\r\n\tThus, we call for research and review papers on the chemistry and physics of dyes, pigments, and their intermediates, including chemical constituents, spectroscopic aspects, surface, solution, crystal formation, photochemical, and ecological or biological properties. The book will be of interest to a wide variety of researchers worldwide whose work involves various fields of activity such as dyes and pigment synthesis, imaging, sensor, energy, medicine, polymers, food product, toxicological properties, etc.
",isbn:"978-1-83768-114-3",printIsbn:"978-1-83768-113-6",pdfIsbn:"978-1-83768-115-0",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"fcd069956c2e931195925b19a74ce9a3",bookSignature:"Dr. Brajesh Kumar",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/12081.jpg",keywords:"Heterocycles Pigments, Azo, Nitro, Indigo, Alizarin, Chromophores, Chromophores, Photochemical, Sulphonation, Diazotisation, UV-Vis Spectroscopy, Metal-Ligand",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"May 19th 2022",dateEndSecondStepPublish:"June 16th 2022",dateEndThirdStepPublish:"August 15th 2022",dateEndFourthStepPublish:"November 3rd 2022",dateEndFifthStepPublish:"January 2nd 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"20 days",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Dr. Brajesh Kumar has worked as a faculty member in various universities in India, Ecuador, and South Korea. 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This chapter deals with this, introducing a method to measure Simplicity.
Design and Engineering are today less an act of drawing or designing something but rather the act of designing a program that in itself conceives a diversity of solutions pertaining to the service or function that we intend to draw or design.
This drawing and designing activity may thus be defined by the creation of new materials; genetic manipulation; software and interface conception; formulation of new forms of languages, mostly those of visualization nature; conception (design) of social, political and cultural ideas; generation of new behaviors with growing complexity.
By opposition and in consequence of complexity and also from the intervention of Design and Engineering we all can access better life quality, we can access better technological artifacts and products while allowing its interaction in a simpler way.
Hence this chapter aims the essence of “simplicity” and how it shows up in several existences, whether it may be in Design, whether it may be in Engineering.
The first time ever someone described how the better organization and functionality of systems can be linked to Simplicity was, in 1870, Claude Bernard (Gene, 2007). However Simplicity, as commonly understood, is not an easy thing to describe, much less to comprehend. What is taken as Simplicity is an undetermined number of concepts to explain what supposedly Simplicity is. The result is a great dispersion that cannot afford reasoning. Some have been able to reduce the given conditions for the existence of Simplicity to ten concepts designated as laws (Maeda, 2006). However we cannot consider it as a definition to describe “simplicity” because such multiplicity is just and only descriptive. If we ought to have a classic image of the state of the art for Simplicity is we can remember the first knowledge of the relation between triangle sides, which was an in-equation:
In-equations have an infinite number of solutions. For millenniums solutions were published with possible triangles. The amount of three side set measures could close in a triangle. So it was until Pythagoras simplicity:
As equations have a finite number of solutions never again was it necessary to write down tables for possible triangles. The comprehension of real space metrics brought up the great growing efficiency to those who design structures. The solution for the problem of knowing if three given measures of line segments would originate a triangle is said to get simplified, and metrics allow simplicity.
Just as in the time when one could only know that the addition of two sides of a triangle was bigger or equal to the length of the third side, to find the solution for simplicity we can also, today, establish tables.
One of the most recent (2006) is that of Maeda. It functions as a synthesis proposal in the rules of Simplicity built in ten laws judged by being different and independent from each other.
This chapter aim is to present a measure for simplicity that will turn it into a parameter central to Design and Engineering.
Until now there are a certain number of rules or laws for Simplicity. The most recent attempt to reduce diversity of notions, Maeda (2006) defines ten laws. But every time we arrive at number ten we cease the main question again. Why ten? Why not eleven or nine? Maeda and his theory of Simplicity suffer from the fact of not having been brought to the Science domain, meaning it has not been made measurable.
Thus this chapter’s object is also to clarify Information’s concepts, taken as data synonymous, stated arguments and rarely faced as Science parameters, either in Design or Engineering, so thus measurable, though observer dependent and relativistic.
