\r\n\tCKs have crucial roles in various viral infections such as influenza, hepatitis B virus (HBV), hepatitis C virus (HCV), viral meningitis, human immunodeficiency virus (HIV), and SARS-CoV-2.
\r\n\tCKs mediate the directing of the transport of leukocyte cells into the tumor microenvironment to generate the host response against cancer. CKs can directly modulate tumor tissue expansion by inducing the proliferation of cancerous cells and inhibiting their apoptosis. They can also indirectly modulate the growth of tumor tissue through the effects of CKs on tumor stromal cells, by inducing the release of growth and angiogenic factors of cells that make up the tumor microenvironment.
How do γ-rays compare with other types of radiation? “Radiation” in common language describes “energy packages” that travel on straight paths. “Electromagnetic radiation” is characterized by variations of electric and magnetic fields in space and time. Another type of “radiation” is “cosmic rays,” very energetic particles discovered early in the twentieth century in the upper atmosphere of the Earth and known to pervade interstellar space. These particles are called “cosmic radiation” because with their high energies they propagate at the speed of light and in certain aspects behave like photons of similar energies [1].
\nGamma radiation represents the most energetic part of the electromagnetic spectrum (\nFigure 1\n). Therefore, it is natural that it provides information about the liveliest procedures and wonders in the universe [2].
\nThe electromagnetic spectrum from radio to γ-ray energies. The electromagnetic radiation can be characterized by its photon energy (measured in eV), by its frequency (measured in Hz) or by its wavelength (measured in m) [
In general, there are three noteworthy sources: earthly radiation, grandiose radiation, and interior radiation due to the admission of regular radionuclides through inward breath (for the most part radon) and ingestion. Additionally, the most three radionuclide components are thorium (232Th), potassium (40K), and uranium (238U). Natural radiation sources consolidate the ground, rocks, air, building materials, and drinking water supplies. Big amount of radiation rises up out of sun situated, galactic and extragalactic transmissions and contains decidedly charged particles, muons, neutrons, and gamma radiation.
\nInward radiation is in our body because of what we eat and drink and the air we unwind. Common radiation in a general sense relies upon topographical and geological conditions. In this way, the portion ratios of both enormous and earthbound gamma radiation will be found to vary depending upon where the estimations are made [3, 4, 5].
\nAs the research shows the relationship between the gamma-ray and living beings and all gamma radiation in the earth, it will explain in detail the mechanisms (according to the user of the detector) to calculate gamma background radiation and the measurements depending on the international standard values.
\nThis section explains the most common detectors used in the measurement of gamma background radiation and equipped with the international practical recent researches, to let the researchers who have worked in this field have the basic knowledge on these devices by knowing the mechanism of how they work and how to calculate gamma background radiation.
\nA radiation dosimeter is a gadget, instrument, or framework that measures or assesses specifically or in a roundabout way, the amounts presentation, KERMA, proportional portion, or when they again their time auxiliaries (rates), or related amounts of ionizing radiation. A dosimeter close by its scrutinize is insinuated as a dosimetry structure.
\nEstimation of a dosimetric aggregate is the course toward finding the respect of the total likely utilizing dosimetry frameworks. The delayed consequence of estimation is the estimation of a dosimetric aggregate imparted as the aftereffect of a numerical regard and a reasonable unit. To fill in as a radiation dosimeter, the dosimeter must have no short of what one physical property that is a component of the intentional dosimetric sum and that can be used for radiation dosimetry with the real arrangement. With the ultimate objective to be significant, radiation dosimeters must show a couple of appealing characteristics.
\nFor instance, in radiotherapy, correct information of both the consumed portion of water at a predefined point and its spatial appropriation are of significance, also the likelihood of determining the portion to an organ of enthusiasm for the patient [6]. In radiation, preparing dosimetry is utilized to evaluate the vitality kept in a material or consumed by a human from radiation sources.
\nDiverse dosimetry frameworks are utilized for various purposes in industry and research light offices, which have distinctive prerequisites for portion conclusions. Radiation wellbeing norms and issues including the radiation safety of people against radiation presentation have their very own dosimetry metrology.
\nRadiation dosimeters and dosimetry frameworks come in numerous shapes and structures and they depend on various physical impacts for capacity and readout of the dosimetric flag. The below table demonstrates the most regularly utilized of dosimetric frameworks, and the qualities and shortcomings of these four dosimeters are outlined. The four most commonly used radiation dosimeters are [6]:
Ionization chambers
Radiographic films
TLDs
Diodes
Dosimetry type | \nAdvantage | \nDisadvantage | \n
---|---|---|
Ionization chambers | \nAccurate and precise. Recommended for beam calibration. Necessary corrections well understood. Instant readout. | \nConnecting cables required. High voltage supply required. Many corrections required for high energy beam dosimetry. | \n
Radiographic films | \n(2-D) spatial goals. Thin: does not irritate the pillar. | \nDarkroom and preparing offices required. Preparing hard to control variety among movies and clumps. Needs legitimate alignment against ionization chamber estimations. Energy reliance issues can’t be utilized for pillar alignment. | \n
TLDs | \nSmall in size: point portion estimations conceivable. Numerous TLDs can be uncovered in a solitary presentation. Accessible in different structures such as some similar tissue identical. Not costly. | \nFlag deleted amid readout. Simple to lose perusing. No moment readout. Precise outcomes require care readout and alignment tedious. Not suggested for shaft calibration. | \n
Diodes | \nLittle size. High affectability. Moment readout. No outer inclination voltage basic instrumentation. | \nRequires partner joins Variability of alteration with temperature. Change in affectability with the aggregated portion. Uncommon consideration expected to guarantee consistency of reaction. Can’t be utilized for pillar adjustment. | \n
Radiation dosimetry is a part of physical science investigating diverse strategies for the quantitative assurance of vitality, which is stored in a given material by ionizing radiation, either through an immediate or aberrant presentation. Dosimetry manages conclusions and computations of amounts (portion) that depict the vitality ingested in a material and to some degree its rate of the statement (portion rate). Dosimetry conclusions that are performed by presenting a dosimeter to a radiation source help in assessing the radiation-prompted impacts, physical, substance, and additionally organic, on a lighted material [7]. \nFigure 2\n shows a Science Photo Library/Getty Images [8].
\nScience Photo Library/Getty Images [
Know the most recent research to calculate gamma background radiation is measurements of gamma background radiation in Lorestan, Iran.
\nThe researcher used a G.M. detector (RDS-110) “Inspector Alert model RAP RS1, S.E. international, Inc, USA”. The outcome demonstrates the normal yearly powerful portion for gamma base radiation in Lorestan area has been 0.72 mSv, with the scope of 0.3–0.6 mSv which was more than the worldwide esteem (0.48 mSv). A poor coefficient relationship in-between was noticed elevating and retaining portion rates [9].
\nAnother research study used the same device and the same properties. Indoor and outdoor absorbed dose rates were measured in the select region of AL-Qizweenia Najaf in Iraq [10]. Many studies in the gamma field of background radiation were conducted in different cities of Iraq [11, 12, 13]. All values of these studies compared with limitation of world average values.
\nThere was an expansive glitter phenomenon in 1948 which was accounted for. It caused by including a follow amount of thallium (Tl) into a precious stone of sodium iodide (NaI). This identifier, in which sodium iodide (NaI) was utilized for radiation estimations, was based on the fact that recently it had been produced by HORIBA. They had the advancement of the NaI(Tl) plate for gamma cameras began during the 1970s.
\nIn the first place, gems with breadths of 1–3 inches were utilized as indicators for atomic material science tests, natural radiation estimations at atomic power plants, or radioimmunoassay. Furthermore, mosaic-type precious stones were likewise created to relate to vast estimated gems notwithstanding the gems with a distance across of around 5 inches. After the expansive estimated gamma camera was created, bigger and bigger precious stones have been requested each year, and researchers have been making a decent attempt to get ever bigger measured NaI(Tl) gems as of late, and \nFigure 3\n shows atypical scintillation detector [14].
\nAtypical scintillation detector [
An elective strategy for assurance of exercises of regular, techno genic, and aftermath radionuclide in natural examples was proposed. The strategy utilized a broadly accessible shine spectrometer and depended on the disintegration of tests’ γ-spectra into ghastly segments of discrete radionuclide bunches with the assistance of standard sources. The technique was tested on water, soil, and coal which could be effectively utilized in field (endeavor) conditions (without fluid nitrogen for the indicator cooling) [15].
\nThere were many local and international studies used NaI(Tl) detector to evaluate natural or terrestrial of radionuclide or gamma background radiation with a difference of accuracy and efficiency of the device and sometimes equipped with a software program of the trace elements.
\nIn 2013, a nearby report discusses uranium (238U), thorium (232Th), and potassium (40K) with the explicit movement (10) in a few types of vegetables that is accessible at the market in Iraq. Tests had been estimated, and inner risk file, radium identical, and the yearly compelling portion of (40K) in all examples were resolved. The gamma spectrometry methodology with a NaI(Tl) pointer was used for radiometric estimations, outcomes were contrasted and worldwide prescribed qualities and were observed to be inside the global dimension [16].
\nAn investigation was conducted on radionuclides (226Ra, 232Th, and 40K) of natural radioactivity estimations and assessment of radiological hazards in the silt of Oguta Lake, South East Nigeria. NaI(Tl) indicator “(show: Bicron, Pre-intensifier model:2001, Amplifier model:2020, ADC model:8075, HVPS model:3105)” was utilized for the gamma-beam spectrometry estimations. The identifier has a goal of 8% at 0.665 MeV line of 137Cs, which is equipped for recognizing the gamma-beam energies of the radionuclides of enthusiasm for this examination. The investigation could fill in as critical radiometric pattern information whereupon future epidemiological examinations and ecological observing activities could be based [17].
\nAnother examination enduring gamma producers in biscuit samples expired in Iraq, estimated the common radioactivity couple to seemingly perpetual gamma producers in children roll by gamma spectroscopy and appraisal radiation risk records which are the radium comparable action, the delegate of gamma level file, the interior danger file, and yearly powerful portion in kids. The gamma spectrum from each sample was recorded using detector NaI(Tl), and the volume of the crystal is (“3 × 3”), a PC-based multichannel analyzer (4096 channel) and processed using the MAESTRO-32 software. The estimations of eexpress activity, radiation risk records, and a yearly viable portion in all examples in this investigation are discovered lower than the overall middle incentive for all gatherings. Along these lines, these qualities are observed to be protected [18].
\nThree types of research are in the same field (used NaI detector). First one is in Kütahya, Turkey. The examination of common radioactivity from 238U, 232Th, and 40K in 357 soil tests gathered from territory of Kütahya was completed utilizing a NaI(Tl) gamma-beam spectroscopy. Explicit exercises of 238U, 232Th, and 40K in the dirt examples were assessed. The locator was coupled to a full-featured 16 K channel fused multichannel analyzer “(Canberra DSA-1000).” It is joined with a PC for getting an examination and with reasonable programming “(Genie 2000).”
\nThe identifier was covered in a 0.5 cm thickness lead shield, giving a disguise of the establishment gamma-bar radiation present in the exploration office. The NaI(Tl) gamma-bar spectrometer has high efficiency, and in a similar manner, it might be used for the customary radioactivity. The outcomes acquired in this examination were analyzed inside the cutoff points of values gotten in different urban areas of Turkey, those in different nations [19].
\nSecond research estimated normal radioactivity in chosen tests of therapeutic plants in Iraq, where characteristic dimensions of radiation in some chosen therapeutic plants existing in the Iraqi stores were assessed to decide any action fixation, radium comparable, and inner risk file due to the radionuclide, of 238U, 232Th, and in addition 40K, which happens normally. The movement fixation is recognized by gamma-beam spectroscopy and NaI(Tl). Estimations are done by embracing frameworks of gamma spectrometry from ORTEC, furnished with a high productivity sparkle indicator, a NaI(Tl) locator of (3″ × 3″) precious stone measurement, with goals 9.2% for 137Cs (661.7 keV). A lead shield with a thickness of (10 cm) was put around the finder to decrease the foundation, with a 0.3 cm layer of copper to debilitate X-rays discharged by the lead shield. The spectra were seen disconnected utilizing the ORTEC Maestro-32 information obtaining and examination framework. Regular radionuclides and development of the radium similar to the remedial plant tests were far underneath the world for the ingestion of typically happening radionuclide, as given in UNSCEAR 2000 report [20].
\nThird research in some vegetables and fruits commonly used in Najaf Governorate, Iraq, determined the natural radioactivity levels. The points of the present work were to gauge the explicit action and yearly compelling portion because of the admission of vegetables and organic products gathered from the nearby market in Najaf governorate. Characteristic radioactivity was estimated in tests utilizing gamma beam spectrometer. Gamma-ray spectroscopy with scintillation detector NaI(TI) from ORTEC had an active area of “3 × 3” inches, the efficiency of 4.6% at the 662 KeV, and energy resolution 7.9%. The qualities found for explicit action and the yearly powerful portion in all examples in this investigation were lower than overall middle qualities for all gatherings as indicated by UNSCEAR (2000) and ICRP (1996) individually; subsequently, these qualities are observed to be sheltered [21].
\nAlso, a study in Turkey for the three radionuclide elements (226Ra, 232 Th, and 40K) had been made in some granite samples. The action grouping of primordial radionuclides in rock tests was assessed by utilizing (3 × 3) NaI(Tl) indicator-based gamma-beam spectrometry. This gamma spectrometer has vitality goals 8% for 662 keV and the relative checking productivity about 20%. It was critical that the productivity adjustment of the framework ought to be made before estimation for the right outcome. Estimation of radioactivity for, 14 various types of stone examples have been breaking down for their regular radioactivity content. The end was: the 40K action focus levels in stone examples in these investigations were lower than fixation estimations of various examinations on the planet. A few examples and other stone examples were not observed to be reasonable for utilizing in the human life regions due to every single radiological incentive in these examples are higher than CLV [22].
\nRoentgen in 1928 was held onto as a unit to describe radiation introduction. Roentgen evaluates the number of electrons made in air, yet not the genuine damage following in a man.
\nIn 1953, a unit known as a rad (100 ergs g−1) was grasped to portray the proportion of essentialness spared in a material. Clearly, it was found that different sorts of radiation affected the tissue in the body all of a sudden. Another unit was made to address this, known as a rem. A rem is proportionate to a rad duplicated by a factor known as a “Quality Factor” (Q) which numerically portrays the relative trademark impact of the express kind of radiation. As these new units of measure were made and executed, new radiation materials and exposure instruments were delivered with the objective that contradictory exposures and doses could be accurately evaluated [23].
\nAlthough extremely accurate active radiation detectors are now available, TLDs are small, inexpensive, and if the correct material is chosen, tissue equivalent. They can be used to detect photons, beta particles, and slow neutrons, and with appropriate filters, they can be used to determine the shallow and deep dose. Their biggest advantage is long-term deplorability, possible due to a power source being unnecessary until readout. This allows time-efficient monitoring of typically uninhabited areas. In order to ensure accurate results from long deployments in diverse interior and exterior environments, various aspects of their performance must be examined. This work serves to improve the effectiveness of TLD systems by analyzing several factors which may affect the sensitivity and precision of TLD measurements, as well as determining a practical minimum detectable dose incorporating those factors.
\nTLDs must be individually calibrated, meaning that the amount of signal response to a known dose must be measured before use. The light response to doses generally between 0.1 mGy and 10 Gy, but varying by material, has a two linear relationship with dose. This makes calibration at only one dose necessary if staying within the linear range [24]. \nFigure 4\n below shows the thermoluminescence detector (model THERMO SCIENTIFIC 4500 TLD READER) in the laboratory at Ankara University, Institute of nuclear sciences [25].
