Elastography methods used for the liver.
\\n\\n
More than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\\n\\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\\n\\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\\n\\nAdditionally, each book published by IntechOpen contains original content and research findings.
\\n\\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\\n\\n\\n\\n
\\n"}]',published:!0,mainMedia:{caption:"IntechOpen Maintains",originalUrl:"/media/original/113"}},components:[{type:"htmlEditorComponent",content:'
Simba Information has released its Open Access Book Publishing 2020 - 2024 report and has again identified IntechOpen as the world’s largest Open Access book publisher by title count.
\n\nSimba Information is a leading provider for market intelligence and forecasts in the media and publishing industry. The report, published every year, provides an overview and financial outlook for the global professional e-book publishing market.
\n\nIntechOpen, De Gruyter, and Frontiers are the largest OA book publishers by title count, with IntechOpen coming in at first place with 5,101 OA books published, a good 1,782 titles ahead of the nearest competitor.
\n\nSince the first Open Access Book Publishing report published in 2016, IntechOpen has held the top stop each year.
\n\n\n\nMore than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\n\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\n\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\n\nAdditionally, each book published by IntechOpen contains original content and research findings.
\n\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\n\n\n\n
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"3303",leadTitle:null,fullTitle:"Recent Advances in the Field of Ventricular Assist Devices",title:"Recent Advances in the Field of Ventricular Assist Devices",subtitle:null,reviewType:"peer-reviewed",abstract:"Recent Advances in the Field of Ventricular Assist Devices covers recent various advances and developments relating to ventricular assist devices and their diverse complications. Firstly, we overview recent technical advances as well as current indications, clinical outcomes, and countermeasures against complications, and furthermore, the latest techniques to identify clinical effectiveness at the patient’s bedside. Secondly, we elucidate the current status of countermeasures against gastrointestinal bleeding, and current research on allosensitization during the usage of continuous flow pump. Finally, we explore the possibility of a new adjunct therapy in combination with ventricular assist devices. We hope that this book will provide valuable and up-to-date information on research and clinical use of ventricular assist devices.",isbn:null,printIsbn:"978-953-51-1111-5",pdfIsbn:"978-953-51-7142-3",doi:"10.5772/46016",price:119,priceEur:129,priceUsd:155,slug:"recent-advances-in-the-field-of-ventricular-assist-devices",numberOfPages:104,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"52b99c6d5965dd8eeac1ae080bb70567",bookSignature:"Kazuo Komamura",publishedDate:"May 8th 2013",coverURL:"https://cdn.intechopen.com/books/images_new/3303.jpg",numberOfDownloads:10129,numberOfWosCitations:4,numberOfCrossrefCitations:1,numberOfCrossrefCitationsByBook:1,numberOfDimensionsCitations:9,numberOfDimensionsCitationsByBook:1,hasAltmetrics:0,numberOfTotalCitations:14,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 17th 2012",dateEndSecondStepPublish:"May 8th 2012",dateEndThirdStepPublish:"August 12th 2012",dateEndFourthStepPublish:"November 10th 2012",dateEndFifthStepPublish:"December 10th 2012",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"19651",title:"Dr.",name:"Kazuo",middleName:null,surname:"Komamura",slug:"kazuo-komamura",fullName:"Kazuo Komamura",profilePictureURL:"https://mts.intechopen.com/storage/users/19651/images/3723_n.jpg",biography:"Professor Kazuo Komamura received his medical degree from Osaka University School of Medicine, Japan in 1983. He was trained in Coronary Care Unit, Osaka Police Hospital, Japan. Then, he went abroad to study cellular and molecular mechanisms of heart failure at Prof. Stephen Vatner\\'s Laboratory in Cardiovascular Medicine, Harvard Medical School, U.S.A. Coming back to Japan, he was promoted to the Head, Laboratory of Cardiac Dynamics, National Cerebral and Cardiovascular Centre. In 2008, he became a Professor of Pharmaceutical Sciences, Hyogo University of Health Sciences. Currently, he is working as the Director of Osaka Infirmary, Takeda Pharmaceutical, Company Limited as well as an Adjunct Assistant Professor, Cardiovascular Division, Hyogo College of Medicine, Japan. His research focus is on the development of novel therapies for refractory heart failure. He is now a Fellow of American College of Cardiology, American Heart Association, European Society of Cardiology and American College of Physicians.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"4",totalChapterViews:"0",totalEditedBooks:"1",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"989",title:"Pediatric Cardiology",slug:"pediatric-cardiology"}],chapters:[{id:"44513",title:"Ventricular Assist Devices: Expanding Role for Long Term Cardiac Support",doi:"10.5772/55822",slug:"ventricular-assist-devices-expanding-role-for-long-term-cardiac-support",totalDownloads:1933,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Rachit M. Shah, Megha Goyal, Suchi Shah, Sharath Kommu, Anit\nMankad and Rohit R. Arora",downloadPdfUrl:"/chapter/pdf-download/44513",previewPdfUrl:"/chapter/pdf-preview/44513",authors:[{id:"61874",title:"Dr.",name:"Rachit",surname:"Shah",slug:"rachit-shah",fullName:"Rachit Shah"},{id:"61881",title:"Dr.",name:"Rohit",surname:"Arora",slug:"rohit-arora",fullName:"Rohit Arora"},{id:"117031",title:"Dr.",name:"Sharath",surname:"Kommu",slug:"sharath-kommu",fullName:"Sharath Kommu"},{id:"158461",title:"Dr.",name:"Megha",surname:"Goyal",slug:"megha-goyal",fullName:"Megha Goyal"},{id:"158462",title:"Dr.",name:"Suchi",surname:"Shah",slug:"suchi-shah",fullName:"Suchi Shah"},{id:"166403",title:"Dr.",name:"Anit",surname:"Mankad",slug:"anit-mankad",fullName:"Anit Mankad"}],corrections:null},{id:"44522",title:"Echocardiography and Hemodynamic Monitoring Tools for Clinical Assessment of Patients on Mechanical Circulatory Support",doi:"10.5772/55918",slug:"echocardiography-and-hemodynamic-monitoring-tools-for-clinical-assessment-of-patients-on-mechanical-",totalDownloads:2098,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Sabino Scolletta, Bonizella Biagioli, Federico Franchi and Luigi\nMuzzi",downloadPdfUrl:"/chapter/pdf-download/44522",previewPdfUrl:"/chapter/pdf-preview/44522",authors:[{id:"54044",title:"Prof.",name:"Sabino",surname:"Scolletta",slug:"sabino-scolletta",fullName:"Sabino Scolletta"},{id:"166468",title:"Dr.",name:"Bonizella",surname:"Biagioli",slug:"bonizella-biagioli",fullName:"Bonizella Biagioli"},{id:"166469",title:"Dr.",name:"Federico",surname:"Franchi",slug:"federico-franchi",fullName:"Federico Franchi"},{id:"166471",title:"Dr.",name:"Luigi",surname:"Muzzi",slug:"luigi-muzzi",fullName:"Luigi Muzzi"}],corrections:null},{id:"43675",title:"Gastrointestinal Bleeding with Continuous Flow Left Ventricular Assist Devices (LVADs)",doi:"10.5772/56010",slug:"gastrointestinal-bleeding-with-continuous-flow-left-ventricular-assist-devices-lvads-",totalDownloads:2923,totalCrossrefCites:1,totalDimensionsCites:4,hasAltmetrics:0,abstract:null,signatures:"Geetha Bhat, Mukesh Gopalakrishnan and Ashim Aggarwal",downloadPdfUrl:"/chapter/pdf-download/43675",previewPdfUrl:"/chapter/pdf-preview/43675",authors:[{id:"157569",title:"Dr.",name:"Geetha",surname:"Bhat",slug:"geetha-bhat",fullName:"Geetha Bhat"},{id:"158327",title:"Dr.",name:"Ashim",surname:"Aggarwal",slug:"ashim-aggarwal",fullName:"Ashim Aggarwal"},{id:"165742",title:"Dr.",name:"Mukesh",surname:"Gopalakrishnan",slug:"mukesh-gopalakrishnan",fullName:"Mukesh Gopalakrishnan"}],corrections:null},{id:"44015",title:"Allosensitization and the Ventricular Assist Device: Dual Evolution of Technology",doi:"10.5772/56426",slug:"allosensitization-and-the-ventricular-assist-device-dual-evolution-of-technology",totalDownloads:1619,totalCrossrefCites:0,totalDimensionsCites:2,hasAltmetrics:0,abstract:null,signatures:"Myra Coppage",downloadPdfUrl:"/chapter/pdf-download/44015",previewPdfUrl:"/chapter/pdf-preview/44015",authors:[{id:"159534",title:"Dr.",name:"Myra",surname:"Coppage",slug:"myra-coppage",fullName:"Myra Coppage"}],corrections:null},{id:"43987",title:"Preliminary Trial of Lower Leg Thermal Therapy for Patients with Terminal Heart Failure Fitted with Left Ventricular Assist Device",doi:"10.5772/55819",slug:"preliminary-trial-of-lower-leg-thermal-therapy-for-patients-with-terminal-heart-failure-fitted-with-",totalDownloads:1558,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Kazuo Komamura, Toshiaki Shishido and Takeshi Nakatani",downloadPdfUrl:"/chapter/pdf-download/43987",previewPdfUrl:"/chapter/pdf-preview/43987",authors:[{id:"19651",title:"Dr.",name:"Kazuo",surname:"Komamura",slug:"kazuo-komamura",fullName:"Kazuo Komamura"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"5281",title:"Microcirculation Revisited",subtitle:"From Molecules to Clinical Practice",isOpenForSubmission:!1,hash:"7f470d69a6403e887b362de09d244f73",slug:"microcirculation-revisited-from-molecules-to-clinical-practice",bookSignature:"Helena Lenasi",coverURL:"https://cdn.intechopen.com/books/images_new/5281.jpg",editedByType:"Edited by",editors:[{id:"68746",title:"Dr.",name:"Helena",surname:"Lenasi",slug:"helena-lenasi",fullName:"Helena Lenasi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1092",title:"Atrial Septal Defect",subtitle:null,isOpenForSubmission:!1,hash:"e1361c07e99c214eeae3aee284b23f10",slug:"atrial-septal-defect",bookSignature:"P. Syamasundar Rao",coverURL:"https://cdn.intechopen.com/books/images_new/1092.jpg",editedByType:"Edited by",editors:[{id:"68531",title:"Dr.",name:"P. Syamasundar",surname:"Rao",slug:"p.-syamasundar-rao",fullName:"P. Syamasundar Rao"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5351",title:"Contemporary Challenges in Endocarditis",subtitle:null,isOpenForSubmission:!1,hash:"7e56ebec7c0e74f37026b3ed08826e75",slug:"contemporary-challenges-in-endocarditis",bookSignature:"Michael S. Firstenberg",coverURL:"https://cdn.intechopen.com/books/images_new/5351.jpg",editedByType:"Edited by",editors:[{id:"64343",title:"Dr.",name:"Michael S.",surname:"Firstenberg",slug:"michael-s.-firstenberg",fullName:"Michael S. Firstenberg"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"949",title:"Cardiac Transplantation",subtitle:null,isOpenForSubmission:!1,hash:"4c87dc890fdeaa9301005f3bf6331d8e",slug:"cardiac-transplantation",bookSignature:"Susan D. Moffatt-Bruce",coverURL:"https://cdn.intechopen.com/books/images_new/949.jpg",editedByType:"Edited by",editors:[{id:"63413",title:"Dr.",name:"Susan",surname:"Moffatt-Bruce",slug:"susan-moffatt-bruce",fullName:"Susan Moffatt-Bruce"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"683",title:"Endocarditis",subtitle:null,isOpenForSubmission:!1,hash:"8c3b925c21826510dd24c316c477f48c",slug:"endocarditis",bookSignature:"Francisco Ramón Breijo-Márquez",coverURL:"https://cdn.intechopen.com/books/images_new/683.jpg",editedByType:"Edited by",editors:[{id:"91997",title:"Prof.",name:"Francisco Ramón",surname:"Breijo-Márquez",slug:"francisco-ramon-breijo-marquez",fullName:"Francisco Ramón Breijo-Márquez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5434",title:"Aortic Aneurysm",subtitle:null,isOpenForSubmission:!1,hash:"1fe6fcf4165a7f7732d4eb9c6b7a90fd",slug:"aortic-aneurysm",bookSignature:"Kaan Kirali",coverURL:"https://cdn.intechopen.com/books/images_new/5434.jpg",editedByType:"Edited by",editors:[{id:"155565",title:"Prof.",name:"Kaan",surname:"Kırali",slug:"kaan-kirali",fullName:"Kaan Kırali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3288",title:"Aortic Aneurysm",subtitle:"Recent Advances",isOpenForSubmission:!1,hash:"5a7e7d4043fc85c06da3afd8bfc6680d",slug:"aortic-aneurysm-recent-advances",bookSignature:"Cornelia Amalinei",coverURL:"https://cdn.intechopen.com/books/images_new/3288.jpg",editedByType:"Edited by",editors:[{id:"155903",title:"Associate Prof.",name:"Cornelia",surname:"Amalinei",slug:"cornelia-amalinei",fullName:"Cornelia Amalinei"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"730",title:"Microangiopathy",subtitle:null,isOpenForSubmission:!1,hash:"602513c25c56197d5ada1c7f3c45ec11",slug:"microangiopathy",bookSignature:"Raimondo De Cristofaro",coverURL:"https://cdn.intechopen.com/books/images_new/730.jpg",editedByType:"Edited by",editors:[{id:"85361",title:"Prof.",name:"Raimondo",surname:"De Cristofaro",slug:"raimondo-de-cristofaro",fullName:"Raimondo De Cristofaro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"4761",title:"Thrombosis, Atherosclerosis and Atherothrombosis",subtitle:"New Insights and Experimental Protocols",isOpenForSubmission:!1,hash:"891dcb25e37a9aa7001894fa470fa432",slug:"thrombosis-atherosclerosis-and-atherothrombosis-new-insights-and-experimental-protocols",bookSignature:"Mojca Bozic-Mijovski",coverURL:"https://cdn.intechopen.com/books/images_new/4761.jpg",editedByType:"Edited by",editors:[{id:"72261",title:"Dr.",name:"Mojca",surname:"Božič-Mijovski",slug:"mojca-bozic-mijovski",fullName:"Mojca Božič-Mijovski"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1294",title:"Aortic Valve Stenosis",subtitle:"Current View on Diagnostics and Treatment",isOpenForSubmission:!1,hash:"62d2c0a3f8db5aa6fd7e10de989b855a",slug:"aortic-valve-stenosis-current-view-on-diagnostics-and-treatment",bookSignature:"Petr Santavy",coverURL:"https://cdn.intechopen.com/books/images_new/1294.jpg",editedByType:"Edited by",editors:[{id:"62733",title:"Dr.",name:"Petr",surname:"Santavy",slug:"petr-santavy",fullName:"Petr Santavy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],ofsBooks:[]},correction:{item:{id:"79356",slug:"corrigendum-to-many-core-algorithm-of-the-embedded-zerotree-wavelet-encoder",title:"Corrigendum to: Many-Core Algorithm of the Embedded Zerotree Wavelet Encoder",doi:null,correctionPDFUrl:"https://cdn.intechopen.com/pdfs/74512.pdf",downloadPdfUrl:"/chapter/pdf-download/74512",previewPdfUrl:"/chapter/pdf-preview/74512",totalDownloads:null,totalCrossrefCites:null,bibtexUrl:"/chapter/bibtex/74512",risUrl:"/chapter/ris/74512",chapter:{id:"70013",slug:"many-core-algorithm-of-the-embedded-zerotree-wavelet-encoder",signatures:"Jesús Antonio Alvarez-Cedillo, Teodoro Alvarez-Sanchez, Mario Aguilar-Fernandez and Jacobo Sandoval-Gutierrez",dateSubmitted:"May 18th 2019",dateReviewed:"August 22nd 2019",datePrePublished:"December 7th 2019",datePublished:"March 11th 2020",book:{id:"7623",title:"Coding Theory",subtitle:null,fullTitle:"Coding Theory",slug:"coding-theory",publishedDate:"March 11th 2020",bookSignature:"Sudhakar Radhakrishnan and Muhammad Sarfraz",coverURL:"https://cdn.intechopen.com/books/images_new/7623.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"26327",title:"Dr.",name:"Sudhakar",middleName:null,surname:"Radhakrishnan",slug:"sudhakar-radhakrishnan",fullName:"Sudhakar Radhakrishnan"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"118717",title:"Ph.D.",name:"Jesús Antonio",middleName:null,surname:"Álvarez-Cedillo",fullName:"Jesús Antonio Álvarez-Cedillo",slug:"jesus-antonio-alvarez-cedillo",email:"jaalvarez@ipn.mx",position:null,institution:{name:"Instituto Politécnico Nacional",institutionURL:null,country:{name:"Mexico"}}},{id:"305584",title:"Dr.",name:"Teodoro",middleName:null,surname:"Alvarez-Sanchez",fullName:"Teodoro Alvarez-Sanchez",slug:"teodoro-alvarez-sanchez",email:"talvares@citedi.mx",position:null,institution:{name:"Instituto Politécnico Nacional",institutionURL:null,country:{name:"Mexico"}}},{id:"305586",title:"Dr.",name:"Jacobo",middleName:null,surname:"Sandoval-Gutierrez",fullName:"Jacobo Sandoval-Gutierrez",slug:"jacobo-sandoval-gutierrez",email:"jacobosandoval@hotmail.com",position:null,institution:{name:"Universidad Autónoma Metropolitana",institutionURL:null,country:{name:"Mexico"}}},{id:"305587",title:"Dr.",name:"Mario",middleName:null,surname:"Aguilar-Fernandez",fullName:"Mario Aguilar-Fernandez",slug:"mario-aguilar-fernandez",email:"maguilarf@ipn.mx",position:null,institution:{name:"Instituto Politécnico Nacional",institutionURL:null,country:{name:"Mexico"}}}]}},chapter:{id:"70013",slug:"many-core-algorithm-of-the-embedded-zerotree-wavelet-encoder",signatures:"Jesús Antonio Alvarez-Cedillo, Teodoro Alvarez-Sanchez, Mario Aguilar-Fernandez and Jacobo Sandoval-Gutierrez",dateSubmitted:"May 18th 2019",dateReviewed:"August 22nd 2019",datePrePublished:"December 7th 2019",datePublished:"March 11th 2020",book:{id:"7623",title:"Coding Theory",subtitle:null,fullTitle:"Coding Theory",slug:"coding-theory",publishedDate:"March 11th 2020",bookSignature:"Sudhakar Radhakrishnan and Muhammad Sarfraz",coverURL:"https://cdn.intechopen.com/books/images_new/7623.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"26327",title:"Dr.",name:"Sudhakar",middleName:null,surname:"Radhakrishnan",slug:"sudhakar-radhakrishnan",fullName:"Sudhakar Radhakrishnan"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"118717",title:"Ph.D.",name:"Jesús Antonio",middleName:null,surname:"Álvarez-Cedillo",fullName:"Jesús Antonio Álvarez-Cedillo",slug:"jesus-antonio-alvarez-cedillo",email:"jaalvarez@ipn.mx",position:null,institution:{name:"Instituto Politécnico Nacional",institutionURL:null,country:{name:"Mexico"}}},{id:"305584",title:"Dr.",name:"Teodoro",middleName:null,surname:"Alvarez-Sanchez",fullName:"Teodoro Alvarez-Sanchez",slug:"teodoro-alvarez-sanchez",email:"talvares@citedi.mx",position:null,institution:{name:"Instituto Politécnico Nacional",institutionURL:null,country:{name:"Mexico"}}},{id:"305586",title:"Dr.",name:"Jacobo",middleName:null,surname:"Sandoval-Gutierrez",fullName:"Jacobo Sandoval-Gutierrez",slug:"jacobo-sandoval-gutierrez",email:"jacobosandoval@hotmail.com",position:null,institution:{name:"Universidad Autónoma Metropolitana",institutionURL:null,country:{name:"Mexico"}}},{id:"305587",title:"Dr.",name:"Mario",middleName:null,surname:"Aguilar-Fernandez",fullName:"Mario Aguilar-Fernandez",slug:"mario-aguilar-fernandez",email:"maguilarf@ipn.mx",position:null,institution:{name:"Instituto Politécnico Nacional",institutionURL:null,country:{name:"Mexico"}}}]},book:{id:"7623",title:"Coding Theory",subtitle:null,fullTitle:"Coding Theory",slug:"coding-theory",publishedDate:"March 11th 2020",bookSignature:"Sudhakar Radhakrishnan and Muhammad Sarfraz",coverURL:"https://cdn.intechopen.com/books/images_new/7623.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"26327",title:"Dr.",name:"Sudhakar",middleName:null,surname:"Radhakrishnan",slug:"sudhakar-radhakrishnan",fullName:"Sudhakar Radhakrishnan"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},ofsBook:{item:{type:"book",id:"11947",leadTitle:null,title:"Power Converter Technology - Recent Advances, Design and Applications",subtitle:null,reviewType:"peer-reviewed",abstract:"
\r\n\tNowadays, the use of power converter technology has expanded into a countless wide range of low, medium, and high power applications due to the capability to efficiently manage electrical energy. In this regard, the high penetration of modern microprocessors capable of implementing high-performance nonlinear digital controllers and the recent advances in the development of high-speed switching power electronic devices where on-state loss and consequently switching loss of power semiconductors are significantly decreased, have contributed to increased efficiency of the new power converters. As a result, the size of power converters becomes small and the power converters with less heat generation have little environmental stress. Certain power converter topologies have been recently proposed in the literature for a variety of emerging applications. According to the state of the art, these novel converter topologies have different design criteria as well as particularities associated with the digital control system.
