\\n\\n
IntechOpen Book Series will also publish a program of research-driven Thematic Edited Volumes that focus on specific areas and allow for a more in-depth overview of a particular subject.
\\n\\nIntechOpen Book Series will be launching regularly to offer our authors and editors exciting opportunities to publish their research Open Access. We will begin by relaunching some of our existing Book Series in this innovative book format, and will expand in 2022 into rapidly growing research fields that are driving and advancing society.
\\n\\nLaunching 2021
\\n\\nArtificial Intelligence, ISSN 2633-1403
\\n\\nVeterinary Medicine and Science, ISSN 2632-0517
\\n\\nBiochemistry, ISSN 2632-0983
\\n\\nBiomedical Engineering, ISSN 2631-5343
\\n\\nInfectious Diseases, ISSN 2631-6188
\\n\\nPhysiology (Coming Soon)
\\n\\nDentistry (Coming Soon)
\\n\\nWe invite you to explore our IntechOpen Book Series, find the right publishing program for you and reach your desired audience in record time.
\\n\\nNote: Edited in October 2021
\\n"}]',published:!0,mainMedia:{caption:"",originalUrl:"/media/original/132"}},components:[{type:"htmlEditorComponent",content:'With the desire to make book publishing more relevant for the digital age and offer innovative Open Access publishing options, we are thrilled to announce the launch of our new publishing format: IntechOpen Book Series.
\n\nDesigned to cover fast-moving research fields in rapidly expanding areas, our Book Series feature a Topic structure allowing us to present the most relevant sub-disciplines. Book Series are headed by Series Editors, and a team of Topic Editors supported by international Editorial Board members. Topics are always open for submissions, with an Annual Volume published each calendar year.
\n\nAfter a robust peer-review process, accepted works are published quickly, thanks to Online First, ensuring research is made available to the scientific community without delay.
\n\nOur innovative Book Series format brings you:
\n\nIntechOpen Book Series will also publish a program of research-driven Thematic Edited Volumes that focus on specific areas and allow for a more in-depth overview of a particular subject.
\n\nIntechOpen Book Series will be launching regularly to offer our authors and editors exciting opportunities to publish their research Open Access. We will begin by relaunching some of our existing Book Series in this innovative book format, and will expand in 2022 into rapidly growing research fields that are driving and advancing society.
\n\nLaunching 2021
\n\nArtificial Intelligence, ISSN 2633-1403
\n\nVeterinary Medicine and Science, ISSN 2632-0517
\n\nBiochemistry, ISSN 2632-0983
\n\nBiomedical Engineering, ISSN 2631-5343
\n\nInfectious Diseases, ISSN 2631-6188
\n\nPhysiology (Coming Soon)
\n\nDentistry (Coming Soon)
\n\nWe invite you to explore our IntechOpen Book Series, find the right publishing program for you and reach your desired audience in record time.
\n\nNote: Edited in October 2021
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"685",leadTitle:null,fullTitle:"Epilepsy - Histological, Electroencephalographic and Psychological Aspects",title:"Epilepsy",subtitle:"Histological, Electroencephalographic and Psychological Aspects",reviewType:"peer-reviewed",abstract:"With the vision of including authors from different parts of the world, different educational backgrounds, and offering open-access to their published work, InTech proudly presents the latest edited book in epilepsy research, Epilepsy: Histological, electroencephalographic, and psychological aspects. 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The variety of conditions under which heat exchangers operate in specific engineering subsystems requires an individualized approach to the model solutions that have been developed for these systems modernizing. New tube systems for commercial heat exchangers have undergone industrial testing and are in successful operation at a wide range of thermal power plants.
Extending the service life and increasing the operational efficiency and reliability of heat exchangers in steam turbine units at thermal power plants are of great current interest. Modernizing heat exchangers, operating at thermal power plants, involves less expense than replacing the entire heat exchanger and is mainly aimed at eliminating structural defects that have been identified. This is done both when worn out components are replaced and in the course of planned major overhauls, so that the efficiency and operational reliability of the heat exchangers and the steam turbine unit, as a whole, can be increased substantially.
The major engineering solutions for improvement of commercial heat exchangers in thermal power plants steam turbine units must, first of all, be directed at enhancing the efficiency and reliability of their tube systems, since they are the most subject to wear during operation. The choice of approaches and modern engineering solutions for heat exchangers improvement must meet a number of specifications including the following [1]:
taking into consideration the specific operating conditions;
raising the efficiency of heat exchanger while retaining reliability or increasing reliability while maintaining efficiency;
improving or sustaining repairability and maintainability;
meeting the standards and rules of the supervisory agency Rostekhnadzor.
The improvement of heat exchangers is a rather complicated system problem. A large number of factors at different levels which influence the efficiency and reliability of a heat exchanger should be taken into account, along with its relationship to the engineering subsystems of steam turbine unit of a thermal power plant. The choice of a modernization scheme involves solving a specific optimization problem where the target function or criterion determining the choice may be any of various characteristics, such as raising the thermal efficiency or the thermal capacity of heat exchanger, or increasing its operational reliability or repairability.
The approach determination for heat exchanger improvement can be divided structurally into three stages: a stage for analyzing the initial data, a stage of computations and accounting for a number of operational and design-engineering factors and a stage of technical and economic analysis and evaluation. One of the most important stages in the analysis is the use of computational methods which take most complete account of the features and behavior of the processes occurring in steam turbine heat exchangers. These methods are used to calculate separately heat transfer coefficients for two heat transfer media, while individual factors affecting the heat transfer are taken into account by introducing corrections to heat transfer coefficients base values. When estimating a choice of improvement method, each specific heat exchanger is considered as a component of a particular engineering subsystem of steam turbine (condensation unit, system for regenerative feed water heating, system of hot water heating, etc.) in which it is employed; here the effect of the proposed modernization scheme on other elements of the subsystem or on the turbine unit as a whole is evaluated.
When improvements are made in heat exchangers at thermal power plants under operating conditions, it is necessary to analyze and take into account a large number of factors and performance indicators, including the specific operating conditions. Most often it is possible to optimize only the basic (thermal and hydraulic) operating characteristics of heat exchanger, leaving the others at levels corresponding to commercial apparatuses.
Over many years the authors have proposed, tested and brought to realization a series of new, by now commercial, technical solutions for modernizing a large number of different heat exchangers for steam turbine units; these have provided satisfactory solutions of the problems arising during heat exchanger operation, such as [1—3]:
retaining the external connector dimensions (through pipes and shells) of commercial equipment without change;
estimation of the choice of material for tube systems and shell components (water chambers);
use of high efficiency profiled tubes of different materials with optimal profiling parameters (Fig.1);
optimization of the tube bundles configuration in heat exchangers (in some cases — the increase of heat transfer surface within the shell sizes of commercial heat exchangers);
optimization of the intermediate partitions arrangement, the rise of tube system vibrational reliability by installing damper belts and clamps;
employing of a high efficiency method for tubes to tube sheets fixing with the use of annular reliefs made in the tube sheet metal;
efficient sealing of gaps between the intermediate partitions and the shell (for heat exchangers of “liquid — liquid” type);
use of special protective coatings.
External view and cross section of profiled twisted tube.
Retrofitting of the oil supply systems of turbine units is intended not only to recover indices characterizing their efficiency and environmental security but also to carry out measures that will improve their characteristics without significant financial and material outlays. These problems may be solved on the basis of technical considerations aimed primarily at oil coolers design.
Our analysis of the efficiency and in-service reliability of over 150 serially produced oil coolers, as well as the data of the Ural All-Russia Thermal Engineering Institute on the vulnerability to damage of oil coolers in service at steam-turbine units, has shown that the elements of these heat-exchangers most susceptible to damage are their tube bundles.
A summary of this data and also the results of tests on a number of apparatuses and experience with their operation under different conditions allowed us to formulate the main lines along which commercially produced oil coolers should be modernized. They are as follows:
the selection of advanced materials for the elements of the construction;
the use of heat exchange surfaces that augment heat transfer;
the creation of optimized layouts for the tube bundles;
the sealing of gaps in the oil space of the apparatuses;
the improvement of the reliability of tubes fixing to the tube sheet;
the protection of the tube sheets against corrosion.
Below, these lines will be considered in more detail.
When selecting the material for the structural elements of an oil cooler, several factors should be taken into account, such as the corrosiveness of the cooling water and the associated corrosion resistance of the heat-transfer tubes; the thermal and hydraulic characteristics of the tubes and their adhesive properties; the compatibility of different materials in one apparatus; the technological features of an assembly of apparatuses with the tubes made of the material selected; and also considerations of cost. The casing of the oil cooler and its parts are usually made of carbon-steel sheets and the tube sheets — of carbon-steel plates or from different types of brass. At most thermal power stations, tubes of brass L68 are installed in the oil coolers; this does not comply with present-day requirements. If a feasibility study is conducted and tubes of corrosion-resistant steels are used in the oil coolers, water chambers and tube sheets made of steels 12Cr18Ni10Ti or Cr23Ni17Mo2Ti can be manufactured. Lately stainless steel tubes are being installed more and more frequently in oil coolers. Considering the higher corrosiveness of the cooling water and the more stringent requirements for environmental safety of thermal power stations, in our opinion, the latter solution is more expedient.
