- Transmission of information or data, when it is essential for an amount of energy to reach the receiver to restore the transmitted information;\n - Transmission of electric energy in the form of electromagnetic field, when the energy transfer efficiency is essential, the power being used to energize the receiving equipment.\n \nThe second form of energy transfer is the subject of this book.",isbn:"978-953-51-2468-9",printIsbn:"978-953-51-2467-2",pdfIsbn:"978-953-51-6659-7",doi:"10.5772/61488",price:119,priceEur:129,priceUsd:155,slug:"wireless-power-transfer-fundamentals-and-technologies",numberOfPages:140,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"2a20c1dde39792560dab996742f0e73c",bookSignature:"Eugen Coca",publishedDate:"June 29th 2016",coverURL:"https://cdn.intechopen.com/books/images_new/5187.jpg",numberOfDownloads:19567,numberOfWosCitations:24,numberOfCrossrefCitations:21,numberOfCrossrefCitationsByBook:3,numberOfDimensionsCitations:36,numberOfDimensionsCitationsByBook:4,hasAltmetrics:1,numberOfTotalCitations:81,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"October 12th 2015",dateEndSecondStepPublish:"November 2nd 2015",dateEndThirdStepPublish:"February 6th 2016",dateEndFourthStepPublish:"May 6th 2016",dateEndFifthStepPublish:"June 5th 2016",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,7",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"5766",title:"Dr.",name:"Eugen",middleName:null,surname:"Coca",slug:"eugen-coca",fullName:"Eugen Coca",profilePictureURL:"https://mts.intechopen.com/storage/users/5766/images/1434_n.jpg",biography:"Eugen Coca is currently Associate Professor and Director of the Computers, Electronics and Automation Department at the Stefan cel Mare University of Suceava, Romania. He is also the Technical Manager and Scientific Coordinator of the Electromagnetic Compatibility Laboratory—EMCLab.ro, from the same university, and also Executive Editor of Advances in Electrical and Computer Engineering journal. His current research interests are in the areas of electromagnetic compatibility, design, testing, and compliance of domestic and automotive products with emissions and immunity standards, wired and wireless communications, wireless sensor networks and general microcontroller systems and their applications. He authored or co-authored three books or book chapters, and more than 50 papers in international journals or conferences. He has also been involved as project manager or researcher in more than 40 research projects, public or privately funded. He received his BSEE and the PhD in Electronics Engineering from the Gheorghe Asachi Technical University of Iasi, Romania, in 1994 and 2001, respectively. Dr. Coca teaches Electromagnetic Compatibility, Wireless Sensor Network, Mobile and Satellite Communications, Digital and Analog Communication Systems, and Computer-Aided Design.",institutionString:null,position:"Associate Professor",outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"1",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"756",title:"Power Electronics",slug:"power-electronics"}],chapters:[{id:"50520",title:"Fundamentals of Inductively Coupled Wireless Power Transfer Systems",doi:"10.5772/63013",slug:"fundamentals-of-inductively-coupled-wireless-power-transfer-systems",totalDownloads:4629,totalCrossrefCites:4,totalDimensionsCites:8,hasAltmetrics:1,abstract:"The objective of this chapter is to study the fundamentals and operating principles of inductively coupled wireless power transfer (ICWPT) systems. This new technology can be used in various wireless power transfer applications with different specifications, necessities, and restrictions such as in electric vehicles and consumer electronics. A typical ICWPT system involves a loosely coupled magnetic coupling structure and power electronics circuitries as an integrated system. In this chapter, the emphasis is placed on the magnetic coupling structure, which is the most important part of the system. Although this technology has motivated considerable research and development in the past two decades, still there are several theoretical studies such as the level of the operating frequency, operating at high secondary circuit quality factor, coupling efficiency, etc., that need further investigation to fully develop the governing mathematical relationships of this technology.",signatures:"Ali Abdolkhani",downloadPdfUrl:"/chapter/pdf-download/50520",previewPdfUrl:"/chapter/pdf-preview/50520",authors:[{id:"179618",title:"Dr.",name:"Ali",surname:"Abdolkhani",slug:"ali-abdolkhani",fullName:"Ali Abdolkhani"}],corrections:null},{id:"51032",title:"Analysis of Wireless Power System Efficiency in Dependency on Configuration of Resonant Tank",doi:"10.5772/62998",slug:"analysis-of-wireless-power-system-efficiency-in-dependency-on-configuration-of-resonant-tank",totalDownloads:2032,totalCrossrefCites:2,totalDimensionsCites:2,hasAltmetrics:0,abstract:"This chapter compares various compensation methods for resonant coupling of the wireless energy transfer system. A proposed analysis is particularly relevant to any application where contactless battery charging is used. Main parameters that are investigated include efficiency and electrical variables (current and voltage) of the circuit. In order to analyze the most suitable solution of coupling compensation, the relevant equations are graphically interpreted for each discussed circuit topology. Finally, this chapter provides the recommendations how to design the wireless power-transfer system with the highest possible efficiency for the given system parameters (switching frequency and transmitting distance).",signatures:"Michal Frivaldsky, Pavol Spanik, Peter Drgona, Viliam Jaros and\nMarek Piri",downloadPdfUrl:"/chapter/pdf-download/51032",previewPdfUrl:"/chapter/pdf-preview/51032",authors:[{id:"180825",title:"Dr.",name:"Michal",surname:"Frivaldsky",slug:"michal-frivaldsky",fullName:"Michal Frivaldsky"},{id:"185361",title:"Prof.",name:"Pavol",surname:"Spanik",slug:"pavol-spanik",fullName:"Pavol Spanik"},{id:"185362",title:"Dr.",name:"Peter",surname:"Drgona",slug:"peter-drgona",fullName:"Peter Drgona"},{id:"185363",title:"MSc.",name:"Marek",surname:"Piri",slug:"marek-piri",fullName:"Marek Piri"},{id:"185364",title:"MSc.",name:"Viliam",surname:"Jaros",slug:"viliam-jaros",fullName:"Viliam Jaros"}],corrections:null},{id:"51254",title:"Wireless Power Transfer by Using Magnetically Coupled Resonators",doi:"10.5772/64031",slug:"wireless-power-transfer-by-using-magnetically-coupled-resonators",totalDownloads:5015,totalCrossrefCites:4,totalDimensionsCites:6,hasAltmetrics:1,abstract:"In this chapter, a wireless power transmission system based on magnetic resonance coupling circuit was carried out. Mathematical expressions of optimal coupling coefficients were examined with the coupling model. Equivalent circuit parameters were calculated with Maxwell 3D software, and then, the equivalent circuit was solved using MATLAB technical computing software. The transfer efficiency of the system was derived using the electrical parameters of the equivalent circuit. System efficiency was analyzed depending on the different air gap values for various characteristic impedances using PSIM circuit simulation software. Since magnetic resonance coupling involves creating a resonance and transferring the power without the radiation of electromagnetic waves, resonance frequency is a key parameter in system design. The aim of this research was to define the efficiency according to variations of coefficients in wireless power transfer (WPT) system. In order to do that, the calculation procedure of mutual inductance between two self-resonators is performed by Maxwell software. Equivalent circuit is solved in circuit simulator PSIM platform. The calculations show that using the parameters that are obtained by magnetic analysis can be used for the equivalent circuit which has the capability to provide the efficiency using electrical quantities. The chapter discusses the application of this approach to a coil excited by a sinusoidal voltage source and a receiver coil, which receives energy voltage and current. Both could be obtained to calculate the instantaneous power and efficiency. To do so, the waveforms for voltage and current were obtained and computed with the PSIM circuit simulator. As the air gap between the coils increased, the coupling between the coils was weakened. The impedance of the circuit varied as the air gap changed, affecting the power transfer efficiency. In order to determine the differences between the software programs, efficiency values were calculated using three kinds of software. And it is concluded that equivalent circuit analysis by means of numerical computing is proper to obtain the voltage and current waveforms. Correspondingly, transmission efficiency can be calculated using the electrical relations.",signatures:"Ali Agcal, Selin Ozcira and Nur Bekiroglu",downloadPdfUrl:"/chapter/pdf-download/51254",previewPdfUrl:"/chapter/pdf-preview/51254",authors:[{id:"19888",title:"Dr.",name:"Nur",surname:"Bekiroglu",slug:"nur-bekiroglu",fullName:"Nur Bekiroglu"},{id:"179716",title:"Dr.",name:"Selin",surname:"Ozcira",slug:"selin-ozcira",fullName:"Selin Ozcira"},{id:"186130",title:"Dr.",name:"Ali",surname:"Agcal",slug:"ali-agcal",fullName:"Ali Agcal"}],corrections:null},{id:"50788",title:"Innovative Wireless Power Receiver for Inductive Coupling and Magnetic Resonance Applications",doi:"10.5772/63341",slug:"innovative-wireless-power-receiver-for-inductive-coupling-and-magnetic-resonance-applications",totalDownloads:2568,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"This chapter presents a wireless power receiver for inductive coupling and magnetic resonance applications. The active rectifier with shared delay-locked loop (DLL) is proposed to achieve the high efficiency for different operation frequencies. In the DC–DC converter, the phase-locked loop is adopted for the constant switching frequency in the process, voltage, and temperature variation to solve the efficiency reduction problem, which results in the heat problem. An automatic mode switching between pulse width modulation and pulse frequency modulation is also adopted for the high efficiency over the wide output power. This chip is implemented using 0.18 μm BCD technology with an active area of 5.0 mm × 3.5 mm. The maximum efficiency of the active rectifier is 92%, and the maximum efficiency of the DC–DC converter is 92% when the load current is 700 mA.",signatures:"Young-Jun Park, Hongjin Kim, Hyung-Gu Park and Kang-Yoon Lee",downloadPdfUrl:"/chapter/pdf-download/50788",previewPdfUrl:"/chapter/pdf-preview/50788",authors:[{id:"180098",title:"Prof.",name:"Kang-Yoon",surname:"Lee",slug:"kang-yoon-lee",fullName:"Kang-Yoon Lee"},{id:"185231",title:"Mr.",name:"Young-Jun",surname:"Park",slug:"young-jun-park",fullName:"Young-Jun Park"},{id:"185232",title:"Dr.",name:"Hyung-Gu",surname:"Park",slug:"hyung-gu-park",fullName:"Hyung-Gu Park"}],corrections:null},{id:"50455",title:"Microwave Power Transmission Based on Retro-reflective Beamforming",doi:"10.5772/62855",slug:"microwave-power-transmission-based-on-retro-reflective-beamforming",totalDownloads:2281,totalCrossrefCites:3,totalDimensionsCites:7,hasAltmetrics:0,abstract:"Microwave power transmission has the potential to supply wireless power to portable/mobile electronic devices over long distances (on the order of meters or even kilometers) efficiently. Nevertheless, several technical challenges remain to be resolved in order to accomplish practical microwave power transmission systems, including (i) minimizing power loss due to microwave propagation, (ii) preventing humans and other electrical systems from exposure to excessive microwave radiation, and (iii) reconfiguring wireless power transmission in reaction to environmental changes (such as physical movements of portable devices) in real time. In this chapter, a microwave power transmission scheme based on retro-reflective beamforming is proposed to address the above challenges. In the retro-reflective beamforming, wireless power transmission is guided by pilot signals. To be specific, one or more than one mobile device(s) broadcast pilot signals to their surroundings, and based on analyzing the pilot signals, a wireless power transmitter delivers focused power beam(s) onto the mobile device(s). Preliminary numerical and experimental results are presented to demonstrate the feasibility of the proposed retro-reflective beamforming scheme.",signatures:"Xin Wang and Mingyu Lu",downloadPdfUrl:"/chapter/pdf-download/50455",previewPdfUrl:"/chapter/pdf-preview/50455",authors:[{id:"179390",title:"Prof.",name:"Xin",surname:"Wang",slug:"xin-wang",fullName:"Xin Wang"},{id:"183027",title:"Dr.",name:"Mingyu",surname:"Lu",slug:"mingyu-lu",fullName:"Mingyu Lu"}],corrections:null},{id:"51247",title:"A Review of Dynamic Wireless Power Transfer for In‐Motion Electric Vehicles",doi:"10.5772/64331",slug:"a-review-of-dynamic-wireless-power-transfer-for-in-motion-electric-vehicles",totalDownloads:3042,totalCrossrefCites:7,totalDimensionsCites:12,hasAltmetrics:0,abstract:"Dynamic wireless power transfer system (DWPT) in urban area ensures an uninterrupted power supply for electric vehicles (EVs), extending or even providing an infinite driving range with significantly reduced battery capacity. The underground power supply network also saves more space and hence is important in urban areas. It must be noted that the railways have become an indispensable form of public transportation to reduce pollution and traffic congestion. In recent years, there has been a consistent increase in the number of high‐speed railways in major cities of China, thereby improving accessibility. Wireless power transfer for train is safer and more robust when compared with conductive power transfer through pantograph mounted on the trains. Direct contact is subject to wear and tear; in particular, the average speed of modern trains has been increasing. When the pressure of pantograph is not sufficient, arcs, variations of the current, and even interruption in power supply may occur. This chapter provides a review of the latest research and development of dynamic wireless power transfer for urban EV and electric train (ET). The following key technology issues have been discussed: (1) power rails and pickups, (2) segmentations and power supply schemes, (3) circuit topologies and dynamic impedance matching, (4) control strategies, and (5) electromagnetic interference.",signatures:"Kai Song, Kim Ean Koh, Chunbo Zhu, Jinhai Jiang, Chao Wang and\nXiaoliang Huang",downloadPdfUrl:"/chapter/pdf-download/51247",previewPdfUrl:"/chapter/pdf-preview/51247",authors:[{id:"179138",title:"Prof.",name:"Kai",surname:"Song",slug:"kai-song",fullName:"Kai Song"},{id:"179160",title:"Dr.",name:"Jinhai",surname:"Jiang",slug:"jinhai-jiang",fullName:"Jinhai Jiang"},{id:"179161",title:"Prof.",name:"Chunbo",surname:"Zhu",slug:"chunbo-zhu",fullName:"Chunbo Zhu"},{id:"180988",title:"Dr.",name:"Xiaoliang",surname:"Huang",slug:"xiaoliang-huang",fullName:"Xiaoliang Huang"},{id:"180989",title:"Dr.",name:"Kim Ean",surname:"Koh",slug:"kim-ean-koh",fullName:"Kim Ean 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\r\n\tIn the last two decades, an impeccable advancement in nanotechnology encouraged global scientific intellect for constant contemplation of its ramifications in biomedical applications. Nanomedicine, a medical specialty that uses the advances in nanotechnology, is mostly explored to prevent, detect and treat many diseases, cancer is the most pernicious among them. A wide range of engineered nanomaterials is used for a wide variety of biomedical applications, especially disease diagnostic, drug delivery, physiological state sensing or alteration of actuation functions in a living body, etc. Organic and inorganic nanomaterials are emerging as promising cancer therapeutic and diagnostic techniques. To target specific tumor tissues, polymeric micelles, liposomes, dendrimers, and other nanoparticles have been explored for their potential to assemble in leaky tumor circulatory networks. Further, targeting cancer at the cellular and molecular level has also been achieved by various surface-modified nanomaterials carrying specific cargo. Moreover, image and diagnostic-based nanometric multimodal therapeutic modalities will be explored as flexible theranostics having a dual potential to treat and diagnose cancer. Biogenic nanomaterials for cancer therapy and imaging will also be explored in this book. This book will concentrate on the use of nanotechnology in biomedical diagnostics, treatments, drug delivery systems, and other possible clinical applications.
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Paul, Dr. Jyotirmoi Aich, Prof. Soumya Basu and Dr. Anubhab Mukherjee",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11984.jpg",keywords:"Polymeric Nanoparticles, Lipoidal Nanoparticles, Therapy, Carbon Nanotube, Bioavailability, Theranostics, Nanobiotechnology, Nanoelectronics, Tumour Imaging, Novel Biomaterials, Regenerative Medicine, Stem Cell Therapy",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"June 8th 2022",dateEndSecondStepPublish:"July 6th 2022",dateEndThirdStepPublish:"September 4th 2022",dateEndFourthStepPublish:"November 23rd 2022",dateEndFifthStepPublish:"January 22nd 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"11 hours",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Dr. Paul is the recipient of many awards, including the prestigious UCLA Vice Chancellor’s Award, and was nominated for Paul Boyer’s award. He is a member of multiple editorial boards and has one registered patent. Dr. Paul is a senior member of the Institute of Electrical and Electronics Engineers (IEEE) and also a member of many esteemed societies, including the Royal Society of Biology (MRCB), the American Association for Cancer Research (AACR), and the International Society of Biotechnology (ISBT).",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul",profilePictureURL:"https://mts.intechopen.com/storage/users/319365/images/system/319365.png",biography:"Manash K. Paul is a Principal Investigator and Scientist at the University of California Los Angeles. He has contributed significantly to the fields of stem cell biology, regenerative medicine, and lung cancer. 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\n
1. Introduction
\n
Over the last two decades, since the Rio de Janeiro’s UN Conference on Environment and Development (UNCED) in 1992, a growing demand for policy making in the forest sector has emerged at the global level in connection to the challenge of climate change.