\r\n\r\n\tThis book intends to provide the reader with a comprehensive overview of the current state-of-the-art and address recent breakthroughs over the whole range of power converter technology featuring a special emphasis on design, emerging applications, and control.
",isbn:"978-1-80356-912-3",printIsbn:"978-1-80356-911-6",pdfIsbn:"978-1-80356-913-0",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,isNomenclature:!1,hash:"1f5c85b127faa05e07e46c646dcb4540",bookSignature:"Dr. Raul Gregor",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11947.jpg",keywords:"Matrix Converters, Multilevel Converters, Multimodular Converters, New Electronic Devices for Power Converters, Mitigation of EMI Noise Emissions, Power Quality, Renewable Energy, Electric Drives, Model-Based Predictive Control, Sliding Mode Control, Fixed Switching Control Techniques, Power Converter Topologies",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 5th 2022",dateEndSecondStepPublish:"June 15th 2022",dateEndThirdStepPublish:"August 14th 2022",dateEndFourthStepPublish:"November 2nd 2022",dateEndFifthStepPublish:"January 1st 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"2 months",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"Dr. R. Gregor has authored or coauthored about 160 technical papers in the field of power electronics and control systems. He obtained the Best Paper Award from the IEEE Transactions on Industrial Electronics, Industrial Electronics Society, in 2010.",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"175676",title:"Dr.",name:"Raul",middleName:null,surname:"Gregor",slug:"raul-gregor",fullName:"Raul Gregor",profilePictureURL:"https://mts.intechopen.com/storage/users/175676/images/system/175676.jpg",biography:"Raul Gregor was born in Asunción, Paraguay, in 1979. He received his Engineer degree in electronic engineering from the Catholic University of Asunción, Paraguay, in 2005. He received his M.Sc. and Ph.D. degrees in electronics, signal processing, and communications from the Higher Technical School of Engineering (ETSI), University of Seville, Spain, in 2008 and 2010, respectively. Since March 2010, Dr. Gregor has been Head of the Laboratory of Power and Control Systems (LSPyC) of the Engineering Faculty of the National University of Asunción (FIUNA), Paraguay. He is currently the Head of the Department of Electronic and Mechatronics Engineering of FIUNA. Dr. R., Gregor has authored or coauthored about 160 technical papers in the field of power electronics and control systems. He obtained the Best Paper Award from the IEEE Transactions on Industrial Electronics, Industrial Electronics Society, in 2010 and the Best Paper Award from the IET Electric Power Applications, in 2012. His research interests include multiphase drives, advanced control of power converter topologies, power quality, renewable energies, modeling, simulation, optimization and control of power systems, smart metering and smart grids and predictive control.",institutionString:"Universidad Nacional de Asunción",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"Universidad Nacional de Asunción",institutionURL:null,country:{name:"Paraguay"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"11",title:"Engineering",slug:"engineering"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"444315",firstName:"Karla",lastName:"Skuliber",middleName:null,title:"Mrs.",imageUrl:"https://mts.intechopen.com/storage/users/444315/images/20013_n.jpg",email:"karla@intechopen.com",biography:"As an Author Service Manager, my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"10198",title:"Response Surface Methodology in Engineering Science",subtitle:null,isOpenForSubmission:!1,hash:"1942bec30d40572f519327ca7a6d7aae",slug:"response-surface-methodology-in-engineering-science",bookSignature:"Palanikumar Kayaroganam",coverURL:"https://cdn.intechopen.com/books/images_new/10198.jpg",editedByType:"Edited by",editors:[{id:"321730",title:"Prof.",name:"Palanikumar",surname:"Kayaroganam",slug:"palanikumar-kayaroganam",fullName:"Palanikumar Kayaroganam"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2270",title:"Fourier Transform",subtitle:"Materials Analysis",isOpenForSubmission:!1,hash:"5e094b066da527193e878e160b4772af",slug:"fourier-transform-materials-analysis",bookSignature:"Salih Mohammed Salih",coverURL:"https://cdn.intechopen.com/books/images_new/2270.jpg",editedByType:"Edited by",editors:[{id:"111691",title:"Dr.Ing.",name:"Salih",surname:"Salih",slug:"salih-salih",fullName:"Salih Salih"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"117",title:"Artificial Neural Networks",subtitle:"Methodological Advances and Biomedical Applications",isOpenForSubmission:!1,hash:null,slug:"artificial-neural-networks-methodological-advances-and-biomedical-applications",bookSignature:"Kenji Suzuki",coverURL:"https://cdn.intechopen.com/books/images_new/117.jpg",editedByType:"Edited by",editors:[{id:"3095",title:"Prof.",name:"Kenji",surname:"Suzuki",slug:"kenji-suzuki",fullName:"Kenji Suzuki"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3828",title:"Application of Nanotechnology in Drug Delivery",subtitle:null,isOpenForSubmission:!1,hash:"51a27e7adbfafcfedb6e9683f209cba4",slug:"application-of-nanotechnology-in-drug-delivery",bookSignature:"Ali Demir Sezer",coverURL:"https://cdn.intechopen.com/books/images_new/3828.jpg",editedByType:"Edited by",editors:[{id:"62389",title:"PhD.",name:"Ali Demir",surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"872",title:"Organic Pollutants Ten Years After the Stockholm Convention",subtitle:"Environmental and Analytical Update",isOpenForSubmission:!1,hash:"f01dc7077e1d23f3d8f5454985cafa0a",slug:"organic-pollutants-ten-years-after-the-stockholm-convention-environmental-and-analytical-update",bookSignature:"Tomasz Puzyn and Aleksandra Mostrag-Szlichtyng",coverURL:"https://cdn.intechopen.com/books/images_new/872.jpg",editedByType:"Edited by",editors:[{id:"84887",title:"Dr.",name:"Tomasz",surname:"Puzyn",slug:"tomasz-puzyn",fullName:"Tomasz Puzyn"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"59028",title:"Parent Training Interventions for Children and Adolescents with Aggressive Behavioral Problems",doi:"10.5772/intechopen.73541",slug:"parent-training-interventions-for-children-and-adolescents-with-aggressive-behavioral-problems",body:'Children who display early disruptive and aggressive behavior are also at greater risk for delinquency, mood and anxiety disorders, and substance use in the long term. Moreover, longitudinal studies indicated that children with conduct problems initiated in childhood are at heightened risk for exhibiting persistent criminal behavior into adulthood. The presence of neurological deficits, which lead to difficulties managing peer conflicts, regulating emotions, and controlling impulses, and families with longstanding history of antisocial behavior prevents these youth from making important life transitions serving to further entrench them into a criminal lifestyle [1].
As for many forms of childhood psychopathology, a number of factors are associated with the emergence of aggressive and disruptive behavior. A contextual social-cognitive model has been employed to summarize the empirically identified risk factors for conduct problems in children [2, 3]. A set of neurobiological, family, peer, and social risk factors appear to be involved in the etiology of aggressive behavior problems.
There are several prenatal factors that can have an effect on a child’s developing brain and result in later conduct problems, including in utero drug and tobacco exposure and severe maternal nutritional deficiencies [4, 5].
Furthermore, child temperaments characterized by a “lack of control” (e.g., short attention span, negativism, restlessness, and emotional lability [6]), high emotional reactivity levels, difficult temperaments in general, and fearful and highly active children [7] are associated with behavior problems. Besides, genetic effects on children’s development of conduct problems are primarily manifested in interaction with environmental risk factors, such as child maltreatment, marital problems, and parental substance abuse [8].
The contextual social-cognitive model also focuses on children’s sequential cognitive processing and on contextual parenting processes; it assumes that aggressive children have distortions in their social-cognitive appraisals and deficiencies in their social problem-solving skills and that their parents have deficiencies in their parenting behaviors.
Aggressive children have cognitive distortions and deficiencies at two stages: appraisal and problem solution. Firstly, children have difficulty encoding incoming social information and in accurately interpreting social events and others intentions. Aggressive children tend to approach social situations with a hostile attribution bias: they assume the intention of others’ behavior is provocative and hostile in nature [9]. Furthermore, aggressive children tend to generate maladaptive solutions for perceived problems and have nonnormative expectations for the likelihood of success of aggressive and nonaggressive solutions to their social problems. Specific deficiencies have been noted in the solutions aggressive children offer in social situations: they often generate aggressive strategies because they expect that aggressive behavior will lead to the desired outcome.
Conduct problems have been shown to be influenced by the social context around the child, and the manifestations of the conduct problems directly affect family members, peers, and other persons in the children’s social context [10].
A wide range of family contextual factors lead to elevated risk of child conduct problems. Conduct problems during childhood are usually associated with characteristic family features. Particularly, they have been linked to poverty [11]; parent criminality; parental psychopathology, such as substance use, paternal antisocial personality disorder, or maternal depression [11]; marital conflict [12]; single and teenage parenthood [13]; stressful life events [11]; as well as insecure attachment in infancy and in preschool age, particularly disorganized attachment and avoidant attachment [14, 15, 16]. These familial risk factors can exert an effect on parenting practices, which in turn can exert an effect on child behavior.
The presence of parental psychopathology influences how parents perceive their child behavior and their educational practices. For example, mothers who suffer from depression see their child behavior as more upsetting during the worst period of depression [17]. Higher levels of maternal depression also predict caregivers’ use of inconsistent discipline, and the use of inconsistent discipline predicts aggressive behavior in children [18]. Studies demonstrated that maternal psychopathology is associated to a change of the perception of child behavior that is interpreted as deliberate and malevolent, and this could lead to the greater use of harsh discipline, which aggravate children behavioral problems.
Disruptive and aggressive behavior problems are associated with peculiar parenting practices. Parenting practices that have been associated with conduct problems in childhood include, as described by Patterson [19], increasingly coercive cycles of harsh parenting and noncompliance exhibited by child, beginning in the preschool/toddler years, particularly for children who display challenging and difficult temperament styles. It is common in insensitive and nonresponsive parenting at age 1, with reliability and pacing of parental reactions not adequately meeting the child’s needs. Inconsistently, severe discipline, as well as confusing or vague commands and directions, also characterizes parenting practices. Distinct lack of parental warmth and involvement and absence of parental monitoring and supervision represent risk factors for aggressive problems especially as children mature into adolescence [20]. Besides, the associations between child conduct problems and parenting factors are bidirectional, as the behavior and temperament displayed by the child can also affect the behavior the parent adopts [21]. For example, Patterson’s coercion model suggests that both parent and child are active participants in their interactions [22], and the model proposes a four-step process of escape conditioning [23]. At first, the parent commands the child to perform a behavior or scolds the child for their misbehavior. Then, the child responds to the parent’s request with an aversive behavior. Step 3 is the stage where the negative parent-child interaction can occur: if the parent stops the request, the child has escaped from the parent’s request. Lastly, the child withdraws their aversive behavior almost immediately after the parent terminates their request, thus reinforcing the parent’s withdrawal of the request.
Several studies point out that affective quality of parenting affects the quality of development on a prosocial, moral, and educational level [24, 25].
In an interesting recent longitudinal study [26], the development of aggressive behavior at the age of 8 was predicted by the appearance of similar early manifestations during early childhood, and this relationship was clearly mediated by the ways in which the mother tried to modulate and handle this child’s behavior since its onset, at around 2 years of life. In the insecure dyads, the mother tended to assert her power and control through coercive educative methods in order to manage the child’s disruptive behavior. In the secure dyads, instead, in the face of similar dysregulated behavior of the child, the mother activated responsive behaviors, without the need to take control of them or to assert her power in a coercive way.
The ability to give rules, structures, and boundaries, linked to a good affective sensitivity and responsiveness (sensitive discipline), is the focal component of parenting: connected to each other, they contribute to the development of a harmonious self-organization of the child, interacting with his temperament and his basic resources. As confirmed by several studies [27, 28], the individual and environmental factors interact with each other, and the context in which the child grows can act as a detonator or as a protective factor against possible neurobiological vulnerabilities. A “difficult” temperament does not necessarily negatively affect the quality of development, but acts in interaction with the environment by increasing child’s permeability to the influences of his context [29].
The task of developmental clinic psychology, with the strict contribution of the research, is intervening to reduce these possible escalations, in the interaction between the neurobiological vulnerability of the child and the parent’s mental state, with appropriate programs of proven effectiveness.
Parent training programs, which represent one form of parental intervention, are based on the premise that parenting practices contribute to the genesis, progression, and maintenance of both externalizing and internalizing problems. Competencies related to the self-regulation of emotion, cognition, and goal-directed behavior are shaped through repeated transactions between children’s biological characteristics and the social contexts in which they develop [30], especially the parent-child relationship. It is thought that parenting practices control variables for child behavior patterns and may serve to potentiate the expression of biological vulnerabilities and in doing so enhance risk that is carried forward across the life span [31].
From a theoretical perspective, BPT descends from the social interactional model, which was proposed by Patterson and his colleagues to explain how parents can shape externalizing problems of their children and adolescents [32].
As highlighted by Kaminski and colleagues in a review [33], BPTs often share a range of common contents. They usually focus on child development knowledge and care, in order to give parents information about how to provide appropriate physical care and environment and information about typical child behavior and development. Another crucial component concerns the importance of positive and non-disciplinary interaction with children: parents are taught to use adequate strategies to promote positive parent-child interactions, such as demonstrating enthusiasm, following child’s interest, and providing appropriate attention. During BPTs, parents also learn how to respond sensitively to child’s emotional and psychological need and to provide developmentally appropriate physical contact and affection; emotional communication is an important component too: parents are trained to use communication skills (e.g., active listening), to help children identify and express emotions. Parent training interventions largely focus on disciplinary communication and behavior management: so, parents learn to give clear and developmentally appropriate directions, to set limits and rules, and to state behavioral expectations and consequences; they are also taught to use adequate discipline strategies, monitoring and supervision practices, specific reinforcement, and punishment techniques. Parents should be trained to teach children to share and cooperate, use good manners, and get along with parents, siblings, and adults. Finally, BPTs focus on promoting children’s cognitive and academic skills.
