\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"3257",leadTitle:null,fullTitle:"Current Issues and Future Direction in Kidney Transplantation",title:"Current Issues and Future Direction in Kidney Transplantation",subtitle:null,reviewType:"peer-reviewed",abstract:"The here presented book covers different areas of clinical and scientific interest, reaching from donor evaluation to newest methods in immunological diagnostics. But also aspects of daily care of transplant recipients can be found in the carefully selected chapters. Everything driven by the aim to improve the care for all of our transplanted patients.",isbn:null,printIsbn:"978-953-51-0985-3",pdfIsbn:"978-953-51-7089-1",doi:"10.5772/45909",price:139,priceEur:155,priceUsd:179,slug:"current-issues-and-future-direction-in-kidney-transplantation",numberOfPages:492,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"32aaeaf9eae59e0b53029c221285c846",bookSignature:"Thomas Rath",publishedDate:"February 13th 2013",coverURL:"https://cdn.intechopen.com/books/images_new/3257.jpg",numberOfDownloads:62352,numberOfWosCitations:27,numberOfCrossrefCitations:22,numberOfCrossrefCitationsByBook:1,numberOfDimensionsCitations:41,numberOfDimensionsCitationsByBook:1,hasAltmetrics:1,numberOfTotalCitations:90,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 11th 2012",dateEndSecondStepPublish:"May 2nd 2012",dateEndThirdStepPublish:"August 6th 2012",dateEndFourthStepPublish:"November 4th 2012",dateEndFifthStepPublish:"December 4th 2012",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"67436",title:"Dr.",name:"Thomas",middleName:null,surname:"Rath",slug:"thomas-rath",fullName:"Thomas Rath",profilePictureURL:"https://mts.intechopen.com/storage/users/67436/images/system/67436.jpg",biography:"Thomas Rath is a doctor of medicine and specialist in internal medicine, nephrology, hypertension, and infectious diseases. He lives in Kaiserslautern, a city of 100,000 inhabitants in the southwest part of Germany. After completing his studies at the University of Mainz, he became a resident at the Westpfalz-Klinikum in Kaiserslautern, a tertiary care hospital with 1300 hospital beds. There, he is Head of the Department of Nephrology and Transplantation Medicine and also responsible for the outpatient clinic for patients with infectious diseases. He is an active member of many national and international societies. During his scientific career he has published more than 25 papers in peer-reviewed journals and more than 150 abstracts and posters at national and international congresses. He gives lectures at the Technical University of Kaiserslautern on “artificial organ support.”",institutionString:"Westpfalz Klinikum",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"4",institution:{name:"Westpfalz Klinikum",institutionURL:null,country:{name:"Germany"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1163",title:"Nephrology",slug:"nephrology"}],chapters:[{id:"42862",title:"Medical Evaluation of the Adult Kidney Transplant Candidate",doi:"10.5772/54736",slug:"medical-evaluation-of-the-adult-kidney-transplant-candidate",totalDownloads:2643,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Phuong-Thu Pham, Son V. 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This process can be conceptualised as the ability to use what has been learned and to maintain this usage over time. To examine this transfer issue, a large scale study was conducted on a population undertaking a new national education programme to instruct health workers in treatments of anxiety and depression using psychological therapy. These cohorts of students from the new national education programme were followed up over a 3-year period to explore the process of transferring new learning in practice.
\nThe World Health Organisation (WHO) in 2013 estimated that mental health problems, particularly depression, will be among the greatest health challenges of this century [1]. Mental ill-health presents difficulties not only to the individual but to their entire social network (family, friends, etc.). Additionally, the economic impact, not only to the individual but also to the wider national economy, is significant [2, 3]. Within the United Kingdom, the total economic costs of mental health are estimated to be £25 billion per annum [4, 5].
\nPrior to a health policy initiative in this area, it was estimated that only 8% of people with a major depressive illness had seen a consultant psychiatrist and only 3% had seen a clinical psychologist [6]. The unaccounted people suffering with depression and anxiety were deemed to be receiving no form of evidence-based psychological therapy at all [2].
\nTo address the issues above, The Department of Health (DH) proposed by the Department of Health (DH) in 2008 to develop a service to educate and train a workforce to offer evidence-based psychological therapy interventions—the improving access to psychological therapy (IAPT) service. The IAPT service, from 2010 offered treatments, primarily cognitive behaviour therapy (CBT) which increased coping abilities, taught self-help approaches and promoted resilience for future mental health challenges. Referral to specialist services (if needed) could be completed simply, efficiently and effectively. Finally, IAPT sought to promote social inclusion and normal life patterns through access to work. This workforce expansion represented a major investment in education and service development. To achieve this, a national skills-based education programme was initiated [7].
\nThis implementation of a new workforce and national education and training programme merited deeper analysis. It is important that services develop an understanding of the implementation and embedding process for service improvement [8]. To achieve this, an integrative review of the literature was conducted with an emphasis placed on systematic reviews of the ‘transfer of training’. Based on this review and detailed analysis of major research reviews such as [9] along with many earlier authors [10–12], key components of transfer were identified such as, the personal characteristics of the trainees, the characteristics of the training programme and the characteristics of the work setting.
\nTo explore this, a series of interviews with practitioners, clinical supervisors, service managers and national policy managers were held. The aim was to obtain a richer and deeper understanding of the process of learning transfer from the national policy to daily practice.
\nResearch on learning transfer models have been primarily linear [10, 13]. This current design articulated a stronger emphasis on a complex systems analysis to understand the transfer process. The study design was a representation of a complex system as it met all relevant criteria:
\nA large number of elements are constantly interacting with each other.
Each part of the system is affected by others, with feedback being a key aspect of its operation.
Small changes in one part of the system have the potential to create large effects in others.
The system is difficult to define or boundary.
The system has a history which helps shape the current behaviour.
Elements in the system are not fully aware of the behaviour of other parts of the system and only react to what is known locally [14, 15].
The method adopted for this part of the study consisted of single hour long interviews with six IAPT therapists who were graduates of the education programme, three service managers (who were responsible for the day to day operation of the service), four national policy managers (who were instrumental in establishing the IAPT service for the Government of the day) and two clinical supervisors (who were responsible for supporting IAPT therapists to maintain and continually develop, their practice skills). Focus groups were held with thirty other IAPT practitioners, who had not attended the programme under review. Focus groups were used to triangulate data from other sources.
\nThe population consisted of 64 post-graduate students studying on the improving access to psychological therapy (IAPT) course delivered at a Higher Education Institution (HEI) approved by the national policy team. The course was a full time, skills based, CBT training course run over a period of a single year. The participants were individuals who had demonstrated sufficient skills and experience of psychological therapy to merit a place on the programme. The HEI which was delivering this IAPT curriculum was approached for permission to seek consent of the student group. On granting of this permission, the students were invited to take part via an email from the course leader prior to commencing the programme. Permission to approach the students was also sought and granted via the university, health service managers and local research and development ethics committees.