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The UN-declared 2011 “International Year of Forests” ended with some important steps forward achieved at the Durban’s 17th Conference of the Parties of the United Nations Framework Convention on Climate Change [Perugini et al., 2012].
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Meanwhile, the evolution of this process has progressively resulted in an articulated international regulatory framework based on a plurality of agreements and policy initiatives coping with the complex issue of protecting the forest ecosystems and managing them in accordance to the principles of sustainability.
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Historically, among the landmark steps in the development of regulatory principles and schemes addressing the forest sector and recognizing the inner multi-functionality of forest ecosystems in the international environmental law, it is worth mentioning, for instance, the Convention on Biological Diversity (CBD), that dedicates a detailed work programme to protect the biodiversity stored in forests, and the United Nations Convention to Combat Desertification (UNCCD), that recognizes the relevance of the role of forests in fighting the process of desertification connected with global warming [EUROPEAN COMMISSION, 2010].
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In any case, as far as international schemes are concerned, and given the intrinsic trans-boundary dimension of the multiple, interconnected ecological, economic and social functions performed by forests as well as of the potential effects of climate change dynamics on them, the implementation of rational policy making in the sector requires forms of supranational endorsement flexible enough to facilitate sustainable forest management decisions that can be suitable to the different characteristics and conditions of the various forest sites existing on the Earth.
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At the European level, Sustainable Forest Management (SFM) was adopted by the EU and its Member States as the central approach to forestry since 1993, with the adoption of Helsinki Resolution 1 the Ministerial Conference on the Protection of Forests in Europe.
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Since then, European institutions refer to SFM as “the stewardship and use of forest lands in a way, and at a rate, that maintains their biodiversity, productivity, regeneration capacity, vitality and their potential to fulfill, now and in the future, relevant ecological, economic and social functions, at local, national and global levels, and that does not cause damage to other ecosystems” [MCPFE, 1993].
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As the policy principles are defined, when aiming at implementing evidence-based sustainable forest management, taking account of the potential trade-offs and mutual benefits among the functions of mitigation and adaptation to climate change, as well as between the many other forest functions, becomes a crucial task to be undertaken [Spittlehouse and Stewart, 2003, FOREST EUROPE 2011].
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Though, since the UNFCCC recognized the role of forests in the balance of global greenhouse gas emissions, a broader emphasis was traditionally put on their potential for climate change mitigation, either by reducing emission as a source for potentially wood-based renewable energy and as a sink for carbon sequestration [Guariguata et al., 2008, Campbell et al., 2009, FOREST EUROPE 2011].
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It is nevertheless since 1990s that evidence for Europe continues to show that, according to current climate scenarios, forest ecosystems in this part of the world are expected to be particularly vulnerable to varying climate conditions.
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In this context, the adaptation of the European forest sector to climate change represents a priority for ensuring that the provision of goods and services from forests can be maintained [Lindner, M. Kolström 2008, FAO 2011].
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However, the development of adaptation measures is bound to a number of challenges to be dealt with in a context of scientific uncertainty. On the one hand, there is yet limited knowledge about the vulnerability of ecosystems and species as well as climate change impacts on the functional characteristics of forests in different bio-climatic zones (inherent adaptive capacity). On the other, adaptation measures also depends on a range of socio-economic conditions, whose future adjustments are uncertain [Burton et al., 2002, Spittlehouse and Stewart, 2003, Lindner, Kolström, 2008].
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\n
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2. EU and Alpine legal framework for mitigation and adaptation in the forest sector
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At the EU level, work is in progress and actions have been proposed to support and enhance sustainable forest management and the role of forest multi-functionality in the contribution to the Lisbon EU 2020 Strategy and the Gothenburg Agenda on sustainable development.
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Remarkably forerunning to the processes at stake, the EU Forest Action Plan [European Commission, 2006], building on the Council Resolution of 15 December 1998 on a forestry strategy for the European Union, have identified four main guiding objectives commonly on which to ground the implementation of a coordinated forest policy by the EU and Member States that need to be address the concepts of multi-functionality and sustainable forest management:
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improving long-term competitiveness;
improving and protecting environment;
contributing to quality of life;
fostering communication and coordination
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More specifically, in order to implement these objectives, the Action Plan outlines eighteen Key Actions.
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All these actions, in view of their intrinsic interrelation, have a relevance to be taken into account when devising adaptation strategies in the forest sector. Some of them, however, together with the measures outlined for their practical implementation, can be intrinsically seen as directly referable to policy-building for adaptation to climate change:
\n
the support of research and studies on climate change impacts and adaptation measures (Key Action 6);
the enhancement of EU forests protection from biotic and abiotic hazards also by encouraging cooperation between Member States to study particular regional problems with the condition of forests (Key Action 9);
maintain and enhance the protective functions of forests against the increasing threats of natural disasters and extreme events also through coordinated monitoring and planning, awareness raising and knowledge transfer on natural hazard and risk management, with a focus on mountain areas (Key Action 11)
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A report on the state of the art of its implementation of the EU Forest Action Plan 2007 – 2011 will be presented to the Council and the European Parliament during 2012, in order to evaluate potential further developments.
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Relevant to the analytic scope of the present paper, the EU Forest Action Plan has aimed at mainstreaming adaptation of European forests to climate change as a clear policy objective in a context where, in compliance with the subsidiarity principle, competence in forest policy lies primarily with the Member States. The role of the EU in forest policy, in fact, technically applies according to the principle of vertical subsidiarity (art. 5 of the EU Treaty), consequently meaning that the EU competencies are expected to simply perform in those cases where action by Member States is not sufficient and can be better achieved at the Union level.
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With regard to forest policies, in particular, the EU role was historically limited to monitor and report on the state of EU forests; anticipating and stimulating attention of Member States on emerging global challenges and trends; proposing and coordinating or supporting early action at the EU level.
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Moving in this complex, multi-dimensional institutional framework, innovative policy approaches have to be conceived to address the challenges posed by the need to ensure sustainability and adaptation of those forest resources that, due to their peculiar vulnerability and trans-boundary relevance, require apt regional policy-making strategies.
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Not for a case, it has been recently affirmed by the FAO [2011] that there is a need for measures to protect mountain forests to be based on enhanced coordination at international and national levels, in consideration of local specificities and by integrating forest issues into broader policies and programmes.
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Here, we focus on the Alpine forests and their specific functions, with the aim of analyzing a potential action framework for an effective and evidence-based policy building that can devise adaptive forest management strategies suitable to the peculiar adaptation needs of the area, representing at the same time an integrated element of the guiding measures and principles set out at the multiple level of decision making (EU, Alpine, national, local) co-existing in a multinational model of governance and cooperation.
\n
Alpine forests retain the characteristics to represent an important pilot area for implementing adaptive strategies under consideration here, for a range of institutional, ecological and socio-economic reasons.
\n
Under an institutional perspective, the Alpine Convention, quite peculiarly in international environmental law with regard to this sector, provides a regulatory framework for implementation of transboundary cooperation in sustainable forest management: the Alpine Convention was in fact the first framework agreement at the level of international law on the protection and sustainable development of a transboundary mountain region.
\n
More precisely, the Alpine Convention is an international treaty between the Alpine countries (Austria, France, Germany, Italy, Liechtenstein, Monaco, Slovenia and Switzerland) as well as the EU open to signature in Salzburg (Austria) on 7 November 1991, aimed at promoting sustainable development in the Alpine area and at protecting the interests of the people living within it, embracing the environmental, social, economic and cultural dimensions.
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In any case, as commonly designed within the international environmental law due to the technical and scientific complexity of the provisions’ contents, the implementation of the general principles of the framework agreement is to be further delegated to the Protocols [Munari, 2006].
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For implementing the Alpine Convention’s goals for the forest sector, since 1996, the “Mountain Forests” Protocol - done at Brdo (Slovenia) on 27th February of that year - identifies a set of specific functions of Alpine mountain forests whose conservation and enhancement is to be considered as a priority in the overall regional sustainable development policy.
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By the attribution of a legal status to these functions, the Contracting Parties have therefore designed a platform for international cooperation (art. 4) at multiple levels of decision-making (art. 3) to pursue the preservation and improvement of forest assets even in a cross-sectoral perspective with other policy fields, also by means of cooperation in research, education and information (Chapter III).
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Particularly relevant in a perspective of climate change adaptation, the “Mountain Forest” Protocol highlights the relevance of the protective function (art. 6), the economic function (art. 7), and of the functions of social and ecological character such as, among the others, water resources, clean air, biodiversity and recreation (art. 9).
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3. Major impacts of climate change on Alpine forests and their functions
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Climate change is expected to determine major ecological, social and economic effects on Alpine forests: as a result of the combined effects of land abandonment and decrease of limiting tree growth factors at higher altitudes because of higher temperatures, the process of forest cover expansion in the Alps - currently around 7.5 million ha, the 43% of the total Alpine land surface [EEA, 2009] - which is ongoing in the last decades is expected to continue, probably at higher rates.
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Climate change may also affect tree growth patterns and species distribution, as well as increase the spread and intensity of, respectively, abiotic (fires, storms, drought, precipitations, atmospheric pollution) and biotic (pests and diseases) disturbances. These climate change impacts may therefore trigger plural interdependent effects that could alter a range of socially and economically critical Alpine-specific forest functions.
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Nevertheless, knowledge still lacks on the magnitude and trends of these impacts and on how they may affect, positively or negatively, the livelihood of highland and lowland communities in a socio-economic perspective [IPCC, 2007, Lindner, Kolström et al. 2008, FAO, 2011].
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In this line, the mentioned research outcomes, policy making guidelines and experience in Alpine forest adaptive management have suggested to place a particular focus on:
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the protective function for human infrastructures from natural hazards like flooding, debris flows, landslides, avalanches and rockfalls, is one of the most important function played by mountain forests: for instance, 20% of Austria’s forests is considered as having a protective role, meanwhile 63% of Bavarian forests are declared as having a protective function against soil erosion and 43% against avalanches, in Germany. Concerning the economic and social value related to mountain forests’ protective function in Alpine territories, a telling example comes from the Swiss Alps where it has been estimated that, in their absence, the cost of ensuring protection against avalanches using permanent ad hoc defense structures would be around some 89 billion Euros, 5-20 times more than that of maintaining healthy protection forests [FAO, 2011]. However, protection forests are sensitive to varying climate dynamic, even though it is difficult to assess the complexity of interaction, as it depends on many structural and compositional properties. In theory, diverse species composition, sufficient natural regeneration and an optimal structure favour the forests´ protective function. As climate change could significantly alter the plant´s phenology, physiology and distribution, strategies have to be implemented in the Alps to deal with the potentially increased silvicultural challenges already at play - poor regeneration, low proportion of medium-aged trees, exposure to intensified natural disturbances [Lindner, Kolström et al., 2008, FAO, 2011]. In this regard, some significant actions have already been undertaken at the pan-alpine level. In particular, the MANFRED Project “Management Strategies to adapt Alpine Space forests to climate change risks”, launched in the context of the European Territorial Cooperation Alpine Space Programme 2007 - 2013 has developed a framework to undertake cooperative action in research and policy-making with regard to assessing the impacts of climate change on forests all over the Alpine arc, with a special focus on the interrelation among climate change scenarios and biotic and abiotic hazard factors dynamics. The expected results goes precisely in the direction of improving knowledge-based transnational cooperation and experience sharing in forest adaptive management at the Alpine level in order to address, among the others, the capacity of forests in the Alps of enduring their protective function also in a context of varied climatic conditions.
The productive function of wood and non-wood forest goods and services may be consistently altered by climate change with both a) potential pros and cons as well as with b) trade-offs between the different potential economic uses of the same forest parcel. In the first case, for instance, wood productivity is expected to increase at higher elevations as a consequence of climatic changes as far as the water supply is sufficient, meanwhile at lower elevations changes species competition and adaptive capacity to natural disturbances may lead to decreasing productivity, also affecting the economic profitability patterns and their differences existing between highland and lowland forestry [Lindner, Kolström et al., 2008, FAO, 2011]. Instead, referring to different potential forested land uses, by the way of example, trade-offs exist between use of forest as carbon sinks or for biomass production, which are determined by both socio-economic conditions such as market prices and demand for biomass energy from forests as well as climate change-related effects [Lindner, Kolström et al., 2008]. In fact, studies suggest that the Alps are expected to maintain their carbon sink capacity at least for the first half of the 21st century, while increasing respiration rates and natural disturbances at low elevation sites may decrease thus making Alpine forests a carbon source [Karjalainen et al., 2002, Thürig et al., 2005, Zierl and Bugmann, 2007].
The social and economic functions of forests include other forest services such as biodiversity, fresh and clean air water supply, or landscape that are finally relevant for the provision of other cultural and tourist-related economic ecosystem services potentially bearing site-specific positive externalities. The value of these positive externalities is often not disclosed on markets as they are generally public goods, but their importance is crucial for the livelihood of communities inside and outside the mountain regions [TEEB, 2010; FAO, 2011]. Hence, their assessment is fundamental for the implementation of rational public choices in forest management adaptation planning.
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4. Adaptation strategies for the Alpine forest sector
\n
The Alpine region as a whole can be considered as a particularly vulnerable area to the impacts of climate change, both physically and socially, with a clear need to build resilience through improved adaptation capacity. A strong need for adaptation has emerged from several scientific and policy-oriented sources (including the Climate Action Plan adopted by the Alpine Convention in Evian, 2009), experiences conducted in the Alpine countries and in other literature (EEA 2009, OECD 2007). In particular the necessity to focus and undertake cooperative research on the adaptation side of mountain forests in the Alps has been increasingly recognized as a central strategic topic in the framework of the Territorial Cooperation goals of the “Alpine Space Programme”. As recalled above, the MANFRED Project, for example, directly addresses the topic of adaptation in Alpine forests to the impacts of climate change. In short, the project was focused on the assessment of potential future climate and land use dynamics´ patterns, on the related impacts of them on abiotic and biotic hazard factors, on the historical frequency of and statistics on extreme events and related management practices in the Alpine forests, and on the sharing of knowledge about protection forests engineering in the Alps. All these fields of activity are expected to contribute to the definition of shared guidelines for sustainable forest adaptive management at the Alpine level, also based on the direct involvement of relevant stakeholders and the sound consideration of their preferences during the multiple stages of the project implementation.
\n
Some forest-based adaptation activities have been recently identified as including monitoring and maintaining forest health, vitality and diversity; implementing integrated forest fire management; enhancing landscape connectivity and reducing forest fragmentation; monitoring and removing invasive species and addressing pest and disease threats; implementing reduced-impact logging; selecting appropriate species for use in planted forests; undertaking forest restoration and rehabilitation, particularly on slopes, through specific measures and tools that can facilitate the adaptation process [Ciccarese et al. 2012].
\n
However, the concrete design and implementation of climate change adaptive strategies as part of sustainable forest management requires making policy choices between sets of different adaptation options often implying potential co-benefits and trade-offs between environmental, social and economic functions [Spittlehouse and Stewart, 2003, FOREST EUROPE 2011].
\n
Moreover, choices between adaptation measures have to be taken in a long-term perspective - as the long life-span and growing conditions of trees does not allow for rapid adaptation to environmental change in a context of temperature increase in the Alps over the last century that is already twice the global average (about 1.5°C), with a slightly growing tendency at higher altitudes [Houghton et al., 2001, Casty et al., 2005, IPCC, 2007]
\n
Nevertheless, there is still a high degree of scientific uncertainty about regional future climate conditions and how they will impact on forests health and growing patterns [Roetzer, 2005; IPCC, 2007, Lindner, Kolström 2008]. For forest sector policy-making to be effective, reliable information has to be available: collaborative, interdisciplinary research has to be further developed in order to provide policy-makers and relevant stakeholders inside and outside the forest sector with the necessary evidence-based tool for rational decision-making [FOREST EUROPE 2011, FAO 2011]. Furthermore, research demonstrated the ability to develop sensible decision support systems for different sectors, that can be applied in different regions (some examples for the Alps: Climalptour, SHARE, etc.).
\n
\n
\n
5. Policy framework and perspectives for policy building
\n
The actual use of forests can be socially and historically rooted in each considered area [Agnoletti and Anderson a) and b), 2000, Williams, 2006]. Different forest uses and policies can bring different contributions to regional economic development trends, by producing variable degrees of income and wealth from forest marketed and non-marketed services [FOREST EUROPE 2011].
\n
The historical persistence of some forest uses observed locally and the priorities set by policy makers at different levels (e.g. increasing wood supply and mobilization are common to several European, Alpine and non-Alpine regions’ forest policy) suggest to assign different relative weights to the contribution that each forest function supplies to the economy and society in different countries and sub-regions.
\n
In turn, this discretionary and site-specific weighting is likely to impact on the actual mix of adaptation measures that regional governments will support, incentivize and implement.
\n
Thus, when selecting sector-specific adaptation measures, decision makers are called to inspect:
\n
the physical and ecological features of the region that participate in determining its inherent adaptive capacity [Lindner and Kolström 2008, EEA 2009],
the composition and historical roots of the regional economy – where some economic indicators for the profitability of forestry have been calculated for EU forests [Kovalcik 2011],
the priorities set (or to be set) at different political levels in the region under inquiry [Lindner and Kolström 2008].