\nTHERMO SCIENTIFIC 4500 TLD READER [
Some examples of modern researches will be taken. Researches of detector will show it had much application with different branches in physical science. First one in network communication in which the point is to seek after an ordinary free quality review in Czech radiotherapy focuses and to help state supervision. The results appears to be that there are 34 radiotherapy focuses in the Czech Republic. They experience the essential method of the TLD review routinely at regular intervals.
\nOn the off chance that an inside demonstrates a deviation outside the acknowledgment level, it is evaluated more frequently. Step by step, a large portion of the checked shafts conform to the acknowledgment level.
\nResults were for the most part inside as far as possible for the estimations on-hub, though for off-hub focuses they fell past the limit all the more oftentimes, particularly for set-ups with in-homogeneities, diagonal occurrence, and wedges.
\nThe outcomes demonstrate the significance of the national TLD quality affirmation arrange. It has added to the enhancement of clinical dosimetry in the Czech Republic. What’s more, it causes administrative specialist to screen successfully and consistently radiotherapy focuses [26].
\nAn exploration in therapeutic material science including patients and apparition dosimetry in the two cases, thermoluminescence dosimetry (TLD) is the most suitable strategy for estimating the assimilated portion. In this chapter, thermoluminescence wonder and in addition the utilization of TLD in radiodiagnosis and radiotherapy for in vivo or in apparition estimations is talked about. A few aftereffects of estimations made in radiotherapy and radio diagnosis utilizing natively constructed LiF: Mg, Cu, P + PTFE TLD are exhibited [27].
\nIn nuclear atomic material science, an examination in the robust assurance of successful nuclear numbers for electron together with “TLD-100 and TLD-100H thermoluminescent dosimeters,” lithium fluoride thermoluminescent dosimeters (TLD) are frequently not completed for clinical dosimetry. The little physical enormity of TLDs makes them applicable, for instance, little field estimation, in vivo dosimetry, and estimation of out-of-field bits of essential structures. The most exhaustively used TLD can’t avoid being “TLD-100 (LiF: Mg, Ti),” and for applications requiring higher affectability to low-parcels, TLD-100H (LiF: Mg, Cu, P) is consistently used. The radiological properties of these TLDs are along these lines of significant interest. All of a sudden, in this examination, convincing atomic numbers for radiative, collisional, and mean electron association frames is resolved for “TLD-100 and TLD-100H” dosimeters over the essential expansion of 1 keV–100 MeV. This is applied by using a solid, essentialness subordinate system for calculation instead of normal power-law approximations. The effect of dopant obsessions and unwanted impacts is further analyzed. The two TLDs show relative convincing atomic numbers, generally ranging from 5.77 to 6.51. Differentiations rising up out of the particular dopants are most enunciated in low-imperativeness radiative effects. The TLDs have atomic numbers around (1.48–2.06) events than that of water [28].
\nMeasurement of computed tomography dose profile with pitch variation uses Gafchromic XR-QA2 and thermoluminescence dosimeter (TLD). This examination was meant to point the examples of portion profile on a grown-up and pediatric head filter. They thought about estimation depended on portion profile along the z-hub turn at peripheries and focus apparition with an assortment of the pitch, that is, 0.75, 1, and 1.5 for grown-up and pediatric head convention, keeping whatever is left of the sweep parameters steady.
\nEstimations were performed on homogeneous, round, and void PMMA ghost with widths of 16 and 10 cm utilizing XR-QA2 Gafchromic film and TLD as dosimeters. The estimation result showed a diminishing in the part about half and 47% for grown-up and pediatric head check with the advancement of pitch. Part profile for adult and pediatric head channel traditions has configuration twist with the most outrageous bit in the inside and inclination of symmetry near the edges, with difference in the dimension length along z-center point bearing incomprehension to the estimation position in the nebulous vision [29].
\nA research related with nuclear physics was unfolding neutron spectra from the simulated response of thermoluminescence dosimeters, and neutron spectrometry utilizing a solitary circle containing dosimeters has been produced as of late, as a powerful swap for Bonner circle spectrometry. The purpose of the examination is spreading out the neutron essentialness spectra using the GRNN fake neural framework, from the response of thermoluminescence dosimeters, TLDs, arranged inside a polyethylene circle. The spectrometer was reproduced using MCNP5.
\nTLD-600 and TLD-700 dosimeters were replicated in different positions all over. By then, the GRNN was used for neutron spectrum gauge, using the TLDs’ readings. Examination of spectra foreseen by the framework with real spectra shows that the single-circle dosimeter is an incredible instrument in spreading out neutron spectra [30].
\nSolid state physic took apart with thermoluminescence detector, preliminary studies of thermoluminescence dosimeter “(TLD) CaSO4: Dy Synthesis. thermoluminescence dosimeter (TLD) CaSO4: Dy” was orchestrated by coprecipitation.
\nThe TLD was seen after radiation introduction to Strontium-90. The thermoluminescence drive was scrutinized using a TLD Reader Harshaw 3500. The thermoluminescent response obtained was 59.29 nC. By then, refortifying was driven with the temperature vacillated at 700, 800, and 900°C. The thermoluminescent control got at temperatures of 700–900°C was 66.12, 169.45, and 552.37 nC independently. The affectability of the TLD extended in light of the retoughening temperature rise. Despite viewing the thermoluminescence properties, a relationship was made between the TLD got from this attempt distinctive things with a current TLD in the market. At long last, likewise, the gleam bend attributes of the TLD were watched [31].
\nThe U.S. Naval force utilizes the “Harshaw 8840/8841 dosimetric (DT-702/PD)” framework, which utilizes LiF: Mg, Cu, P thermoluminescent dosimeters (TLDs), created and delivered by Thermo Fisher Scientific (TFS). The dosimeter comprises four LiF: Mg, Cu, P components, mounted in Teflon on an aluminum card and put in a possessor made from plastic. The possessor consists of an interesting channel for each chip made of copper.
\nThe Naval Dosimetry Center (NDC) has created and tried another nondamaging method, which empowers the check and the assessment of installed channels in the possessors. Testing depends on weakening estimations of low-vitality radiation transmitted through each channel in an agent test gathering of possessors to confirm that right channel type and thickness are available. The deliberate reaction proportions are then contrasted and the normal reaction proportions. Moreover, every component’s deliberate reaction is contrasted with the mean reaction of the gathering. The test was organized and endeavored to recognize basic singularities, for instance, missing copper or tin channels, twofold copper or twofold tin channels, or diverse discords that may influence TLD response extents. In the midst of the execution of the made strategy, testing revealed a possessor with a twofold copper channel. To finish the assessment, the effect of the qualifications on limit testing was destitute down. The examination uncovered disappointments in capacity testing orders III and IV when these dosimeters were edified to high-significance betas [32].
\nThe diode indicator is the least difficult and most essential type of abundancy tweak, AM locator, and it distinguishes the envelope of the AM flag as shown in \nFigure 5\n. The AM diode locator could be worked only on a diode with couple of different segments, and therefore it is a minimal effort circuit hinder inside a general recipient. Because of its expense and comfort, the AM diode envelope identifier has been broadly utilized for a long time in transistor compact radios.
\nCircuit of an envelope locator as utilized in an AM radio collector [
In changing the RF hail, the AM diode discoverer gives a yield proportionate to the envelope of one part of the banner, and this implies an envelope locator. In context of the errand of the diode marker, it may every so often be implied as an envelope discoverer. The moving toward abundancy changed RF hail includes a waveform of both positive and negative going voltages as shown in \nFigure 6\n. Any stable transducer would not respond to that.
\nAM diode envelop detection process [
The diode envelope discoverer changes the waveform leaving only the positive or negative segment of the waveform. The high repeat part of this is filtered through, normally using a capacitor that outlines the low pass channel and suitable “fills” in the high repeat segments, leaving a waveform to which a transducer like two or three earphones or an enhancer could respond to and convert into sound waves.
\nThe AM diode envelope discoverer had been viably used to quite a while. The most envelope pointer purposes of intrigue are: ease that means the diode indicator just requires the utilization of a couple of ease parts. This means it is perfect for use in transistor (and valve/vacuum tube) radios utilizing discrete segments, effortlessness means utilizing not a lot of parts, and the diode AM identifier was definitely not hard to complete. It was dependable and did not need any setup, while an envelope identifier inconveniences are:
\nAs the diode indicator is nondirect, it presents mutilation onto the identified sound flag.
\nOne of the issues a significant part of the time experienced on the short and medium wavebands where the AM transmissions are found is that of express darkening. The diode envelope identifier cannot battle the impacts of this on how some different locators are capable, and therefore, contortion happens when specific blurring happens.
\nThe diode locator is not as precarious as some remarkable sorts. On the off chance that silicon diodes are utilized, these have a turn-on voltage of around 0.6 volts, and therefore, germanium or Schottky diodes are utilized which have a lower turn-on voltage of around 0.2–0.3 volts. Without a doubt, even with the utilization of the Schottky diode, the diode envelope identifier still experiences a pore estimation of affectability.
\nThe AM diode envelope indicator has been accessible for a long time. Despite the fact that abundancy balance is utilized less nowadays, and different types of AM finder can be effortlessly consolidated into coordinated circuits, the basic diode identifier still has a few points of interest [33].
\nAfter a brief explanation about diode detector, some recent applications of diode detector will be discussed.
\nIn remedial material science, in light of the way is that the skin diode is made on a thin epitaxial layer and bundled utilizing the “drop-in” advancement. It was portrayed comparably as rate hugeness isolate, segment linearity, and section rate reliance and benchmarked against the Attix ionization chamber. The reaction of the skin diode in the enhancement zone of the rate importance divide touch of a 6 MV clinical photon bar was explored. The radiation hardness of the skin diode up to an amassed bit of 80 kGy using photons from a Co-60 gamma source was surveyed [34].
\nAnother application in the same field is evaluation of the dosimetric properties of a diode detector for small field proton radiosurgery; the little fields and sharp angles regularly experienced in proton radiosurgery require high spatial goal dosimetric estimations, particularly underneath 1–2 cm measurements. The radiochromic film gives high goals; however, it requires postprocessing and unique taking care of. Promising choices are diode identifiers with little delicate volumes (SV) that are able to do high goals and continuous portion obtaining.
\nIn this investigation, the analyst assessed the PTW PR60020 proton dosimetry diode utilizing radiation fields and shaft energies pertinent to radiosurgery applications [35].
\nSchottky diode is well know; therefore, we have given examples. The first one is calculating the diode junction resistance variations with RF power of a series Schottky diode detector. Based on the Ritz-Galerkin method, this research provides a simple formula that can be used to calculate the differential input impedance and frequency response of a diode detector. Calculated results are presented for several circuit configurations that are confirmed by ADS [36].
\nThe second example is high-resolution Schottky CdTe diode detector, with a Schottky intersection created on the Te face of a top-notch CdTe semiconductor by dissipating indium, and they have possessed the capacity to accomplish a CdTe diode including high vitality goals. The identifiers demonstrate the best execution when they utilize a moderately thin locator of 1 mm. The high vitality goals of the CdTe diode are exceptionally alluring for hard X-beam and gamma-beam recognition. Particularly, an extensive CdTe diode with measurements bigger than 20 × 20 mm can possibly supplant shine locators because of its high ceasing force and vitality goals of 3 keV at 100 keV. Numerous ideas dependent on high goal CdTe diodes are currently being examined, and model indicators are being created [37].
\nSemiconductor identifiers are basically strong state analogs of gas-filled ionization chambers. Since the strong indicator materials utilized in semiconductor identifiers are 2000 to multiple times more than gases, they have the much better halting force and are considerably more productive finders for X-rays and γ-rays.
\nSemiconductor indicators regularly are poor electrical transmitters; when they were ionized by an ionizing radiation event, the electrical charge delivered could be gathered by an outer connected voltage, for what its worth with gas-filled locators. This guideline could not be connected utilizing a leading material for the locator (e.g., a square of metal) on the grounds that such a material would direct a lot of current even without ionizing occasions. Protectors (e.g., glass) are not appropriate identifier materials either on the grounds that they don’t lead even within the sight of ionizing radiation. Subsequently, just semiconductor materials can work as “strong ionization chambers.”
\nThe most by and large used semiconductor locator materials are silicon (Si) and germanium (Ge). Even more starting late, cadmium telluride (CdTe) or cadmium zinc telluride (CZT) has been utilized as the major material in insignificant atomic medicine checking and imaging gadgets. One ionization is made per 3–5 eV of radiation importance consumed. By examination, this propelling power for gases (air) is around 34 eV for each ionization. Subsequently, a semiconductor locator not exclusively is more fruitful shield of radiation, in any case, passes on an electrical standard that is around various events more prominent (per unit of radiation centrality ingested) than a gas-filled pioneer. The flag is sufficiently enormous to allow recognizing verification and checking of individual radiation occasions. Also, the proportion of the electrical banner is relating to the proportion of radiation imperativeness acclimatized. Thusly, semiconductor discoverers can be used for essentialness explicit radiation counting [38].
\nThe most advantage of HPGe high purity germanium detectors (HPGe) is the best energy resolution among all detector types. In principle, they work like reverse biased diodes; energy deposition by nuclear radiation causes the flow of a current, which is processed by front-end electronics [39]. \nFigure 7\n shows a geometrical dimension of the investigated detector (mm).
\nA geometrical dimension of the investigated detector (mm) [
In 2018, many international studies are about gamma background radiation and using HPGe detector. One of these studies is treating illnesses for many years all over the world. The aim of this study is to determine the radioactivity levels in some anti-carcinogenic medicinal plants that are often used to treat illnesses in Turkey.
\nThe analysis of 226Ra, 232Th, 40K, and 137Cs activity concentration of medicinal plants was performed using a high-resolution gamma-ray spectrometer with HpGe detector. Total committed effective dose value due to ingestion was determined as 55.04 μSv y−1 for these medicinal plants and has no risk to public health [40].
\nA study to analyze natural radioactivity level contents in Nigeria and China and a typical radioactive substance in tiles manufactured in Nigeria and tiles imported from China were evaluated using gamma-shaft spectroscopy. High purity germanium identifier was used to check the combinations of a couple of radioisotopes present in 17 trial of various tiles from Nigeria and China. The mean estimation of annual viable gamma dosages and the lifetime dangers to procure in this examination is not as much as that of the worldwide reference estimation of 370 Bq/kg for the two sorts of tiles [41].
\nAnother place in Nigeria studied building material purpose, which evaluated the activity concentration of natural radionuclides (226Ra, 232Th, and 40K) for fifteen (15) different brands of tile samples, is used for building purposes in Nigeria. The tile samples were analyzed using high purity germanium gamma detector. The deliberate centralizations of these radioactive materials were related with different past outcomes got from comparable tile materials utilized in different nations and observed to be in great concurrence with the global standard, and be that as it may, the tiles are suggested for adornment purposes in Nigeria [42].
\nA research in Amman calculated hazard indices and annual effective dose due to terrestrial radioactivity in the urban areas of south Amman. The extricated qualities are, by and large, tantamount to the relating ones acquired from different locales in Jordan and different nations and they all fall inside the normal overall reaches. Consequently, the foundation in these regions is actually equivalent to the esteem run of the mill of the upper piece of the Earth’s outside layer. Hence, all the samples investigated can be considered as safe materials for use in building constructions [43].