\nAn interview schedule was developed for this qualitative data element of the design. Interviews and focus groups were held with IAPT practitioners, including one focus group of the wider IAPT team from the same organisation (i.e. those IAPT practitioners who were not in the original trainee cohort) and one with IAPT practitioners from a separate English National Health Service (NHS) region in order to triangulate aspects of the data collected. All individual 1:1 interviews were transcribed verbatim and additional notes kept and developed at the earliest opportunity following the discussion. Focus group data were recorded and transcription notes taken from the recordings. The transcription process utilised the work of Kowal and O’Connell [16] and Roulston [17] in taking a pragmatic approach to transcription, with no detailed textual annotations included. This aim of simplicity was carefully considered and so recorded interviews were repeatedly listened to ensure the transcriptions retained not only the documented words but also the spirit of the conversation. Qualitative content analysis used the three stage method for data analysis [18]. This process involved: (i)
Conceptually, the data analysis approach reflected the examination of patterns in the data, seeking examples with a strong ‘fit’ with others. The examination of coherence and clustering data aimed to provide a plausible narrative of the data. The narrative could be jarring, but by recognising that dissonant perspectives expressed by participants could also generate important themes worthy of closer examination [20]. The relation between variables expressed as either consensus or dissensus was potential area for the examination of new understanding.
\nThe transcribed and recorded data were read and reviewed many times and annotated. A reflexive approach was adopted to form a picture of the experience of the respondents. As themes emerged from the data, via initial coding and recoding [19] and they were entered into an analysis table and reanalysed until separation of the key themes emerged and the data saturation was evident [21].
\nIn identifying themes, it was necessary to offer a clear articulation of the process of analysis since this supported clarity of approach and facilitates others to replicate the research process. Themes do not emerge within an epistemological vacuum; the researcher played an active role in the process of deciding what is important in the data. Being transparent about the process of thematic identification and promoting a reflexive account of the values and opinions of the researcher, enables other reviewers of the research to assess the completeness of the process.
\nThe research design accentuated the identification of ‘patterns’ within the transfer process, which are often the tacit but critical elements which play an important role in the complex interaction between organisational structures and process [22].
\nUnexpected findings or extreme results were prioritised for exploration as to whether the study was generating new insights into the transfer of learning. The process of theme development was based on a close reading and re-reading of the transcribed material and a reflexive approach to the research aim. Through this process, a number of themes emerged were considered to have a significant role in the transfer process. All interviews produced a wealth of material and many quotes were gathered which crystallised the emerging themes.
\nThe training programme for IAPT was based on a competency model as influenced by Roth and Pilling [23], although the concept of competency had yet to be adequately defined or measured [24]. Most often it was related to therapist self-reported increase in confidence and their belief in achieving treatment outcomes.
\nFor some interviewees, the training programme and subsequent practice exposure had helped them view their skills more critically. One interviewee, despite having a long history of working as a professional in mental health services identified how the programme had helped them develop a deeper understanding of their skills and deficits. They saw themselves developing new skills and being able to deliver them meaningfully in practice. The process of development was supported through critical evaluation of their skills through the use of video recording of their current competence and capability:
\nThe issue of competence and confidence was of paramount interest to clinical supervisors too:
\nA relationship existed in the psychological literature between competence, or the desire for competence, and ‘motivation’ [25]. Within the data an attribute that many responders identified was the need to exhibit motivation to work as a high intensity IAPT therapist.
\nRespondents considered the importance of developing and maintaining an IAPT identity for the workforce as critical in enabling them to remain within services and remain motivated to develop their practice further. Professional identity and the associated emphasis on personal motivation were critical issues within the transfer process. However, within such a complex clinical environment, significant challenges were identified.
\nSome practitioners identified solutions to the challenges they faced from the internal and external pressures that affected their work. Strongly linked to the concept of motivation and transfer, these practitioners seemed to develop a resistive stance to the accepted norms or a sense of compromise between what they thought they were as therapists and what they were expected to do.
\nThe role of identity as a supportive process to aid a sense of certainty of purpose and to facilitate the coherent and consistent application of key agreed skills and competences was considered important. The national policy leads, made clear statements about, IAPT being an opportunity to develop a new workforce and to protect its emerging identity.
\nThe transfer of learning for an (emerging) profession might be predicated on a consistent and coherent application of a body of knowledge. This would seem to be a challenge for the IAPT programme of which national policy leads were well aware.
\nThe data on identity raised a number of examples where the emerging identity and application/transfer of new skills was threatened by tensions. These challenges were faced by practitioners, policy managers, supervisors and service managers and formed a significant theme in all the analysis. The external wider clinical environment was seen as the principal reason for challenges in transfer behaviour. Clinical practice was viewed as high pressure, time limited and replete with many quotes relating to healthcare provision as challenging.
\n‘
The external pressures were also evident for policy managers, as the theme of tension was evident in their responses. A number of respondents identified that policy implementation was highly challenging as the ‘whole system’ worked against an evidence-based application of practice:
\nThere were many examples of where respondents identified the shortfall in their initial implementation aims. While on the whole it was clear that many aspects of the policy had been achieved, it had been done so at some cost to compromise and relinquishing control:
\nThe external (political) environment was a feature of every interview. There did appear to be a consensus that while policy formulation was challenging but achievable, the implementation proved a challenge given a lack of infrastructure to support the process:
\nThis was not to say that IAPT practice was not without emotional costs with a number of therapists identifying a sense of exhaustion an often referenced issue within the interview data.
\nThe time to consider the integration of skills to practice; the process of transfer was not a significant feature of the interview data with policy leads. Yet for other respondents, the focus on targets for client contact and recovery was seen as the main issue about service delivery. It was considered to be the main agenda item at the expense of quality and practitioner development. These targets were the subject of local negotiation and funding arrangements with commissioners. As a consequence, the contact and recovery targets formed an important strand of the tension expressed by managers and IAPT therapists.
\nThe provision of supervision was another recurring theme in the focus groups and interviews with IAPT practitioners. Supervision was viewed as a process aimed at providing the supervisee with the opportunity to engage in some form of learning or reflection on practice. In this mode, supervision could be viewed as having the principal role in supporting the transfer process within the work-setting.
\nSome respondents identified supervision as a management tool used to support service demands rather than individual learning and development:
\nThe views of the policy leads varied too on the process of supervision and support:
\nIn interview and focus group, a number of IAPT therapists stated that originally, clinical supervision was given greater prominence in their working plan, but as workload pressures had increased, supervision had been reduced:
\nThe transfer of learning acquired or confirmed in educational settings and transferring them to the work setting was at the heart of this study. The ‘real world’ application had links to the themes of ‘tension and external environment’ and ‘supervision and support’. There was a clear distinction drawn by many practitioners (but to a much lesser extent acknowledged in the interviews with policy leads) between the world of education and the ‘real world’ of practice. Respondents repeatedly used the phrase ‘real world’ to describe practice how it
This distinction was noted by some policy leads but the dissonance between what was considered good practice and what was evident in the ‘real world’ was not viewed as a unimportant theory-policy gap. One of the respondents spoke candidly about the challenges for policy leads:
\nThe issue of transfer from training to the ‘real world’ or the sphere of influence was an often cited aspect of the interview dialogue. The simple linear development of services and training was not reflected in practice. This simplicity of implementation was viewed as something alien to mental health services, something services had historically failed to develop.
\nTherapeutic drift was explicitly and implicitly stated in the majority of interviews. It was conceptualised by IAPT practitioners as the moving away from the set approach that was taught on the programme. The concern was whether therapeutic drift was a relaxation of skills or an example of the development of higher order skills.
\nAll practitioners noted that the transfer of learning had progressed beyond the expectations of training and concern was expressed whether they were still holding a fidelity to their initial training or whether they had drifted away:
\nThe reasons for this were varied, but many participants identified the challenges of the external environment as a principal influencing factor.