In this context, the chapter is meant to suggest, until designers find out about it, that Simplicity can be measurable and can be so from Fisher’s Information Amount (1925) definition. At the same time, the notion will come by that simplicity’s measure is also relativistic yet measurable, thus “mathematizable”, using concepts initiated by Jacob Bernoulli and those more recently funded in mathematics by Dempster and Schafer (1978).
In 1925, Fischer, upon realizing that just as space and time, information is something we all know until someday someone asks us about it. Yet he also knew that physical language description is based in the fact that, whether or not gathering knowledge of its essence, time and space are measurable. With measure one can add measurement, one can establish comparisons; one can recognize solutions, and the future can be sound.
In 1925, before a set of data, Fisher foresaw the possibility of measurement or calculation of information amount over an unknown variable. A set of data gives an information amount over an incognita that can be measurable or calculated. After Fisher, measuring or calculating the information amount that allows a set of data to acquire uncertainty reducing became a possibility. After Fisher it became possible to know if one is acting upon the incognita, guessing, predicting or foretelling.
The method had been established by Jacob Bernoulli back in 1713. In his “The Art of Conjecture” (
We will increasingly use the results from Melo-Pinto (1998) in the recognition technique (the knowing of what the incognita is) and the mathematic method of combining arguments developed by Dempster and Shafer. They both have defined the set for each argument and its weight as a function in the System of Beliefs.
This chapter establishes that for a given System of Beliefs there will be as much simplicity as the lesser the number of data set elements that will be giving the higher amount of information about the incognita.
It will also be concluded that before a same set of data there will be Systems of Beliefs for which there will be higher concentration of information about the incognita.
Hence this chapter is about a measure of Simplicity before a System of Beliefs. Simplicity is as bigger as the smaller the number of elements of the data set that brings the higher quantity of information about the incognita. The relativistic character of Simplicity’s measure will be evidenced as well as how to manage it following from the System of Beliefs’ properties.
In parallel, it will be established that Design concepts, as well as those of Engineering, have been guiding conception’s structuring for Simplicity showing that the concepts expressed in this chapter are not as possible triangles tables were before knowing metrics in Euclid’s space, but rather a metric for Simplicity.
This principle may be sustained by several applications; particularly through the Universal Principals of Design. It is also built upon arguments or data, as proposed by Lidwell et al. (2010), who stated that Design essence is one of the meanings of the artifact that surround us and that we effectively use in our daily life. Hence, we will demonstratehow Design Simplicity is also an Engineering parameter.
Following Claude Bernard, who in 1870 discovered physiologic medicine and stated that
The social and economic impact of information systems in society is a reality in part due to the progress in telecommunications in its most recent shapes: internet, television, computing systems and mobile phones. However a new challenge arouses in the digital era, related either to Design, Engineering, or Technological level application, which consubstantiates the need to attain Simplicity, either of contents, either above all of the designing of related interfaces.
Actually Simplicity is also a quality that not only arouses the passionate devotion for product aesthetics and design, but also became a strategic key tool to allow businesses to confront their own complications (Maeda, 2006).
Hence, we can state that Simplicity is something we all long for… For example to refer to the unquestionable commercial success of Apple’s iPod – a device that has less functionality than others available in the market with the same function: a digital music reader. People want and prefer products they can use with simplicity.
The first time someone described how things are in fact simplicity-related was, back in 1870, Claude Bernard. But simplicity as usually referred can be everything but simple.
According to the meaning pointed out by Portuguese lexical online dictionary (
Quality of what is easy to understand or do: a work’s simplicity;
Luxury absence: to live with simplicity;
Natural, spontaneity: to speak with simplicity.
In the realm of this chapter thus it will be transmitted to the reader the idea that necessarily individuals who work in science have to speak or write or act mandatorily in a complicate and not complex way, makes no sense when one just wants to communicate.