\nThe radioactivity groupings of 226Ra, 232Th, and 40K in 24 tests of normal and made building materials ordinarily utilized in Bangladesh were estimated utilizing HPGe gamma-beam spectrometer. Outcomes were contrasted and the world normal and furthermore with the detailed information. The radium equal action, the assimilated portion rate, yearly successful portion, outer and inside peril records, gamma file, alpha file, yearly gonadal portion equal, and overabundance lifetime malignancy chance were additionally assessed to assess the potential radiation dangers related with these building materials.
\nAll models under investigation were seen to be inside the recommended prosperity limit and don’t speak to any essential radiation risks. This examination can be used as a sort of viewpoint for more expansive examinations of a comparable subject in future [44].
\nThe radiological risk from building stone interfaces in Jordanian houses was determined depending on gamma-ray spectrometric techniques. Building stone samples collected from seven types mostly used in Jordanian houses have been analyzed for the naturally occurring radioactive radionuclides. Moreover, different radiological hazardous parameters (absorbed dose, annual effective dose equivalent, AGDE, ELCR, and AUI) were calculated. The results were lower than those of published world average values. Also, the obtained values were comparable with the presented data of other building materials used in Jordan [45].
\nTwo researches in 2017, first one is Evaluation of Natural Radioactivity and its Radiation Hazards in Some Building and Decorative Materials in Iraq, 29 examples of various kinds of building materials, for example, blocks, bond, earthenware, rock, marble, paint, mortar, sand, and soil were examined by a gamma spectrometer dependent on HPGe locator. The outcomes demonstrated that all the building materials in Iraq are sheltered with the exception of the materials that utilized as improving materials that must be directed [46].
\nThe second one is in north focal of Nigeria; measurement of the radiation portion dispersion is critical in surveying the wellbeing hazard a populace and fill in as a kind of perspective in archiving changes to ecological radioactivity in soil because of man-made exercises. The mean assimilated portion rate, yearly successful portion, and gamma radiation record assessed were 66.2 nGyh−1, 81.2 μSvy−1, and 1.05 individually which are higher than as far as possible for ordinary foundation radiation. In this manner, it is argued that individuals living in these areas might be presented to higher radiation [47].
\nThere are numerous examinations in Turkey about radioactivity levels and malignancy hazard. Turkey, particularly its northern piece, was one of the nations which were defiled by the Chernobyl mishap. In the Northeastern area of Turkey, there was a city named Rize, which was intensely affected by the Chernobyl atomic mishap.
\nThe action convergences of characteristic (226Ra, 232Th, and 40K) and artificial (137Cs) were estimations in soil tests gathered from 132 distinct focuses in Rize territory of Turkey utilizing gamma spectrometry with HPGe identifier. The open-air assimilated portion rates (D) because of earthbound gamma rays for soil have been determined due to agrarian zone and lived in the encompassing. It is essential to decide foundation radiation level with the end goal to assess the wellbeing dangers.
\nYearly viable gamma dosages and the presence dangers of disease were higher than the world’s normal. Besides contrast with the World’s normal, the existence time danger of malignancy is multiplied for a large portion of the territories [48].
\nIn Egypt, south Sinai granite is generally utilized in the development of homes as a building material. It contains the common radionuclides, 238U and 232Th, and their descendants together with 40K. This guarantees the significance of the evaluation of radiation levels and the related radiological dangers to which the populace may be uncovered. Gamma shaft spectra of standard radioactivity from the 238U and 232Th game-plan and from 40K of eight (tending to 40 gathered models) shake tests collected from Saint Katherine district, South Sinai, Egypt, had been assessed utilizing a gamma-column spectrometer with HPGe identifier. From the exploratory and computational work on normal radioactivity of Egyptian shake tests, we can complete the going with:
\nFirst, the region from where they collected the granite samples, South Sinai Governorate, Egypt contains 238U, 232Th, and 40K radionuclides with obsessions higher, comparable and lower than beyond what many would consider possible. Second, the radium tantamount activity is not actually beyond what many would consider possible. Thirdly, the danger lists, the dimension lists, and the actors use lists that are not exactly the world set criteria. Fourth, the Clark esteem is equivalent to around five which implies that district from where they took the rock tests isn’t financial for uranium mining and extraction [49].
\nSouthwestern of Nigeria (226Ra, 232Th, and 40K) and artificial (137Cs) were measured using (HPGe) detector (Canberra Industries Inc.). The outdoor absorbed dose rates in the air at about 1.0 m height were estimated from the activity concentrations and dose rate conversion factors for the radionuclides. The annual outdoor effective dose equivalent rates were also estimated for urban and rural areas of the state using the calculated absorbed dose rates in air. The results showed that area named (Igbeti and Eruwa) soils contain the highest level of natural radioactivity, while Egbeda soil contains the lowest level. The study showed that healthy burden caused by natural background radiation from soils on inhabitant area of study is generally low and carried insignificant radiation hazard except for two locations (Igbeti and Eruwa) [50].
\nA second study in Malaysia 2013, the radiation survey of the ambient environment was conducted using two gamma detectors, and the measurement results were used in the computation of the mean external radiation dose rate, mean-weighted dose rate, and annual effective dose, and also, the mean lifetime dose and lifetime cancer risk for each person living in the area with an average lifetime (70 years). Two strategies have been utilized to assess outer exposures in this examination. The first was a provoke estimation of outside gamma segment rates.
\nThe observation was taken at 497 zones in the Kluang District at 1 m above the ground utilizing two NaI-based gamma locators. The second system depended upon surveyed action revolves around soil tests and the gamma divide (Dc) from the gatherings of 238U, 232Th, and 40K. The advancement groupings of 226Ra, 232Th, and 40K in soil were acquired by utilizing the HPGe gamma spectrometer. The advancement fixations decided for 57 soil tests. The rationale for affirmation of the gamma segment rates from the fixations was gotten a handle on from United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) 2000 [51].
\nThe fundamental goal of this examination is to decide the action centralizations of primordial radionuclides in soil tests gathered from various of studying locale areas in India such as Ramanagara, Tumkur, and Karnataka districts, using gamma bar spectrometry and besides the radiological dangers records identified with based on soil tests. The radiological hazard files of the common radioactivity have been determined and contrasted and the globally affirmed qualities. The convergence of these radionuclides with various sizes and depth of the dirt examples was contemplated. They were found to pursue [52]:
\nThe 232Th and 40K action focus was seen to be marginally higher than the world normal values reported by UNSCEAR (2000). The normal 226Ra fixation in soil tests of the contemplated zone was observed to be like the world normal.
\nThe assessed normal action grouping of 226Ra, 232Th, and 40K in soil tests of those contemplated zones observed to be higher than the Indian normal.
\nResults acquired had demonstrated radiological dangers, for example, gamma list, radium equal movement, external peril record, and indoor risk list are well inside the world normal esteem. At last, it is presumed that the radiation discharged from the radionuclides present in the dirt of the examination zone doesn’t represent any radiological wellbeing risk to the general population of the zone.
\nThe normal indoor and open-air ingested portion rate for the dirt examples of investigation zone were marginally higher than the world normal estimations of 75 nGy h−1 for indoor what’s more, 59 nGy h−1 for open air.
\nResults show that ordinary indoor, outdoors amazing part, and a total yearly convincing bit in view of trademark radioactivity of soil tests is lower than the typical national and world endorsed estimation of 1 mSv y−1.
\nMovement assembly of primordial radionuclides increases with an addition in grain gauge.
\nInformation procured in this examination will fill in as a benchmark for looking over the radiation presentation of the inhabitants.
\nThis section manages gamma foundation radiation which uncovered with two noteworthy normal sources; earthly gamma rays and astronomical rays.
\nRecent studies in building materials, medical plants, building purposes, some vegetables and fruits commonly used in markets, and different soil samples in various countries in the world. The measurements of gamma background radiation differ according to the purpose. Each type of detectors is explained which are: radiographic films (scintillation detector), TLD detector (thermoluminescence detector), diode detector, and HPGe detector. The mechanism for each detector is provided with recently applied researches for the past 10 years, focusing on used gamma background radiations measurements.
\nThe author expresses a deep sense of gratitude to Kufa University, Faculty of Science, for providing the scientific support to do this work. The author is grateful to Dr. Basim Almayahi, University of Kufa (basimnajaf@yahoo.com), for assisting throughout conducting the present chapter.
\nThe author declares that she has no conflicts of interest.
As described by the Centers for Disease Control and Prevention [1, 2], intimate partner violence (IPV; also referred to as dating abuse, dating aggression, or dating violence in the adolescent development literature) consists of aggressive or abusive behaviors expressed or experienced within romantic relationships. Such behaviors can be expressed/experienced through means of psychological (i.e., verbal or emotional), physical, and/or sexual abuse. The co-occurrence and progression of these various forms of abuse is well-documented in the literature [3, 4, 5, 6, 7, 8, 9, 10, 11]. Using a biopsychosocial framework (see Figure 1), we argue that sexual abuse must be studied as an integration with other forms of abuse (see Figure 2) and potentially as a development from other forms of aggression, particularly psychological aggression (see Figure 3). Understanding the integration of these behaviors will be beneficial for researchers, practitioners, and interventionists in the attempts to reach survivors of sexual abuse.
An integration of abuse via a biopsychosocial framework.
An integrative illustration of sexual, physical, psychological, and cyber abuse in adolescent and young adult relationships.
An illustration of the progression from psychological/cyber abuse to physical and sexual abuse.
Moreover, to prevent a behavior, it is also best to address it during its origin. The CDC quote noted above implies that without intervention or preventive methods, the effects and continuation of unhealthy behaviors can progress over time. Surprisingly, adolescent romantic relationships were once deemed as shallow and frivolous given the transient nature of these relationships, particularly among early adolescents [12]. However, research within the past two decades argue that the formation of romantic relationships is critical to adolescent development [12, 13]. For instance, dating partners become a critical source for identity development during adolescence [14, 15, 16]. Data from the National Longitudinal Study of Adolescent Health (Add Health) indicated that 55% of adolescents reported to have been in a romantic relationship. Also, from this dataset, 69% of males and 76% of females indicated to have been romantically involved within the 18 months prior to data collection [17]. Additionally, romantic experiences during adolescence can influence well-being and later romantic experiences during young adulthood [18, 19, 20]. Such is also the case for adolescents who experience some form of dating violence/IPV in their romantic relationships. The view that the formation of romantic relationships plays an insignificant role on adolescent development can be dismissed for the additional reason that many adolescents who are romantically involved experience abuse in their relationships [2]. Notably, many individuals first experiences of dating violence happen before the age of 18 making youth and young adulthood a critical time for addressing and preventing this public health concern [2, 21, 22, 23]. Studies have also shown that the perpetration and victimization of IPV behaviors can extend beyond adolescence up until young adulthood [2, 10, 21, 22, 24, 25, 26].
Rates of experiencing some form of IPV in the United States (USA) are approximately 25% for women and 10% for men. Also, approximately 11 million women and five million men experienced some type of IPV before the age of 18 [1]. Furthermore, over three million Canadians aged 15 and older reported to have been victimized by psychological, physical, and/or sexual IPV within the past five years [27]. Rates of experiencing and/or perpetrating specific forms of IPV across various parts of the globe are reported below within their respective sections. Consequences from involvement in an abusive relationship among adolescents and young adults include reports of depression, anxiety, suicide ideation, interpersonal problems, and posttraumatic stress disorder [2, 28, 29, 30, 31, 32]. Reports of IPV within these populations have also been associated with unhealthy behaviors ranging from substance use, unhealthy weight control behaviors, sexual risk behaviors, and teenage pregnancy [2, 31, 33, 34, 35, 36, 37]. Lastly, victimization from teen dating violence is related to antisocial behaviors (e.g., lying, stealing, bullying, hitting, or engaging in criminal activities) [2, 30, 31, 38, 39].
Additionally, the social and digital age of our current times has given rise to a new form of psychological dating aggression expressed/experienced through means of technology. We term such behaviors as cyber-digital relationship abuse (CDRA). CDRA is also considered to be a new form of psychological dating aggression [40] that may also co-occur and even progress to physical and/or sexual abuse [41].
In the present chapter, we argue that sexual abuse ought not to be examined in isolation as such behaviors may intertwine with psychological and physical abuse. We also argue that both sexual and physical abuse can progress from psychological abuse. Additionally, we focus on the prevalence of these behaviors during the period of adolescence and young adulthood as this is when abusive behaviors within romantic relationships may first originate. We later argue on the implications for researchers, practitioners, interventionists, and high school and college counselors for examining these various forms of abuse from an integrative approach.
Defining sexual abuse has been challenging among researchers. Particularly because such behaviors can be perpetrated by a stranger, acquaintance, or romantic partner [42, 43, 44, 45]. For our purpose, sexual abuse is described as forced sexual activities/sexual contact expressed towards a romantic partner. Additionally, sexual abuse has been defined differently throughout the literature. Some researchers have defined such behaviors based on forced penetrative acts (e.g., “Using force (like hitting, holding down, or using a weapon) to make one’s partner have sex”; “unwanted penetration when a victim/survivor is unable to consent or is “unaware”, i.e., asleep or under the influence of alcohol”) ([42], p. 323; [44], p. 309). Non-physical acts expressed with the intention of forcing one’s partner to have sex is also a common form of sexual abuse (e.g., “insisting on sex when one’s partner doesn’t want to without using physical force”; “the use of non-physical, controlling, degrading, and manipulative tactics to obtain, or attempt to obtain unwanted oral, vaginal, or anal intercourse, including forced penetration and sex with objects”) ([42], p. 323; [44]). Sexual abuse has also been defined as non-penetrative sexual acts expressed physically and/or verbally (e.g., kissing or touching one’s partner sexually without their approval; “the use of manipulative, psychologically abusive tactics to keep an intimate partner in submissive positions of power; strategies include sexual degradation, non-contact unwanted sexual experiences, and reproductive and sexual control”) ([42], p. 323; [46, 47]). Other forms of sexual abuse include “exposing sexual body parts, being made to look at or participate in sexual photos or movies, harassed in a public place in a way that felt unsafe” ([46], p. 17). In summary, sexual abuse consists of aggressive behaviors expressed either physically and/or psychologically. These behaviors entail more than just rape/forced sexual intercourse and they can be expressed with the intention to control and/or intimidate one’s romantic partner. Moreover, the expression of sexual abuse via psychological and physical means further supports the notion of integrating all three types of abuse.
According to findings from the
Unlike other types of abuse, there is less co-occurrence between perpetration and victimization in reports of sexual abuse among youth and young adults. Primarily because such behaviors are generally perpetrated by men [52]. However, reports of sexual abuse expressed towards men should not be undermined. NISVS findings indicated that approximately nine million men experienced unwanted sexual contact, nonphysical unwanted sexual experiences, were forced to receive oral sex from a male or female, were forced to engage in sexual intercourse with a woman, and/or were forced to penetrate a male or female anally [46]. Furthermore, 12.5% of high school females and 3.8% of high school males were victimized by some form of sexual abuse [2].
Perpetrators of sexual abuse are more likely to report high engagement in alcohol use, high levels of delinquent behaviors, and to report more sexual partners [11]. Victims of sexual abuse are also likely to engage in risky sexual behaviors, experience teenage pregnancy, engage in risky health behaviors to lose weight (excessive use of diet pills, laxative, and excessive vomiting), and experience suicide ideation [37]. Katz et al. [5] indicated that undergraduate female students who experienced both physical and sexual abuse reported less general and sexual satisfaction in their romantic relationship.