When using stainless-steel tubes in oil coolers, one should bear in mind that the heating capacity of the apparatuses has decreased, because the thermal conductance of the steel is 6—7 times lower than that of brass.
Lately, the problem of using titanium alloy tubes in the tube bundles of heat exchangers has been widely discussed. Note that, notwithstanding the high corrosion-resistant and adhesive properties of titanium, several problems in its use still exist, such as protection of the “ferrous” metal of the tube sheets against electrochemical corrosion if it contacts the titanium and the insufficient resistance of titanium to friction wear and its corrosion instability in alkaline solutions with a pH > 10. Note also that the cost of titanium is higher than that of other materials.
The larger overall dimensions of oil coolers for high-power turbine installations required their developers and manufacturers to revise several basic concepts in the design of apparatuses associated, in particular, with the use of new heat exchange surfaces that augment the process of heat transfer, using variously profiled and finned tubes.
We know oil coolers that have tubes with spiral rolled finning, longitudinal welded finning, spiral wire mesh finning, and other kinds of finning. The comparatively new MP-165 and MP-330 oil coolers (for the K-300-240, K-500-240 and K-800-240 turbines manufactured by LMZ), with stainless steel tubes and cross fins manufactured by LMZ instead of the previously manufactured M-240 and M-540 oil coolers, are very efficient products. However, these new designs have, in our opinion, one shortcoming — comparatively low oil velocity, which is due to the non-optimal tube bundle layout in the apparatus.
Optimization of the tube bundle layout in heat exchangers, oil coolers included, is one of the most promising ways for improving them. It should be carried out on the basis of a comprehensive calculation of the thermal, hydrodynamic, and reliability characteristics of every given apparatus. The technique for such an optimization calculation has been worked out for oil coolers [4—7] both with plain and with twisted profiled tubes (TPT) that are used in power engineering (see Fig.1). It allows us to account for changes in the parameters of oil in different zones of the apparatus that have been selected downstream of the oil flow. One of the main factors determining the operating efficiency of oil coolers is the leakage of oil through the orifices in the intermediate partition plates and in gaps between the intermediate partition plates and the oil cooler shell. This factor is accounted for in another way.
The permeability of oil through an intermediate partition orifice in the oil cooler was studied at an experimental facility that simulated its geometrical, thermal, and physical performance parameters. The outside diameter of a working tube is 16 mm, the diameter of the orifice in an intermediate partition plate is 16.4 mm, and the thickness of a partition plate is 3 mm. In the experiments we used turbine oil UT30 with a temperature from 35 to 65 °C. The difference in the oil pressures on the partition plate ranged from 850 to 2910 Pa. All the experiments were carried out with the tube centered relative to the orifice in the intermediate partition plate.
Note that the well-known physical laws of liquid flow through an annular slot were confirmed in this study, and the quantitative and qualitative results allowed us to find more exact operating characteristics of oil coolers and to account for them in their designs. The oil flow rate through the annular slot increases as the oil temperature t
In contrast to existing methods, the more exact technique developed by us for calculations of oil coolers employs the zone-by-zone approach and accounts for changes in the oil parameters along the oil flow through the tube bundle (Fig. 2). In this case, the oil space of the oil cooler is divided by the partition plates into a number of zones: the input zone (I), the output zone (N), and intermediate zones (from I to N) in between. The heights of the zones correspond to the distances between the adjacent partition plates.
Scheme of oil flow in an element of a tube bundle of an oil cooler with partition plates of the “disc-ring” type and with unsealed gaps. δ1, δ2, δ3 are the gaps between the shell and annular partition plate, in the orifices of the annular and disc partition plates; Go is the oil flow rate through the tube bundle
In every zone, the oil is separated into two or three flows:
Calculations executed in accordance with the above technique make it possible to optimize the layout of the tube bundles for the oil coolers and to determine such specifics as the number of rows of tubes that are removed from the center of the tube bundle; the distance between the tubes (the back pitch); the distance between the intermediate partition plates, that is, the number of passes for oil; and others.
It is known that one of the most important elements determining the operating reliability of an oil cooler is the joint attaching the tubes to the tube sheet. Operating experience with shell-and-tube apparatuses shows that mechanical flaring of tubes in the smooth orifices of the tube sheets (the usual way of attaching the tubes) does not ensure a reliable tightness of the joint. It depends on the following factors: the influence of heat cycles in different directions, the inherent and forced vibrations of the tubes in the bundle and in the apparatus as a whole, the corrosive effect of the cooling water, the natural aging of the material of tubes and tube sheets, etc. [1,2].
An improved tightness and reliability of the joint between the tubes and the tube sheets can be obtained by applying a new technology developed by the specialists of the St. Petersburg State Nautical Technical University. It amounts to flaring the tubes using annular reliefs on the metal in the orifices of the tube sheet, which are formed with the aid of a special tool (Fig. 3).
Method for attaching tubes to tube plates. (a) An orifice in the tube sheet with annular reliefs; (b) assembly of attachment of the tube to the tube plate after flaring
To find the optimal dimensions, shape, position, and mechanical characteristics of the annular reliefs, computational studies and experiments were conducted that gave the following results:
in the area of the annular relief, the contact pressure increases considerably (by two to three times);
the optimal shape of the relief from the standpoint of most complete imbedding into the tube surface is a triangle with a smooth transition from the base to the walls of the orifice (Fig. 3 a);
the optimal height of the projection on the relief is in the range from 0.07 to 0.15 mm;
the maximum increase in contact pressure is obtained when the hardness of the surface of the projection is higher by 30 to 35% on average than the hardness of the metal of the tube sheet;
the annular relief should be located at a distance of at least 5 mm from the boundary of the zone where the tube is attached (flared) in the tube plate.
We checked the efficiency (reliability) of this technology of attachment on one-tube specimens, pilot modules, and a number of commercial apparatuses having tubes of different materials. On the basis of our investigations, we established that the given method provides a higher tightness than other previously known methods used in oil coolers do, and it is actually not inferior to the combined joint with flaring and welding. Nevertheless, note that the labor required by the proposed method is greater than with usual flaring by 25 to 30%. However, this may be justified.
It is known that the tube sheets of oil coolers can be protected against corrosion due to the cooling water in several ways:
by rational choice of the material;
by applying metal coatings and coatings based on paints, glass enamels, different resins, etc.
In oil coolers manufacturing, it is expedient to use corrosion-proof materials for the protection of the tube sheets or to apply metal coatings to them. In operation, the surface may be coated with an epoxy resin or minimum.
All the above considerations and advanced concepts on improvement of steam-turbine units oil coolers were the basis for modernizing a number of commercially produced oil coolers (MB-63-90; MB-40-60; MP-37; M-21; MOU-12; MO-11; MKh-4), which was done in accordance with our development works. The main measures in retrofitting the oil coolers were taken on the tube bundle, the element most vulnerable to damage in the apparatus. In doing this [1—3]:
optimization of the layout of the tube bundle is carried out;
the peripheral annular gap between the intermediate partition plates and the shell of the oil cooler is sealed with an oil-resistant rubber or Teflon plastic (Fig. 4);
stainless steel twisted profiled tubes (see Fig. 1), whose profile parameters are selected to conform to special apparatuses and conditions of their operation, are employed;
a new technology for attaching the tubes to the tube plates with annular reliefs is introduced (see above);
the tube sheets are protected against corrosion.
As an example, in Fig. 5 we find the approximated results of comparative tests of an MP-37 oil cooler for a K-100-90 turbine in the Verkhnetagil district power station before and after retrofitting. From the figure we see that the oil outlet temperature of the retrofitted oil cooler is 0.5 to 2.5°C lower than that of a commercially produced oil cooler. Moreover, note that the operating efficiency of the commercially produced plain-tube apparatus conformed to the designed one. Similar results were obtained for other retrofitted oil coolers, as well.
Up to 10 years of operating experience with modernized oil coolers showed that they ensure the reliable service of the apparatuses without any reduction in their thermal efficiency. No remarks about them were received from the operating personnel.
The seal between an annular partition plate and the shell of the oil cooler. (1) shell; (2) bolt with a nut; (3) clamping ring; (4) annular partition plate; (5) oil-resistant rubber (plasticized rubber)
By early 2000, the commercially produced oil coolers used in the lubrication systems of all LMZ K-800-240 turbines operating in the Russian Federation had worked out their service life and the question of replacing them arose. Although commercially produced M-540 oil coolers with wire-loop finning were available, replacement of the old oil coolers with these new ones turned to be inexpedient because the design of M-540 oil coolers had considerable shortcomings. The authors of this paper have developed a highly efficient and environmentally safe MB-270-330 shell-and-tube oil cooler with disk-ring partitions and propose for it to be used to replace commercially produced apparatuses. One specific feature relating to the operation of such heat exchangers with single-phase coolants is that the gaps in the structural members of the inter-tube space have an effect on the coefficients of heat transfer on the oil side.