Today, the requirement is to know how to communicate with simplicity, with clarity, interest and repetition, if thus is necessary, to achieve the main goals to transmit understandably (Kotler, 2000).
Already Priest António Vieira, in one of his most important sermons, “
It is this persuasion capacity that by nature is present in human life through different degrees and combinations that allies simplicity and complexity.
But what is effectively Simplicity? Having also apprehended how really complicated it is to establish a measure of Simplicity, Maeda (2006) was able to describe Simplicity in ten (chapters) laws:
To reduce – the simpler way to achieve simplicity is by means of a conscious reduction;
To organize – organization makes a system of many look like a system of few;
Time – time economy transmits simplicity;
Learning – knowledge simplifies everything;
Differences – simplicity and complexity need one another;
Context – what lies in the simplicity’s periphery is definitely non peripheral;
Emotions – more emotions is better than less;
Confidence – in simplicity we trust;
Failure – some things may never be simple;
Singleness – simplicity is to subtract the obvious and to add meaning.
Then he adds three more components, which are:
Distancing – more seems like less simply by going far, far away;
Opening – opening means simplicity;
Energy – use less, win more.
Still according to Maeda, simplifying a design is harder than making it complicated. The great majority of examples he uses are the result of experiences and problems he underwent.
However his considerations about simplicity in life, in business, in Technology or in Design or Engineering, are not to be considered as having been obtained in the basis of a method from a scientific nature.
As well as we do not consider a science that same method of gathering the catalog of squared angles registration that we referred in the framework of this chapter.
It finds out that, as to the meanings of simplicity, we are allowed an infinite variety of data, and as such the information we have is still short, so being before an in-equation as it has an infinite number of solutions.
In this chapter we will be led to know, as Pythagoras did through his theorem, that there is also a way that allows us to be objective, measuring, on the contrary of the description from Maeda (2006), one can describe Simplicity as it has been sustained by Fisher (1925), as the first definition of information amount.
In a predictable future, Simplicity is thus doomed to be Design and Engineering’s motto, of a whole Industry, as it has been featured in it’s own time, the discovery of Pythagoras’s Theorem… Shortly, we aim to give to the reader’s understanding that simplicity is not something intuitive. In fact, today we possess and have access to great data complication, on the other hand the same data are complicated to process, hence we have very little information, which by analogy leads to conclude that if we are facing an enormous simplicity, a few data set will give a great amount of information about the instrument, or the system, or whatever.
Simplicity, like easiness, hardness, information or complication is a matter of the observer’s measuring. It depends on his own system of beliefs.
According to (Drekste, 1999) Information Theory is a branch from probability theory and from statistics mathematics that identifies the amount of Information associated or generated by an event occurrence, or the realization of the state of things, by uncertainty reduction and the elimination of possibilities, presented by the event or by the state of things in question. Relatively to Information “choice” and “amount” are always mentioned and how to measure Information.
Sir Ronald Fisher (1890-1962), a renowned scientist from the 20th century with large contributions to Statistics, Evolutionary Biology and Genetics, introduced in 1925 the concept of Fisher Information, long before the
However, the concept and notion of information is vague and intuitive. When we ask a question, we are requesting data from someone. When we watch a television show or a movie, we are absorbing data. While reading a magazine, or listening to music we know we are dealing with some kind of data. In a general manner, we use, we absorb, we assimilate, we manipulate, we transform, produce and transmit data for as long as our existence.
In 1948, Shannon gave us a more recent definition of Information amount, as the measure of freedom of choice of each one of us when we select a message (data) between all messages of a set.
For Shannon, the content of Information in each message consists only in the quantity of numbers (bits), of zeros and ones leading to the message conveyed. Information can thus be processed as a physical measurable amount.
When we want to transform data into Information, we must bear in mind three basic rules (Snodgrass, 2007):
Organizing data: when confronted with a set of grades these must be numerically ordered;
Data description: when comparing two or more sets of grades these should be referred in the same scale;
Interpreting data: upon seeing punctuation tests in a graphic way one must bear in mind that the visual representation is an interpretation in full respect to numerical tests.