\nThe issue of drift was also identified by the supervisors, who were clear on the need for supervision to protect the skills that the IAPT therapists had and continued to develop:
\nThe study produced an extensive amount of data which required careful analysis in order to explore the emergent themes. The complex frame used to understand the inter-relationships between the various variables that were used to synthesise the data; to construct a narrative that provided a structured analysis of the evidence on key factors that inhibited or facilitated educational transfer in primary care mental health services.
\nThe results of this study identified a number of inter-connected themes. IAPT therapists, supervisors and managers articulated a picture of psychological therapy in primary care, which was challenging and susceptible to changes in policy direction and practice imperatives. The core target client group; those people with anxiety and/or depression had been integrated into treatment groups with people with additional and sometimes multiple social and health needs.
\nData illustrated an emphasis on the desire of all respondents in clinical roles to offer effective psychological treatment and so motivation was a prominent theme. The change model of West and Brown [26] towards behaviour (such as transfer behaviour) identified the need to have the capability or skills to change; the opportunity to change behaviour and the motivation to do so to direct behaviour. According to reference [26], the maintenance of a strong and resilient identity was critical for behaviour (such as transfer behaviour) to be maintained. There was evidence that all elements of the capability, opportunity and motivation process were utilised by IAPT therapists. A number of therapists doubted whether they were faithful to the CBT approach and whether they were provided with as many opportunities to fully practice their skills. The results indicted a link to the concept of therapeutic drift, which again was a sentiment expressed by a number of therapists. Both therapists and supervisors noted concerns that the education programme for IAPT emphasised treatment interventions for anxiety and depression derived from clinical research trials. Many responded with an acknowledgement they were practising a hybrid approach, instilling a sense of uncertainty of either drifting from CBT orthodoxy or developing deeper CBT skills based on the core principles gained from the original training programme. Therapists and supervisors were engaged in a trade-off between practicing with fidelity to the CBT model or developing a deeper sense of confidence and capability in responding to a complex client group. This fidelity drift/confidence dissonance was set within a clearly expressed awareness of the political, social and economic forces at play.
\nThe frequent response from interviewees was that training and its transfer had to be adapted to the ‘real world’ setting. The education programme within the education institution was viewed as a place to learn and practice core skills in a safe and ‘unreal’ setting. Exposure to actual practice of IAPT was seen very differently, where concerns of therapist isolation and autonomous decision making were stressors.
\nThe work of Burke and Hutchins [9] was used to guide the research around topics with little or no empirical evidence for their role in the transfer of learning. In this study, clinical supervision emerged as a meta-theme that seemed to unite all others in supporting educational transfer in IAPT. The importance of supervision was mentioned in every interview and it was possible to deduce a role of structured clinical supervision playing an important role in responding to the challenges and opportunities identified in the qualitative and quantitative data.
\nThis study provided an insight into the complexity associated with the process of learning transfer in the English NHS. Healthcare is a dynamic and politicised agenda with many competing demands impinging on the day to day work of nurses and other practitioners. It is important that education developers, teachers and service managers have a deeper appreciation of the complex and challenging practice environment that students are working when considering the transfer of learning.
\nGeoscience is a knowledge-intensive discipline. It has not only domain-specific terminology but also a deep intersection with mathematics, chemistry, and physics, which form a series of distinctive subdisciplines, such as geophysics, geomathematics, geochemistry, paleobiology, and more [1, 2, 3]. Thanks to the rapid development of detection techniques in the micro- and macroscales in the past decades, both the volume and quality of geoscience data have been improved greatly. A feature of detection-based research is using the extrapolation method to explore the Earth. For instance, geochemists use local geochemical data to invert the process of Earth evolution and geodynamics [4, 5]. The diverse big data and improved computer software and hardware enable an opportunity to understand the evolution of Earth system using simulation and data mining methods [6].
Many geoscience research outputs are recorded in the form of literature, making text data an integral part of geoscience big data [7]. Important information and knowledge are recorded in unstructured textural form and thus hidden in the geological literature. Nowadays, the advanced Web technologies promote the publication process of academical literature and accelerate literature exchange globally. Researchers can easily assemble publications of focused topics. In this regard, geological literature has become a big “mineral resource” for data mining and provides tremendous opportunities for new knowledge discovery. In recent years, the open data initiative has promoted government agencies, scientific organizations, and academic publishers to provide literature archives for nonprofit reuse; some are even open and free. For instance, the US Geological Survey (USGS) and China Geological Survey (CGS) have published outputs of geological survey investigation online [8, 9]. Elsevier and Springer have provided application programming interfaces (API) for developer and scientists to access metadata, full text, and conduct text mining [10, 11]. We anticipate that more geological literature will be made available by publishers, government agencies, research organizations, and individual scientists in the coming years.
In a recent review article [12], Gil and other scholars proposed a research agenda of intelligent systems that will result in fundamental new capabilities for understanding the Earth system. Automated information extraction and integration from published literature is listed as a key research direction in the agenda. Domain-specific text mining can be regarded as a topic in interdisciplinary fields, such as geoinformatics, ecoinformatics, and bioinformatics. Conventionally, text mining is a research topic in computer science. The new development in interpreted programming language and the wide-spreading open-source packages and libraries enable scholars in various disciplines to quickly learn the latest algorithms and apply them to their domain-specific researches. There are many widely used open and free libraries in text mining, such as TensorFlow [13], DeepDive [14], Caffe [15], CNTK [16], and MXnet [17]. Even if a researcher has only the basic skills in programming, he or she will be able to make a deep research using these libraries.
Text mining contains the following major steps: data collection and preprocessing, identification of entities and their links, and knowledge representation. Data collection can take place in many forms. For example, one can require permission to get data from a database or publisher and can also retrieve data form the Web by a data extractor. The obtained data from different sources may be recoded in diverse formats, such as text files and scanned images. It is necessary to transform the data into an organized, computer-readable format. For instance, we can use the optical character recognition (OCR) to identify characters and words from the scanned images of a book or paper. After the preprocessing, the next step is to analyze the information and meaning of the text data. In the early stage, many researchers have tried to use automatic text summarization to extract a concise and informative abstract that covers the key information of a text document [18, 19, 20]. Nevertheless, due to the limitation of poor readability, automatic text summarization has yet to achieve satisfactory results.
Knowledge graphs, as proposed by Google, are semantic networks with directed graph structure, which have provided new ideas to extract and represent the text information. The words representing the major entities and relationships carry the key information in a document. Therefore, a text document can be represented by a knowledge graph to show a list of entities and their relationships. The structured knowledge graph is a specific data base and can be further analyzed and visualized by graph methods. Every entity is regarded as a graph node, and the relationship between two nodes is represented as an edge. The graph visualizes the nodes and edges to represent the implicit information network of a document. In recent years, many open knowledge graphs have been constructed based on text information, such as Google knowledge vault [21], DBpedia [22], Freebase [23], YAGO [24], Wikidata [25], OpenIE [26], and NELL [27]. These knowledge graphs devote to acquire entities and their links for various topics during the construction. In contrast, some domain-specific knowledge graphs only focus on one or a few topics. For instance, the MusicBrainz [28], UniProtKB [29], and GeoName [30] are knowledge graphs in the music, biology, and geography fields, respectively. The recent development of NLP and semantic technologies also provide new methods and tools for building knowledge graphs [14, 31, 32].
In this chapter, we will review the development of text mining in the domain of geoscience in recent years and present results of a few case studies. Comparing with other disciplines, the domain of geoscience still has limited applications of NLP and text mining. We hope the presented work will be of interested to the text mining community, and we anticipate more innovative text mining applications will appear in geoscience and other disciplines in the near future.