Curves of the oil outlet temperature of the MP-37 oil cooler as a function of the water inlet temperature at the Verkhnetagil district power station. (1) commercially produced oil cooler; (2) modernized oil cooler
Experience gained from modernization of oil coolers for 800-MW turbines has shown that stainless tubes should be used in oil coolers for bringing these apparatuses into compliance with the modern requirements for environmental safety of thermal power stations. In this case, in order to compensate for a lower heat conductivity coefficient of tubes (as compared with that in case of using tubes made of nonferrous alloys), it is recommended that smooth tubes be replaced by twisted profiled tubes (TPTs), which can be made of smooth ones by rolling a helical groove on their external surface. The corresponding protrusions will in this case appear on the inner surface of these tubes (see Fig. 1). The use of TPTs in oil coolers with disk-ring partitions is quite efficient, because it results not only in a smaller pressure drop on the oil side of the apparatus (as compared with its smooth-tube version), but also in a lower temperature of oil at the outlet.
The designs of modernized oil coolers must comply with often contradictory requirements that arise during operation of a thermal power station. This produces a need to carry out calculations of different design versions of oil coolers, which can be performed using zone-to-zone methods. Calculations according to these methods have shown that the number of passes on the oil side has the greatest influence on the thermal- hydraulic characteristics of an oil cooler.
The analysis also shows that there is no sense in sealing the gap in the intermediate partition in oil coolers of “disk-ring” partitions type. The gap between the shell and annular partition, however, should be sealed, because this measure helps improve the efficiency of an oil cooler and obtain lower temperature of oil at the apparatus outlet.
The results of calculations have also shown that the effect of tube material on the oil cooler characteristics is insignificant and that tubes made of Grade 08Cr18Ni10Ti stainless steel are more reliable under specific operating conditions. Changing the diameter of tubes (from 16 to 19 mm) results in that the heat- transfer area becomes 15—18% smaller, and it is hardly advisable. The transverse pitch between the tubes in the bundle is taken equal to 21 mm in the modernized version, which allowed us to obtain the required level of hydraulic resistance on the oil side.
Fig. 6 shows the results obtained from tests of the pilot MB- 270-330 oil coolers at the Perm district power station. It can be seen from the picture that the new oil cooler has better indicators compared with those of the commercially produced M-540 apparatus, which is manifested in a deeper cooling of oil (by 3°C).
Results obtained from comparative tests of oil coolers. (□) Serially produced oil cooler and (▧) modernized oil cooler; t1o and t2o are the temperatures of oil at the inlet to the oil cooler and at the outlet from it, and t1w is the temperature of water at the oil cooler inlet
Fig. 6 also shows the results obtained from tests of the MB-125-165 oil cooler that was developed by the authors of this paper and is installed in T-250/300-240 turbines of Ural Turbine Works production instead of the M-240 oil coolers with wire-loop finning that have worked out their service life. The main design and engineering solutions implemented in the MB-270-330 apparatus were used in the course of developing the MB-125-165 oil cooler. It follows from Figure 6 that the oil outlet temperature of the MB-125-165 cooler is 5°C lower than that in the commercially produced M-240 oil cooler. Fifteen MB-125-165 oil coolers have now been manufactured and installed at Russian thermal power stations.
In the following we discuss new designs for other heat exchangers that have been developed and carried out using the above proposed approaches and are well to be recommended for prolonged operation in thermal power plants. The scientific justification for these developments employs a set of theoretical and test stand (physical) studies.
The major problem in modernizing the PSV-315-14-23 hot water heater of KhTZ production K-300-240 turbine at the district heating system of the Reftinskaya State regional electric power plant (GRES) was to develop a design for the preheater which would compensate for the large thermal stresses which develop during startup and shutdown of the preheater while retaining the thermal capacity of the system. Here it was necessary to take into account the fact that during operation under the conditions at the Reftinskaya GRES the main water preheaters essentially operate without being contaminated and they are not cleaned.
This problem is solved by choosing a tube system for the heater (Fig. 7) made of 16/14 mm U-shaped tubes (material CuNi5Fe). The positions of the intermediate partitions are optimized and the bends in the pipes are wound with damping belts in order to reduce the danger of vibrational damage to the tube system. The design of the steam guard shield is changed; this increased the operational reliability of the peripheral sequences of tubes. The casing of the tube system of the heater has vertical and intermediate horizontal baffles whose design facilitates a reduction in the steam return flows alongside the tube bundle, thereby raising its thermal efficiency. The heat exchange surface of the preheater is increased to 335 m2. A special method is used to fix the tubes to a tube sheet with orifices flared in advance (see Fig. 7).
The major problem in modernizing a VVT-100 heat exchanger intended for distillate cooling in the water cooling system for the generators of the LMZ K-800-240 turbines at the Perm GRES (Fig.8) was to increase the repairability of the heat exchanger while retaining its reliability and thermal capacity. The problem is stated this way because, after disassembly, repair, and reassembly, the gland seal in the VVT-100 heat exchanger is often not leakproof and, with time, the seals on the annular tube partitions are destroyed.
Modernized tube system for a type PSV-315M-14-23 hot water heater: 1 — tube sheet; 2, 3 — disk partitions; 4 — U- shaped heat exchanger tubes; 5, 6 — vertical baffles; 7 — frame tubes; 8 — steam guard shield; 9 — damping belt; 10 — cotter pin
All components of the tube system of the modernized VVT-100M heat exchanger (profiled 16/14.4-mm-diam tubes, tube sheets, special casings) were made of corrosion resistant 08Cr18Ni10Ti (12Cr18Ni10Ti) alloy. The positions of the “disk-and-ring” partitions were determined taking the vibration characteristics of the tubes into account. Special casings which provided additional paths for the cooled distillate in the space between the tubes of the heat exchanger were installed in the upper and lower parts of the tube system to increase the heat transfer efficiency and segmented seals made of teflon tape were installed in the annular partitions to eliminate leakages alongside the tube bundle. A special method with pre-flaring of the orifices was used to fix the tubes in the tube sheets. The upper tube sheet has specially developed gland seals which make it possible to maintain a pressure of up to 2.5 MPa (25 kgf/cm2) in tube space. This joint ensures leakproofing of the tube space of the heat exchanger when it is repeatedly assembled and disassembled (see Fig. 8.)
Modernized VVT-100M heat exchanger: 1 — shell; 2 — lower water chamber; 3 — upper water chamber; 4 — tube system; 5 — silicone ring; 6 — teflon seal
The upper water chamber of the heat exchanger has a removable lid for inspection and cleaning of the tubes without breaking the leaktightness of the tube space. For protection from corrosion the inner surfaces of the water chambers are coated with a special enamel.
The main task in modernizing the MB-190-250 oil cooler for the lubrication system of the KhTZ K-500-240 turbine at the Reftinskaya GRES (replacing a worn out unit) was to increase its repairability and reliability while retaining its thermal capacity.
The overall and connector sizes for the MB-190M-250 oil cooler (Fig. 9) are the same as those for the commercially manufactured MB-190-250 oil coolers. In the modernized oil cooler the major components of the water chambers, tube sheets and 16/14.4-mm-diam heat exchanger tubes are made of corrosion resistant 08Cr18Ni10Ti (12Cr18Ni10Ti) alloy. A special method was used for fixing the tubes to the tube sheets (see Fig. 9.) The system for arranging the “disk-and-ring” partitions and the configuration of the tube bundles were optimized taking the task of modernizing the oil cooler into account. (Plain tubes are installed in the oil cooler, since profiled tubes would lead to an unacceptable increase in the hydraulic resistance on the water side and to a limitation on the flow rate of cooling water in the unit.) In addition, special casings are installed in the upper and lower parts of the tube system to provide additional paths for the cooled oil in the tube space, while segmented seals made of teflon tape are mounted in the annular partitions in order to eliminate leakage along the tube bundle. The oil cooler was made more repairable by changing the design configuration for compensating the temperature expansion of the tube system relative to the shell. For this, the upper tube sheet has an elastic diaphragm (membrane) junction with the shell, while the upper water chamber has a removable cover for inspection and cleaning of the oil cooler tubes without breaking the leaktightness of the oil space. The surfaces of the covers and bottoms that are in contact with the cooling water are coated with a special anticorrosion coating.