Information and knowledge are the result of human action while aggregating data (symbols or facts) in a social or physical scope, out of context, not directly or immediately significant (signs). Data setting in a determined context acquiring meaning and value, being thus designated as Information. Knowledge comes from the successive accumulation of relevant and structured Information capable of action production, partially based in experience. The data transformation in Information and therefore in knowledge requires a cognitive effort in the perception of the structure and of the allowance of a meaning and a value.
Information can thus be grouped at several “levels” from the most basic shape to the most complex one. In these different levels we refer (Bernoulli, 1713; Quinn, 1980; Waibel and Stiefelhagen, 2009) to:
Context: it is a situation in which something occurs, using any relevant Information to characterize the situation (state description of relevant entities) of an entity that might be a person, a place or an object, to an interaction between a user and an application and including both.
System of Beliefs: as it will be further explained it refers to the arguments and their own weight. The System of Beliefs is relativist, varying from each observer.
Context: the situation in which something happens using any relevant Information to characterize the situation (state description of relevant entities) of an entity that might be a person, a place or an object, for an interaction between a user and an application, and including both.
System of Beliefs: as it will be further explained, it refers to arguments and their relative weight. The System of Beliefs is relativist, varying from the observer.
Objectives: the goals (or the objectives) refer to what we seek to achieve and when we have results to achieve in mind and no reference on how the results must be achieved. It represents what should be obtained but does not specify how to do it.
A possible structure for Information levels is shown above.
According to Porto Editora Portuguese Language Dictionary, the word “sememas” means the signification unit in a lexeme (lexema), which pertains in a set of semes (semas), the minimal significant component of a word.
It is so deductible that the Theory of Information explores the possibility of quantitatively measuring a message’s information to utter analysis of its meaning (Carvalho Rodrigues, 1989).
From this we can conclude that before a set of data it is possible to “know” if it has more or less Information over a variable we do not know but want to know.
In the past, guessing was a possible science, having the objective of trying to determine the meaning and causes of events. With science evolution, guessing was abandoned taking into account only predicament and certainty.
All that is known beyond doubt (Bernoulli, 1713), we claim to know or understand. Relatively to all that is left, we only conjecture and opine. To conjecture about something is the same as to measure the probability of something the best way possible, in order to choose the best option to our judgments and actions.
Randomness is not part of our knowledge but the object’s property, rendering it impossible to make predicaments about it. The probability is a measure of how certain we are and it’s achieved with a combination of arguments. An argument may be defined as a thought to prove or refute a given question.
When an argument fits with mathematics, one can make predictions. When an argument is an image, one can forecast as in “an image is worth a thousand words” as being objective. When one has both arguments (image plus mathematics) one can acquire certainty. Each argument must have a weight and the set of arguments with their relative weight is a System of Beliefs.
Probabilities are estimated by the number and weight of the arguments that prove or indicate that a certain thing is, was or will be. Arguments, by themselves, are intrinsic, or artificial in the daily speech, they are expressed or come out according to considerations of cause, the effects, the observer, the connection, indication or any other circumstances that may have any relation with the thing under proof. It can also be external and non-artificial, coming from the observer’s authority and his or her witnessing.
The way to apply arguments to conjecture and measure probabilities may follow nine rules or axioms:
Applied to things where it is possible to acquire certainty;
It is not sufficient to weigh only one or another argument, but it is necessary to investigate all that may arrive at our knowledge and that is appropriate to prove things;
One must not consider only arguments that prove something but also those that can lead to an opposite conclusion, so that it becomes clear which one has a bigger weight;
In order to judge universalities, remote and universal arguments are enough. However to conjecture about specific things, we must add closer and special arguments if available;
In the uncertainty we must cease all our actions until we have more clarity and, if we have to choose between two possibilities we must make the option for the one that may seem more appropriate, safer, wiser or at least more probable, even if none is.
