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These books synthesize perspectives of renowned scientists from the world’s most prestigious institutions - from Fukushima Renewable Energy Institute in Japan to Stanford University in the United States, including Columbia University (US), University of Sidney (AU), University of Miami (USA), Cardiff University (UK), and many others.
\\n\\nThis collaboration embodied the true essence of Open Access by simplifying the approach to OA publishing for Academic editors and authors who contributed their research and allowed the new research to be made available free and open to anyone anywhere in the world.
\\n\\nTo celebrate the 50 books published, we have gathered them at one location - just one click away, so that you can easily browse the subjects of your interest, download the content directly, share it or read online.
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IntechOpen and Knowledge Unlatched formed a partnership to support researchers working in engineering sciences by enabling an easier approach to publishing Open Access content. Using the Knowledge Unlatched crowdfunding model to raise the publishing costs through libraries around the world, Open Access Publishing Fee (OAPF) was not required from the authors.
\n\nInitially, the partnership supported engineering research, but it soon grew to include physical and life sciences, attracting more researchers to the advantages of Open Access publishing.
\n\n\n\nThese books synthesize perspectives of renowned scientists from the world’s most prestigious institutions - from Fukushima Renewable Energy Institute in Japan to Stanford University in the United States, including Columbia University (US), University of Sidney (AU), University of Miami (USA), Cardiff University (UK), and many others.
\n\nThis collaboration embodied the true essence of Open Access by simplifying the approach to OA publishing for Academic editors and authors who contributed their research and allowed the new research to be made available free and open to anyone anywhere in the world.
\n\nTo celebrate the 50 books published, we have gathered them at one location - just one click away, so that you can easily browse the subjects of your interest, download the content directly, share it or read online.
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The interest in robotics has been steadily increasing during the last decades. This concern has directly impacted the development of the novel theoretical research areas and products. This new book provides information about fundamental topics of serial and parallel manipulators such as kinematics & dynamics modeling, optimization, control algorithms and design strategies. I would like to thank all authors who have contributed the book chapters with their valuable novel ideas and current developments.",isbn:null,printIsbn:"978-953-51-0437-7",pdfIsbn:"978-953-51-5621-5",doi:"10.5772/2301",price:139,priceEur:155,priceUsd:179,slug:"serial-and-parallel-robot-manipulators-kinematics-dynamics-control-and-optimization",numberOfPages:470,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"ccdd21118a081fb3fada9ceddafa4192",bookSignature:"Serdar Kucuk",publishedDate:"March 30th 2012",coverURL:"https://cdn.intechopen.com/books/images_new/1876.jpg",numberOfDownloads:94177,numberOfWosCitations:38,numberOfCrossrefCitations:51,numberOfCrossrefCitationsByBook:18,numberOfDimensionsCitations:89,numberOfDimensionsCitationsByBook:17,hasAltmetrics:1,numberOfTotalCitations:178,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 10th 2011",dateEndSecondStepPublish:"April 25th 2011",dateEndThirdStepPublish:"September 30th 2011",dateEndFourthStepPublish:"October 14th 2011",dateEndFifthStepPublish:"March 15th 2012",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,7",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"5424",title:"Dr.",name:"Serdar",middleName:null,surname:"Küçük",slug:"serdar-kucuk",fullName:"Serdar Küçük",profilePictureURL:"https://mts.intechopen.com/storage/users/5424/images/system/5424.jpeg",biography:"Serdar Küçük received a BA and MSc from Marmara University, Istanbul, Turkey, in 1995 and 1998, respectively. He received a Ph.D. from Kocaeli University, Turkey, in 2004, where he is currently a full professor at the Department of Biomedical Engineering. He has several scientific publications to his credit, including international conference papers, journal papers, books, and book chapters. He serves as a reviewer for several well-known robotic journals. He is also an editor of scientific books. His research interests include optimization, control, and kinematics and dynamics modelling of serial and parallel robotic manipulators. 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\r\n\tA game as an activity and, at the same time, a basic tool of human education is important from his birth to death, but also from the first beginnings of human society to the present day. The discipline of game theory deals mainly with types, description, algorithmization, and strategies but also the formalization of games. From the point of view of the games themselves, it can be said that it is active from the idea to the practical game implementation. This book describes some modern approaches, procedures, and algorithms, but also the practical use of game theory and its development. The book will include, among other things, game classifications and formalization, themes of cooperative and non-cooperative games, symmetric and asymmetric games, zero and non-zero-sum games, simultaneous and turn-based (sequential) games, meta-games or games with complete and incomplete information, and infinitely long games. Last but not least, the book also creates a space for the relation of game theory and information technologies, strategy games and war games, economy and business games theory, or for gamification and education or training, including optimization, testing, and presentations of the games and their sociological impacts.
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His scientific research is focusing on computer graphics, parallel computing and especially virtual reality and related technologies.\n\nA researcher in virtual reality and related technologies, head of the LIRKIS DCI FEEI TU Košice (laboratory for research and development of new flexible and intelligent interfaces based on computer graphics and virtual reality technologies) and holder of 2 patents (Interactive school desk and Virtual control panel).",institutionString:"Technical University of Košice",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"3",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"Technical University of Košice",institutionURL:null,country:{name:"Slovakia"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"15",title:"Mathematics",slug:"mathematics"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"466998",firstName:"Dragan",lastName:"Miljak",middleName:"Anton",title:"Mr.",imageUrl:"https://mts.intechopen.com/storage/users/466998/images/21564_n.jpg",email:"dragan@intechopen.com",biography:"As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. 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To handle uncertainty in real world data, inexact parameters and constraints are combined with various kinds of optimization techniques. Often a detailed solution of an inexact programming optimization problem involves a large number of direct comparisons to interactively identify the uncertain relationships among the objective function and decision variables, whether the problems are medium-sized or larger-scaled. When these methods are applied to complicated and nonlinear problems, the number of direct comparisons can become exponential.
\nThe genetic algorithm (GA) method is a suitable optimization approach especially for solving problems that involve nonsmooth and multimodal search spaces. The GA-based optimization technique is suitable for solving linear and nonlinear programming optimization problems with inexact information; and the fields of application include operations research, industrial engineering and management science.
\nThis chapter is organized as follows. Section 2 presents the background and literature review of this research. Section 3 discusses the proposed GA-based methods for solving inexact linear programming (ILP), inexact quadratic programming (IQP) and inexact nonlinear programming (INLP) problems. Section 4 presents the case study of using GAINLP in the solution of an INLP problem of solid waste disposal planning. Section 5 is the conclusion.
\nEconomic optimization in the operation programming of solid waste management was first proposed in the 1960s [1]. Different models of waste management planning have been developed in the following decades. The primary considerations involved include cost control, environmental sustainability and waste reutilization. The techniques employed include linear programming [2–5], mixed integer linear programming [6], multiobjective programming [7–9], nonlinear programming [10, 11], as well as their hybrids, which involve probability, fuzzy set and inexact analysis [12–16]. Due to complexity of the nonlinear programming problems for solid waste management, research works in the area are scant; some exceptions include [17, 18].
\nThe approach of operational programming with inexact analysis often treats the uncertain parameters as intervals with known lower and upper bounds and unclear distributions. In real-life problems, while the available information is often inadequate and the distribution functions are often unknown, it is generally possible to represent the obtained data with inexact numbers that can be readily used in the inexact programming models. For decision makers, it is usually more feasible to represent uncertain information as inexact data than to specify distributions of fuzzy sets or probability functions. Hence, various kinds of inexact programming such as ILP, IQP, inexact integer programming (IIP), inexact dynamic programming (IDP) and inexact multiobjective programming (IMOP) have been developed and are well discussed [10, 11, 19]. It can be observed from these studies that applications of inexact models to practical solid waste planning systems are effective. These research reports demonstrated substantial effort has been developed to traditional binary analysis for ILP and IQP. However, traditional binary analysis methods for ILP and IQP involve unavoidable simplifications and assumptions, which often increase the chance for error in the problem-solving process and adversely affected the quality of the results. Moreover, a more complex model often increases the chance of error in the solution. It has been observed that more complex models often produce less optimal results, and studies that focus on INLP problems are scarce. For example, in [20], the methodology mainly focused on combining endpoint values of the inexact parameters to form a set of deterministic problems, which will only work for particular monotone functions within a small-scale model. Therefore, a more flexible problem-solving method for the general inexact optimization problems is desired.
\nEngineering problems that have traditionally been formulated as IQP or INLP problems often involve large and uneven search spaces, for which a global optimal solution is often not required. GA is a suitable optimization tool especially for solving complex and nonlinear problems, which involve nonsmooth and multimodal search spaces. Therefore, we suggest a GA-based method as a more effective problem-solving approach than the traditional inexact programming methods.