Reconstruction of the main ЀР-3-25/75 ejectors coolers of the KhTZ K-300-240 turbine and the ЀР-3-50/150 ejectors coolers of the KhTZ K-500-240 turbine at the Reftinskaya GRЀS was carried out in connection with the end of the coolers’ service lives and was related to a need to replace tubes made of CuNi5Fe alloy with tubes made of 08Cr18Ni10Ti stainless steel. The arrangement system for the tube partitions in the steam space of the cooler was optimized taking the change in the tube rigidity into account and the heat exchanger surface was increased as well. When the tubes were flared in the tube sheets a special method was used with the orifices pre-flaring. Profiled heat exchanger tubes were installed in the cooler.
The aim in reconstructing the tube bundles for the fire resistant liquid coolers in the regulatory system for LMZ K-300-240 turbines (Sredneural’sk GRES, Konakovo GRES — horizontal tube bundles) and LMZ K-800-240 turbines (Surgut GRES-2, Nizhnevartovsk GRES, Berezovskii GRES — vertical tube bundles) was to replace tube bundles that had gone past their service lifetimes, as well as to increase their thermal capacity and reliability.
The basic components of the cooler (profiled 16/14.4- mm-diam tubes, tube sheets, special casing) were made of corrosion resistant 08Cr18Ni10Ti (12Cr18Ni10Ti) steel. The configuration of the tube bundle is optimized on the basis of a set of thermal-hydraulic calculations. The thermal capacity of the cooler was raised by increasing its heat exchange surface beyond that of the commercial units. The tubes were flared in the tube sheets using special fixing method with the pre-flared orifices in the tube sheet.
Modernized MB-190M-250 oil cooler: 1 — shell; 2 — lower water chamber; 3 — upper water chamber; 4 — tube system; 5 — diaphragm (membrane); 6 — oil resistant gasket; 7 — silicone ring
Leakage of the fire resistant liquid off the tube bundle was eliminated by installing a special casing at the annular partitions which ensured that it was joined in a leakproof seal to the annular partitions to prevent the “idle” oil leakage.
Modernization was also carried out for water-to-water heat exchangers of OB-700-1 type deployed in a technological subsystem of Perm state district power station. Heat exchangers of OB-700-1 type are vertical shell-and-tube apparatuses of integral design and this considerably reduces the opportunities of diagnostics, maintenance and repair to be performed by operational personnel of state district power station.
Heat exchanger OB-700-1 is installed at Perm state district power station in the closed system of oil ( or fire resistant liquid) cooling for K-800-240 turbines, so for the river Kama protection against oil pollution there is accomplished two-loop system of oil cooling. On passing through the oil coolers the cooling water is directed to two OB-700-1 heat exchangers where it is cooled by circulation water flowing inside the tubes.
The analysis of operation regimes of said heat exchangers showed that during 20 years they were operated with smaller than recommended (nominal) rates of water flow. Because of strong pollution of outside tube surface and significant number of gagged tubes (up to 50%) the apparatuses have high intertube and inner tube hydraulic resistance. Besides significant corrosion deterioration is observed on tube plates.
According to technical project of Perm state district power station it was necessary when performing OB-700-1 modernization to meet the following basic requirements:
to reduce surface pollution and lower its affect on thermal efficiency of heat exchangers;
tube bundle should be disassembling to make it possible to disunite it from the shell provided that all the external connecting dimensions are left without changes;
to raise the heat exchangers reliability and reduce corrosive affect of the cooling mediums;
to provide an opportunity of hydraulic test of tube system to be carried out without removing it from the shell;
to optimize heat exchangers thermal and hydraulic characteristics in order to minimize circulating water consumption.
To meet these challenges during modernization lots of optimizing calculations were carried out with reference to heat exchangers operating conditions at Perm state district power station.
At the concept phase of modernization project the calculations were performed of thermal, hydraulic and reliability characteristics for OB-700-1 heat exchangers. For all the apparatus elements operating under pressure 0.5 MPa durability and reliability characteristics were calculated according to actual normative and technical documentation. On the basis of thermal and hydraulic characteristics optimizing calculations and in order to reduce surface pollution an effective cross section of intertube space was increased due to tube bundle configuration change and to employing of intermediate partitions of «disk-and-ring» type. Also heat transfer surface was reduced from 896 m2 to 480 m2, demanded operational characteristics being unchanged. Tube system vibration characteristics calculation permitted to choose a number of its constructive parameters such as thickness of intermediate tube partitions, technological annular clearance between tube and tube sheet orifice, distance between intermediate tube sheets.
According to the design project developed by authors the tube system of modernized heat exchangers OB-700M (Fig. 10) employs intermediate tube partitions of «disk-and-ring» type, welded to frame tubes of tube bundle. Absence of leakage between intermediate tube partitions and cylindrical shell is provided by means of special sealing (Fig. 10).
During modernization of OB-700-1 type heat exchangers for Perm state district power station the following technical conceptions have also been accomplished:
connecting and overall dimensions of the new (modernized) tube system make possible its installation into the existing cooler shell;
tubes are made of copper-nickel alloy CuNi5Fe possessing high corrosion resistance. The anticorrosive covering is rendered on tube sheets and on internal surfaces of water chambers to increase their corrosion stability;
for increasing of tube and tube sheet jointing tightness a special way is used employing reliefs rolled on a tube plate aperture surface;
inward flange (item 5 in Fig. 10) is used which allows after bottom water chamber removal to carry out hydraulic test without tube system lifting out of the shell;
for bottom water chamber as well as for inward flange sealing a silicon cord is employed enabling repeated disassembly of the chamber without replacement of sealing material;
hatches of 500 mm in diameter are made in the top water chamber for tube sheets survey and cleaning.
Heat exchanger OB-7OOM. 1 — tube system assembly, 2 — intermediate tube partition of «ring» type, 3 — intermediate tube partition of «disk» type, 4 — special sealing, 5 — inward flange
According to the described concept in 2005 modernization and advanced development were performed of two samples of OB-700M type heat exchangers. After the modernization some starting-up and adjustment tests on OB-700M heat exchangers were carried out at Perm state district power station. For this purpose the heat exchanger was equipped with measuring devices permitting complete thermal balance definition. During the tests the temperatures and flow rates were measured for cooling and cooled water as well. The maximal divergence of heat flow values did not exceed 9.2%.
Test results showed that modernized heat exchangers are capable to function effectively, i.e. to cool the water to temperature demanded by technological process.
The measured values of heat exchanging mediums temperatures are close to designed ones. Thus, for example, the difference between designed and measured water temperature does not exceed 0.6°C.
The article presents the results of selection and justification of a number of technical solutions for power station heat exchanger modernization. The calculation technique is laid down for oil coolers with TPTs. The results are shown of preproduction tests for the new heat exchangers as well as a number of advanced and refined designs of oil coolers and water heaters.
The heat exchangers of steam turbines modernized according to described concepts have undergone industrial tests and are in successful use at various thermal electric power plants of Russia. Prolonged (up to 20 years) operating experience for more than 500 developed and manufactured apparatuses has confirmed the validity of the technical solutions, as well as high efficiency and operational reliability of these heat exchangers.
TPT — twisted profile tube
δ — wall thickness
h — depth
s — pitch between the neighboring grooves
z — number of profiling threads
t — thread rolling pitch
dcc — circumferential diameter
δ1, δ2, δ3 — the gaps between the shell and annular partition plate, in the orifices of the annular and disc partition plates correspondingly
Go — oil flow rate through the tube bundle
t1o and t2o — oil temperatures at the inlet and outlet of the oil cooler
t1w — temperature of water at the oil cooler inlet
Pesticides management options for control of invertebrate pests in many parts of the world [1, 2]. Despite an increase in the use of pesticides, crop losses due to pests have remained largely unchanged for 30–40 years [3]. Beyond the target pests, broad-spectrum pesticides may affect non-target invertebrate species [4], including causing reductions in natural enemy population abundance and activity [5, 6], and competition between pest species [7]. Assays of invertebrates against weathered residues have shown the persistence of pesticides might play an important part in their negative impacts on natural enemies in the field [8].
A potential outcome of frequent broad-spectrum pesticide use is the emergence of pests not controlled by the pesticides but benefiting from reduced mortality from natural enemies and competitive release, commonly known as secondary pests [9, 10, 11]. Secondary pest outbreaks are challenging as they may also be caused by other mechanisms, which inherently make it difficult to determine how frequently pesticide use results in this outcome [10]. In cotton fields, it was estimated that 20% of late-season pesticide costs were attributable to secondary pest outbreaks caused by early-season pesticide applications for
One standardized approach for assessing non-target impacts of pesticides is the International Organization for Biological and Integrated Control—Pesticides and Beneficial Organisms (IOBC) rating system [12, 13, 14]. Subsequently, more bioassays under field conditions are needed to incorporate the dynamic interaction between pest populations and their natural enemy communities [15] and the environmental context at the time of application [16, 17, 18].