What is useful and not prejudicial must be preferred over what has never been useful and is always prejudicial;
Human actions must not be evaluated according to the outcome, as, sometimes, imprudent actions have a better result, while reasonable actions may lead to worse results;
In our judgments we must be careful before allowing things getting a bigger weight than they deserve, nor to consider something as less probable than something absolutely certain, nor imposing to others the same opinion;
Once total exactitude can rarely be achieved we consider as absolute certainty only what is morally correct through need and personalized desire.
The System of Beliefs is thus defined as being the set of arguments and their relative weight. Hence, the amount of information allowed by a set of data about an unknown variable depends on the existent System of Beliefs. Therefore with the same set of data we can obtain differentiated results, influenced by the different Systems of Beliefs we all have and that condition the way we see and how we relate to the world.
Another method, stipulating that before a set of data we can obtain higher information amount is to work and focus in the System of Beliefs… For instance, to question and inquire may be boring because it takes to much work and few results in data obtaining.
To investigate the System of Beliefs, we must raise the following questions (Dorbolo, 2003):
Which beliefs do we have?
How do beliefs interrelate?
How do beliefs relate to our feelings and actions?
Which beliefs we have is heavier?
Until how far in past are our beliefs recognizable?
Where did we achieve our beliefs? Did we create them or did we inherit them?
Did we experience big changes in our System of Beliefs? How did that happen?
Is it possible to draw a diagram of a specific cluster of Systems of Beliefs, ideas, feelings or actions?
In short, and the most complete that the set of data is, there will always be a System of Beliefs where the amount of Information over the unknown variable will be zero, due to the limitations of the System of Beliefs in presence of the observer. Many times we are told the way things are but we do not listen.
On the other hand we also have to deal with data uncertainty, as these may be “incomplete, imprecise, fragmented, suspicious, vague, contradictory, or disabled in any other way”.
When we approach the matter of information we cannot avoid the observer’s role. Carvalho Rodrigues advocates that the measure we take from the amount of information in messages received by our senses is based in perception. He gives us the example of two woks from the Russian painter Kasimir Malevitch KasimirMalevitch stated that art’s reality depends entirely from the effect of color over the scenario. The depicted painting has not a relation of subjection to the real world. It is, in itself and by itself a real fact: it is as “concrete” as all objects surrounding us. It means that the object-painting is not imitating anything: it exists, as objects exist in nature.
When we ask what is in those paintings the immediate answer is: A black quadrilateral and a white quadrilateral. However we are before a white canvas in the first painting and a canvas with an almost imperceptible line in the second.
It is exactly over these paintings that that we give the black quadrilateral and the white square higher information amount, because they induce in each one of us feelings which in turn generate action. We also know that “
In this case we were led to conclude that the lesser probability for an event’s occurrence, or yet, the lesser its frequency, the bigger our perception upon it, so the higher the amount of information it contains.
“
It is not surprising that human made creations in the most diversified systems are fragile and precarious and induce great complexity. They are structures influenced too much by non-predictable events, becoming responsible for stronger and everlasting generated perceptions. A system’s structure will only be compatible with a proper information amount, otherwise the structure will enter into collapse and that system will have to organize itself with some other structure.
A system with a great amount of data to obtain less information is said to have a highly disordered structure, and induces in the observer a huge ignorance. On the contrary with an orderly and well organized structure, with a set of data with few elements, one can obtain all the necessary information. In short, the degree of knowledge we can have over a determined system is maximized if its uncertainty is zero.
To do so, a method has been developed to calculate the information amount that events generate in the observer, tested in several domains, in studies related with the loss of cohesion from a society before events related to epidemics, or the effects caused in an army before loss in combat, or still with the detection of faults related to the tannery industry, or the determination of fibers distribution in paper industry.
Hence in this chapter’s realm we are describing a method to measure information amount. The concept of measure enhances the observer’s existence. Hence, the measure of information amount to Simplicity is a relativist measure, it is always dependable on who is effectively observing, because it depends on the observer’s System of Beliefs.
In this sense, the choice of what messages or which messages’ specter to allow measure may take the designation of those messages as relevant factors to a determined structure within a system.