\nFor implementation of GA, the Genetic Algorithm Solver of Global Optimization Toolbox (GASGOT), developed by MATLAB (Trademark of MathWord), has been adopted. GASGOT implements simulated evolution in the MATLAB environment using both binary and floating point representations and the ordered base representation. This enables flexible implementation of the genetic operators, selection functions, termination functions and evaluation functions. GASGOT was developed by the Department of Industrial Engineering of North Carolina State University as a toolbox of MATLAB. Hence, it runs in a MATLAB workspace and can be easily invoked by other programs.
\nIn this study, the GA linear program solving engine of GASGOT has been adopted for ILP problems and GA nonlinear program solving engine of GASGOT has been adopted for IQP and INLP problems.
\nA typical ILP problem can be expressed as follows:\n
where \n
GA has been adopted for solving ILP problem. In this GA approach, the upper and lower bounds of the inexact numbers of coefficients \n
GAILP has been designed to include three stages, which are discussed as follows:
\nThe objective of the first stage is to get an initial suboptimal \n
Where \n
In the second stage, the inexact coefficients of \n
Substituting \n
To identify the coefficients \n
The coefficients \n
Meanwhile, the objective function presented in Eq. (5) can be constructed so as to find \n
There are two kinds of decision schemes for inexact programming problems, which are the conservative scheme and the optimistic scheme [21]. The former assumes less risk than the latter, so that for a maximization objective function, planning for the lower bound of an objective value represents the conservative scheme and planning for the upper bound of an objective value represents the optimistic scheme. In terms of constraints, the conservative scheme involves more rigorous or stringent constraints and the optimistic scheme adopts more tolerant ones.
\nThus, the problem of searching for \n
The problem,\n
will give \n
Hence, the values of \n
In the third stage, the problem represented in Eq. (1) is converted into the following two subproblems:
\nFor \n
For \n
This step eliminates the inexact parameters in Eq. (1) and generates instead Eq. (8) and Eq. (9) as typical linear programming (LP) problems, which can be solved easily.
\nGenerally speaking, the interactive binary algorithm (IBA) proposed in [19, 22] can be used for solving inexact linear problems reliably and relatively quickly. However, this binary algorithm has some limitations. One of them, for example, is the limitation that the upper and lower bounds of an inexact coefficient cannot have different signs. In contrast, the GAILP does not have this kind of limitation because the GA method does not depend on any assumed distribution of the inexact parameter. Hence, the GAILP method effectively extends the scope of problems solvable using the methods of ILP. It is more adaptable for real world applications of optimization problems with uncertainty.
\nA sample ILP problem in [22] is as follows,\n
where
By using the traditional IBA method [22], two submodels are obtained,\n
and\n
The results were \n
By using the GAILP, the results can be calculated with the following objective functions:\n
and\n
The results were \n
The GAILP method generates a solution, which is different from that obtained using the IBA proposed in [22]. A comparison will be discussed as follows:
\nFor the \n
Optimistic scheme,
Zoom-in of the optimistic scheme,
In Figures 1 to 4, the bold lines denote the boundaries of the constraints, which limit the possible values for \n
The boundaries, together with the
In Figures 1 to 4, the thin dotted lines are given by the IBA and the thin solid lines represent the objective functions given by the proposed GAILP method. The legends for Figure 1 to 4 are listed in Table 1.
\nConservative scheme,
Zoom-in of the conservative scheme,
The GAILP method can be extended to solve the IQP problems or other more complicated INLP problems.
\nA typical IQP problem is formulated as follows:\n
where \n
In stage one, to obtain an initial suboptimal \n
where \n
In the second stage, substituting \n
and\n
To determine \n
To obtain\n
In the third stage, the problem expressed in Eq. (11) has been converted into the following two subproblems:
\nFor \n
For \n
The inexact information has been incorporated in these two subproblems. These two subproblems, as typical nonlinear programming problems, can be solved by the GA nonlinear program solving engine of GASGOT.
\nQuadratic programming problems are specific cases of nonlinear programming problems. Due to the lack of generally applicable algorithms for handling the nonlinear structure and the inexact information embedded in the structure, most nonlinear programming problems are difficult to solve. The IBA method proposed in [11, 22] is not intended for dealing with generic nonlinear problems. In contrast, the GA-based method can be used as a general problem solver for this type of problems because there is not much difference for GA between treating the term of \n
In the following, a computation experiment will be conducted to illustrate how the GAINLP method can handle complicated inexact nonlinear problems. A sample INLP problem is as follows:\n
where \n
GAINLP has been designed to include the three stages of problem solving.
\nIn stage one, to obtain the initial suboptimal \n
Then, the heuristic search algorithm of the GA nonlinear program solving engine of GASGOT can be used to identify a suboptimal solution \n
In stage two, by substituting \n
and\n
To determine \n
and\n
The objective functions to get \n
and\n
By solving Eqs. (21)–(24), the values of all the inexact coefficients are obtained, i.e., \n
In stage three, the objective function presented in Eq. (20) is converted into the following two subproblems:\n
and\n
The inexact parameters in Eq. (20) have been eliminated, and two typical nonlinear optimization problems have been generated instead. The solution of the example (Eq. (19)) is\n
As demonstrated above, it can be seen that the GAINLP method can generate the optimal result without any simplification or assumption, and it can be adapted for applications of optimization problems with uncertainty. The next section demonstrates application of this method to a real world regional waste management problem.
\nSolid waste management is the process of removing waste materials from the surrounding environment, which involves the collection, separation, storage, processing, treatment, transport, recovery and disposal of solid waste. Landfill and incineration are two of the most commonly used solid waste disposal methods. The objective of a solid waste management process is to dispose discarded materials in a timely manner so as to prevent the spread of disease, minimize the likelihood of contamination and reduce their effects on human health and the environment.
\nThe economy of scale (ES) is a microeconomics term, and it refers to the advantages that enterprises obtain due to their size or scale of operation, with the cost per unit of output generally decreasing as the scale increases and fixed costs are distributed over more units of output. In a solid waste management system, ES exists within the transportation process [23] and it can be expressed as a sizing model with a power law [11].\n
where \n
Case study of municipalities and waste management facilities.
The study region includes three municipalities, a waste-to-energy (WTE) facility and a landfill, as shown in Figure 5. Three time periods are considered; each has an interval of five years. Over the 15-year planning horizon, an existing landfill and WTE facilities are available to serve the municipal solid waste (MSW) disposal needs in the region. The landfill has an existing capacity of \n
Table 2 shows the waste generation rates of the three municipalities and the operating costs of the two facilities in the three periods.
\nTime period | \nk=1 | \nk=2 | \nk=3 | \n
---|---|---|---|
Waste generation \n | \n|||
Municipality 1 ( | \n[260, 340] | \n[310, 390] | \n[360, 440] | \n
Municipality 2 ( | \n[160, 240] | \n[185, 265] | \n[210, 290] | \n
Municipality 3 ( | \n[260, 340] | \n[260, 340] | \n[310, 390] | \n
Operation cost \n | \n|||
Landfill ( | \n[30, 45] | \n[40, 60] | \n[50, 80] | \n
WTE facility ( | \n[55, 75] | \n[60, 85] | \n[65, 95] | \n
Data for the waste generation and treatment/disposal.
Taking into consideration the effects of the ES, the INLP model can be formulated as follows:\n
where
In this objective function (Eq. (26)), the first term on the right side reflects the transportation costs in each management period (
The MSW generation rates generally vary between different municipalities and for different periods, and the costs for the waste transportation and treatment also vary temporally and spatially. Furthermore, interactions exist between the waste flows and their transportation costs due to the effects of the ES (Eq. (25)). Table 3 and Table 4 show the parameters related to the ES, which include the fixed unit transportation cost \n
Fixed unit transportation cost ($/t) | \nReference waste flow (t/d) | \n||||||
---|---|---|---|---|---|---|---|
\n | \n\n | \n\n | \n\n | \n\n | \n\n | \n\n | \n\n | \n
City-to-landfill | \n|||||||
\n\n | \n[14.58, 19.40] | \n[16.04, 21.34] | \n[17.64, 23.48] | \n\n\n | \n[220, 250] | \n[240, 280] | \n[260, 320] | \n
\n\n | \n[12.65, 16.87] | \n[13.92, 18.56] | \n[15.31, 20.41] | \n\n\n | \n[160, 200] | \n[180, 220] | \n[220, 260] | \n
\n\n | \n[15.30, 20.49] | \n[16.83, 22.53] | \n[18.52, 24.79] | \n\n\n | \n[160, 200] | \n[180, 240] | \n[200, 240] | \n
City-to-WTE | \n|||||||
\n\n | \n[11.57, 15.42] | \n[12.73, 16.97] | \n[14.00, 18.66] | \n\n\n | \n[200, 240] | \n[240, 280] | \n[280, 320] | \n
\n\n | \n[12.17, 16.15] | \n[13.39, 17.76] | \n[14.73, 19.54] | \n\n\n | \n[120, 170] | \n[150, 190] | \n[180, 220] | \n
\n\n | \n[10.60, 14.10] | \n[11.67, 15.51] | \n[12.83, 17.06] | \n\n\n | \n[220, 270] | \n[220, 270] | \n[240, 270] | \n
WTE-to-landfill | \n|||||||
\n\n | \n[5.71, 7.62] | \n[6.28, 8.38] | \n[6.91, 9.33] | \n\n\n | \n[170, 200] | \n[200, 260] | \n[240, 270] | \n
Fixed unit transportation costs and reference waste flows.
