Discretization of the values to determine the supply of energy in the Araucanía region, according to the different demand criteria.
\r\n\tThis book will provide information about fouling mitigation in general and the ecofriendly methods of fouling mitigation. Chapters from this book will inform the readers about fouling models and predictive maintenance of the equipment prone to fouling. Adaptive means for prolonged continuous operation will also be addressed. This book will guide the readers in selection of fouling mitigation approaches for different applications. A brief discussion on economic impact of fouling in different industries will also be part of this book.
",isbn:null,printIsbn:"979-953-307-X-X",pdfIsbn:null,doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,hash:"f31d1d99cc6caac249973b404ae9091a",bookSignature:"Dr. Salim Newaz Kazi",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/9022.jpg",keywords:"Scales and Deposits, Water Chemistry, Types of Fouling, Mechanism of Fouling, Fouling in Chemical Industries, Fouling in Dairy Industries, Membrane and Filtration, Membrane Fouling, Characterize Scales, Dissolution of Deposits, Conventional Fouling Mitigation, Ecofriendly Ways of Mitigation",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"May 16th 2019",dateEndSecondStepPublish:"February 14th 2020",dateEndThirdStepPublish:"April 14th 2020",dateEndFourthStepPublish:"July 3rd 2020",dateEndFifthStepPublish:"September 1st 2020",remainingDaysToSecondStep:"2 years",secondStepPassed:!0,currentStepOfPublishingProcess:5,editedByType:null,kuFlag:!1,biosketch:null,coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"93483",title:"Prof.",name:"Md Salim Newaz",middleName:null,surname:"Kazi",slug:"md-salim-newaz-kazi",fullName:"Md Salim Newaz Kazi",profilePictureURL:"https://mts.intechopen.com/storage/users/93483/images/system/93483.jpg",biography:"Dr. S. N. Kazi is a Professor of Mechanical Engineering at the University of Malaya. He has a specialization in Heat Transfer, Fluid Mechanics, Particle Characterization, Heat Exchanger Fouling Mitigation, Nanofluid synthesis and applications, and Renewable Energy. He has a long Engineering service experience in Petrochemical Industries. He also worked as a consultant for different Engineering Companies. Dr. Kazi has an academic background with the B. Sc., M. Sc., and M. S. in Mechanical Engineering. He received his Ph.D. in Chemical and Materials Engineering. He is a member of many professional bodies and an editorial member of many journals. He has been working as an academic since 2009. 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From chapter submission and review, to approval and revision, copy-editing and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. 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In South America, it is estimated that a 1% increase in energy consumption translates to a 0.42% increase in economic growth [1]. In countries, such as Chile, where 59.3% of the primary energy matrix is imported, with 90.2% of this from fossil fuels [2], uncertainty and insecurity arise in the energy supplies and dependence on foreign markets, obliging the assumption of risk in the face of possible fluctuations [1].
\nAlternative sources of energy that are renewable and have a reduced environmental impact are required to reduce the use of nonrenewable energy sources, such as fossil fuels [3], which have negative effects, such as climate change, forest destruction, and the extinction of species [3, 4].
\nRenewable energy offers environmental benefits and increases the standard of living for various populations, diversifies the energy matrix, improves the infrastructure, promotes technology transfer, and provides other positive effects [4, 5]. Biofuels are nonconventional renewable energy sources (NCRECs) that may replace fossil fuels, lowering the dependence on international markets and the atmospheric emissions of greenhouse gases (EGGs) [6].
\nChile promised, in 2010, to reduce emissions by 20% below the 2020 projection [7]; however, according to current trends, an increase of 360% is projected in carbon dioxide (CO2) emissions in electricity generation and transportation. The aforementioned items currently represent 0.3% of the total emissions globally [8].
\nFirewood and biofuels are the second source of energy for Chile. They are entirely produced within the country, representing 28.9% of the primary energy matrix in 2013 [9]. Here, 36% of the national population is concentrated between the O’Higgins and Aysén Regions, with 74% of these homes consuming firewood or its derivatives [10] for heating or cooking systems. Biofuel is used for self-produced electricity [11].
\nThe residual biomass from agricultural activities has an average caloric power of 17,500 kJ kg−1 [12] and is underused in Chile [2, 13]. Cereal production residue is concentrated in the central south area of the country, particularly in the regions of Araucanía (29.3%) and Libertador Bernardo O’Higgins (19.8%) as the main cereal residue producers [14].
\nWheat is the main cereal produced in Chile, representing 32.9% of the planted agricultural surface during the 2016/2017 agricultural season [15]. The Araucanía Region is the main wheat production region in the country. During the 2016/2017 agricultural season, 42.0% of the total surface area of planted wheat was concentrated here, yielding a production of approximately 597,835 tons [16].
\nRomán-Figueroa et al. [2] determined that, in the Araucanía Region, 50% of the production of wheat residuals was concentrated in 23 (of 299) census districts, while 10 of these districts produced 27.8% of the residues. The majority was produced in the central valley of the region, specifically in the province of Malleco, which has a regional coverage of 60,800 ha [2]. Currently, the agricultural residue is burnt [17, 18], which causes environmental problems owing to the emission of EGGs, as well as public health problems owing to particulate matter emissions [17, 19].
\nElectricity production from agricultural residue biomass has been widely studied and recommended, owing to the low production costs, high conversion efficiency, and environmental benefits because it is carbon neutral [20, 21]. Singh [21] determined, in the Punjab, India region, production of between 2375 and 2937 MWel was possible depending on the efficiency of the conversion plant, with more than 22,000 million tons of residue. In the Araucanía Region, a 5.0 MWth plant and 27,000 tons of residue, between 3.17 MWel and 4.89 MWel, can be produced using fluidized bed combustion technology with a generation turbine (C/ST) and gasification of the fluidized bed followed by a combined cycle of gas and vapor (G/CC), respectively [2].
\nVarious studies have determined the optimal location of a biomass-based energy production plant using geographic information systems (GIS) [21, 22, 23, 24, 25]. With GIS, evaluation using different attributes and maps to determine the optimal energy production plant location is feasible, [23, 25]. A multi-criteria analysis (MCA) evaluates, using different criteria or factors, a group of opposed real alternatives, considering different development visions and objectives [25]. Therefore, an evaluation considering economic, social, and environmental criteria is possible, optimizing the decision-making process [23].
\nIn Chile, Villamar et al. [23] evaluated the possibility of installing an anaerobic co-digestion plant using discarded agribusiness materials (animal dung and agricultural residues) in the Biobío Region. Using a hierarchical analysis process, they considered factors that were social (distances to residential areas and roads) and economic (residue production, distance to residue production sites, proximity between residue production sites, and closeness of the production plant to roads) [23]. This is the only evaluation of the installation of a residual biomass-based bioenergy plant in the country.
\nThe objective of this study was to determine the optimal location for an energy production plant, which was based on wheat residue in the Araucanía Region of Chile. Three different types of demands were considered: current, potential, and social demands. Three scenarios were used to determine the location of the energy production plant based on wheat residue biomass.
\nThe area of study was the Araucanía Region, located between 37°35′ and 39°37′ southern latitude and from 70°50′ western longitude to the Pacific Ocean, an area of 31,842 km2 (Figure 1). The study was realized at a district level according to the census boundaries determined by the National Institute of Statistics [26].
\nStudy area of Araucanía region, Chile, on a district scale.
The areas were determined with priority assigned to the energy supply, according to three types of demand: current (or high demand), potential, and social. The current demand refers to the sectors with a high consumption. The potential demand refers to the non-covered demand, such as the districts without electricity. The social demand refers to areas where heating or electrical energy should be locally supplied to homes, schools, or treatment centers.
\nDifferent criteria were employed to determine the demand in each case. The current demand considers consumers in the industrial [27] and residential sectors [28]. For the potential demand, the demand for electrical services that are not yet provided is considered [29]; and in the social demand, the demand for energy (thermal and electrical) for services (education and healthcare) and rural homes is considered.
\nEach criterion was standardized with values between 1 and 7, with 1 representing the worst condition and 7 representing the best condition for each criterion.
\nFor the current demand, the distance to the industries, industries quantity per district [30], and the residential energy consumption were considered [30, 31]. All criteria were discretized with values between 1 and 7 (Table 1). For the potential demand, those districts with an electrical coverage of less than 40% were considered, according to the 2006 CASEN [28]. These were discretized with values between 1 and 7. However, only odd values were used owing to the quantity of ranges available (Table 1). For the social demand, the distance to rural settlements, which corresponded to the villages, as well as the distances to primary healthcare centers and rural educational establishments were considered [32]. These were discretized with values between 1 and 7, with 7 representing the shortest distance (Table 1).