Hence convictions and concepts into which each observer allows importance, are what we designate as a System of Beliefs. Naturally each observer will have his own, and it is single, and by the time the observer is growing through out his own existence and the world around him, he accumulates ever more beliefs and concepts in respect to serials of things.
One of those things would be, for instance, what the Simplicity’s meaning is before a determined individual or group of individuals. Probably meaning can change from one individual to one another. Not in general, but in its specificity, which as we saw can induce to several definitions for Simplicity.
It all depends in the relation on how we perceive and understand the surrounding universe, which takes place in our senses, and naturally in our System of Beliefs. Already mathematician Friederich Bessel, while examining time records on stars transit in Konigsberg observatory, and facing the systematic differences present in observations made by different astronomers, concluded that perhaps he would be before the existence of a “personal equation”. Being thus, one can state that an equation is also a personal experience, and it enhances the existence of a sensor that picks up information transmitted by our senses and that our brain processes.
A sensor is something like a device that receives a signal. It’s associated to a specific sensation. It receives a signal –
In short we can state that sensors are responsible by data transmission to the decision maker that in turn consubstantiates into Information.
As we assessed by Maeda’s (2006) proposal on the concept of Simplicity, the concept of Information as we understood it is also from a relativist or subjective nature, due to the multiplicity and variety of the existent definitions.
We are thus before a probability: the measure of certainty of who we really are, is obtained by the combination of arguments we presently dispose, knowing that there is a weight for each argument. This set of arguments, plus each argument weight is, in turn, the System of Beliefs (Melo-Pinto, 1998). Finally we can also state that before the same set of data, different Systems of Beliefs will also give different results.
Hence that we can sustain Bernoulli’s proposal on arguments combination method, we will now present the results of Melo-Pinto (1998) in the recognition technique (the knowing of what the incognita is) by the mathematical method of combining arguments afterwards developed by Dempster-Shafer (Yager, 1994). They have both defined the set of each argument and its weight as function constituents of the System of Beliefs.
Schools, either from Design or Engineering, were created as to allow the same school’s System of Beliefs to deal with design or the design with the fewer possible data.
The question now raised is how in Design or Engineering we built a System of Beliefs to allow design or the design simpler in itself and for users? We can state that it can be made through combined arguments or weights that are part of the System of Beliefs.
According to Melo-Pinto (1998), decision process results from information gathering driven to that decision. But all along, the natural appearance of new arguments (partial or not) may drove us to remake beliefs by the light of new data.
Still according to Melo-Pinto (1998), who developed a system of decision making applied to the visual recognition of images in degrading situations, he states that
“Design Universal Principles” may be those “arguments” than can be embodied as Design essence. They are, no less, and according to Lidwell et al. (2010), the meanings we give to the artifacts we use, in usability terms as well as in its influence, perception and usage call in everyday life, and can assume their selves as combined data and arguments.
As seen before, different arguments combining with a specific weight is what embodies our system of beliefs.
The issue we could now raise in this chapter is what is the reason why some products are most desired by some certain people over others? Which method could be used as to allow knowing which arguments each one of us gives more or less relevance?
Today we know that the supposed commercial failure of some products is due not only to problems related to an operative-functional nature, but also because they didn’t made sense to the aimed target. Hence we can state that this is a consequence of something that does not fit with the positivist perception of a certain user.
In that sense, this chapter now aims to let know the “Design Universal Principles” (Lidwell et al., 2010), as a first guide to interdisciplinary reference not only to designers but also to engineers as it combines a vast set of arguments in the shape of 125 concepts related to Design and also to Psychology, Engineering and Architecture, organized through five categories, it can be used as a guide to structure the conception for Simplicity, not only for Design, but also as a reference for Engineering:
How can Design and Engineering’s perception be influenced?
How to help people learn about Design and Engineering?
How to improve Design and Engineering’s usability?
How to raise the call for Design and Engineering?
How to improve decision taking in Design and Engineering processes?