\n | \nk=1 | \nk=2 | \nk=3 | \n\n | \nk=1 | \nk=2 | \nk=3 | \n
---|---|---|---|---|---|---|---|
\n\n | \n−2.7 | \n−3.4 | \n−3.8 | \n\n\n | \n−1.9 | \n−2.6 | \n−3.3 | \n
\n\n | \n−4.1 | \n−5.0 | \n−6.3 | \n\n\n | \n−3.1 | \n−4.0 | \n−5.0 | \n
\n\n | \n−1.7 | \n−2.1 | \n−2.8 | \n\n\n | \n−1.2 | \n−1.7 | \n−2.2 | \n
\n\n | \n−2.8 | \n−3.4 | \n−4.5 | \n\n\n | \n−2.3 | \n−2.8 | \n−3.6 | \n
\n\n | \n−2.1 | \n−2.5 | \n−3.1 | \n\n\n | \n−2.0 | \n−2.2 | \n−2.6 | \n
\n\n | \n−3.4 | \n−4.5 | \n−5.0 | \n\n\n | \n−3.2 | \n−3.5 | \n−3.9 | \n
\n\n | \n−0.8 | \n−1.1 | \n−1.4 | \n\n\n | \n−1.3 | \n−1.8 | \n−2.1 | \n
\n\n
Note: The + and – superscript sign of \n
Hence, it can be observed that the traditional IBA cannot solve this problem without additional assumptions or simplifications. The following discussion will explain how traditional methods solve this problem by simplifying the nonlinear effects of the ES.\n
(i) Let \n
(ii) Assuming\n
The left two columns of Table 5 list the solutions for \n
Both of the above simplifications introduce inaccuracy and limitations. When the value of
Applying the GAINLP model on the inexact nonlinear programming problem, the optimization problem can be solved directly without additional assumptions for the effects of the ES. Three different scenarios, (\n
The above three scenarios assume that the ES exponent is universal in the whole region during the entire period. However, this is not always necessarily true for practical engineering problems. More common situations may involve different scale exponents for various combinations of municipalities and facilities in different periods. Thus, Table 6 illustrates the solutions for the 4th scenario, which involves different scale exponents.
\nDecision variable(t/d) | \nILP solution | \nIQP solution | \nOther solutions | \n||
---|---|---|---|---|---|
m=−1 | \n−0.2< | \nm=−0.1 | \nm=−0.3 | \nm=−0.5 | \n|
\n\n | \n[210, 290] | \n[250, 290] | \n[203, 292] | \n[100, 221] | \n[35, 88] | \n
\n\n | \n0 | \n[310, 350] | \n[1, 36] | \n[1, 44] | \n[1, 36] | \n
\n\n | \n[0, 30] | \n[360, 440] | \n[1, 44] | \n[126, 190] | \n[240, 300] | \n
\n\n | \n0 | \n[0, 30] | \n[1, 43] | \n[60, 141] | \n[144, 240] | \n
\n\n | \n[0, 65] | \n[185, 225] | \n[1, 73] | \n[20, 103] | \n[75, 148] | \n
\n\n | \n[210, 290] | \n[50, 80] | \n[200, 290] | \n[200, 259] | \n[197, 260] | \n
\n\n | \n[0, 30] | \n0 | \n[1, 37] | \n[90, 190] | \n[225, 312] | \n
\n\n | \n[260, 330] | \n0 | \n[247, 332] | \n[189, 270] | \n[120, 200] | \n
\n\n | \n[170, 200] | \n0 | \n[154, 209] | \n[139, 210] | \n[143, 192] | \n
\n\n | \n50 | \n[10, 50] | \n[35, 58] | \n[120, 167] | \n[220, 307] | \n
\n\n | \n[310, 390] | \n[0, 40] | \n[295, 390] | \n[299, 385] | \n[295, 390] | \n
\n\n | \n[360, 410] | \n0 | \n[329, 426] | \n[202, 323] | \n[120, 161] | \n
\n\n | \n[160, 240] | \n[160, 210] | \n[147, 240] | \n[55, 145] | \n[1, 30] | \n
\n\n | \n[185, 200] | \n[0, 40] | \n[165, 222] | \n[142, 200] | \n[80, 154] | \n
\n\n | \n0 | \n[160, 210] | \n[1, 25] | \n[1, 40] | \n[1, 43] | \n
\n\n | \n[260, 310] | \n[260, 340] | \n[230, 320] | \n[122, 164] | \n[12, 40] | \n
\n\n | \n[0, 10] | \n[260, 340] | \n[1, 28] | \n[30, 100] | \n[108, 167] | \n
\n\n | \n[140, 190] | \n[310, 390] | \n[125, 200] | \n[125, 194] | \n[120, 214] | \n
\n\n | \n[220.2, 507.4] | \n[239.5, 514.1] | \n[209.8, 522.3] | \n[200.5, 519.6] | \n[197.6, 516.8] | \n
Solutions obtained by ILP model (
In the 4th scenario, the weight of the transportation cost in the system operation cost varies according to different \n
Decision variable | \nSolution (t/d) | \n\n | \nDecision variable | \nSolution (t/d) | \n\n | \n
---|---|---|---|---|---|
\n\n | \n[100, 192] | \n−0.15 | \n\n\n | \n[125, 189] | \n−0.1 | \n
\n\n | \n[0, 40] | \n−0.2 | \n\n\n | \n[300, 390] | \n−0.15 | \n
\n\n | \n[112, 178] | \n−0.35 | \n\n\n | \n[205, 312] | \n−0.15 | \n
\n\n | \n[65, 139] | \n−0.2 | \n\n\n | \n[42, 142] | \n−0.45 | \n
\n\n | \n[40, 78] | \n−0.3 | \n\n\n | \n[129, 192] | \n−0.3 | \n
\n\n | \n[199, 279] | \n−0.3 | \n\n\n | \n[0, 40] | \n−0.1 | \n
\n\n | \n[90, 189] | \n−0.25 | \n\n\n | \n[100, 198] | \n−0.3 | \n
\n\n | \n[135, 280] | \n−0.25 | \n\n\n | \n[44, 113] | \n−0.45 | \n
\n\n | \n[127, 218] | \n−0.3 | \n\n\n | \n[99, 219] | \n−0.4 | \n
\n\n | \n
Solutions when
Note: for transportation from WTE facility to landfill,
System cost comparisons.
The results also show that when the value of the ES exponent
In this chapter, the GA-based methods have been proposed and applied for identifying an all-purpose optimization solution for the ILP, IQP and INLP problems. These methods are called GAILP, GAIQP and GAINLP. Compared to these GA-based methods, the traditional problem-solving method has limitations due to the complexity involved in selecting the upper or lower bounds of variables and parameters when the subobjective functions are being constructed. The complexity arises due to the extensive computation and necessary associated assumptions and simplification. The solution procedures of the proposed GA-based optimization methods do not involve any such assumption or simplification, and the quality of the result is guaranteed. The GAINLP was applied to a solid waste management optimization problem, and the result analysis illustrates the practicality and flexibility of the proposed GAINLP method for solving more complex INLP problems.
\nGAILP, GAIQP and GAINLP have been implemented in MATLAB, and can be easily extended to include other nonlinear operation programming software packages so as to enhance the flexibility and efficiency of the problem-solving process. The GA-based heuristic optimization approach is flexible and it can be extended to find solutions for various types of operation programming scenarios that involve nonlinear optimization and inexact information. It can also be used as an all-purpose algorithm for economic optimizations.
\nThe authors gratefully acknowledge the support of the Canada Research Chair program and the Natural Sciences and Engineering Research Council of Canada.
\nThe COVID-19 pandemic began in China in late 2019 and is perhaps one of the biggest health threats the world has faced this century. This highly infectious disease spread quickly across the globe, mutating into a number of variants that have made containment extremely difficult. It is clear that this global pandemic will leave in its wake extensive social, economic and health impacts for many years to come and we are only just beginning to recognise the extent of its legacy.
During the outbreak, citizens around the world experienced significant restrictions in terms of their social and economic activities in the form of quarantining at home for prolonged periods of time so that social interaction (and thus, the ability of the virus to transmit between people) is limited. Behavioural guidelines to help prevent infection and slow the spread of disease have mandated the wearing of face coverings in confined spaces and recommended the adoption of a wide range of hygienic practices (for example frequent hand washing, cleansing surfaces more regularly and using hand sanitizer when hand washing was not possible). These measures have signified large-scale changes in behaviour that are psychologically burdensome for individuals to successfully achieve [1]. However, human behaviour plays a decisive role in in shaping the progression and spread of COVID-19 [2] and therefore it is a matter of urgency that behavioural scientists understand the psychological drivers that underpin such behaviour to help swiftly implement interventions to promote behavioural changes on a population level that are necessary to stem the spread of the virus and protect vulnerable groups from contagion [1, 3].