Physical abuse consists of aggressive behaviors perpetrated with the intention to harm one’s romantic partner. Rates of experiencing physical abuse from a dating partner have ranged between 7–30% among adolescents and young adults in the USA [2, 37, 53]. Concerns relating to physical abuse are not limited to the USA, as according to the Women’s National Institute, 66.5% of Mexican adolescents reported being victims of some type of physical abuse in their relationships. Moreover, it was found that only 10% of these victims were likely to report the abuse [54]. Data collected from Spain by the Government Delegation of Gender Violence [55] revealed that adolescents under the age of 18 who were victims of physical abuse remained in such relationships for an average of 3.5 years; in some cases, relationship lasted up to eight years. Also, recently Exner-Cortens, Baker, and Craig [56] found that 11.8% of Canadian youth (grades 9 & 10) were victimized by physical aggression and that 7.3% of Canadian youth perpetrated acts of physical aggression. These findings suggest that physical abuse is a worldwide health problem among adolescents and young adults.
Rates of physical abuse among adolescents and young adults can also vary based on the severity of the aggression. Specifically, behaviors deemed as minor or moderate (e.g., throwing, grabbing, slapping, and/or twisting a partner’s fingers, arm, or hair) are more likely to be experienced/expressed relative to severe forms of aggression (e.g., choking, beating up, burning, and/or using a knife/gun on one’s partner) [44, 57]. For instance, among a sample of rural adolescents in North Carolina (13–19 years old), Foshee et al. [57] found that rates of perpetrating minor/moderate forms of physical abuse ranged between 13–21% whereas rates of perpetrating severe forms of physical abuse ranged between 5–9% across five waves of data. Among a community sample of young adults (18–25 years old), Saint-Eloi Cadely et al. [10] found that across eight waves of data, between 21–65% of participants reported to have perpetrated minor forms of physical abuse, whereas between 3–38% of participants indicated to have perpetrated severe forms of physical abuse. Furthermore, among a sample of Latinx adolescents (12–17 years old) whom all experienced physical abuse, Munoz-Rivas, Ronzon-Tirado, Redondo, & Cassinello [58] indicated that between 24–72% of adolescents were victimized by what was defined as mild forms of physical abuse (i.e., being punched or held tightly by a partner, being kicked or bitten, or having been hit or slapped) whereas only 1–2% of adolescents experienced more severe forms of aggression (i.e., being beaten, strangled, or attacked with a knife or weapon).
Importantly, many adolescents and young adults who are victims of physical abuse also report to have perpetrated such behaviors [7, 56, 59, 60]. The co-occurrence between reports of perpetration and victimization may explain the similarity in the reports of these behaviors across sexes. Although often debated, gender symmetry in physical abuse (similar reports across sexes in the perpetration of physical abuse) is largely supported in the literature [52] and is more commonly found among samples of adolescents and young adults [61]. Studies within these populations also found that at times higher rates of perpetrating physical aggression are reported by females relative to males [61, 62, 63, 64]. However, adolescent and young adult women are more likely to be injured by physical aggression [61], partially due to adolescent and young adult males being more likely to engage in more severe forms of physical aggression [29, 57, 65, 66].
The effects of physical abuse among adolescents are detrimental. For instance, adolescents who perpetrate physical abuse are more likely to exhibit externalizing and/or internalizing behaviors [31]. Victims of physical abuse are likely to engage in risky sexual behaviors (e.g., lack of condom use and having sex at a young age) [33], drop out of high school [28], and experience mental health disorders such as dissociation, posttraumatic stress, and depression [28, 29]. Even more troubling, many adolescents have trouble leaving a physically abusive relationship. This was found due to the satisfaction and commitment to the relationship, justification for the aggression as joking/playing around, and psychological coercion (e.g., feeling forced to remain in an abusive relationship) [58].
Psychological abuse (also referred to as psychological aggression or emotional abuse in the literature) is defined as “the use of verbal and non-verbal communication with the intent to harm a partner mentally or emotionally and/or exert control over a partner” [2]. Psychological abuse is by far the most prevalent form of dating violence and is estimated to effect nearly half of all adults [67] and varies across studies from 20% to over 95% among teens [68, 69, 70]. Yahner et al. [39], in a large-scale cross-sectional study of 7-12th graders from 3 states in the Northeast, found that nearly one third of their sample reported experiences of psychological abuse. More alarmingly, rates of perpetration of psychological abuse may be more prevalent at younger ages. For example, in a study of middle schoolers (grades 6–8) from four large high risk urban cities, 77% of youth reported perpetrating psychological dating abuse [71].
Psychological abuse is not only a significant health concern for U.S. youth, but is it also a worldwide problem. In an international review of teen dating violence in North America and Europe, Leen et al. [72] found similar rates of adolescent victimization internationally with reports as high as 77% of teens reporting psychological abuse in dating relationships. Additionally, similar to patterns in the USA, psychological abuse was the most prevalent form of dating violence among teens.
Current findings around gender differences in perpetration and victimization of psychological abuse among teens are mixed. In some cases, females are more likely than males to report perpetrating psychological abuse [73, 74]. These findings appear to align with earlier research that suggest that males are more likely to be victims of psychological abuse than females [44]. However, Hébert, Blais, and Lavoie [75], in a representative sample of Canadian youth, found that girls were more likely to report being victims of all forms of abuse with psychological abuse being the most prevalent. Similarly, in a recent national Canadian study, psychological abuse was more prevalent among adolescent females and non-binary youth relative to their male counterparts [56]. On the contrary, in an international review of teen dating violence Leen et al. [72] found rates of psychological abuse to be similar among boys and girls, there were no gender differences. Thus, it appears while the relationship between gender and psychological abuse remains unclear, this form of dating violence is a serious international public health concern.
There are many significant ramifications of psychological abuse in dating relationships. Consequences of psychological abuse include psychological distress, relationship anxiety, relationship deterioration, symptoms of depression and anxiety, substance use, suicidal ideation, and an increased risk of further victimization and perpetration of dating violence [69, 76, 77, 78, 79, 80]. Specifically, those who experience psychological abuse are more likely to be victims of physical abuse [81] thus perpetuating a cycle of violence and further supporting the need to integrate these behaviors.
While much attention in the IPV literature focuses on physical abuse, it is psychological abuse that may be more deleterious to mental health [69, 78]. In an 8-week study of teen dating violence among high school students, Jouriles et al. [78] found that not only does psychological abuse occur in higher frequency than other forms of violence, but it is also viewed as more unpleasant and intentionally hurtful than physical abuse. These findings are consistent with the adult literature which indicates that women view their partners’ psychological abuse as more negative and associate their distress more so to psychological abuse than physical abuse [82, 83].
Even prior to the COVID-19 pandemic, teens’ lives have been dominated by technology use and since the new millennium cell phones and text messaging have been the primary means of communication and social connectedness for teens and emerging adults [84]. In fact, young adults spend more time with technology than any other daily activity [85] and technology use mediates most young adult romantic relationships. This new means of communication has changed the way young adults interact within romantic relationships and has introduced a new form of psychological dating aggression, cyber-digital relationship abuse (CDRA). CDRA (also referred to as cyber dating abuse) [40, 41] or electronic dating violence [86] or technology assisted dating violence and abuse [87] is conceptualized as behaviors where technology serves as a tool to harass, threaten, control, and/or monitor a partner’s whereabouts through use of social media (e.g., Facebook and Twitter) and digital means (e.g., texting and e-mail) [88, 89, 90].
Prevalence rates of CDRA range across studies from 10–32% for perpetration and up to 51% for victimization [40, 41, 91]. According to the Research Triangle Institute International [92], 31% of 7th graders were victims of some form of CDRA. Smaller rates were found in a cross-sectional study using an ethnic minority sample of 6th graders, where 15% reported to have perpetrated CDRA [93]. It appears that rates of CDRA are even higher among LGB youth and young adults with 38% reporting psychological abuse via CDRA versus 10% of heterosexual youth and young adults [94]. It is important to note that CDRA is more frequent at younger ages [88] thus demonstrating the need for early prevention and intervention efforts.
As CDRA is a relatively new form of dating violence, gender differences are still being revealed. In a large-scale study of youth in the northeast ages 13–18, females reported more CDRA victimization than males [41]. Similarly, in a separate study of 9th graders, females were more likely to report experiences of CDRA [95]. In contrast, Cutbush [96] in a sample of 7th graders found that males were more likely to experience CDRA. This pattern was also found in a separate study by Cutbush [91] in which victimization was more prevalent for boys (42%) than for girls (31%). Ybarra et al. [94] reported equal rates of CDRA victimization by gender. Still other studies found no gender differences to emerge among young adults [88]. Thus, it appears that gender and age may play a unique role in the expression of CDRA and these dynamics need to be further explored. At this time, little is known about the relation between race and CDRA. In one study race was not associated with CDRA among high school students [41] and in another study, Hispanic race/ethnicity was correlated with perpetration of CDRA among middle school students [96]. Like gender, differences in rates of CDRA across race and ethnicity needs further exploration.
Similar to traditional forms of dating violence, CDRA is associated with a number of negative outcomes. For instance, CDRA was associated with depressive symptoms and anxiety among high school students [41, 97, 98]. Additionally, CDRA has been linked with lowered self-esteem and greater emotional distress [99] and is associated with personal and professional harm [94]. In an ethnically diverse sample of youth, CDRA was associated cross-sectionally with mental health and substance use, whereas longitudinal associations between CDRA and substance use were shown [100]. CDRA also increases likelihood of cyberbullying victimization and perpetration [88]. It is important to consider that comparable to patterns identified in traditional forms of IPV, there is a high rate of mutual engagement in CDRA [40, 56]. Essentially, victims and perpetrators are not always distinct from one another. In fact, findings indicated that the victimized often victimize via CDRA [87]. Therefore, prevention and intervention must be designed around conceptualizing teens as both perpetrators and victims of CDRA simultaneously.
Interestingly, as compared with other forms of abuse, CDRA may be more difficult to escape due to the permanent presence of technology whether it be the various ways to access the victim or the permanent nature of online posts. Moreover, Borrajo et al. [40] found that victims were repeatably victimized with an average of 23 times in last six months. Given the rise of COVID-19, many more relationships are being formed and maintained through technology, making it all the more imperative that youth and young adults are aware of parameters around healthy technology use and how to use technology to build a foundation of healthy relationship dynamics.
Considering the multifaceted nature of dating abuse, a multidimensional framework is critical for assessment, prevention, and intervention. We argue that the biopsychosocial model should be considered for this purpose (see Figure 1). Further we argue that a similar framework can be useful to examine the integration of various forms of abuse (see Figure 2) and the progression of abuse over time (see Figure 3).
The biopsychosocial model is a theoretical and conceptual framework that elegantly bridges the dichotomy between the social sciences and the medical sciences and considers the role of interpersonal, intrapersonal, and psychological dynamics for an individual’s health and well-being. George Engel [101, 102], the originator of the biopsychosocial model, proposes that simultaneous attention to biological, psychological, and social aspects are necessary when considering health and pathology processes (see Figure 1). The biopsychosocial model operates by way of a family systems perspective to understand the multiple reciprocal factors from various facets of human experience [103]. The biopsychosocial model can be applied to a variety of contexts without attempting to isolate a specific underlying cause of a problem, which is not only unlikely, but it is also highly improbable that a single factor is to blame. Similar to the biopsychosocial model, the integrative illustration of sexual, physical, psychological, and CDRA in adolescent and young adult relationships can work in similar ways. While sexual, physical, psychological, and CDRA can occur in isolation, as you can see indicated in the figure, they can also co-occur (see Figure 2) and even progress over time (see Figure 3). Assessing for various forms of dating violence can be complex. It is important that our prevention and intervention efforts utilize a multidimensional (biopsychosocial) integrative approach to exploring, treating, and preventing various forms of abuse collectively. Furthermore, considering the many biological (e.g., physical health, disability, and genetic vulnerabilities), psychological (e.g., mental health, coping skills, social skills, self-esteem, and attitudes/beliefs), and social relational factors (e.g., family relationships, peer relationships, culture, and discrimination) that influence or can be influenced by the development and progression of dating abuse further supports the necessity to understand IPV from a biopsychosocial lens.
The argument of examining various forms of IPV from an integrative perspective is supported by the literature indicating concurrent associations between psychological, physical, and sexual IPV. Among a sample of newlywed couples, Hammett et al. [63] found moderate to strong intercorrelations between self-reports of psychological and physical IPV among husbands and wives. The co-occurrence between psychological and physical IPV is also common among adolescents and young adult couples [7, 59, 66, 99]. Recently, Saint-Eloi Cadely et al. [9] showed concurrent associations between psychological and physical IPV at all five waves of data among a sample of young adults from ages 22–25. Saint-Eloi Cadely et al. [10] also found that young adults who perpetrated both minor and severe forms of psychological abuse over time also reported extensive use of physical IPV over time; these findings coincide with other studies indicating that the frequency and severity of psychological IPV is related to physical IPV [53, 92]. The relationship between psychological and physical abuse is also found based on reports of CDRA. Specifically, Borrajo et al. [40, 88] indicated that self-reports of CDRA victimization and perpetration were related to self-reports of interpersonal forms of psychological and physical IPV. Cohesively, these findings support the notion that physical abuse without psychological abuse is rare (see [104] for a review of the literature) which further supports the need for the integration of both forms of abuse.
White et al. [11] previously called for researchers to investigate the co-emergence between physical and sexual abuse. Additionally, Katz et al. [5] argued that the co-victimization of physical and sexual abuse from a dating partner (i.e., “experiencing both physical violence and unwanted sexual contact from one’s dating partner, but not necessarily during the same event”, p. 963) ought to be treated distinctly from other forms of abuse standing alone. We argue that psychological abuse ought to be included in this co-emergence of abusive behaviors. Although understudied, the literature hints on a co-occurrence across all three forms of abuse. Within the
Historically, much of the literature has focused on various forms of abuse as if they are truly distinct and occur in isolation from other forms of abuse. However, the research documents that this is not the case and that various forms of abuse often co-occur with other forms of abuse [5, 11, 104]. The co-occurrence literature across these various forms of IPV also hints on a possible progression from psychological to physical and/or sexual IPV.
Although the detrimental effects of psychological IPV should not be undermined, such behaviors are often dismissed as normative behaviors among couples (particularly minor forms of psychological IPV) [107]. Thus, it can be found easier for perpetrators to initiate psychological forms of IPV before progressing to other forms of abuse. Previous cross-sectional studies hinted on the possible progression from psychological to physical IPV among adolescents and young adults [3, 4, 59, 66, 99]. Longitudinal studies more strongly support this notion by indicating a relationship between early reports of psychological abuse and later reports of physical abuse [6, 7, 8]. More recently, stronger empirical tests using longitudinal data support the progression from psychological to physical abuse with more confidence. For instance, using cross-lag analysis among a sample of young adults (ages 22–25), Saint-Eloi Cadely et al. [9] compared the associations between early and later reports of psychological and physical IPV in one model across five waves of data. Specifically, the model controlled for the direction of early reports of psychological IPV predicting later reports of physical IPV in addition to early reports of physical IPV predicting later reports of psychological IPV across waves. Results showed that early reports of psychological IPV consistently predicted later reports of physical IPV, whereas the opposite direction either was shown to be non-significant or to work in the opposite direction. Moreover, among a sample of young adult couples (Men,
Given the connections between psychological abuse as a segue to later physical abuse among adolescents and young adults, it stands to reason that CDRA may also serve as a pathway to physical forms of abuse should such behaviors be regarded as a new form of psychological abuse. However, this longitudinal pathway along with the longitudinal association from psychological to sexual forms of IPV remains underdeveloped. Similar to physical IPV, sexual IPV is also at times perpetrated with the intention to control one’s partner [104]. The use of control in an abusive relationship is a psychologically aggressive act. Abusive partners commonly turn to physical acts of violence as an additional means to control their partner when psychological means are not perceived as enough [82, 109]. Under this notion, it is highly plausible that aggressive partners may turn to sexual abuse for the same purpose. Therefore, it is imperative to further examine the progression from CDRA to physical and sexual aggression and from psychological to sexual abuse. Furthermore, given the evidence supporting the continuation of psychological, physical, and sexual abuse from adolescence to young adulthood [10, 24, 25, 26], the progression between these various forms of IPV ought to be examined during this transitional period.