\nValue | \nCurrent | \nPotential | \nSocial | \n||||
---|---|---|---|---|---|---|---|
Industries (m) | \nIndustries (number) | \nEnergy consumption (MW) | \nCoverage (%) | \nVillages (m) | \nPrimary healthcare (m) | \nRural educational (m) | \n|
7 | \n0–21,300 | \n7–8 | \n2000–12,000 | \n0–10 | \n0–9531 | \n0–4572 | \n0–4019 | \n
6 | \n21,300–42,600 | \n6 | \n1600–2000 | \n— | \n9531–19,062 | \n4572–9145 | \n4019–8038 | \n
5 | \n42,600–63,900 | \n5 | \n1300–1600 | \n10–20 | \n19,062–28,593 | \n9145–13,717 | \n8038–12,057 | \n
4 | \n63,900–85,201 | \n4 | \n1000–1300 | \n— | \n28,593–38,124 | \n13,717–18,289 | \n12,057–16,076 | \n
3 | \n85,201–106,501 | \n3 | \n700–1000 | \n20–30 | \n38,124–47,655 | \n18,289–22,861 | \n16,076–20,095 | \n
2 | \n106,501–127,801 | \n2 | \n400–700 | \n— | \n47,655–57,186 | \n22,861–27,434 | \n20,095–24,114 | \n
1 | \n127,801–149,101 | \n1 | \n0–400 | \n30–40 | \n57,186–66,717 | \n27,434–32,006 | \n24,114–28,133 | \n
Discretization of the values to determine the supply of energy in the Araucanía region, according to the different demand criteria.
Based on the type of demand and the multi-criteria evaluation (MCE), weights or considerations were assigned to each criterion (Table 2). The priority sites were determined, considering each type of demand (current, potential, and social). Finally, the set of demands was evaluated, where each demand was given a consideration value of 0.33. Thereafter, the energy demand information was used to determine the location of an energy production plant based on biomass in the Araucanía Region.
\nCurrent demand | \nPotential demand | \nSocial demand | \n|||
---|---|---|---|---|---|
Criterion | \nWeighting | \nCriterion | \nWeighting | \nCriterion | \nWeighting | \n
Distance to the industries | \n0.25 | \nElectrical coverage | \n1.0 | \nPrimary healthcare | \n0.33 | \n
Industry quantity | \n0.25 | \n\n | \n | Rural educational | \n0.33 | \n
Energy consumption | \n0.5 | \n\n | \n | Villages | \n0.33 | \n
Consideration of the criteria analyses in the MCE to determine the locations with the highest energy demand (high, potential, and social).
Determining the location of an energy production plant based on biomass was carried out according to a decision rule, where the MCE was used with an analytic hierarchy process (AHP). The use of these combined techniques is a common methodology employed to determine the installation location of energy production plants [29, 33].
\nCriteria selection is required for making decisions. Possible alternatives must be quantified and must contribute to the decision-making process [33, 34, 35]. These criteria may be factors or limiters. A factor is a criterion that negatively or positively affects the possible location for the energy production plant, while a limiter (or exclusion criterion) restricts the location potential, excluding possible installation [33, 34].
\nThe factors employed in this evaluation were as follows:
Availability of biomass: The districts with a greater production of wheat residue biomass according to the estimates by Román-Figueroa et al. [2] were considered the most appropriate; however, this was not established as an exclusion criterion.
Energy consumption priority areas: These were established according to the energy demand scenarios previously calculated: high demand, social demand, and potential demand. The selected sectors with a high demand were considered a priority and more suitable.
Land use/coverage: The installation of an energy production plant must comply with the legal requirements and land usage. Competition with other current uses of the land must be avoided, allowing current activities to continue. The areas considered feasible for the installation of a plant were those without vegetation, meadows, or scrub and were industrial use lands. Urban areas and lands of agricultural use were considered unsuitable because other activities are carried out there that are relevant to society [33, 34].
Roads: Connectivity is essential for the supply of raw materials to the plant; thus, the transport of raw materials should be considered [33, 36]. Therefore, a maximum distance of 1.0 km between the energy plant and the road was considered a priority. Moreover, the type of road material affects accessibility, and thus, this was considered a factor.
Electrical network: Wheat residue was considered the raw material for electricity production [2]. The distance from the energy production plant to the electrical network is relevant to the electricity generated in the electrical supply network. Nonconventional renewable energy (NCRE), such as a generation less than 9.0 MWel, can directly connect to the Chilean distribution network [37]. This would provide an economic benefit to plant installation. A maximum distance of 3.0 km between the energy plant and the electrical network was considered a priority.
Each of these factors was discretized with values between 1 and 7, with 7 as the most suitable (Table 3).
\nValue | \nResidual biomass (t year−1) | \nLand use/coverage | \nRoad types | \nElectrical network (m) | \n
---|---|---|---|---|
7 | \n23,217–27,086 | \nGrassland and scrubland | \nAsphalt | \n0–1000 | \n
6 | \n19,347–23,217 | \n— | \n— | \n1000–2000 | \n
5 | \n15,478–19,347 | \nIndustrial and urban area | \nGravel | \n2000–3000 | \n
4 | \n11,608–15,478 | \n— | \n— | \n3000–12,000 | \n
3 | \n7739–11,608 | \nPrimary and secondary forest | \nDirt | \n12,000–21,000 | \n
2 | \n3869–7730 | \n— | \n— | \n— | \n
1 | \n0–3869 | \nAgricultural land and plantations | \n— | \n— | \n
Discretization of the values for the factors used to determine the optimal location of an energy production plant based on the wheat biomass in the Araucanía region.
Conversely, the following limiters were considered:
Restricted areas: This represents zones where installation is not viable for environmental, legal, or other reasons [33, 34]. These areas include those covered by the protected forest areas system (SNASPE), protected private areas (PPAs), bodies of water, cities, and the current road network. A value of 0 was assigned to the limiter areas, and 1 was assigned to those without restrictions.
Availability of biomass: Districts where the minimum quantity of wheat residue is required for the production of 1 MWel were considered as feasible, such as the districts with a residue production less than 8534.8 t year−1, for a plant with fluidized bed combustion and a generating turbine (C/ST), and 5536.1 t year−1, for a plant with fluidized bed gasifiers followed by a combined cycle of gas and steam (G/CC), based on the study carried out by Román-Figueroa et al. [2]. A value of 0 was assigned to the districts with residue production less than the minimum required to produce 1 MWel, while other districts with higher production were assigned a value of 1. Depending on the situation, the availability of biomass was used as a factor, with the production of biomass being classified with values from 1 to 7 (Table 3). C/ST and G/CC were considered independently as technologies for energy production.
An AHP was used to determine the best location for an energy production plant using wheat biomass as a raw material. The main criterion for the plant location was the biomass supply, by which other major criteria were determined. The analysis was carried out considering the energy demand scenarios (current, potential, and social) as part of the analysis.
\nIn the AHP, an importance value was assigned to each criterion according to its objective. The value scale ranged from 1 to 9, where 1 was considered to be equally important for two criteria (a and b) and 9 was considered to be more important for one criterion than another (a over b) [38, 39]. Therefore, when the relative importance of a over b was established, a value of 1/9 was automatically established [39].
Social scenario: The objective was to satisfy rural sector energy needs, supplying services to healthcare, educational, and rural resident sectors. This scenario was based on social and potential demand, and therefore, industrial and residential (that already have supply) sectors were not considered in this scenario. The availability of biomass, use of land, roads, and electrical supply network were considered as factors. Each of these factors was considered with a different relative weight (Table 4).
Feasibility scenario: The objective was to install an energy production plant based on the biomass, and thus, the residual biomass was considered as a limiter, 8534.8 t year−1 for C/ST and 5536.1 t year−1 for G/CC [2]. The areas with an energy demand had less relevance than other criteria because the availability of the raw material is most relevant (Table 4).
Demand scenario: The objective was to satisfy large consumer demand; therefore, the high-demand scenario was used, where priority was assigned to industrial and residential sectors that currently receive electricity. This was not considered relevant for rural sectors that do not receive. The electrical network had a greater relevance in this scenario because of the goal to satisfy the current energy demand (Table 4).