The Capability, Opportunity, Motivation-Behaviour (COM-B) model of behaviour change (Figure 1) [4] is widely used in behavioural science research to explore influences on behaviour. This model proposes that a person must have sufficient psychological and physical capability (strength, knowledge, skills, etc.), physical and social opportunity (time, social cues, etc.) as well as reflective and automatic motivation (intentions, planning, emotion regulation, etc.) to enact a given behaviour. Michie, West and Harvey [5] argue that each of these factors could contribute to lower levels of adherence than are needed to enact behaviours that prevent the spread of the COVID-19 virus. The COM-B model is at the centre of the Behaviour Change Wheel (BCW), which is a tool kit for designing tailored behaviour change interventions (BCIs) [6]. Thus, once a behavioural ‘diagnosis’ has been conducted utilising the components of the COM-B model, suitable targets for intervention can then be identified [1]. These targets will be the components of the COM-B that are most likely to influence a particular behaviour and can be developed into BCIs to improve adherence to protective health behaviours.
The COM-B model.
In this chapter, we apply the COM-B model to two key sets of COVID-19 transmission-related protective behaviours: ‘hygienic practices’ (including frequent hand washing and wearing a face covering) and ‘social distancing practices’ (involving staying at home where possible, keeping a 2-metre distance from others in public and not gathering in large groups). These behaviours are key in reducing transmission of the virus and it is likely that such measures will remain in place for some time in most countries, to some extent [7, 8]. Indeed, despite the inception of widespread vaccination programmes across the globe, maintaining protective behaviours will ensure the continued reduction in the spread of infection to mitigate low vaccination uptake rates, difficulties in vaccine supply and variants immune to the vaccine. It is vital therefore that behavioural scientists understand the psychological factors influencing such behaviours in the context of the COVID-19 pandemic within a theoretical framework to feed into efforts to promote continued adherence to essential protective behaviours.
To inform BCIs, an understanding of the drivers that underpin protective behaviours are required, along with a deeper exploration that addresses the nuances in how people might understand, accept and adhere to such a set of behaviours. As yet, there is a dearth of evidence relating to how protective behavioural practices could be adopted on a population-wide level [4] and so it is important to assess behavior under the current adverse circumstances. Protective behaviours are largely under the volitional control of individuals, in that one can choose whether or not to follow the suggested practices. Further, whilst wearing a face covering and washing or sanitising hands in specified situations represents a fairly clear set of actions, the actions required to achieve ‘social distancing’ successfully are arguably more complex and nuanced. Some social distancing behaviours rely on the individual themselves committing to and enacting the behaviour (e.g., staying at home) and others require the reciprocal observance of others (e.g., gathering in groups, close contact greetings). We also know that social isolation could have a negative impact on health and well-being, which impacts upon decisions about adherence to behaviours [9].
Whilst there is a wide and good-quality literature on the enactment of hygiene behaviour, especially handwashing [10], we know little about these behaviours in the current context where the drivers of behaviour and nature of the threat may be entirely different from usual circumstances.
The term ‘social distancing’ has been coined during the pandemic and is complex and nuanced. Although large-scale population surveys have shown that social distancing practices have been sustained as the pandemic unfolded and citizens generally support these measures (e.g., [11, 12, 13]), there is evidence that motivation to comply over time may be threatened by other psychological factors. For example, as psychological resources are cumulatively depleted over time with lengthy and repeated lockdowns [11]; as competing drivers of behaviour begin to take priority (e.g., the inherent drive for social connection) [14]; as confidence in the government reduces [15]; and ‘moral’ judgements impact upon decision making [16] adherence to social distancing practices may diminish.
Indeed, evidence suggests that the extent to which different groups of individuals have been willing and able to comply with these important protective behaviours is mixed. Population surveys have found that 1 in 4 individuals struggle to follow social distancing guidelines, due to difficulties in meeting up with family or friends outside because of bad weather or feeling worn out by the pandemic [11, 17]. For other groups in society, it is likely that enacting social distancing behaviours is difficult for other, more practical, reasons. For example, individuals who do not have access to a garden, those who share private spaces with other families, or those who are required to work outside the home may not have the opportunity to comply and are inevitably at increased risk of exposure and infection [18]. These ‘structural’ factors are likely to be more impactful on the ability to comply with social distancing in groups who are already disadvantaged and who are faring worse due to the pandemic – reflecting the ‘slow burn of inequality’ exposed by epidemics, described by Marmot [19].
Exploring protective behaviours in relation to the COM-B is useful for understanding the conditions that must be in place for these behaviours to be successfully enacted and therefore developing BCIs that promote adherence. We conducted this investigation using data from a large-scale survey of UK citizens.
The COVID-19 Psychological Research Consortium (C19PRC) Study (www.sheffield.ac.uk/psychology-consortium-covid19) is a longitudinal study mapping changes in behaviour and mental health over time from the very early days of the COVID-19 outbreak. The C19PRC study has collected data from 2025 participants in five waves over 12 months (March 2020–March 2021) from the four UK Nations, with comparable data sets from Ireland, Italy, Spain, and Saudi Arabia. A multitude of detailed demographic, health, behavioural and psychosocial measures have been collected, including socio-demographic characteristics, health status, depression, anxiety, traumatic stress, somatic symptoms, loneliness, resilience as well as health behaviours and lifestyle habits (see McBride et al. for full methodology [20, 21]). We modelled the complex relationships between the social, physical and mental health of our sample and conducted extended behavioural analyses on protective behaviours and the COM-B model [17, 22, 23, 24, 25, 26].
Participants self-reported motivation, capability and opportunity to enact protective behaviours in the C19PRC survey. Items were adapted from a preliminary version of the COM-B self-evaluation questionnaire and other guidelines (COM-B-Qv1) [4, 6] and respondents indicated the extent to which seventeen statements were true for them during the COVID-19 pandemic on a 5–point scale (labelled: strongly agree, agree, neither agree nor disagree, disagree, strongly disagree). Three items measured psychological capability: e.g., “I knew about why it was important and had a clear idea about how the virus was transmitted”. Two items measured physical opportunity: e.g., “It was easy for me to do it” and four items measured social opportunity: e.g., “I had support from others”. Five items measured reflective motivation: e.g., “I intended to do it” and three items measured automatic motivation: e.g., “I would feel bad if I didn’t do it”.
Analysis of the C19PRC data revealed three main themes in relation to protective behaviours. First, we identified specific components of the COM-B model that drive different types of protective behaviours. Second, we identified specific demographic groups that have particular difficulties with such behaviours. And third, there are significant emotional drivers that influence adherence to protective behaviours.
The first set of behaviours explored in Wave 1 during the first lockdown in the UK (March 2020) were five self-reported hygienic practices: Touching eyes or mouth, washing hands with soap and water more often, using hand sanitising gel if soap and water were not available, using disinfectants to wash surfaces in the home more frequently and covering nose and mouth with a tissue or sleeve when coughing or sneezing. Response scales were ‘No’, ‘Occasionally’ and ‘Whenever possible’.
After controlling for demographic variables (age, gender, ethnicity, income, etc.), psychological capability, social opportunity and reflective motivation predicted hygienic practices most and reflective motivation had the largest influence [20]. This means that adults who knew why hygienic practices were effective in reducing the transmission of the virus, who had social support, and had made plans to carry out hygienic practices were more likely to successfully carry out these protective health behaviours. Notably, we observed that older age and higher levels of household income were associated with more engagement with hygienic practices. Hygienic practices were practiced less by males (compared to females) and those living in suburban areas (compared to those living in more rural areas).
For social distancing behaviours, participants in Wave 2 (April 2020) self-reported which behaviours in the past week they had engaged in, out of seven social distancing practices; e.g., “Stayed at least 2 metres (6ft) away from other people when in”, “Met up with friends or extended family (outside of your home)”; “Engaged in close contact greetings with people outside of your family (e.g., shaking hands, hugging)”; “Gathered in a group of more than two people in a park and other public space”. These behaviours represented clear violations of or adherence to social distancing guidelines in the first UK lockdown (responses were: Not at all, 1–2 days a week, 3–4 days a week, Most days, Every day).
Here, a different picture emerged. Of the COM-B components, only Psychological Capability exhibited a direct and positive association with adherence to social distancing [21]. Older adults and city dwellers were more likely to report higher levels of psychological capability and women were more likely to report increased motivation for social distancing. As with hygienic practices, those with higher levels of education and income were more likely to practice social distancing.
