:"Volkan Gelen is a Physiology specialist who received his veterinary degree from Kafkas University in 2011. Between 2011-2015, he worked as an assistant at Atatürk University, Faculty of Veterinary Medicine, Department of Physiology. In 2016, he joined Kafkas University, Faculty of Veterinary Medicine, Department of Physiology as an assistant professor. Dr. Gelen has been engaged in various academic activities at Kafkas University since 2016. There he completed 5 projects and has 3 ongoing projects. He has 60 articles published in scientific journals and 20 poster presentations in scientific congresses. His research interests include physiology, endocrine system, cancer, diabetes, cardiovascular system diseases, and isolated organ bath system studies.",institutionString:"Kafkas University",institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"418963",title:"Dr.",name:"Augustine Ododo",middleName:"Augustine",surname:"Osagie",slug:"augustine-ododo-osagie",fullName:"Augustine Ododo Osagie",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/418963/images/16900_n.jpg",biography:"Born into the family of Osagie, a prince of the Benin Kingdom. I am currently an academic in the Department of Medical Biochemistry, University of Benin. Part of the duties are to teach undergraduate students and conduct academic research.",institutionString:null,institution:{name:"University of Benin",country:{name:"Nigeria"}}},{id:"192992",title:"Prof.",name:"Shagufta",middleName:null,surname:"Perveen",slug:"shagufta-perveen",fullName:"Shagufta Perveen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192992/images/system/192992.png",biography:"Prof. Shagufta Perveen is a Distinguish Professor in the Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Dr. Perveen has acted as the principal investigator of major research projects funded by the research unit of King Saud University. She has more than ninety original research papers in peer-reviewed journals of international repute to her credit. She is a fellow member of the Royal Society of Chemistry UK and the American Chemical Society of the United States.",institutionString:"King Saud University",institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"49848",title:"Dr.",name:"Wen-Long",middleName:null,surname:"Hu",slug:"wen-long-hu",fullName:"Wen-Long Hu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49848/images/system/49848.jpg",biography:"Wen-Long Hu is Chief of the Division of Acupuncture, Department of Chinese Medicine at Kaohsiung Chang Gung Memorial Hospital, as well as an adjunct associate professor at Fooyin University and Kaohsiung Medical University. Wen-Long is President of Taiwan Traditional Chinese Medicine Medical Association. He has 28 years of experience in clinical practice in laser acupuncture therapy and 34 years in acupuncture. He is an invited speaker for lectures and workshops in laser acupuncture at many symposiums held by medical associations. He owns the patent for herbal preparation and producing, and for the supercritical fluid-treated needle. Dr. Hu has published three books, 12 book chapters, and more than 30 papers in reputed journals, besides serving as an editorial board member of repute.",institutionString:"Kaohsiung Chang Gung Memorial Hospital",institution:{name:"Kaohsiung Chang Gung Memorial Hospital",country:{name:"Taiwan"}}},{id:"298472",title:"Prof.",name:"Andrey V.",middleName:null,surname:"Grechko",slug:"andrey-v.-grechko",fullName:"Andrey V. Grechko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/298472/images/system/298472.png",biography:"Andrey Vyacheslavovich Grechko, Ph.D., Professor, is a Corresponding Member of the Russian Academy of Sciences. He graduated from the Semashko Moscow Medical Institute (Semashko National Research Institute of Public Health) with a degree in Medicine (1998), the Clinical Department of Dermatovenerology (2000), and received a second higher education in Psychology (2009). Professor A.V. Grechko held the position of Сhief Physician of the Central Clinical Hospital in Moscow. He worked as a professor at the faculty and was engaged in scientific research at the Medical University. Starting in 2013, he has been the initiator of the creation of the Federal Scientific and Clinical Center for Intensive Care and Rehabilitology, Moscow, Russian Federation, where he also serves as Director since 2015. He has many years of experience in research and teaching in various fields of medicine, is an author/co-author of more than 200 scientific publications, 13 patents, 15 medical books/chapters, including Chapter in Book «Metabolomics», IntechOpen, 2020 «Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology».",institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"199461",title:"Prof.",name:"Natalia V.",middleName:null,surname:"Beloborodova",slug:"natalia-v.