Text data are usually consisted of sentences written by authors with personal understandings and opinions. Compared to metadata, text data are characterized by ambiguity, polysemy, and irregular input in the natural language. It is difficult for computers to read and understand. It is necessary to segment a piece of text into semantic word sequences for further computer processing. English and other Latin languages have relatively simple morphology, especially inflectional morphology, and are segmented by spaces between words naturally. For those languages, it is often possible to ignore the word segmentation task entirely. In contrast, there is no space between words in a few other languages, such as Chinese. It is difficult for a computer to identify the boundary of a meaningful word or phrase in Chinese [33, 34]. The methods of Chinese word segmentation were classified into dictionary-based, statistically based, and hybrid approaches [33]. The statistically based methods include machine learning and deep learning methods, such as hidden Markov model (HMM), maximum entropy Markov model (MEMM), conditional random fields (CRF), and long short-term memory (LSTM).
From another perspective, the methods of word segmentation can be divided into generic and specific domain methods according the usage scenarios. In the generic domain, because of the shortcomings of word segmentation rules, some new words, especially the professional terms, will be regarded as out-of-vocabulary and cannot be identified correctly. Geology, as a knowledge-intensive discipline, has a systematic domain-specific terminology. Most of geologic terms are not familiar with the public. Geological literature including the geological terms has their unique characteristics. For instance, the geological literature is always organized according to some fixed format and contains lots of professional geologic terms that only people with a background knowledge can read and understand. The geological literature is dominated by descriptive sentences and has little ambiguity in information expression. In geological literature written in Chinese, it is also featured by mixed writing of Chinese and English terms as well as compound terms consisted of multiple geological terms [2, 7]. The text data in the natural language are sequence data; the word usage and combination are only influenced by the context. Based on the characteristics of text data, machine learning method (e.g., CRF) and deep learning method of neural network (e.g., neural network (CNN), LSTM) have been introduced to segment geological literature in Chinese in recent 2 years with successful results [7, 34, 35, 36].
For a random vector (e.g., in NLP), the joint probability is a high-dimensional distribution, which oversteps the processing power of an ordinary computer and is difficult to monitor during data processing. To reduce the data size, the high-dimensional distribution is divided into a series of production of conditional probability based on the independence hypothesis [37]. The probabilistic graphical model is a graph to describe independence relationship between multivariate in a high-dimensional probabilistic model, thus to reduce computer load. The probabilistic graphical model includes both directed and undirected models. The directed graphical model indicates there is a causation relationship between the variables, such as Bayesian networks. The variables in undirected graphical model have dependency with each other, such as Markov networks and CRF, which is different from the causation relationships.
CRF model is a discriminative graph model, while HMM is a generative graph model. The role of CRF model is to create the discriminant boundaries similar to the support vector machine model, which has a wide usage in the fields of NLP and bioinformatics. Compared with HMM and the maximum entropy model (MEM), the CRF model improves the accuracy and addresses the drawback of label bias [38, 39]. Text data are unstructured sequence data. The structuralization of geological text is a process of word segmentation or named entity recognition (NER), which divides the geological text into a series of semantic words. For natural language, the text is only influenced by the context, which is consistent with the assumption condition of the CRF model. The assumption condition is that multivariable obeys the Markov property. In other word, the label of part of speech at
where
A chain-structured CRF graph [
According the factorization of joint probability distribution of undirected graph, the CRF model can be written as
In which
In CRF-based word segmentation, Wang et al. [7] designed a two-step workflow to segment geological literature in Chinese. First, a hybrid corpus was created using dictionary matching and manual label methods on the basis of geological literature in CNKI, geology dictionary, TCCGMR (the terminologies and classification codes of geology and mineral resources), and a generic corpus of Peking University. Second, the segmentation rules were trained to build geological word segmentation model by the hybrid corpus, and then the trained model containing word segmentation rules was used to segment geological literature in Chinese. The workflow is shown in Figure 2.
Workflow of CRF-based word segmentation for geological literature in Chinese.
In that study, a geology dictionary of 11,000 geological terms, the TCCGMR of 80,000 geological terms, and the generic corpus of Peking University were used to build the hybrid corpus. By this way, geological knowledge was introduced into the corpus to train the rules of word segmentation of geological literature. It is the most notable feature compared with other Chinese word segmentation machine. The three parameters of precision, recall, and F-scores were used to evaluate the performance of CRF-based word segmentation in that work. The result was showed in Figure 3. The hybrid corpus combining a generic corpus and a geological corpus has a better performance than either the generic corpus or the geological corpus alone. The precision of the hybrid training reaches 94.14%, which is 7.84% and 0.52% higher than that of CRF-PKU and CRF-GEO, respectively. The recall of hybrid corpus reaches 91.40%, which is 9.30% and 0.41% higher than that of CRF-PKU and CRF-GEO, respectively. The F-score of the hybrid corpus reaches 92.75%, which is 8.60% and 0.46% higher than that of CRF-PKU and CRF-GEO, respectively.
Performances of the CRF model in different corpus. CRF-PKU, generic corpus of Peking University; CRF-GEO, geological corpus; CRF-GEO + PKU, the hybrid corpus combining generic and geological corpora.
The text data are consisted of a series of sequential words or characters, which can be regarded as a special data of time series and can be processed by the methods used in the time series analysis. Words or characters in text data are not completely independent but are connected to and influenced by the adjacent words or characters. In the model of neural network, it contains three basic compositions: input layer, hidden layer, and output layer. The layers of ordinary neural networks are linked with each other by weights. The nodes in a same layer are independent and have no link with each other. If the ordinary neural network methods are used to process text data, the semantic information of context will be missing. Recurrent neural network (RNN) has a short memory by nodes connecting in the hidden layer, which can receive information from self-cell and other cells. RNN has been used in the fields of NLP and automatic speech recognition [41, 42]. RNN model has the drawback of vanishing gradient problem, which means RNN model only obtains the information that is limited in the adjacent node position [43]. To address this challenge, the LSTM model designed input gate, output gate, and a forget gate to obtain information of far nodes and regulate the information flow between the cells [44] (Figure 4).
in which
The cell of LSTM [
Qiu et al. [36] proposed a geological literature segmenter based on the Bi-LSTM model. The segmenter was carried out by the following stages (more details can be seen in the reference article):
Corpus construction: The corpus from domain-generic and domain-specific texts is collected and constructed.
Words grouped: Each word is grouped based on frequency and a ranking algorithm.
Random extraction and combination: Each group of words in the previous step is extracted and joined together randomly.
Training: With the previous processing, sentences are formed via combination based on deep learning.
Testing and output: The resulting segmentation is post-processed and output.
In this research work, the significant highlight is that the training corpus is random. The segmentation rule was learned from the words and their corresponding sequences of the training corpus. The training corpus did not have any manual label information. The precision, recall, and F-scores reach 86.1%, 87.1%, and 86.6%, respectively. Compared with Wang et al. [7], the performance of CRF-based method is better than the Bi-LSTM-based segmenter based on the performance reported in their papers. But the Bi-LSTM-based method has a strong ability of identifying new words. The rate of out-of-vocabulary word identification reached 71.1%.
The nodes of content word and their links are the carrier of literature information and knowledge. In a large open knowledge graph, the key information was stored in in a triple format. Moreover, the bigram is also widely used in the text information representation. Wang et al. [7] used the bigram graph to represent the single geological literature.