We explored adherence to social distancing further using a list experiment, embedded in Wave 4 of the C-19PRC survey (December 2020). This method allows researchers to measure responses to sensitive items that may normally invoke untrue or inaccurate answers due to social desirability concerns. The C19PRC survey list experiment used four control states and included a fifth sensitive item, as follows:
“We would now like to ask you how willing you are to break rules or conventions. Please look at the following list of common rules and indicate how many of these you have done in the last 6 months:
I have driven a car at more than 100 miles an hour.
I have travelled illegally to North Korea.
I have sometimes not paid my bills on time.
I have borrowed something from a friend and forgotten to return it.
I have socialised in another household during lockdown (
One-quarter of our sample revealed that they had violated government guidelines by socialising in another household during lockdown. An examination of whether any particular social or psychological factors were associated with agreement to the sensitive item, we found that the only statistically significant predictor was anxiety related to COVID-19. This anxiety was in response to the question ‘How anxious are you about the coronavirus COVID-19 pandemic?’; participants were provided with a ‘slider’ (electronic visual analogue scale) to indicate their degree of anxiety with ‘0’ and ‘100’ at the left- and right-hand extremes, respectively, and 10-point increments. This produced continuous scores ranging from 0 to 100 with higher scores reflecting higher levels of COVID-19-related anxiety. This factor was negatively correlated with agreement to the sensitive item - indicating that experience of COVID-related anxiety was strongly associated with a tendency to follow the lockdown rules.
Previous research has found that emotions are an important influencing factor in the behavioural responses to pandemics; in particular, worry has been found to motivate action to control danger [27]. Liao et al. [28] conducted a multi-wave longitudinal survey study in Hong Kong during the influenza A(H7N9) pandemic and reported that worry about infection from the virus was positively associated with the enactment of protective behaviours (e.g., avoiding crowds, rescheduling travel plans). The authors reported that, as worry about the virus changed over time, so did protective behaviours, implying a causal link between worry and engaging in protective behaviours. Other evidence from the Swine Flu pandemic also illustrates how emotional status mediates behavioural responses; Jones and Salathe [29] reported that self-reported anxiety over the epidemic mediated the likelihood that US citizens engaged in protective behaviours such as social distancing. Exploring emotional factors that might mediate protective behavioural responses during the current pandemic, may help enormously with the design of BCIs to promote the enactment of essential protective behaviours such as social distancing.
The findings of the C19PRC Study in relation to the COM-B have clear implications for the design of BCIs to promote protective behaviours at a population level. For hygienic practices, interventions should focus on increasing and maintaining motivation to act and should contain behaviour change techniques (BCTs) that focus on self-regulatory processes involving planning and goal setting. We have suggested utilising implementation intentions, a specific planning technique found to help successfully bridge the ‘intention-behaviour’ gap [30, 31]. Further, to make it feasible that individuals are able to enact such techniques independently (e.g., during the lockdown), we suggest utilising the compendium of self-enactment BCTs [32] in intervention design (self-regulatory techniques #5 - #18 are especially relevant for hygienic practices). Our data show that groups in particular need of targeting for interventions to increase hygienic practices are males and those living in cities and suburbs.
For social distancing, interventions should focus on increasing psychological capability and include BCTs that bolster knowledge around social distancing and why it is important, to enable citizens to develop psychological skills in enacting and maintaining these behaviours. For increasing psychological capability, it is important that it is clear why social distancing is important and how social contact transmits the virus; as well as specifying the situations in which social distancing should be enacted and exactly how to do that. BCIs would help people to overcome physical or psychological barriers to action (or inaction) and should be specifically tailored to those sociodemographic groups who display particular difficulties in enacting social distancing, namely, younger people and those living in cities. For those with lower incomes and lower levels of education, who may struggle with social distancing for more practical reasons, wider functions of intervention from the BCW would need to be employed, whereby economic and social policy would assist in overcoming practical or structural barriers to enable these groups to follow guidelines (e.g., if working from home is not possible, ensuring COVID-safe workspaces where social distancing is achievable and implementing paid time off for isolation). It is important that individuals who feel anxious about COVID-19 are supported in managing their anxiety levels.
This chapter has explored psychological and demographic influences on citizens’ ability to enact protective behaviours during the COVID-19 pandemic. We have discussed how enacting social distancing and hygienic practices are influenced by different components of the COM-B model and made recommendations for intervention. Behavioural scientists face the challenge of urgently developing interventions that help citizens to maintain adherence to protective behaviours to control the spread of the COVID-19 virus.
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\n\nIn recent years, supply chains in the manufacturing industry have become more and more complicated, and many cases of supply chain disruptions due to natural disasters have been confirmed. It is necessary for manufacturers to build a system that can help them alleviate losses and shorten recovery periods due to supply chain disruptions. Supplier diversification, as well as supplier evaluation and selection, are discussed as risk aversion measures in many papers. However, even if the procurement source has been evaluated enough, there are problems, such as opportunity loss during recovery periods and soaring procurement costs during normal periods. In this chapter, to help Japanese manufacturers to alleviate opportunity loss under component procurement disruption situations and keep cost competitiveness in normal periods, decision-making models of supply chain structure assessment, supplier selection, procurement allocation, and trading contracts are designed and verified.
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',book:{id:"11082",title:"Operations Management",coverURL:"https://cdn.intechopen.com/books/images_new/11082.jpg"},signatures:"Călin Corciovă, Robert Fuior, Doru Andriţoi and Cătălina Luca"},{id:"81687",title:"Managing Foodservice Quality in the Foodservice Industry",slug:"managing-foodservice-quality-in-the-foodservice-industry",totalDownloads:2,totalDimensionsCites:0,doi:"10.5772/intechopen.104800",abstract:"Quality has become a value that enables businesses to survive and continue existing. Henceforth, food industries need to entrench quality into their business performance. Foodservice quality is characterized as a service that bears on its ability to satisfy stated or implied needs and service free of defects. Foodservice businesses are an integral part of social life, both biologically and socially, biologically as satisfying the nutrition requirements of the society and socially in terms of addressing socialization and esthetics-pleasure values. 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He has both an MS and Ph.D. in Biomedical Engineering. He was previously a research scientist at the University of California Los Angeles (UCLA) and visiting professor and researcher at the University of North Dakota. He is currently working in artificial intelligence and its applications in medical signal processing. In addition, he is using digital signal processing in medical imaging and speech processing. Dr. Asadpour has developed brain-computer interfacing algorithms and has published books, book chapters, and several journal and conference papers in this field and other areas of intelligent signal processing. He has also designed medical devices, including a laser Doppler monitoring system.",institutionString:"Kaiser Permanente Southern California",institution:null},{id:"169608",title:"Prof.",name:"Marian",middleName:null,surname:"Găiceanu",slug:"marian-gaiceanu",fullName:"Marian Găiceanu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/169608/images/system/169608.png",biography:"Prof. Dr. Marian Gaiceanu graduated from the Naval and Electrical Engineering Faculty, Dunarea de Jos University of Galati, Romania, in 1997. He received a Ph.D. (Magna Cum Laude) in Electrical Engineering in 2002. Since 2017, Dr. Gaiceanu has been a Ph.D. supervisor for students in Electrical Engineering. He has been employed at Dunarea de Jos University of Galati since 1996, where he is currently a professor. Dr. Gaiceanu is a member of the National Council for Attesting Titles, Diplomas and Certificates, an expert of the Executive Agency for Higher Education, Research Funding, and a member of the Senate of the Dunarea de Jos University of Galati. He has been the head of the Integrated Energy Conversion Systems and Advanced Control of Complex Processes Research Center, Romania, since 2016. He has conducted several projects in power converter systems for electrical drives, power quality, PEM and SOFC fuel cell power converters for utilities, electric vehicles, and marine applications with the Department of Regulation and Control, SIEI S.pA. (2002–2004) and the Polytechnic University of Turin, Italy (2002–2004, 2006–2007). He is a member of the Institute of Electrical and Electronics Engineers (IEEE) and cofounder-member of the IEEE Power Electronics Romanian Chapter. He is a guest editor at Energies and an academic book editor for IntechOpen. He is also a member of the editorial boards of the Journal of Electrical Engineering, Electronics, Control and Computer Science and