Criterion | \nSocial scenario | \n|||||
---|---|---|---|---|---|---|
Biomass | \nSocial demand | \nPotential demand | \nLand use | \nRoads | \nElectrical network | \n|
Biomass | \n1 | \n3 | \n3 | \n5 | \n5 | \n5 | \n
Social demand | \n1/3 | \n1 | \n1 | \n3 | \n3 | \n3 | \n
Potential demand | \n1/3 | \n1 | \n1 | \n3 | \n3 | \n3 | \n
Land use | \n1/5 | \n1/3 | \n1/3 | \n1 | \n1 | \n1 | \n
Road | \n1/5 | \n1/3 | \n1/3 | \n1 | \n1 | \n1 | \n
Electrical network | \n1/5 | \n1/3 | \n1/3 | \n1 | \n1 | \n1 | \n
\n | Feasibility scenario | \n|||||
\n | Priority areas | \nLand use | \nRoads | \nElectrical network | \n\n | \n |
Priority areas | \n1 | \n1/7 | \n1/7 | \n1/7 | \n\n | \n |
Land use | \n7 | \n1 | \n1 | \n1 | \n\n | \n |
Road | \n7 | \n1 | \n1 | \n1 | \n\n | \n |
Electrical network | \n7 | \n1 | \n1 | \n1 | \n\n | \n |
\n | Demand scenario | \n|||||
\n | Biomass | \nCurrent demand | \nLand use | \nRoads | \nElectrical network | \n\n |
Biomass | \n1 | \n3 | \n7 | \n7 | \n7 | \n\n |
Current demand | \n1/3 | \n1 | \n7 | \n7 | \n7 | \n\n |
Land use | \n1/7 | \n1/7 | \n1 | \n1 | \n1 | \n\n |
Road | \n1/7 | \n1/7 | \n1 | \n1 | \n1 | \n\n |
Electrical network | \n1/7 | \n1/7 | \n1 | \n1 | \n1 | \n\n |
Valorization of the different criteria used to determine the optimal location of a production plant based on the biomass according to the social, feasibility, and demand scenarios.
\n
High demand: This scenario was created based on the number of industries, distance to the industry, and current energy consumption existing in the region. The industries in the Araucanía Region are concentrated in the municipalities of Angol and Temuco. This is because the municipalities are the capitals of the provinces of Malleco and Cautín, respectively. They are also the cities with a large labor and economic importance, along with Villarica, in the Araucanía Region [40]. Conversely, the current energy consumption in the region generally occurs in the municipalities of Temuco, Ercilla, Cunco, Perquenco, and Freire and to a lesser degree in Angol, Villarrica, and Pucón. These municipalities concentrate the populations; besides, they are located in Ruta 5 road or they are the main touristic centers in the Araucanía Region [40]. Because of the greater consideration placed on the residential electrical consumption (0.5) than that of the quantities of and distances to the industries (0.25 for each one; Table 2), the high-demand scenario concentrated on the same municipalities (Figure 2a).
Potential demand: This scenario was created based on the existing rural electricity required in the Araucanía Region, which is one of the regions with the least amount of rural electricity in Chile [41]. Therefore, the districts with electrical coverage less than 40% were given priority. These districts are principally located in the mountain or costal area of the region and the extreme north and south. The total surface area of the districts with these characteristics was 447,954 ha (Figure 2b).
Social demand: This scenario was based on rural establishments (educational and healthcare facilities and villages), prioritizing the energy supply to these locations. All priority sites under this scenario were located following the central axis with the most populated municipalities, Angol, Victoria, and Temuco [40], distributing to west and southwest of Temuco, covering rural coast municipalities, Carahue, Teodoro Schmidt, Saavedra, and Nueva Toltén (Figure 2c).
Sites with a higher energy demand according to the (a) high demand, (b) potential demand, (c) social demand scenarios, and (d) priority energy demand sites according to the three demand scenarios in the Araucanía region.
Information for each of the scenarios was cross-matched linearly to determine the priority energy demand sites. The priority sites occupied an irregular distribution in the territory (Figure 2d) and covered approximately 548,134 ha (17.2% of the regional surface).
\nThe availability of the wheat biomass residue, considered a biomass production of 8534.8 t year−1 for C/ST and 5536.1 t year−1 for G/CC in the Araucanía Region, was concentrated in the central valley, in the south of the Malleco Province and in the north of the Cautín Province (Figure 3a) [2]. The usable land for installing an energy production plant is mainly located in the peripheral areas of the region, to the south and in the Andes Cordillera. The central area has a greater level of agricultural and industrial development (Figure 3b); however, the distribution of the development could be modified by reducing the use of scrubland meadows; the locations with a higher priority for an energy plant may be hindered by agricultural use [42].
\nPrioritization of the criteria established for the installation of an energy production plant based on the wheat residue biomass in the Araucanía region: (a) biomass production on a district-wide basis, (b) land use, (c) road network, and (d) distance to the electricity distribution network.
The road network is a central paved axis, which corresponds to Route 5 that runs from the north to the south of the region. There are a series of secondary paved roads that run perpendicular to this route. Generally, paved roads are scarce, while gravel roads represent the densest network of roads in the region and are distributed toward the coastal area. Finally, dirt roads are found in the peripheral areas and are scarce (Figure 3c). The distance to the electrical distribution network displayed a similar pattern to that of the road network. A concentration of smaller distances to the network in the central and west areas was observed, while places with larger distance were found in the northeast region. Distances greater than 21,000 m were recorded (Figure 3d).
\nStandardized matrixes and priority vectors were established (or standardized vectors) for each of the priority placement scenarios (social, feasibility, and demand) for each energy production plant based on the wheat biomass (Table 5).
\nCriterion | \nSocial scenario | \n||||||
---|---|---|---|---|---|---|---|
Biomass | \nSocial demand | \nPotential demand | \nLand use | \nRoads | \nElectrical network | \nPVE | \n|
Biomass | \n0.4412 | \n0.5000 | \n0.5000 | \n0.3571 | \n0.3571 | \n0.3571 | \n0.4188 | \n
Social demand | \n0.1471 | \n0.1667 | \n0.1667 | \n0.2143 | \n0.2143 | \n0.2143 | \n0.1872 | \n
Potential demand | \n0.1471 | \n0.1667 | \n0.1667 | \n0.2143 | \n0.2143 | \n0.2143 | \n0.1872 | \n
Land use | \n0.0882 | \n0.0556 | \n0.0556 | \n0.0714 | \n0.0714 | \n0.0714 | \n0.0689 | \n
Road | \n0.0882 | \n0.0556 | \n0.0556 | \n0.0714 | \n0.0714 | \n0.0714 | \n0.0689 | \n
Electrical network | \n0.0882 | \n0.0556 | \n0.0556 | \n0.0714 | \n0.0714 | \n0.0714 | \n0.0689 | \n
\n | Feasibility scenario | \n||||||
\n | Priority areas | \nLand use | \nRoads | \nElectrical network | \n\n | \n | PVE | \n
Priority areas | \n0.0455 | \n0.0455 | \n0.0455 | \n0.0455 | \n\n | \n | 0.0455 | \n
Land use | \n0.3182 | \n0.3182 | \n0.3182 | \n0.3182 | \n\n | \n | 0.3182 | \n
Road | \n0.3182 | \n0.3182 | \n0.3182 | \n0.3182 | \n\n | \n | 0.3182 | \n
Electrical network | \n0.3182 | \n0.3182 | \n0.3182 | \n0.3182 | \n\n | \n | 0.3182 | \n
\n | Demand scenario | \n||||||
\n | Biomass | \nCurrent demand | \nLand use | \nRoads | \nElectrical network | \n\n | PVE | \n
Biomass | \n0.5676 | \n0.6774 | \n0.4118 | \n0.4118 | \n0.4118 | \n\n | 0.4961 | \n
Current demand | \n0.1892 | \n0.2258 | \n0.4118 | \n0.4118 | \n0.4118 | \n\n | 0.3301 | \n
Land use | \n0.0811 | \n0.0323 | \n0.0588 | \n0.0588 | \n0.0588 | \n\n | 0.0580 | \n
Road | \n0.0811 | \n0.0323 | \n0.0588 | \n0.0588 | \n0.0588 | \n\n | 0.0580 | \n
Electrical network | \n0.0811 | \n0.0323 | \n0.0588 | \n0.0588 | \n0.0588 | \n\n | 0.0580 | \n
Standardized matrices and priority vectors used to determine the optimal location of an energy production plant in the Araucanía region, according to the social, feasibility, and demand scenarios.
An evaluation of the consistency in the priority evaluation matrices is relevant in AHP to avoid inconsistencies in the final matrix [33, 38, 43, 44]. Thus, a consistency reason (CR) was used. A consistency index (CI) and a randomness index (RI) were used to calculate the CR [33, 38, 44]. The CRs in the social and demand scenario matrices were 0.019 (CI: 0.023 and RI: 1.24) and 0.049 (CI: 0.056 and RI: 1.12), respectively. This showed that the matrices were consistent, since the inconsistencies of the chosen weights were less than 10% [38, 44]. For the feasibility scenario matrix, the column values were the same for all criteria, showing that the weights (values) used were consistent; therefore, a consistency analysis does not need to be performed [44, 45]. The CR would be equal to 0. Mu and Pereyra-Rojas [44] recommended performing a consistency analysis whenever the criteria were more than two. The CR for the feasibility scenario was 0 because the CI values obtained from the priority vector was 0.
\nValue of priority vectors were considered as the final relative weight to each one of the variables in this analysis, for determining the optimal locations according to the three priority site scenarios [33, 43]. Here, under the social site scenario, the biomass availability was the most relevant (41.2%), while under the social demand and potential scenarios, the biomass availability was secondary (18.7% relevance for each). The same pattern was found in the demand scenario, where the availability was most relevant (49.6%), followed by the high-energy demand (33.0%). Finally, in the feasibility scenario, where biomass was considered a limiter, the land use, road network, and distance to the electrical distribution network were considered the factors with the greatest weight (31.8%).