\n
From this situation, a few guiding principles for the definition of suitable adaptation policies can be extracted:
\n
climate change impacts on the forest functions can assume a variable social and economic weight, on the basis of some situational variables, which may include the structure of the economy, the forest sector contribution to regional GDP, the regional labor market structure, the social consequences of policies and trends observed in the forest sector, the functions and services provided by forest ecosystems, and their formal understanding from the scientific community;
public awareness existing on climate change impacts at the local level is a key factor to be taken into account when defining adaptation policies. In particular the perceptions of policy makers, of the scientific community, of qualified stakeholders and of the general public on the relative weights and role of the climate change-affected forest functions at the regional level should be attributed a specific policy focus. Namely, particularly relevant is the dissemination of the available information to user groups and forest owners [Lindner and Kolström 2008, FAO 2011];
considerations on, and choices about trade-offs and co-benefits eventually deriving from adaptation measures in the forest sector are likely to be context-specific, i.e. dependent on the framework conditions observed in the region at the economic, social, ecological and policy-level.
\n
Current figures reveal that in Europe the average share of forestry in the GDP is modest and corresponds on average to 0,31%, with slightly higher values in Austria and Slovenia. [FOREST EUROPE 2011]. At the same time, entrepreneurial income per hectare shows very variable values across EU [Kovalcik, 2011].
\n
In such a context, the regions where forestry and forest policies have only marginally developed, as it is the case also with some Alpine countries, phenomena of policy change and “paradigm shift” towards a comprehensive adaptation strategy to climate change and a concomitant sustainable forest management may be triggered only by a composite set of factors.
\n
Among them, the following can be recalled: the results of scientific research, the increased understanding of the physical mechanisms behind forest functions, the novel knowledge available on the possible ecological, economic and social impacts of climate change, and the growth opportunities for the forest sector which have been identified at the economic and policy-analysis level, also in the framework of the 2012 United Nations Conference on Sustainable Development (UNCSD) in Rio de Janeiro, that explicitly addressed the theme of “Green economy in the context of sustainable development and poverty eradication [OECD 2011, UNEP 2011, UNECE 2012]. Conversely, the process of change in Alpine forest management may be hindered by the persistence of a high degree of regional vulnerability.
\n
\n
\n
6. Conclusions
\n
Building resilience to climate change in the Alpine forest sector by implementing suitable adaptation policies can therefore facilitate the sector’s innovation and change. The process of policy change in addressing the challenges of the forest sector can be read as the consequence of an iterative feedback impacting on the framework conditions of the sector and the regional economy at large. This may stimulate a learning process consisting in information feedbacks being able to revise the behavioral model of decision making [Sterman, 1994], and potentially inducing increasing modifications in forest management.
\n
In conclusion, such a feedback effect can be supported by several factors and conditions, that participate in determining the intensity and potential for change of the forest policies, including:
\n
the presence (or absence) of already openly defined policy goals (policy stability of the forest sector);
the existing stakeholders’ claims and expectations;
the expected impacts of climate change on the regional economy and society, and their relative weights;
the resilience of Alpine forests to climate change and their actual and potential contribution to societal adaptation [Innes et al., 2009];
the possible social and economic benefits that can derive from a more efficient forest management and target-oriented expenditure (e.g. reflecting in higher entrepreneurial revenues and employment levels, differently from the present situation) [FOREST EUROPE, 2011];
the resulting attractiveness (in terms of expected economic, ecological and societal benefits) of the “paradigm shift” itself for key regional stakeholders and policy makers.
\n
\n \n',keywords:null,chapterPDFUrl:"https://cdn.intechopen.com/pdfs/44073.pdf",chapterXML:"https://mts.intechopen.com/source/xml/44073.xml",downloadPdfUrl:"/chapter/pdf-download/44073",previewPdfUrl:"/chapter/pdf-preview/44073",totalDownloads:1810,totalViews:158,totalCrossrefCites:0,totalDimensionsCites:1,totalAltmetricsMentions:0,impactScore:0,impactScorePercentile:16,impactScoreQuartile:1,hasAltmetrics:0,dateSubmitted:"May 15th 2012",dateReviewed:"March 1st 2013",datePrePublished:null,datePublished:"August 28th 2013",dateFinished:"April 4th 2013",readingETA:"0",abstract:null,reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/44073",risUrl:"/chapter/ris/44073",book:{id:"3403",slug:"management-strategies-to-adapt-alpine-space-forests-to-climate-change-risks"},signatures:"Luca Cetara and Federico Mannoni",authors:[{id:"159989",title:"Dr.",name:"Luca",middleName:null,surname:"Cetara",fullName:"Luca Cetara",slug:"luca-cetara",email:"luca.cetara@eurac.edu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/159989/images/4819_n.jpg",institution:null},{id:"165433",title:"MSc.",name:"Federico",middleName:null,surname:"Mannoni",fullName:"Federico Mannoni",slug:"federico-mannoni",email:"mannoni.minambientest@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction ",level:"1"},{id:"sec_2",title:"2. EU and Alpine legal framework for mitigation and adaptation in the forest sector",level:"1"},{id:"sec_3",title:"3. Major impacts of climate change on Alpine forests and their functions ",level:"1"},{id:"sec_4",title:"4. Adaptation strategies for the Alpine forest sector ",level:"1"},{id:"sec_5",title:"5. Policy framework and perspectives for policy building ",level:"1"},{id:"sec_6",title:"6. Conclusions ",level:"1"}],chapterReferences:[{id:"B1",body:'\n \n \n \n Agnoletti\n M\n \n \n Anderson\n S\n \n eds.). Forest History: International Studies on Socioeconomic and Forest Ecosystem Change. In: IUFRO Research Series #2. New York, NY: CABI Publishing. 418\n 2000a\n \n '},{id:"B2",body:'\n \n \n \n Agnoletti\n M\n \n \n Anderson\n S\n \n eds.). Methods and Approaches in Forest History. In: IUFRO Research Series #3. New York, NY: CABI Publishing. 281\n 2000b\n \n '},{id:"B3",body:'\n \n Alpine ConventionProtocol on the Implementation of the Alpine Convention relating to Mountain Forests: “Mountain Forest” Protocol. 1996\n http://www.alpenkonvention.org/en/convention/protocols/Documents/protokoll_bergwaldGB.pdfaccessed 02 May 2012)\n '},{id:"B4",body:'\n \n Alpine ConventionAction Plan on Climate Change in the Alps: AC_X_B6_fr. ; 2009 http://www.alpconv.org/en/ClimatePortal/actionplan/Documents/AC_X_B6_en_new_fin.pdfaccessed 24 April 2012\n \n '},{id:"B5",body:'\n \n \n \n Brang\n P\n \n \n Schönenberg\n W\n \n \n Frehner\n M\n \n \n Schwitter\n R\n \n \n Thormann\n J\n \n \n Wasser\n B\n \n Management of protection forests in the European Alps: an overview. Forest, Snow and Landscape Research 2006\n \n '},{id:"B6",body:'\n \n \n \n Burton\n I\n \n \n Huq\n S\n \n \n Lim\n B\n \n \n Pilifosova\n O\n \n \n Schipper\n E. L\n \n From impacts assessment to adaptation priorities: the shaping of adaptation policy. Climate Policy 2002\n \n '},{id:"B7",body:'\n \n \n \n Campbell\n A\n \n \n Kapos\n V\n \n \n Scharlemann\n J. P. C\n \n et al\n Review of the literature on the links between biodiversity and climate change: impacts, adaptation and mitigation,. Secretariat of the Convention on Biological Diversity. Montreal: Technical Series n.124; 2009\n \n '},{id:"B8",body:'\n \n \n \n Casty\n C\n \n \n Wanner\n H\n \n \n Luterbacher\n J\n \n \n Esper\n J\n \n \n Böhm\n R\n \n Temperature and Precipitation Variability in the European Alps Since 1500. International Journal of Climatology 2005\n 1855\n 1880\n \n '},{id:"B9",body:'\n \n \n \n Ciccarese\n L\n \n \n Mattsson\n A\n \n \n Pettenella\n D\n \n\n Ecosystem services from forest restoration: thinking ahead. New Forests International Journal on the Biology, Biotechnology, and Management of Afforestation and Reforestation 2012. http://www.scribd.com/doc/54145282/European-Forestsaccessed 3 June 2012\n \n '},{id:"B10",body:'\n \n European CommissionGreen Paper on Forest Protection and Information in the EU: Preparing forests for climate change. COM (2010final.\n '},{id:"B11",body:'\n \n European CommissionCommunication from the Commission to the Council and the European Parliament on an EU Forest Action Plan. COM(2006\n \n '},{id:"B12",body:'\n \n European Environment AgencyRegional climate change and adaptation. The Alps facing the challenge of changing water resources. Copenhagen: EEA Report 8\n 2009\n 18\n 19and 51-53.\n '},{id:"B13",body:'\n \n FAOThe state of the world’s forests report, Rome: FAO; 2011\n \n '},{id:"B14",body:'\n \n FOREST EUROPEUNECE, FAO. State of Europe’s forests 2011status and trends in sustainable forest management in Europe: conference proceedings. 14.16 June. 2011, Oslo, Ministerial Conference on the Protection of Forests in Europe (FOREST EUROPE)\n '},{id:"B15",body:'\n \n \n \n Guariguata\n M. R\n \n \n Cornelius\n J. P\n \n \n Locatelli\n B\n \n \n Forner\n C\n \n \n Sanchez-azofeifa\n G\n \n Mitigation needs adaption: Tropical Forestry and climate change. Mitigating Adaptive Strategies for Global Change 2008\n \n '},{id:"B16",body:'\n \n \n \n Hemmati\n M\n \n Multi-Stakeholder Processes for Governance and Sustainability, Beyond Deadlock and Conflict, London: Earthscan; 2002\n \n '},{id:"B17",body:'\n \n \n \n Houghton\n J. T\n \n \n Ding\n Y\n \n \n Griggs\n D. J\n \n \n Noguer\n M\n \n \n Van Der Linden\n P. J\n \n \n Dai\n X\n \n \n Maskell\n K\n \n \n Johnson\n C. A\n \n\n Climate change 2001: The scientific basis. 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Forest@ 2012;9\n 1\n 1\n 7\n http://www.sisef.it/forest@/contents/?id=688accessed 5 April 2012\n \n '},{id:"B27",body:'\n \n \n \n Price\n M. F\n \n et al\n Mountain Forests in a Changing World- Realizing Values, addressing challenges. Rome: FAO/MPS and SDC; 2011\n \n '},{id:"B28",body:'\n \n \n \n Roetzer\n T\n \n Climate change, stand structure and the growth of forest stands. Annalen der Meteorologie 2005\n 40\n 43\n \n '},{id:"B29",body:'\n \n \n \n Somlai\n I. G\n \n Identifying stakeholders: Approach to Social Forestry Conflicts. International Journal of Social Forestry 2008\n 83\n 95\n \n '},{id:"B30",body:'\n \n \n \n Spittlehouse\n D. L\n \n \n Stewart\n R. B\n \n Adaptation to climate change in forest management. BC Journal of Ecosystems and Management 2003\n 1\n 11\n \n '},{id:"B31",body:'\n \n \n \n Sterman\n J. D\n \n Learning in and about complex systems. 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Nairobi: United Nations Environment Programme; 2011. www.unep.org/greeneconomyaccessed 15 April 2012\n \n '},{id:"B36",body:'\n \n \n \n Williams\n M\n \n Deforesting the Earth: From Prehistory to Global Crisis, An Abridgment. Chicago: University of Chicago Press; 2006p xviii and 543.\n '},{id:"B37",body:'\n \n \n \n Zierl\n B\n \n \n Bugmann\n H\n \n Sensitivity of carbon cycling in the European Alps to changes of climate and land cover. Climatic Change 2007\n 195\n 212\n \n '}],footnotes:[],contributors:[{corresp:null,contributorFullName:"Luca Cetara",address:null,affiliation:'
Istituto per le Piante da Legno e l’Ambiente – IPLA, Torino, Italy
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1. Introduction
Whereas the genera of great apes are known to differ strongly among each other in their social structure, the small apes or gibbons clearly are a more uniform group [1, 2, 3]. Distributed in Asian rain forests, its members typically live in socially monogamous, unimale unifemale, territorial groups [4, 5], although some flexibility in group composition and sexual behavior occurs [6, 7, 8]. Non-monogamous (extra-pair) matings and groups with multiple adult males and multiple adult females occasionally occur in gibbons [7, 9, 10, 11, 12, 13, 14, 15].
It has repeatedly been suggested, however, that gibbon taxa may differ in subtle details of their social organization [16]:
Wild family groups of Malayan siamangs (Symphalangus syndactylus) appear to be more tightly knit than those of white-handed gibbons (Hylobates lar), with siamang intra-group distances being shorter and intra-group communicatory signals being fewer or less conspicuous to observers, and paternal infant-carrying only occurring in siamangs [17, 18, 19, 20, 21]. A greater heterosexual cohesion in pair bonds of siamangs, as compared to white-handed gibbons, was also found in a field study in Sumatra [22], but differences in paternal investment appear to be less clear-cut. Paternal infant-carrying appears to be absent in some wild and many captive siamang groups and varies dramatically among males of the same population [10, 23, 24, 25], while it may occasionally occur in other gibbon taxa, at least in captive groups [23, 26].
Several reports suggest that the black-cheeked species of the crested gibbons (genus Nomascus) differ from other hylobatids in their social organization by more often forming bi-female groups [27, 28, 29, 30, 31, 32, 33]. This may not appear to apply to light-cheeked crested gibbon species [34, 35], but see [36].
Recent studies on gibbon calls documented that the various taxa strongly differ in how they present their long and loud morning song bouts [37, 38, 39, 40]. In some taxa, mated pairs produce duet song bouts but usually no solo songs (genera Hoolock, Nomascus and Symphalangus), others produce sex-specific solo songs in addition to duets (Hylobates agilis, H. lar, H. muelleri, H. pileatus), and others yet produce sex-specific solo song bouts only (H. klossii, H. moloch). In all members of the genus Nomascus and most species of the genus Hylobates, for instance, most of the singing is produced by males, whereas in H. moloch, males sing rarely and most songs are produced by females. This pronounced diversity of sex-specific investment in resource defense provides indirect evidence for taxon-specific differences in social organization, and, possibly, in previously unrecognized factors of ecological adaptation or inter-specific competition.
Moreover, duets strongly differ in their complexity among taxa, with the most complex ones being uttered by siamangs (S. syndactylus) [41, 42]. These differences in song organization also strongly suggest differences in social organization. Because duet song bouts are believed to serve, among other things, to strengthen or advertise pair bonds, duetting and non-duetting gibbon species should differ either in their pair bond strength or in how the pair bond strength is achieved [43, 44].
Although the reports cited above suggest that some gibbon taxa may differ in social organization, very little quantitative evidence for such species-specific differences in the social structure are currently available. Previous comparisons have been limited to sample sizes of 2–3 pairs per genus [17, 19, 22, 23], thus precluding statistical testing. Palombit [3] correctly identified a great need for detailed data on more hylobatid pair bonds, so that we may identify consistent social patterns in light of intra-specific variation.
Early reviews on monogamy found shared behavioral traits in monogamous primates and suggested that the males generally initiate grooming and groom females more often than the reverse situation occurs [45]. In socially monogamous pairs, pair partners usually maintain close spatial association and often perform spectacular, well-coordinated, pair-specific display behavior. This does not necessarily imply, however, that the sexes share mutual socioreproductive interests [46]. Shared interests may be not be required for the evolution of social monogamy, and pair formation does not require an absence of sexual conflict, or symmetric costs and benefits for males and females.
Several of the hypotheses explaining the evolution and maintenance of social monogamy in mammals make predictions regarding female and male contributions to the pair bond [47].
According to the ‘resource-defense hypothesis’, both a male and a female benefit from pair bonding to defend resources together [48]. In this case, a male and a female should be equally interested in maintaining proximity and affiliation with a pair mate and defending their territory.
According to the ‘mate-defense hypothesis’, a male should bond with a female when either the spatial distribution of females or the temporal distribution of fertile periods makes it difficult for males to defend access to more than one female at a time [49]. In this case, a male should be more interested in maintaining proximity and affiliation with the partner.
According to the ‘male-services hypothesis’, a female benefits from bonding with a male when the male provides important services such as territorial or antipredator defense, infant care, or protection from infanticide by competing males [48, 50, 51, 52]. In this case, a female should to be more interested in maintaining proximity and affiliation with the partner while the male should provide some significant services.
The goal of our study was to answer the following two questions: (1) Do gibbon taxa differ in the strength of their pair bonds? (2) Do gibbon taxa differ in the way pair bonds are created and maintained?
We present the first comparative and quantitative study on differences of the pair bond among multiple gibbon taxa. We have collected observational data on several captive groups of siamangs (genus Symphalangus), three species of the crested gibbons (genus Nomascus), and the pileated gibbon (Hylobates pileatus) as a representative of the dwarf gibbons (genus Hylobates). Our study will focus, therefore, on a comparison of these three genera. Photographs of three of the species we studied are shown in Figure 1. In addition, a compilation of previously-published data also permits us to make a limited comparison with other gibbons of the genus Hylobates.