Sustainability. Dr. Gaiceanu has been General Chairman of the IEEE International Symposium on Electrical and Electronics Engineering in the last six editions.",institutionString:'"Dunarea de Jos" University of Galati',institution:{name:'"Dunarea de Jos" University of Galati',country:{name:"Romania"}}},{id:"4519",title:"Prof.",name:"Jaydip",middleName:null,surname:"Sen",slug:"jaydip-sen",fullName:"Jaydip Sen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/4519/images/system/4519.jpeg",biography:"Jaydip Sen is associated with Praxis Business School, Kolkata, India, as a professor in the Department of Data Science. His research areas include security and privacy issues in computing and communication, intrusion detection systems, machine learning, deep learning, and artificial intelligence in the financial domain. He has more than 200 publications in reputed international journals, refereed conference proceedings, and 20 book chapters in books published by internationally renowned publishing houses, such as Springer, CRC press, IGI Global, etc. Currently, he is serving on the editorial board of the prestigious journal Frontiers in Communications and Networks and in the technical program committees of a number of high-ranked international conferences organized by the IEEE, USA, and the ACM, USA. He has been listed among the top 2% of scientists in the world for the last three consecutive years, 2019 to 2021 as per studies conducted by the Stanford University, USA.",institutionString:"Praxis Business School",institution:null},{id:"320071",title:"Dr.",name:"Sidra",middleName:null,surname:"Mehtab",slug:"sidra-mehtab",fullName:"Sidra Mehtab",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00002v6KHoQAM/Profile_Picture_1584512086360",biography:"Sidra Mehtab has completed her BS with honors in Physics from Calcutta University, India in 2018. She has done MS in Data Science and Analytics from Maulana Abul Kalam Azad University of Technology (MAKAUT), Kolkata, India in 2020. Her research areas include Econometrics, Time Series Analysis, Machine Learning, Deep Learning, Artificial Intelligence, and Computer and Network Security with a particular focus on Cyber Security Analytics. Ms. Mehtab has published seven papers in international conferences and one of her papers has been accepted for publication in a reputable international journal. She has won the best paper awards in two prestigious international conferences – BAICONF 2019, and ICADCML 2021, organized in the Indian Institute of Management, Bangalore, India in December 2019, and SOA University, Bhubaneswar, India in January 2021. Besides, Ms. Mehtab has also published two book chapters in two books. Seven of her book chapters will be published in a volume shortly in 2021 by Cambridge Scholars’ Press, UK. Currently, she is working as the joint editor of two edited volumes on Time Series Analysis and Forecasting to be published in the first half of 2021 by an international house. Currently, she is working as a Data Scientist with an MNC in Delhi, India.",institutionString:"NSHM College of Management and Technology",institution:null},{id:"226240",title:"Dr.",name:"Andri Irfan",middleName:null,surname:"Rifai",slug:"andri-irfan-rifai",fullName:"Andri Irfan Rifai",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/226240/images/7412_n.jpg",biography:"Andri IRFAN is a Senior Lecturer of Civil Engineering and Planning. He completed the PhD at the Universitas Indonesia & Universidade do Minho with Sandwich Program Scholarship from the Directorate General of Higher Education and LPDP scholarship. He has been teaching for more than 19 years and much active to applied his knowledge in the project construction in Indonesia. His research interest ranges from pavement management system to advanced data mining techniques for transportation engineering. He has published more than 50 papers in journals and 2 books.",institutionString:null,institution:{name:"Universitas Internasional Batam",country:{name:"Indonesia"}}},{id:"314576",title:"Dr.",name:"Ibai",middleName:null,surname:"Laña",slug:"ibai-lana",fullName:"Ibai Laña",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314576/images/system/314576.jpg",biography:"Dr. Ibai Laña works at TECNALIA as a data analyst. He received his Ph.D. in Artificial Intelligence from the University of the Basque Country (UPV/EHU), Spain, in 2018. He is currently a senior researcher at TECNALIA. His research interests fall within the intersection of intelligent transportation systems, machine learning, traffic data analysis, and data science. He has dealt with urban traffic forecasting problems, applying machine learning models and evolutionary algorithms. He has experience in origin-destination matrix estimation or point of interest and trajectory detection. Working with large volumes of data has given him a good command of big data processing tools and NoSQL databases. He has also been a visiting scholar at the Knowledge Engineering and Discovery Research Institute, Auckland University of Technology.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"314575",title:"Dr.",name:"Jesus",middleName:null,surname:"L. Lobo",slug:"jesus-l.-lobo",fullName:"Jesus L. Lobo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314575/images/system/314575.png",biography:"Dr. Jesús López is currently based in Bilbao (Spain) working at TECNALIA as Artificial Intelligence Research Scientist. In most cases, a project idea or a new research line needs to be investigated to see if it is good enough to take into production or to focus on it. That is exactly what he does, diving into Machine Learning algorithms and technologies to help TECNALIA to decide whether something is great in theory or will actually impact on the product or processes of its projects. So, he is expert at framing experiments, developing hypotheses, and proving whether they’re true or not, in order to investigate fundamental problems with a longer time horizon. He is also able to design and develop PoCs and system prototypes in simulation. He has participated in several national and internacional R&D projects.\n\nAs another relevant part of his everyday research work, he usually publishes his findings in reputed scientific refereed journals and international conferences, occasionally acting as reviewer and Programme Commitee member. Concretely, since 2018 he has published 9 JCR (8 Q1) journal papers, 9 conference papers (e.g. ECML PKDD 2021), and he has co-edited a book. He is also active in popular science writing data science stories for reputed blogs (KDNuggets, TowardsDataScience, Naukas). Besides, he has recently embarked on mentoring programmes as mentor, and has also worked as data science trainer.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"103779",title:"Prof.",name:"Yalcin",middleName:null,surname:"Isler",slug:"yalcin-isler",fullName:"Yalcin Isler",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRyQ8QAK/Profile_Picture_1628834958734",biography:"Yalcin Isler (1971 - Burdur / Turkey) received the B.Sc. degree in the Department of Electrical and Electronics Engineering from Anadolu University, Eskisehir, Turkey, in 1993, the M.Sc. degree from the Department of Electronics and Communication Engineering, Suleyman Demirel University, Isparta, Turkey, in 1996, the Ph.D. degree from the Department of Electrical and Electronics Engineering, Dokuz Eylul University, Izmir, Turkey, in 2009, and the Competence of Associate Professorship from the Turkish Interuniversity Council in 2019.\n\nHe was Lecturer at Burdur Vocational School in Suleyman Demirel University (1993-2000, Burdur / Turkey), Software Engineer (2000-2002, Izmir / Turkey), Research Assistant in Bulent Ecevit University (2002-2003, Zonguldak / Turkey), Research Assistant in Dokuz Eylul University (2003-2010, Izmir / Turkey), Assistant Professor at the Department of Electrical and Electronics Engineering in Bulent Ecevit University (2010-2012, Zonguldak / Turkey), Assistant Professor at the Department of Biomedical Engineering in Izmir Katip Celebi University (2012-2019, Izmir / Turkey). He is an Associate Professor at the Department of Biomedical Engineering at Izmir Katip Celebi University, Izmir / Turkey, since 2019. In addition to academics, he has also founded Islerya Medical and Information Technologies Company, Izmir / Turkey, since 2017.\n\nHis main research interests cover biomedical signal processing, pattern recognition, medical device design, programming, and embedded systems. He has many scientific papers and participated in several projects in these study fields. He was an IEEE Student Member (2009-2011) and IEEE Member (2011-2014) and has been IEEE Senior Member since 2014.",institutionString:null,institution:{name:"Izmir Kâtip Çelebi University",country:{name:"Turkey"}}},{id:"339677",title:"Dr.",name:"Mrinmoy",middleName:null,surname:"Roy",slug:"mrinmoy-roy",fullName:"Mrinmoy Roy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/339677/images/16768_n.jpg",biography:"An accomplished Sales & Marketing professional with 12 years of cross-functional experience in well-known organisations such as CIPLA, LUPIN, GLENMARK, ASTRAZENECA across different segment of Sales & Marketing, International Business, Institutional Business, Product Management, Strategic Marketing of HIV, Oncology, Derma, Respiratory, Anti-Diabetic, Nutraceutical & Stomatological Product Portfolio and Generic as well as Chronic Critical Care Portfolio. A First Class MBA in International Business & Strategic Marketing, B.Pharm, D.Pharm, Google Certified Digital Marketing Professional. Qualified PhD Candidate in Operations and Management with special focus on Artificial Intelligence and Machine Learning adoption, analysis and use in Healthcare, Hospital & Pharma Domain. Seasoned with diverse therapy area of Pharmaceutical Sales & Marketing ranging from generating revenue through generating prescriptions, launching new products, and making them big brands with continuous strategy execution at the Physician and Patients level. Moved from Sales to Marketing and Business Development for 3.5 years in South East Asian Market operating from Manila, Philippines. Came back to India and handled and developed Brands such as Gluconorm, Lupisulin, Supracal, Absolut Woman, Hemozink, Fabiflu (For COVID 19), and many more. In my previous assignment I used to develop and execute strategies on Sales & Marketing, Commercialization & Business Development for Institution and Corporate Hospital Business portfolio of Oncology Therapy Area for AstraZeneca Pharma India Ltd. Being a Research Scholar