The visualization was built based on the “from,” “to,” and “weight” variables. The variables of “from” and “to” indicate the sequence of content words in the content word corpus. In the content-word pairs, the former content word is defined as “from” variable, and the latter is defined as “to” variable. Their weights were defined by the co-occurrence frequency of content-word pairs. The bigram graph was used to visualize the nodes of content words and their links.
In geological exploration, the anomaly information of geology, geochemical exploration, geophysical exploration, and remote sensing is important clues for mineral prospecting [46]. To state different anomaly information, literatures of geological exploration will have significant features in the term of word frequency. Figure 5 shows the main information hidden in a single literature of geophysical exploration. In this visualization, geological terms (e.g.,
Bigram graph of content words in the whole literature represents the key information in the geological report (n > 10).
Geology research not only reveals the earth evolution and promotes our understanding of the Earth but also has a close relationship with the human society. One of the important roles of applied geology is to discover mineral deposits and provide raw material for economic construction and development. In the long geological history, mineral deposits were formed with large-scale geological events and were buried in the depth of Earth crust. If the mineral deposits were not broken down under the erosion of weathering after mineralization, there are ways to discover them. In the earlier days, geologists discovered mineral deposits by identifying the rock outcrops associated with mineralization. Then, along with many technological developments, the geochemical exploration, geophysical exploration, and remote sensing were also used to improve the result of mineral prospecting and mineral exploration. In recent years, GIS-based and three-dimensional mineral prospect mapping has been used in mineral exploration. Through those technologies, multisource anomalies, such as geochemical anomalies, geophysical anomalies, geological anomalies, and remote sensing anomalies, can be determined.
The anomaly information is usually derived from structured numeric data. The structured numeric data are only one part of geological big data. The majority of geological big data are unstructured, such as text and image. Previous mineral exploration mainly depends on derived information from the structured numeric data. Some important information related to the mineral prospecting and exploration is hidden in the unstructured text, such as host rock, alteration types, geological setting, ore-controlled factors, geochemical and geophysical anomaly patterns, and location. The favorable information extraction and identification from geological literature are a big challenge for conventional research methods. The NLP-based text mining provides a chance to address this challenge.
Li et al. [35] used the CNN method to classify geological text data into four categories (geology, geophysics, geochemistry, and remote sensing) on three scales (word, sentence, and paragraph). Their work extended the work on Chinese word segmentation and text preprocessing to the domain of mineral exploration. These four categories represent four types of mineral exploration information. Compared with word and paragraph scales, the sentence scale has the best performance. In their work, the
The microfossil at 4280 million years old found in Quebec, Canada, may be the oldest fossil as so far [47]. In the Earth’s history, biological evolution has a close corresponding with the geological evolution. The existence of biology depends on specific physical and chemical conditions, such as oxygen content and temperature. In other words, different biotypes and biocenoses indicate the conditions of different earth environments. The fossils were formed along with the sedimentary environment and are the footprint left by the biosphere. Each fossil records some biological information, such as biological morphology and living environment. Paleontologists always study the fossils to explore the earth environment evolution. A single fossil cannot indicate biological and geological evolution. The conclusions of such evolution are based on a series of comparative studies of fossils in different geological times and settings.
The Paleobiology Database (PBDB; http://paleobiodb.org) contains systematic and detailed fossil information, which make it a necessary infrastructure for fossil comparative researches. The PBDB is one of the most successful fossil databases, which was founded nearly two decades ago. Now it has become an open and active community for different research agendas. In the initial stage, the fossil records in the PBDB were from original fieldworks and extracted from published literature manually. As the rapid development of digital publication, the manual data entry for fossil information became tedious and less efficient and was not able to deal with the massive amounts of new and legacy publications. To address this challenge, PaleoDeepDive [46], a machine reading and learning system, was developed to extract fossil information from literature. This system uses the factor graph and NLP technologies to identify fossil entities and their semantic relationships. The extracted results were stored in the form of triples inside a knowledge base. Compared with the manual fossil data entry, the output of PaleoDeepDive has an obvious advantage in terms of quantity. Moreover, the change trend (e.g., taxonomic diversity and genus-level turnover) has a high corresponding relationship with the manual data entry [48]. The extracted fossil records have been used to update the PBDB. Now, the PBDB is not just a paleobiology database, it also provides WebGIS-based interface for fossil information retrieval and query. It also provides R library, API, and a mobile APP for researchers and the general public to use. Based on the PDBD, a series of high-quality research papers have been published to improve our understanding about the Earth. For instance, Peters et al. [49] analyzed the rise and fall of stromatolites in North America and divided the marine environment into three phases based the change of stromatolites.
The application of GeoDeepDive is still ongoing. Macrostrat (https://macrostrat.org/), a collaborative platform for geological data exploration and integration, was constructed based on the results that GeoDeepDive extracted from massive amounts of scientific literature. By April 2018, Macrostrat has contained 33,903 properties of geological units distributed across 1474 regions in North and South America, the Caribbean, New Zealand, and the deep sea, more than 180,000 geochemical and outcrop-derived measurements, all the fossil records in PBDB, and more than 2.3 million bedrock geologic map units from over 200 map sources [50].
In this chapter, we reviewed the latest developments of NLP techniques in the domain of geoscience to accelerate knowledge discovery from geological literature and deepen our understanding about the Earth. From the review, it was concluded that the researches of text mining in geoscience are still in the early stage. Most current researches focus on the literature structuralization and simple information extraction at a single document scale. The information integration and knowledge discovery from the big data of geological literature require further work and will lead to a lot of innovative research topics and applications.
The authors thank Prof. Abdelkrim El Mouatasim and Dr. Kristina Kardum for their organization for this book and their assistance. This work was supported by the National Key R&D Program of China (2017YFC0601500, 2017YFC0601504) and Fundamental Research Funds for the Central Universities, China University of Geosciences (Wuhan) (No. 162301182382).