The foundations for healthy adult romantic relationships begin with a youth’s first romantic formation. As we have demonstrated in this chapter, it is clear from the literature that different forms of abuse: sexual, physical, psychological, and CDRA, rarely occur in isolation. Moreover, milder forms of abuse have the potential to develop into more severe forms of abuse over time [66, 99]. Additionally, there is a high likelihood of mutual engagement in the various forms of abuse among teens where there is not always a clear victim and perpetrator but rather both partners have been victimized and perpetrated against [69, 80, 88].
Given the high prevalence of IPV among teens, and the likelihood of mutual engagement, it is all the more imperative that prevention and intervention efforts start early and provide a multidimensional framework inclusive of various forms of dating violence and geared towards both perpetration and victimization in the same curriculum. As we design our prevention and intervention efforts, attitudes towards violence may be an important factor to consider as a potential pathway for prevention and intervention as they have been shown to predict involvement in both victimization and perpetration of dating violence [80, 110]. Moreover, understanding the developmental pathways and integrative nature of dating abuse is crucial as we work towards preparing and supporting a foundation for healthy adult relationships. Practitioners, interventionists, high school and college counselors, and support staff should provide education around healthy relationship skill building including the development of conflict management/resolution skills, communication training, emotion regulation and de-escalation strategies, and healthy technology use. Assessment of violence should utilize a multidimensional biopsychosocial approach that includes checkups over time to look out for the progression of violence. While a teen may be experiencing only one form of violence at a cross section in time it would be beneficial to be aware of the potential co-occurrence and/or progression of violence over time. Future research must examine the co-occurrence and progression of sexual, psychological, physical, and CDRA longitudinally to better understand the causal nature and interplay among the various forms of aggression in efforts to refine and improve prevention and intervention efforts.
Targeting prevention and intervention efforts towards youth is imperative as IPV is most prevalent among youth and declines with age [111]. As youth and young adults begin to form their patterns of interaction that will then influence their later adult romantic relationships, the development of healthy relationship skills that can potentially prevent experiences of sexual, physical, and psychological abuse, and CDRA in adolescent and young adult romantic relationships is critical.
IntechOpen Compacts provide a mid-length publishing format which bridges the gap between journal articles, book chapters and monographs, and cover content across all scientific disciplines. Compacts are the preferred publishing option for brief research reports on new topics, in-depth case studies, dissertations, or essays exploring new ideas, issues or broader topics on the research subject.
",metaTitle:"IntechOpen Compacts",metaDescription:"IntechOpen Compacts present a mid-length publishing format which bridges the gap between journal articles, book chapters, and monographs and covers content across all scientific disciplines.",metaKeywords:null,canonicalURL:"/page/compacts",contentRaw:'[{"type":"htmlEditorComponent","content":"Without sacrificing the quality of carefully edited and produced peer-reviewed content, Compacts are published as part of IntechOpen’s book collection but on a faster schedule, typically 4-6 weeks after acceptance. With an average of 132,000 visitors per week, publishing in Compacts not only guarantees high visibility but also facilitates international content sharing. As a fully Open Access publisher, the utilization of a CC BY NC 4.0 license means that other researchers will never have to pay permission fees and can adapt, use, and further build upon the material published in Compacts, eliminating any barriers to the further development of scientific research.
\\n\\nCOMPACTS-SHORT FORM MONOGRAPH
\\n\\nCOST
\\n\\n4,000 GBP Compacts Monograph - Short Form
\\n\\nThe final price will depend on the volume of the publication and includes project management, editorial and peer-review services, technical editing, language copyediting, cover design, book layout, book promotion and ISBN assignment.
\\n\\n*The price does not include Value-Added Tax (VAT). Residents of European Union countries need to add VAT based on the specific rate applicable in their country of residence. Institutions and companies registered as VAT taxable entities in their own EU member state will not pay VAT by providing us with their VAT registration number. This is made possible by the EU reverse charge method.
\\n\\nOptional Services
\\n\\nIntechOpen has collaborated with Enago, through its sister company, Ulatus – one of the world’s leading providers of book translation services. The services are designed to convey the essence of your work seamlessly to readers from across the globe in their own language. Enago’s expert translators incorporate cultural nuances in translations to make the content relevant for local audiences while retaining the original meaning and style. With a high degree of linguistic and subject expertise, Enago translators are equipped to handle all complex and multiple overlapping themes encompassed in a single book to deliver a superior quality of translation.
\\n\\nIntechOpen Authors that wish to use this service will receive a 20% discount on all translation work. For more information or a quote, please visit: https://www.enago.com/intech.
\\n\\nFUNDING
\\n\\nWe feel that financial barriers should never prevent researchers from publishing their research. Please consult our Open Access Funding page to explore funding opportunities and learn more about how you can finance your IntechOpen publication.
\\n\\nBENEFITS
\\n\\nPUBLISHING PROCESS STEPS
\\n\\nSee a complete overview and description of the steps involved in the publishing process here.
\\n\\nSEND YOUR PROPOSAL
\\n\\nIf you are interested in publishing your book with IntechOpen, please submit your book proposal by completing the Publishing Proposal Form.
\\n\\nNot sure if this is the right option for you? Please refer back to the main Publish with IntechOpen page or feel free to contact us directly at book.department@intechopen.com
\\n"}]'},components:[{type:"htmlEditorComponent",content:'Without sacrificing the quality of carefully edited and produced peer-reviewed content, Compacts are published as part of IntechOpen’s book collection but on a faster schedule, typically 4-6 weeks after acceptance. With an average of 132,000 visitors per week, publishing in Compacts not only guarantees high visibility but also facilitates international content sharing. As a fully Open Access publisher, the utilization of a CC BY NC 4.0 license means that other researchers will never have to pay permission fees and can adapt, use, and further build upon the material published in Compacts, eliminating any barriers to the further development of scientific research.
\n\nCOMPACTS-SHORT FORM MONOGRAPH
\n\nCOST
\n\n4,000 GBP Compacts Monograph - Short Form
\n\nThe final price will depend on the volume of the publication and includes project management, editorial and peer-review services, technical editing, language copyediting, cover design, book layout, book promotion and ISBN assignment.
\n\n*The price does not include Value-Added Tax (VAT). Residents of European Union countries need to add VAT based on the specific rate applicable in their country of residence. Institutions and companies registered as VAT taxable entities in their own EU member state will not pay VAT by providing us with their VAT registration number. This is made possible by the EU reverse charge method.
\n\nOptional Services
\n\nIntechOpen has collaborated with Enago, through its sister company, Ulatus – one of the world’s leading providers of book translation services. The services are designed to convey the essence of your work seamlessly to readers from across the globe in their own language. Enago’s expert translators incorporate cultural nuances in translations to make the content relevant for local audiences while retaining the original meaning and style. With a high degree of linguistic and subject expertise, Enago translators are equipped to handle all complex and multiple overlapping themes encompassed in a single book to deliver a superior quality of translation.
\n\nIntechOpen Authors that wish to use this service will receive a 20% discount on all translation work. For more information or a quote, please visit: https://www.enago.com/intech.
\n\nFUNDING
\n\nWe feel that financial barriers should never prevent researchers from publishing their research. Please consult our Open Access Funding page to explore funding opportunities and learn more about how you can finance your IntechOpen publication.
\n\nBENEFITS
\n\nPUBLISHING PROCESS STEPS
\n\nSee a complete overview and description of the steps involved in the publishing process here.
\n\nSEND YOUR PROPOSAL
\n\nIf you are interested in publishing your book with IntechOpen, please submit your book proposal by completing the Publishing Proposal Form.
\n\nNot sure if this is the right option for you? Please refer back to the main Publish with IntechOpen page or feel free to contact us directly at book.department@intechopen.com
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. In the Engineering side, Digital Signal Processing, Computer Architecture, Electronics Devices, Digital Filtering and Engineering Management.\nApart from his Academic Interest and activities he loves sport especially, Cricket, Football, Snooker and Squash. He plays cricket for Esbjerg city in the second division team as an opener wicket keeper batsman. He is a very good player of squash but has not played squash since his arrival in Denmark.",institutionString:null,institution:null},{id:"611",title:"Prof.",name:"T",middleName:null,surname:"Nagarajan",slug:"t-nagarajan",fullName:"T Nagarajan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universiti Teknologi Petronas",country:{name:"Malaysia"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:6675},{group:"region",caption:"Middle and South America",value:2,count:5955},{group:"region",caption:"Africa",value:3,count:2459},{group:"region",caption:"Asia",value:4,count:12718},{group:"region",caption:"Australia and Oceania",value:5,count:1017},{group:"region",caption:"Europe",value:6,count:17720}],offset:12,limit:12,total:134177},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{hasNoEditors:"0",sort:"dateEndThirdStepPublish"},books:[{type:"book",id:"11369",title:"RNA Viruses",subtitle:null,isOpenForSubmission:!0,hash:"52f8a3a1486912beae40b34ac557fed3",slug:null,bookSignature:"Ph.D. Yogendra Shah",coverURL:"https://cdn.intechopen.com/books/images_new/11369.jpg",editedByType:null,editors:[{id:"278914",title:"Ph.D.",name:"Yogendra",surname:"Shah",slug:"yogendra-shah",fullName:"Yogendra Shah"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11610",title:"New Insights in Herbicide Science",subtitle:null,isOpenForSubmission:!0,hash:"eb3830b8176caf3d1fd52c32313c5168",slug:null,bookSignature:"Ph.D. Kassio Ferreira Mendes",coverURL:"https://cdn.intechopen.com/books/images_new/11610.jpg",editedByType:null,editors:[{id:"197720",title:"Ph.D.",name:"Kassio",surname:"Ferreira Mendes",slug:"kassio-ferreira-mendes",fullName:"Kassio Ferreira Mendes"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11027",title:"Basics of Hypoglycemia",subtitle:null,isOpenForSubmission:!0,hash:"98ebc1e36d02be82c204b8fd5d24f97a",slug:null,bookSignature:"Dr. Alok Raghav",coverURL:"https://cdn.intechopen.com/books/images_new/11027.jpg",editedByType:null,editors:[{id:"334465",title:"Dr.",name:"Alok",surname:"Raghav",slug:"alok-raghav",fullName:"Alok Raghav"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11124",title:"Next-Generation Textiles",subtitle:null,isOpenForSubmission:!0,hash:"093f9e26bb829b8d414d13626aea1086",slug:null,bookSignature:"Dr. Hassan Ibrahim",coverURL:"https://cdn.intechopen.com/books/images_new/11124.jpg",editedByType:null,editors:[{id:"90645",title:"Dr.",name:"Hassan",surname:"Ibrahim",slug:"hassan-ibrahim",fullName:"Hassan Ibrahim"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11561",title:"Zeolite From Wastes - New Perspectives on Innovative Resources and Their Valorization Process",subtitle:null,isOpenForSubmission:!0,hash:"3ed0dfd842de9cd1143212415903e6ad",slug:null,bookSignature:"Dr. Claudia Belviso",coverURL:"https://cdn.intechopen.com/books/images_new/11561.jpg",editedByType:null,editors:[{id:"61457",title:"Dr.",name:"Claudia",surname:"Belviso",slug:"claudia-belviso",fullName:"Claudia Belviso"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11709",title:"Type 1 Diabetes Mellitus",subtitle:null,isOpenForSubmission:!0,hash:"cc0e61f864a2a8a9595f4975ce301f70",slug:null,bookSignature:"Dr. Shilpa Mehta and Dr. Resmy Palliyil Gopi",coverURL:"https://cdn.intechopen.com/books/images_new/11709.jpg",editedByType:null,editors:[{id:"342545",title:"Dr.",name:"Shilpa",surname:"Mehta",slug:"shilpa-mehta",fullName:"Shilpa Mehta"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11881",title:"Ventricular Assist Devices - Advances and Applications in Heart Failure",subtitle:null,isOpenForSubmission:!0,hash:"4c5136113dda974a93f03ba12724b31b",slug:null,bookSignature:"Associate Prof. Enkhsaikhan Purevjav, Dr. Hugo R. Martinez, Dr. Mohammed Absi, Dr. Jeffrey Allen Towbin and Dr. Umar Boston",coverURL:"https://cdn.intechopen.com/books/images_new/11881.jpg",editedByType:null,editors:[{id:"231585",title:"Associate Prof.",name:"Enkhsaikhan",surname:"Purevjav",slug:"enkhsaikhan-purevjav",fullName:"Enkhsaikhan Purevjav"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11669",title:"Fatty Acids - Recent Advances",subtitle:null,isOpenForSubmission:!0,hash:"9117bd12dc904ced43404e3383b6591a",slug:null,bookSignature:"Assistant Prof. Erik Froyen",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",editedByType:null,editors:[{id:"415310",title:"Assistant Prof.",name:"Erik",surname:"Froyen",slug:"erik-froyen",fullName:"Erik Froyen"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11800",title:"Cyanobacteria - Recent Advances and New Perspectives",subtitle:null,isOpenForSubmission:!0,hash:"645b037b086ec8c36af614326dce9804",slug:null,bookSignature:"Dr. Archana Tiwari",coverURL:"https://cdn.intechopen.com/books/images_new/11800.jpg",editedByType:null,editors:[{id:"186791",title:"Dr.",name:"Archana",surname:"Tiwari",slug:"archana-tiwari",fullName:"Archana Tiwari"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11922",title:"Watermarking - Recent Advances, New Perspectives and Applications",subtitle:null,isOpenForSubmission:!0,hash:"9843dc1d810407088ed9eef10768a64b",slug:null,bookSignature:"Prof. Joceli Mayer",coverURL:"https://cdn.intechopen.com/books/images_new/11922.jpg",editedByType:null,editors:[{id:"110638",title:"Prof.",name:"Joceli",surname:"Mayer",slug:"joceli-mayer",fullName:"Joceli Mayer"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11762",title:"Characteristics and Applications of Boron",subtitle:null,isOpenForSubmission:!0,hash:"611776f7f3cc9951a8956d2e3d535a8e",slug:null,bookSignature:"Associate Prof. Chatchawal Wongchoosuk",coverURL:"https://cdn.intechopen.com/books/images_new/11762.jpg",editedByType:null,editors:[{id:"34521",title:"Associate Prof.",name:"Chatchawal",surname:"Wongchoosuk",slug:"chatchawal-wongchoosuk",fullName:"Chatchawal Wongchoosuk"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11910",title:"Frontiers in Voltammetry",subtitle:null,isOpenForSubmission:!0,hash:"fc53a7599a61ed04a0672a7bca81e9c2",slug:null,bookSignature:"Dr. Rajendrachari Shashanka, Dr. Kiran Kenchappa Somashekharappa, Dr. Sharath Peramenahalli Chikkegouda and Dr. Shamanth Vasanth",coverURL:"https://cdn.intechopen.com/books/images_new/11910.jpg",editedByType:null,editors:[{id:"246025",title:"Dr.",name:"Shashanka",surname:"Rajendrachari",slug:"shashanka-rajendrachari",fullName:"Shashanka