\nUsing the three scenarios for determining the best location for an energy production plant based on the wheat residue biomass, a similar behavior was observed in the priority establishment sites (Figure 4). In the social scenario, the optimal locations were dispersed in the central valley of the region, with a greater quantity in the south of the province of Malleco and the north of the province of Cautín, covering a surface of 226,414 ha (Figure 4a). In the feasibility scenario, the availability of the residue biomass was considered as a limiter; therefore, the best sites were clustered in areas similar to the distribution of the residues, which was concentrated in the central area of the region. For a G/CC plant with a minimum biomass requirement of 5536.1 t year−1, the available surface was 54,795 ha. However, for a C/ST plant, with a minimum biomass requirement of 8534.8 t year−1, the available surface was 41,949 ha (Figure 4b). In the high-demand scenario, a similar distribution to that of the feasibility scenario was observed, with a concentration of the optimal areas in the center of the region. The available space was 183,235 ha (Figure 4c).
\nPriority sites for energy plant installation an energy production plant based on the wheat biomass in the Araucanía region obtained by AHP under different scenarios, (a) social scenario; (b) feasibility scenario for C/ST plant with 8534.8 t year−1 biomass as minimum requirement; (c) current demand scenario; and (d) multipurpose priority sites based in three scenarios for installation an energy production plant based on the wheat biomass in the Araucanía region.
Finally, 19 districts that met the requirements for the three scenarios were found. Thus, the installation of the plant may be considered an integrated solution for different types of demand (social, feasibility, and high demand). These districts were Chufquén, Coipué, Colonia Lautaro, Dollinco, General López, Huichahue, La Colmena, La Selva, Manzanaco, Parlamento, Perquenco, Quilquén, Quilquilco, Quino, Quintrilpe, Rehuecoyán, Roble Gaucho, Santa Ana, and Tricauco (Figure 4d).
\nIn this study, the possibility of producing electrical energy using wheat residue biomass was evaluated based on two different combined cycle technologies (C/ST and G/CC), where the biomass was submitted to a thermic process and then generated electricity [2]. These technologies must be economically evaluated to determine their viability in the Araucanía Region. In addition, there are other potential uses for residual biomass. Recently, Azócar et al. [46] evaluated the production of pellets from wheat residue biomass using a roasting process that optimized energy production from this raw material. Therefore, there are multiple alternatives for creating energy from this raw material that should be evaluated to avoid burning these residues and the environmental consequences from these actions [17].
\nThe multi-criteria analysis determined the sites where energy demand was present based on various scenarios. The energy demand contained a distribution in different sectors of the region. The current demand (high demand) was concentrated in the main economic and residential centers of the region, and because the residential demand was prioritized over the industrial demand, the municipalities of Carahue, Cunco, and Temuco had the highest demand. The potential demand was found in the rural zones, where there is a minimal electrical service. These areas are mainly located in the mountain and/or coastal zones, which are far from the city of Temuco, the regional capital. The social demand showed greater distribution in the region, because there are dispersed rural settlements that require energy.
\nThe optimal location for an energy production plant was determined using relevant information, such as the availability of the biomass, road network, etc. The biomass availability was the criterion with the greatest influence on a placement decision in the three scenarios (social, feasibility, and demand). Therefore, in the three scenarios, the optimal locations had a distribution similar to the availability of the biomass. The districts were Chufquén, Coipué, Colonia Lautaro, Dollinco, General López, Huichahue, La Colmena, La Selva, Manzanaco, Parlamento, Perquenco, Quilquén, Quilquilco, Quino, Quintrilpe, Rehuecoyán, Roble Gaucho, Santa Ana, and Tricauco, where the energy-producing plant, using wheat residue biomass, had greater viability because it meets the demand for the three scenarios under evaluation.
\nBovine mastitis is one of the most important bacterial diseases of dairy cattle throughout the world. Mastitis is responsible for major economic losses to the dairy producer and milk processing industry resulting from reduced milk production, alterations in milk composition, discarded milk, increased replacement costs, extra labor, treatment costs, and veterinary services [1]. Annual economic losses due to bovine mastitis are estimated to be $2 billion in the United States [2], $400 million in Canada (Canadian Bovine Mastitis and Milk Quality Research Network-CBMQRN), and $130 million in Australia [3]. Many factors including host, pathogen, and environmental factors influence the development of mastitis; however, inflammation of the mammary gland is usually a consequence of adhesion, invasion, and colonization of the mammary gland by one or more contagious (
Over 135 various microorganisms have been identified from bovine mastitis. The most common bovine mastitis pathogens are classified as contagious and environmental mastitis pathogens [4]. This classification depends upon their distribution in their natural habitat and mode of transmission from their natural habitat to the mammary glands of dairy cows [5]. It is important to mention that all pathogens lists as environmental or contagious may not be strictly environmental or strictly contagious; some of them may transmit both ways. Environmental mastitis pathogens exist in the cow’s environment, and they can cause infection at any time. Environmental mastitis pathogens are difficult to control because they are in the environment of dairy cows and can transmit to the mammary glands at any time, whereas contagious mastitis pathogens exist in the infected udder or on the teat skin and transmit from infected to non-infected udder during milking by milker’s hand or milking machine liners. Environmental mastitis pathogens include a wide range of organisms, including coliform bacteria (
Contagious mastitis pathogens primarily exist in the infected mammary glands or on the cow’s teat skin and transmit from infected to non-infected mammary glands during milking by milker’s hand or milking machine liners.
It is important to mention that all environmental mastitis pathogens may not be strictly environmental, and some of them may transmit both ways (contagious and environmental). However, the vast majority of these organisms are in the environment of dairy cows, and they transmit from these environmental sources to the udder of a cow at any time of the lactation cycle.
\n\n
\n
More recently, coagulase-negative
\n
Coliform bacteria such as
Coagulase-positive
\n
Although the incidence of
\n
Some of surface localized structural components that serve as virulence factors include membrane-bound proteins, which include collagen-binding protein, fibrinogen-binding protein, elastin-binding protein, penicillin-binding protein, and lipoteichoic acid. Similarly, cell wall-bound factors such as peptidoglycan, lipoteichoic acid, teichoic acid, protein A, β-Lactamase, and proteases serve as non-secretory virulence factors. Other cell surface-associated virulence factors include exopolysaccharides, which comprises capsule, slime, and biofilm. Overall,
Surface proteins, such as staphylococcal protein A (SpA), clumping factors A and B (ClfA and ClfB) [69, 70, 71], fibrinogen-binding proteins [72], iron-regulated surface determinants (IsdA, IsdB, and IsdH) [69, 73], fibronectin-binding proteins A and B [74], biofilm associated protein (BAP) and exopolysaccharides (capsule, slime, and biofilms) [75, 76, 77, 78, 79], play roles in
Biofilms are considered an important virulence factor in the pathogenesis of bovine
Some of the known secretory virulence factors are toxins which include staphylococcal enterotoxins, non-enteric exfoliative toxins, toxic shock syndrome toxin 1, leucocidin, and hemolysins (alpha, beta, delta, and gamma) [91, 92]. Similarly, enzymes such as coagulase, staphylokinase, DNAase, phosphatase, lipase, phospholipase, and hyaluronidase serve as virulence factors of
\n
These toxins are heat stable and can resist pasteurization.
Enterotoxins are believed to have a role in the development of mastitis since
In addition to specific virulence factors,
Adhesion is the first step in the formation of biofilm or the invasion of host cells, which protects the bacteria from the host immune system and facilitates chronic infection [124]. Adhesion is dependent on surface proteins called adhesins, which help the bacterium to recognize and attach to host cells. Staphylococci are coated with a wide variety of surface proteins that help them to adhere to host cells and extracellular matrix components. Microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) of the host are the most common surface proteins that are involved in adhesion [124]. The ability to bind to host tissue or the host’s cell surface is a pivotal part of the bacteria’s pathogenicity because adhesion is typically the first step in the invasion and biofilm formation [125, 126].
\nAdhesion to and invasion into epithelial cells [124], intracellular survival in macrophages [127], and epithelial cells allow them to avoid detection by the host immune system and resist treatment with antibiotics [120]. Due to its poor response to treatments,
The mode of transmission from infected mammary glands or colonized udder skin to healthy mammary glands is through contact during milking procedures with milker’s hand, towel, and milking machine [58].