and Student of ‘Operations Research & Management: Artificial Intelligence’ I published several pioneer research papers and book chapters on the same in Internationally reputed journals and Books indexed in Scopus, Springer and Ei Compendex, Google Scholar etc. Currently, I am launching PGDM Pharmaceutical Management Program in IIHMR Bangalore and spearheading the course curriculum and structure of the same. I am interested in Collaboration for Healthcare Innovation, Pharma AI Innovation, Future trend in Marketing and Management with incubation on Healthcare, Healthcare IT startups, AI-ML Modelling and Healthcare Algorithm based training module development. I am also an affiliated member of the Institute of Management Consultant of India, looking forward to Healthcare, Healthcare IT and Innovation, Pharma and Hospital Management Consulting works.",institutionString:null,institution:{name:"Lovely Professional University",country:{name:"India"}}},{id:"310576",title:"Prof.",name:"Erick Giovani",middleName:null,surname:"Sperandio Nascimento",slug:"erick-giovani-sperandio-nascimento",fullName:"Erick Giovani Sperandio Nascimento",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y00002pDKxDQAW/ProfilePicture%202022-06-20%2019%3A57%3A24.788",biography:"Prof. Erick Sperandio is the Lead Researcher and professor of Artificial Intelligence (AI) at SENAI CIMATEC, Bahia, Brazil, also working with Computational Modeling (CM) and HPC. He holds a PhD in Environmental Engineering in the area of Atmospheric Computational Modeling, a Master in Informatics in the field of Computational Intelligence and Graduated in Computer Science from UFES. He currently coordinates, leads and participates in R&D projects in the areas of AI, computational modeling and supercomputing applied to different areas such as Oil and Gas, Health, Advanced Manufacturing, Renewable Energies and Atmospheric Sciences, advising undergraduate, master's and doctoral students. He is the Lead Researcher at SENAI CIMATEC's Reference Center on Artificial Intelligence. In addition, he is a Certified Instructor and University Ambassador of the NVIDIA Deep Learning Institute (DLI) in the areas of Deep Learning, Computer Vision, Natural Language Processing and Recommender Systems, and Principal Investigator of the NVIDIA/CIMATEC AI Joint Lab, the first in Latin America within the NVIDIA AI Technology Center (NVAITC) worldwide program. He also works as a researcher at the Supercomputing Center for Industrial Innovation (CS2i) and at the SENAI Institute of Innovation for Automation (ISI Automação), both from SENAI CIMATEC. He is a member and vice-coordinator of the Basic Board of Scientific-Technological Advice and Evaluation, in the area of Innovation, of the Foundation for Research Support of the State of Bahia (FAPESB). He serves as Technology Transfer Coordinator and one of the Principal Investigators at the National Applied Research Center in Artificial Intelligence (CPA-IA) of SENAI CIMATEC, focusing on Industry, being one of the six CPA-IA in Brazil approved by MCTI / FAPESP / CGI.br. He also participates as one of the representatives of Brazil in the BRICS Innovation Collaboration Working Group on HPC, ICT and AI. He is the coordinator of the Work Group of the Axis 5 - Workforce and Training - of the Brazilian Strategy for Artificial Intelligence (EBIA), and member of the MCTI/EMBRAPII AI Innovation Network Training Committee. He is the coordinator, by SENAI CIMATEC, of the Artificial Intelligence Reference Network of the State of Bahia (REDE BAH.IA). He leads the working group of experts representing Brazil in the Global Partnership on Artificial Intelligence (GPAI), on the theme \"AI and the Pandemic Response\".",institutionString:"Manufacturing and Technology Integrated Campus – SENAI CIMATEC",institution:null},{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/1063/images/system/1063.png",biography:"Prof. Dr. Constantin Voloşencu graduated as an engineer from\nPolitehnica University of Timișoara, Romania, where he also\nobtained a doctorate degree. He is currently a full professor in\nthe Department of Automation and Applied Informatics at the\nsame university. Dr. Voloşencu is the author of ten books, seven\nbook chapters, and more than 160 papers published in journals\nand conference proceedings. He has also edited twelve books and\nhas twenty-seven patents to his name. He is a manager of research grants, editor in\nchief and member of international journal editorial boards, a former plenary speaker, a member of scientific committees, and chair at international conferences. His\nresearch is in the fields of control systems, control of electric drives, fuzzy control\nsystems, neural network applications, fault detection and diagnosis, sensor network\napplications, monitoring of distributed parameter systems, and power ultrasound\napplications. He has developed automation equipment for machine tools, spooling\nmachines, high-power ultrasound processes, and more.",institutionString:"Polytechnic University of Timişoara",institution:{name:"Polytechnic University of Timişoara",country:{name:"Romania"}}},{id:"221364",title:"Dr.",name:"Eneko",middleName:null,surname:"Osaba",slug:"eneko-osaba",fullName:"Eneko Osaba",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/221364/images/system/221364.jpg",biography:"Dr. Eneko Osaba works at TECNALIA as a senior researcher. He obtained his Ph.D. in Artificial Intelligence in 2015. He has participated in more than twenty-five local and European research projects, and in the publication of more than 130 papers. He has performed several stays at universities in the United Kingdom, Italy, and Malta. Dr. Osaba has served as a program committee member in more than forty international conferences and participated in organizing activities in more than ten international conferences. He is a member of the editorial board of the International Journal of Artificial Intelligence, Data in Brief, and Journal of Advanced Transportation. He is also a guest editor for the Journal of Computational Science, Neurocomputing, Swarm, and Evolutionary Computation and IEEE ITS Magazine.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"275829",title:"Dr.",name:"Esther",middleName:null,surname:"Villar-Rodriguez",slug:"esther-villar-rodriguez",fullName:"Esther Villar-Rodriguez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/275829/images/system/275829.jpg",biography:"Dr. Esther Villar obtained a Ph.D. in Information and Communication Technologies from the University of Alcalá, Spain, in 2015. She obtained a degree in Computer Science from the University of Deusto, Spain, in 2010, and an MSc in Computer Languages and Systems from the National University of Distance Education, Spain, in 2012. Her areas of interest and knowledge include natural language processing (NLP), detection of impersonation in social networks, semantic web, and machine learning. Dr. Esther Villar made several contributions at conferences and publishing in various journals in those fields. Currently, she is working within the OPTIMA (Optimization Modeling & Analytics) business of TECNALIA’s ICT Division as a data scientist in projects related to the prediction and optimization of management and industrial processes (resource planning, energy efficiency, etc).",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"49813",title:"Dr.",name:"Javier",middleName:null,surname:"Del Ser",slug:"javier-del-ser",fullName:"Javier Del Ser",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49813/images/system/49813.png",biography:"Prof. Dr. Javier Del Ser received his first PhD in Telecommunication Engineering (Cum Laude) from the University of Navarra, Spain, in 2006, and a second PhD in Computational Intelligence (Summa Cum Laude) from the University of Alcala, Spain, in 2013. He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. He is a Senior Member of the IEEE, and a recipient of the Biscay Talent prize for his academic career.",institutionString:"Tecnalia Research & Innovation",institution:null},{id:"278948",title:"Dr.",name:"Carlos Pedro",middleName:null,surname:"Gonçalves",slug:"carlos-pedro-goncalves",fullName:"Carlos Pedro Gonçalves",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRcmyQAC/Profile_Picture_1564224512145",biography:'Carlos Pedro Gonçalves (PhD) is an Associate Professor at Lusophone University of Humanities and Technologies and a researcher on Complexity Sciences, Quantum Technologies, Artificial Intelligence, Strategic Studies, Studies in Intelligence and Security, FinTech and Financial Risk Modeling. He is also a progammer with programming experience in:\n\nA) Quantum Computing using Qiskit Python module and IBM Quantum Experience Platform, with software developed on the simulation of Quantum Artificial Neural Networks and Quantum Cybersecurity;\n\nB) Artificial Intelligence and Machine learning programming in Python;\n\nC) Artificial Intelligence, Multiagent Systems Modeling and System Dynamics Modeling in Netlogo, with models developed in the areas of Chaos Theory, Econophysics, Artificial Intelligence, Classical and Quantum Complex Systems Science, with the Econophysics models having been cited worldwide and incorporated in PhD programs by different Universities.