Rajendrachari"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:38},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:13},{group:"topic",caption:"Business, Management and Economics",value:7,count:7},{group:"topic",caption:"Chemistry",value:8,count:23},{group:"topic",caption:"Computer and Information Science",value:9,count:24},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:15},{group:"topic",caption:"Engineering",value:11,count:65},{group:"topic",caption:"Environmental Sciences",value:12,count:10},{group:"topic",caption:"Immunology and Microbiology",value:13,count:16},{group:"topic",caption:"Materials Science",value:14,count:25},{group:"topic",caption:"Mathematics",value:15,count:11},{group:"topic",caption:"Medicine",value:16,count:116},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:6},{group:"topic",caption:"Neuroscience",value:18,count:4},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:9},{group:"topic",caption:"Physics",value:20,count:9},{group:"topic",caption:"Psychology",value:21,count:10},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:9},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:4}],offset:12,limit:12,total:417},popularBooks:{featuredBooks:[{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10195",title:"Serotonin and the CNS",subtitle:"New Developments in Pharmacology and Therapeutics",isOpenForSubmission:!1,hash:"7ed9d96da98233a885bd2869a8056c36",slug:"serotonin-and-the-cns-new-developments-in-pharmacology-and-therapeutics",bookSignature:"Berend Olivier",coverURL:"https://cdn.intechopen.com/books/images_new/10195.jpg",editors:[{id:"71579",title:"Prof.",name:"Berend",middleName:null,surname:"Olivier",slug:"berend-olivier",fullName:"Berend Olivier"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11012",title:"Radiopharmaceuticals",subtitle:"Current Research for Better Diagnosis and Therapy",isOpenForSubmission:!1,hash:"f9046d6f96148b285e776f384991120d",slug:"radiopharmaceuticals-current-research-for-better-diagnosis-and-therapy",bookSignature:"Farid A. Badria",coverURL:"https://cdn.intechopen.com/books/images_new/11012.jpg",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9974",title:"E-Learning and Digital Education in the Twenty-First Century",subtitle:null,isOpenForSubmission:!1,hash:"88b58d66e975df20425fc1dfd22d53aa",slug:"e-learning-and-digital-education-in-the-twenty-first-century",bookSignature:"M. Mahruf C. Shohel",coverURL:"https://cdn.intechopen.com/books/images_new/9974.jpg",editors:[{id:"94099",title:"Dr.",name:"M. Mahruf C.",middleName:null,surname:"Shohel",slug:"m.-mahruf-c.-shohel",fullName:"M. Mahruf C. Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4431},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1677,editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10195",title:"Serotonin and the CNS",subtitle:"New Developments in Pharmacology and Therapeutics",isOpenForSubmission:!1,hash:"7ed9d96da98233a885bd2869a8056c36",slug:"serotonin-and-the-cns-new-developments-in-pharmacology-and-therapeutics",bookSignature:"Berend Olivier",coverURL:"https://cdn.intechopen.com/books/images_new/10195.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1337,editors:[{id:"71579",title:"Prof.",name:"Berend",middleName:null,surname:"Olivier",slug:"berend-olivier",fullName:"Berend Olivier"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1309,editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:847,editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",publishedDate:"June 15th 2022",numberOfDownloads:2273,editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:591,editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:515,editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:413,editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",publishedDate:"June 8th 2022",numberOfDownloads:2194,editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:341,editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"11043",title:"Endometriosis",subtitle:"Recent Advances, New Perspectives and Treatments",isOpenForSubmission:!1,hash:"7baf1c70b11d41400bb9302ae9411ca4",slug:"endometriosis-recent-advances-new-perspectives-and-treatments",bookSignature:"Giovana Ap. Gonçalves",coverURL:"https://cdn.intechopen.com/books/images_new/11043.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"185930",title:"Associate Prof.",name:"Giovana",middleName:null,surname:"Gonçalves",slug:"giovana-goncalves",fullName:"Giovana Gonçalves"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10536",title:"Campylobacter",subtitle:null,isOpenForSubmission:!1,hash:"c4b132b741dd0a2ed539b824ab63965f",slug:"campylobacter",bookSignature:"Guillermo Tellez-Isaias and Saeed El-Ashram",coverURL:"https://cdn.intechopen.com/books/images_new/10536.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"73465",title:"Dr.",name:"Guillermo",middleName:null,surname:"Téllez",slug:"guillermo-tellez",fullName:"Guillermo Téllez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10798",title:"Starch",subtitle:"Evolution and Recent Advances",isOpenForSubmission:!1,hash:"f197f6062c1574a9a90e50a369271bcf",slug:"starch-evolution-and-recent-advances",bookSignature:"Martins Ochubiojo Emeje",coverURL:"https://cdn.intechopen.com/books/images_new/10798.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11083",title:"Hazardous Waste Management",subtitle:null,isOpenForSubmission:!1,hash:"d553bd4f6f1c4b115ca69bd19faac7dc",slug:"hazardous-waste-management",bookSignature:"Rajesh Banu Jeyakumar, Kavitha Sankarapandian and Yukesh Kannah Ravi",coverURL:"https://cdn.intechopen.com/books/images_new/11083.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"218539",title:"Dr.",name:"Rajesh Banu",middleName:null,surname:"Jeyakumar",slug:"rajesh-banu-jeyakumar",fullName:"Rajesh Banu Jeyakumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10848",title:"Tribology of Machine Elements",subtitle:"Fundamentals and Applications",isOpenForSubmission:!1,hash:"3c4ca4c4692ca8d4fa749b4ae81ec1fa",slug:"tribology-of-machine-elements-fundamentals-and-applications",bookSignature:"Giuseppe Pintaude, Tiago Cousseau and Anna Rudawska",coverURL:"https://cdn.intechopen.com/books/images_new/10848.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"18347",title:"Prof.",name:"Giuseppe",middleName:null,surname:"Pintaude",slug:"giuseppe-pintaude",fullName:"Giuseppe Pintaude"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10856",title:"Crude Oil",subtitle:"New Technologies and Recent Approaches",isOpenForSubmission:!1,hash:"8d0a7ca35b3de95b295dc4eab39a087e",slug:"crude-oil-new-technologies-and-recent-approaches",bookSignature:"Manar Elsayed Abdel-Raouf and Mohamed Hasan El-Keshawy",coverURL:"https://cdn.intechopen.com/books/images_new/10856.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"102626",title:"Prof.",name:"Manar",middleName:null,surname:"Elsayed Abdel-Raouf",slug:"manar-elsayed-abdel-raouf",fullName:"Manar Elsayed Abdel-Raouf"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9625",title:"Spinocerebellar Ataxia",subtitle:"Concepts, Particularities and Generalities",isOpenForSubmission:!1,hash:"365a7025fd46eb45de2549bdd9d50b98",slug:"spinocerebellar-ataxia-concepts-particularities-and-generalities",bookSignature:"Patricia Bozzetto Ambrosi",coverURL:"https://cdn.intechopen.com/books/images_new/9625.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"221787",title:"Dr.",name:"Patricia",middleName:null,surname:"Bozzetto Ambrosi",slug:"patricia-bozzetto-ambrosi",fullName:"Patricia Bozzetto Ambrosi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10905",title:"Plant Defense Mechanisms",subtitle:null,isOpenForSubmission:!1,hash:"84ad5b27dde5f01dc76087d0fd6fa834",slug:"plant-defense-mechanisms",bookSignature:"Josphert Ngui Kimatu",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"224171",title:"Prof.",name:"Josphert N.",middleName:null,surname:"Kimatu",slug:"josphert-n.-kimatu",fullName:"Josphert N. Kimatu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10686",title:"Natural Gas",subtitle:"New Perspectives and Future Developments",isOpenForSubmission:!1,hash:"581763788a6a59e653a9d1d9b5a42d79",slug:"natural-gas-new-perspectives-and-future-developments",bookSignature:"Maryam Takht Ravanchi",coverURL:"https://cdn.intechopen.com/books/images_new/10686.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"2416",title:"Dr.",name:"Maryam",middleName:null,surname:"Takht Ravanchi",slug:"maryam-takht-ravanchi",fullName:"Maryam Takht Ravanchi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10988",title:"Railway Transport Planning and Manageme",subtitle:null,isOpenForSubmission:!1,hash:"5cb54cc53caedad9ec78372563c82e2c",slug:"railway-transport-planning-and-management",bookSignature:"Stefano de Luca, Roberta Di Pace and Chiara Fiori",coverURL:"https://cdn.intechopen.com/books/images_new/10988.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"271061",title:"Prof.",name:"Stefano",middleName:null,surname:"de Luca",slug:"stefano-de-luca",fullName:"Stefano de Luca"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"1136",title:"Reproductive Health",slug:"reproductive-health",parent:{id:"200",title:"Public Health",slug:"medicine-public-health"},numberOfBooks:1,numberOfSeries:0,numberOfAuthorsAndEditors:13,numberOfWosCitations:4,numberOfCrossrefCitations:2,numberOfDimensionsCitations:5,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"1136",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"807",title:"Sexual Dysfunctions",subtitle:"Special Issues",isOpenForSubmission:!1,hash:"11e1526b5fdfe634b13cfd6fdd342670",slug:"sexual-dysfunctions-special-issues",bookSignature:"Azita Goshtasebi",coverURL:"https://cdn.intechopen.com/books/images_new/807.jpg",editedByType:"Edited by",editors:[{id:"67991",title:"Dr.",name:"Azita",middleName:null,surname:"Goshtasebi",slug:"azita-goshtasebi",fullName:"Azita Goshtasebi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:1,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"25435",doi:"10.5772/31795",title:"The Effects of Sildenafil Citrate on the Liver and Kidneys of Adult Wistar Rats (Rattus norvegicus) – A Histological Study",slug:"the-effects-of-sildenafil-citrate-on-the-liver-and-kidneys-of-adult-wistar-rats-rattus-norvegicus-a-",totalDownloads:5766,totalCrossrefCites:1,totalDimensionsCites:4,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Andrew Osayame Eweka and Abieyuwa Eweka",authors:[{id:"88694",title:"Dr.",name:"Andrew",middleName:null,surname:"Eweka",slug:"andrew-eweka",fullName:"Andrew Eweka"}]},{id:"25429",doi:"10.5772/26841",title:"Prevalence of Sexual Dysfunctions: A Systemic Approach",slug:"prevalence-of-sexual-dysfunctions-a-systemic-approach",totalDownloads:4215,totalCrossrefCites:1,totalDimensionsCites:1,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Azita Goshtasebi, Samira Behboudi Gandevani, and Abbas Rahimi Foroushani",authors:[{id:"67991",title:"Dr.",name:"Azita",middleName:null,surname:"Goshtasebi",slug:"azita-goshtasebi",fullName:"Azita Goshtasebi"},{id:"71479",title:"Dr.",name:"Abbas",middleName:null,surname:"Rahimi Foroushani",slug:"abbas-rahimi-foroushani",fullName:"Abbas Rahimi Foroushani"},{id:"102945",title:"MSc.",name:"Samira",middleName:null,surname:"Behboudi Gandevani",slug:"samira-behboudi-gandevani",fullName:"Samira Behboudi Gandevani"}]},{id:"25431",doi:"10.5772/26008",title:"Sexual Dysfunction Among Cancer Survivors",slug:"sexual-dysfunction-among-cancer-survivors",totalDownloads:3118,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Atara Ntekim",authors:[{id:"65256",title:"Dr.",name:"Atara",middleName:"I",surname:"Ntekim",slug:"atara-ntekim",fullName:"Atara Ntekim"}]},{id:"25432",doi:"10.5772/26067",title:"Sexual Rehabilitation of People with Physical Disabilities: Sexuality and Spinal Injury",slug:"sexual-rehabilitation-of-people-with-physical-disabilities-sexuality-and-spinal-injury",totalDownloads:1994,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Ana Cláudia Bortolozzi Maia",authors:[{id:"65418",title:"Dr.",name:"Ana Cláudia Bortolozzi",middleName:null,surname:"Maia",slug:"ana-claudia-bortolozzi-maia",fullName:"Ana Cláudia Bortolozzi Maia"}]},{id:"25433",doi:"10.5772/26773",title:"Paradigms for Preclinical Investigations of Female Sexual Function and Dysfunction (HSDD and FSAD)",slug:"paradigms-for-preclinical-investigations-of-female-sexual-function-and-dysfunction-hsdd-and-fsad-",totalDownloads:2097,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Kelly A. Allers and Bernd Sommer",authors:[{id:"67779",title:"Dr.",name:"Kelly",middleName:null,surname:"Allers",slug:"kelly-allers",fullName:"Kelly Allers"}]}],mostDownloadedChaptersLast30Days:[{id:"25432",title:"Sexual Rehabilitation of People with Physical Disabilities: Sexuality and Spinal Injury",slug:"sexual-rehabilitation-of-people-with-physical-disabilities-sexuality-and-spinal-injury",totalDownloads:1994,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Ana Cláudia Bortolozzi Maia",authors:[{id:"65418",title:"Dr.",name:"Ana Cláudia Bortolozzi",middleName:null,surname:"Maia",slug:"ana-claudia-bortolozzi-maia",fullName:"Ana Cláudia Bortolozzi Maia"}]},{id:"25434",title:"Development of Male Sexual Function After Prenatal Modulation of Cholinergic System",slug:"development-of-male-sexual-function-after-prenatal-modulation-of-cholinergic-system",totalDownloads:1309,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Alekber Bairamov, Alina Babenko, Galina Yukina,Elena Grineva, Boris Komikov, Petr Shabanovand and Nikolay Sapronov",authors:[{id:"70584",title:"Dr",name:"Alekber",middleName:null,surname:"Bairamov",slug:"alekber-bairamov",fullName:"Alekber Bairamov"}]},{id:"25431",title:"Sexual Dysfunction Among Cancer Survivors",slug:"sexual-dysfunction-among-cancer-survivors",totalDownloads:3118,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Atara Ntekim",authors:[{id:"65256",title:"Dr.",name:"Atara",middleName:"I",surname:"Ntekim",slug:"atara-ntekim",fullName:"Atara Ntekim"}]},{id:"25429",title:"Prevalence of Sexual Dysfunctions: A Systemic Approach",slug:"prevalence-of-sexual-dysfunctions-a-systemic-approach",totalDownloads:4215,totalCrossrefCites:1,totalDimensionsCites:1,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Azita Goshtasebi, Samira Behboudi Gandevani, and Abbas Rahimi Foroushani",authors:[{id:"67991",title:"Dr.",name:"Azita",middleName:null,surname:"Goshtasebi",slug:"azita-goshtasebi",fullName:"Azita Goshtasebi"},{id:"71479",title:"Dr.",name:"Abbas",middleName:null,surname:"Rahimi Foroushani",slug:"abbas-rahimi-foroushani",fullName:"Abbas Rahimi Foroushani"},{id:"102945",title:"MSc.",name:"Samira",middleName:null,surname:"Behboudi Gandevani",slug:"samira-behboudi-gandevani",fullName:"Samira Behboudi Gandevani"}]},{id:"25435",title:"The Effects of Sildenafil Citrate on the Liver and Kidneys of Adult Wistar Rats (Rattus norvegicus) – A Histological Study",slug:"the-effects-of-sildenafil-citrate-on-the-liver-and-kidneys-of-adult-wistar-rats-rattus-norvegicus-a-",totalDownloads:5766,totalCrossrefCites:1,totalDimensionsCites:4,abstract:null,book:{id:"807",slug:"sexual-dysfunctions-special-issues",title:"Sexual Dysfunctions",fullTitle:"Sexual Dysfunctions - Special Issues"},signatures:"Andrew Osayame Eweka and Abieyuwa Eweka",authors:[{id:"88694",title:"Dr.",name:"Andrew",middleName:null,surname:"Eweka",slug:"andrew-eweka",fullName:"Andrew Eweka"}]}],onlineFirstChaptersFilter:{topicId:"1136",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"June 29th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:32,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"3",title:"Bacterial Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/3.jpg",isOpenForSubmission:!1,editor:null,editorTwo:null,editorThree:null},{id:"4",title:"Fungal Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/4.jpg",isOpenForSubmission:!0,editor:{id:"174134",title:"Dr.",name:"Yuping",middleName:null,surname:"Ran",slug:"yuping-ran",fullName:"Yuping Ran",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9d6QAC/Profile_Picture_1630330675373",biography:"Dr. Yuping Ran, Professor, Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China. Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. Board Member and Chair of Mycology Group of Chinese Society of Dermatology.",institutionString:null,institution:{name:"Sichuan University",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null},{id:"5",title:"Parasitic Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",isOpenForSubmission:!0,editor:{id:"67907",title:"Dr.",name:"Amidou",middleName:null,surname:"Samie",slug:"amidou-samie",fullName:"Amidou Samie",profilePictureURL:"https://mts.intechopen.com/storage/users/67907/images/system/67907.jpg",biography:"Dr. Amidou Samie is an Associate Professor of Microbiology at the University of Venda, in South Africa, where he graduated for his PhD in May 2008. He joined the Department of Microbiology the same year and has been giving lectures on topics covering parasitology, immunology, molecular biology and industrial microbiology. He is currently a rated researcher by the National Research Foundation of South Africa at category C2. He has published widely in the field of infectious diseases and has overseen several MSc’s and PhDs. His research activities mostly cover topics on infectious diseases from epidemiology to control. His particular interest lies in the study of intestinal protozoan parasites and opportunistic infections among HIV patients as well as the potential impact of childhood diarrhoea on growth and child development. He also conducts research on water-borne diseases and water quality and is involved in the evaluation of point-of-use water treatment technologies using silver and copper nanoparticles in collaboration with the University of Virginia, USA. He also studies the use of medicinal plants for the control of infectious diseases as well as antimicrobial drug resistance.",institutionString:null,institution:{name:"University of Venda",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},{id:"6",title:"Viral Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/6.jpg",isOpenForSubmission:!0,editor:{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:10,paginationItems:[{id:"82380",title:"Evolution of Parasitism and Pathogenic Adaptations in Certain Medically Important Fungi",doi:"10.5772/intechopen.105206",signatures:"Gokul Shankar Sabesan, Ranjit Singh AJA, Ranjith Mehenderkar and Basanta Kumar Mohanty",slug:"evolution-of-parasitism-and-pathogenic-adaptations-in-certain-medically-important-fungi",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fungal Infectious Diseases - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11400.jpg",subseries:{id:"4",title:"Fungal Infectious Diseases"}}},{id:"82367",title:"Spatial Variation and Factors Associated with Unsuppressed HIV Viral Load among Women in an HIV Hyperendemic Area of KwaZulu-Natal, South Africa",doi:"10.5772/intechopen.105547",signatures:"Adenike O. Soogun, Ayesha B.M. Kharsany, Temesgen Zewotir and Delia North",slug:"spatial-variation-and-factors-associated-with-unsuppressed-hiv-viral-load-among-women-in-an-hiv-hype",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82193",title:"Enterococcal Infections: Recent Nomenclature and emerging trends",doi:"10.5772/intechopen.104792",signatures:"Kavita Raja",slug:"enterococcal-infections-recent-nomenclature-and-emerging-trends",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"82207",title:"Management Strategies in Perinatal HIV",doi:"10.5772/intechopen.105451",signatures:"Kayla Aleshire and Rima Bazzi",slug:"management-strategies-in-perinatal-hiv",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}}]},overviewPagePublishedBooks:{paginationCount:13,paginationItems:[{type:"book",id:"6667",title:"Influenza",subtitle:"Therapeutics and Challenges",coverURL:"https://cdn.intechopen.com/books/images_new/6667.jpg",slug:"influenza-therapeutics-and-challenges",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"105e347b2d5dbbe6b593aceffa051efa",volumeInSeries:1,fullTitle:"Influenza - Therapeutics and Challenges",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}]},{type:"book",id:"7064",title:"Current Perspectives in Human Papillomavirus",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7064.jpg",slug:"current-perspectives-in-human-papillomavirus",publishedDate:"May 2nd 2019",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"d92a4085627bab25ddc7942fbf44cf05",volumeInSeries:2,fullTitle:"Current Perspectives in Human Papillomavirus",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}]},{type:"book",id:"7123",title:"Current Topics in Neglected Tropical Diseases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7123.jpg",slug:"current-topics-in-neglected-tropical-diseases",publishedDate:"December 4th 2019",editedByType:"Edited by",bookSignature:"Alfonso J. Rodriguez-Morales",hash:"61c627da05b2ace83056d11357bdf361",volumeInSeries:3,fullTitle:"Current Topics in Neglected Tropical Diseases",editors:[{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null}]},{type:"book",id:"7839",title:"Malaria",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7839.jpg",slug:"malaria",publishedDate:"December 11th 2019",editedByType:"Edited by",bookSignature:"Fyson H. Kasenga",hash:"91cde4582ead884cb0f355a19b67cd56",volumeInSeries:4,fullTitle:"Malaria",editors:[{id:"86725",title:"Dr.",name:"Fyson",middleName:"Hanania",surname:"Kasenga",slug:"fyson-kasenga",fullName:"Fyson Kasenga",profilePictureURL:"https://mts.intechopen.com/storage/users/86725/images/system/86725.jpg",biography:"Dr. Kasenga is a graduate of Tumaini University, Kilimanjaro Christian Medical College, Moshi, Tanzania and Umeå University, Sweden. He obtained a Master’s degree in Public Health and PhD in Public Health and Epidemiology. He has a background in Clinical Medicine and has taken courses at higher diploma levels in public health from University of Transkei, Republic of South Africa, and African Medical and Research Foundation (AMREF) in Nairobi, Kenya. Dr. Kasenga worked in different places in and outside Malawi, and has held various positions, such as Licensed Medical Officer, HIV/AIDS Programme Officer, HIV/AIDS resource person in the International Department of Diakonhjemet College, Oslo, Norway. He also managed an Integrated HIV/AIDS Prevention programme for over 5 years. He is currently working as a Director for the Health Ministries Department of Malawi Union of the Seventh Day Adventist Church. Dr. Kasenga has published over 5 articles on HIV/AIDS issues focusing on Prevention of Mother to Child Transmission of HIV (PMTCT), including a book chapter on HIV testing counseling (currently in press). Dr. Kasenga is married to Grace and blessed with three children, a son and two daughters: Happy, Lettice and Sungani.",institutionString:"Malawi Adventist University",institution:{name:"Malawi Adventist University",institutionURL:null,country:{name:"Malawi"}}}]}]},openForSubmissionBooks:{paginationCount:3,paginationItems:[{id:"11601",title:"Econometrics - Recent Advances and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11601.jpg",hash:"bc8ab49e2cf436c217a49ca8c12a22eb",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"May 13th 2022",isOpenForSubmission:!0,editors:[{id:"452331",title:"Dr.",name:"Brian",surname:"Sloboda",slug:"brian-sloboda",fullName:"Brian Sloboda"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12141",title:"Leadership - Advancing Great Leadership Practices and Good Leaders",coverURL:"https://cdn.intechopen.com/books/images_new/12141.jpg",hash:"85f77453916f1d80d80d88ee4fd2f2d1",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 1st 2022",isOpenForSubmission:!0,editors:[{id:"420133",title:"Dr.",name:"Joseph",surname:"Crawford",slug:"joseph-crawford",fullName:"Joseph Crawford"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12139",title:"Global Market and Trade",coverURL:"https://cdn.intechopen.com/books/images_new/12139.jpg",hash:"fa34af07c3a9657fa670404202f8cba5",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"July 21st 2022",isOpenForSubmission:!0,editors:[{id:"243649",title:"Dr.Ing.",name:"Ireneusz",surname:"Miciuła",slug:"ireneusz-miciula",fullName:"Ireneusz Miciuła"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:10,paginationItems:[{id:"82380",title:"Evolution of Parasitism and Pathogenic Adaptations in Certain Medically Important Fungi",doi:"10.5772/intechopen.105206",signatures:"Gokul Shankar Sabesan, Ranjit Singh AJA, Ranjith Mehenderkar and Basanta Kumar Mohanty",slug:"evolution-of-parasitism-and-pathogenic-adaptations-in-certain-medically-important-fungi",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fungal Infectious Diseases - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11400.jpg",subseries:{id:"4",title:"Fungal Infectious Diseases"}}},{id:"82367",title:"Spatial Variation and Factors Associated with Unsuppressed HIV Viral Load among Women in an HIV Hyperendemic Area of KwaZulu-Natal, South Africa",doi:"10.5772/intechopen.105547",signatures:"Adenike O. Soogun, Ayesha B.M. Kharsany, Temesgen Zewotir and Delia North",slug:"spatial-variation-and-factors-associated-with-unsuppressed-hiv-viral-load-among-women-in-an-hiv-hype",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82193",title:"Enterococcal Infections: Recent Nomenclature and emerging trends",doi:"10.5772/intechopen.104792",signatures:"Kavita Raja",slug:"enterococcal-infections-recent-nomenclature-and-emerging-trends",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"82207",title:"Management Strategies in Perinatal HIV",doi:"10.5772/intechopen.105451",signatures:"Kayla Aleshire and Rima Bazzi",slug:"management-strategies-in-perinatal-hiv",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82013",title:"Streamlining Laboratory Tests for HIV Detection",doi:"10.5772/intechopen.105096",signatures:"Ramakrishna Prakash and Mysore Krishnamurthy Yashaswini",slug:"streamlining-laboratory-tests-for-hiv-detection",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"HIV-AIDS - Updates, Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"81972",title:"The Submicroscopic Plasmodium falciparum Malaria in Sub-Saharan Africa; Current Understanding of the Host Immune System and New Perspectives",doi:"10.5772/intechopen.105086",signatures:"Kwame Kumi Asare",slug:"the-submicroscopic-plasmodium-falciparum-malaria-in-sub-saharan-africa-current-understanding-of-the-",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Malaria - Recent Advances, and New Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11576.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"81821",title:"Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination",doi:"10.5772/intechopen.104999",signatures:"Adnan Al-Lahham",slug:"pneumococcal-carriage-in-jordanian-children-and-the-importance-of-vaccination",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"81813",title:"Schistosomiasis: Discovery of New Molecules for Disease Treatment and Vaccine Development",doi:"10.5772/intechopen.104738",signatures:"Andressa Barban do Patrocinio",slug:"schistosomiasis-discovery-of-new-molecules-for-disease-treatment-and-vaccine-development",totalDownloads:14,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"New Horizons for Schistosomiasis Research",coverURL:"https://cdn.intechopen.com/books/images_new/10829.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"81644",title:"Perspective Chapter: Ethics of Using Placebo Controlled Trials for Covid-19 Vaccine Development in Vulnerable Populations",doi:"10.5772/intechopen.104776",signatures:"Lesley Burgess, Jurie Jordaan and Matthew Wilson",slug:"perspective-chapter-ethics-of-using-placebo-controlled-trials-for-covid-19-vaccine-development-in-vu",totalDownloads:22,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"SARS-CoV-2 Variants - Two Years After",coverURL:"https://cdn.intechopen.com/books/images_new/11573.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"80546",title:"Streptococcal Skin and Skin-Structure Infections",doi:"10.5772/intechopen.102894",signatures:"Alwyn Rapose",slug:"streptococcal-skin-and-skin-structure-infections",totalDownloads:64,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}}]},subseriesFiltersForOFChapters:[{caption:"Fungal Infectious Diseases",value:4,count:1,group:"subseries"},{caption:"Parasitic Infectious Diseases",value:5,count:2,group:"subseries"},{caption:"Bacterial Infectious Diseases",value:3,count:3,group:"subseries"},{caption:"Viral Infectious Diseases",value:6,count:4,group:"subseries"}],publishedBooks:{paginationCount:32,paginationItems:[{type:"book",id:"10798",title:"Starch",subtitle:"Evolution and Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/10798.jpg",slug:"starch-evolution-and-recent-advances",publishedDate:"June 28th 2022",editedByType:"Edited by",bookSignature:"Martins Ochubiojo Emeje",hash:"f197f6062c1574a9a90e50a369271bcf",volumeInSeries:33,fullTitle:"Starch - Evolution and Recent Advances",editors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje",profilePictureURL:"https://mts.intechopen.com/storage/users/94311/images/system/94311.jpeg",institutionString:"National Institute for Pharmaceutical Research and Development",institution:{name:"National Institute for Pharmaceutical Research and Development",institutionURL:null,country:{name:"Nigeria"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",slug:"essential-oils-advances-in-extractions-and-biological-applications",publishedDate:"June 23rd 2022",editedByType:"Edited by",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",hash:"742e6cae3a35686f975edc8d7f9afa94",volumeInSeries:32,fullTitle:"Essential Oils - Advances in Extractions and Biological Applications",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira",profilePictureURL:"https://mts.intechopen.com/storage/users/195290/images/system/195290.png",institutionString:"Museu Paraense Emílio Goeldi",institution:{name:"Museu Paraense Emílio Goeldi",institutionURL:null,country:{name:"Brazil"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10839",title:"Protein Detection",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10839.jpg",slug:"protein-detection",publishedDate:"June 23rd 2022",editedByType:"Edited by",bookSignature:"Yusuf Tutar and Lütfi Tutar",hash:"2f1c0e4e0207fc45c936e7d22a5369c4",volumeInSeries:31,fullTitle:"Protein Detection",editors:[{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar",profilePictureURL:"https://mts.intechopen.com/storage/users/158492/images/system/158492.jpeg",institutionString:"University of Health Sciences",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10797",title:"Cell Culture",subtitle:"Advanced Technology and Applications in Medical and Life Sciences",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",slug:"cell-culture-advanced-technology-and-applications-in-medical-and-life-sciences",publishedDate:"June 15th 2022",editedByType:"Edited by",bookSignature:"Xianquan Zhan",hash:"2c628f4757f9639a4450728d839a7842",volumeInSeries:30,fullTitle:"Cell Culture - Advanced Technology and Applications in Medical and Life Sciences",editors:[{id:"223233",title:"Prof.