Behavioral parent trainings are usually group interventions. The group setting allowed parents not to feel alone, blamed, criticized, or judged; they feel accepted and supported, which enable them to reflect upon their parenting approaches and to be open to new parenting practices. The group offers behavioral strategies and provides a collaborative, supportive context within which parents can express themselves and change. The group process promotes the parents’ ability to reflect on their histories and on their particular parenting styles. It invited them to disclose their thoughts, feelings, and behaviors about parenting and examine those of their children as they discussed various aspects of their parenting and of their parent-child relationships [34].
Therapeutic alliance is crucial for successful parent training interventions, and group’s leader behavior plays a key role. Indeed, leader’s positive behaviors predicted change in parent’s positive behaviors toward children [35]. Specifically, leader praise and reflective behaviors are demonstrated as important categories because of their impact on the very same parent behaviors. The level of leader praise significantly predicts change in the parental use of praise: the more praise modeled by the leader to parents in the group, the more likely parents use praise with their children at home [36]. Especially when parents are sharing their experiences, the group leader should highlight and praise parents’ improvements, even if they are small, in order to create a supportive context and let parents be able to express themselves.
Behavioral parent training (BPT) has been studied with rigorous research designs and is recognized as the leading intervention strategy for disruptive and aggressive behaviors (for a review see [37]). Some of the most employed parent training interventions for aggressive behavior problems are presented below.
The Coping Power (CP) Program is a multicomponent treatment program, delivered in a group setting, and was developed using a contextual social-cognitive model as a conceptual framework for identifying intervention objectives [3]. The contextual social-cognitive model focuses on the contextual parenting practices and on children’s sequential cognitive processing in the development and rise of children’s behavioral problems. The CP Program includes a CP-child component, which consists in 36 group sessions and 16 parents’ sessions, both delivered over 12 months. Parents are met in groups of five families; typically, only one parent per family joins the groups. The child and his/her parent received the treatment on the same day.
Researches on risk factors within the contextual social-cognitive model have led to the development of specific modules within the CP Program, with a structured manual. The CP-child component focuses on children’s ability to pursue long-term and short-term goals and their academic and study abilities. Children learn to recognize the emotions and their physiological and cognitive features, mainly anger, and to manage anger arousal (using self-statements, distractions, and relaxation). Children also improve their perspective talking skills, attribution retraining, and social problem-solving skills. Finally, children are couched to use strategies in order to cope with peer pressure and make new friend, avoiding deviant peer groups.
The CP-parent component aims to increase positive parental attention and reward appropriate child behaviors. Parents learn to ignore minor disruptive behaviors, to give effective instructions, and to establish adequate rules and expectations for their children at home. Parents are also taught to use efficient consequences to negative child behaviors. The CP Program aims to empower family communication and reduce parental stress. Specifically, parents are taught principles of social learning theory and a description of how continuous exposure to negative social information maintains unhelpful emotion and negative behavior patterns. Instruction is provided as to cognitive approaches to track and alter dysfunctional thoughts that contribute to negative parenting patterns and to functional thoughts that may contribute to alternative positive parenting approaches to emotion regulation. Moreover, parents are instructed on skills to effectively ignore minor disruptive behavior, give effective instructions, and establish rules and expectations; they are instructed on approaches to punishment that facilitate appropriate social and emotional development. Information and rationale to devalue physical punishment are provided and discussed. Parents learn strategies to implement time-out, privilege removal, work chores, and “total reward shutdown” for negative child behavior. Finally, parents of children with aggressive/disruptive behavior experience high degrees of stress and disproportionate life challenges. The development of effective strategies to manage stress and cope with life challenges provide a “base” from which parenting strategies can be developed. In these sessions parents are taught strategies to regulate their emotions, ways to relax, and approaches to organize their time.
Numerous studies demonstrated the efficacy of the Coping Power Program in reducing disruptive and aggressive behaviors in children and that this reduction is maintained at follow-up evaluations [38, 39, 40].
The Incredible Years (IY; [41, 42]) includes three different but linked evidence-based programs: the parents, the teachers, and the children’s series. Their goal is the promotion of social and emotional skills, as well as the prevention and treatment of conduct problems.
The IY BASIC Parent Programs [43] are addressed for parents of children of different ages, from babies (6 weeks–1 year) to school-age (6–12 years). All these programs include age-appropriate examples of culturally diverse families and children with different temperamental features. The IY BASIC Parent Programs train parents in child-directed play skills, praise, and rewards, limit setting, and how to handle misbehavior. Parents are trained to increase the use of positive and consistent strategies in order to strengthen children’s prosocial behaviors and social skills. These programs are offered weekly for 9–20 sessions to groups of 8–12 parents; they emphasize developmentally age-appropriate parenting skills that help children accomplish key developmental milestones. The main goals of the programs include the promotion of parent skills and the empowerment of family’s relationship by increasing positive parenting, parent-child attachment, and confidence about nurturing; parents also learn to use child-directed play interactions to increase children’s social-emotional, academic, verbal, and persistence skills. The program proposes to reduce harsh and physically violent discipline and increase positive discipline strategies such as ignoring and redirecting, logical consequences, time-out, and problem-solving. The IY BASIC Parent Programs highlight the importance of increasing family assistance systems, as well as the empowerment of home-school alliance and parents’ participation in school-related activities.
Furthermore, there are two additional parenting programs addressed for specific populations [44]. The ADVANCE parenting program delivered after conclusion of the BASIC preschool or school-age programs was developed for particular high-risk and designated populations and focuses on parents’ interpersonal risk factors. The School Readiness Program for children aging 3–5 years is a brief prevention program designed to teach parent’s academic, social, and emotional coaching and strategies to help children develop preliteracy competencies.
The efficacy of the IY BASIC Parent Programs for children with aggressive behavior problems has been demonstrated in a large number of studies [45, 46]. Other studies [47] also indicated the additive benefits of the ADVANCE parenting program on children’s prosocial solution generation and parents’ marital interactions. Several studies have also shown that IY treatment effects are durable 1–3 years posttreatment [48].
Triple P (Positive Parenting Program) is a multilevel, preventively oriented, parenting, and family support strategy developed by Sanders and colleagues at the University of Queensland in Brisbane, Australia [49, 50]. The Triple P’s purpose is the prevention of behavioral, emotional, and developmental problems and child maltreatment by increasing family protective factors and reducing risk factors related with child abuse. The program aspires to enhance the knowledge, abilities, self-esteem, independency, coping skills, and resilience of caregivers and to encourage caring, positive, non-violent, and low-conflict environments for children and young people. The Triple P also promotes children’s social, emotional, language, intellectual, and behavioral skills through positive parenting practices. The program targets different developmental periods, from infancy, toddlerhood, and preschool age to preadolescence and adolescence.
The program also includes five levels of intervention. The first one is the Universal Triple P, a media-based parenting information campaign; the second level is the Selected Triple P which is addressed for parents with specific concerns about their children’s behavior or development. Primary Care Triple P is a narrow-focus parenting skills training for parents who require consultations or active skills training. The fourth level includes the Standard Triple P, Group Triple P, Self-Directed Triple P, which are broad-focus parenting skills training, and typically targets parents of children with more severe behavior problems. Finally, there is the Enhanced Triple P, a behavioral family intervention, specifically addressed for parents of children with concurrent child behavior problems and family dysfunction.
Five core positive parenting principles are used in Triple P to address specific risk and protective factors known to promote positive developmental and mental health outcomes in children and reduce child maltreatment: developing positive relationships, encouraging desirable behavior, teaching new skills, teaching new behaviors, and managing misbehavior.
Parent-Child Interaction Therapy (PCIT; [51]) is a brief and effective intervention for young children with conduct problems. PCIT is an empirically supported treatment [52] involving two distinct stages. Child-Directed Interaction (CDI), based on attachment theory, was designed to coach parents to establish tender and sympathetic interactions with their children, and Parent-Directed Interaction (PDI), based on social learning theory, was designed to teach parents to monitor and employ consequences to modify child’s negative behaviors. In PCIT, parents learn specific skills that foster a close, secure relationship with their child, as well as skills that facilitate constructive, consistent, and predictable limits and discipline.
In the first phase, CDI, parents are taught to use traditional play therapy skills while they play with their child, with the goals of strengthening the parent-child relationship, building the child’s self-esteem, and increasing the child’s prosocial behaviors. In the second phase, PDI, parents learn behavior modification principles and are guided in the use of specific techniques such as giving effective commands and using time-out.
The Connect Program [53] is a manualized attachment-focused program for parents of adolescents who engage in aggressive, violent, and antisocial behavior. Parents attended weekly 1 h group sessions for 10 weeks. Each session of the Connect Program begins with the introduction of an attachment principle that captures a key aspect of the parent-teen relationship and common parenting challenges. The main principles of the Connect Program are the following: (a) attachment is for life, (b) conflict is part of attachment, and (c) and understanding, growth, and change begin with empathy. The program intends to enhance recognition that attachment needs continue throughout life but are expressed differently as children develop; consequently, parents develop skills in reframing children’s behavior in terms of their developmental level and attachment needs. The Connect Program also intends to enhance recognition and acceptance of conflict as a normative part of relationships, particularly during adolescence, which often communicates attachment needs. Parents develop skills in regulating affect, maintaining connection, and negotiating in the face of conflict. Moreover, the Connect Program highlights the crucial role of empathy for children and parents, and parents learn skills in empathic listening with others in conflict situations.
In order to show the principle and build parenting skills and knowledge, the program uses role-playing and reflection exercises. Precisely, the Connect Program focuses on the empowerment of abilities related to the essential components of secure attachment: parental sensitivity, partnership and mutuality, parental reflective function, and dyadic affect regulation.
Two pilot studies of the Connect Program with parents of adolescents referred for serious antisocial and aggressive behavior revealed significant pre- to posttreatment reductions in youth’s internalizing and externalizing problems [54, 55].
Chronic liver disease is a major health problem worldwide. This situation is generated by a wide range of chronic liver injuries such as chronic viral hepatitis, chronic alcohol abuse, non-alcoholic fatty liver disease, autoimmune hepatitis, primary biliary cirrhosis, and other less frequent causes. Regardless of the liver disease etiology, a common pathway of fibrosis is set up, which progresses and leads to liver cirrhosis that may be complicated by portal hypertension, liver failure, and hepatocellular carcinoma.
The evaluation of patients with chronic liver disease must be as simple as possible, cost efficient, and easily repeatable. While the liver biopsy is still considered the gold standard for liver fibrosis evaluation, due to its shortcomings (invasiveness, potential complications, inter-/intra-observer variability, sampling error) [1, 2, 3] scientific and practical interest has focused on the development of noninvasive techniques for the diagnosis of liver fibrosis.
Elastography can be used to assess liver fibrosis noninvasively. It measures the tissue behavior when mechanical stress is applied, either using ultrasound (ultrasound-based elastography) or magnetic resonance (magnetic resonance elastography).
Ultrasound elastography is perhaps the most important breakthrough in the evolution of ultrasound in the last 20 years. The basic idea behind liver elastography is that the elasticity of the tissue examined offers information on liver health. A stiffer liver tissue usually indicates the presence of chronic liver disease.
Mainly, most liver ultrasound elastography techniques are based on the principle of measuring the speed of the shear wave that propagates through the liver which is influenced by the stiffness of the tissue. The speed of the shear wave is proportional to the tissue stiffness. Basically, the stiffer the liver, the faster the shear wave will propagate through the liver.
The value of ultrasound-based elastography for staging chronic liver disease has been established by numerous studies [4, 5, 6, 7]. Moreover, its value for evaluating and predicting chronic liver disease complications (portal hypertension, hepatocellular carcinoma) has been also proven in different studies [8, 9, 10].
The European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) and the World Federation of Societies for Ultrasound in Medicine and Biology (WFUMB) have issued guidelines and recommendations on the clinical use of ultrasound-based elastography and describe in detail their basic principles [11, 12, 13].
This chapter focuses on the basic principles of elastography, which is an important aspect for every clinician or practitioner who is performing or learning liver elastography. Moreover, clinical features such as the examination techniques of different liver elastography methods and the factors that influence the liver elastography results are described and discussed.
Elastography assesses tissue elasticity, which is the tendency of tissue to resist deformation with an applied force or to resume its original form after removal of the force. Elastography can be considered a type of remote palpation that allows the measurement and display of the biomechanical properties in a tissue that acts against the shear deformation. Shear deformation is generated by applying a force either to a single location or broadly across the body surface. A force can be applied by vibrating the body surface that produces a natural internal physiological motion or using the ultrasound transducer to create focused acoustic radiation force at controlled depths [13, 14].
All ultrasound-based elastography methods use ultrasound to measure the tissue shear deformations resulting from an applied force. The type of force applied can be quasi-static or dynamic. Quasi-static forces do not allow the acquiring of images that are quantitative for tissue properties. Dynamic forces allow the quantification of the tissue properties. They include impulses that can be produced mechanically at the body surface or by acoustic radiation force impulse at controlled depths.
According to the EFSUMB guidelines [11], elastography techniques can be classified according to how the displacement data are shown. Three options are available as follows:
Display of displacement without further processing. This type of displacement is used in acoustic radiation force impulse (ARFI) imaging, which allows a quantitative measurement (units of μm), and the image displayed is scaled between bright (soft tissue) and dark (hard tissue). This technique is not used for liver elastography measurements.
Display of tissue strain or strain rate, which is calculated from the spatial gradient of displacement or velocity. This type of displacement works according to Hooke’s law, which states that E = σ/ε, where stress is the applied force per unit area and strain is the change in length of the tissue divided by its original length. If the stress (not known in strain module) is assumed to be the same for all image locations, an image of strain can be thought of as an inverse relative to Young’s modulus map. Strain is a quantitative measurement (%) and image brightness is typically scaled between bright (soft) and dark (hard).
Display of shear wave speed, which is calculated by measuring the arrival time of a shear wave at different locations in the tissue. This is possible only when the force is applied dynamically. Shear wave speed may be displayed in units of m/s. Alternatively, it may be converted to either Young’s modulus E or shear modulus G, which are expressed in units of kilopascal (kPa). These elastography techniques are called shear wave elastography (SWE) and include transient elastography (TE), point shear wave elastography (pSWE), and multidimensional shear wave elastography (2D-SWE and 3D-SWE).
For liver applications, elastography methods that display the shear wave speed are the most commonly used in practice, followed by strain and displacement imaging (for liver lesions), which are less frequently used. The elastography methods integrated into clinical practice for the liver are described in Table 1.
Strain/displacement techniques | Strain elastography |
---|---|
Shear wave elastography techniques | Transient elastography Point shear wave elastography Multidimensional shear wave elastography (2D-SWE and 3D-SWE) |
Elastography methods used for the liver.
Strain elastography is the most widely implemented elastography method on commercial systems; however, it is the least used technique for liver applications. The force used in strain elastography is either produced with the ultrasound probe or due to the internal physiological motion. The axial displacement images are calculated using radiofrequency echo correlation tracking or Doppler processing, which converts the axial displacement images into strain images [14, 15]. Excitation with manual pressure measures elasticity in superficial tissues. A disadvantage of this excitation method is that manual stress is not efficiently transmitted to deeper tissues. Excitation from natural physiologic motion, such as cardiac pulsation and respiration, is another mechanism of generating tissue stress. Deep organs, such as the liver or the kidney, can be assessed with this method [14, 15].
Strain elastography is a semi-quantitative method for tissue elastic property analysis, which has not demonstrated high accuracy for liver applications.
TE has been designed only for liver elasticity measurement. It uses an automated piston, which is also a disk-shaped ultrasound transducer, that applies a low-frequency (50 Hz) mechanical push to the body surface with controlled applied force [16]. A transient shear wave is created that propagates into the tissue. The shear wave propagation velocity is proportional to tissue stiffness, which increases with fibrosis [17]. TE measures tissue stiffness over a 1 cm diameter and 4 cm length region of tissue, which is 100 times larger than those evaluated with liver biopsy. The transient shear wave deformation is propagated at a constant speed, for 4 cm, and measured by a straight line automatically displayed in a displacement M-mode shown in the result (Figure 1) [11]. If the pulse is not transmitted and recorded successfully, the software does not provide a reading. Transient elastography is marketed under the trade name FibroScan®. Stiffness values are presented in kPa. Controlled attenuation parameter (CAP) is a technology that quantifies liver steatosis by measuring the energy loss as the sound wave passes through the medium. Total attenuation at 3.5 MHz is expressed in dB/m, and steatosis is estimated using the same radiofrequency data as elastography, in the same location that stiffness is measured [18]. A schematic representation of the basic principle of TE is presented in Figure 2.
Transient elastography (TE) and controlled attenuation parameter (CAP) with the Fibroscan® device. Sample display showing the echo M-scan on the left, single-line amplitude A-scan in the middle, and the displacement M-mode after a vibration-controlled impulse push on the surface on the right. Numeric values for CAP are displayed on the left side (db/m) and for TE on the right side (kPa).
Schematic representation of the principle of transient elastography. A mechanically induced impulse at the tissue surface with an A-mode transducer produces an axial shear wave pulse. The measured shear wave speed is proportional to the fibrosis.
Applying an ARFI at a controlled depth within a tissue generates a shear wave that propagates away from the pushing beam’s axis and focal point (Figure 3). Its average speed of propagation from the focal point positioned on one lateral boundary of a measurement region of interest (ROI) to another on the opposite lateral boundary of the ROI may be measured by detecting its time of arrival at that point, relative to that of the ARFI [14]. Ultrasound imaging is used to guide placement of the ROI; however, no elasticity images are produced (Figure 4). First introduced by Siemens, pSWE is available on different commercial systems from different vendors (e.g., Philips, Samsung, Hitachi, Esaote). The results can be expressed either in m/s or in kPa.
Schematic representation of the principle of point shear wave elastography (pSWE). An ultrasound-induced focused radiation force impulse is produced at a controlled depth generating a lateral shear wave in a region of interest (ROI). The measured shear wave speed represents tissue stiffness.