Figure 1.
Three of the gibbon species that were observed during this study. (a) Siamang (Symphalangus syndactylus), family group, showing from left to right: juvenile, adult male, and adult female carrying an infant. Siamangs are of mostly blackish fur coloration. Notice the half-inflated throat sacs, which play a role in siamang territorial vocalizations and can be inflated to about the size of the animals’ head. (b) Northern White-cheeked Crested Gibbon (Nomascus leucogenys) pair, showing from left to right: adult female, and adult male. Adult male and female differ markedly in their fur coloration. Females are mostly yellowish, and males are blackish. (c) Pileated Gibbon (Hylobates pileatus) family group, showing from left to right: adult female carrying a neonate infant, adult male, subadult male, and juvenile male. Adult male and female of this species also differ markedly in their fur coloration. Females are pale grey or fawn-buff with black on crown, cheeks and chest, while males are blackish with white facial border, corona, digits, and genital tuft. Photographs by Thomas Geissmann.
In order to estimate pair bond strength, we quantified the following three generally-accepted indicators of pair bond strength (behavioral synchronization, relative distance between mates, and amount of partner directed grooming) following [44, 53].
In order to gain insight in the pair bonding mechanism, we examined which sex invests more in the pair bond by measuring the amount of grooming directed at the respective partner.
Although allogrooming per se may serve hygienic, social, communicatory, stress relief or thermal functions [54, 55, 56, 57, 58, 59], these functions may be influenced by a species’s social organization. For social systems with stable pair structures, allogrooming has been proposed to serve a pair-bonding function [45, 60, 61] and to reflect the investment into a pair bond [62, 63] and, therefore, the ultimate costs and benefits which partners can expect from a relationship [64]. Thus, sex-specific differences in partner-directed allogrooming indicate – on a proximate level – ultimate sex-specific strategies.
2. Methods
Our data collection methods have previously been described [44, 53]. Siamang (Symphalangus syndactylus) data were collected in a consistent form by one of us (M.O.) between April 1985 and March 1993. A total of 17 siamang groups were observed at the following zoos: Antwerp (An), Belgium, Branféré (Br1, Br2, Br3), France, Budapest (Bu), Hungary, Berlin Zoo (Be), Dortmund (Do), Dresden (Dr1, Dr2), Duisburg (Du), Frankfurt (Fr), Krefeld (Kr1, Kr2), Munich (Mn), Germany, Studen (St), Zurich (Zh), Switzerland and Washington (Wa), U.S.A., with group size ranging from two to six animals.
Crested gibbon data were collected in the same way by S.R.-W. between August and October 2001. A total of seven crested gibbon groups (Nomascus) were observed at the following zoos: Duisburg (Du), Eberswalde (Eb), Osnabrück (Os1, Os2), Germany, and Mulhouse (Mu1, Mu2, Mu3), France, with group sizes ranging from two to five animals. Three crested gibbon species are represented in our sample, including the Northern White-cheeked Crested Gibbon (N. leucogenys): Du, Mu1 and Os2; the Southern White-cheeked Crested Gibbon (N. siki): Mu2; and the Southern Yellow-cheeked Crested Gibbon (N. gabriellae): Eb, Mu3 and Os1. The gibbon classification used here follows [65].
Data for Pileated Gibbons (Hylobates pileatus) were collected in the same way by J.v.d.L. and K.N between February and May 2007. A total of nine groups were observed at the following zoos: Phnom Tamao, Cambodia (PT1–7), and Zurich, Switzerland (Zu1, Zu2), with group size ranging from two to five animals.
In order to assure comparability of data collected by the observers M.O., S.R., J.v.d.L. and K.N., dual observations were carried out on 31 July 2001 and on 13 February 2007, respectively, until consistent values of inter-observer concordance were obtained [66].
At each zoo, observation time for each sampling method was distributed evenly across the animals’ activity period between 0700 and 1800 h (until 1700 h during the winter months, and between 0800 and 1800 h for crested gibbon groups Du, Eb, Mu, Os2).
We used focal animal sampling with the continuous recording rule [66, 67, 68, 69] to collect information on the frequency and duration of grooming behavior between mates. Focal animals were changed every 20 min. Each of 11 siamang pairs was observed for 80 h, except for pairs Mu (50 h) and Du (90 h), and each crested and pileated gibbon pair for 35 h. Grooming occurred in discrete sessions that could be counted. We allowed an interval of up to 10 seconds between bouts of grooming before we counted them as two sessions, rather than one.
We used scan sampling to record behavioral synchronization of activities between mates. We defined 11 behavioral categories: socio-positive behavior (including allogrooming, embracing) and infant care, play, agonistic, territorial, sexual, comfort-related, feeding and food-related behavior, observe, rest and sleep, excretion, and locomotion. Scans were made every 1 min (or every 2 min in siamang groups Dr1, Kr1, Kr2, St). Siamang pairs were scanned for synchronization of behavioral categories during blocks of 5 or 10 min, separated by intervals of 20 min. Crested and pileated gibbon pairs were scanned for synchronization in parallel to the focal animal observations of grooming behavior. Each of 13 siamangs pairs was observed for 20 h, except pairs Zu (15 h), Be and Fr (30 h), and Du (40 h). Each crested and pileated gibbon pair was observed for 35 h. The occurrence of synchronized behavior between pair-mates is expressed in % of the total number of scans for a given pair.
We also used scan sampling to record the distance between mates. Distances were recorded to an accuracy of 0.5 m. If the individuals were closer to each other than 0.5 m, we recorded distance according to the following definitions: 0.3 m: shortest distance without body contact, 0.2 m: body contact through extremities, 0 m: body contact through trunk. Siamang pairs were scanned during blocks of 10 min, separated by intervals of at least 10 min. During each scan sampling block, distance was recorded every 10 s. Crested and pileated gibbon pairs were scanned for the distance between mates every 1 min, and scans were carried out in parallel to the focal animal observations of grooming behavior. Each of 17 siamangs pairs was observed for 10 h, except pairs BrA, Bu, DrA (20 h), Be, Du, KrA (30 h), and Fr (210 h). Each crested and pileated gibbon pair was observed for 35 h.
The size of the enclosure varied between zoos (some gibbon groups were held in cages, others on islands). In small cages, the cage walls set outer limits to the inter-individual distances. Because small cages may have forced our pairs into closer proximity than bigger enclosures, we did not directly use absolute inter-individual distances in our comparisons. Instead, we calculated the relative distance (%) between mates, i.e. the inter-individual distance relative to the maximal possible distance in the pair’s given environment (cage or island). This method was described by [44]. In order to test whether cage size had an influence on pair bonding behavior, we used the maximal possible distance in the pair’s given environment as an indicator of cage size. In siamangs, our largest sample, this value ranged from 5.7 m in the smallest cage to 43.5 m on the largest island. We arbitrarily defined cages with values of less than 10 m as “small enclosures”, the others as “large enclosures”.
In addition to determining relative distance, we used scan sampling to estimate the time pair partners spent in each of the following distance classes: 1: body contact or distance of less than 0.3 m, 2: 0.3–1 m, 3: >1 m–3 m, 4: >3 m.
For comparison of our data on partner-directed behavior with literature data, we used male and female proportions of these behavioral variables, where male and female proportions complement each other to 100%. Proportions should be independent of the observation method and permit comparison of data from different observers.
One-sample sign test tests were used to compare classes of sex-specific grooming proportions within genera. For comparison of data among three genera, we used Kruskal-Wallis tests with Dunn’s post hoc tests [70]. In order to compare data between H. pileatus and H. lar (i.e. after inclusion of data compiled from the literature), we used the Mann–Whitney U tests [71]. All tests were two-tailed, and the null hypothesis was rejected at P = 0.05. Statistical were calculated using the software StatView 5.0.1 and SPSS 17.0 on a Macintosh G4 computer.
3. Results
3.1 Strength of pair bonds
3.1.1 Synchronization of behavioral variables
The average degree of behavioral synchronization across 11 behavioral variables is shown in Figure 2. Values range from 15.5% to 63.9% in siamangs, from 8.0% to 38.7% in crested gibbons, and from 19.2% and 42.7%. As shown in Table 1, however, the overall degree of behavioral synchronization does not differ significantly between the genera (Kruskal-Wallis test, P = 0.186).
Figure 2.
Comparison of the average degree of behavioral synchronization between siamangs (Symphalangus, N = 13 pairs), crested gibbons (Nomascus, N = 7 pairs), and pileated gibbons (Hylobates pileatus, N = 9 pairs). Box plots show mean values, standard deviations and minimum and maximum values. The difference between the genera is not statistically significant (Kruskal-Wallis test, P > 0.05, see text).
Taxon
Kruskal- Wallis test (p)
Symphalangus
Nomascus
Hylobates pileatus
Taxon mean
35.02 ± 15.39 (N = 14)
23.73 ± 11.30 (N = 7)
32.69 ± 7.95 (N = 9)
0.186
Table 1.
Average degree of synchronization [% ± standerd deviation] across 11 behavioral variables for siamangs (Symphalangus syndactylus), crested gibbons (Nomascus spp.), and pileated gibbons (Hylobates pileatus). Abbreviation: p = error probability.
3.1.2 Relative partner-distance
Average relative partner distances and time proportions spent in four distance classes for each study group are listed in Table 2. Considerable differences were found among pairs. Time spent in distance class 1, for instance, varies from 0.3% to 49.7% in siamangs, from 5.6% to 32.3% in crested gibbons, and from 0.0% to 20.5% in pileated gibbons. Similarly, time spent in distance class 4 varies from 1.3% to 61.2% in siamangs, from 14.1% to 47.4% in crested gibbons, and from 31.6–84% in pileated gibbons. The time gibbon pairs spent in each of the four partner distance classes are shown in Figure 3. The three taxa do not differ significantly among each other in the time groups spent in any of the four partner distance classes (Kruskal-Wallis tests, P > 0.05), except for time spent in distance class 4 (P = 0.014). Dunn post-hoc tests revealed that pileated gibbon pairs spent more time in distance class 4 than siamangs (P < 0.02). Moreover, the difference in distance class 2 is close to significance (P = 0.051).
Group
Relative distance
Distance classes [%]
[%]
1
2
3
4
(a) Siamangs
Antwerp
32.80
11.90
14.00
50.00
24.10
Berlin Zoo
29.80
13.70
10.00
40.80
35.50
Branféré 1
14.50
5.40
19.50
31.20
43.90
Branféré 2
12.10
10.30
29.70
23.90
36.10
Branféré 3
18.30
1.80
17.00
20.00
61.20
Budapest
29.30
10.70
21.10
34.10
34.10
Dortmund
10.10
29.50
34.80
16.60
19.10
Dresden 1
29.00
12.50
18.10
67.50
1.90
Dresden 2
24.00
12.90
31.10
54.70
1.30
Duisburg
29.10
12.30
12.20
48.70
26.80
Frankfurt
40.40
3.30
12.60
62.30
21.80
Krefeld 1
30.90
3.50
15.10
37.60
43.80
Krefeld 2
35.90
0.30
7.40
38.60
53.70
Munich
31.20
24.90
13.80
16.20
45.10
Studen
11.50
49.70
22.40
19.30
8.60
Washington
26.50
20.50
14.90
21.40
43.20
Zurich
36.10
1.30
17.80
62.30
18.60
Mean
25.97
13.21
18.32
37.95
30.52
(b) Crested gibbons
Duisburg
33.68
5.70
39.19
41.04
14.07
Eberswalde
12.12
32.30
17.01
15.68
35.01
Mulhouse 1
30.40
7.65
19.52
25.40
47.42
Mulhouse 2
23.31
23.68
14.33
15.85
46.14
Mulhouse 3
21.12
30.73
14.79
17.03
37.45
Osnabrück 1
21.99
17.80
16.22
24.09
41.89
Osnabrück 2
21.63
5.64
30.05
27.01
37.30
Mean
23.47
17.64
21.59
23.73
37.04
(c) Pileated gibbons
Phnom Tamao 1
28.77
7.30
14.20
28.20
50.30
Phnom Tamao 2
7.28
10.70
17.70
17.70
54.40
Phnom Tamao 3
41.99
0.00
3.90
11.30
84.80
Phnom Tamao 4
23.18
20.50
6.00
28.90
44.60
Phnom Tamao 5
24.58
11.30
16.70
23.60
48.40
Phnom Tamao 6
12.82
13.80
11.20
26.40
48.50
Phnom Tamao 7
23.13
5.50
9.70
53.20
31.60
Zurich 1
18.29
14.90
20.10
24.70
40.40
Zurich 2
34.83
0.90
7.40
17.20
47.50
Mean
23.47
9.43
11.88
25.69
50.06
Table 2.
Average relative partner distances and time proportions spent in four distance classes: (a) siamangs (Symphalangus syndactylus, N = 17 groups), (b) crested gibbons (Nomascus spp., N = 7 groups), (c) pileated gibbons (Hylobates pileatus, N = 9 groups).
Figure 3.
Time proportion spent in 4 distance classes (left) and of the mean relative partner distances (right) in siamangs (Symphalangus, N = 17 pairs), crested gibbons (Nomascus, N = 7 pairs), and pileated gibbons (Hylobates pileatus, N = 9 pairs). Box plots show mean values, standard deviations and minimum and maximum values. In a comparison between the genera (Kruskal-Wallis tests), only one of the five variables (distance class 4) are statistically significant (P < 0.05, see text).
The relative distance between pair partners is also shown in Figure 3. The three taxa do not differ in this variable (Kruskal-Wallis test, P > 0.05).
3.1.3 Allogrooming
The number of grooming sessions/hour (average of male and female) varies from 0.0 to 3.9 in siamangs (Symphalangus, N = 12 pairs), from 0.5 to 2.0 in crested gibbons (Nomascus, N = 7 pairs), and from 0.0 to 2.1 in pileated gibbons. The difference is not statistically significant (Kruskal-Wallis test, P > 0.05). The average duration of grooming sessions varies from 0 s to 76.0 s in siamangs, from 50.5 s to 132.1 s in crested gibbons, and from 0 s to 101.0 s in pileated gibbons. This difference is not statistically significant (Kruskal-Wallis test, P > 0.05). The proportion of time spent grooming varies from 0% to 66.9% in siamang pairs, from 9.3% to 28.7% in crested gibbon pairs, and from 0% to 57.7% in pileated gibbons. The difference is not statistically significant (Kruskal-Wallis test, P > 0.05). As a result, siamang pairs, crested gibbon pairs, and pileated gibbon pairs spend similar amounts of time grooming (Figure 4).
Figure 4.
Average intra-pair grooming frequency per hour, mean duration of grooming sessions, and proportion of time spent grooming in siamangs (Symphalangus, N = 11 pairs), crested gibbons (Nomascus, N = 7 pairs), and pileated gibbons (Hylobates pileatus, N = 9 pairs). Box plots show mean values, standard deviations and minimum and maximum values. In a comparison between the genera (Kruskal-Wallis tests), none of the three variables are statistically significant (P > 0.05, see text).
3.2 Mechanism of pair bonds
In order to study which sex invested more in maintaining the pair bond, we determined the %-proportion of partner-directed grooming for each adult. Because male and female proportions in a pair complement each other to 100%, the grooming proportion of one sex will suffice to provide the full information. The results are summarized in Figure 5.
Figure 5.
Average male-female proportions of intra-pair grooming frequency per hour, mean duration of grooming sessions, and time spent grooming in siamangs (Symphalangus, N = 10 pairs), crested gibbons (Nomascus, N = 7 pairs), and pileated gibbons (Hylobates pileatus, N = 8 pairs). Box plots show mean values, standard deviations and minimum and maximum values. In a comparison between the genera (Kruskal-Wallis tests), all three variables are statistically significant (P < 0.05, see text). Abbreviations: M = males, F = females.
In these analyses, one pair of siamangs (Kr2) and one pair of pileated gibbons (PT3) had to be excluded because pair partners were not observed to groom each other at all and male–female proportions of grooming variables could, therefore, not be calculated. Neither Kr2 nor PT3 were newly formed pairs, and the reason why no grooming occurred among pair partners is unknown.
Male proportions in the number of grooming sessions per hour varied from 8.5% to 78.3% in siamangs, from 2.9% to 62.5% in crested gibbons, and from 0.0% to 85.4% in pileated gibbons. The difference between the genera is statistically significant (Kruskal-Wallis test, P = 0.032). The Dunn post-hoc test revealed no significant pair-wise differences, but as a trend, male proportions were higher in siamangs than in pileated gibbons (P < 0.1). Male proportions in grooming session duration varied from 26.7% to 74.6% in siamangs, from 16.6% to 68.2% in crested gibbons, and, and from 0.0% to 48.0% in pileated gibbons. The difference between the genera is statistically significant (Kruskal-Wallis test, P = 0.043), and the Dunn post-hoc test revealed that male proportions were higher in siamangs than in pileated gibbons (P < 0.05). Male proportions in the time spent grooming varied from 3.3% to 90.4% in siamangs, from 0.9% to 69.1% in crested gibbons, and from 0.0% to 84.3% in pileated gibbons. The difference between the genera is statistically significant (Kruskal-Wallis test, P = 0.035), and the Dunn post-hoc test revealed that male proportions were higher in siamangs than in pileated gibbons (P < 0.05). As a result, siamang males groom partners in longer sessions and spend more time grooming them than pileated gibbon males. Only as a trend, siamang males also tend to groom their partners during more grooming sessions than pileated gibbons.