These five categories are in turn subdivided into 225 contents that raise questions as diversified as: accessibility, archetypes, linings, cognitive dissonance, color, comparison, confirmation, consistence, convergence, cost-benefice, development cycle, errors, safety factor, Fibonacci’s sequence, figure-background relation, usability-flexibility, forgetting, form and function, Gutenberg’s diagram, hierarchy, highlight, iconic representation, interference effects, Prägnanz’ law, legibility, life cycle, mental map, modularity, normal distribution, among many other, and truly it reflects a decision process, as it has the capacity to combine some of the mentioned arguments that may simplify processes while elaborating a Design or Engineering design.
But is it possible, as we call upon those 225 principals, that we became paralyzed while design acting? After all, where to start designing, which or what aspect should we allow more or less importance? Supposedly hardly anybody will be able give the answer. Even so, believing the existence of those “beliefs”, there can only be, at the most, one or two… Hence, assuring the 225 (152) “principals” will not be in fact a statement to consider.
What will make sense is to state, that at the most, there was someone who described 225 arguments or weights to build or describe his own system of beliefs.
Hence the concept of Simplicity in Design or Engineering is the one in which effectively each observer beliefs as its own, and that it naturally depends on the amount of information he has relatively to the data he possesses, as the result of combining different arguments or data:
Set of data
Set of data
Maximum Information Amount given by set of data
Maximum Information Amount given by set of data
Before a system of beliefs
Before a system of beliefs
If
If
If
The same is applied to the set of data
If
It indicates that for the system of beliefs
If
If
If
If
If
In conclusion we can state that for the same system of beliefs the set that gives higher information amount is the simpler.
For the same set of data the system of beliefs that allows a set of higher information amount about the incognita is the most adequate to predict.
One can thus deduct that simpler is what needs less number of elements or set of data to obtain the same information amount or even higher.
This is the essence of Simplicity, and it can be sustained in “Design Universal Principles”, in the quality of an interdisciplinary reference guide, either in Design as in Engineering.
However and as complete as it may be, the set of data that can be involved in the conception of a project of Design or Engineering there will also and always be present a System of Beliefs built over a given observer, to whom the information amount over the unknown variable will be zero, as also, there will be a system of beliefs that before a very incomplete set of data will obtain the maximum information amount over the unknown variable.
We can thus deduce that Design in particular and its several schools are liable to be related to mathematics. That schools are a system of beliefs, and they must be not simply a place for knowledge transmission but also a place that promotes knowledge emergence associated to Simplicity.
We will be, as much, before arguments or weights that each School created to give sense to its own design, in this case having as basis the combining arguments according to Dempster-Shafer theory.
Truly a designer can assign determined values to the arguments or weights in cause and another designer can assign to the same arguments or weights another set of values.
Hence Design is no longer a derivation from art, not even from object engineering (MOURA, 2012). Design can be what informs about human creativity, that emerges from the combination and interaction between the several fields of creativity itself, to what we would like to add that it depends on the combining of different arguments and weights of the system of beliefs to what that designer pertains and that will always be the one he received in its School as a student.
We here designate as pertaining to a same school all those who share the same arguments with the same weight.
Hence we can state that we can have as much Schools or Systems of Beliefs as the nature of arguments (
So that a School can be shaped:
when:
The result is that a System of Beliefs is a School, a cluster, and it shares the same arguments with the same weight allowed to the same arguments:
Hence we can deduce that Schools have the gift to simplify things. And that the set of data or arguments is equal to
In conclusion, some aspects can be evidenced:
The essence of the meaning of “Simplicity” is not one of easy understanding in the way it has been, so far, described. The common knowledge is that there are undetermined number of definitions to explain what effectively is Simplicity;
That “Simplicity is relativist”, as an example of “easiness”, of “difficultness”, of “information”, or “complexity”, among others, are issues of each one measurements. As a system of beliefs it will always be associated with the observer.
That like “Simplicity”, until now the concept or notion of “Information” is vague and intuitive.