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Nikiforov and Christophe Leys",authors:[{id:"49112",title:"Prof.",name:"Christophe",middleName:null,surname:"Leys",slug:"christophe-leys",fullName:"Christophe Leys"},{id:"176861",title:"Dr.",name:"Anton",middleName:null,surname:"Nikiforov",slug:"anton-nikiforov",fullName:"Anton Nikiforov"},{id:"176862",title:"Mr.",name:"Patrick",middleName:null,surname:"Vanraes",slug:"patrick-vanraes",fullName:"Patrick Vanraes"}]}],mostDownloadedChaptersLast30Days:[{id:"49562",title:"Laser-Induced Plasma and its Applications",slug:"laser-induced-plasma-and-its-applications",totalDownloads:4805,totalCrossrefCites:12,totalDimensionsCites:26,abstract:"The laser irradiation have shown a range of applications from fabricating, melting, and evaporating nanoparticles to changing their shape, structure, size, and size distribution. Laser induced plasma has used for different diagnostic and technological applications as detection, thin film deposition, and elemental identification. The possible interferences of atomic or molecular species are used to specify organic, inorganic or biological materials which allows critical applications in defense (landmines, explosive, forensic (trace of explosive or organic materials), public health (toxic substances pharmaceutical products), or environment (organic wastes). Laser induced plasma for organic material potentially provide fast sensor systems for explosive trace and pathogen biological agent detection and analysis. The laser ablation process starts with electronic energy absorption (~fs) and ends at particle recondensation (~ms). Then, the ablation process can be governed by thermal, non-thermal processes or a combination of both. There are several types of models, i.e., thermal, mechanical, photophysical, photochemical and defect models, which describe the ablation process by one dominant mechanism only. Plasma ignition process includes bond breaking and plasma shielding during the laser pulse. Bond breaking mechanisms influence the quantity and form of energy (kinetic, ionization and excitation) that atoms and ions can acquire. Plasma expansion depends on the initial mass and energy in the plume. The process is governed by initial plasma properties (electron density, temperature, velocity) after the laser pulse and the expansion medium. During first microsecond after the laser pulse, plume expansion is adiabatic afterwards line radiation becomes the dominant mechanism of energy loss.",book:{id:"5093",slug:"plasma-science-and-technology-progress-in-physical-states-and-chemical-reactions",title:"Plasma Science and Technology",fullTitle:"Plasma Science and Technology - Progress in Physical States and Chemical Reactions"},signatures:"Kashif Chaudhary, Syed Zuhaib Haider Rizvi and Jalil Ali",authors:[{id:"176684",title:"Dr.",name:"Kashif Tufail",middleName:null,surname:"Chaudhary",slug:"kashif-tufail-chaudhary",fullName:"Kashif Tufail Chaudhary"},{id:"176867",title:"Dr.",name:"Syed Zuhaib",middleName:null,surname:"Haider Rizivi",slug:"syed-zuhaib-haider-rizivi",fullName:"Syed Zuhaib Haider Rizivi"},{id:"176868",title:"Prof.",name:"Jalil",middleName:null,surname:"Ali",slug:"jalil-ali",fullName:"Jalil Ali"}]},{id:"52164",title:"An Overview on Quantum Cascade Lasers: Origins and Development",slug:"an-overview-on-quantum-cascade-lasers-origins-and-development",totalDownloads:3255,totalCrossrefCites:2,totalDimensionsCites:11,abstract:"This chapter presents an introductory review on quantum cascade lasers (QCLs). An overview is prefaced, including a brief description of their beginnings and operating basics. Materials used, as well as growth methods, are also described. The possibility of developing GaN-based QCLs is also shown. Summarizing, the applications of these structures cover a broad range, including spectroscopy, free-space communication, as well as applications to near-space radar and chemical/biological detection. Furthermore, a number of state-of-the-art applications are described in different fields, and finally a brief assessment of the possibilities of volume production and the overall state of the art in QCLs research are elaborated.",book:{id:"5389",slug:"quantum-cascade-lasers",title:"Quantum Cascade Lasers",fullTitle:"Quantum Cascade Lasers"},signatures:"Raúl Pecharromán-Gallego",authors:[{id:"188866",title:"Dr.",name:"Raúl",middleName:null,surname:"Pecharromán-Gallego",slug:"raul-pecharroman-gallego",fullName:"Raúl Pecharromán-Gallego"}]},{id:"49526",title:"Focused Ion Beams (FIB) — Novel Methodologies and Recent Applications for Multidisciplinary Sciences",slug:"focused-ion-beams-fib-novel-methodologies-and-recent-applications-for-multidisciplinary-sciences",totalDownloads:4325,totalCrossrefCites:5,totalDimensionsCites:11,abstract:"Considered as the newest field of electron microscopy, focused ion beam (FIB) technologies are used in many fields of science for site-specific analysis, imaging, milling, deposition, micromachining, and manipulation. Dual-beam platforms, combining a high-resolution scanning electron microscope (HR-SEM) and an FIB column, additionally equipped with precursor-based gas injection systems (GIS), micromanipulators, and chemical analysis tools (such as energy-dispersive spectra (EDS) or wavelength-dispersive spectra (WDS)), serve as multifunctional tools for direct lithography in terms of nano-machining and nano-prototyping, while advanced specimen preparation for transmission electron microscopy (TEM) can practically be carried out with ultrahigh precision. Especially, when hard materials and material systems with hard substrates are concerned, FIB is the only technique for site-specific micro- and nanostructuring. Moreover, FIB sectioning and sampling techniques are frequently used for revealing the structural and morphological distribution of material systems with three-dimensional (3D) network at micro-/nanoscale.This book chapter includes many examples on conventional and novel processes of FIB technologies, ranging from analysis of semiconductors to electron tomography-based imaging of hard materials such as nanoporous ceramics and composites. In addition, recent studies concerning the active use of dual-beam platforms are mentioned",book:{id:"5075",slug:"modern-electron-microscopy-in-physical-and-life-sciences",title:"Modern Electron Microscopy in Physical and Life Sciences",fullTitle:"Modern Electron Microscopy in Physical and Life Sciences"},signatures:"Meltem Sezen",authors:[{id:"176338",title:"Associate Prof.",name:"Meltem",middleName:null,surname:"Sezen",slug:"meltem-sezen",fullName:"Meltem Sezen"}]},{id:"50866",title:"Effects of Different Laser Pulse Regimes (Nanosecond, Picosecond and Femtosecond) on the Ablation of Materials for Production of Nanoparticles in Liquid Solution",slug:"effects-of-different-laser-pulse-regimes-nanosecond-picosecond-and-femtosecond-on-the-ablation-of-ma",totalDownloads:6112,totalCrossrefCites:11,totalDimensionsCites:36,abstract:"Ultra-short laser pulse interaction with materials has received much attention from researchers in micro- and nanomachining, especially for the generation of nanoparticles in liquid environments, because of the straightforward method and direct application for organic solvents. In addition, the colloidal nanoparticles produced by laser ablation have very high purity—they are free from surfactants and reaction products or by-products. In this chapter, nanosecond, picosecond and femtosecond laser pulse durations are compared in laser material processing. Due to the unique properties of the short and ultra-short laser pulse durations in material processing, they are more apparent in the production of precision material processing and generation of nanoparticles in liquid environments.",book:{id:"5236",slug:"high-energy-and-short-pulse-lasers",title:"High Energy and Short Pulse Lasers",fullTitle:"High Energy and Short Pulse Lasers"},signatures:"Abubaker Hassan Hamad",authors:[{id:"183494",title:"Dr.",name:"Abubaker",middleName:"Hassan",surname:"Hamad",slug:"abubaker-hamad",fullName:"Abubaker Hamad"}]},{id:"49537",title:"Electron Diffraction",slug:"electron-diffraction",totalDownloads:10155,totalCrossrefCites:11,totalDimensionsCites:33,abstract:"Electron microscopes are usually supplied with equipment for obtaining diffraction patterns and micrographs from the same area of a specimen and the best results are attained if the complete use is to be made of these combined facilities. Electron diffraction patterns are used to obtain quantitative data including phase identification, orientation relationship and crystal defects in materials, etc. At first, a general introduction including a geometrical and quantitative approach to electron diffraction from a crystalline specimen, the reciprocal lattice and electron diffraction in the electron microscope are presented. The scattering process by an individual atom as well as a crystal, the Bragg law, Laue conditions and structure factor are also discussed. Types of diffraction patterns such as ring pattern, spot pattern and Kikuchi pattern, and