The most important virulence factor of
Mastitis caused by
In general, it is believed that mastitis pathogens gain entrance to the udder through teat opening into the teat canal and from the teat canal into the intramammary area during the reverse flow of milk due to vacuum pressure fluctuation of the milking machine [9]. However, the detailed mechanism of mastitis pathogen colonization of the mammary gland may vary among species of bacteria and the virulence factors associated with particular strain in each species. An example of this is in some cases; it has been shown that
Depending on clinical signs, mastitis can also be divided into clinical and subclinical mastitis. Clinical mastitis is characterized by visible inflammatory changes (abnormalities) in the mammary gland tissue such as redness, swelling, pain, increased heart, and abnormal changes in milk color (watery, bloody, and blood tinged) and consistency (clots or flakes) [9]. Clinical mastitis can be acute, peracute, subacute, or chronic. Acute mastitis is a very rapid inflammatory response characterized by systemic clinical signs which include fever, anorexia, shock, as well as local inflammatory changes in the mammary gland and milk. Peracute mastitis is manifested by a rapid onset of severe inflammation, pain, and systemic symptoms that resulted in a severely sick cow within a short period of time. Subacute mastitis is the most frequently seen form of clinical mastitis characterized by few local signs of mild inflammation in the udder and visible changes in milk such as small clots. Chronic mastitis is a long-term recurring, persistent case of mastitis that may show few symptoms of mastitis between repeated occasional flare-ups of the disease where signs are visible and can continue over periods of several months. Chronic mastitis often leads to irreversible damage to the udder from the repeated occurrences of the inflammation, and often these cows are culled.
\nSubclinical mastitis is the inflammation of the mammary gland that does not create visible changes in the milk or the udder. Subclinical mastitis is an infection of mammary gland characterized by non-visible inflammatory changes such as a high somatic cell count coupled with shedding of causative bacteria through milk [9]. During this inflammatory process, the milk samples showed a rapid increase of somatic cells, characterized by increased number of neutrophils in the secretion [146, 148]. Despite increased recruitment of somatic cells into infected mammary glands, evidenced by an increased number of neutrophils, infection usually does not clear but became subclinical. Intramammary infections during early lactation may become acute clinical mastitis characterized by gangrene development due congestion and thrombosis (blockage) of blood supply to the tissue but most new infection during late lactation or dry period become acute or chronic mastitis [149, 150].
\nThe increase in somatic cell count during subclinical infections leads to a decrease in useful components in the milk, such as lactose and casein [151]. Lactose is the sugar found in milk, and casein is one of the major proteins in milk and decreases in these two components affect the quality and quantity of milk yield [9]. During mastitis, there is an increase in lipase and plasmin, which have a detrimental effect on the quantity and quality of milk due to the breakdown of milk fat and casein [9]. Subclinical infections can reduce milk production by 10–12% when just one-quarter is infected [152]. These subclinical infections cause some of the greatest unseen economic [20] losses because of their detrimental impact on production and milk quality without showing visible signs of infection [152].
\nThere are host-, pathogen-, and environmental-related risk factors that predispose dairy cows to mastitis. The host risk factors include age (parity), stage of lactation, somatic cell count, breed, the anatomy of the mammary glands/morphology of udder and teat (diameter of teat canal and conformation of the udder), and immune competence (immunity) [153] (Figure 1). The environmental risk factors include the proper functioning status of milking machine, udder trauma, sanitation, climate, nutrition, management, season, and housing condition [154] (Figure 1). The pathogen risk factors include type (bacteria, fungi, yeast, and algae), number (large number and small number), virulence (highly, moderate, or less virulent), frequency of exposure (dirty farm floor, dirty milking machine, and dirty teat drying towels frequently expose to pathogen; clean floor, clean milking machine, and clean teat drying towels less exposure to pathogens), ability to resist flushing out of the glands by milk (ability to adhere or attach to and invade or internalize into mammary epithelial cells), zoonotic (transmit from cow to human or vice versa) potential, and resistance to antimicrobials [4] (Figure 1). The warm, humid, and moist climate favors the growth of bacteria and increases the chances of intramammary infection (IMI) and mastitis development [154]. The incidence of mastitis varies from farm to farm due to the combined effects of these different factors that increase the risk of disease development.
\nRisk factors for mastitis. SA,
Dairy cows are highly susceptible to IMI during the early dry period due to increased colonization of teat skin with bacteria. Bacterial colonization of teat increases during the early dry period because of an absence of hygienic milking practices including pre-milking washing and drying of teats [155], as well as pre- and post-milking teat dipping in antiseptic solutions [156, 157] that are known to reduce teat end colonization and infection. An udder infected during the early dry period usually manifests clinical mastitis during the transition period because of increased production of parturition inducing immunosuppressive hormones [158, 159], negative energy balance [160], and physical stress during calving [161].
\nMastitis is increasingly becoming a public health concern due to the ability of the causative bacterial pathogens and/or their products, such as enterotoxins, to enter the food supply and cause foodborne diseases [109, 162], especially through the consumption of raw milk [29] and undercooked meat of culled dairy cows due to chronic mastitis that are usually sold to the slaughter (abattoir) for meat consumption. The Center for Disease Control (CDC) estimated that roughly 48 million people in the United States a year become sick from foodborne diseases [163]. Foodborne pathogens have been detected in bulk tank milk in multiple studies [164, 165, 166, 167]. These authors found that the number of foodborne pathogens detected in bulk tank milk vary with location, management practices, hygiene, and number of animals on the farm [165]. Similarly, a study on bulk tank milk from east Tennessee and southwest Virginia by Rohrbach et al. [168] showed that 32.5% of the samples analyzed contained one or more foodborne pathogens. Even dairy producers who used proper hygienic milking practices, pre- and post-milking teat disinfectant and antibiotic dry cow therapy, had foodborne pathogens in their bulk tank milk [164]. The isolation of these foodborne pathogens from bulk tank milk samples across the United States demonstrate the threat that mastitis pathogens and zoonotic mastitis causing pathogens create on public health if raw milk is consumed or if these pathogens make it through processing.
\nBovine mastitis is the most important multifactorial disease of dairy cattle throughout the world. Mastitis is responsible for huge economic losses to the dairy producers and milk processing industry due to reduced milk production, alterations in milk composition, discarded milk, increased replacement costs, extra labor, treatment costs, and veterinary services. Many factors including pathogen, host, and environment can influence the development of mastitis. Mastitis, the inflammation of the mammary gland is usually a consequence of adhesion, invasion, and colonization of the mammary gland by one or more mastitis pathogens such as
IntechOpen - where academia and industry create content with global impact
",metaTitle:"Team",metaDescription:"Advancing discovery in Open Access for the scientists by the scientist",metaKeywords:null,canonicalURL:"page/team",contentRaw:'[{"type":"htmlEditorComponent","content":"Our business values are based on those any scientist applies to their research. We have created a culture of respect and collaboration within a relaxed, friendly and progressive atmosphere, while maintaining academic rigour.
\\n\\nCo-founded by Alex Lazinica and Vedran Kordic: “We are passionate about the advancement of science. As Ph.D. researchers in Vienna, we found it difficult to access the scholarly research we needed. We created IntechOpen with the specific aim of putting the academic needs of the global research community before the business interests of publishers. Our Team is now a global one and includes highly-renowned scientists and publishers, as well as experts in disseminating your research.”
\\n\\nBut, one thing we have in common is -- we are all scientists at heart!
\\n\\nSara Uhac, COO
\\n\\nSara Uhac was appointed Managing Director of IntechOpen at the beginning of 2014. She directs and controls the company’s operations. Sara joined IntechOpen in 2010 as Head of Journal Publishing, a new strategically underdeveloped department at that time. After obtaining a Master's degree in Media Management, she completed her Ph.D. at the University of Lugano, Switzerland. She holds a BA in Financial Market Management from the Bocconi University in Milan, Italy, where she started her career in the American publishing house Condé Nast and further collaborated with the UK-based publishing company Time Out. Sara was awarded a professional degree in Publishing from Yale University (2012). She is a member of the professional branch association of "Publishers, Designers and Graphic Artists" at the Croatian Chamber of Commerce.
\\n\\nAdrian Assad De Marco
\\n\\nAdrian Assad De Marco joined the company as a Director in 2017. With his extensive experience in management, acquired while working for regional and global leaders, he took over direction and control of all the company's publishing processes. Adrian holds a degree in Economy and Management from the University of Zagreb, School of Economics, Croatia. A former sportsman, he continually strives to develop his skills through professional courses and specializations such as NLP (Neuro-linguistic programming).
\\n\\nDr Alex Lazinica
\\n\\nAlex Lazinica is co-founder and Board member of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his Ph.D. in Robotics at the Vienna University of Technology. There, he worked as a robotics researcher with the university's Intelligent Manufacturing Systems Group, as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and, most importantly, co-founded and built the International Journal of Advanced Robotic Systems, the world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career since it proved to be the pathway to the foundation of IntechOpen with its focus on addressing academic researchers’ needs. Alex personifies many of IntechOpen´s key values, including the commitment to developing mutual trust, openness, and a spirit of entrepreneurialism. Today, his focus is on defining the growth and development strategy for the company.