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",profilePictureURL:"https://mts.intechopen.com/storage/users/223233/images/system/223233.png",institutionString:"Shandong First Medical University",institution:{name:"Affiliated Hospital of Shandong Academy of Medical Sciences",institutionURL:null,country:{name:"China"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10841",title:"Hydrolases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10841.jpg",slug:"hydrolases",publishedDate:"June 15th 2022",editedByType:"Edited by",bookSignature:"Sajjad Haider, Adnan Haider and Angel Catalá",hash:"4e868cde273d65a7ff54b1817d640629",volumeInSeries:29,fullTitle:"Hydrolases",editors:[{id:"110708",title:"Dr.",name:"Sajjad",middleName:null,surname:"Haider",slug:"sajjad-haider",fullName:"Sajjad Haider",profilePictureURL:"https://mts.intechopen.com/storage/users/110708/images/system/110708.png",institutionString:"King Saud University",institution:{name:"King Saud University",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10803",title:"Reactive Oxygen Species",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10803.jpg",slug:"reactive-oxygen-species",publishedDate:"April 28th 2022",editedByType:"Edited by",bookSignature:"Rizwan Ahmad",hash:"176adcf090fdd1f93cb8ce3146e79ca1",volumeInSeries:28,fullTitle:"Reactive Oxygen Species",editors:[{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9008",title:"Vitamin K",subtitle:"Recent Topics on the Biology and Chemistry",coverURL:"https://cdn.intechopen.com/books/images_new/9008.jpg",slug:"vitamin-k-recent-topics-on-the-biology-and-chemistry",publishedDate:"March 23rd 2022",editedByType:"Edited by",bookSignature:"Hiroyuki Kagechika and Hitoshi Shirakawa",hash:"8b43add5389ba85743e0a9491e4b9943",volumeInSeries:27,fullTitle:"Vitamin K - Recent Topics on the Biology and Chemistry",editors:[{id:"180528",title:"Dr.",name:"Hiroyuki",middleName:null,surname:"Kagechika",slug:"hiroyuki-kagechika",fullName:"Hiroyuki Kagechika",profilePictureURL:"https://mts.intechopen.com/storage/users/180528/images/system/180528.jpg",institutionString:"Tokyo Medical and Dental University",institution:{name:"Tokyo Medical and Dental University",institutionURL:null,country:{name:"Japan"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10799",title:"Phenolic Compounds",subtitle:"Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10799.jpg",slug:"phenolic-compounds-chemistry-synthesis-diversity-non-conventional-industrial-pharmaceutical-and-therapeutic-applications",publishedDate:"February 23rd 2022",editedByType:"Edited by",bookSignature:"Farid A. Badria",hash:"339199f254d2987ef3167eef74fb8a38",volumeInSeries:26,fullTitle:"Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",institutionString:"Mansoura University",institution:{name:"Mansoura University",institutionURL:null,country:{name:"Egypt"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9659",title:"Fibroblasts",subtitle:"Advances in Inflammation, Autoimmunity and Cancer",coverURL:"https://cdn.intechopen.com/books/images_new/9659.jpg",slug:"fibroblasts-advances-in-inflammation-autoimmunity-and-cancer",publishedDate:"December 22nd 2021",editedByType:"Edited by",bookSignature:"Mojca Frank Bertoncelj and Katja Lakota",hash:"926fa6446f6befbd363fc74971a56de2",volumeInSeries:25,fullTitle:"Fibroblasts - Advances in Inflammation, Autoimmunity and Cancer",editors:[{id:"328755",title:"Ph.D.",name:"Mojca",middleName:null,surname:"Frank Bertoncelj",slug:"mojca-frank-bertoncelj",fullName:"Mojca Frank Bertoncelj",profilePictureURL:"https://mts.intechopen.com/storage/users/328755/images/system/328755.jpg",institutionString:"BioMed X Institute",institution:{name:"University Hospital of Zurich",institutionURL:null,country:{name:"Switzerland"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8977",title:"Protein Kinases",subtitle:"Promising Targets for Anticancer Drug Research",coverURL:"https://cdn.intechopen.com/books/images_new/8977.jpg",slug:"protein-kinases-promising-targets-for-anticancer-drug-research",publishedDate:"December 8th 2021",editedByType:"Edited by",bookSignature:"Rajesh Kumar Singh",hash:"6d200cc031706a565b554fdb1c478901",volumeInSeries:24,fullTitle:"Protein Kinases - Promising Targets for Anticancer Drug Research",editors:[{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8018",title:"Extracellular Matrix",subtitle:"Developments and Therapeutics",coverURL:"https://cdn.intechopen.com/books/images_new/8018.jpg",slug:"extracellular-matrix-developments-and-therapeutics",publishedDate:"October 27th 2021",editedByType:"Edited by",bookSignature:"Rama Sashank Madhurapantula, Joseph Orgel P.R.O. and Zvi Loewy",hash:"c85e82851e80b40282ff9be99ddf2046",volumeInSeries:23,fullTitle:"Extracellular Matrix - Developments and Therapeutics",editors:[{id:"212416",title:"Dr.",name:"Rama Sashank",middleName:null,surname:"Madhurapantula",slug:"rama-sashank-madhurapantula",fullName:"Rama Sashank Madhurapantula",profilePictureURL:"https://mts.intechopen.com/storage/users/212416/images/system/212416.jpg",institutionString:"Illinois Institute of Technology",institution:{name:"Illinois Institute of Technology",institutionURL:null,country:{name:"United States of America"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9759",title:"Vitamin E in Health and Disease",subtitle:"Interactions, Diseases and Health Aspects",coverURL:"https://cdn.intechopen.com/books/images_new/9759.jpg",slug:"vitamin-e-in-health-and-disease-interactions-diseases-and-health-aspects",publishedDate:"October 6th 2021",editedByType:"Edited by",bookSignature:"Pınar Erkekoglu and Júlia Scherer Santos",hash:"6c3ddcc13626110de289b57f2516ac8f",volumeInSeries:22,fullTitle:"Vitamin E in Health and Disease - Interactions, Diseases and Health Aspects",editors:[{id:"109978",title:"Prof.",name:"Pınar",middleName:null,surname:"Erkekoğlu",slug:"pinar-erkekoglu",fullName:"Pınar Erkekoğlu",profilePictureURL:"https://mts.intechopen.com/storage/users/109978/images/system/109978.jpg",institutionString:"Hacettepe University",institution:{name:"Hacettepe University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Proteomics",value:18,count:4},{group:"subseries",caption:"Metabolism",value:17,count:6},{group:"subseries",caption:"Cell and Molecular Biology",value:14,count:9},{group:"subseries",caption:"Chemical Biology",value:15,count:13}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:8},{group:"publicationYear",caption:"2021",value:2021,count:7},{group:"publicationYear",caption:"2020",value:2020,count:12},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:2}],authors:{paginationCount:301,paginationItems:[{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/116250/images/system/116250.jpg",biography:"Professor Nima Rezaei obtained an MD from Tehran University of Medical Sciences, Iran. He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. Govindarajan completed his BSc degree in Zoology at Government Arts College (Autonomous), Kumbakonam, and MSc, MPhil, and PhD degrees at Annamalai University, Annamalai Nagar, Tamil Nadu, India. He is serving as an assistant professor at the Department of Zoology, Annamalai University. His research interests include isolation, identification, and characterization of biologically active molecules from plants and microbes. He has identified more than 20 pure compounds with high mosquitocidal activity and also conducted high-quality research on photochemistry and nanosynthesis. He has published more than 150 studies in journals with impact factor and 2 books in Lambert Academic Publishing, Germany. He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"337446",title:"Dr.",name:"Maria",middleName:null,surname:"Zavala-Colon",slug:"maria-zavala-colon",fullName:"Maria Zavala-Colon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico, Medical Sciences Campus",country:{name:"United States of America"}}},{id:"338856",title:"Mrs.",name:"Nur Alvira",middleName:null,surname:"Pascawati",slug:"nur-alvira-pascawati",fullName:"Nur Alvira Pascawati",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universitas Respati Yogyakarta",country:{name:"Indonesia"}}},{id:"441116",title:"Dr.",name:"Jovanka M.",middleName:null,surname:"Voyich",slug:"jovanka-m.-voyich",fullName:"Jovanka M. Voyich",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Montana State University",country:{name:"United States of America"}}},{id:"330412",title:"Dr.",name:"Muhammad",middleName:null,surname:"Farhab",slug:"muhammad-farhab",fullName:"Muhammad Farhab",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"349495",title:"Dr.",name:"Muhammad",middleName:null,surname:"Ijaz",slug:"muhammad-ijaz",fullName:"Muhammad Ijaz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}}]}},subseries:{item:{id:"10",type:"subseries",title:"Animal Physiology",keywords:"Physiology, Comparative, Evolution, Biomolecules, Organ, Homeostasis, Anatomy, Pathology, Medical, Cell Division, Cell Signaling, Cell Growth, Cell Metabolism, Endocrine, Neuroscience, Cardiovascular, Development, Aging, Development",scope:"Physiology, the scientific study of functions and mechanisms of living systems, is an essential area of research in its own right, but also in relation to medicine and health sciences. The scope of this topic will range from molecular, biochemical, cellular, and physiological processes in all animal species. Work pertaining to the whole organism, organ systems, individual organs and tissues, cells, and biomolecules will be included. Medical, animal, cell, and comparative physiology and allied fields such as anatomy, histology, and pathology with physiology links will be covered in this topic. Physiology research may be linked to development, aging, environment, regular and pathological processes, adaptation and evolution, exercise, or several other factors affecting, or involved with, animal physiology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/10.jpg",hasOnlineFirst:!1,hasPublishedBooks:!1,annualVolume:11406,editor:{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",biography:"Catrin Rutland is an Associate Professor of Anatomy and Developmental Genetics at the University of Nottingham, UK. She obtained a BSc from the University of Derby, England, a master’s degree from Technische Universität München, Germany, and a Ph.D. from the University of Nottingham. She undertook a post-doctoral research fellowship in the School of Medicine before accepting tenure in Veterinary Medicine and Science. Dr. Rutland also obtained an MMedSci (Medical Education) and a Postgraduate Certificate in Higher Education (PGCHE). She is the author of more than sixty peer-reviewed journal articles, twelve books/book chapters, and more than 100 research abstracts in cardiovascular biology and oncology. She is a board member of the European Association of Veterinary Anatomists, Fellow of the Anatomical Society, and Senior Fellow of the Higher Education Academy. Dr. Rutland has also written popular science books for the public. https://orcid.org/0000-0002-2009-4898. www.nottingham.ac.uk/vet/people/catrin.rutland",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}},editorTwo:null,editorThree:null,series:{id:"10",title:"Physiology",doi:"10.5772/intechopen.72796",issn:"2631-8261"},editorialBoard:[{id:"306970",title:"Mr.",name:"Amin",middleName:null,surname:"Tamadon",slug:"amin-tamadon",fullName:"Amin Tamadon",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002oHR5wQAG/Profile_Picture_1623910304139",institutionString:null,institution:{name:"Bushehr University of Medical Sciences",institutionURL:null,country:{name:"Iran"}}},{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón",slug:"juan-carlos-gardon",fullName:"Juan Carlos Gardón",profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",institutionString:"Catholic University of Valencia San Vicente Mártir, Spain",institution:null},{id:"245306",title:"Dr.",name:"María Luz",middleName:null,surname:"Garcia Pardo",slug:"maria-luz-garcia-pardo",fullName:"María Luz Garcia Pardo",profilePictureURL:"https://mts.intechopen.com/storage/users/245306/images/system/245306.png",institutionString:null,institution:{name:"Miguel Hernandez University",institutionURL:null,country:{name:"Spain"}}},{id:"283315",title:"Prof.",name:"Samir",middleName:null,surname:"El-Gendy",slug:"samir-el-gendy",fullName:"Samir El-Gendy",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRduYQAS/Profile_Picture_1606215849748",institutionString:null,institution:{name:"Alexandria University",institutionURL:null,country:{name:"Egypt"}}},{id:"178366",title:"Dr.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",institutionString:"Kafkas University",institution:{name:"Kafkas University",institutionURL:null,country:{name:"Turkey"}}}]},onlineFirstChapters:{paginationCount:6,paginationItems:[{id:"82135",title:"Carotenoids in Cassava (Manihot esculenta Crantz)",doi:"10.5772/intechopen.105210",signatures:"Lovina I. Udoh, Josephine U. Agogbua, Eberechi R. Keyagha and Itorobong I. Nkanga",slug:"carotenoids-in-cassava-manihot-esculenta-crantz",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"81576",title:"Carotenoids in Thermal Adaptation of Plants and Animals",doi:"10.5772/intechopen.104537",signatures:"Ivan M. Petyaev",slug:"carotenoids-in-thermal-adaptation-of-plants-and-animals",totalDownloads:25,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Ivan",surname:"Petyaev"}],book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"81358",title:"New Insights on Carotenoid Production by Gordonia alkanivorans Strain 1B",doi:"10.5772/intechopen.103919",signatures:"Tiago P. Silva, Susana M. Paixão, Ana S. Fernandes, José C. Roseiro and Luís Alves",slug:"new-insights-on-carotenoid-production-by-gordonia-alkanivorans-strain-1b",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"81246",title:"Role of Carotenoids in Cardiovascular Disease",doi:"10.5772/intechopen.102750",signatures:"Arslan Ahmad, Sakhawat Riaz, Muhammad Shahzaib Nadeem, Umber Mubeen and Khadija Maham",slug:"role-of-carotenoids-in-cardiovascular-disease",totalDownloads:34,totalCrossrefCites:1,totalDimensionsCites:1,authors:null,book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"81159",title:"Potential of Carotenoids from Fresh Tomatoes and Their Availability in Processed Tomato-Based Products",doi:"10.5772/intechopen.103933",signatures:"Rose Daphnee Ngameni Tchonkouang, Maria Dulce Carlos Antunes and Maria Margarida Cortês Vieira",slug:"potential-of-carotenoids-from-fresh-tomatoes-and-their-availability-in-processed-tomato-based-produc",totalDownloads:30,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"80902",title:"Computational Chemistry Study of Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates as Therapeutic Drugs",doi:"10.5772/intechopen.103130",signatures:"Norma Flores-Holguín, Juan Frau and Daniel Glossman-Mitnik",slug:"computational-chemistry-study-of-natural-apocarotenoids-and-their-synthetic-glycopeptide-conjugates-",totalDownloads:33,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Norma",surname:"Flores-Holguín"},{name:"Daniel",surname:"Glossman-Mitnik"},{name:"Juan",surname:"Frau"}],book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}}]},publishedBooks:{paginationCount:4,paginationItems:[{type:"book",id:"10839",title:"Protein Detection",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10839.jpg",slug:"protein-detection",publishedDate:"June 23rd 2022",editedByType:"Edited by",bookSignature:"Yusuf Tutar and Lütfi Tutar",hash:"2f1c0e4e0207fc45c936e7d22a5369c4",volumeInSeries:31,fullTitle:"Protein Detection",editors:[{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar",profilePictureURL:"https://mts.intechopen.com/storage/users/158492/images/system/158492.jpeg",institutionString:"University of Health Sciences",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8977",title:"Protein Kinases",subtitle:"Promising Targets for Anticancer Drug Research",coverURL:"https://cdn.intechopen.com/books/images_new/8977.jpg",slug:"protein-kinases-promising-targets-for-anticancer-drug-research",publishedDate:"December 8th 2021",editedByType:"Edited by",bookSignature:"Rajesh Kumar Singh",hash:"6d200cc031706a565b554fdb1c478901",volumeInSeries:24,fullTitle:"Protein Kinases - Promising Targets for Anticancer Drug Research",editors:[{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9742",title:"Ubiquitin",subtitle:"Proteasome Pathway",coverURL:"https://cdn.intechopen.com/books/images_new/9742.jpg",slug:"ubiquitin-proteasome-pathway",publishedDate:"December 9th 2020",editedByType:"Edited by",bookSignature:"Xianquan Zhan",hash:"af6880d3a5571da1377ac8f6373b9e82",volumeInSeries:18,fullTitle:"Ubiquitin - Proteasome Pathway",editors:[{id:"223233",title:"Prof.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",profilePictureURL:"https://mts.intechopen.com/storage/users/223233/images/system/223233.png",institutionString:"Shandong First Medical University",institution:{name:"Affiliated Hospital of Shandong Academy of Medical Sciences",institutionURL:null,country:{name:"China"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"6820",title:"Keratin",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6820.jpg",slug:"keratin",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Miroslav Blumenberg",hash:"6def75cd4b6b5324a02b6dc0359896d0",volumeInSeries:2,fullTitle:"Keratin",editors:[{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.png",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}},{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}}]},submityourwork:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],subseriesList:[{id:"14",title:"Cell and Molecular Biology",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression"},{id:"15",title:"Chemical Biology",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors"},{id:"17",title:"Metabolism",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation"},{id:"18",title:"Proteomics",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:null},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/65891",hash:"",query:{},params:{id:"65891"},fullPath:"/chapters/65891",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()