In Australian broad-acre grains the pest management practitioners are primarily concerned with pesticide efficacy, crop phytotoxicity, and cost; seldom are broader impacts of pesticides included in decision-making [19, 20, 21]. Chlorpyrifos is applied for the control of pests such as earwigs, isopods, and millipedes (Portuguese millipede,
The indirect effects of pesticides on natural enemies have not been studied as extensively compared to direct effects, this chapter presents the indirect effects of pesticides that have primarily involved evaluating fecundity and longevity [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35].
Prey consumption is the most important to successfully integrating natural enemies with pesticides and prevents indirect consequences on population dynamics [36, 37].
Some factors affiliated with natural enemies that may influence the indirect effects of pesticides include natural enemy age, type of natural enemy, life stages exposed to pesticides, and sex [38, 39]. Indirect affect may be related to residues remaining after a foliar application [40, 41]. Residues remaining after application may indirectly affect parasitoids by inhibiting adult emergence [42].
Natural enemies, indirectly affected by feeding on contaminated honeydew excreted by phloem-feeding insect prey [43, 44]. Certain pesticides may also exhibit repellent activity [45, 46] or alter host plant physiology [47, 48] indirectly affecting the ability of natural enemies to regulate existing arthropod pest populations [49].
Applied as granules have been promoted to be relatively non-toxic to natural enemies [49, 50, 51]. However, insecticides as systemic effect exhibit indirect effects against natural enemies via several mechanisms of prey floral parts contaminated with the active ingredients [52, 53, 54]. Systemic insecticides may indirectly influence natural enemies if the mortality of prey populations is high [55, 56].
Natural enemies decrease the populations during starvation or dispersal [55, 57, 58, 59]. This effect depends on the foraging efficiency of the specific natural enemy. Decrease quantity or density of available prey or decrease their quality such that they are not acceptable as a food source, indirectly affected on larvae and adults or female parasitoids not lay eggs. Reproduction, foraging, fecundity, and longevity [33].
The active ingredient of systemic insecticide is distributed into flower parts indirectly impact natural enemies that feed on plant pollen or nectar such as minute pirate bug,
Insect growth regulators are active directly on immature stages of some insect pests, there are three types of insect growth regulators: juvenile hormone mimics, chitin synthesis inhibitors, and ecdysone antagonists [64, 65, 66, 67, 68, 69].
Pyriproxyfen, a juvenile hormone mimic is not indirect harmful effects against adult female oviposition and egg viability of green lacewing,
Fifth instars of
Kinoprene is indirectly harmful against natural enemies by inhibiting adult emergence of,
It is a juvenile hormone analog [80, 81] that has shown to be indirectly harmful to some natural enemies. It is delay development time from of pupae and adult of
It is a growth regulator that disrupts molting, it is affecting cuticle sclerotization during increasing cuticle stiffness [65], and exhibits indirect effects on the reproduction of
It is a chitin synthesis inhibitor [65], less indirect impact against natural enemies, both parasitoids and predators [87].
Exposure to it decreased female longevity and reduced the parasitization rate of,
It is a chitin synthesis inhibitor [66, 90], sterilizes certain natural enemies [91], reduces the number of progeny per female and sex ratios [73]. Feeding on it decreases female fertility and fecundity, and sterilized the males of the predatory coccinellid,
Indirect effects on natural enemies due to the volatility of the compound as it is known to be volatile and display vapor activity on some insect pests [98].
It is an ecdysone antagonist [72, 97, 98, 99, 100, 101], indirect effects against natural enemies [102]. It inhibits oviposition of the green lacewing,
First larvae of
It is include flonicamid and pymetrozine, inhibits feeding activity of piercing-sucking insects after initial insertion of their stylets into plant tissues and interfere with neural regulation of fluid intake through the mouthparts resulting in starvation [102, 109, 110, 111, 112]. Flonicamid and pymetrozine, did not affect the development time, fertility, and parasitism of natural enemies,
Entomopathogenic fungi and bacteria are, in general, not indirectly harmful to natural enemies, this may vary depending on concentration, natural enemy type, life stage exposed, the timing of application, and environmental conditions [114, 115].
Indirect effect not be associated with entomopathogenic fungi or bacteria [116].
Natural enemies ingest fungal spores during grooming or feeding on contaminated hosts [89]; also, indirect effects depend on the concentration of spores [118]. Entomopathogenic fungi indirectly affect some natural enemies during feeding on prey that have been sprayed. Larvae of,
Spinosad has been demonstrated to be indirectly harmful to a variety of predatory insects such as,
It is like other pesticides, demonstrate variability in regards to any indirect effects against natural enemies depending on the type of miticide and predatory mite species [127]. It did not affect
Exposure to bifenazate did not reduce fecundity, longevity, or prey consumption of
It is considered low harmful to natural enemies comparing with insecticides and miticides [134]. Mancozeb was negatively affected against fecundity and reproduction of,
The methodology evaluates the indirect effects of pesticides on natural enemies that may influence the results obtained [136, 137, 138, 139, 140, 141, 142, 143, 144]. The indirect effects of pesticides against natural enemies not necessarily are affiliated with the active ingredient [136, [141, 142, 143, 144]. It is can be formulations as emulsifiable concentrates (EC) and soluble powders (SP) contain additives as adjuvants, surfactants, solvents, or carriers that are indirectly harmful to natural enemies [145].
This chapter has demonstrated the feasibility of combining or integrating natural enemies with certain pesticides including systemic insecticides, insect growth regulators, selective feeding blockers, microbials, miticides, and fungicides. There are three primary means by which natural enemies integrated with pesticides including pesticide selection, spatial separation of natural enemies and pesticides, and temporal discontinuity between natural enemies and pesticides [114]. Indirect effects are evaluated to determine if pesticides are compatible with natural enemies [29]. Indirect effects depending on concentration, natural enemy species, pesticide exposure time, developmental life stage(s) evaluated, and the influence of residues and repellency [50].
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On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. 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We examine first the routes of exposure of bees to agrochemicals used for crop protection and their application to crops, fate and contamination of water and plants around the fields. Most of the time, the exposure of bees to pesticides is through ingestion of residues found in the pollen and nectar of plants and in water. Honey bees are also exposed to pesticides used for the treatment of Varroa and other parasites. The basic concepts about the toxicity of the different kinds of pesticides are explained next. Various degrees of toxicity are found among agrochemicals, and emphasis is given to the classic tenet of toxicology, “the dose makes the poison,” and its modern version “the dose and the time of exposure makes the poison.” These two factors, dose and time, help us understand the severity of the impacts that pesticides may have on bees and their risk, which are analysed in the third section. Sublethal effects are also considered. The final section is devoted to some practical advice for avoiding adverse impacts of pesticides in beekeeping.",book:{id:"5163",slug:"beekeeping-and-bee-conservation-advances-in-research",title:"Beekeeping and Bee Conservation",fullTitle:"Beekeeping and Bee Conservation - Advances in Research"},signatures:"Francisco Sanchez-Bayo and Koichi Goka",authors:[{id:"74970",title:"Dr.",name:"Francisco",middleName:null,surname:"Sánchez-Bayo",slug:"francisco-sanchez-bayo",fullName:"Francisco Sánchez-Bayo"},{id:"192045",title:"Dr.",name:"Koichi",middleName:null,surname:"Goka",slug:"koichi-goka",fullName:"Koichi Goka"}]},{id:"59212",doi:"10.5772/intechopen.73864",title:"Insect Conservation for the Twenty-First Century",slug:"insect-conservation-for-the-twenty-first-century",totalDownloads:1938,totalCrossrefCites:7,totalDimensionsCites:14,abstract:"Insects have been immensely successful as an animal group. They dominate compositional diversity of all but the saltiest and coldest parts of the planet. Yet today insects are declining at a precipitous rate. This is of great concern in terms of impoverishment of Earth, and is also dire for us. Insects contribute to the maintenance of terrestrial and freshwater systems, their service delivery and their resilience. The meteoric impact of humans is challenging this dominance, yet so few people realize that the very fabric of life on which they depend is being unraveled at an alarming rate. Action is required, as are new perspectives, if we are to maintain insect diversity and services through the twenty-first century. Here, we review how we should view and act to have more effective insect diversity conservation based on six themes: (1) philosophy (establishing the ethical foundation), (2) research (the finding out), (3) policy (the framework for action), (4) psychology (understanding how to engage humans in insect conservation action), (5) practice (implementation of action), and (6) validation (establishing how well we are doing at conserving insects). We then overview some emergent challenges and solutions at both the species and landscape operational levels in agricultural, forestry, and urban environments.",book:{id:"6619",slug:"insect-science-diversity-conservation-and-nutrition",title:"Insect Science",fullTitle:"Insect Science-Diversity, Conservation and Nutrition"},signatures:"Michael J. Samways",authors:[{id:"233323",title:"Distinguished Prof.",name:"Michael",middleName:null,surname:"Samways",slug:"michael-samways",fullName:"Michael Samways"}]},{id:"50307",doi:"10.5772/62654",title:"From Extraction to Meliponiculture: A Case Study of the Management of Stingless Bees in the West-Central Region of Mexico",slug:"from-extraction-to-meliponiculture-a-case-study-of-the-management-of-stingless-bees-in-the-west-cent",totalDownloads:2729,totalCrossrefCites:5,totalDimensionsCites:9,abstract:"Currently, stingless bees' populations are declining due to environmental degradation. In this context, the authors have developed a research project in the central-western region of Mexico with the goal to generate strategies for conservation and sustainable management of stingless bees. The chapter aims to present the process of this investigation and its main results in terms of a) local knowledge and management strategies of stingless bees, and b) the social process of technological appropriation of meliponiculture by beekeepers. We recognized specific knowledge on the biology and ecology of stingless bees that result in a system for identifying species and management strategies of wild populations of these bees based on the extraction of nests. The implementation of an innovative productive activity based on the principles of meliponiculture and current techniques has been well received by producers, which has led to the formation of the Meliponicultores Michoacanos del Balsas Association, which grows five species of stingless bees. The research suggests that conservation associated with the use of bees (integral meliponiculture) can be enhanced in the region. Faced with the loss of biodiversity and environmental crisis, it is essential to maintain and enhance local knowledge of stingless bees and management practices. This represents an alternative to develop management schemes that allow the raising and breeding of these bees, while its products are obtained.",book:{id:"5163",slug:"beekeeping-and-bee-conservation-advances-in-research",title:"Beekeeping and Bee Conservation",fullTitle:"Beekeeping and Bee Conservation - Advances in Research"},signatures:"Alejandro Reyes-González, Andrés Camou-Guerrero and Salvador\nGómez-Arreola",authors:[{id:"179951",title:"Dr.",name:"Andres",middleName:null,surname:"Camou-Guerrero",slug:"andres-camou-guerrero",fullName:"Andres Camou-Guerrero"},{id:"185413",title:"MSc.",name:"Alejandro",middleName:null,surname:"Reyes-González",slug:"alejandro-reyes-gonzalez",fullName:"Alejandro Reyes-González"},{id:"192049",title:"Dr.",name:"Salvador",middleName:null,surname:"Gómez-Arreola",slug:"salvador-gomez-arreola",fullName:"Salvador Gómez-Arreola"}]},{id:"50170",doi:"10.5772/62395",title:"A Comprehensive Characterization of the Honeybees in Siberia (Russia)",slug:"a-comprehensive-characterization-of-the-honeybees-in-siberia-russia-",totalDownloads:2270,totalCrossrefCites:4,totalDimensionsCites:8,abstract:"A comprehensive study of some populations of honeybee (332 colonies) in Siberia (Tomsk region, Krasnoyarsk Krai (Yenisei population), Altai) using morphometric and molecular genetic methods was conducted. Infestation of bees (132 colonies) by Nosema has also been studied. Three variants of the COI-COII mtDNA locus were registered: PQQ, PQQQ (typical for Apis m. mellifera), and Q (specific for southern races). It was established that 64% of bee colonies from the Tomsk region and all colonies studied from the Krasnoyarsk and the Altai territories originate from Apis m. mellifera on the maternal line. According to the morphometric study, the majority of bee colonies of the Tomsk region are hybrids; in some colonies the mismatch of morphometric and mtDNA data was observed. Moreover, the majority of bee colonies infected by Nosema were hybrids. Yenisei population may be considered as a unique Apis m. mellifera population. Microsatellite analysis (loci А008, Ap049, AC117, AC216, Ap243, H110, A024, A113) showed the specific distribution of genotypes and alleles for some loci in the bees, which differ by geographical location. Loci A024 and Ap049 are of considerable interest for further study as candidate markers for differentiation of subspecies; locus A008 can be considered informative for determining of different ecotypes of Apis m. mellifera.",book:{id:"5163",slug:"beekeeping-and-bee-conservation-advances-in-research",title:"Beekeeping and Bee Conservation",fullTitle:"Beekeeping and Bee Conservation - Advances in Research"},signatures:"Nadezhda V. Ostroverkhova, Olga L. Konusova, Aksana N. Kucher\nand Igor V. Sharakhov",authors:[{id:"180112",title:"Ph.D.",name:"Nadezhda",middleName:null,surname:"Ostroverkhova",slug:"nadezhda-ostroverkhova",fullName:"Nadezhda Ostroverkhova"},{id:"180249",title:"Ms.",name:"Olga",middleName:null,surname:"Konusova",slug:"olga-konusova",fullName:"Olga Konusova"},{id:"180342",title:"Prof.",name:"Aksana",middleName:null,surname:"Kucher",slug:"aksana-kucher",fullName:"Aksana Kucher"},{id:"180343",title:"Prof.",name:"Igor",middleName:null,surname:"Sharakhov",slug:"igor-sharakhov",fullName:"Igor Sharakhov"}]},{id:"50683",doi:"10.5772/63145",title:"Advances in Pharmacological Activities and Chemical Composition of Propolis Produced in Americas",slug:"advances-in-pharmacological-activities-and-chemical-composition-of-propolis-produced-in-americas",totalDownloads:2550,totalCrossrefCites:2,totalDimensionsCites:8,abstract:"Propolis is a resinous material produced by bees from the selective collection of plant exudates that are subsequently mixed with beeswax and salivary bee secretions. Propolis has been used in folk medicine, and certainly, several studies have validated its biological properties. The chemical composition and pharmacological activities of propolis collected through North (including Central America and Caribbean) and South America have been studied in the last years, and several papers have reported differences and similarities among the analysed geographical samples. Propolis has been classified according to its aspect and plant source; however, the ecological diversity present along the Americas provides a plethora of botanical resins. Herein, we summarize and discuss most of the studies performed at present on this profitable product for apiculture, attempting to compare the bioactivity, phytochemical diversity and botanical sources of honeybee propolis produced in Americas.",book:{id:"5163",slug:"beekeeping-and-bee-conservation-advances-in-research",title:"Beekeeping and Bee Conservation",fullTitle:"Beekeeping and Bee Conservation - Advances in Research"},signatures:"Efrain Alday, Moisés Navarro-Navarro, Adriana Garibay-Escobar,\nRamón Robles-Zepeda, Javier Hernandez and Carlos Velazquez",authors:[{id:"96966",title:"MSc.",name:"Moises",middleName:null,surname:"Navarro-Navarro",slug:"moises-navarro-navarro",fullName:"Moises Navarro-Navarro"},{id:"180409",title:"Dr.",name:"Carlos",middleName:null,surname:"Velazquez",slug:"carlos-velazquez",fullName:"Carlos Velazquez"},{id:"186351",title:"Dr.",name:"Ramón",middleName:null,surname:"Robles-Zepeda",slug:"ramon-robles-zepeda",fullName:"Ramón Robles-Zepeda"},{id:"186352",title:"MSc.",name:"Efrain",middleName:null,surname:"Alday",slug:"efrain-alday",fullName:"Efrain Alday"},{id:"186353",title:"Dr.",name:"Javier",middleName:null,surname:"Hernandez",slug:"javier-hernandez",fullName:"Javier Hernandez"},{id:"189161",title:"Dr.",name:"Adriana",middleName:null,surname:"Garibay-Escobar",slug:"adriana-garibay-escobar",fullName:"Adriana Garibay-Escobar"}]}],mostDownloadedChaptersLast30Days:[{id:"50170",title:"A Comprehensive Characterization of the Honeybees in Siberia (Russia)",slug:"a-comprehensive-characterization-of-the-honeybees-in-siberia-russia-",totalDownloads:2270,totalCrossrefCites:4,totalDimensionsCites:8,abstract:"A comprehensive study of some populations of honeybee (332 colonies) in Siberia (Tomsk region, Krasnoyarsk Krai (Yenisei population), Altai) using morphometric and molecular genetic methods was conducted. Infestation of bees (132 colonies) by Nosema has also been studied. Three variants of the COI-COII mtDNA locus were registered: PQQ, PQQQ (typical for Apis m. mellifera), and Q (specific for southern races). It was established that 64% of bee colonies from the Tomsk region and all colonies studied from the Krasnoyarsk and the Altai territories originate from Apis m. mellifera on the maternal line. According to the morphometric study, the majority of bee colonies of the Tomsk region are hybrids; in some colonies the mismatch of morphometric and mtDNA data was observed. Moreover, the majority of bee colonies infected by Nosema were hybrids. Yenisei population may be considered as a unique Apis m. mellifera population. Microsatellite analysis (loci А008, Ap049, AC117, AC216, Ap243, H110, A024, A113) showed the specific distribution of genotypes and alleles for some loci in the bees, which differ by geographical location. Loci A024 and Ap049 are of considerable interest for further study as candidate markers for differentiation of subspecies; locus A008 can be considered informative for determining of different ecotypes of Apis m. mellifera.",book:{id:"5163",slug:"beekeeping-and-bee-conservation-advances-in-research",title:"Beekeeping and Bee Conservation",fullTitle:"Beekeeping and Bee Conservation - Advances in Research"},signatures:"Nadezhda V. Ostroverkhova, Olga L. Konusova, Aksana N. Kucher\nand Igor V. Sharakhov",authors:[{id:"180112",title:"Ph.D.",name:"Nadezhda",middleName:null,surname:"Ostroverkhova",slug:"nadezhda-ostroverkhova",fullName:"Nadezhda