\\n"}]'},components:[{type:"htmlEditorComponent",content:"Our business values are based on those any scientist applies to their research. We have created a culture of respect and collaboration within a relaxed, friendly and progressive atmosphere, while maintaining academic rigour.
\n\nCo-founded by Alex Lazinica and Vedran Kordic: “We are passionate about the advancement of science. As Ph.D. researchers in Vienna, we found it difficult to access the scholarly research we needed. We created IntechOpen with the specific aim of putting the academic needs of the global research community before the business interests of publishers. Our Team is now a global one and includes highly-renowned scientists and publishers, as well as experts in disseminating your research.”
\n\nBut, one thing we have in common is -- we are all scientists at heart!
\n\nSara Uhac, COO
\n\nSara Uhac was appointed Managing Director of IntechOpen at the beginning of 2014. She directs and controls the company’s operations. Sara joined IntechOpen in 2010 as Head of Journal Publishing, a new strategically underdeveloped department at that time. After obtaining a Master's degree in Media Management, she completed her Ph.D. at the University of Lugano, Switzerland. She holds a BA in Financial Market Management from the Bocconi University in Milan, Italy, where she started her career in the American publishing house Condé Nast and further collaborated with the UK-based publishing company Time Out. Sara was awarded a professional degree in Publishing from Yale University (2012). She is a member of the professional branch association of "Publishers, Designers and Graphic Artists" at the Croatian Chamber of Commerce.
\n\nAdrian Assad De Marco
\n\nAdrian Assad De Marco joined the company as a Director in 2017. With his extensive experience in management, acquired while working for regional and global leaders, he took over direction and control of all the company's publishing processes. Adrian holds a degree in Economy and Management from the University of Zagreb, School of Economics, Croatia. A former sportsman, he continually strives to develop his skills through professional courses and specializations such as NLP (Neuro-linguistic programming).
\n\nDr Alex Lazinica
\n\nAlex Lazinica is co-founder and Board member of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his Ph.D. in Robotics at the Vienna University of Technology. There, he worked as a robotics researcher with the university's Intelligent Manufacturing Systems Group, as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and, most importantly, co-founded and built the International Journal of Advanced Robotic Systems, the world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career since it proved to be the pathway to the foundation of IntechOpen with its focus on addressing academic researchers’ needs. Alex personifies many of IntechOpen´s key values, including the commitment to developing mutual trust, openness, and a spirit of entrepreneurialism. Today, his focus is on defining the growth and development strategy for the company.
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Nutrition",value:20,count:2},{group:"subseries",caption:"Animal Reproductive Biology and Technology",value:28,count:3},{group:"subseries",caption:"Animal Science",value:19,count:5}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:2},{group:"publicationYear",caption:"2021",value:2021,count:3},{group:"publicationYear",caption:"2020",value:2020,count:3},{group:"publicationYear",caption:"2019",value:2019,count:1},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:302,paginationItems:[{id:"198499",title:"Dr.",name:"Daniel",middleName:null,surname:"Glossman-Mitnik",slug:"daniel-glossman-mitnik",fullName:"Daniel Glossman-Mitnik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/198499/images/system/198499.jpeg",biography:"Dr. Daniel Glossman-Mitnik is currently a Titular Researcher at the Centro de Investigación en Materiales Avanzados (CIMAV), Chihuahua, Mexico, as well as a National Researcher of Level III at the Consejo Nacional de Ciencia y Tecnología, Mexico. His research interest focuses on computational chemistry and molecular modeling of diverse systems of pharmacological, food, and alternative energy interests by resorting to DFT and Conceptual DFT. He has authored a coauthored more than 255 peer-reviewed papers, 32 book chapters, and 2 edited books. He has delivered speeches at many international and domestic conferences. He serves as a reviewer for more than eighty international journals, books, and research proposals as well as an editor for special issues of renowned scientific journals.",institutionString:"Centro de Investigación en Materiales Avanzados",institution:{name:"Centro de Investigación en Materiales Avanzados",country:{name:"Mexico"}}},{id:"76477",title:"Prof.",name:"Mirza",middleName:null,surname:"Hasanuzzaman",slug:"mirza-hasanuzzaman",fullName:"Mirza Hasanuzzaman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/76477/images/system/76477.png",biography:"Dr. Mirza Hasanuzzaman is a Professor of Agronomy at Sher-e-Bangla Agricultural University, Bangladesh. He received his Ph.D. in Plant Stress Physiology and Antioxidant Metabolism from Ehime University, Japan, with a scholarship from the Japanese Government (MEXT). Later, he completed his postdoctoral research at the Center of Molecular Biosciences, University of the Ryukyus, Japan, as a recipient of the Japan Society for the Promotion of Science (JSPS) postdoctoral fellowship. He was also the recipient of the Australian Government Endeavour Research Fellowship for postdoctoral research as an adjunct senior researcher at the University of Tasmania, Australia. Dr. Hasanuzzaman’s current work is focused on the physiological and molecular mechanisms of environmental stress tolerance. Dr. Hasanuzzaman has published more than 150 articles in peer-reviewed journals. He has edited ten books and written more than forty book chapters on important aspects of plant physiology, plant stress tolerance, and crop production. According to Scopus, Dr. Hasanuzzaman’s publications have received more than 10,500 citations with an h-index of 53. He has been named a Highly Cited Researcher by Clarivate. He is an editor and reviewer for more than fifty peer-reviewed international journals and was a recipient of the “Publons Peer Review Award” in 2017, 2018, and 2019. He has been honored by different authorities for his outstanding performance in various fields like research and education, and he has received the World Academy of Science Young Scientist Award (2014) and the University Grants Commission (UGC) Award 2018. He is a fellow of the Bangladesh Academy of Sciences (BAS) and the Royal Society of Biology.",institutionString:"Sher-e-Bangla Agricultural University",institution:{name:"Sher-e-Bangla Agricultural University",country:{name:"Bangladesh"}}},{id:"187859",title:"Prof.",name:"Kusal",middleName:"K.",surname:"Das",slug:"kusal-das",fullName:"Kusal Das",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBDeQAO/Profile_Picture_1623411145568",biography:"Kusal K. Das is a Distinguished Chair Professor of Physiology, Shri B. M. Patil Medical College and Director, Centre for Advanced Medical Research (CAMR), BLDE (Deemed to be University), Vijayapur, Karnataka, India. Dr. Das did his M.S. and Ph.D. in Human Physiology from the University of Calcutta, Kolkata. His area of research is focused on understanding of molecular mechanisms of heavy metal activated low oxygen sensing pathways in vascular pathophysiology. He has invented a new method of estimation of serum vitamin E. His expertise in critical experimental protocols on vascular functions in experimental animals was well documented by his quality of publications. He was a Visiting Professor of Medicine at University of Leeds, United Kingdom (2014-2016) and Tulane University, New Orleans, USA (2017). For his immense contribution in medical research Ministry of Science and Technology, Government of India conferred him 'G.P. Chatterjee Memorial Research Prize-2019” and he is also the recipient of 'Dr.Raja Ramanna State Scientist Award 2015” by Government of Karnataka. He is a Fellow of the Royal Society of Biology (FRSB), London and Honorary Fellow of Karnataka Science and Technology Academy, Department of Science and Technology, Government of Karnataka.",institutionString:"BLDE (Deemed to be University), India",institution:null},{id:"243660",title:"Dr.",name:"Mallanagouda Shivanagouda",middleName:null,surname:"Biradar",slug:"mallanagouda-shivanagouda-biradar",fullName:"Mallanagouda Shivanagouda Biradar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243660/images/system/243660.jpeg",biography:"M. S. Biradar is Vice Chancellor and Professor of Medicine of\nBLDE (Deemed to be University), Vijayapura, Karnataka, India.\nHe obtained his MD with a gold medal in General Medicine and\nhas devoted himself to medical teaching, research, and administrations. He has also immensely contributed to medical research\non vascular medicine, which is reflected by his numerous publications including books and book chapters. Professor Biradar was\nalso Visiting Professor at Tulane University School of Medicine, New Orleans, USA.",institutionString:"BLDE (Deemed to be University)",institution:{name:"BLDE University",country:{name:"India"}}},{id:"289796",title:"Dr.",name:"Swastika",middleName:null,surname:"Das",slug:"swastika-das",fullName:"Swastika Das",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/289796/images/system/289796.jpeg",biography:"Swastika N. Das is Professor of Chemistry at the V. P. Dr. P. G.