Point shear wave elastography (pSWE) implemented on virtual touch quantification (VTQ) from Siemens (4a), ElastPQ from Philips (4b), and S-Shearwave from Samsung (4c). A region of interest (ROI) is placed 1–2 cm below the liver capsule for liver stiffness assessment.
In this technique, acoustic radiation force impulse is used to create tissue displacement at multiple points (Figure 5). By placing the ARFI focus at multiple sequential locations and, at each, detecting the shear wave speed and arrival time, quantitative images of the shear wave speed can be produced [13, 14]. A large quantitative color-coded elasticity map (elastogram) is presented, which can be overlaid on the B-mode image or displayed separately, side by side (Figure 6). In addition to the visual impression of the elastogram against a color scale, a quantitative measurement can be obtained by placing smaller ROIs (measurement boxes) inside the elastogram. The result of one measurement is displayed usually as the mean and standard deviation either in m/s as shear wave propagation speed or in Young’s modulus in kPa (Figure 6).
Schematic representation of the principle of 2D shear wave elastography (2D-SWE). Multiple ultrasound-induced ARFI lines create transverse shear waves that produce quantitative images of their speed.
2D shear wave elastography (2D-SWE) implemented by SuperSonic imagine (6a) and General Electric (6b). The elastogram, which is superimposed on the B-mode image, is placed 1–2 cm below the liver capsule. A circular ROI is placed inside the elastogram for tissue stiffness measurements. A color-coded scaled quality map (6b left image) can be available for guiding the measurement placement. The result is expressed in kPa and m/s.
This technique is available on multiple ultrasound systems including SuperSonic Imagine, GE Healthcare, Canon, Philips, Siemens, Mindray.
All elastography methods follow an evaluation technique that enables a good approach toward the liver parenchyma. The patients will be positioned in a supine position with their right arm in maximal abduction in order to widen the intercostal spaces thus offering a better view of the right liver lobe. The measurements from the left liver lobe are not recommended due to higher values and significant variability. A minimum training is required that one may perform liver stiffness measurements, and the acquisition itself will take usually less than 5 minutes. Patients should be in fasting condition (for at least 3 hours) and rest for a minimum of 10 minutes prior to the evaluation. When scanning for the ultrasound section, large vessels and artifacts should be avoided in both A-mode (TE) and B-mode image (pSWE and 2D-SWE) as well as deep inspiratory movements [12, 19, 20]. A dedicated ultrasound gel is used as an interface between the probe and the patient’s skin.
For the TE technique, the transducer is placed between the 9th and 11th right intercostal spaces in order to penetrate at least 4 cm thickness of liver parenchyma. The device offers an A-mode image that will assist the examiner to choose the best section into the liver. TE probe will transmit a mechanical impulse to the liver through a special piston (cylinder-shaped) that will apply a controlled force and thus will generate an elastic share wave. The probe is able to detect the velocity of the shear wave propagation into the liver reflecting the liver stiffness. Measurements are expressed in kilopascals with a range between 1.5 and 75 kPa. If the system detects errors in the acquisition process, it will automatically discard the measurement. At the end of the examination, the median of 10 measurements is displayed as well with the quality parameters (IQR, SR) [12, 19, 20]. For more accurate evaluations, manufacturers provided M, XL, and S probes that are recommended in order to overcome the confounding factor of obesity and thoracic circumference variations [20]. Studies demonstrated that at least 100 measurements are needed for training for one to achieve reliable results and 500 for expert level [21, 22]. It is also a reproducible method with an excellent intra- and interobserver agreement [23].
pSWE is a different method integrated into an ultrasound machine that evaluates liver fibrosis by noninvasive means. The acoustic “push” of the probe will generate share waves that will be transferred to liver parenchyma. Being an ultrasound-assisted method, ultrasound experience plays an important role in performing reliably the technique; even so, the reproducibility of the method is excellent [20, 24]. Using this technique, ascites is not a barrier for liver stiffness measurement. The probe, as in TE, should be placed in the right intercostal spaces in order to depict full liver tissue, without large vessels or other structures. Following, ROI should be set at depths between 1 and 6 cm beneath the liver capsule, ideally at 1–2 cm or 2–3 cm [25]. Special attention should be given to breathing oscillations and to cardiac cycles, patients should hold their breath for a few seconds during the acquisition, and the operator should choose a fair distance from the heart when selecting the ultrasound section and the ROI. However, no elastogram is provided by pSWE. Ten valid measurements are recommended and the result (the median of the measurements) is shown in m/s or kPa. Quality parameters such as IQR/M and standard deviation (SD) are used to optimize the performance of the method [11, 26].
As in the other methods, 2D-SWE uses a section through the right live lobe free of large vessels and other structures that need a steady image in order to make the acquisition. Patients should hold their breath for 4 to 5 seconds or even longer so that the high frame rate should record the tissue displacement of the share wave propagation into the color-coded box. Tissue displacement by the share waves is displayed by a color-coded map; thus, the technique offers both quantitative and qualitative assessments of the tissue stiffness. The colored box should be positioned at least 1–2 cm below the liver capsule but not deeper than 7 cm into the liver parenchyma [27]. The ROI will express the results as the mean value and standard deviation in kPa or in m/s. The biggest advantage that this method is offering is the fact that it evaluates a larger area of the liver parenchyma (up to 10 cm2). Usually, stiffer tissue will be depicted in red and softer tissue in blue. The operator should obtain as many elastogram loops to which in post-processing will select the ROI for LSM acquisition on the most homogeneous elastogram [26]. A minimum ultrasound training (>300) is necessary to be able to achieve good elastograms [28]. Recommended quality criteria are the IQR/M and measurement depth < 5.6 cm as quality technical [11, 29]. The median of at least three measurements should be used when performing LSM, but the examiner can choose between 3 and 15 measurements [30, 31, 32]. Even though it is a reproducible method [33], the inter- and intra-observer agreement in patients might be slightly inferior to pSWE [34, 35].
SE, offered by the Hitachi system (HI-RTE) [36], uses a regular ultrasound transducer that has embedded the SE module in it. It needs a good echoic window for the SE system to work properly; thus, a good ultrasound section is mandatory. The probe will generate echo signals under mild tissue compression and by this will produce a real-time elasticity image by overlapping a colored map on the B-mode image [37, 38]. It has all the advantages of the B-mode imaging and the examination approach will be as for the rest of the techniques with the patient in dorsal decubitus with the right arm in maximal abduction and a short breath hold when the acquisition is made, ascites and high BMI not being a contraindication for this method. However, the method is mainly used as a qualitative evaluation. Results will be displayed as blue for stiffer tissue and in red for soft tissue. Several methods have been developed in order to quantitatively assess tissue stiffness such as Elastic Ratio, Elastic Index, Elasticity Score, and Liver Fibrosis Index but without a proven consistency. The examiner must have ultrasound skills and special training is necessary for ROI setting and probe adjustment for homogeneous compression/relaxation index [20, 38]. Even though experience plays a role in SE, studies [39, 40] demonstrated that SE has a good and very good intra- and inter-observer variability and is a reproducible method.
When measuring liver stiffness with ultrasound-based elastography, we have to acknowledge some factors that can influence the results. Some of the factors are related to a physiological state, and some are linked to pathology. Hepatic inflammation with a threshold of ASAT and/or ALAT >5 times the normal value, hepatic congestion, cholestasis, acute hepatitis, and infiltrative liver disease are known to increase liver stiffness [20]. It is also known that food intake and physical activity can falsely increase LSM; thus, a minimum of 2 hours fasting and resting for 10 minutes before the examination are recommended [20, 41, 42]. Confounding factors of the SWE according to their method are depicted in Figure 7.
Associated confounding factors in ultrasound-based liver elastography.
Besides BMI, TE results can be influenced by increased transaminase, cholestasis, hepatic congestion, infiltrative liver disease, food intake, and heavy alcohol consumption. Several limitations of TE that are worth mentioning are the contraindication of LSM in patients with ascites and the lack of B-mode imaging [26, 46].
Ultrasound-based liver elastography confounding factors are described in Figure 7.
Ultrasound elastography comprises a set of techniques that noninvasively measure tissue stiffness. In this chapter, we have provided a brief introduction into the physical concepts of liver elastography and discussed several aspects important for clinical practice. In conclusion, elastography techniques that measure the shear wave speed are the most appropriate for liver applications. The liver elastography examination technique is standardized and co-founding factors need to be taken into consideration before performing liver stiffness measurements.
IntechOpen’s team of Scientific Advisors supports the publishing team by providing editorial and academic input and ensuring the highest quality output of free peer-reviewed articles. The Boards consist of independent external collaborators who assist us on a voluntary basis. Their input includes advising on new topics within their field, proposing potential expert collaborators and reviewing book publishing proposals if required. Board members are experts who cover major STEM and HSS fields. All are trusted IntechOpen collaborators and Academic Editors, ensuring that the needs of the scientific community are met.
",metaTitle:"STM Publishing and Free Peer Reviewed Articles | IntechOpen",metaDescription:"IntechOpen’s scientific advisors support the STM publishing team by offering their editorial input, ensuring a consistent output of free peer reviewed articles.",metaKeywords:null,canonicalURL:"scientific-advisors",contentRaw:'[{"type":"htmlEditorComponent","content":"\\n"}]'},components:[{type:"htmlEditorComponent",content:'
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. In the Engineering side, Digital Signal Processing, Computer Architecture, Electronics Devices, Digital Filtering and Engineering Management.\nApart from his Academic Interest and activities he loves sport especially, Cricket, Football, Snooker and Squash. He plays cricket for Esbjerg city in the second division team as an opener wicket keeper batsman. He is a very good player of squash but has not played squash since his arrival in Denmark.",institutionString:null,institution:null},{id:"611",title:"Prof.",name:"T",middleName:null,surname:"Nagarajan",slug:"t-nagarajan",fullName:"T Nagarajan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universiti Teknologi Petronas",country:{name:"Malaysia"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:13404},{group:"region",caption:"Middle and South America",value:2,count:11681},{group:"region",caption:"Africa",value:3,count:4213},{group:"region",caption:"Asia",value:4,count:22421},{group:"region",caption:"Australia and Oceania",value:5,count:2020},{group:"region",caption:"Europe",value:6,count:33697}],offset:12,limit:12,total:135704},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{topicId:"14"},books:[{type:"book",id:"11124",title:"Next-Generation Textiles",subtitle:null,isOpenForSubmission:!0,hash:"093f9e26bb829b8d414d13626aea1086",slug:null,bookSignature:"Dr. Hassan Ibrahim",coverURL:"https://cdn.intechopen.com/books/images_new/11124.jpg",editedByType:null,editors:[{id:"90645",title:"Dr.",name:"Hassan",surname:"Ibrahim",slug:"hassan-ibrahim",fullName:"Hassan Ibrahim"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11467",title:"Bismuth-Based Nanostructured Materials",subtitle:null,isOpenForSubmission:!0,hash:"951c872d9d90e13cfe7d97c0af91845e",slug:null,bookSignature:"Dr. William Wilson Anku",coverURL:"https://cdn.intechopen.com/books/images_new/11467.jpg",editedByType:null,editors:[{id:"196465",title:"Dr.",name:"William Wilson",surname:"Anku",slug:"william-wilson-anku",fullName:"William Wilson Anku"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11758",title:"Glass-Ceramics - Recent Advances, New Perspectives and Applications",subtitle:null,isOpenForSubmission:!0,hash:"e03ff7760e0aaea457f259ab63153846",slug:null,bookSignature:" Uday M. Basheer",coverURL:"https://cdn.intechopen.com/books/images_new/11758.jpg",editedByType:null,editors:[{id:"182041",title:null,name:"Uday",surname:"Basheer",slug:"uday-basheer",fullName:"Uday Basheer"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11761",title:"New Advances in Powder Technology",subtitle:null,isOpenForSubmission:!0,hash:"bd8063ae11e4fdd8626f5a095012c628",slug:null,bookSignature:"Dr. Shashanka Rajendrachari and Dr. Baris Avar",coverURL:"https://cdn.intechopen.com/books/images_new/11761.jpg",editedByType:null,editors:[{id:"246025",title:"Dr.",name:"Shashanka",surname:"Rajendrachari",slug:"shashanka-rajendrachari",fullName:"Shashanka Rajendrachari"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11764",title:"Electrodeposition - Modern Methods and Recent Advances",subtitle:null,isOpenForSubmission:!0,hash:"dd7b08197c3dcfef54b5e636795a67f7",slug:null,bookSignature:"Prof. Keith J. Stine",coverURL:"https://cdn.intechopen.com/books/images_new/11764.jpg",editedByType:null,editors:[{id:"192643",title:"Prof.",name:"Keith J.",surname:"Stine",slug:"keith-j.-stine",fullName:"Keith J. Stine"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11765",title:"Pyrometallurgy - New Perspectives",subtitle:null,isOpenForSubmission:!0,hash:"b0ed96047d5aadd003e16ab2884bb2f6",slug:null,bookSignature:"Dr. Swamini Chopra",coverURL:"https://cdn.intechopen.com/books/images_new/11765.jpg",editedByType:null,editors:[{id:"325912",title:"Dr.",name:"Swamini",surname:"Chopra",slug:"swamini-chopra",fullName:"Swamini Chopra"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11766",title:"Cast Iron - Production, Properties, Characterization, and Casting Defects Analysis",subtitle:null,isOpenForSubmission:!0,hash:"821766a37d38da743321864be6b2334a",slug:null,bookSignature:"Prof. Thoguluva Raghavan Vijayaram",coverURL:"https://cdn.intechopen.com/books/images_new/11766.jpg",editedByType:null,editors:[{id:"139338",title:"Prof.",name:"Thoguluva",surname:"Vijayaram",slug:"thoguluva-vijayaram",fullName:"Thoguluva Vijayaram"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11768",title:"Superplastic Materials - Fundamentals and Applications",subtitle:null,isOpenForSubmission:!0,hash:"16f7495ac63d4d02d103acc8485d9e4e",slug:null,bookSignature:"Dr. Jibran Khaliq",coverURL:"https://cdn.intechopen.com/books/images_new/11768.jpg",editedByType:null,editors:[{id:"458264",title:"Dr.",name:"Jibran",surname:"Khaliq",slug:"jibran-khaliq",fullName:"Jibran Khaliq"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11817",title:"Next Generation Fiber-Reinforced Composites - New Insights",subtitle:null,isOpenForSubmission:!0,hash:"bdff63f3c5e98fc95d76217516cb1420",slug:null,bookSignature:"Dr. Longbiao Li",coverURL:"https://cdn.intechopen.com/books/images_new/11817.jpg",editedByType:null,editors:[{id:"302409",title:"Dr.",name:"Longbiao",surname:"Li",slug:"longbiao-li",fullName:"Longbiao Li"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11819",title:"Adhesives - Science, Technology, Recent Advances, and Applications",subtitle:null,isOpenForSubmission:!0,hash:"c58b7d4c17e2a202af1dc4b906b7becb",slug:null,bookSignature:"Prof. António Bastos Pereira and Dr. Alexandre Luiz Pereira",coverURL:"https://cdn.intechopen.com/books/images_new/11819.jpg",editedByType:null,editors:[{id:"211131",title:"Prof.",name:"António",surname:"Pereira",slug:"antonio-pereira",fullName:"António Pereira"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11826",title:"Trends in the Development of Flame Retardants",subtitle:null,isOpenForSubmission:!0,hash:"a26eddafa7c826ce88dec81b1088f533",slug:null,bookSignature:"Dr. Fahmina Zafar, Prof. Nahid Nishat and Dr. Anujit Ghosal",coverURL:"https://cdn.intechopen.com/books/images_new/11826.jpg",editedByType:null,editors:[{id:"89672",title:"Dr.",name:"Fahmina",surname:"Zafar",slug:"fahmina-zafar",fullName:"Fahmina Zafar"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11829",title:"Advanced Rheology and Its Applications",subtitle:null,isOpenForSubmission:!0,hash:"095d5991269fb83f32687922efdc9fa9",slug:null,bookSignature:"Dr. Ashim Kumar Dutta",coverURL:"https://cdn.intechopen.com/books/images_new/11829.jpg",editedByType:null,editors:[{id:"277477",title:"Dr.",name:"Ashim",surname:"Dutta",slug:"ashim-dutta",fullName:"Ashim Dutta"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:22},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:6},{group:"topic",caption:"Business, Management and Economics",value:7,count:4},{group:"topic",caption:"Chemistry",value:8,count:15},{group:"topic",caption:"Computer and Information Science",value:9,count:18},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:8},{group:"topic",caption:"Engineering",value:11,count:37},{group:"topic",caption:"Environmental Sciences",value:12,count:5},{group:"topic",caption:"Immunology and Microbiology",value:13,count:8},{group:"topic",caption:"Materials Science",value:14,count:15},{group:"topic",caption:"Mathematics",value:15,count:8},{group:"topic",caption:"Medicine",value:16,count:61},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:2},{group:"topic",caption:"Neuroscience",value:18,count:2},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:7},{group:"topic",caption:"Physics",value:20,count:5},{group:"topic",caption:"Psychology",value:21,count:5},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:8},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:2}],offset:12,limit:12,total:22},popularBooks:{featuredBooks:[{type:"book",id:"7827",title:"Interpersonal Relationships",subtitle:null,isOpenForSubmission:!1,hash:"ebf41f4d17c75010eb3294cc8cac3d47",slug:"interpersonal-relationships",bookSignature:"Martha