In addition to the grooming data collected by focal animal sampling, we also collected data on male–female grooming proportions for three additional siamang groups (An, Be, Zu) during the scan sampling observations. Male grooming proportions in these groups amounted to 95.4%, 85.7% and 100%, respectively.
Finally, we compiled data from the pertinent literature on other gibbon groups. If several reports were available on the same group, we used the study with the larger data base. These data are summarized in Table 3 and also includes members of the dwarf gibbons (Hylobates) and hoolock gibbons (Hoolock) other that the species observed by us. The sample size for the hoolocks (Table 3d), however, comprises only three groups and is too small for statistical analysis. Pairs that did not exhibit partner-directed grooming are also excluded from the analysis. Our resulting sample comprises 76 pairs. For summary statistics, we split male grooming contribution evenly into three classes: (1) 0–33%, (2) >33–66%, (3) >66%. Pairs should be evenly distributed across these classes if male and female contributions were balanced. As shown in Table 3, this is not the case in siamangs (N = 28). Most pairs fall into class 3, suggesting that siamang males, as a rule, provide most of the intra-pair grooming. In crested gibbons (N = 22) and dwarf gibbons (N = 26), the situation is exactly reversed. Most pairs fall into class 1, indicating that females provide most of the intra-pair grooming in Nomascus and Hylobates. The difference from the expected value of 50% is statistically significant for the genera Nomascus and Symphalangus (One-sample sign test, P = 0.002, and P = 0.013), but not for Hylobates (One-sample sign test, P > 0.05). As indicated by the species labels in Figure 6c, the distribution appears to differ among species of the genus Hylobates. Whereas partner-directed grooming is mainly provided by females in H. pileatus (N = 11), the distribution appears to be more randomly distributed in H. lar (N = 11). Although the difference between the two species is statistically significant (Mann–Whitney U test, P = 0.032), the samples are relatively small and the result should be regarded with caution. If only H. pileatus is considered, the difference from the expected value of 50% is still not significant (One-sample sign test, P > 0.05), but the sample is very small in this case (N = 11).
Male contributions (%) to intra-pair grooming in gibbons. Classes of male grooming proportion are defined as (1) 0–33%, (2) >33–66% and (3) >66%. Abbreviations: Hoolock: Hho = H. hoolock; Hylobates: Hag = H. agilis, Hla = H. lar, Hmo = H. moloch, Hpi = H. pileatus. Nomascus: Nco = N. concolor, Nga = N. gabriellae, Nle = N. leucogenys, Nsi = N. siki. Captive/wild: c = captive, w = wild. Data type: f = frequency, t = time. Grooming: – = no partner-directed grooming observed. Source: ts = this study.
Figure 6.
Male contributions to intra-pair grooming in gibbons. (a) Siamangs (Symphalangus, N = 28 pairs); (b) crested gibbons (Nomascus, N = 18 pairs); (c) dwarf gibbons (Hylobates, N = 23 pairs); (d) hoolock gibbons (Hoolock, N = 3 pairs). Abbreviations in (c) identify the following species: a – H. agilis, l – H. lar, m – H. moloch, and p – H. pileatus.
Especially in siamangs and crested gibbons, the unilateral distribution of male grooming proportion is surprisingly consistent. We wondered whether there was something about the pairs which do not exhibit consistent results. Of the gibbons we observed, only the siamang sample was large enough to test several potential influences statistically. In the 16 siamang pairs that showed grooming, “Having infants” had no influence on the proportion of male grooming (Mann–Whitney U test, 16 pairs, U = 15.5, P > 0.05). However, “Having a family group” did: Pairs without a family showed a smaller proportion of male grooming than pairs with offspring in the family (Mann–Whitney U test, 16 pairs, U = 11.0, P = 0.03). We also wondered whether there were any differences between pairs kept in smaller cages and pairs kept in bigger enclosures. In order to study the effect of cage size on the male proportion of pair-grooming in siamang pairs, we used the maximal possible distance in the pair’s given environment as an indicator of cage size. We compared male grooming proportion between siamangs kept in small enclosures (N = 9 groups) to siamangs kept in large enclosures (N = 7 groups). The difference was not statistically significant (Mann–Whitney U test, P > 0.05). The correlation between cage size and male grooming proportion was also not significant (Spearman rank correlation, Rho = −0.165, P > 0.05).
Results for the dwarf gibbons are less consistent than those for siamangs or crested gibbons (Table 3). Could the differences within the first two genera be influenced by wild vs. captive gibbons? In siamangs, captive pairs did not differ from wild ones (Mann–Whitney U-test, 23 captive pairs vs. 5 wild pairs, U = 51.0, P > 0.05). In dwarf gibbons, on the other hand, captive pairs differ significantly from wild ones (Mann–Whitney U test, 20 captive pairs vs. 6 wild pairs, U = 24.0, P = 0.027). It should be noted, however, that all available data for wild dwarf gibbons stem from only one species (H. lar), whereas several other species are represented in the captive sample of the same genus. If the comparison is restricted to Hylobates lar, the difference is not statistically significant (Mann–Whitney U test, 5 captive pairs vs. 6 wild pairs, U = 8.0, P > 0.05). Therefore, the variability of male grooming proportion among dwarf gibbons may be influenced by, and differ among, the species.
The frequency distribution of male grooming proportion is shown in Figure 6. These data differ significantly among the genera (Kruskal-Wallis test, df = 2, P < 0.0001). As revealed by the Dunn post-hoc tests, the male proportion in partner grooming is significantly higher in Symphalangus than in both Nomascus (P < 0.001) and Hylobates (P < 0.005), whereas no differences were found between Hylobates and Nomascus (P > 0.05).
4. Discussion
Monogamy is common among birds [95], but established in only about 3–9% of all mammals and about 15–29% of all primate species [45, 48, 96]. Among hominoid apes, only gibbons typically live in social monogamy (in the sense of [46]).
Various hypotheses explaining the proximate and ultimate mechanisms, which led to the evolution of social monogamy among gibbons are under debate [48, 97, 98, 99]. In these discussions, monogamy among gibbons is usually treated as, and implicitly assumed to be, a comparable, uniform entity. Cowlishaw [100], for instance, assumes that the pair bond is created by the different resource interests of the partners. The female is interested in the territory and the food resources in it, whereas the male is interested in the female partner.
Although several reports suggested that gibbon taxa might exhibit subtle distinctions in their group coherence or group composition (see Introduction), quantitative data for representative numbers of pairs have been lacking. It is generally assumed that pair bonds in all gibbon taxa are built up and maintained in the same way, and that males are mainly responsible for maintaining the pair bonds [3, 52].
As will be discussed below, this study provides evidence to the contrary. We compared indicators of pair bond strength and sex-specific pair bond investment between 7 pairs of crested gibbons, 9 pairs of pileated gibbons, and 11–17 pairs of siamangs (depending on the variable in question).
4.1 Pair bond strength
We determined three variables to compare pair bond strength between siamangs and crested gibbons (synchronization of behavioral variables, relative partner-distance, and allogrooming).
Synchronization of behavioral variables: The overall degree of behavioral synchronization does not differ significantly among the genera, suggesting that they do not differ in the strength of the pair bond as expressed by behavioral synchronization.
Relative partner-distance: The three gibbon taxa did not differ in the time spent in any of the four partner distance classes, except that siamang pairs spent less time in the largest distance class 4 (>3 m) than pileated gibbon (H. pileatus) pairs, suggesting that pair bond strength in siamangs may be more pronounced than in pileated gibbons. Similarly, Palombit [22] found that siamang pairs spent significantly more time in close proximity to one another than white-handed gibbons (H. lar). However, we found no significant differences in the other distance classes or in the mean relative distance between pair partners.
Allogrooming: The three gibbon taxa did not differ in the number of grooming sessions/hour (average male and female), the proportion of time spent grooming, and the average duration of grooming sessions. As a result, siamang pairs, crested gibbon pairs and pileated gibbon pairs are involved in similar numbers of grooming sessions and spend similar amounts of time grooming.
In summary, pileated gibbons appear to spend more time apart by the largest distance class than siamangs. Based on this variable alone, their pair bond may be weaker than that of siamangs. No consistent differences in pair bond strength were found between siamangs and crested gibbons or between crested gibbons and pileated gibbons.
4.2 Pair bond maintenance
We examined which sex invests more in the pair bond by measuring the amount of grooming directed at the respective partner. For simplicity, we indicate the male proportion only; the female partner’s proportion is its complement to 100%.
Our results show that in pileated and crested gibbon pairs partner-directed grooming is mostly provided by females, whereas males are the main groomers in siamang pairs. This result is further supported by additional data we collected from the literature. In most siamang pairs, males are the main groomers. Furthermore, male proportion in grooming session duration and time spent grooming are higher in siamangs than in pileated gibbons, whereas the male proportions in the numbers of grooming sessions per hour do not differ between siamangs and pileated gibbons. Siamang males groom their partners more often than crested gibbon males do, but time spent grooming and male proportion in duration of grooming do not differ between siamangs and crested gibbons. Our pairwise comparison revealed statistically significant differences for Symphalangus/Nomascus, but not for Symphalangus/Hylobates or Hylobates/Nomascus.
These results suggest that each genus differs in the mechanism of how pair bonds are created or maintained. Especially siamangs differ compared to pileated and crested gibbons: male-driven in the former, female-driven in the latter two. Obviously, the pair bond in gibbons does not appear to be a uniform entity. Date compiled in Table 3 also suggest that field and zoo observations are consistent (except that only one wild pair exhibits a “Class 1” male grooming proportion of 0–33%).
Our results support vocal and molecular studies suggesting that gibbons are a much less homogenous group than generally assumed [39, 101, 102]. It is becoming more and more obvious that including one gibbon taxon into comparative studies in order to represent “the gibbon” is not useful practice anymore.
In our overall sample of dwarf gibbon pairs (Hylobates, N = 26) as well as in the subset of H. pileatus-pairs (N = 11), females provided more partner-grooming than males in most pairs. In H. lar-pairs (N = 11), on the other hand, the amount of grooming provided by males and females was very variable (Table 3) and the reason for this variability in this sample is not clear.
Kleiman [45] proposed that males should be the more active groomers in monogamous primates because their dominance situation is reversed as compared to primates with polygynous social organizations. Simple dominance relationships, however, do not seem the only variables influencing partner-directed allogrooming in gibbons.
If partner-directed allogrooming reflects the investment into a pair bond [62, 63], then our results document that the readiness to invest differs among pairs. In most (but not necessarily all) pairs, both partners appeared to be interested in maintaining the pair pond, and both partners provided at least some allogrooming. In addition to individual differences, the interest in a pair partner may vary with time. Probably, the benefit of a pair bond is related to the reproductive potential of a partner. Observations on wild H. lar and H. moloch suggest that the reproductive status of females may play an important role [13, 103, 104]. Males may have a higher interest to invest into the pair bond with females when they are receptive, in order to guard them more efficiently, copulate more frequently and improve the probability of their paternity. If partner-directed grooming is part of a mate-guarding strategy with fluctuating relevance to the groomer, it becomes clear why data of relatively large numbers of pairs need to be compared in order to discover species-specific differences.
How do our findings compare to the predictions of the three hypotheses for the evolution of pair bonds presented in the Introduction?
The ‘male-services hypothesis’ predicts that a female will invest substantially in a social relationship with a male willing to assume the costs of territorial or antipredator defense, infant care or protection from infanticidal males. This should result in females investing more than males in maintaining the pair bond. This prediction is met by our samples of crested gibbons (N = 22 pairs, Table 3), pileated gibbons (N = 11 pairs) and the combined sample of all dwarf gibbons (N = 26 pairs). In all three samples, females were the main groomers in most pairs.
The ‘mate-defense hypothesis’ predicts that bonding with a female is beneficial for a male when either the spatial distribution of females or the temporal distribution of fertile periods makes it difficult for the males to defend access to more than one female at a time. This should result in males investing more than females in maintaining the pair bond. This prediction is met by our sample of siamangs (N = 28 pairs), where males were the main groomers in most pairs.
The ‘resource-defense hypothesis’ predicts that both a male and a female benefit from pair bonding to defend resources together. This should result in a male and a female being equally interested in maintaining proximity and affiliation with a pair mate and defending their territory. None of the gibbon samples of this study appears to meet this prediction.
Only very limited information on the direction of partner-grooming is available for the fourth of the gibbon genera, the hoolocks (genus Hoolock). Ahsan [105], who studied three groups of the western hoolock gibbon (H. hoolock) at two sites in Bangladesh, reported that grooming was most frequent between adult pairs and that it was “mostly performed by the adult male”. Unfortunately, the author did not publish the quantitative data in support of his statement. Sankaran [94] observed three groups of the same species in the Gibbon Wildlife Sanctuary in Assam. However, none of his males provided more than 50% of the partner-grooming (Table 3). Apparently, the results of the two studies differ, but the overall sample size is too small to assess the directionality of partner grooming in hoolock gibbons with any reliability.
It has also been reported that allogrooming between pair mates is virtually nonexistent in wild Hylobates agilis [21] and H. klossii [106], in contrast to the situation in wild H. lar and siamangs [10, 13, 19, 103]. This suggests that the range of variation in gibbon pair bonds may be larger than what we covered in our study. Several species of dwarf gibbons (Hylobates) are hardly represented or not represented at all in our data, including H. agilis and H. klossii.
Within crested gibbons (Nomascus), most of our data are from one species, N. leucogenys (N = 14 pairs), whereas few pairs of other light-cheeked species and only one male of a black-cheeked species (N. concolor in a mixed pair) are available.
5. Conclusions
A comparison of pair bond strength in three gibbon taxa – siamangs (Symphalangus), crested gibbons (Nomascus) and pileated gibbons (Hylobates pileatus) revealed a difference in relative partner distances between siamangs and pileated gibbons, suggesting that siamangs may have a stronger pair bond than pileated gibbons. No difference between the three taxa was found in other variables believed to indicate pair bond strength: degree of behavioral synchronization and amounts of grooming (both numbers of events and actual grooming time).
This study provides the first statistically significant evidence that the mechanisms of how pair bonds are created or maintained, differ between gibbon taxa. As indicated by the amount of partner-directed grooming, siamang males invest significantly more into the pair bond than females, whereas the opposite is true in crested gibbons, pileated gibbons, and an enlarged sample of dwarf gibbons (genus Hylobates). Additional species-specific differences may, however, occur within the latter group, with partner-grooming investment being highly variable in H. lar.
Our results for crested gibbons, pileated gibbons, and a combined sample of dwarf gibbons correspond to predictions derived from the ‘male-services hypothesis’ for the evolution of pair bonds. According to this hypothesis, a female will invest substantially in a social relationship with a male willing to assume the costs of territorial or antipredator defense, infant care or protection from infanticidal males.
In contrast, our results for siamangs correspond to predictions derived from the ‘mate-defense hypothesis’. According to this hypothesis, bonding with a female is beneficial for a male when either the spatial distribution of females or the temporal distribution of fertile periods makes it difficult for the males to defend access to more than one female at a time.
Species-specific analyses are recommended for additional species of the genera Hylobates, Nomascus (especially the black-cheeked taxa) and Hoolock.
Acknowledgments
We would like to thank the staff members of the numerous zoos for permission to study the gibbons in their care. We also would like to thank Kim J.J.M. Nouwen for her contribution in the data collection for our sample of pileated gibbons (Hylobates pileatus). We are grateful to Linda Burman-Hall for supporting this publication and for helpful comments on an earlier version of this manuscript.
Conflict of interest
There is no financial/personal interest, or contractual employment involving matters in this article or belief that could affect the authors’ objectivity.