general and unique indexing diffraction patterns are explained. The procedure for indexing simple, complicated and imperfect patterns as well as Kikuchi lines and a combination of Kikuchi lines and spots is outlined. The known and unknown materials are identified by indexing patterns. Practical comparisons between various methods of analysing diffraction patterns are also described. The basic diffraction patterns and the fine structure in the patterns including specimen tilting experiments, orientation relationship determination, phase identification, twinning, second phases, crystallographic information, dislocation, preferred orientation and texture, extra spots and streaks are described in detail. Finally, electron diffraction patterns of new materials are investigated.",book:{id:"5075",slug:"modern-electron-microscopy-in-physical-and-life-sciences",title:"Modern Electron Microscopy in Physical and Life Sciences",fullTitle:"Modern Electron Microscopy in Physical and Life Sciences"},signatures:"Mohsen Asadi Asadabad and Mohammad Jafari Eskandari",authors:[{id:"176352",title:"Dr.",name:"Mohsen",middleName:null,surname:"Asadi Asadabad",slug:"mohsen-asadi-asadabad",fullName:"Mohsen Asadi Asadabad"},{id:"177600",title:"Dr.",name:"Mohammad",middleName:null,surname:"Jafari Eskandari",slug:"mohammad-jafari-eskandari",fullName:"Mohammad Jafari Eskandari"}]}],onlineFirstChaptersFilter:{topicId:"20",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"83061",title:"Dipole Solitons in a Nonlocal Nonlinear Medium with Self-Focusing and Self-Defocusing Quintic Nonlinear Responses",slug:"dipole-solitons-in-a-nonlocal-nonlinear-medium-with-self-focusing-and-self-defocusing-quintic-nonlin",totalDownloads:0,totalDimensionsCites:0,doi:"10.5772/intechopen.106207",abstract:"Stability dynamics of dipole solitons have been numerically investigated in a nonlocal nonlinear medium with self-focusing and self-defocusing quintic nonlinearity by the squared-operator method. It has been demonstrated that solitons can stay nonlinearly stable for a wide range of each parameter, and two nonlinearly stable regions have been found for dipole solitons in the gap domain. Moreover, it has been observed that instability of dipole solitons can be improved or suppressed by modification of the potential depth and strong anisotropy coefficient.",book:{id:"10958",title:"Vortex Dynamics - From Physical to Mathematical Aspects",coverURL:"https://cdn.intechopen.com/books/images_new/10958.jpg"},signatures:"Mahmut Bağcı, Melis Turgut, Nalan Antar and İlkay Bakırtaş"},{id:"82984",title:"Feedback Linearization Control of Interleaved Boost Converter Fed by PV Array",slug:"feedback-linearization-control-of-interleaved-boost-converter-fed-by-pv-array",totalDownloads:0,totalDimensionsCites:0,doi:"10.5772/intechopen.106355",abstract:"One of the powerful methods of nonlinear control is the feedback linearization technique. This technique consists of input state and input-output linearization methods. In this chapter, the feedback linearization technique, including input state and input-output linearization methods, is described. Then, input-output linearization method is used for output voltage control of interleaved boost converter. Firstly, mathematical model of the interleaved boost converter is derived after that the method is applied. Besides, the interleaved boost converter is fed by a PV array under irradiation level and ambient temperature change. As a result of the simulation study, output voltage control of interleaved boost converter under reference voltage change is realized as desired.",book:{id:"11499",title:"Nonlinear Systems - Recent Developments and Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11499.jpg"},signatures:"Erdal Şehirli"},{id:"82973",title:"Compact Incoherent Multidimensional Imaging Systems Using Static Diffractive Coded Apertures",slug:"compact-incoherent-multidimensional-imaging-systems-using-static-diffractive-coded-apertures",totalDownloads:5,totalDimensionsCites:0,doi:"10.5772/intechopen.105864",abstract:"Incoherent holographic imaging technologies, in general, involve multiple optical components for beam splitting—combining and shaping—and in most cases, require an active optical device such as a spatial light modulator (SLM) for generating multiple phase-shifted holograms in time. The above requirements made the realization of holography-based products expensive, heavy, large, and slow. To successfully transfer the holography capabilities discussed in research articles to products, it is necessary to find methods to simplify holography architectures. In this book chapter, two important incoherent holography techniques, namely interference-based Fresnel incoherent correlation holography (FINCH) and interferenceless coded aperture correlation holography (I-COACH), have been successfully simplified in space and time using advanced manufacturing methods and nonlinear reconstruction, respectively. Both techniques have been realized in compact optical architectures using a single static diffractive optical element manufactured using lithography technologies. Randomly multiplexed diffractive lenses were manufactured using electron beam lithography for FINCH. A quasi-random lens and a mask containing a quasi-random array of pinholes were manufactured using electron beam lithography and photolithography, respectively, for I-COACH. In both cases, the compactification has been achieved without sacrificing the performances. The design, fabrication, and experiments of FINCH and I-COACH with static diffractive optical elements are presented in details.",book:{id:"11860",title:"Holography - Recent Advances and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11860.jpg"},signatures:"Vijayakumar Anand, Soon Hock Ng, Tomas Katkus, Daniel Smith, Vinoth Balasubramani, Denver P. Linklater, Pierre J. Magistretti, Christian Depeursinge, Elena P. Ivanova and Saulius Juodkazis"},{id:"82958",title:"Electromagnetic Relations between Materials and Fields for Microwave Chemistry",slug:"electromagnetic-relations-between-materials-and-fields-for-microwave-chemistry",totalDownloads:2,totalDimensionsCites:0,doi:"10.5772/intechopen.106257",abstract:"We consider the application of microwave energy to a material. The effects of the electromagnetic field on the material and of the material on the electromagnetic field will be described, focusing on the dielectric relaxation phenomenon of the liquid. The dielectric permittivity of mixtures is discussed by extending Debye relaxation to explain how the material behaves with respect to an electric field. We will also consider the energy that the electric field imparts to the material, both thermally and nonthermally. We will develop this relation and describe what form it should take if there is a nonthermal effect in the chemical reaction field under microwave irradiation.",book:{id:"11494",title:"Electric Field in Advancing Science and Technology",coverURL:"https://cdn.intechopen.com/books/images_new/11494.jpg"},signatures:"Sugiyama Jun-ichi, Sugiyama Hayato, Sato Chika and Morizumi Maki"},{id:"82961",title:"Mixed Reality Applications in Business Contexts",slug:"mixed-reality-applications-in-business-contexts",totalDownloads:4,totalDimensionsCites:0,doi:"10.5772/intechopen.106582",abstract:"Mixed reality is becoming increasingly relevant in business. In the corporate environment, such as logistics or maintenance, the use of data glasses allows extensive possibilities for process optimization and quality assurance. In the area of construction, virtual models either as augmentation of reality or mapped in virtual reality offer new approaches to experience ability. The goal of this paper is to show the manifold possibilities of mixed reality in the enterprise environment. For this purpose, selected application scenarios with corresponding realization stages will be shown and analyzed regarding their added value.",book:{id:"11860",title:"Holography - Recent Advances and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11860.jpg"},signatures:"Anett Mehler-Bicher, Lothar Steiger and Dirk Weitzel"},{id:"82951",title:"Decoupling Techniques for Coupled PDE Models in Fluid Dynamics",slug:"decoupling-techniques-for-coupled-pde-models-in-fluid-dynamics",totalDownloads:4,totalDimensionsCites:0,doi:"10.5772/intechopen.105997",abstract:"We review decoupling techniques for coupled PDE models in fluid dynamics. In particular, we are interested in the coupled models for fluid flow interacting with porous media flow and the fluid structure interaction (FSI) models. For coupled models for fluid flow interacting with porous media flow, we present decoupled preconditioning techniques, two-level and multilevel methods, Newton-type linearization-based two-level and multilevel algorithms, and partitioned time-stepping methods. The main theory and some numerical experiments are given to illustrate the effectiveness and efficiency of these methods. For the FSI models, partitioned time-stepping algorithms and a multirate time-stepping algorithm are carefully studied and analyzed. Numerical experiments are presented to highlight the advantages of these methods.",book:{id:"11862",title:"The Essence of Large-Eddy Simulations",coverURL:"https://cdn.intechopen.com/books/images_new/11862.jpg"},signatures:"Mingchao Cai, Mo Mu and Lian Zhang"}],onlineFirstChaptersTotal:43},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:330,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:9,numberOfPublishedChapters:139,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:123,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:112,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:21,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:11,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"August 2nd, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:33,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:6,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",slug:"ana-isabel-flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",slug:"christian-palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",slug:"francisco-javier-martin-romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. 