Peaslee Levine",coverURL:"https://cdn.intechopen.com/books/images_new/7827.jpg",editors:[{id:"186919",title:"Dr.",name:"Martha",middleName:null,surname:"Peaslee Levine",slug:"martha-peaslee-levine",fullName:"Martha Peaslee Levine"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10796",title:"Extracellular Vesicles",subtitle:"Role in Diseases, Pathogenesis and Therapy",isOpenForSubmission:!1,hash:"eb5407fcf93baff7bca3fae5640153a2",slug:"extracellular-vesicles-role-in-diseases-pathogenesis-and-therapy",bookSignature:"Manash K. Paul",coverURL:"https://cdn.intechopen.com/books/images_new/10796.jpg",editors:[{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10908",title:"Advances in Decision Making",subtitle:null,isOpenForSubmission:!1,hash:"126486f7f91e18e2e3539a32c38be7b1",slug:"advances-in-decision-making",bookSignature:"Fausto Pedro García Márquez",coverURL:"https://cdn.intechopen.com/books/images_new/10908.jpg",editors:[{id:"22844",title:"Prof.",name:"Fausto Pedro",middleName:null,surname:"García Márquez",slug:"fausto-pedro-garcia-marquez",fullName:"Fausto Pedro García Márquez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"95",title:"Applications and Experiences of Quality Control",subtitle:null,isOpenForSubmission:!1,hash:"4bcb22b1eee68210a977a97d5a0f363a",slug:"applications-and-experiences-of-quality-control",bookSignature:"Ognyan Ivanov",coverURL:"https://cdn.intechopen.com/books/images_new/95.jpg",editors:[{id:"22230",title:"Prof.",name:"Ognyan",middleName:null,surname:"Ivanov",slug:"ognyan-ivanov",fullName:"Ognyan Ivanov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"2160",title:"MATLAB",subtitle:"A Fundamental Tool for Scientific Computing and Engineering Applications - Volume 1",isOpenForSubmission:!1,hash:"dd9c658341fbd264ed4f8d9e6aa8ca29",slug:"matlab-a-fundamental-tool-for-scientific-computing-and-engineering-applications-volume-1",bookSignature:"Vasilios N. Katsikis",coverURL:"https://cdn.intechopen.com/books/images_new/2160.jpg",editors:[{id:"12289",title:"Prof.",name:"Vasilios",middleName:"N.",surname:"Katsikis",slug:"vasilios-katsikis",fullName:"Vasilios Katsikis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3560",title:"Advances in Landscape Architecture",subtitle:null,isOpenForSubmission:!1,hash:"a20614517ec5f7e91188fe8e42832138",slug:"advances-in-landscape-architecture",bookSignature:"Murat Özyavuz",coverURL:"https://cdn.intechopen.com/books/images_new/3560.jpg",editors:[{id:"93073",title:"Dr.",name:"Murat",middleName:null,surname:"Ozyavuz",slug:"murat-ozyavuz",fullName:"Murat Ozyavuz"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10739",title:"Global Decline of Insects",subtitle:null,isOpenForSubmission:!1,hash:"543783652b9092962a8fa4bed38eeb17",slug:"global-decline-of-insects",bookSignature:"Hamadttu Abdel Farag El-Shafie",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg",editors:[{id:"192142",title:"Dr.",name:"Hamadttu",middleName:null,surname:"Abdel Farag El-Shafie",slug:"hamadttu-abdel-farag-el-shafie",fullName:"Hamadttu Abdel Farag El-Shafie"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10911",title:"Higher Education",subtitle:"New Approaches to Accreditation, Digitalization, and Globalization in the Age of Covid",isOpenForSubmission:!1,hash:"223a02337498e535e967174c1f648fbc",slug:"higher-education-new-approaches-to-accreditation-digitalization-and-globalization-in-the-age-of-covid",bookSignature:"Lee Waller and Sharon Waller",coverURL:"https://cdn.intechopen.com/books/images_new/10911.jpg",editors:[{id:"263301",title:"Dr.",name:"Lee",middleName:null,surname:"Waller",slug:"lee-waller",fullName:"Lee Waller"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3568",title:"Recent Advances in Plant in vitro Culture",subtitle:null,isOpenForSubmission:!1,hash:"830bbb601742c85a3fb0eeafe1454c43",slug:"recent-advances-in-plant-in-vitro-culture",bookSignature:"Annarita Leva and Laura M. R. Rinaldi",coverURL:"https://cdn.intechopen.com/books/images_new/3568.jpg",editors:[{id:"142145",title:"Dr.",name:"Annarita",middleName:null,surname:"Leva",slug:"annarita-leva",fullName:"Annarita Leva"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3737",title:"MATLAB",subtitle:"Modelling, Programming and Simulations",isOpenForSubmission:!1,hash:null,slug:"matlab-modelling-programming-and-simulations",bookSignature:"Emilson Pereira Leite",coverURL:"https://cdn.intechopen.com/books/images_new/3737.jpg",editors:[{id:"12051",title:"Prof.",name:"Emilson",middleName:null,surname:"Pereira Leite",slug:"emilson-pereira-leite",fullName:"Emilson Pereira Leite"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"1770",title:"Gel Electrophoresis",subtitle:"Principles and Basics",isOpenForSubmission:!1,hash:"279701f6c802cf02deef45103e0611ff",slug:"gel-electrophoresis-principles-and-basics",bookSignature:"Sameh Magdeldin",coverURL:"https://cdn.intechopen.com/books/images_new/1770.jpg",editors:[{id:"123648",title:"Dr.",name:"Sameh",middleName:null,surname:"Magdeldin",slug:"sameh-magdeldin",fullName:"Sameh Magdeldin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4802},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"7827",title:"Interpersonal Relationships",subtitle:null,isOpenForSubmission:!1,hash:"ebf41f4d17c75010eb3294cc8cac3d47",slug:"interpersonal-relationships",bookSignature:"Martha Peaslee Levine",coverURL:"https://cdn.intechopen.com/books/images_new/7827.jpg",publishedDate:"July 27th 2022",numberOfDownloads:7175,editors:[{id:"186919",title:"Dr.",name:"Martha",middleName:null,surname:"Peaslee Levine",slug:"martha-peaslee-levine",fullName:"Martha Peaslee Levine"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",publishedDate:"July 27th 2022",numberOfDownloads:1981,editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10796",title:"Extracellular Vesicles",subtitle:"Role in Diseases, Pathogenesis and Therapy",isOpenForSubmission:!1,hash:"eb5407fcf93baff7bca3fae5640153a2",slug:"extracellular-vesicles-role-in-diseases-pathogenesis-and-therapy",bookSignature:"Manash K. Paul",coverURL:"https://cdn.intechopen.com/books/images_new/10796.jpg",publishedDate:"July 20th 2022",numberOfDownloads:2308,editors:[{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10908",title:"Advances in Decision Making",subtitle:null,isOpenForSubmission:!1,hash:"126486f7f91e18e2e3539a32c38be7b1",slug:"advances-in-decision-making",bookSignature:"Fausto Pedro García Márquez",coverURL:"https://cdn.intechopen.com/books/images_new/10908.jpg",publishedDate:"July 27th 2022",numberOfDownloads:1473,editors:[{id:"22844",title:"Prof.",name:"Fausto Pedro",middleName:null,surname:"García Márquez",slug:"fausto-pedro-garcia-marquez",fullName:"Fausto Pedro García Márquez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"95",title:"Applications and Experiences of Quality Control",subtitle:null,isOpenForSubmission:!1,hash:"4bcb22b1eee68210a977a97d5a0f363a",slug:"applications-and-experiences-of-quality-control",bookSignature:"Ognyan Ivanov",coverURL:"https://cdn.intechopen.com/books/images_new/95.jpg",publishedDate:"April 26th 2011",numberOfDownloads:318571,editors:[{id:"22230",title:"Prof.",name:"Ognyan",middleName:null,surname:"Ivanov",slug:"ognyan-ivanov",fullName:"Ognyan Ivanov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"2160",title:"MATLAB",subtitle:"A Fundamental Tool for Scientific Computing and Engineering Applications - Volume 1",isOpenForSubmission:!1,hash:"dd9c658341fbd264ed4f8d9e6aa8ca29",slug:"matlab-a-fundamental-tool-for-scientific-computing-and-engineering-applications-volume-1",bookSignature:"Vasilios N. Katsikis",coverURL:"https://cdn.intechopen.com/books/images_new/2160.jpg",publishedDate:"September 26th 2012",numberOfDownloads:271836,editors:[{id:"12289",title:"Prof.",name:"Vasilios",middleName:"N.",surname:"Katsikis",slug:"vasilios-katsikis",fullName:"Vasilios Katsikis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3560",title:"Advances in Landscape Architecture",subtitle:null,isOpenForSubmission:!1,hash:"a20614517ec5f7e91188fe8e42832138",slug:"advances-in-landscape-architecture",bookSignature:"Murat Özyavuz",coverURL:"https://cdn.intechopen.com/books/images_new/3560.jpg",publishedDate:"July 1st 2013",numberOfDownloads:243450,editors:[{id:"93073",title:"Dr.",name:"Murat",middleName:null,surname:"Ozyavuz",slug:"murat-ozyavuz",fullName:"Murat Ozyavuz"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10739",title:"Global Decline of Insects",subtitle:null,isOpenForSubmission:!1,hash:"543783652b9092962a8fa4bed38eeb17",slug:"global-decline-of-insects",bookSignature:"Hamadttu Abdel Farag El-Shafie",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg",publishedDate:"July 20th 2022",numberOfDownloads:1582,editors:[{id:"192142",title:"Dr.",name:"Hamadttu",middleName:null,surname:"Abdel Farag El-Shafie",slug:"hamadttu-abdel-farag-el-shafie",fullName:"Hamadttu Abdel Farag El-Shafie"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10911",title:"Higher Education",subtitle:"New Approaches to Accreditation, Digitalization, and Globalization in the Age of Covid",isOpenForSubmission:!1,hash:"223a02337498e535e967174c1f648fbc",slug:"higher-education-new-approaches-to-accreditation-digitalization-and-globalization-in-the-age-of-covid",bookSignature:"Lee Waller and Sharon Waller",coverURL:"https://cdn.intechopen.com/books/images_new/10911.jpg",publishedDate:"July 13th 2022",numberOfDownloads:2082,editors:[{id:"263301",title:"Dr.",name:"Lee",middleName:null,surname:"Waller",slug:"lee-waller",fullName:"Lee Waller"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3568",title:"Recent Advances in Plant in vitro Culture",subtitle:null,isOpenForSubmission:!1,hash:"830bbb601742c85a3fb0eeafe1454c43",slug:"recent-advances-in-plant-in-vitro-culture",bookSignature:"Annarita Leva and Laura M. R. Rinaldi",coverURL:"https://cdn.intechopen.com/books/images_new/3568.jpg",publishedDate:"October 17th 2012",numberOfDownloads:256294,editors:[{id:"142145",title:"Dr.",name:"Annarita",middleName:null,surname:"Leva",slug:"annarita-leva",fullName:"Annarita Leva"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"8452",title:"Organizational Conflict",subtitle:"New Insights",isOpenForSubmission:!1,hash:"96bdaaba38a7850a7e7379aa5a505748",slug:"organizational-conflict-new-insights",bookSignature:"Josiane Fahed-Sreih",coverURL:"https://cdn.intechopen.com/books/images_new/8452.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"103784",title:"Dr.",name:"Josiane",middleName:null,surname:"Fahed-Sreih",slug:"josiane-fahed-sreih",fullName:"Josiane Fahed-Sreih"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10778",title:"Model-Based Control Engineering",subtitle:"Recent Design and Implementations for Varied Applications",isOpenForSubmission:!1,hash:"e39a567d9b6d2a45d0a1d927362c9005",slug:"model-based-control-engineering-recent-design-and-implementations-for-varied-applications",bookSignature:"Umar Zakir Abdul Hamid and Ahmad `Athif Mohd Faudzi",coverURL:"https://cdn.intechopen.com/books/images_new/10778.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"268173",title:"Dr.",name:"Umar Zakir Abdul",middleName:null,surname:"Hamid",slug:"umar-zakir-abdul-hamid",fullName:"Umar Zakir Abdul Hamid"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10780",title:"Current Trends in Orthodontics",subtitle:null,isOpenForSubmission:!1,hash:"badce0e23eb5176fd653b049d5295c0a",slug:"current-trends-in-orthodontics",bookSignature:"Farid Bourzgui",coverURL:"https://cdn.intechopen.com/books/images_new/10780.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"52177",title:"Prof.",name:"Farid",middleName:null,surname:"Bourzgui",slug:"farid-bourzgui",fullName:"Farid Bourzgui"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10793",title:"Molecular Mechanisms in Cancer",subtitle:null,isOpenForSubmission:!1,hash:"3ed2817275edb3de6f5683602314706e",slug:"molecular-mechanisms-in-cancer",bookSignature:"Metin Budak and Rajamanickam Rajkumar",coverURL:"https://cdn.intechopen.com/books/images_new/10793.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"226275",title:"Ph.D.",name:"Metin",middleName:null,surname:"Budak",slug:"metin-budak",fullName:"Metin Budak"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11308",title:"Selected Topics on Infant Feeding",subtitle:null,isOpenForSubmission:!1,hash:"213c3e403327a2919eca1dc5e82a0ec3",slug:"selected-topics-on-infant-feeding",bookSignature:"Isam Jaber AL-Zwaini and Haider Hadi AL-Musawi",coverURL:"https://cdn.intechopen.com/books/images_new/11308.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"30993",title:"Prof.",name:"Isam Jaber",middleName:null,surname:"Al-Zwaini",slug:"isam-jaber-al-zwaini",fullName:"Isam Jaber Al-Zwaini"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11331",title:"Secondary Metabolites",subtitle:"Trends and Reviews",isOpenForSubmission:!1,hash:"7d6274f42d5441e537c5fa744bc84523",slug:"secondary-metabolites-trends-and-reviews",bookSignature:"Ramasamy Vijayakumar and Suresh Selvapuram Sudalaimuthu Raja",coverURL:"https://cdn.intechopen.com/books/images_new/11331.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"176044",title:"Dr.",name:"Ramasamy",middleName:null,surname:"Vijayakumar",slug:"ramasamy-vijayakumar",fullName:"Ramasamy Vijayakumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10820",title:"Data Clustering",subtitle:null,isOpenForSubmission:!1,hash:"086d299ffd05aacd2311c3ca4ebf0d3a",slug:"data-clustering",bookSignature:"Niansheng Tang",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"221831",title:"Prof.",name:"Niansheng",middleName:null,surname:"Tang",slug:"niansheng-tang",fullName:"Niansheng Tang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10827",title:"Oral Health Care",subtitle:"An Important Issue of the Modern Society",isOpenForSubmission:!1,hash:"9a0ceb9ced4598aea3f3723f6dc4ea04",slug:"oral-health-care-an-important-issue-of-the-modern-society",bookSignature:"Lavinia Cosmina Ardelean and Laura Cristina Rusu",coverURL:"https://cdn.intechopen.com/books/images_new/10827.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"180569",title:"Dr.",name:"Lavinia",middleName:null,surname:"Ardelean",slug:"lavinia-ardelean",fullName:"Lavinia Ardelean"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11139",title:"Geochemistry and Mineral Resources",subtitle:null,isOpenForSubmission:!1,hash:"928cebbdce21d9b3f081267b24f12dfb",slug:"geochemistry-and-mineral-resources",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11139.jpg",editedByType:"Edited by",publishedDate:"August 17th 2022",editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"696",title:"Medical Imaging",slug:"medical-imaging",parent:{id:"112",title:"Biomedical Engineering",slug:"engineering-biomedical-engineering"},numberOfBooks:9,numberOfSeries:0,numberOfAuthorsAndEditors:133,numberOfWosCitations:23,numberOfCrossrefCitations:41,numberOfDimensionsCitations:66,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"696",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"10871",title:"Computed-Tomography (CT) Scan",subtitle:null,isOpenForSubmission:!1,hash:"966d8cf74fa27eea1b9cbc9a6ee94993",slug:"computed-tomography-ct-scan",bookSignature:"Reda R. Gharieb",coverURL:"https://cdn.intechopen.com/books/images_new/10871.jpg",editedByType:"Edited by",editors:[{id:"225387",title:"Prof.",name:"Reda R.",middleName:"R.",surname:"Gharieb",slug:"reda-r.-gharieb",fullName:"Reda R. Gharieb"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10870",title:"Ultrasound Imaging",subtitle:"Current Topics",isOpenForSubmission:!1,hash:"2f0bc3733ab226d67fa73759ef0e12ad",slug:"ultrasound-imaging-current-topics",bookSignature:"Felix Okechukwu Erondu",coverURL:"https://cdn.intechopen.com/books/images_new/10870.jpg",editedByType:"Edited by",editors:[{id:"68312",title:"Prof.",name:"Felix",middleName:null,surname:"Okechukwu Erondu",slug:"felix-okechukwu-erondu",fullName:"Felix Okechukwu Erondu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9959",title:"Biomedical Signal and Image Processing",subtitle:null,isOpenForSubmission:!1,hash:"22b87a09bd6df065d78c175235d367c8",slug:"biomedical-signal-and-image-processing",bookSignature:"Yongxia Zhou",coverURL:"https://cdn.intechopen.com/books/images_new/9959.jpg",editedByType:"Edited by",editors:[{id:"259308",title:"Dr.",name:"Yongxia",middleName:null,surname:"Zhou",slug:"yongxia-zhou",fullName:"Yongxia Zhou"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7869",title:"Advanced Endoscopy",subtitle:null,isOpenForSubmission:!1,hash:"92f6ce51b737e9086a6059ab7470eee9",slug:"advanced-endoscopy",bookSignature:"Qiang Yan and Xu Sun",coverURL:"https://cdn.intechopen.com/books/images_new/7869.jpg",editedByType:"Edited by",editors:[{id:"247970",title:"Prof.",name:"Qiang",middleName:null,surname:"Yan",slug:"qiang-yan",fullName:"Qiang Yan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8691",title:"Ultrasound Elastography",subtitle:null,isOpenForSubmission:!1,hash:"fdbf5197352ca0294bfc963ef83d1e00",slug:"ultrasound-elastography",bookSignature:"Monica Lupsor-Platon",coverURL:"https://cdn.intechopen.com/books/images_new/8691.jpg",editedByType:"Edited by",editors:[{id:"208594",title:"Associate Prof.",name:"Monica",middleName:null,surname:"Lupsor-Platon",slug:"monica-lupsor-platon",fullName:"Monica Lupsor-Platon"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8125",title:"Medical Imaging",subtitle:"Principles and Applications",isOpenForSubmission:!1,hash:"e0fa3875d6f66d5ccd8cd3f1444c3fb9",slug:"medical-imaging-principles-and-applications",bookSignature:"Yongxia Zhou",coverURL:"https://cdn.intechopen.com/books/images_new/8125.jpg",editedByType:"Edited by",editors:[{id:"259308",title:"Dr.",name:"Yongxia",middleName:null,surname:"Zhou",slug:"yongxia-zhou",fullName:"Yongxia Zhou"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6429",title:"Medical Imaging and Image-Guided Interventions",subtitle:null,isOpenForSubmission:!1,hash:"b0868ac79e071c96b2fb0cea1c4d4119",slug:"medical-imaging-and-image-guided-interventions",bookSignature:"Ronnie A. Sebro",coverURL:"https://cdn.intechopen.com/books/images_new/6429.jpg",editedByType:"Edited by",editors:[{id:"213468",title:"Dr.",name:"Ronnie",middleName:null,surname:"Sebro",slug:"ronnie-sebro",fullName:"Ronnie Sebro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7255",title:"Endoscopy",subtitle:"Novel Techniques and Recent Advancements",isOpenForSubmission:!1,hash:"be87c3a9cfe1bc2462b5f8e094ae6233",slug:"endoscopy-novel-techniques-and-recent-advancements",bookSignature:"Costin Teodor Streba, Dan Ionut Gheonea and Cristin Constantin Vere",coverURL:"https://cdn.intechopen.com/books/images_new/7255.jpg",editedByType:"Edited by",editors:[{id:"55546",title:"Dr.",name:"Costin",middleName:"Teodor",surname:"Streba",slug:"costin-streba",fullName:"Costin Streba"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6692",title:"Medical and Biological Image Analysis",subtitle:null,isOpenForSubmission:!1,hash:"e75f234a0fc1988d9816a94e4c724deb",slug:"medical-and-biological-image-analysis",bookSignature:"Robert Koprowski",coverURL:"https://cdn.intechopen.com/books/images_new/6692.jpg",editedByType:"Edited