\n',keywords:"social structure, pair bond, Symphalangus, Nomascus, Hylobates, sex-specific investment, Hylobatidae",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/74655.pdf",chapterXML:"https://mts.intechopen.com/source/xml/74655.xml",downloadPdfUrl:"/chapter/pdf-download/74655",previewPdfUrl:"/chapter/pdf-preview/74655",totalDownloads:400,totalViews:0,totalCrossrefCites:0,dateSubmitted:"September 24th 2020",dateReviewed:"November 27th 2020",datePrePublished:"December 30th 2020",datePublished:null,dateFinished:"December 30th 2020",readingETA:"0",abstract:"This study provides the first statistically significant evidence that the mechanisms of how pair bonds are created or maintained differ between gibbon taxa. We examine the pair bond in captive pairs of three genera of gibbons (Hylobatidae): siamangs (Symphalangus, N = 17 pairs), crested gibbons (Nomascus, N = 7 pairs), and pileated gibbons (Hylobates pileatus, N = 9 pairs). In the first part of this study, we determine three generally-accepted indicators of pair-bond strength (mutual grooming, behavioral synchronization and partner distance). A pairwise comparison of our samples reveals a difference in relative partner distances between siamangs and pileated gibbons, suggesting that siamangs may have a stronger pair bond than pileated gibbons. No difference among the three taxa was found in other variables believed to indicate pair bond strength. In the second part we examine the amount of partner-directed grooming in each sex. In siamangs, males invest significantly more into pair bonds than females, whereas the opposite is true in crested and pileated gibbons. Our results for siamangs correspond to predictions derived from the ‘mate-defense hypothesis’ for the evolution of pair bonds, whereas our results for crested gibbons and pileated gibbons correspond to predictions derived from the ‘male-services hypothesis’.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/74655",risUrl:"/chapter/ris/74655",signatures:"Thomas Geissmann, Simone Rosenkranz-Weck, Judith J.G.M. Van Der Loo and Mathias Orgeldinger",book:{id:"10665",type:"book",title:"Updates on Veterinary Anatomy and Physiology",subtitle:null,fullTitle:"Updates on Veterinary Anatomy and Physiology",slug:null,publishedDate:null,bookSignature:"Dr. Catrin Rutland and Prof. Samir El-Gendy",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",licenceType:"CC BY 3.0",editedByType:null,isbn:"978-1-83969-530-8",printIsbn:"978-1-83969-529-2",pdfIsbn:"978-1-83969-531-5",isAvailableForWebshopOrdering:!0,editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:null,sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Methods",level:"1"},{id:"sec_3",title:"3. Results",level:"1"},{id:"sec_3_2",title:"3.1 Strength of pair bonds",level:"2"},{id:"sec_3_3",title:"Table 1.",level:"3"},{id:"sec_4_3",title:"Table 2.",level:"3"},{id:"sec_5_3",title:"3.1.3 Allogrooming",level:"3"},{id:"sec_7_2",title:"3.2 Mechanism of pair bonds",level:"2"},{id:"sec_9",title:"4. Discussion",level:"1"},{id:"sec_9_2",title:"4.1 Pair bond strength",level:"2"},{id:"sec_10_2",title:"4.2 Pair bond maintenance",level:"2"},{id:"sec_12",title:"5. Conclusions",level:"1"},{id:"sec_13",title:"Acknowledgments",level:"1"},{id:"sec_16",title:"Conflict of interest",level:"1"}],chapterReferences:[{id:"B1",body:'Tuttle, RH. Apes of the World. Their Social Behavior, Communication, Mentality and Ecology. Park Ridge, NJ: Noyes Publications; 1986. xix+421 p.'},{id:"B2",body:'Fleagle JG. Primate Adaptation and Evolution. 3rd ed. San Diego and London: Academic Press; 2013. 441 p.'},{id:"B3",body:'Palombit RA. Infanticide and the evolution of pair bonds in nonhuman primates. 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Hannover: Institut für Zoologie, Tierärztliche Hochschule Hannover; 1998.'},{id:"B83",body:'Lukas KE, Barkauskas RT, Maher SA, Jacobs BA, Bauman JE, Henderson AJ, Calcagno JM. Longitudinal study of delayed reproductive success in a pair of white-cheeked gibbon (Hylobates leucogenys). Zoo Biology. 2002;21:413-434.'},{id:"B84",body:'Poyas AL. Pair bonding and parental care in socially monogamous primates: A comparative study of the white-cheeked gibbon (Nomascus leucogenys) and the white-faced saki (Pithecia pithecia) [Master’s thesis]. San Antonio: Department of Anthropology, University of Texas; 2008.'},{id:"B85",body:'Poyas AL, Bartlett TQ. Pair bonding in socially monogamous primates: A comparative study of the white-cheeked gibbon (Nomascus leucogenys) and the white-faced saki (Pithecia pithecia). American Journal of Physical Anthropology Supplement. 2009;48:214 (Abstract only).'},{id:"B86",body:'Embury AS. A study of the behaviour of captive gibbons [B.Sc. (Honour’s) thesis]. Parkville: Department of Zoology, University of Melbourne; 1983.'},{id:"B87",body:'Skyner L. The effect of visitors on the self-mutilation behaviour of a male pileated gibbon (Hylobates pileatus) at Blackpool Zoological Gardens [BSc (Honour’s) Animal Behaviour and Welfare thesis]. Myerscough: Myerscough College, in association with The University of Central Lancashire, UK; 2002.'},{id:"B88",body:'Riess BF. The behavior and social relations of the gibbon (Hylobates lar) observed under restricted free-range conditions. Zoologica. 1956;41:89-99.'},{id:"B89",body:'Steen, JC. Behavior of captive gibbons (Hylobates sp.): Study of a group of six animals in the Portland (Oreg.) Zoo [MSc (Master of Arts) thesis]. Portland: Department of Anthropology, University of Oregon; 1969.'},{id:"B90",body:'Ebert J. Paarungsverhalten weiblicher Weisshandgibbons (Hylobates lar) [Diploma thesis]. Berlin: Fachbereich Biologie, Chemie, Pharmazie, Freie Universität Berlin; 1999.'},{id:"B91",body:'Eichmüller P. Verhaltensbiologische Beobachtung der Silbergibbons (Hylobates moloch) des Tierparks Hellabrunn, München [Praktikumsarbeit zur Vorlesung Tierökologie und Verhalten, Sommersemester 2006, betreut durch Prof. Dr. Gerstmeier]. Munich: Lehrstuhl für Zoologie, Technische Universität München; 2006.'},{id:"B92",body:'Heufelder S. Eltern-Kind Beziehung und juveniles Spielverhalten von Hylobates moloch im Tierpark Hellabrunn, München [Praktikumsarbeit zur Vorlesung Verhaltensbiologie, betreut durch Prof. Dr. R. Gerstmeier]. Munich: Lehrstuhl für Zoologie, Technische Universität München; 2007.'},{id:"B93",body:'Schneider H. Verhaltensbiologische Beobachtung der Silbergibbons (Hylobates moloch) des Tierparks Hellabrunn, München [Praktikumsarbeit zur Vorlesung Verhaltensbiologie, betreut durch Prof. Dr. R. Gerstmeier]. Munich: Lehrstuhl für Zoologie, Technische Universität München; 2009.'},{id:"B94",body:'Sankaran S. Social behaviour and duetting in hoolock gibbons in Gibbon Wildlife Sanctuary, Assam [Master’s thesis]. Rajkot: Wildlife Science, Saurashtra University; 2009.'},{id:"B95",body:'Dunn PO, Whittingham LA, Pitcher TE. Mating systems, sperm competition, and the evolution of sexual dimorphism in birds. Evolution. 2001;55:161-175. DOI: 0.1111/j.0014-3820.2001.tb01281.x'},{id:"B96",body:'Lukas D, Clutton-Brock TH. The evolution of social monogamy in mammals. Science. 2013;341:526-530. Doi: 10.1126/science.1238677'},{id:"B97",body:'Brockelman WY, Srikosamatara S. Maintenance and evolution of social structure in gibbons. In: Preuschoft H, Chivers DJ, Brockelman WY, Creel N, editors. The Lesser Apes: Evolutionary and Behavioural Biology. Edinburgh: Edinburgh University Press; 1984. p. 298-323.'},{id:"B98",body:'Brockelman WY, Reichard U, Treesucon U, Raemaekers JJ. Dispersal, pair formation and social structure in gibbons (Hylobates lar). Behavioural Ecology and Sociobiology. 1998;42:329-339. DOI: 10.1007/s002650050445'},{id:"B99",body:'van Schaik CP. Social evolution in primates: The role of ecological factors and male behaviour. Proceedings of the British Academy. 1996;88:9-31.'},{id:"B100",body:'Cowlishaw G. Song function in gibbons. Behaviour. 1992;121:131-153. DOI: 10.1163/156853992X00471'},{id:"B101",body:'Geissmann T, Bohlen-Eyring S, Heuck A. The male song of the Javan silvery gibbon (Hylobates moloch). Contributions to Zoology. 2005;74:1-25. DOI: 10.1163/18759866-0740102001'},{id:"B102",body:'Roos C, Geissmann T. Molecular phylogeny of the major hylobatid divisions. Molecular Phylogenetics and Evolution. 2001;19:486-494. DOI: 10.1006/mpev.2001.0939'},{id:"B103",body:'Ellefson JO. A natural history of white-handed gibbons in the Malayan Peninsula. In: Rumbaugh DM, editor. Gibbon and Siamang, Vol. 3. Basel and New York: Karger; 1974. p. 1-136.'},{id:"B104",body:'Yi Y. Intra-group and inter-group social interactions in a pair-living primate, the Javan gibbon (Hylobates moloch) [Ph.D. thesis]. Seoul: Ewha Womans University; 2020.'},{id:"B105",body:'Ahsan MF. Socio-ecology of the hoolock gibbon (Hylobates hoolock) in two forests of Bangladesh. In: Chicago Zoological Society, editor. The Apes: Challenges for the 21st Century. Conference Proceedings; 10-13 May 2000; Brookfield Zoo. Brookfield, Illinois: Chicago Zoological Society; 2001. p. 286-299.'},{id:"B106",body:'Whitten AJ. The Kloss gibbon in Siberut rain forest [Ph.D. thesis]. Cambridge: Sub-Department of Veterinary Anatomy, University of Cambridge; 1980.'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Thomas Geissmann",address:"thomas.geissmann@aim.uzh.ch",affiliation:'
Department of Anthropology, Zurich University, Switzerland
'}],corrections:null},book:{id:"10665",type:"book",title:"Updates on Veterinary Anatomy and Physiology",subtitle:null,fullTitle:"Updates on Veterinary Anatomy and Physiology",slug:null,publishedDate:null,bookSignature:"Dr. Catrin Rutland and Prof. Samir El-Gendy",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",licenceType:"CC BY 3.0",editedByType:null,isbn:"978-1-83969-530-8",printIsbn:"978-1-83969-529-2",pdfIsbn:"978-1-83969-531-5",isAvailableForWebshopOrdering:!0,editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},profile:{item:{id:"181774",title:"Prof.",name:"Sarat Chandra",middleName:null,surname:"Yenisetti",email:"sarat@nagalanduniversity.ac.in",fullName:"Sarat Chandra Yenisetti",slug:"sarat-chandra-yenisetti",position:null,biography:"Dr. Sarat Chandra Yenisetti is an Associate Professor and Head of Drosophila Neurobiology Laboratory in Department of Zoology, Nagaland University (Central), Nagaland, India. He completed M.Sc. from Bangaluru University, India and was awarded a Ph.D. from Kuvempu University, India. Dr. Sarat obtained post-doctoral training in 'modelling Parkinson’s disease using Drosophila” from Neurogenetics, National Institute of Neurological Disorders and Stroke (NINDS) of National Institutes of Health (NIH), Bethesda, USA and University of Regensburg, Germany. His laboratory, funded through multiple research grants from Department of Biotechnology (DBT), India, University of Grants Commission (UGC), India and Department of Science and Technology (DST), India, focuses on Drosophila approach to understand Parkinson's Disease associated neurodegeneration as well as identification of novel therapeutic targets which may help to reduce the burden of PD in human.",institutionString:"Nagaland University",profilePictureURL:"https://mts.intechopen.com/storage/users/181774/images/system/181774.jpeg",totalCites:0,totalChapterViews:"0",outsideEditionCount:0,totalAuthoredChapters:"3",totalEditedBooks:"2",personalWebsiteURL:null,twitterURL:null,linkedinURL:null,institution:{name:"Nagaland University",institutionURL:null,country:{name:"India"}}},booksEdited:[{id:"7256",type:"book",slug:"dopamine-health-and-disease",title:"Dopamine",subtitle:"Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/7256.jpg",abstract:'The chemical basis of human emotions has been an exciting aspect in biology. The "feel-good chemical" dopamine (DA) is a hormone and also a neurotransmitter, which performs a critical role in reward and movement control in the brain. DA also performs multiple other functions outside the brain. Regulating unrelated critical biological functions makes this chemical a vital factor for sustaining life in both health and disease. Dopamine - Health and Disease is an endeavour with an objective to understand and appreciate the biological functions of DA in human wellbeing and its potential utility in biomedical research. This effort will supplement scientific and non-scientific communities in stimulating a critical understanding of the biological purpose of "ticklish" DA, which eventually supports the human relentless effort to reduce the burden of disease. As the most exciting molecule,dopamine directly impacts day-to-day life. Anyone who has an eye for health and disease-related concepts will find this book a good read.',editors:[{id:"181774",title:"Prof.",name:"Sarat Chandra",surname:"Yenisetti",slug:"sarat-chandra-yenisetti",fullName:"Sarat Chandra Yenisetti"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",title:"Edited Volume"}},{id:"6406",type:"book",slug:"parkinson-s-disease-understanding-pathophysiology-and-developing-therapeutic-strategies",title:"Parkinson's Disease",subtitle:"Understanding Pathophysiology and Developing Therapeutic Strategies",coverURL:"https://cdn.intechopen.com/books/images_new/6406.jpg",abstract:'Parkinson\'s disease (PD) is the second most common neurodegenerative disorder results due to loss of dopamine producing brain cells. Knowledge relating to PD condition has been known since 5000BC, however no effective therapeutic strategies are available till today. Therefore it is important for neurobiologists to work further by taking advantage of modern scientific methods and develop appropriate therapeutic strategies. Efforts in this direction are worthy as they will reduce the burden of PD among elderly, who are already burdened with age related systemic degenerative processes. This book is a humble effort in that progressive direction. It has chapters covering multiple aspects relating to etiology, pathophysiology of PD, available and futuristic therapeutics strategies. Therefore it will be of interest to common man, biomedical researchers and clinicians. This is one small step in a direction "to reduce the burden of neurological disease."',editors:[{id:"181774",title:"Prof.",name:"Sarat Chandra",surname:"Yenisetti",slug:"sarat-chandra-yenisetti",fullName:"Sarat Chandra Yenisetti"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",title:"Edited Volume"}}],chaptersAuthored:[{id:"50961",title:"Understanding Pathophysiology of Sporadic Parkinson's Disease in Drosophila Model: Potential Opportunities and Notable Limitations",slug:"understanding-pathophysiology-of-sporadic-parkinson-s-disease-in-drosophila-model-potential-opportun",abstract:"Parkinson’s disease (PD) is the second most common neurodegenerative disorder affecting approximately 1% of the population over age 50. PD is widely accepted as a multifactorial disease with both genetic and environmental contributions. Despite extensive research conducted in the area the precise etiological factors responsible remain elusive. In about 95% Parkinsonism is considered to have a sporadic component. There are currently no established curative, preventative, or disease-modifying interventions, stemming from a poor understanding of the molecular mechanisms of pathogenesis. Here lies the importance of animal models. Pharmacological insults cause Parkinsonian like phenotypes in Drosophila, thereby modelling sporadic PD. The pesticides paraquat and rotenone induced oxidative damage causing cluster specific DA neuron loss together with motor deficits. Studies in fly PD model have deciphered that signaling pathways such as phosphatidylinositol 3-kinase (PI3K/Akt and target of rapamycin (TOR), c-Jun N-terminal kinase (JNK) have been defective. Further, these studies have demonstrated that fruit fly can be a potential model to screen chemical compounds for their neuroprotective efficacy.",signatures:"Priyanka Modi, Ayajuddin Mohamad, Limamanen Phom, Zevelou\nKoza, Abhik Das, Rahul Chaurasia, Saikat Samadder, Bovito Achumi, Muralidhara, Rajesh Singh Pukhrambam and Sarat Chandra\nYenisetti",authors:[{id:"181774",title:"Prof.",name:"Sarat Chandra",surname:"Yenisetti",fullName:"Sarat Chandra Yenisetti",slug:"sarat-chandra-yenisetti",email:"sarat@nagalanduniversity.ac.in"},{id:"192493",title:"Dr.",name:"Priyanka",surname:"Modi",fullName:"Priyanka Modi",slug:"priyanka-modi",email:"pmodi82@gmail.com"},{id:"192494",title:"Mr.",name:"Ayajuddin",surname:"Mohamad",fullName:"Ayajuddin Mohamad",slug:"ayajuddin-mohamad",email:"md.ayaj@gmail.com"},{id:"192496",title:"Dr.",name:"Limamanen",surname:"Phom",fullName:"Limamanen Phom",slug:"limamanen-phom",email:"lim_angh@yahoo.co.in"},{id:"192499",title:"Dr.",name:"Zevelou",surname:"Koza",fullName:"Zevelou Koza",slug:"zevelou-koza",email:"zevi7koza@gmail.com"},{id:"192500",title:"Dr.",name:"Abhik",surname:"Das",fullName:"Abhik Das",slug:"abhik-das",email:"dasabhik91@gmail.com"},{id:"192501",title:"Dr.",name:"Rahul",surname:"Chaurasia",fullName:"Rahul Chaurasia",slug:"rahul-chaurasia",email:"rahulneuro12@gmail.com"},{id:"192502",title:"Dr.",name:"Saikat",surname:"Samadder",fullName:"Saikat Samadder",slug:"saikat-samadder",email:"saikat.samadder46@gmail.com"},{id:"192503",title:"Dr.",name:"Bovito",surname:"Achumi",fullName:"Bovito Achumi",slug:"bovito-achumi",email:"bovitoachumi@ymail.com"},{id:"192508",title:"Dr.",name:"Rajesh Singh",surname:"Pukhrambam",fullName:"Rajesh Singh Pukhrambam",slug:"rajesh-singh-pukhrambam",email:"rrsing.singh@gmail.com"},{id:"192509",title:"Dr.",name:null,surname:"Muralidhara",fullName:"Muralidhara",slug:"muralidhara",email:"mura16@yahoo.com"}],book:{id:"5277",title:"Challenges in Parkinson's Disease",slug:"challenges-in-parkinson-s-disease",productType:{id:"1",title:"Edited Volume"}}},{id:"57879",title:"Parkinson’s Disease: Insights from Drosophila Model",slug:"parkinson-s-disease-insights-from-drosophila-model",abstract:"Parkinson’s disease (PD) is a medical condition that has been known since ancient times. It is the second most common neurodegenerative disorder affecting approximately 1% of the population over 50 years. It is characterized by both motor and non-motor