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Kasenga",hash:"91cde4582ead884cb0f355a19b67cd56",volumeInSeries:4,fullTitle:"Malaria",editors:[{id:"86725",title:"Dr.",name:"Fyson",middleName:"Hanania",surname:"Kasenga",slug:"fyson-kasenga",fullName:"Fyson Kasenga",profilePictureURL:"https://mts.intechopen.com/storage/users/86725/images/system/86725.jpg",institutionString:"Malawi Adventist University",institution:{name:"Malawi Adventist University",institutionURL:null,country:{name:"Malawi"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7123",title:"Current Topics in Neglected Tropical Diseases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7123.jpg",slug:"current-topics-in-neglected-tropical-diseases",publishedDate:"December 4th 2019",editedByType:"Edited by",bookSignature:"Alfonso J. Rodriguez-Morales",hash:"61c627da05b2ace83056d11357bdf361",volumeInSeries:3,fullTitle:"Current Topics in Neglected Tropical Diseases",editors:[{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7064",title:"Current Perspectives in Human Papillomavirus",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7064.jpg",slug:"current-perspectives-in-human-papillomavirus",publishedDate:"May 2nd 2019",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"d92a4085627bab25ddc7942fbf44cf05",volumeInSeries:2,fullTitle:"Current Perspectives in Human Papillomavirus",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Bacterial Infectious Diseases",value:3,count:2},{group:"subseries",caption:"Parasitic Infectious Diseases",value:5,count:4},{group:"subseries",caption:"Viral Infectious Diseases",value:6,count:7}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:2},{group:"publicationYear",caption:"2021",value:2021,count:4},{group:"publicationYear",caption:"2020",value:2020,count:3},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:303,paginationItems:[{id:"280338",title:"Dr.",name:"Yutaka",middleName:null,surname:"Tsutsumi",slug:"yutaka-tsutsumi",fullName:"Yutaka Tsutsumi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/280338/images/7961_n.jpg",biography:null,institutionString:null,institution:{name:"Fujita Health University",country:{name:"Japan"}}},{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/116250/images/system/116250.jpg",biography:"Professor Nima Rezaei obtained an MD from Tehran University of Medical Sciences, Iran. He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). 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The applications of this research cover many related fields, such as biotechnology and medicine, where, for example, Bioinformatics contributes to faster drug design, DNA analysis in forensics, and DNA sequence analysis in the field of personalized medicine. Personalized medicine is a type of medical care in which treatment is customized individually for each patient. Personalized medicine enables more effective therapy, reduces the costs of therapy and clinical trials, and also minimizes the risk of side effects. Nevertheless, advances in personalized medicine would not have been possible without bioinformatics, which can analyze the human genome and other vast amounts of biomedical data, especially in genetics. The rapid growth of information technology enabled the development of new tools to decode human genomes, large-scale studies of genetic variations and medical informatics. The considerable development of technology, including the computing power of computers, is also conducive to the development of bioinformatics, including personalized medicine. In an era of rapidly growing data volumes and ever lower costs of generating, storing and computing data, personalized medicine holds great promises. Modern computational methods used as bioinformatics tools can integrate multi-scale, multi-modal and longitudinal patient data to create even more effective and safer therapy and disease prevention methods. Main aspects of the topic are: Applying bioinformatics in drug discovery and development; Bioinformatics in clinical diagnostics (genetic variants that act as markers for a condition or a disease); Blockchain and Artificial Intelligence/Machine Learning in personalized medicine; Customize disease-prevention strategies in personalized medicine; Big data analysis in personalized medicine; Translating stratification algorithms into clinical practice of personalized medicine.",annualVolume:11403,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",editor:{id:"351533",title:"Dr.",name:"Slawomir",middleName:null,surname:"Wilczynski",fullName:"Slawomir Wilczynski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035U1loQAC/Profile_Picture_1630074514792",institutionString:null,institution:{name:"Medical University of Silesia",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"5886",title:"Dr.",name:"Alexandros",middleName:"T.",surname:"Tzallas",fullName:"Alexandros Tzallas",profilePictureURL:"https://mts.intechopen.com/storage/users/5886/images/system/5886.png",institutionString:"University of Ioannina, Greece & Imperial College London",institution:{name:"University of Ioannina",institutionURL:null,country:{name:"Greece"}}},{id:"257388",title:"Distinguished Prof.",name:"Lulu",middleName:null,surname:"Wang",fullName:"Lulu Wang",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRX6kQAG/Profile_Picture_1630329584194",institutionString:"Shenzhen Technology University",institution:{name:"Shenzhen Technology University",institutionURL:null,country:{name:"China"}}},{id:"225387",title:"Prof.",name:"Reda R.",middleName:"R.",surname:"Gharieb",fullName:"Reda R. Gharieb",profilePictureURL:"https://mts.intechopen.com/storage/users/225387/images/system/225387.jpg",institutionString:"Assiut University",institution:{name:"Assiut University",institutionURL:null,country:{name:"Egypt"}}}]},{id:"8",title:"Bioinspired Technology and Biomechanics",keywords:"Bioinspired Systems, Biomechanics, Assistive Technology, Rehabilitation",scope:'Bioinspired technologies take advantage of understanding the actual biological system to provide solutions to problems in several areas. Recently, bioinspired systems have been successfully employing biomechanics to develop and improve assistive technology and rehabilitation devices. The research topic "Bioinspired Technology and Biomechanics" welcomes studies reporting recent advances in bioinspired technologies that contribute to individuals\' health, inclusion, and rehabilitation. Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',annualVolume:11404,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"49517",title:"Prof.",name:"Hitoshi",middleName:null,surname:"Tsunashima",fullName:"Hitoshi Tsunashima",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTP4QAO/Profile_Picture_1625819726528",institutionString:null,institution:{name:"Nihon University",institutionURL:null,country:{name:"Japan"}}},{id:"425354",title:"Dr.",name:"Marcus",middleName:"Fraga",surname:"Vieira",fullName:"Marcus Vieira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003BJSgIQAX/Profile_Picture_1627904687309",institutionString:null,institution:{name:"Universidade Federal de Goiás",institutionURL:null,country:{name:"Brazil"}}},{id:"196746",title:"Dr.",name:"Ramana",middleName:null,surname:"Vinjamuri",fullName:"Ramana Vinjamuri",profilePictureURL:"https://mts.intechopen.com/storage/users/196746/images/system/196746.jpeg",institutionString:"University of Maryland, Baltimore County",institution:{name:"University of Maryland, Baltimore County",institutionURL:null,country:{name:"United States of America"}}}]},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering",scope:"The Biotechnology - Biosensors, Biomaterials and Tissue Engineering topic within the Biomedical Engineering Series aims to rapidly publish contributions on all aspects of biotechnology, biosensors, biomaterial and tissue engineering. We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. 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