by",editors:[{id:"50150",title:"Prof.",name:"Robert",middleName:null,surname:"Koprowski",slug:"robert-koprowski",fullName:"Robert Koprowski"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:9,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"59741",doi:"10.5772/intechopen.74576",title:"Active Contour Based Segmentation Techniques for Medical Image Analysis",slug:"active-contour-based-segmentation-techniques-for-medical-image-analysis",totalDownloads:3508,totalCrossrefCites:25,totalDimensionsCites:44,abstract:"Image processing is a technique which is used to derive information from the images. Segmentation is a section of image processing for the separation or segregation of information from the required target region of the image. There are different techniques used for segmentation of pixels of interest from the image. Active contour is one of the active models in segmentation techniques, which makes use of the energy constraints and forces in the image for separation of region of interest. Active contour defines a separate boundary or curvature for the regions of target object for segmentation. The contour depends on various constraints based on which they are classified into different types such as gradient vector flow, balloon and geometric models. Active contour models are used in various image processing applications specifically in medical image processing. In medical imaging, active contours are used in segmentation of regions from different medical images such as brain CT images, MRI images of different organs, cardiac images and different images of regions in the human body. Active contours can also be used in motion tracking and stereo tracking. Thus, the active contour segmentation is used for the separation of pixels of interest for different image processing.",book:{id:"6692",slug:"medical-and-biological-image-analysis",title:"Medical and Biological Image Analysis",fullTitle:"Medical and Biological Image Analysis"},signatures:"R.J. Hemalatha, T.R. Thamizhvani, A. Josephin Arockia Dhivya,\nJosline Elsa Joseph, Bincy Babu and R. Chandrasekaran",authors:[{id:"238868",title:"Prof.",name:"Hemalatha",middleName:null,surname:"R.J",slug:"hemalatha-r.j",fullName:"Hemalatha R.J"},{id:"242385",title:"Dr.",name:"Chandrasekaran",middleName:null,surname:"R",slug:"chandrasekaran-r",fullName:"Chandrasekaran R"},{id:"242386",title:"Ms.",name:"Thamizhvani",middleName:null,surname:"T.R",slug:"thamizhvani-t.r",fullName:"Thamizhvani T.R"},{id:"242388",title:"Dr.",name:"Josephin Arockia Dhivya",middleName:null,surname:"A",slug:"josephin-arockia-dhivya-a",fullName:"Josephin Arockia Dhivya A"},{id:"242389",title:"Ms.",name:"Josline Elsa",middleName:null,surname:"Joseph",slug:"josline-elsa-joseph",fullName:"Josline Elsa Joseph"},{id:"242390",title:"Ms.",name:"Bincy",middleName:null,surname:"Babu",slug:"bincy-babu",fullName:"Bincy Babu"}]},{id:"67331",doi:"10.5772/intechopen.84360",title:"Research in Medical Imaging Using Image Processing Techniques",slug:"research-in-medical-imaging-using-image-processing-techniques",totalDownloads:4380,totalCrossrefCites:5,totalDimensionsCites:9,abstract:"Medical imaging is the procedure used to attain images of the body parts for medical uses in order to identify or study diseases. There are millions of imaging procedures done every week worldwide. Medical imaging is developing rapidly due to developments in image processing techniques including image recognition, analysis, and enhancement. Image processing increases the percentage and amount of detected tissues. This chapter presents the application of both simple and sophisticated image analysis techniques in the medical imaging field. This chapter also summarizes how to exemplify image interpretation challenges using different image processing algorithms such as k-means, ROI-based segmentation, and watershed techniques.",book:{id:"8125",slug:"medical-imaging-principles-and-applications",title:"Medical Imaging",fullTitle:"Medical Imaging - Principles and Applications"},signatures:"Yousif Mohamed Y. Abdallah and Tariq Alqahtani",authors:[{id:"274452",title:"Dr.",name:"Yousif",middleName:"Mohamed",surname:"Abdallah",slug:"yousif-abdallah",fullName:"Yousif Abdallah"},{id:"294009",title:"Dr.",name:"Tariq",middleName:null,surname:"Alqahtani",slug:"tariq-alqahtani",fullName:"Tariq Alqahtani"}]},{id:"69182",doi:"10.5772/intechopen.89200",title:"The Application of Functional Magnetic Resonance Imaging in Neuropathic Pain",slug:"the-application-of-functional-magnetic-resonance-imaging-in-neuropathic-pain",totalDownloads:924,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"In the past, neuropathic pain has been lacking in ideal imaging research methods, which not only limits our research on the pathogenesis of neuropathic pain but also seriously affects the prognosis of treatments. With the rapid development of fMRI technology, more and more scholars have begun to use fMRI technology in the study of neuropathic pain in recent years. This provides a new idea for revealing the underlining mechanisms of neuropathic pain and improving the clinical treatment concepts. In this chapter, we summarized the recent studies of fMRI in neuropathic pain so that readers can better understand the research status and future research directions.",book:{id:"8125",slug:"medical-imaging-principles-and-applications",title:"Medical Imaging",fullTitle:"Medical Imaging - Principles and Applications"},signatures:"Zhi Dou and Liqiang Yang",authors:[{id:"302075",title:"Ph.D.",name:"Zhi",middleName:null,surname:"Dou",slug:"zhi-dou",fullName:"Zhi Dou"},{id:"310181",title:"Dr.",name:"Liqiang",middleName:null,surname:"Yang",slug:"liqiang-yang",fullName:"Liqiang Yang"}]},{id:"68142",doi:"10.5772/intechopen.88004",title:"Elastometry Indices of Unchanged Liver in Healthy Children",slug:"elastometry-indices-of-unchanged-liver-in-healthy-children",totalDownloads:681,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Two hundred healthy children aged 3–18 years were included in the study to determine liver stiffness indices by means of shear wave elastometry. The difference is significant when we compared shear wave velocity in children aged 3–6 years, on the one hand, and in children aged 7–18 years, on the other (p = 0.001). Liver stiffness indices in boys and girls were not different. As a result, liver stiffness indices in children in various age groups have been obtained, which can be recommended as normal ones for pediatric patients.",book:{id:"8691",slug:"ultrasound-elastography",title:"Ultrasound Elastography",fullTitle:"Ultrasound Elastography"},signatures:"Mikhail Pykov, Natalia Kuzmina, Nikolay Rostovtsev and Alexander Kinzersky",authors:null},{id:"68259",doi:"10.5772/intechopen.88183",title:"2D Shear Wave Elastography for Liver Fibrosis Evaluation",slug:"2d-shear-wave-elastography-for-liver-fibrosis-evaluation",totalDownloads:1218,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"2D shear wave elastography is a technique embedded in ultrasound machines which allows the interrogation of the tissue by acoustic radiation force impulses induced into the tissues by focused ultrasonic beams and captures the propagation of resulting shear waves in real time. Elasticity is displayed using a color-coded image superimposed on a B-mode image, and at the same time, a quantitative estimation of liver stiffness (LS) can be performed in a certain region of interest (ROI). The published data showed a real value of this method for liver stiffness estimation in patients with chronic hepatitis. It has the following advantages: it is integrated into standard ultrasound systems; it is a real-time elastographic method; and it is also feasible in patients with ascites and with large and adjustable size of the ROI that will be evaluated.",book:{id:"8691",slug:"ultrasound-elastography",title:"Ultrasound Elastography",fullTitle:"Ultrasound Elastography"},signatures:"Alina Popescu, Roxana Şirli and Ioan Sporea",authors:null}],mostDownloadedChaptersLast30Days:[{id:"67331",title:"Research in Medical Imaging Using Image Processing Techniques",slug:"research-in-medical-imaging-using-image-processing-techniques",totalDownloads:4382,totalCrossrefCites:5,totalDimensionsCites:9,abstract:"Medical imaging is the procedure used to attain images of the body parts for medical uses in order to identify or study diseases. There are millions of imaging procedures done every week worldwide. Medical imaging is developing rapidly due to developments in image processing techniques including image recognition, analysis, and enhancement. Image processing increases the percentage and amount of detected tissues. This chapter presents the application of both simple and sophisticated image analysis techniques in the medical imaging field. This chapter also summarizes how to exemplify image interpretation challenges using different image processing algorithms such as k-means, ROI-based segmentation, and watershed techniques.",book:{id:"8125",slug:"medical-imaging-principles-and-applications",title:"Medical Imaging",fullTitle:"Medical Imaging - Principles and Applications"},signatures:"Yousif Mohamed Y. Abdallah and Tariq Alqahtani",authors:[{id:"274452",title:"Dr.",name:"Yousif",middleName:"Mohamed",surname:"Abdallah",slug:"yousif-abdallah",fullName:"Yousif Abdallah"},{id:"294009",title:"Dr.",name:"Tariq",middleName:null,surname:"Alqahtani",slug:"tariq-alqahtani",fullName:"Tariq Alqahtani"}]},{id:"65933",title:"The Ionizing Radiation Interaction with Matter, the X-ray Computed Tomography Imaging, the Nuclear Medicine SPECT, PET and PET-CT Tomography Imaging",slug:"the-ionizing-radiation-interaction-with-matter-the-x-ray-computed-tomography-imaging-the-nuclear-med",totalDownloads:1049,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The mechanism of the ionizing radiation interaction with matter is described for heavy charged particles, electrons and photons. Those effects causing energy loss of the radiation with sequential effects of absorption or attenuation are presented. The features of some characteristic detector systems with the relative electronics and the data acquisition system (DAQ) are presented. Those detectors are related with the medical imaging sensor systems. The characteristics of the medical imaging process of the X-ray and nuclear imaging with SPECT, PET and the combination of PET-CT are presented. The computed X-ray tomography, called CT, and the nuclear medicine tomography are presented, implementing the most of the previous parts, as they are defined in PET and SPECT imaging plus the combination of PET with CT the PET-CT.",book:{id:"8125",slug:"medical-imaging-principles-and-applications",title:"Medical Imaging",fullTitle:"Medical Imaging - Principles and Applications"},signatures:"Evangelos Gazis",authors:[{id:"281707",title:"Prof.",name:"Evangelos",middleName:null,surname:"Gazis",slug:"evangelos-gazis",fullName:"Evangelos Gazis"}]},{id:"68830",title:"PET-CT Principles and Applications in Lung Cancer Management",slug:"pet-ct-principles-and-applications-in-lung-cancer-management",totalDownloads:1132,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Lung cancer is the most common malignant cancer throughout the world; the positron emission tomography/computed tomography (PET-CT) combines both the metabolism information from PET and anatomy details from CT, which is the state of the art. This manuscript introduced the PET-CT and applications in lung cancer diagnosing, staging, and treatment. Several aspects including clinical features, classification, grading and pathology of the lung cancer, principles of PET-CT, and evaluation of diagnosing and treatment had been covered. Detailed demonstration of each cancer subtype, staging criteria, and classification was described. The content will benefit the clinical doctors as well as radiologists.",book:{id:"8125",slug:"medical-imaging-principles-and-applications",title:"Medical Imaging",fullTitle:"Medical Imaging - Principles and Applications"},signatures:"Long Chen, Hua Sun and Yunchao Huang",authors:[{id:"278386",title:"Ph.D.",name:"Long",middleName:null,surname:"Chen",slug:"long-chen",fullName:"Long Chen"},{id:"280160",title:"Prof.",name:"Yunchao",middleName:null,surname:"Huang",slug:"yunchao-huang",fullName:"Yunchao Huang"},{id:"280161",title:"Prof.",name:"Hua",middleName:null,surname:"Sun",slug:"hua-sun",fullName:"Hua Sun"}]},{id:"64352",title:"Endoscopic Dacryocystorhinostomy",slug:"endoscopic-dacryocystorhinostomy-1",totalDownloads:5950,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Epiphora, or abnormal tearing, occurs because of the blockage in the lacrimal drainage system, which impairs normal tearing channeling into the nose. It is essential that with proper history and examination including syringing and probing, a correct diagnosis is made. Syringing and probing are performed only in congenital and acquired nasolacrimal duct obstruction (NLDO). Dacryocystorhinostomy (DCR) is a procedure performed for the treatment of tearing (epiphora) due to blockage of the nasolacrimal drainage system. Endoscopic dacryocystorhinostomy (E-DCR) using telescopes has gained a lot of momentum among otolaryngologists, since the outcomes are comparable to the external approach. Advances in surgical technique and a better understanding of the anatomy have resulted in improvements in outcomes. The anatomy of the lacrimal system will be discussed in detail including the surgical indications and techniques of DCR. The advantages, results, and complications of surgery will be highlighted.",book:{id:"7255",slug:"endoscopy-novel-techniques-and-recent-advancements",title:"Endoscopy",fullTitle:"Endoscopy - Novel Techniques and Recent Advancements"},signatures:"Balwant Singh Gendeh",authors:[{id:"67669",title:null,name:"Balwant Singh",middleName:null,surname:"Gendeh",slug:"balwant-singh-gendeh",fullName:"Balwant Singh Gendeh"}]},{id:"59741",title:"Active Contour Based Segmentation Techniques for Medical Image Analysis",slug:"active-contour-based-segmentation-techniques-for-medical-image-analysis",totalDownloads:3514,totalCrossrefCites:25,totalDimensionsCites:44,abstract:"Image processing is a technique which is used to derive information from the images. Segmentation is a section of image processing for the separation or segregation of information from the required target region of the image. There are different techniques used for segmentation of pixels of interest from the image. Active contour is one of the active models in segmentation techniques, which makes use of the energy constraints and forces in the image for separation of region of interest. Active contour defines a separate boundary or curvature for the regions of target object for segmentation. The contour depends on various constraints based on which they are classified into different types such as gradient vector flow, balloon and geometric models. Active contour models are used in various image processing applications specifically in medical image processing. In medical imaging, active contours are used in segmentation of regions from different medical images such as brain CT images, MRI images of different organs, cardiac images and different images of regions in the human body. Active contours can also be used in motion tracking and stereo tracking. Thus, the active contour segmentation is used for the separation of pixels of interest for different image processing.",book:{id:"6692",slug:"medical-and-biological-image-analysis",title:"Medical and Biological Image Analysis",fullTitle:"Medical and Biological Image Analysis"},signatures:"R.J. Hemalatha, T.R. Thamizhvani, A. Josephin Arockia Dhivya,\nJosline Elsa Joseph, Bincy Babu and R. Chandrasekaran",authors:[{id:"238868",title:"Prof.",name:"Hemalatha",middleName:null,surname:"R.J",slug:"hemalatha-r.j",fullName:"Hemalatha R.J"},{id:"242385",title:"Dr.",name:"Chandrasekaran",middleName:null,surname:"R",slug:"chandrasekaran-r",fullName:"Chandrasekaran R"},{id:"242386",title:"Ms.",name:"Thamizhvani",middleName:null,surname:"T.R",slug:"thamizhvani-t.r",fullName:"Thamizhvani T.R"},{id:"242388",title:"Dr.",name:"Josephin Arockia Dhivya",middleName:null,surname:"A",slug:"josephin-arockia-dhivya-a",fullName:"Josephin Arockia Dhivya A"},{id:"242389",title:"Ms.",name:"Josline Elsa",middleName:null,surname:"Joseph",slug:"josline-elsa-joseph",fullName:"Josline Elsa Joseph"},{id:"242390",title:"Ms.",name:"Bincy",middleName:null,surname:"Babu",slug:"bincy-babu",fullName:"Bincy Babu"}]}],onlineFirstChaptersFilter:{topicId:"696",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"82625",title:"Role of Elastography in the Evaluation of Parathyroid Disease",slug:"role-of-elastography-in-the-evaluation-of-parathyroid-disease",totalDownloads:5,totalDimensionsCites:0,doi:"10.5772/intechopen.105923",abstract:"Primary hyperparathyroidism is a prevalent disease of the parathyroid glands and the third most common endocrinopathy, especially among postmenopausal women. Secondary hyperparathyroidism is a compensatory response to hypocalcemic states due to chronic renal disease, vitamin D deficiency and malabsorption syndromes, and other chronic illnesses. Elastography can be an effective tool in localizing and identifying parathyroid lesions, whether it is a parathyroid adenoma or hyperplastic parathyroid secondary to chronic kidney disease, by differentiating between possible parathyroid lesions and thyroid nodules, cervical lymph nodes, or other anatomical structures. No current guidelines recommendations are available and no established general cutoff values on the elasticity of parathyroid lesions. We have conducted several prospective studies on primary and secondary hyperparathyroidism, using ultrasound imaging and elastography, shear wave, and strain elastography to better identify the parathyroid lesions and improve the preoperative localization and diagnostic. The results were encouraging, allowing us to determine cutoff values that are different for lesions from primary hyperparathyroidism and secondary hyperparathyroidism and comparing them with normal thyroid tissue and surrounding muscle tissue.",book:{id:"11250",title:"Elastography - Applications in Clinical Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11250.jpg"},signatures:"Dana Amzar, Laura Cotoi, Andreea Borlea, Calin Adela, Gheorghe Nicusor Pop and Dana Stoian"},{id:"82408",title:"The Place of Liver Elastography in Diagnosis of Alcohol-Related Liver Disease",slug:"the-place-of-liver-elastography-in-diagnosis-of-alcohol-related-liver-disease",totalDownloads:12,totalDimensionsCites:0,doi:"10.5772/intechopen.105691",abstract:"Harmful use of alcohol is associated with more than 200 diseases and types of injuries, the liver being one of the most important targets. Alcoholic liver disease (ALD) is the most frequent cause of severe chronic liver disease in Europe and worldwide. ALD can progress from alcoholic fatty liver to alcoholic steatohepatitis and alcoholic liver cirrhosis, the grade of fibrosis being the key prognostic factor for the severity of the diseases. This chapter will present the place of liver elastography in the noninvasive assessment