Ostroverkhova"},{id:"180249",title:"Ms.",name:"Olga",middleName:null,surname:"Konusova",slug:"olga-konusova",fullName:"Olga Konusova"},{id:"180342",title:"Prof.",name:"Aksana",middleName:null,surname:"Kucher",slug:"aksana-kucher",fullName:"Aksana Kucher"},{id:"180343",title:"Prof.",name:"Igor",middleName:null,surname:"Sharakhov",slug:"igor-sharakhov",fullName:"Igor Sharakhov"}]},{id:"70501",title:"Southeast Asian Meliponiculture for Sustainable Livelihood",slug:"southeast-asian-meliponiculture-for-sustainable-livelihood",totalDownloads:1233,totalCrossrefCites:2,totalDimensionsCites:5,abstract:"Stingless bees (Apidae: Meliponini) are one of the most important pollinators of native plants and economic crops in tropical and subtropical parts of the world. They not only establish large perennial colonies with complex social organization but also have a diverse nesting biology. The economic utilization of a total of 60 stingless bee species in Asia has been reported. The current status of meliponiculture in Southeast Asia is mainly focused on pollination utilization and honey and propolis production. This chapter shows that small-scale beekeeping of stingless bees, which is suitable for the flowering pattern in the tropics, is one of the best potential alternative opportunities. The cost-effectiveness analysis based on production yield, investment cost, and profit-return rate is reviewed. Finally, a sustainable utilization of stingless bees is considered to be an enhancer of pollination services both in an agricultural crop and natural ecosystem.",book:{id:"8929",slug:"modern-beekeeping-bases-for-sustainable-production",title:"Modern Beekeeping",fullTitle:"Modern Beekeeping - Bases for Sustainable Production"},signatures:"Atsalek Rattanawannee and Orawan Duangphakdee",authors:[{id:"283087",title:"Ph.D.",name:"Atsalek",middleName:null,surname:"Rattanawannee",slug:"atsalek-rattanawannee",fullName:"Atsalek Rattanawannee"},{id:"306411",title:"Dr.",name:"Orawan",middleName:null,surname:"Duangphakdee",slug:"orawan-duangphakdee",fullName:"Orawan Duangphakdee"}]},{id:"50073",title:"Impacts of Pesticides on Honey Bees",slug:"impacts-of-pesticides-on-honey-bees",totalDownloads:3361,totalCrossrefCites:18,totalDimensionsCites:39,abstract:"This chapter focuses on the detrimental effects that pesticides have on managed honey bee colonies and their productivity. We examine first the routes of exposure of bees to agrochemicals used for crop protection and their application to crops, fate and contamination of water and plants around the fields. Most of the time, the exposure of bees to pesticides is through ingestion of residues found in the pollen and nectar of plants and in water. Honey bees are also exposed to pesticides used for the treatment of Varroa and other parasites. The basic concepts about the toxicity of the different kinds of pesticides are explained next. Various degrees of toxicity are found among agrochemicals, and emphasis is given to the classic tenet of toxicology, “the dose makes the poison,” and its modern version “the dose and the time of exposure makes the poison.” These two factors, dose and time, help us understand the severity of the impacts that pesticides may have on bees and their risk, which are analysed in the third section. Sublethal effects are also considered. The final section is devoted to some practical advice for avoiding adverse impacts of pesticides in beekeeping.",book:{id:"5163",slug:"beekeeping-and-bee-conservation-advances-in-research",title:"Beekeeping and Bee Conservation",fullTitle:"Beekeeping and Bee Conservation - Advances in Research"},signatures:"Francisco Sanchez-Bayo and Koichi Goka",authors:[{id:"74970",title:"Dr.",name:"Francisco",middleName:null,surname:"Sánchez-Bayo",slug:"francisco-sanchez-bayo",fullName:"Francisco Sánchez-Bayo"},{id:"192045",title:"Dr.",name:"Koichi",middleName:null,surname:"Goka",slug:"koichi-goka",fullName:"Koichi Goka"}]},{id:"74836",title:"Chironomidae: Biology, Ecology and Systematics",slug:"chironomidae-biology-ecology-and-systematics",totalDownloads:419,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The family of Chironomidae is a group of Diptera insects belonging to the suborder of Nematocera, commonly called “non-biting midges” in the adult stage and “bloodworms” in the larval stage. The Chironomidae are often the most abundant group of macroinvertebrates, in number of species and individuals, encountered in all aquatic environments of freshwater, brackish, terrestrial and even the sea. Likewise, Chironomidae occur in all the continents. The Chironomidae family is divided into 11 sub-families that have diffrent ecological statues. Despite the wealth of data on Chironomidae in the Holarctic region, other parts of the world are poorly studied and few guides to identifying Chironomidae have been produced. This chapter includes a theoretical synthesis on the Chironomidae, it deals with the Biology (life cycle and description of different stages), description of all subfamilies and the ecology of this important family of Diptera.",book:{id:"10423",slug:"the-wonders-of-diptera-characteristics-diversity-and-significance-for-the-world-s-ecosystems",title:"The Wonders of Diptera",fullTitle:"The Wonders of Diptera - Characteristics, Diversity, and Significance for the World's Ecosystems"},signatures:"Zerguine Karima",authors:[{id:"334825",title:"Dr.",name:"Karima",middleName:null,surname:"Zerguine",slug:"karima-zerguine",fullName:"Karima Zerguine"}]},{id:"75438",title:"Characteristics of Dipteran Insects",slug:"characteristics-of-dipteran-insects",totalDownloads:481,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Diptera means two wings (Di: two, pteron: wing). They have complete metamorphosis and they are holometabolous insects which means there are 4 stages (egg, larvae, pupae and adult). The name of larval stage is “maggot”. Some of the dipteran insects cause damage in agricultural production. Some are harmful for humans. Dipteran insects have two wings. Hind wings are reduced and they are called “halteres”. Function of halteres is balancing when the insects fly. Except mosquitoes, dipteran insects have sponging-sucking mouthparts. Important examples for dipteran insects are Olive fruit fly and Medfly which cause damages in agricultural production. OFF is the most destructive pest in olive growing areas and Mediterranean fruit fly cause damages in fruit production.",book:{id:"10423",slug:"the-wonders-of-diptera-characteristics-diversity-and-significance-for-the-world-s-ecosystems",title:"The Wonders of Diptera",fullTitle:"The Wonders of Diptera - Characteristics, Diversity, and Significance for the World's Ecosystems"},signatures:"Murat Helvacı",authors:[{id:"301984",title:"Ph.D.",name:"Murat",middleName:null,surname:"Helvaci",slug:"murat-helvaci",fullName:"Murat Helvaci"}]}],onlineFirstChaptersFilter:{topicId:"35",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"78491",title:"Insect Conservation and Management: A Need of the Hour",slug:"insect-conservation-and-management-a-need-of-the-hour",totalDownloads:25,totalDimensionsCites:0,doi:"10.5772/intechopen.100023",abstract:"Insects play a very vital role in divergent ecosystems and have gained great economic and medical importance as pollinators, pests, predators, parasitoids, decomposers and vectors. With the large-scale practice of synthetic pesticides, the diminishing rate of beneficial and pollinator insects is increasing rapidly. Environmental pollution, climate change, global warming, urbanization, industrialization and some natural calamities like wildfires add more fuel to the acceleration of insect decline all over the world. Alternative steps should be employed to replace the toxic pesticides and implementation of integrated pest management (IPM) should be put forward to reduce the overuse of synthetic pesticides and fertilizers, which have a great impact on beneficial insects as well as birds, aquatic organisms, and also on human health. The present study aims to create awareness among the researchers and general public by providing a brief review of insect importance, decline and conservation strategies.",book:{id:"10739",title:"Global Decline of Insects",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg"},signatures:"Muzafar Riyaz, Rauf Ahmad Shah and Soosaimanickam Maria Packiam"},{id:"80971",title:"Agricultural Intensification Causes Decline in Insect Biodiversity",slug:"agricultural-intensification-causes-decline-in-insect-biodiversity",totalDownloads:46,totalDimensionsCites:0,doi:"10.5772/intechopen.101360",abstract:"The world’s population exceeded 7 billion in late 2011 and it is expected to reach 9.3 billion by 2050. Meanwhile, demand for food is predicted to increase between 50 and 100% by 2050. To meet the food demands of the increasing population, agricultural intensification practices including growing monocultures of high-yielding crop varieties and increased applications of fertilizers and pesticides have been used to increase productivity. These practices, however, impact negatively on biodiversity of existing flora and fauna, particularly causing huge declines in insect biodiversity. This chapter reviews present state of knowledge about agricultural intensification practices and global decline of insect biodiversity (i.e., pest and beneficial insect species) in intensive agricultural system and point out the likely drivers of these declines. It concludes the review by examining sustainable agricultural intensification practices that could be used to mitigate these biodiversity declines while maintaining productivity in intensive agricultural systems.",book:{id:"10739",title:"Global Decline of Insects",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg"},signatures:"Mumuni Abudulai, Jerry Asalma Nboyine, Peter Quandahor, Ahmed Seidu and Fousséni Traore"},{id:"78872",title:"Diversity, Importance and Decline of Pollinating Insects in Present