symptoms. Most of PD cases are sporadic while 5–10% cases are familial. Environment factors such as exposure to pesticides, herbicides and other heavy metals are expected to be the main cause of sporadic form of the disease. Mutation of the susceptible genes such as SNCA, PINK1, PARKIN, DJ1, and others are considered to be the main cause of the familial form of disease. Drosophila offers many advantages for studying human neurodegenerative diseases and their underlying molecular and cellular pathology. Shorter life span; large number of progeny; conserved molecular mechanism(s) among fly, mice and human; availability of many techniques, and tools to manipulate gene expression makes drosophila a potential model system to understand the pathology associated with PD and to unravel underlying molecular mechanism(s) responsible for dopaminergic neurodegeneration in PD—understanding of which will be of potential assistance to develop therapeutic strategies to PD. In the present review, we made an effort to discuss the contribution of fly model to understand pathophysiology of PD, in understanding the biological functions of genes implicated in PD; to understand the gene-environment interaction in PD; and validation of clues that are generated through genome-wide association studies (GWAS) in human through fly; further to screen and develop potential therapeutic molecules for PD. In nutshell, fly has been a great model system which has immensely contributed to the biomedical research relating to understand and addressing the pathology of human neurological diseases in general and PD in particular.",signatures:"Mohamad Ayajuddin, Abhik Das, Limamanen Phom, Priyanka Modi,\nRahul Chaurasia, Zevelou Koza, Abuno Thepa, Nukshimenla Jamir,\nPukhrambam Rajesh Singh, Sentinungla Longkumer, Pardeshi Lal\nand Sarat Chandra Yenisetti",authors:[{id:"181774",title:"Prof.",name:"Sarat Chandra",surname:"Yenisetti",fullName:"Sarat Chandra Yenisetti",slug:"sarat-chandra-yenisetti",email:"sarat@nagalanduniversity.ac.in"}],book:{id:"5976",title:"Drosophila melanogaster",slug:"drosophila-melanogaster-model-for-recent-advances-in-genetics-and-therapeutics",productType:{id:"1",title:"Edited Volume"}}},{id:"63820",title:"Introductory Chapter: “Feel Good” Chemical Dopamine - Role in Health and Disease",slug:"introductory-chapter-feel-good-chemical-dopamine-role-in-health-and-disease",abstract:null,signatures:"Sarat Chandra Yenisetti",authors:[{id:"181774",title:"Prof.",name:"Sarat Chandra",surname:"Yenisetti",fullName:"Sarat Chandra Yenisetti",slug:"sarat-chandra-yenisetti",email:"sarat@nagalanduniversity.ac.in"}],book:{id:"7256",title:"Dopamine",slug:"dopamine-health-and-disease",productType:{id:"1",title:"Edited Volume"}}}],collaborators:[{id:"181681",title:"Dr.",name:"Massimo",surname:"Piacentino",slug:"massimo-piacentino",fullName:"Massimo Piacentino",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"182192",title:"Dr.",name:"Maria",surname:"Satue",slug:"maria-satue",fullName:"Maria Satue",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Barcelona",institutionURL:null,country:{name:"Spain"}}},{id:"182717",title:"Dr.",name:"Vicente",surname:"Polo",slug:"vicente-polo",fullName:"Vicente Polo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"183172",title:"Mr.",name:"Unax",surname:"Lertxundi",slug:"unax-lertxundi",fullName:"Unax Lertxundi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"185354",title:"Dr.",name:"Rafael",surname:"Hernández",slug:"rafael-hernandez",fullName:"Rafael Hernández",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"185355",title:"Mrs.",name:"Saioa",surname:"Domingo-Echaburu",slug:"saioa-domingo-echaburu",fullName:"Saioa Domingo-Echaburu",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"185356",title:"Mr.",name:"Javier",surname:"Peral-Aguirregoitia",slug:"javier-peral-aguirregoitia",fullName:"Javier Peral-Aguirregoitia",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"185357",title:"Dr.",name:"Juan",surname:"Medrano",slug:"juan-medrano",fullName:"Juan Medrano",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"186117",title:"Dr.",name:"Giacomo",surname:"Beggio",slug:"giacomo-beggio",fullName:"Giacomo Beggio",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"186118",title:"Dr.",name:"Lorenzo",surname:"Volpin",slug:"lorenzo-volpin",fullName:"Lorenzo Volpin",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null}]},generic:{page:{slug:"OA-publishing-fees",title:"Open Access Publishing Fees",intro:"
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As a gold Open Access publisher, an Open Access Publishing Fee is payable on acceptance following peer review of the manuscript. In return, we provide high quality publishing services and exclusive benefits for all contributors. IntechOpen is the trusted publishing partner of over 140,000 international scientists and researchers.
\n\n
The Open Access Publishing Fee (OAPF) is payable only after your book chapter, monograph or journal article is accepted for publication.
\n\n
OAPF Publishing Options
\n\n
\n\t
1,400 GBP Chapter - Edited Volume
\n\t
850 GBP Chapter - Book Series Topic (Annual Volume)
\n\t
10,000 GBP Monograph - Long Form
\n\t
4,000 GBP Compacts Monograph - Short Form
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850 GBP Journal Article (Across Portfolio)
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During the launching phase journals do not charge an APC, rather they will be funded by IntechOpen.
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*These prices do not include Value-Added Tax (VAT). Residents of European Union countries need to add VAT based on the specific rate in their country of residence. Institutions and companies registered as VAT taxable entities in their own EU member state will not pay VAT as long as provision of the VAT registration number is made during the application process. This is made possible by the EU reverse charge method.
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It is possible to evaluate the silica network formation along the hydrolysis and condensation reactions in terms of siloxane rings formation and Si–O(–Si) angle deformation due to the introduction of organic groups, the employed synthetic route or encapsulated species interaction. The siloxane four- or six-membered rings imply in a more rigid or flexible network, respectively, in order to accommodate the organic groups. A structural analysis of the materials is of high importance, since interactions between the encapsulated molecules and the matrix are critical for the device performance, such as sensors. This type of device needs the permeation of an analyte to activate the encapsulated receptor molecules inside the silica structure. Fourier transform infrared spectrometry can be also used to determine parameters of the silica network as a function of the hydrophilicity/hydrophobicity degree and the siloxane ring structure with respect to thin film porosity. This silica structural analysis is reviewed along the text in a tentative of better exploring the data resulting from these powerful techniques. In addition, the functionalization of silica structures by the use of organoalkoxysilanes, which is important to the creation of high-specific materials, can be well described by these two complementary techniques. The Si–C bonds and the maintenance of the organic substituents such as methyl, octyl, octadecyl, vinyl, phenyl, aminopropyl, mercaptopropyl, isocyanatopropyl, iodopropyl, chloropropyl and glicydoxypropyl could be evaluated after the sol-gel synthesis process. The literature regarding silica vibrational spectroscopy is also explored creating a data bank of wave numbers for the most important bonds for different types of silica and hybrid silica materials obtained by different synthetic routes.",book:{id:"5283",slug:"applications-of-molecular-spectroscopy-to-current-research-in-the-chemical-and-biological-sciences",title:"Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences",fullTitle:"Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences"},signatures:"Larissa Brentano Capeletti and João Henrique Zimnoch",authors:[{id:"178200",title:"Prof.",name:"Joao Henrique",middleName:null,surname:"Zimnoch Dos Santos",slug:"joao-henrique-zimnoch-dos-santos",fullName:"Joao Henrique Zimnoch Dos Santos"},{id:"186947",title:"Dr.",name:"Larissa",middleName:null,surname:"Brentano Capeletti",slug:"larissa-brentano-capeletti",fullName:"Larissa Brentano Capeletti"}]},{id:"63324",doi:"10.5772/intechopen.80430",title:"Fatty Acids: From Membrane Ingredients to Signaling Molecules",slug:"fatty-acids-from-membrane-ingredients-to-signaling-molecules",totalDownloads:1634,totalCrossrefCites:11,totalDimensionsCites:21,abstract:"Fatty acid constitutes the foundation cell membranes, provides metabolic energy, affects functions of membrane-bound enzymes/receptors, conducts signaling cascades, and helps in learning-related memory cognition in mammals, including humans. Structurally, the fatty acids are of two kinds: saturated and unsaturated; the latter are again of mono- and polyunsaturated types. From nutritional perspectives, they are of essential and nonessential types. Omega-6 linoleic acid (ω-6 LLA, C18:2) and ω-3 alpha linolenic acid (ω-3 αLLN, C18:3) and ω-6 arachidonic acid [(ω-6 AA, C20:4); it is conditional] are essential fatty acids (EFAs). In addition, mammalian brains cannot biosynthesize the ω-3 docosahexaenoic acid (ω-3 DHA, C22:6) in adequate amounts because of lack of necessary enzymes. Thus, DHA is essential for the growth and development of the brains. Deficiency of DHA produces visual- and learning-related memory impairments, and neurodegeneration in the aged brains and Alzheimer’s disease brains. Finally, this chapter will highlight and broaden the awareness about the essentiality of different fatty acids with a special emphasis on DHA.",book:{id:"7006",slug:"biochemistry-and-health-benefits-of-fatty-acids",title:"Biochemistry and Health Benefits of Fatty Acids",fullTitle:"Biochemistry and Health Benefits of Fatty Acids"},signatures:"Michio Hashimoto and Shahdat Hossain",authors:[{id:"260006",title:"Prof.",name:"Shahdat",middleName:null,surname:"Hossain",slug:"shahdat-hossain",fullName:"Shahdat Hossain"},{id:"260206",title:"Prof.",name:"Michio",middleName:null,surname:"Hashimoto",slug:"michio-hashimoto",fullName:"Michio Hashimoto"}]},{id:"43080",doi:"10.5772/55287",title:"Grain Yield Determination and Resource Use Efficiency in Maize Hybrids Released in Different Decades",slug:"grain-yield-determination-and-resource-use-efficiency-in-maize-hybrids-released-in-different-decades",totalDownloads:4875,totalCrossrefCites:4,totalDimensionsCites:15,abstract:null,book:{id:"3586",slug:"agricultural-chemistry",title:"Agricultural Chemistry",fullTitle:"Agricultural Chemistry"},signatures:"Laura Echarte, Lujan Nagore, Javier Di Matteo, Matías Cambareri, Mariana Robles and Aída Della Maggiora",authors:[{id:"164811",title:"Dr.",name:"Laura",middleName:null,surname:"Echarte",slug:"laura-echarte",fullName:"Laura Echarte"},{id:"165595",title:"Dr.",name:"Maria",middleName:"Lujan",surname:"Nagore",slug:"maria-nagore",fullName:"Maria Nagore"},{id:"165596",title:"BSc.",name:"Javier",middleName:null,surname:"Di Matteo",slug:"javier-di-matteo",fullName:"Javier Di Matteo"},{id:"165598",title:"BSc.",name:"Mariana",middleName:null,surname:"Robles",slug:"mariana-robles",fullName:"Mariana Robles"},{id:"165599",title:"MSc.",name:"Aída",middleName:null,surname:"Della Maggiora",slug:"aida-della-maggiora",fullName:"Aída Della Maggiora"},{id:"167765",title:"Dr.",name:"Matias",middleName:null,surname:"Cambareri",slug:"matias-cambareri",fullName:"Matias Cambareri"}]},{id:"51767",doi:"10.5772/64581",title:"Applications of Molecular Spectroscopic Methods to the Elucidation of Lignin Structure",slug:"applications-of-molecular-spectroscopic-methods-to-the-elucidation-of-lignin-structure",totalDownloads:2936,totalCrossrefCites:3,totalDimensionsCites:14,abstract:"Lignin in plant cell wall is a complex amorphous polymer and is biosynthesized mainly from three aromatic alcohols, namely, p-coumaryl, coniferyl, and sinapyl alcohols. This biosynthesis process consists of mainly radical coupling reactions and creates a unique lignin polymer in each plant species. Generally, lignin mainly consists of p-hydroxyphenyl (H), guaiacyl (G), and syringyl (S) units and is linked by several types of carbon-carbon (β-β, β-5, β-1, and 5–5) and ether bonds. Due to the structural complexity, various molecular spectroscopic methods have been applied to unravel the aromatic units and different interunit linkages in lignin from different plant species. This chapter is focused on the application of ultraviolet (UV) spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, Fourier transform Raman (FT-Raman) spectroscopy, fluorescence spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy to lignin structural elucidation.",book:{id:"5283",slug:"applications-of-molecular-spectroscopy-to-current-research-in-the-chemical-and-biological-sciences",title:"Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences",fullTitle:"Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences"},signatures:"Tingting You and Feng Xu",authors:[{id:"174103",title:"Prof.",name:"Feng",middleName:null,surname:"Xu",slug:"feng-xu",fullName:"Feng Xu"},{id:"182550",title:"Dr.",name:"Tingting",middleName:null,surname:"You",slug:"tingting-you",fullName:"Tingting You"}]},{id:"43053",doi:"10.5772/55416",title:"In vitro Antioxidant Analysis and the DNA Damage Protective Activity of Leaf Extract of the Excoecaria agallocha Linn Mangrove Plant",slug:"in-vitro-antioxidant-analysis-and-the-dna-damage-protective-activity-of-leaf-extract-of-the-excoecar",totalDownloads:3360,totalCrossrefCites:1,totalDimensionsCites:12,abstract:null,book:{id:"3586",slug:"agricultural-chemistry",title:"Agricultural Chemistry",fullTitle:"Agricultural Chemistry"},signatures:"C. Asha Poorna, M.S. Resmi and E.V. Soniya",authors:[{id:"148913",title:"Dr.",name:"Soniya",middleName:null,surname:"E V",slug:"soniya-e-v",fullName:"Soniya E V"}]}],mostDownloadedChaptersLast30Days:[{id:"51767",title:"Applications of Molecular Spectroscopic Methods to the Elucidation of Lignin Structure",slug:"applications-of-molecular-spectroscopic-methods-to-the-elucidation-of-lignin-structure",totalDownloads:2934,totalCrossrefCites:3,totalDimensionsCites:14,abstract:"Lignin in plant cell wall is a complex amorphous polymer and is biosynthesized mainly from three aromatic alcohols, namely, p-coumaryl, coniferyl, and sinapyl alcohols. This biosynthesis process consists of mainly radical coupling reactions and creates a unique lignin polymer in each plant species. Generally, lignin mainly consists of p-hydroxyphenyl (H), guaiacyl (G), and syringyl (S) units and is linked by several types of carbon-carbon (β-β, β-5, β-1, and 5–5) and ether bonds. Due to the structural complexity, various molecular spectroscopic methods have been applied to unravel the aromatic units and different interunit linkages in lignin from different plant species. This chapter is focused on the application of ultraviolet (UV) spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, Fourier transform Raman (FT-Raman) spectroscopy, fluorescence spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy to lignin structural elucidation.",book:{id:"5283",slug:"applications-of-molecular-spectroscopy-to-current-research-in-the-chemical-and-biological-sciences",title:"Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences",fullTitle:"Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences"},signatures:"Tingting You and Feng Xu",authors:[{id:"174103",title:"Prof.",name:"Feng",middleName:null,surname:"Xu",slug:"feng-xu",fullName:"Feng Xu"},{id:"182550",title:"Dr.",name:"Tingting",middleName:null,surname:"You",slug:"tingting-you",fullName:"Tingting You"}]},{id:"62041",title:"Assessment of Sugarcane-Based Ethanol Production",slug:"assessment-of-sugarcane-based-ethanol-production",totalDownloads:2249,totalCrossrefCites:3,totalDimensionsCites:12,abstract:"This chapter aims to explain how bio-ethanol has been drawn to become a successful alternative to partially replace petroleum as a source of liquid fuels in Brazil. A brief historical analysis about the production of bio-ethanol from sugarcane is presented. The motivation to start the production of the ethanol as biofuel in the 1970s and how the governmental policies have contributed to the ups and downs, successes, and failures of the sugarcane industry is shown. Then, the efficiency of the sector is addressed; firstly, the increasing efficiency of the agricultural sector is discussed, showing how the productivity per hectare has increased in the last decades and which improvements are further expected in a near future. Finally, the industrial process is discussed: the current efficiency in processing sugarcane to produce ethanol and the emerging technologies, not only to process sugarcane juice, but also to harness bagasse, vinasse, and sugarcane straw.",book:{id:"7238",slug:"fuel-ethanol-production-from-sugarcane",title:"Fuel Ethanol Production from Sugarcane",fullTitle:"Fuel Ethanol Production from Sugarcane"},signatures:"Rubens Eliseu Nicula de Castro, Rita Maria de Brito Alves,\nCláudio Augusto Oller do Nascimento and Reinaldo Giudici",authors:[{id:"50350",title:"Prof.",name:"Claudio",middleName:null,surname:"Oller Do Nascimento",slug:"claudio-oller-do-nascimento",fullName:"Claudio Oller Do Nascimento"},{id:"98033",title:"Dr.",name:"Rita Maria",middleName:null,surname:"De Brito Alves",slug:"rita-maria-de-brito-alves",fullName:"Rita Maria De Brito Alves"},{id:"248441",title:"BSc.",name:"Rubens E",middleName:null,surname:"N De Castro",slug:"rubens-e-n-de-castro",fullName:"Rubens E N De Castro"},{id:"248442",title:"Prof.",name:"Reinaldo",middleName:null,surname:"Giudici",slug:"reinaldo-giudici",fullName:"Reinaldo Giudici"}]},{id:"52212",title:"Fourier Transform Infrared and Raman Characterization of Silica-Based