\n\nReceived an Arctic Code Vault Contributor status by GitHub, due to having developed open source software preserved in the \\"Arctic Code Vault\\" for future generations (https://archiveprogram.github.com/arctic-vault/), with the Strategy Analyzer A.I. module for decision making support (based on his PhD thesis, used in his Classes on Decision Making and in Strategic Intelligence Consulting Activities) and QNeural Python Quantum Neural Network simulator also preserved in the \\"Arctic Code Vault\\", for access to these software modules see: https://github.com/cpgoncalves. He is also a peer reviewer with outsanding review status from Elsevier journals, including Physica A, Neurocomputing and Engineering Applications of Artificial Intelligence. Science CV available at: https://www.cienciavitae.pt//pt/8E1C-A8B3-78C5 and ORCID: https://orcid.org/0000-0002-0298-3974',institutionString:"University of Lisbon",institution:{name:"Universidade Lusófona",country:{name:"Portugal"}}},{id:"241400",title:"Prof.",name:"Mohammed",middleName:null,surname:"Bsiss",slug:"mohammed-bsiss",fullName:"Mohammed Bsiss",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241400/images/8062_n.jpg",biography:null,institutionString:null,institution:null},{id:"276128",title:"Dr.",name:"Hira",middleName:null,surname:"Fatima",slug:"hira-fatima",fullName:"Hira Fatima",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/276128/images/14420_n.jpg",biography:"Dr. Hira Fatima\nAssistant Professor\nDepartment of Mathematics\nInstitute of Applied Science\nMangalayatan University, Aligarh\nMobile: no : 8532041179\nhirafatima2014@gmal.com\n\nDr. Hira Fatima has received his Ph.D. degree in pure Mathematics from Aligarh Muslim University, Aligarh India. Currently working as an Assistant Professor in the Department of Mathematics, Institute of Applied Science, Mangalayatan University, Aligarh. She taught so many courses of Mathematics of UG and PG level. Her research Area of Expertise is Functional Analysis & Sequence Spaces. She has been working on Ideal Convergence of double sequence. She has published 17 research papers in National and International Journals including Cogent Mathematics, Filomat, Journal of Intelligent and Fuzzy Systems, Advances in Difference Equations, Journal of Mathematical Analysis, Journal of Mathematical & Computer Science etc. She has also reviewed few research papers for the and international journals. She is a member of Indian Mathematical Society.",institutionString:null,institution:null},{id:"414880",title:"Dr.",name:"Maryam",middleName:null,surname:"Vatankhah",slug:"maryam-vatankhah",fullName:"Maryam Vatankhah",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Borough of Manhattan Community College",country:{name:"United States of America"}}},{id:"414879",title:"Prof.",name:"Mohammad-Reza",middleName:null,surname:"Akbarzadeh-Totonchi",slug:"mohammad-reza-akbarzadeh-totonchi",fullName:"Mohammad-Reza Akbarzadeh-Totonchi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Ferdowsi University of Mashhad",country:{name:"Iran"}}},{id:"414878",title:"Prof.",name:"Reza",middleName:null,surname:"Fazel-Rezai",slug:"reza-fazel-rezai",fullName:"Reza Fazel-Rezai",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"American Public University System",country:{name:"United States of America"}}},{id:"302698",title:"Dr.",name:"Yao",middleName:null,surname:"Shan",slug:"yao-shan",fullName:"Yao Shan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Dalian University of Technology",country:{name:"China"}}},{id:"125911",title:"Prof.",name:"Jia-Ching",middleName:null,surname:"Wang",slug:"jia-ching-wang",fullName:"Jia-Ching Wang",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Central University",country:{name:"Taiwan"}}},{id:"357085",title:"Mr.",name:"P. 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Shukla",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Indian Institute of Technology Kanpur",country:{name:"India"}}},{id:"356823",title:"MSc.",name:"Seonghee",middleName:null,surname:"Min",slug:"seonghee-min",fullName:"Seonghee Min",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Daegu University",country:{name:"Korea, South"}}},{id:"353307",title:"Prof.",name:"Yoosoo",middleName:null,surname:"Oh",slug:"yoosoo-oh",fullName:"Yoosoo Oh",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:"Yoosoo Oh received his Bachelor's degree in the Department of Electronics and Engineering from Kyungpook National University in 2002. He obtained his Master’s degree in the Department of Information and Communications from Gwangju Institute of Science and Technology (GIST) in 2003. In 2010, he received his Ph.D. degree in the School of Information and Mechatronics from GIST. In the meantime, he was an executed team leader at Culture Technology Institute, GIST, 2010-2012. In 2011, he worked at Lancaster University, the UK as a visiting scholar. In September 2012, he joined Daegu University, where he is currently an associate professor in the School of ICT Conver, Daegu University. Also, he served as the Board of Directors of KSIIS since 2019, and HCI Korea since 2016. From 2017~2019, he worked as a center director of the Mixed Reality Convergence Research Center at Daegu University. From 2015-2017, He worked as a director in the Enterprise Supporting Office of LINC Project Group, Daegu University. His research interests include Activity Fusion & Reasoning, Machine Learning, Context-aware Middleware, Human-Computer Interaction, etc.",institutionString:null,institution:{name:"Daegu Gyeongbuk Institute of Science and Technology",country:{name:"Korea, South"}}},{id:"262719",title:"Dr.",name:"Esma",middleName:null,surname:"Ergüner Özkoç",slug:"esma-erguner-ozkoc",fullName:"Esma Ergüner Özkoç",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Başkent University",country:{name:"Turkey"}}},{id:"346530",title:"Dr.",name:"Ibrahim",middleName:null,surname:"Kaya",slug:"ibrahim-kaya",fullName:"Ibrahim Kaya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Izmir Kâtip Çelebi University",country:{name:"Turkey"}}},{id:"419199",title:"Dr.",name:"Qun",middleName:null,surname:"Yang",slug:"qun-yang",fullName:"Qun Yang",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Auckland",country:{name:"New Zealand"}}}]}},subseries:{item:{id:"20",type:"subseries",title:"Animal Nutrition",keywords:"Sustainable Animal Diets, Carbon Footprint, Meta Analyses",scope:"An essential part of animal production is nutrition. Animals need to receive a properly balanced diet. One of the new challenges we are now faced with is sustainable animal diets (STAND) that involve the 3 P’s (People, Planet, and Profitability). We must develop animal feed that does not compete with human food, use antibiotics, and explore new growth promoters options, such as plant extracts or compounds that promote feed efficiency (e.g., monensin, oils, enzymes, probiotics). These new feed options must also be environmentally friendly, reducing the Carbon footprint, CH4, N, and P emissions to the environment, with an adequate formulation of nutrients.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/20.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11416,editor:{id:"175967",title:"Dr.",name:"Manuel",middleName:null,surname:"Gonzalez Ronquillo",slug:"manuel-gonzalez-ronquillo",fullName:"Manuel Gonzalez Ronquillo",profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",biography:"Dr. Manuel González Ronquillo obtained his doctorate degree from the University of Zaragoza, Spain, in 2001. He is a research professor at the Faculty of Veterinary Medicine and Animal Husbandry, Autonomous University of the State of Mexico. He is also a level-2 researcher. He received a Fulbright-Garcia Robles fellowship for a postdoctoral stay at the US Dairy Forage Research Center, Madison, Wisconsin, USA in 2008–2009. He received grants from Alianza del Pacifico for a stay at the University of Magallanes, Chile, in 2014, and from Consejo Nacional de Ciencia y Tecnología (CONACyT) to work in the Food and Agriculture Organization’s Animal Production and Health Division (AGA), Rome, Italy, in 2014–2015. He has collaborated with researchers from different countries and published ninety-eight journal articles. He teaches various degree courses in zootechnics, sheep production, and agricultural sciences and natural resources.\n\nDr. Ronquillo’s research focuses on the evaluation of sustainable animal diets (StAnD), using native resources of the region, decreasing carbon footprint, and applying meta-analysis and mathematical models for a better understanding of animal production.",institutionString:null,institution:{name:"Universidad Autónoma del Estado de México",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,series:{id:"13",title:"Veterinary Medicine and Science",doi:"10.5772/intechopen.73681",issn:"2632-0517"},editorialBoard:[{id:"175762",title:"Dr.",name:"Alfredo J.",middleName:null,surname:"Escribano",slug:"alfredo-j.-escribano",fullName:"Alfredo J. 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The considerable development of technology, including the computing power of computers, is also conducive to the development of bioinformatics, including personalized medicine. In an era of rapidly growing data volumes and ever lower costs of generating, storing and computing data, personalized medicine holds great promises. Modern computational methods used as bioinformatics tools can integrate multi-scale, multi-modal and longitudinal patient data to create even more effective and safer therapy and disease prevention methods. Main aspects of the topic are: Applying bioinformatics in drug discovery and development; Bioinformatics in clinical diagnostics (genetic variants that act as markers for a condition or a disease); Blockchain and Artificial Intelligence/Machine Learning in personalized medicine; Customize disease-prevention strategies in personalized medicine; Big data analysis in personalized medicine; Translating stratification algorithms into clinical practice of personalized medicine.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",keywords:"Biomedical Data, Drug Discovery, Clinical Diagnostics, Decoding Human Genome, AI in Personalized Medicine, Disease-prevention Strategies, Big Data Analysis in Medicine"},{id:"8",title:"Bioinspired Technology and Biomechanics",scope:'Bioinspired technologies take advantage of understanding the actual biological system to provide solutions to problems in several areas. Recently, bioinspired systems have been successfully employing biomechanics to develop and improve assistive technology and rehabilitation devices. The research topic "Bioinspired Technology and Biomechanics" welcomes studies reporting recent advances in bioinspired technologies that contribute to individuals\' health, inclusion, and rehabilitation. 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Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"June 24th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:4,numberOfPublishedChapters:314,numberOfPublishedBooks:31,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. 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Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",annualVolume:11410,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. 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Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",annualVolume:11413,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},{id:"18",title:"Proteomics",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://mts.intechopen.com/storage/users/81926/images/system/81926.png",institutionString:"Suez Canal University",institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/50513",hash:"",query:{},params:{id:"50513"},fullPath:"/chapters/50513",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var m;(m=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(m)}()