Era",slug:"diversity-importance-and-decline-of-pollinating-insects-in-present-era",totalDownloads:81,totalDimensionsCites:0,doi:"10.5772/intechopen.100316",abstract:"Pollination is a multi-million-year-old co-evolutionary process involving flowering plants and pollinators. It is one of the most important mechanisms in preservation and promotion of biodiversity as well as life on Earth. Pollinator diversity is essential for maintaining overall biological diversity in many habitats including agro-ecosystems. Pollinators are responsible for assisting reproduction in over 80% of the world’s flowering plants. In their absence, humans and wildlife would go hungry. Insects are the most efficient pollinators as they play a crucial part in pollination ecology. Pollinators and their habitats have ecological, economic, cultural and social benefits. Pollination efficiency is highly dependent on certain attributes and characteristics of pollinators such as vision, anatomy, food preferences, olfaction, behaviour and learning ability. With the rapid growth of human population, our demand for food has also risen. Our agricultural systems will need to produce more food in a sustainable manner in the future to cope with this. Pollinators play an important role in these ecosystems and will continue to do so in the future. Because pollinators are so important to agriculture, we need to learn more about which crops require specific pollinators and how to best maintain and promote both wild and controlled species. Their diversity needs protection because there are specific relationships between certain crops and pollinators. Pollinator communities are suffering as a result of man-made habitat disruptions, including severe biodiversity loss. This diversity must be protected by combining conservation measures with sustainable farming practices which could increase crop yields while protecting insect pollinator species.",book:{id:"10739",title:"Global Decline of Insects",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg"},signatures:"Navkiran Kaur and Amritpal Singh Kaleka"},{id:"80012",title:"Impacts of Organic Farming on Insects Abundance and Diversity",slug:"impacts-of-organic-farming-on-insects-abundance-and-diversity",totalDownloads:104,totalDimensionsCites:0,doi:"10.5772/intechopen.102035",abstract:"Organic farming encourages maximum utilization of the natural biological processes to manage the farm in terms of soil fertilization and pest control, which implies using none or less synthetic fertilizers, pesticides, and plant and animal growth-promoting substances. All these practices increase arthropod diversity, particularly soil-dwelling insects. Intercropping, cover crops, and hedges, which are common practices in organic fields, provide alternative habitats for arthropod communities. The refugia also provide a good source of food for pollinators in terms of pollen grains and nectar. The interactions among the different plant and animal taxa (weeds, birds, mammals) that are found in the organic farming ecosystem have a great impact on insects’ abundance and diversity. This chapter summarizes the impacts of the organic farming system on the abundance and diversity of insects. The role of organic farming in mitigating the impact of agriculture intensification, urbanization, deforestation, and climate change on global insects’ decline and diversity loss is discussed.",book:{id:"10739",title:"Global Decline of Insects",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg"},signatures:"Hamadttu Abdel Farag El-Shafie"},{id:"78945",title:"Botanical Insecticides and their Potential as Anti-Insect/Pests: Are they Successful against Insects and Pests?",slug:"botanical-insecticides-and-their-potential-as-anti-insect-pests-are-they-successful-against-insects-",totalDownloads:197,totalDimensionsCites:7,doi:"10.5772/intechopen.100418",abstract:"In low-income countries, subsistence and transitional farms frequently use botanical insecticides. The shortage or high cost of industrial pesticides also prompts their use. Botanical insecticides are also prescribed by agricultural and development programs and certain development organizations. However, since insecticidal proof of their effectiveness and protection might not be sufficient or usable, this may be called into question. While insecticidal botanicals have been extensively studied, there has yet to be a fusion that focuses especially on the domestic synthesis of biopesticides that work infield and storage effectively. In this chapter, we look at the effectiveness of botanicals (neem, garlic, and essential oil) that are used as insecticides. In addition, this chapter also focuses on research carried out on the use of these essential oils as insecticides. Processes that use variable amounts of ingredients and concentrations and ratios of active ingredients can have varying impacts on the efficacy of plant-based biological insecticides. Finally, using home-made insecticides would reduce the losses that occur during food production and enable us to use environment-friendly pest management methods.",book:{id:"10739",title:"Global Decline of Insects",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg"},signatures:"Toheed Iqbal, Nazeer Ahmed, Kiran Shahjeer, Saeed Ahmed, Khalid Awadh Al-Mutairi, Hanem Fathy Khater and Reham Fathey Ali"},{id:"79060",title:"Description of a New Species of the Genus Anagrus (Hymenoptera: Chalcidoidea: Mymaridae): A Biocontrol Agent as an Alternative to Insecticide Use",slug:"description-of-a-new-species-of-the-genus-anagrus-hymenoptera-chalcidoidea-mymaridae-a-biocontrol-ag",totalDownloads:75,totalDimensionsCites:0,doi:"10.5772/intechopen.99957",abstract:"Although insects are economically important as they produce honey, silk, act as pollinators and also play an important role in functioning of an ecosystem, yet insect population is declining very fast. One of the possible causes of insects decline is excessive use of pesticides. Control of pest with synthetic chemicals or pesticides result in several issues and complications. These chemical pesticides or insecticides can also cause toxic effects on beneficial organisms like honeybees and butterflies which are important pollinators. So, biocontrol agents can be used as best alternative to control pest without harming beneficial organism and non-target insects or other organism as majority of biocontrol agents are host specific. Biological control agents including predators and parasotoids are natural enemies of insect pests. Present chapter deals with the description and illustration of one new species Anagrus (Anagrus) sololinearis sp.nov from India. This new species belongs to genus Anagrus (Hymenoptera: Chalcidoidea: Mymaridae). Genus Anagrus is considered as one of the important and most promising biocontrol agents in insects as it is an egg parasitoid.",book:{id:"10739",title:"Global Decline of Insects",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg"},signatures:"Shireen Saleem and Shoeba Binte Anis"}],onlineFirstChaptersTotal:10},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:31,numberOfPublishedChapters:314,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:112,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:105,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:16,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:4,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:14,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"7",title:"Biomedical Engineering",doi:"10.5772/intechopen.71985",issn:"2631-5343",scope:"Biomedical Engineering is one of the fastest-growing interdisciplinary branches of science and industry. The combination of electronics and computer science with biology and medicine has improved patient diagnosis, reduced rehabilitation time, and helped to facilitate a better quality of life. Nowadays, all medical imaging devices, medical instruments, or new laboratory techniques result from the cooperation of specialists in various fields. The series of Biomedical Engineering books covers such areas of knowledge as chemistry, physics, electronics, medicine, and biology. This series is intended for doctors, engineers, and scientists involved in biomedical engineering or those wanting to start working in this field.",coverUrl:"https://cdn.intechopen.com/series/covers/7.jpg",latestPublicationDate:"June 10th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:12,editor:{id:"50150",title:"Prof.",name:"Robert",middleName:null,surname:"Koprowski",slug:"robert-koprowski",fullName:"Robert Koprowski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTYNQA4/Profile_Picture_1630478535317",biography:"Robert Koprowski, MD (1997), PhD (2003), Habilitation (2015), is an employee of the University of Silesia, Poland, Institute of Computer Science, Department of Biomedical Computer Systems. For 20 years, he has studied the analysis and processing of biomedical images, emphasizing the full automation of measurement for a large inter-individual variability of patients. Dr. Koprowski has authored more than a hundred research papers with dozens in impact factor (IF) journals and has authored or co-authored six books. Additionally, he is the author of several national and international patents in the field of biomedical devices and imaging. 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His research interests are focused on modern imaging methods used in medicine and pharmacy, including in particular hyperspectral imaging, dynamic thermovision analysis, high-resolution ultrasound, as well as other techniques such as EPR, NMR and hemispheric directional reflectance. Author of over 100 scientific works, patents and industrial designs. Expert of the Polish National Center for Research and Development, Member of the Investment Committee in the Bridge Alfa NCBiR program, expert of the Polish Ministry of Funds and Regional Policy, Polish Medical Research Agency. 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Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. 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