\nHalakatti College of Engineering and Technology, BLDE (Deemed\nto be University), Vijayapura, Karnataka, India. She obtained an\nMSc, MPhil, and PhD in Chemistry from Sambalpur University,\nOdisha, India. Her areas of research interest are medicinal chemistry, chemical kinetics, and free radical chemistry. She is a member\nof the investigators who invented a new modified method of estimation of serum vitamin E. She has authored numerous publications including book\nchapters and is a mentor of doctoral curriculum at her university.",institutionString:"BLDEA’s V.P.Dr.P.G.Halakatti College of Engineering & Technology",institution:{name:"BLDE University",country:{name:"India"}}},{id:"248459",title:"Dr.",name:"Akikazu",middleName:null,surname:"Takada",slug:"akikazu-takada",fullName:"Akikazu Takada",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248459/images/system/248459.png",biography:"Akikazu Takada was born in Japan, 1935. After graduation from\nKeio University School of Medicine and finishing his post-graduate studies, he worked at Roswell Park Memorial Institute NY,\nUSA. He then took a professorship at Hamamatsu University\nSchool of Medicine. In thrombosis studies, he found the SK\npotentiator that enhances plasminogen activation by streptokinase. He is very much interested in simultaneous measurements\nof fatty acids, amino acids, and tryptophan degradation products. By using fatty\nacid analyses, he indicated that plasma levels of trans-fatty acids of old men were\nfar higher in the US than Japanese men. . He also showed that eicosapentaenoic acid\n(EPA) and docosahexaenoic acid (DHA) levels are higher, and arachidonic acid\nlevels are lower in Japanese than US people. By using simultaneous LC/MS analyses\nof plasma levels of tryptophan metabolites, he recently found that plasma levels of\nserotonin, kynurenine, or 5-HIAA were higher in patients of mono- and bipolar\ndepression, which are significantly different from observations reported before. In\nview of recent reports that plasma tryptophan metabolites are mainly produced by\nmicrobiota. He is now working on the relationships between microbiota and depression or autism.",institutionString:"Hamamatsu University School of Medicine",institution:{name:"Hamamatsu University School of Medicine",country:{name:"Japan"}}},{id:"137240",title:"Prof.",name:"Mohammed",middleName:null,surname:"Khalid",slug:"mohammed-khalid",fullName:"Mohammed Khalid",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/137240/images/system/137240.png",biography:"Mohammed Khalid received his B.S. degree in chemistry in 2000 and Ph.D. degree in physical chemistry in 2007 from the University of Khartoum, Sudan. He moved to School of Chemistry, Faculty of Science, University of Sydney, Australia in 2009 and joined Dr. Ron Clarke as a postdoctoral fellow where he worked on the interaction of ATP with the phosphoenzyme of the Na+/K+-ATPase and dual mechanisms of allosteric acceleration of the Na+/K+-ATPase by ATP; then he went back to Department of Chemistry, University of Khartoum as an assistant professor, and in 2014 he was promoted as an associate professor. In 2011, he joined the staff of Department of Chemistry at Taif University, Saudi Arabia, where he is currently an assistant professor. His research interests include the following: P-Type ATPase enzyme kinetics and mechanisms, kinetics and mechanisms of redox reactions, autocatalytic reactions, computational enzyme kinetics, allosteric acceleration of P-type ATPases by ATP, exploring of allosteric sites of ATPases, and interaction of ATP with ATPases located in cell membranes.",institutionString:"Taif University",institution:{name:"Taif University",country:{name:"Saudi Arabia"}}},{id:"63810",title:"Prof.",name:"Jorge",middleName:null,surname:"Morales-Montor",slug:"jorge-morales-montor",fullName:"Jorge Morales-Montor",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/63810/images/system/63810.png",biography:"Dr. Jorge Morales-Montor was recognized with the Lola and Igo Flisser PUIS Award for best graduate thesis at the national level in the field of parasitology. He received a fellowship from the Fogarty Foundation to perform postdoctoral research stay at the University of Georgia. He has 153 journal articles to his credit. He has also edited several books and published more than fifty-five book chapters. He is a member of the Mexican Academy of Sciences, Latin American Academy of Sciences, and the National Academy of Medicine. He has received more than thirty-five awards and has supervised numerous bachelor’s, master’s, and Ph.D. students. Dr. Morales-Montor is the past president of the Mexican Society of Parasitology.",institutionString:"National Autonomous University of Mexico",institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"217215",title:"Dr.",name:"Palash",middleName:null,surname:"Mandal",slug:"palash-mandal",fullName:"Palash Mandal",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/217215/images/system/217215.jpeg",biography:null,institutionString:"Charusat University",institution:null},{id:"49739",title:"Dr.",name:"Leszek",middleName:null,surname:"Szablewski",slug:"leszek-szablewski",fullName:"Leszek Szablewski",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49739/images/system/49739.jpg",biography:"Leszek Szablewski is a professor of medical sciences. He received his M.S. in the Faculty of Biology from the University of Warsaw and his PhD degree from the Institute of Experimental Biology Polish Academy of Sciences. He habilitated in the Medical University of Warsaw, and he obtained his degree of Professor from the President of Poland. Professor Szablewski is the Head of Chair and Department of General Biology and Parasitology, Medical University of Warsaw. Professor Szablewski has published over 80 peer-reviewed papers in journals such as Journal of Alzheimer’s Disease, Biochim. Biophys. Acta Reviews of Cancer, Biol. Chem., J. Biomed. Sci., and Diabetes/Metabol. Res. Rev, Endocrine. He is the author of two books and four book chapters. He has edited four books, written 15 scripts for students, is the ad hoc reviewer of over 30 peer-reviewed journals, and editorial member of peer-reviewed journals. Prof. Szablewski’s research focuses on cell physiology, genetics, and pathophysiology. He works on the damage caused by lack of glucose homeostasis and changes in the expression and/or function of glucose transporters due to various diseases. He has given lectures, seminars, and exercises for students at the Medical University.",institutionString:"Medical University of Warsaw",institution:{name:"Medical University of Warsaw",country:{name:"Poland"}}},{id:"173123",title:"Dr.",name:"Maitham",middleName:null,surname:"Khajah",slug:"maitham-khajah",fullName:"Maitham Khajah",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/173123/images/system/173123.jpeg",biography:"Dr. Maitham A. Khajah received his degree in Pharmacy from Faculty of Pharmacy, Kuwait University, in 2003 and obtained his PhD degree in December 2009 from the University of Calgary, Canada (Gastrointestinal Science and Immunology). Since January 2010 he has been assistant professor in Kuwait University, Faculty of Pharmacy, Department of Pharmacology and Therapeutics. His research interest are molecular targets for the treatment of inflammatory bowel disease (IBD) and the mechanisms responsible for immune cell chemotaxis. He cosupervised many students for the MSc Molecular Biology Program, College of Graduate Studies, Kuwait University. Ever since joining Kuwait University in 2010, he got various grants as PI and Co-I. He was awarded the Best Young Researcher Award by Kuwait University, Research Sector, for the Year 2013–2014. He was a member in the organizing committee for three conferences organized by Kuwait University, Faculty of Pharmacy, as cochair and a member in the scientific committee (the 3rd, 4th, and 5th Kuwait International Pharmacy Conference).",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"195136",title:"Dr.",name:"Aya",middleName:null,surname:"Adel",slug:"aya-adel",fullName:"Aya Adel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/195136/images/system/195136.jpg",biography:"Dr. Adel works as an Assistant Lecturer in the unit of Phoniatrics, Department of Otolaryngology, Ain Shams University in Cairo, Egypt. Dr. Adel is especially interested in joint attention and its impairment in autism spectrum disorder",institutionString:"Ain Shams University",institution:{name:"Ain Shams University",country:{name:"Egypt"}}},{id:"94911",title:"Dr.",name:"Boulenouar",middleName:null,surname:"Mesraoua",slug:"boulenouar-mesraoua",fullName:"Boulenouar Mesraoua",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94911/images/system/94911.png",biography:"Dr Boulenouar Mesraoua is the Associate Professor of Clinical Neurology at Weill Cornell Medical College-Qatar and a Consultant Neurologist at Hamad Medical Corporation at the Neuroscience Department; He graduated as a Medical Doctor from the University of Oran, Algeria; he then moved to Belgium, the City of Liege, for a Residency in Internal Medicine and Neurology at Liege University; after getting the Belgian Board of Neurology (with high marks), he went to the National Hospital for Nervous Diseases, Queen Square, London, United Kingdom for a fellowship in Clinical Neurophysiology, under Pr Willison ; Dr Mesraoua had also further training in Epilepsy and Continuous EEG Monitoring for two years (from 2001-2003) in the Neurophysiology department of Zurich University, Switzerland, under late Pr Hans Gregor Wieser ,an internationally known epileptologist expert. \n\nDr B. Mesraoua is the Director of the Neurology Fellowship Program at the Neurology Section and an active member of the newly created Comprehensive Epilepsy Program at Hamad General Hospital, Doha, Qatar; he is also Assistant Director of the Residency Program at the Qatar Medical School. \nDr B. Mesraoua's main interests are Epilepsy, Multiple Sclerosis, and Clinical Neurology; He is the Chairman and the Organizer of the well known Qatar Epilepsy Symposium, he is running yearly for the past 14 years and which is considered a landmark in the Gulf region; He has also started last year , together with other epileptologists from Qatar, the region and elsewhere, a yearly International Epilepsy School Course, which was attended by many neurologists from the Area.