-beloborodova",fullName:"Natalia V. Beloborodova",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/199461/images/system/199461.jpg",biography:'Natalia Vladimirovna Beloborodova was educated at the Pirogov Russian National Research Medical University, with a degree in pediatrics in 1980, a Ph.D. in 1987, and a specialization in Clinical Microbiology from First Moscow State Medical University in 2004. She has been a Professor since 1996. Currently, she is the Head of the Laboratory of Metabolism, a division of the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russian Federation. N.V. Beloborodova has many years of clinical experience in the field of intensive care and surgery. She studies infectious complications and sepsis. She initiated a series of interdisciplinary clinical and experimental studies based on the concept of integrating human metabolism and its microbiota. Her scientific achievements are widely known: she is the recipient of the Marie E. Coates Award \\"Best lecturer-scientist\\" Gustafsson Fund, Karolinska Institutes, Stockholm, Sweden, and the International Sepsis Forum Award, Pasteur Institute, Paris, France (2014), etc. Professor N.V. Beloborodova wrote 210 papers, five books, 10 chapters and has edited four books.',institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"354260",title:"Ph.D.",name:"Tércio Elyan",middleName:"Azevedo",surname:"Azevedo Martins",slug:"tercio-elyan-azevedo-martins",fullName:"Tércio Elyan Azevedo Martins",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/354260/images/16241_n.jpg",biography:"Graduated in Pharmacy from the Federal University of Ceará with the modality in Industrial Pharmacy, Specialist in Production and Control of Medicines from the University of São Paulo (USP), Master in Pharmaceuticals and Medicines from the University of São Paulo (USP) and Doctor of Science in the program of Pharmaceuticals and Medicines by the University of São Paulo. Professor at Universidade Paulista (UNIP) in the areas of chemistry, cosmetology and trichology. Assistant Coordinator of the Higher Course in Aesthetic and Cosmetic Technology at Universidade Paulista Campus Chácara Santo Antônio. Experience in the Pharmacy area, with emphasis on Pharmacotechnics, Pharmaceutical Technology, Research and Development of Cosmetics, acting mainly on topics such as cosmetology, antioxidant activity, aesthetics, photoprotection, cyclodextrin and thermal analysis.",institutionString:null,institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"334285",title:"Ph.D. Student",name:"Sameer",middleName:"Kumar",surname:"Jagirdar",slug:"sameer-jagirdar",fullName:"Sameer Jagirdar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334285/images/14691_n.jpg",biography:"I\\'m a graduate student at the center for biosystems science and engineering at the Indian Institute of Science, Bangalore, India. I am interested in studying host-pathogen interactions at the biomaterial interface.",institutionString:null,institution:{name:"Indian Institute of Science Bangalore",country:{name:"India"}}},{id:"329248",title:"Dr.",name:"Md. Faheem",middleName:null,surname:"Haider",slug:"md.-faheem-haider",fullName:"Md. Faheem Haider",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329248/images/system/329248.jpg",biography:"Dr. Md. Faheem Haider completed his BPharm in 2012 at Integral University, Lucknow, India. In 2014, he completed his MPharm with specialization in Pharmaceutics at Babasaheb Bhimrao Ambedkar University, Lucknow, India. He received his Ph.D. degree from Jamia Hamdard University, New Delhi, India, in 2018. He was selected for the GPAT six times and his best All India Rank was 34. Currently, he is an assistant professor at Integral University. Previously he was an assistant professor at IIMT University, Meerut, India. He has experience teaching DPharm, Pharm.D, BPharm, and MPharm students. He has more than five publications in reputed journals to his credit. Dr. Faheem’s research area is the development and characterization of nanoformulation for the delivery of drugs to various organs.",institutionString:"Integral University",institution:{name:"Integral University",country:{name:"India"}}},{id:"329795",title:"Dr.",name:"Mohd Aftab",middleName:"Aftab",surname:"Siddiqui",slug:"mohd-aftab-siddiqui",fullName:"Mohd Aftab Siddiqui",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329795/images/system/329795.png",biography:"Dr. Mohd Aftab Siddiqui is an assistant professor in the Faculty of Pharmacy, Integral University, Lucknow, India, where he obtained a Ph.D. in Pharmacology in 2020. He also obtained a BPharm and MPharm from the same university in 2013 and 2015, respectively. His area of research is the pharmacological screening of herbal drugs/natural products in liver cancer and cardiac diseases. He is a member of many professional bodies and has guided many MPharm and PharmD research projects. Dr. Siddiqui has many national and international publications and one German patent to his credit.",institutionString:"Integral University",institution:null}]}},subseries:{item:{id:"3",type:"subseries",title:"Bacterial Infectious Diseases",keywords:"Antibiotics, Biofilm, Antibiotic Resistance, Host-microbiota Relationship, Treatment, Diagnostic Tools",scope:"