of ALD. It will describe the data available in the literature regarding the different elastography techniques for liver stiffness assessment and also the potential of these techniques for screening ALD.",book:{id:"11250",title:"Elastography - Applications in Clinical Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11250.jpg"},signatures:"Alina Popescu and Camelia Foncea"},{id:"81698",title:"Shear Wave Elastography in the Assessment of Liver Changes in Children with Cystic Fibrosis",slug:"shear-wave-elastography-in-the-assessment-of-liver-changes-in-children-with-cystic-fibrosis",totalDownloads:4,totalDimensionsCites:0,doi:"10.5772/intechopen.103185",abstract:"A standard ultrasound examination of the liver was performed in 232 children. It was supplemented by a two-dimensional shear wave elastography. There were 200 healthy children aged 3 to 18 years (control group) and 32 patients with cystic fibrosis aged 2 to 17 years (study group) among them. The procedure was carried out by means of Aixplorer device (Supersonic Imagine, France) using a convex sensor operating in the 1–6 MHz frequency range. Ten measurements of Young modulus values were carried out in different segments of the right lobe of the liver followed by data averaging. In patients with cystic fibrosis, the values of Young modulus were significantly higher than in healthy children (Emean median: 6.50 and 5.00 kPa, interquartile range: 5.62–7.52 and 4.70–5.38 kPa, respectively (p < 0.001). In patients with severe cystic fibrosis, the values of Young modulus were significantly higher compared to patients suffering from moderate disease (Emean median: 7.30 and 5.90 kPa, interquartile range: 6.20–10.70 and 5.20–6.75 kPa, respectively (p < 0.002). Shear wave elastography is a non-invasive technique that can be successfully used in a comprehensive ultrasound assessment of the liver in children with cystic fibrosis to facilitate the diagnosis and monitoring of fibrous changes.",book:{id:"11250",title:"Elastography - Applications in Clinical Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11250.jpg"},signatures:"Mikhail Pykov, Natalia Kuzmina and Nikolay Rostovtsev"},{id:"81625",title:"Endoscopic Ultrasound Elastography: New Advancement in Pancreatic Diseases",slug:"endoscopic-ultrasound-elastography-new-advancement-in-pancreatic-diseases",totalDownloads:20,totalDimensionsCites:0,doi:"10.5772/intechopen.103890",abstract:"Elastography opened up new frontiers for pancreatic disease, as it may aid in tumor mass differentiation. Ultrasound strain elastography and ultrasound shear-wave elastography have been used so far by transabdominal transducers. New technological advancements have embedded elastography techniques in endoscopic ultrasound (EUS), thus enabling a better evaluation of patients with pancreatic tumors, chronic pancreatitis, autoimmune pancreatitis, gastrointestinal subepithelial lesions, and lymph node involvement. Moreover, EUS-E might help in guiding EUS-Fine Needle Aspiration or EUS-Fine Needle Biopsy when addressing solid pancreatic tumors, for proper tissue harvesting. Furthermore, artificial intelligence methods may bypass the human factor and lead to better diagnostic results.",book:{id:"11250",title:"Elastography - Applications in Clinical Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11250.jpg"},signatures:"Bogdan Silviu Ungureanu and Adrian Saftoiu"},{id:"81380",title:"Elastography Methods in the Prediction of Malignancy in Thyroid Nodules",slug:"elastography-methods-in-the-prediction-of-malignancy-in-thyroid-nodules",totalDownloads:14,totalDimensionsCites:0,doi:"10.5772/intechopen.104261",abstract:"Ultrasonography provides a primary stratification of the malignancy risk of thyroid nodules for selecting those that need further evaluation by fine-needle aspiration cytology (FNAC). Ultrasound elastography (USE) methods have been more recently proposed as a promising tool, aiming to increase the accuracy of baseline ultrasound. By means of USE, stiffness is assessed as an indicator of malignancy. Strain elastography was the first method used in thyroid imaging, with very good accuracy in discerning thyroid cancer. More recently, 2D shear-wave elastography also confirmed to be a valuable tool with similar outcomes. The advantages, limitations, and technical details of the elastography methods currently used in assessing thyroid morphology, particularly thyroid nodules, will be presented and compared in this chapter.",book:{id:"11250",title:"Elastography - Applications in Clinical Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11250.jpg"},signatures:"Andreea Borlea, Laura Cotoi, Corina Paul, Felix Bende and Dana Stoian"},{id:"81210",title:"The Place of Elastography for Liver Tumors Assessment",slug:"the-place-of-elastography-for-liver-tumors-assessment",totalDownloads:21,totalDimensionsCites:0,doi:"10.5772/intechopen.103777",abstract:"Elastography is an ultrasound (US) based method widely used in the field of hepatology, particularly for liver stiffness assessment in patients with chronic liver disease. Elastography brings valuable information regarding tissue stiffness and could be considered a virtual biopsy. In the last years, the incidence of focal liver lesions (FLLs) has increased due to frequent detection during a routine abdominal US. The differential diagnosis of FLLs can be challenging, and it is important in terms of treatment options and prognosis. Currently, most FLLs require for diagnosis workup imaging methods with contrast (radiation exposure, potentially nephrotoxic contrast agents) and/or biopsy that are considered invasive procedures and could be contraindicated in particular cases. Avoidance of these invasive methods could be the main reason to perform elastography for FLLs evaluation as they are commonly first detected on US examination. Several studies showed that elastography could bring additional information regarding the stiffness of FLLs in order to predict their nature.",book:{id:"11250",title:"Elastography - Applications in Clinical Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11250.jpg"},signatures:"Ana-Maria Ghiuchici and Mirela Dănilă"}],onlineFirstChaptersTotal:16},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:11,numberOfPublishedChapters:91,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:333,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:11,numberOfPublishedChapters:144,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:124,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:23,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:12,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"13",title:"Veterinary Medicine and Science",doi:"10.5772/intechopen.73681",issn:"2632-0517",scope:"Paralleling similar advances in the medical field, astounding advances occurred in Veterinary Medicine and Science in recent decades. These advances have helped foster better support for animal health, more humane animal production, and a better understanding of the physiology of endangered species to improve the assisted reproductive technologies or the pathogenesis of certain diseases, where animals can be used as models for human diseases (like cancer, degenerative diseases or fertility), and even as a guarantee of public health. Bridging Human, Animal, and Environmental health, the holistic and integrative “One Health” concept intimately associates the developments within those fields, projecting its advancements into practice. This book series aims to tackle various animal-related medicine and sciences fields, providing thematic volumes consisting of high-quality significant research directed to researchers and postgraduates. It aims to give us a glimpse into the new accomplishments in the Veterinary Medicine and Science field. By addressing hot topics in veterinary sciences, we aim to gather authoritative texts within each issue of this series, providing in-depth overviews and analysis for graduates, academics, and practitioners and foreseeing a deeper understanding of the subject. Forthcoming texts, written and edited by experienced researchers from both industry and academia, will also discuss scientific challenges faced today in Veterinary Medicine and Science. In brief, we hope that books in this series will provide accessible references for those interested or working in this field and encourage learning in a range of different topics.",coverUrl:"https://cdn.intechopen.com/series/covers/13.jpg",latestPublicationDate:"August 17th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:11,editor:{id:"38652",title:"Prof.",name:"Rita",middleName:null,surname:"Payan-Carreira",slug:"rita-payan-carreira",fullName:"Rita Payan-Carreira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRiFPQA0/Profile_Picture_1614601496313",biography:"Rita Payan Carreira earned her Veterinary Degree from the Faculty of Veterinary Medicine in Lisbon, Portugal, in 1985. She obtained her Ph.D. in Veterinary Sciences from the University of Trás-os-Montes e Alto Douro, Portugal. After almost 32 years of teaching at the University of Trás-os-Montes and Alto Douro, she recently moved to the University of Évora, Department of Veterinary Medicine, where she teaches in the field of Animal Reproduction and Clinics. Her primary research areas include the molecular markers of the endometrial cycle and the embryo–maternal interaction, including oxidative stress and the reproductive physiology and disorders of sexual development, besides the molecular determinants of male and female fertility. She often supervises students preparing their master's or doctoral theses. She is also a frequent referee for various journals.",institutionString:null,institution:{name:"University of Évora",institutionURL:null,country:{name:"Portugal"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:3,paginationItems:[{id:"19",title:"Animal Science",coverUrl:"https://cdn.intechopen.com/series_topics/covers/19.jpg",isOpenForSubmission:!0,editor:{id:"259298",title:"Dr.",name:"Edward",middleName:null,surname:"Narayan",slug:"edward-narayan",fullName:"Edward Narayan",profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",biography:"Dr. Edward Narayan graduated with Ph.D. degree in Biology from the University of the South Pacific and pioneered non-invasive reproductive and stress endocrinology tools for amphibians - the novel development and validation of non-invasive enzyme immunoassays for the evaluation of reproductive hormonal cycle and stress hormone responses to environmental stressors. \nDr. Narayan leads the Stress Lab (Comparative Physiology and Endocrinology) at the University of Queensland. A dynamic career research platform which is based on the thematic areas of comparative vertebrate physiology, stress endocrinology, reproductive endocrinology, animal health and welfare, and conservation biology. \nEdward has supervised 40 research students and published over 60 peer reviewed research.",institutionString:null,institution:{name:"University of Queensland",institutionURL:null,country:{name:"Australia"}}},editorTwo:null,editorThree:null},{id:"20",title:"Animal Nutrition",coverUrl:"https://cdn.intechopen.com/series_topics/covers/20.jpg",isOpenForSubmission:!0,editor:{id:"175967",title:"Dr.",name:"Manuel",middleName:null,surname:"Gonzalez Ronquillo",slug:"manuel-gonzalez-ronquillo",fullName:"Manuel Gonzalez Ronquillo",profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",biography:"Dr. Manuel González Ronquillo obtained his doctorate degree from the University of Zaragoza, Spain, in 2001. He is a research professor at the Faculty of Veterinary Medicine and Animal Husbandry, Autonomous University of the State of Mexico. He is also a level-2 researcher. He received a Fulbright-Garcia Robles fellowship for a postdoctoral stay at the US Dairy Forage Research Center, Madison, Wisconsin, USA in 2008–2009. He received grants from Alianza del Pacifico for a stay at the University of Magallanes, Chile, in 2014, and from Consejo Nacional de Ciencia y Tecnología (CONACyT) to work in the Food and Agriculture Organization’s Animal Production and Health Division (AGA), Rome, Italy, in 2014–2015. He has collaborated with researchers from different countries and published ninety-eight journal articles. He teaches various degree courses in zootechnics, sheep production, and agricultural sciences and natural resources.\n\nDr. Ronquillo’s research focuses on the evaluation of sustainable animal diets (StAnD), using native resources of the region, decreasing carbon footprint, and applying meta-analysis and mathematical models for a better understanding of animal production.",institutionString:null,institution:{name:"Universidad Autónoma del Estado de México",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null},{id:"28",title:"Animal Reproductive Biology and Technology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/28.jpg",isOpenForSubmission:!0,editor:{id:"177225",title:"Prof.",name:"Rosa Maria Lino Neto",middleName:null,surname:"Pereira",slug:"rosa-maria-lino-neto-pereira",fullName:"Rosa Maria Lino Neto Pereira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9wkQAC/Profile_Picture_1624519982291",biography:"Rosa Maria Lino Neto Pereira (DVM, MsC, PhD and) is currently a researcher at the Genetic Resources and Biotechnology Unit of the National Institute of Agrarian and Veterinarian Research (INIAV, Portugal). She is the head of the Reproduction and Embryology Laboratories and was lecturer of Reproduction and Reproductive Biotechnologies at Veterinary Medicine Faculty. She has over 25 years of experience working in reproductive biology and biotechnology areas with a special emphasis on embryo and gamete cryopreservation, for research and animal genetic resources conservation, leading research projects with several peer-reviewed papers. Rosa Pereira is member of the ERFP-FAO Ex situ Working Group and of the Management Commission of the Portuguese Animal Germplasm Bank.",institutionString:"The National Institute for Agricultural and Veterinary Research. Portugal",institution:null},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:21,paginationItems:[{id:"83115",title:"Fungi and Oomycetes–Allies in Eliminating Environmental Pathogens",doi:"10.5772/intechopen.106498",signatures:"Iasmina Luca",slug:"fungi-and-oomycetes-allies-in-eliminating-environmental-pathogens",totalDownloads:0,totalCrossrefCites:0,totalDimensionsCites:null,authors:null,book:{title:"Animal Welfare - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11579.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82991",title:"Diseases of the Canine Prostate Gland",doi:"10.5772/intechopen.105835",signatures:"Sabine Schäfer-Somi",slug:"diseases-of-the-canine-prostate-gland",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82956",title:"Potential Substitutes of Antibiotics for Swine and Poultry Production",doi:"10.5772/intechopen.106081",signatures:"Ho Trung Thong, Le Nu Anh Thu and Ho Viet Duc",slug:"potential-substitutes-of-antibiotics-for-swine-and-poultry-production",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Antibiotics and Probiotics in Animal Food - Impact and Regulation",coverURL:"https://cdn.intechopen.com/books/images_new/11578.jpg",subseries:{id:"20",title:"Animal Nutrition"}}},{id:"82905",title:"A Review of Application Strategies and Efficacy of Probiotics in Pet Food",doi:"10.5772/intechopen.105829",signatures:"Heather Acuff and Charles G. Aldrich",slug:"a-review-of-application-strategies-and-efficacy-of-probiotics-in-pet-food",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Antibiotics and Probiotics in Animal Food - Impact and Regulation",coverURL:"https://cdn.intechopen.com/books/images_new/11578.jpg",subseries:{id:"20",title:"Animal Nutrition"}}}]},overviewPagePublishedBooks:{paginationCount:11,paginationItems:[{type:"book",id:"7233",title:"New Insights into Theriogenology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7233.jpg",slug:"new-insights-into-theriogenology",publishedDate:"December 5th 2018",editedByType:"Edited by",bookSignature:"Rita Payan-Carreira",hash:"74f4147e3fb214dd050e5edd3aaf53bc",volumeInSeries:1,fullTitle:"New Insights into Theriogenology",editors:[{id:"38652",title:"Prof.",name:"Rita",middleName:null,surname:"Payan-Carreira",slug:"rita-payan-carreira",fullName:"Rita Payan-Carreira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRiFPQA0/Profile_Picture_1614601496313",biography:"Rita Payan Carreira earned her Veterinary Degree from the Faculty of Veterinary Medicine in Lisbon, Portugal, in 1985. She obtained her Ph.D. in Veterinary Sciences from the University of Trás-os-Montes e Alto Douro, Portugal. After almost 32 years of teaching at the University of Trás-os-Montes and Alto Douro, she recently moved to the University of Évora, Department of Veterinary Medicine, where she teaches in the field of Animal Reproduction and Clinics. Her primary research areas include the molecular markers of the endometrial cycle and the embryo–maternal interaction, including oxidative stress and the reproductive physiology and disorders of sexual development, besides the molecular determinants of male and female fertility. She often supervises students preparing their master's or doctoral theses. She is also a frequent referee for various journals.",institutionString:null,institution:{name:"University of Évora",institutionURL:null,country:{name:"Portugal"}}}]},{type:"book",id:"7144",title:"Veterinary Anatomy and Physiology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7144.jpg",slug:"veterinary-anatomy-and-physiology",publishedDate:"March 13th 2019",editedByType:"Edited by",bookSignature:"Catrin Sian Rutland and Valentina Kubale",hash:"75cdacb570e0e6d15a5f6e69640d87c9",volumeInSeries:2,fullTitle:"Veterinary Anatomy and Physiology",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",biography:"Catrin Rutland is an Associate Professor of Anatomy and Developmental Genetics at the University of Nottingham, UK. She obtained a BSc from the University of Derby, England, a master’s degree from Technische Universität München, Germany, and a Ph.D. from the University of Nottingham. She undertook a post-doctoral research fellowship in the School of Medicine before accepting tenure in Veterinary Medicine and Science. Dr. Rutland also obtained an MMedSci (Medical Education) and a Postgraduate Certificate in Higher Education (PGCHE). She is the author of more than sixty peer-reviewed journal articles, twelve books/book chapters, and more than 100 research abstracts in cardiovascular biology and oncology. She is a board member of the European Association of Veterinary Anatomists, Fellow of the Anatomical Society, and Senior Fellow of the Higher Education Academy. Dr. Rutland has also written popular science books for the public. https://orcid.org/0000-0002-2009-4898. www.nottingham.ac.uk/vet/people/catrin.rutland",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}]},{type:"book",id:"8524",title:"Lactation in Farm Animals",subtitle:"Biology, Physiological Basis, Nutritional Requirements, and