\n\nInternationally, Dr Mesraoua is an active and elected member of the Commission on Eastern Mediterranean Region (EMR ) , a regional branch of the International League Against Epilepsy (ILAE), where he represents the Middle East and North Africa(MENA ) and where he holds the position of chief of the Epilepsy Epidemiology Section; Dr Mesraoua is a member of the American Academy of Neurology, the Europeen Academy of Neurology and the American Epilepsy Society.\n\nDr Mesraoua's main objectives are to encourage frequent gathering of the epileptologists/neurologists from the MENA region and the rest of the world, promote Epilepsy Teaching in the MENA Region, and encourage multicenter studies involving neurologists and epileptologists in the MENA region, particularly epilepsy epidemiological studies. \n\nDr. Mesraoua is the recipient of two research Grants, as the Lead Principal Investigator (750.000 USD and 250.000 USD) from the Qatar National Research Fund (QNRF) and the Hamad Hospital Internal Research Grant (IRGC), on the following topics : “Continuous EEG Monitoring in the ICU “ and on “Alpha-lactoalbumin , proof of concept in the treatment of epilepsy” .Dr Mesraoua is a reviewer for the journal \"seizures\" (Europeen Epilepsy Journal ) as well as dove journals ; Dr Mesraoua is the author and co-author of many peer reviewed publications and four book chapters in the field of Epilepsy and Clinical Neurology",institutionString:"Weill Cornell Medical College in Qatar",institution:{name:"Weill Cornell Medical College in Qatar",country:{name:"Qatar"}}},{id:"282429",title:"Prof.",name:"Covanis",middleName:null,surname:"Athanasios",slug:"covanis-athanasios",fullName:"Covanis Athanasios",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/282429/images/system/282429.jpg",biography:null,institutionString:"Neurology-Neurophysiology Department of the Children Hospital Agia Sophia",institution:null},{id:"190980",title:"Prof.",name:"Marwa",middleName:null,surname:"Mahmoud Saleh",slug:"marwa-mahmoud-saleh",fullName:"Marwa Mahmoud Saleh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/190980/images/system/190980.jpg",biography:"Professor Marwa Mahmoud Saleh is a doctor of medicine and currently works in the unit of Phoniatrics, Department of Otolaryngology, Ain Shams University in Cairo, Egypt. She got her doctoral degree in 1991 and her doctoral thesis was accomplished in the University of Iowa, United States. Her publications covered a multitude of topics as videokymography, cochlear implants, stuttering, and dysphagia. She has lectured Egyptian phonology for many years. Her recent research interest is joint attention in autism.",institutionString:"Ain Shams University",institution:{name:"Ain Shams University",country:{name:"Egypt"}}},{id:"259190",title:"Dr.",name:"Syed Ali Raza",middleName:null,surname:"Naqvi",slug:"syed-ali-raza-naqvi",fullName:"Syed Ali Raza Naqvi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259190/images/system/259190.png",biography:"Dr. Naqvi is a radioanalytical chemist and is working as an associate professor of analytical chemistry in the Department of Chemistry, Government College University, Faisalabad, Pakistan. Advance separation techniques, nuclear analytical techniques and radiopharmaceutical analysis are the main courses that he is teaching to graduate and post-graduate students. In the research area, he is focusing on the development of organic- and biomolecule-based radiopharmaceuticals for diagnosis and therapy of infectious and cancerous diseases. Under the supervision of Dr. Naqvi, three students have completed their Ph.D. degrees and 41 students have completed their MS degrees. He has completed three research projects and is currently working on 2 projects entitled “Radiolabeling of fluoroquinolone derivatives for the diagnosis of deep-seated bacterial infections” and “Radiolabeled minigastrin peptides for diagnosis and therapy of NETs”. He has published about 100 research articles in international reputed journals and 7 book chapters. Pakistan Institute of Nuclear Science & Technology (PINSTECH) Islamabad, Punjab Institute of Nuclear Medicine (PINM), Faisalabad and Institute of Nuclear Medicine and Radiology (INOR) Abbottabad are the main collaborating institutes.",institutionString:"Government College University",institution:{name:"Government College University, Faisalabad",country:{name:"Pakistan"}}},{id:"58390",title:"Dr.",name:"Gyula",middleName:null,surname:"Mozsik",slug:"gyula-mozsik",fullName:"Gyula Mozsik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/58390/images/system/58390.png",biography:"Gyula Mózsik MD, Ph.D., ScD (med), is an emeritus professor of Medicine at the First Department of Medicine, Univesity of Pécs, Hungary. He was head of this department from 1993 to 2003. His specializations are medicine, gastroenterology, clinical pharmacology, clinical nutrition, and dietetics. His research fields are biochemical pharmacological examinations in the human gastrointestinal (GI) mucosa, mechanisms of retinoids, drugs, capsaicin-sensitive afferent nerves, and innovative pharmacological, pharmaceutical, and nutritional (dietary) research in humans. He has published about 360 peer-reviewed papers, 197 book chapters, 692 abstracts, 19 monographs, and has edited 37 books. He has given about 1120 regular and review lectures. He has organized thirty-eight national and international congresses and symposia. He is the founder of the International Conference on Ulcer Research (ICUR); International Union of Pharmacology, Gastrointestinal Section (IUPHAR-GI); Brain-Gut Society symposiums, and gastrointestinal cytoprotective symposiums. He received the Andre Robert Award from IUPHAR-GI in 2014. Fifteen of his students have been appointed as full professors in Egypt, Cuba, and Hungary.",institutionString:"University of Pécs",institution:{name:"University of Pecs",country:{name:"Hungary"}}},{id:"277367",title:"M.Sc.",name:"Daniel",middleName:"Martin",surname:"Márquez López",slug:"daniel-marquez-lopez",fullName:"Daniel Márquez López",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/277367/images/7909_n.jpg",biography:"Msc Daniel Martin Márquez López has a bachelor degree in Industrial Chemical Engineering, a Master of science degree in the same área and he is a PhD candidate for the Instituto Politécnico Nacional. His Works are realted to the Green chemistry field, biolubricants, biodiesel, transesterification reactions for biodiesel production and the manipulation of oils for therapeutic purposes.",institutionString:null,institution:{name:"Instituto Politécnico Nacional",country:{name:"Mexico"}}},{id:"196544",title:"Prof.",name:"Angel",middleName:null,surname:"Catala",slug:"angel-catala",fullName:"Angel Catala",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/196544/images/system/196544.jpg",biography:"Angel Catalá studied chemistry at Universidad Nacional de La Plata, Argentina, where he received a Ph.D. in Chemistry (Biological Branch) in 1965. From 1964 to 1974, he worked as an Assistant in Biochemistry at the School of Medicine at the same university. From 1974 to 1976, he was a fellow of the National Institutes of Health (NIH) at the University of Connecticut, Health Center, USA. From 1985 to 2004, he served as a Full Professor of Biochemistry at the Universidad Nacional de La Plata. He is a member of the National Research Council (CONICET), Argentina, and the Argentine Society for Biochemistry and Molecular Biology (SAIB). His laboratory has been interested for many years in the lipid peroxidation of biological membranes from various tissues and different species. Dr. Catalá has directed twelve doctoral theses, published more than 100 papers in peer-reviewed journals, several chapters in books, and edited twelve books. He received awards at the 40th International Conference Biochemistry of Lipids 1999 in Dijon, France. He is the winner of the Bimbo Pan-American Nutrition, Food Science and Technology Award 2006 and 2012, South America, Human Nutrition, Professional Category. In 2006, he won the Bernardo Houssay award in pharmacology, in recognition of his meritorious works of research. Dr. Catalá belongs to the editorial board of several journals including Journal of Lipids; International Review of Biophysical Chemistry; Frontiers in Membrane Physiology and Biophysics; World Journal of Experimental Medicine and Biochemistry Research International; World Journal of Biological Chemistry, Diabetes, and the Pancreas; International Journal of Chronic Diseases & Therapy; and International Journal of Nutrition. He is the co-editor of The Open Biology Journal and associate editor for Oxidative Medicine and Cellular Longevity.",institutionString:"Universidad Nacional de La Plata",institution:{name:"National University of La Plata",country:{name:"Argentina"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",slug:"francisco-javier-martin-romero",fullName:"Francisco Javier Martin-Romero",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",biography:"Francisco Javier Martín-Romero (Javier) is a Professor of Biochemistry and Molecular Biology at the University of Extremadura, Spain. He is also a group leader at the Biomarkers Institute of Molecular Pathology. Javier received his Ph.D. in 1998 in Biochemistry and Biophysics. At the National Cancer Institute (National Institute of Health, Bethesda, MD) he worked as a research associate on the molecular biology of selenium and its role in health and disease. After postdoctoral collaborations with Carlos Gutierrez-Merino (University of Extremadura, Spain) and Dario Alessi (University of Dundee, UK), he established his own laboratory in 2008. 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