Materials",slug:"fourier-transform-infrared-and-raman-characterization-of-silica-based-materials",totalDownloads:3449,totalCrossrefCites:14,totalDimensionsCites:34,abstract:"Fourier Transform Infrared and Raman are powerful techniques to evaluate silica and hybrid silica structure. It is possible to evaluate the silica network formation along the hydrolysis and condensation reactions in terms of siloxane rings formation and Si–O(–Si) angle deformation due to the introduction of organic groups, the employed synthetic route or encapsulated species interaction. The siloxane four- or six-membered rings imply in a more rigid or flexible network, respectively, in order to accommodate the organic groups. A structural analysis of the materials is of high importance, since interactions between the encapsulated molecules and the matrix are critical for the device performance, such as sensors. This type of device needs the permeation of an analyte to activate the encapsulated receptor molecules inside the silica structure. Fourier transform infrared spectrometry can be also used to determine parameters of the silica network as a function of the hydrophilicity/hydrophobicity degree and the siloxane ring structure with respect to thin film porosity. This silica structural analysis is reviewed along the text in a tentative of better exploring the data resulting from these powerful techniques. In addition, the functionalization of silica structures by the use of organoalkoxysilanes, which is important to the creation of high-specific materials, can be well described by these two complementary techniques. The Si–C bonds and the maintenance of the organic substituents such as methyl, octyl, octadecyl, vinyl, phenyl, aminopropyl, mercaptopropyl, isocyanatopropyl, iodopropyl, chloropropyl and glicydoxypropyl could be evaluated after the sol-gel synthesis process. The literature regarding silica vibrational spectroscopy is also explored creating a data bank of wave numbers for the most important bonds for different types of silica and hybrid silica materials obtained by different synthetic routes.",book:{id:"5283",slug:"applications-of-molecular-spectroscopy-to-current-research-in-the-chemical-and-biological-sciences",title:"Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences",fullTitle:"Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences"},signatures:"Larissa Brentano Capeletti and João Henrique Zimnoch",authors:[{id:"178200",title:"Prof.",name:"Joao Henrique",middleName:null,surname:"Zimnoch Dos Santos",slug:"joao-henrique-zimnoch-dos-santos",fullName:"Joao Henrique Zimnoch Dos Santos"},{id:"186947",title:"Dr.",name:"Larissa",middleName:null,surname:"Brentano Capeletti",slug:"larissa-brentano-capeletti",fullName:"Larissa Brentano Capeletti"}]},{id:"63324",title:"Fatty Acids: From Membrane Ingredients to Signaling Molecules",slug:"fatty-acids-from-membrane-ingredients-to-signaling-molecules",totalDownloads:1630,totalCrossrefCites:10,totalDimensionsCites:20,abstract:"Fatty acid constitutes the foundation cell membranes, provides metabolic energy, affects functions of membrane-bound enzymes/receptors, conducts signaling cascades, and helps in learning-related memory cognition in mammals, including humans. Structurally, the fatty acids are of two kinds: saturated and unsaturated; the latter are again of mono- and polyunsaturated types. From nutritional perspectives, they are of essential and nonessential types. Omega-6 linoleic acid (ω-6 LLA, C18:2) and ω-3 alpha linolenic acid (ω-3 αLLN, C18:3) and ω-6 arachidonic acid [(ω-6 AA, C20:4); it is conditional] are essential fatty acids (EFAs). In addition, mammalian brains cannot biosynthesize the ω-3 docosahexaenoic acid (ω-3 DHA, C22:6) in adequate amounts because of lack of necessary enzymes. Thus, DHA is essential for the growth and development of the brains. Deficiency of DHA produces visual- and learning-related memory impairments, and neurodegeneration in the aged brains and Alzheimer’s disease brains. Finally, this chapter will highlight and broaden the awareness about the essentiality of different fatty acids with a special emphasis on DHA.",book:{id:"7006",slug:"biochemistry-and-health-benefits-of-fatty-acids",title:"Biochemistry and Health Benefits of Fatty Acids",fullTitle:"Biochemistry and Health Benefits of Fatty Acids"},signatures:"Michio Hashimoto and Shahdat Hossain",authors:[{id:"260006",title:"Prof.",name:"Shahdat",middleName:null,surname:"Hossain",slug:"shahdat-hossain",fullName:"Shahdat Hossain"},{id:"260206",title:"Prof.",name:"Michio",middleName:null,surname:"Hashimoto",slug:"michio-hashimoto",fullName:"Michio Hashimoto"}]},{id:"63553",title:"Cyclic Fatty Acids in Food: An Under-Investigated Class of Fatty Acids",slug:"cyclic-fatty-acids-in-food-an-under-investigated-class-of-fatty-acids",totalDownloads:1340,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"Cyclic fatty acids are an unusual class of minor fatty acids generally produced by bacteria and less frequently by plants. Among plants, the most known cyclic fatty acid is sterculic acid (9, 10-methyleneoctadecenoic acid) produced by Sterculia foetida. Bacteria (e.g., lactic acid bacteria) synthetize cyclopropane fatty acids, such as dihydrosterculic acid (9, 10-methylene octadecanoic acid) and lactobacillic acid (11, 12 methylene octadecanoic acid), to strength their membrane, improving their resistance to environmental stress. Another class of cyclic fatty acids is omega-cyclohexyl fatty acids, present in milk and probably produced by rumen bacteria. Cyclopropane and omega-cyclohexyl fatty acids have been recently found in bovine meat and dairy products, representing important foodstuffs in human diet. In this chapter, a review of literature data concerning the presence of cyclic fatty acids in foods, their metabolism in humans, and their potential bioactivity will be provided. The role of some cyclic fatty acids as molecular markers for food authenticity will also be highlighted.",book:{id:"7006",slug:"biochemistry-and-health-benefits-of-fatty-acids",title:"Biochemistry and Health Benefits of Fatty Acids",fullTitle:"Biochemistry and Health Benefits of Fatty Acids"},signatures:"Augusta Caligiani and Veronica Lolli",authors:[{id:"257412",title:"Ph.D.",name:"Augusta",middleName:null,surname:"Caligiani",slug:"augusta-caligiani",fullName:"Augusta Caligiani"},{id:"257577",title:"Dr.",name:"Veronica",middleName:null,surname:"Lolli",slug:"veronica-lolli",fullName:"Veronica Lolli"}]}],onlineFirstChaptersFilter:{topicId:"82",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:320,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:133,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:16,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403",scope:"Artificial Intelligence (AI) is a rapidly developing multidisciplinary research area that aims to solve increasingly complex problems. In today's highly integrated world, AI promises to become a robust and powerful means for obtaining solutions to previously unsolvable problems. This Series is intended for researchers and students alike interested in this fascinating field and its many applications.",coverUrl:"https://cdn.intechopen.com/series/covers/14.jpg",latestPublicationDate:"July 5th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:9,editor:{id:"218714",title:"Prof.",name:"Andries",middleName:null,surname:"Engelbrecht",slug:"andries-engelbrecht",fullName:"Andries Engelbrecht",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRNR8QAO/Profile_Picture_1622640468300",biography:"Andries Engelbrecht received the Masters and PhD degrees in Computer Science from the University of Stellenbosch, South Africa, in 1994 and 1999 respectively. He is currently appointed as the Voigt Chair in Data Science in the Department of Industrial Engineering, with a joint appointment as Professor in the Computer Science Division, Stellenbosch University. Prior to his appointment at Stellenbosch University, he has been at the University of Pretoria, Department of Computer Science (1998-2018), where he was appointed as South Africa Research Chair in Artifical Intelligence (2007-2018), the head of the Department of Computer Science (2008-2017), and Director of the Institute for Big Data and Data Science (2017-2018). In addition to a number of research articles, he has written two books, Computational Intelligence: An Introduction and Fundamentals of Computational Swarm Intelligence.",institutionString:null,institution:{name:"Stellenbosch University",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:6,paginationItems:[{id:"22",title:"Applied Intelligence",coverUrl:"https://cdn.intechopen.com/series_topics/covers/22.jpg",isOpenForSubmission:!0,annualVolume:11418,editor:{id:"27170",title:"Prof.",name:"Carlos",middleName:"M.",surname:"Travieso-Gonzalez",slug:"carlos-travieso-gonzalez",fullName:"Carlos Travieso-Gonzalez",profilePictureURL:"https://mts.intechopen.com/storage/users/27170/images/system/27170.jpeg",biography:"Carlos M. Travieso-González received his MSc degree in Telecommunication Engineering at Polytechnic University of Catalonia (UPC), Spain in 1997, and his Ph.D. degree in 2002 at the University of Las Palmas de Gran Canaria (ULPGC-Spain). He is a full professor of signal processing and pattern recognition and is head of the Signals and Communications Department at ULPGC, teaching from 2001 on subjects on signal processing and learning theory. His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. He is the founder of The IEEE IWOBI conference series and the president of its Steering Committee, as well as the founder of both the InnoEducaTIC and APPIS conference series. He is an evaluator of project proposals for the European Union (H2020), Medical Research Council (MRC, UK), Spanish Government (ANECA, Spain), Research National Agency (ANR, France), DAAD (Germany), Argentinian Government, and the Colombian Institutions. He has been a reviewer in different indexed international journals (<70) and conferences (<250) since 2001. He has been a member of the IASTED Technical Committee on Image Processing from 2007 and a member of the IASTED Technical Committee on Artificial Intelligence and Expert Systems from 2011. \n\nHe has held the general chair position for the following: ACM-APPIS (2020, 2021), IEEE-IWOBI (2019, 2020 and 2020), A PPIS (2018, 2019), IEEE-IWOBI (2014, 2015, 2017, 2018), InnoEducaTIC (2014, 2017), IEEE-INES (2013), NoLISP (2011), JRBP (2012), and IEEE-ICCST (2005)\n\nHe is an associate editor of the Computational Intelligence and Neuroscience Journal (Hindawi – Q2 JCR-ISI). He was vice dean from 2004 to 2010 in the Higher Technical School of Telecommunication Engineers at ULPGC and the vice dean of Graduate and Postgraduate Studies from March 2013 to November 2017. He won the “Catedra Telefonica” Awards in Modality of Knowledge Transfer, 2017, 2018, and 2019 editions, and awards in Modality of COVID Research in 2020.\n\nPublic References:\nResearcher ID http://www.researcherid.com/rid/N-5967-2014\nORCID https://orcid.org/0000-0002-4621-2768 \nScopus Author ID https://www.scopus.com/authid/detail.uri?authorId=6602376272\nScholar Google https://scholar.google.es/citations?user=G1ks9nIAAAAJ&hl=en \nResearchGate https://www.researchgate.net/profile/Carlos_Travieso",institutionString:null,institution:{name:"University of Las Palmas de Gran Canaria",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"23",title:"Computational Neuroscience",coverUrl:"https://cdn.intechopen.com/series_topics/covers/23.jpg",isOpenForSubmission:!0,annualVolume:11419,editor:{id:"14004",title:"Dr.",name:"Magnus",middleName:null,surname:"Johnsson",slug:"magnus-johnsson",fullName:"Magnus Johnsson",profilePictureURL:"https://mts.intechopen.com/storage/users/14004/images/system/14004.png",biography:"Dr Magnus Johnsson is a cross-disciplinary scientist, lecturer, scientific editor and AI/machine learning consultant from Sweden. \n\nHe is currently at Malmö University in Sweden, but also held positions at Lund University in Sweden and at Moscow Engineering Physics Institute. \nHe holds editorial positions at several international scientific journals and has served as a scientific editor for books and special journal issues. \nHis research interests are wide and include, but are not limited to, autonomous systems, computer modeling, artificial neural networks, artificial intelligence, cognitive neuroscience, cognitive robotics, cognitive architectures, cognitive aids and the philosophy of mind. \n\nDr. Johnsson has experience from working in the industry and he has a keen interest in the application of neural networks and artificial intelligence to fields like industry, finance, and medicine. \n\nWeb page: www.magnusjohnsson.se",institutionString:null,institution:{name:"Malmö University",institutionURL:null,country:{name:"Sweden"}}},editorTwo:null,editorThree:null},{id:"24",title:"Computer Vision",coverUrl:"https://cdn.intechopen.com/series_topics/covers/24.jpg",isOpenForSubmission:!0,annualVolume:11420,editor:{id:"294154",title:"Prof.",name:"George",middleName:null,surname:"Papakostas",slug:"george-papakostas",fullName:"George Papakostas",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002hYaGbQAK/Profile_Picture_1624519712088",biography:"George A. 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He has (co)authored more than 150 publications in indexed journals, international conferences and book chapters, 1 book (in Greek), 3 edited books, and 5 journal special issues. His publications have more than 2100 citations with h-index 27 (GoogleScholar). His research interests include computer/machine vision, machine learning, pattern recognition, computational intelligence. \nDr. Papakostas served as a reviewer in numerous journals, as a program\ncommittee member in international conferences and he is a member of the IAENG, MIR Labs, EUCogIII, INSTICC and the Technical Chamber of Greece (TEE).",institutionString:null,institution:{name:"International Hellenic University",institutionURL:null,country:{name:"Greece"}}},editorTwo:null,editorThree:null},{id:"25",title:"Evolutionary Computation",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",isOpenForSubmission:!0,annualVolume:11421,editor:{id:"136112",title:"Dr.",name:"Sebastian",middleName:null,surname:"Ventura Soto",slug:"sebastian-ventura-soto",fullName:"Sebastian Ventura Soto",profilePictureURL:"https://mts.intechopen.com/storage/users/136112/images/system/136112.png",biography:"Sebastian Ventura is a Spanish researcher, a full professor with the Department of Computer Science and Numerical Analysis, University of Córdoba. 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In the last five years, he has published more than 60 papers in international journals indexed in the JCR (around 70% of them belonging to first quartile journals) and he has edited some Springer books “Supervised Descriptive Pattern Mining” (2018), “Multiple Instance Learning - Foundations and Algorithms” (2016), and “Pattern Mining with Evolutionary Algorithms” (2016). He has also been involved in more than 20 research projects supported by the Spanish and Andalusian governments and the European Union. He currently belongs to the editorial board of PeerJ Computer Science, Information Fusion and Engineering Applications of Artificial Intelligence journals, being also associate editor of Applied Computational Intelligence and Soft Computing and IEEE Transactions on Cybernetics. Finally, he is editor-in-chief of Progress in Artificial Intelligence. 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He obtained both his M.Sc. and Ph.D. from the University of Liverpool, England, in the field of Intelligent Systems. He is a full professor at the Universidad Autonoma de Queretaro, Mexico, and a member of the National System of Researchers (SNI) since 2009. Dr. Aceves Fernandez has published more than 80 research papers as well as a number of book chapters and congress papers. He has contributed in more than 20 funded research projects, both academic and industrial, in the area of artificial intelligence, ranging from environmental, biomedical, automotive, aviation, consumer, and robotics to other applications. He is also a honorary president at the National Association of Embedded Systems (AMESE), a senior member of the IEEE, and a board member of many institutions. 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Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Bacterial Infectious Diseases",value:3,count:2},{group:"subseries",caption:"Parasitic Infectious Diseases",value:5,count:4},{group:"subseries",caption:"Viral Infectious Diseases",value:6,count:7}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:2},{group:"publicationYear",caption:"2021",value:2021,count:4},{group:"publicationYear",caption:"2020",value:2020,count:3},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:250,paginationItems:[{id:"274452",title:"Dr.",name:"Yousif",middleName:"Mohamed",surname:"Abdallah",slug:"yousif-abdallah",fullName:"Yousif Abdallah",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274452/images/8324_n.jpg",biography:"I certainly enjoyed my experience in Radiotherapy and Nuclear Medicine, particularly it has been in different institutions and hospitals with different Medical Cultures and allocated resources. Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:null},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. RELACION DE PONENCIAS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGIA. 10/2014.",institutionString:null,institution:null},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:null},{id:"243698",title:"Dr.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. 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Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"July 5th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:4,numberOfPublishedChapters:320,numberOfPublishedBooks:32,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"14",title:"Cell and Molecular Biology",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. 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