Modelization",coverURL:"https://cdn.intechopen.com/books/images_new/8524.jpg",slug:"lactation-in-farm-animals-biology-physiological-basis-nutritional-requirements-and-modelization",publishedDate:"January 22nd 2020",editedByType:"Edited by",bookSignature:"Naceur M'Hamdi",hash:"2aa2a9a0ec13040bbf0455e34625504e",volumeInSeries:3,fullTitle:"Lactation in Farm Animals - Biology, Physiological Basis, Nutritional Requirements, and Modelization",editors:[{id:"73376",title:"Dr.",name:"Naceur",middleName:null,surname:"M'Hamdi",slug:"naceur-m'hamdi",fullName:"Naceur M'Hamdi",profilePictureURL:"https://mts.intechopen.com/storage/users/73376/images/system/73376.jpg",biography:"Naceur M’HAMDI is Associate Professor at the National Agronomic Institute of Tunisia, University of Carthage. He is also Member of the Laboratory of genetic, animal and feed resource and member of Animal science Department of INAT. He graduated from Higher School of Agriculture of Mateur, University of Carthage, in 2002 and completed his masters in 2006. Dr. M’HAMDI completed his PhD thesis in Genetic welfare indicators of dairy cattle at Higher Institute of Agronomy of Chott-Meriem, University of Sousse, in 2011. He worked as assistant Professor of Genetic, biostatistics and animal biotechnology at INAT since 2013.",institutionString:null,institution:null}]},{type:"book",id:"8460",title:"Reproductive Biology and Technology in Animals",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8460.jpg",slug:"reproductive-biology-and-technology-in-animals",publishedDate:"April 15th 2020",editedByType:"Edited by",bookSignature:"Juan Carlos Gardón Poggi and Katy Satué Ambrojo",hash:"32ef5fe73998dd723d308225d756fa1e",volumeInSeries:4,fullTitle:"Reproductive Biology and Technology in Animals",editors:[{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón Poggi",slug:"juan-carlos-gardon-poggi",fullName:"Juan Carlos Gardón Poggi",profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",biography:"Juan Carlos Gardón Poggi received University degree from the Faculty of Agrarian Science in Argentina, in 1983. Also he received Masters Degree and PhD from Córdoba University, Spain. He is currently a Professor at the Catholic University of Valencia San Vicente Mártir, at the Department of Medicine and Animal Surgery. He teaches diverse courses in the field of Animal Reproduction and he is the Director of the Veterinary Farm. He also participates in academic postgraduate activities at the Veterinary Faculty of Murcia University, Spain. His research areas include animal physiology, physiology and biotechnology of reproduction either in males or females, the study of gametes under in vitro conditions and the use of ultrasound as a complement to physiological studies and development of applied biotechnologies. Routinely, he supervises students preparing their doctoral, master thesis or final degree projects.",institutionString:null,institution:{name:"Valencia Catholic University Saint Vincent Martyr",institutionURL:null,country:{name:"Spain"}}}]}]},openForSubmissionBooks:{paginationCount:2,paginationItems:[{id:"12141",title:"Leadership - Advancing Great Leadership Practices and Good Leaders",coverURL:"https://cdn.intechopen.com/books/images_new/12141.jpg",hash:"85f77453916f1d80d80d88ee4fd2f2d1",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 1st 2022",isOpenForSubmission:!0,editors:[{id:"420133",title:"Dr.",name:"Joseph",surname:"Crawford",slug:"joseph-crawford",fullName:"Joseph Crawford"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12139",title:"Global Market and Trade",coverURL:"https://cdn.intechopen.com/books/images_new/12139.jpg",hash:"fa34af07c3a9657fa670404202f8cba5",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 21st 2022",isOpenForSubmission:!0,editors:[{id:"243649",title:"Dr.Ing.",name:"Ireneusz",surname:"Miciuła",slug:"ireneusz-miciula",fullName:"Ireneusz Miciuła"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:21,paginationItems:[{id:"83000",title:"Purine and Pyrimidine Pathways as Antimalarial Targets",doi:"10.5772/intechopen.106468",signatures:"Yacoba V.T. Minnow and Vern L. Schramm",slug:"purine-and-pyrimidine-pathways-as-antimalarial-targets",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Malaria - Recent Advances, and New Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11576.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"83065",title:"Interventions and Practical Approaches to Reduce the Burden of Malaria on School-Aged Children",doi:"10.5772/intechopen.106469",signatures:"Andrew Macnab",slug:"interventions-and-practical-approaches-to-reduce-the-burden-of-malaria-on-school-aged-children",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Andrew",surname:"Macnab"}],book:{title:"Malaria - Recent Advances, and New Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11576.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"82804",title:"Psychiatric Problems in HIV Care",doi:"10.5772/intechopen.106077",signatures:"Seggane Musisi and Noeline Nakasujja",slug:"psychiatric-problems-in-hiv-care",totalDownloads:2,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Future Opportunities and Tools for Emerging Challenges for HIV/AIDS Control",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82827",title:"Epidemiology and Control of Schistosomiasis",doi:"10.5772/intechopen.105170",signatures:"Célestin Kyambikwa Bisangamo",slug:"epidemiology-and-control-of-schistosomiasis",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"New Horizons for Schistosomiasis Research",coverURL:"https://cdn.intechopen.com/books/images_new/10829.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"82817",title:"Perspective Chapter: Microfluidic Technologies for On-Site Detection and Quantification of Infectious Diseases - The Experience with SARS-CoV-2/COVID-19",doi:"10.5772/intechopen.105950",signatures:"Andres Escobar and Chang-qing Xu",slug:"perspective-chapter-microfluidic-technologies-for-on-site-detection-and-quantification-of-infectious",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"SARS-CoV-2 Variants - Two Years After",coverURL:"https://cdn.intechopen.com/books/images_new/11573.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82667",title:"Perspective Chapter: Analysis of SARS-CoV-2 Indirect Spreading Routes and Possible Countermeasures",doi:"10.5772/intechopen.105914",signatures:"Cesare Saccani, Marco Pellegrini and Alessandro Guzzini",slug:"perspective-chapter-analysis-of-sars-cov-2-indirect-spreading-routes-and-possible-countermeasures",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"SARS-CoV-2 Variants - Two Years After",coverURL:"https://cdn.intechopen.com/books/images_new/11573.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82559",title:"Perspective Chapter: Bioinformatics Study of the Evolution of SARS-CoV-2 Spike Protein",doi:"10.5772/intechopen.105915",signatures:"Črtomir Podlipnik, Radostina Alexandrova, Sebastian Pleško, Urban Bren and Marko Jukič",slug:"perspective-chapter-bioinformatics-study-of-the-evolution-of-sars-cov-2-spike-protein",totalDownloads:20,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"SARS-CoV-2 Variants - Two Years After",coverURL:"https://cdn.intechopen.com/books/images_new/11573.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82521",title:"Challenges in Platelet Functions in HIV/AIDS Management",doi:"10.5772/intechopen.105731",signatures:"Gordon Ogweno",slug:"challenges-in-platelet-functions-in-hiv-aids-management",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Future Opportunities and Tools for Emerging Challenges for HIV/AIDS Control",coverURL:"https://cdn.intechopen.com/books/images_new/11575.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}},{id:"82701",title:"Pathology of Streptococcal Infections",doi:"10.5772/intechopen.105814",signatures:"Yutaka Tsutsumi",slug:"pathology-of-streptococcal-infections",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Yutaka",surname:"Tsutsumi"}],book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"82634",title:"Bacterial Sexually Transmitted Disease",doi:"10.5772/intechopen.105747",signatures:"Lebeza Alemu Tenaw",slug:"bacterial-sexually-transmitted-disease",totalDownloads:12,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Bacterial Sexually Transmitted Infections - New Findings, Diagnosis, Treatment, and Prevention",coverURL:"https://cdn.intechopen.com/books/images_new/11569.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}}]},subseriesFiltersForOFChapters:[{caption:"Fungal Infectious Diseases",value:4,count:1,group:"subseries"},{caption:"Parasitic Infectious Diseases",value:5,count:5,group:"subseries"},{caption:"Bacterial Infectious Diseases",value:3,count:5,group:"subseries"},{caption:"Viral Infectious Diseases",value:6,count:10,group:"subseries"}],publishedBooks:{paginationCount:1,paginationItems:[{type:"book",id:"10843",title:"Persistent Organic Pollutants (POPs)",subtitle:"Monitoring, Impact and Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10843.jpg",slug:"persistent-organic-pollutants-pops-monitoring-impact-and-treatment",publishedDate:"April 13th 2022",editedByType:"Edited by",bookSignature:"Mohamed Nageeb Rashed",hash:"f5b1589f0a990b6114fef2dadc735dd9",volumeInSeries:1,fullTitle:"Persistent Organic Pollutants (POPs) - Monitoring, Impact and Treatment",editors:[{id:"63465",title:"Prof.",name:"Mohamed Nageeb",middleName:null,surname:"Rashed",slug:"mohamed-nageeb-rashed",fullName:"Mohamed Nageeb Rashed",profilePictureURL:"https://mts.intechopen.com/storage/users/63465/images/system/63465.gif",institutionString:null,institution:{name:"Aswan University",institutionURL:null,country:{name:"Egypt"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Pollution",value:38,count:1}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:1}],authors:{paginationCount:303,paginationItems:[{id:"280338",title:"Dr.",name:"Yutaka",middleName:null,surname:"Tsutsumi",slug:"yutaka-tsutsumi",fullName:"Yutaka Tsutsumi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/280338/images/7961_n.jpg",biography:null,institutionString:null,institution:{name:"Fujita Health University",country:{name:"Japan"}}},{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/116250/images/system/116250.jpg",biography:"Professor Nima Rezaei obtained an MD from Tehran University of Medical Sciences, Iran. He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. Govindarajan completed his BSc degree in Zoology at Government Arts College (Autonomous), Kumbakonam, and MSc, MPhil, and PhD degrees at Annamalai University, Annamalai Nagar, Tamil Nadu, India. He is serving as an assistant professor at the Department of Zoology, Annamalai University. His research interests include isolation, identification, and characterization of biologically active molecules from plants and microbes. He has identified more than 20 pure compounds with high mosquitocidal activity and also conducted high-quality research on photochemistry and nanosynthesis. He has published more than 150 studies in journals with impact factor and 2 books in Lambert Academic Publishing, Germany. He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"117248",title:"Dr.",name:"Andrew",middleName:null,surname:"Macnab",slug:"andrew-macnab",fullName:"Andrew Macnab",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"322007",title:"Dr.",name:"Maria Elizbeth",middleName:null,surname:"Alvarez-Sánchez",slug:"maria-elizbeth-alvarez-sanchez",fullName:"Maria Elizbeth Alvarez-Sánchez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",country:{name:"Mexico"}}},{id:"337443",title:"Dr.",name:"Juan",middleName:null,surname:"A. Gonzalez-Sanchez",slug:"juan-a.-gonzalez-sanchez",fullName:"Juan A. Gonzalez-Sanchez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico System",country:{name:"United States of America"}}},{id:"337446",title:"Dr.",name:"Maria",middleName:null,surname:"Zavala-Colon",slug:"maria-zavala-colon",fullName:"Maria Zavala-Colon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico, Medical Sciences Campus",country:{name:"United States of America"}}}]}},subseries:{item:{id:"24",type:"subseries",title:"Computer Vision",keywords:"Image Analysis, Scene Understanding, Biometrics, Deep Learning, Software Implementation, Hardware Implementation, Natural Images, Medical Images, Robotics, VR/AR",scope:"The scope of this topic is to disseminate the recent advances in the rapidly growing field of computer vision from both the theoretical and practical points of view. Novel computational algorithms for image analysis, scene understanding, biometrics, deep learning and their software or hardware implementations for natural and medical images, robotics, VR/AR, applications are some research directions relevant to this topic.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/24.jpg",hasOnlineFirst:!1,hasPublishedBooks:!0,annualVolume:11420,editor:{id:"294154",title:"Prof.",name:"George",middleName:null,surname:"Papakostas",slug:"george-papakostas",fullName:"George Papakostas",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002hYaGbQAK/Profile_Picture_1624519712088",biography:"George A. Papakostas has received a diploma in Electrical and Computer Engineering in 1999 and the M.Sc. and Ph.D. degrees in Electrical and Computer Engineering in 2002 and 2007, respectively, from the Democritus University of Thrace (DUTH), Greece. Dr. Papakostas serves as a Tenured Full Professor at the Department of Computer Science, International Hellenic University, Greece. Dr. Papakostas has 10 years of experience in large-scale systems design as a senior software engineer and technical manager, and 20 years of research experience in the field of Artificial Intelligence. Currently, he is the Head of the “Visual Computing” division of HUman-MAchines INteraction Laboratory (HUMAIN-Lab) and the Director of the MPhil program “Advanced Technologies in Informatics and Computers” hosted by the Department of Computer Science, International Hellenic University. He has (co)authored more than 150 publications in indexed journals, international conferences and book chapters, 1 book (in Greek), 3 edited books, and 5 journal special issues. His publications have more than 2100 citations with h-index 27 (GoogleScholar). His research interests include computer/machine vision, machine learning, pattern recognition, computational intelligence. \nDr. Papakostas served as a reviewer in numerous journals, as a program\ncommittee member in international conferences and he is a member of the IAENG, MIR Labs, EUCogIII, INSTICC and the Technical Chamber of Greece (TEE).",institutionString:null,institution:{name:"International Hellenic University",institutionURL:null,country:{name:"Greece"}}},editorTwo:null,editorThree:null,series:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403"},editorialBoard:[{id:"1177",title:"Prof.",name:"António",middleName:"J. R.",surname:"José Ribeiro Neves",slug:"antonio-jose-ribeiro-neves",fullName:"António José Ribeiro Neves",profilePictureURL:"https://mts.intechopen.com/storage/users/1177/images/system/1177.jpg",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"220565",title:"Dr.",name:"Jucheng",middleName:null,surname:"Yang",slug:"jucheng-yang",fullName:"Jucheng Yang",profilePictureURL:"https://mts.intechopen.com/storage/users/220565/images/5988_n.jpg",institutionString:null,institution:{name:"Tianjin University of Technology",institutionURL:null,country:{name:"China"}}},{id:"29299",title:"Prof.",name:"Serestina",middleName:null,surname:"Viriri",slug:"serestina-viriri",fullName:"Serestina Viriri",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYOalQAG/Profile_Picture_1620817405517",institutionString:null,institution:{name:"University of KwaZulu-Natal",institutionURL:null,country:{name:"South Africa"}}},{id:"315933",title:"Dr.",name:"Yalın",middleName:null,surname:"Baştanlar",slug:"yalin-bastanlar",fullName:"Yalın Baştanlar",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00002qpr7hQAA/Profile_Picture_1621430127547",institutionString:null,institution:{name:"Izmir Institute of Technology",institutionURL:null,country:{name:"Turkey"}}}]},onlineFirstChapters:{paginationCount:5,paginationItems:[{id:"82701",title:"Pathology of Streptococcal Infections",doi:"10.5772/intechopen.105814",signatures:"Yutaka Tsutsumi",slug:"pathology-of-streptococcal-infections",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Yutaka",surname:"Tsutsumi"}],book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"82634",title:"Bacterial Sexually Transmitted Disease",doi:"10.5772/intechopen.105747",signatures:"Lebeza Alemu Tenaw",slug:"bacterial-sexually-transmitted-disease",totalDownloads:12,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Bacterial Sexually Transmitted Infections - New Findings, Diagnosis, Treatment, and Prevention",coverURL:"https://cdn.intechopen.com/books/images_new/11569.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"82193",title:"Enterococcal Infections: Recent Nomenclature and emerging trends",doi:"10.5772/intechopen.104792",signatures:"Kavita Raja",slug:"enterococcal-infections-recent-nomenclature-and-emerging-trends",totalDownloads:14,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"81821",title:"Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination",doi:"10.5772/intechopen.104999",signatures:"Adnan Al-Lahham",slug:"pneumococcal-carriage-in-jordanian-children-and-the-importance-of-vaccination",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"80546",title:"Streptococcal Skin and Skin-Structure Infections",doi:"10.5772/intechopen.102894",signatures:"Alwyn Rapose",slug:"streptococcal-skin-and-skin-structure-infections",totalDownloads:77,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}}]},publishedBooks:{paginationCount:1,paginationItems:[{type:"book",id:"10652",title:"Information Extraction and Object Tracking in Digital Video",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10652.jpg",slug:"information-extraction-and-object-tracking-in-digital-video",publishedDate:"August 17th 2022",editedByType:"Edited by",bookSignature:"Antonio José Ribeiro Neves and Francisco Javier Gallegos-Funes",hash:"d13718b2d986d058d55cf91e69bf21c0",volumeInSeries:11,fullTitle:"Information Extraction and Object Tracking in Digital Video",editors:[{id:"1177",title:"Prof.",name:"António",middleName:"J. R.",surname:"José Ribeiro Neves",slug:"antonio-jose-ribeiro-neves",fullName:"António José Ribeiro Neves",profilePictureURL:"https://mts.intechopen.com/storage/users/1177/images/system/1177.jpg",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.png",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}},{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}}]},submityourwork:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:11,numberOfPublishedChapters:91,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:333,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:11,numberOfPublishedChapters:144,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:124,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:23,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:12,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],subseriesList:[{id:"3",title:"Bacterial Infectious Diseases",scope:"