That before a huge Simplicity, we will be before a major amount of information, with restricted data;
That Design in particular and its several schools are also passable of “mathematization”;
That Maeda’s laws to describe “Simplicity” are a set of arguments and weights built in Maeda’s System of Beliefs;
At last that a school is always committed to its shared System of Beliefs, and as such it is responsible for values, ideals, feelings and actions transmitted to those who are or were, part of itself.
In conclusion we can also state that Maeda’s laws are not effectively laws, but methods or suggestions to define simplicity, because as we saw the simplicity measure explained does not need further increase.
Hence, if we use this relativist measure for simplicity coupled with the complexity measure, we then have the quantitative parameters that release us of qualitative laws for engineering or for design. They allow us the necessary amount to assess design, or engineering, or both.
Therefore the encounter between complexity and simplicity is an art, once we are capable of measuring it and, as such, to quantify it, we acquired the necessary tools for either an engineer or a designer, to achieve the objective of conceiving and build concepts, methods, processes or products, either organic or functional, and hence, at the very end this is what an engineer or a designer aims to. Complexity and simplicity is an art over which we are capable to put measures and, as such, to quantify.
In conclusion we dare state that if we were in the presence of a philosopher; he would say that the true definition for simplicity would be: it exists as to make sense within the world that surrounds us.
It will be then demonstrated that “Simplicity” (its measurement) in particular that of Design, being measurable, is also an Engineering parameter.
Thanks to:
Professor F. Carvalho Rodrigues was responsible for encouraging and helped me the fulfillment of this vision.
Martim Lapa, for his admirable staying power to support me to translate this version.
Professor Denis A. Coelho for editing the manuscript.
Finally, I would also like to thank the UNIDCOM/IADE.
The EEG is a neuroimaging device that reflects the electrophysiological activity of the cerebrum that is generated by the synchronistic firing of nerve cells [1, 2]. Because the EEG reflects dynamic neurocognitive processes according to millisecond variations, the statistical properties of neural activation and processes fluctuate according to time, depth, and orientation of the neural generators. Measurement of the electrical activity reflected by the EEG is best conceptualized as a nonlinear stochastic process that is inherently spatio-temporally dependent [1, 2].
Extracellular currents are derived from excitatory and inhibitory postsynaptic potentials allow for dipole moment per unit volume approximations [1, 3]. The dipole moment per unit volume approximations allow for the derivation of weighted estimations of current source density according to neural generators across and between local tissues and the orthogonal orientation of nerve cells within the neocortical layers [1].
While measurements of extracellular currents can be measured using divergent mathematical algorithms (i.e., phase shift, phase lock, coherence, and lagged coherence), the interaction between neurons that generate excitatory and inhibitory postsynaptic potentials must be evaluated according to time, frequency, and the location of the neural generators [4, 5]. Utilization of the Fast Fourier Transformation (FFT) allows for the derivation of EEG frequency bands from the raw signal according to time. FFT analyses elucidate phase angle and phase differences from the EEG frequency domains. When the phase angle is stable or constant, this indicates that coherence = 1.0 whereas coherence = 0 when there are phase differences due to moment to moment variations in the phase angle. Thus, coherence elucidates communication between distal and contiguous neuroanatomical regions and therefore, across and between functional networks via coupled neural oscillators [4, 5].
Mathematical modeling of current sources can be reflected as
Applications of Maxwell’s equations to the EEG incorporate fundamental principles related to thermodynamics as derived by Faraday’s law of electromagnetic induction and Gauss’ law of electromagnetism [11, 12, 13, 14]. Maxwell’s equations establish that the electrical displacement of neural generators and the field produced by these neurophysiological generators inherently influence accurate estimations of current source density [14].
There are four algorithms that comprise Maxwell’s equations [15, 16, 17]. Eq. (1) defines 𝛁 as a nabla operator [14]. The nabla must act upon the other variables denoted within the equation in order to derive estimations of current source density.
Considerations of Eq. (1) indicate that the nabla operator denotes a gradient of a scalar field when this operator is utilized to derive estimations of neural generators according to a Cartesian coordinate system [15]. Thus, this equation attempts to utilize statistical weighting to estimate Laplacian operators that are derived from electromagnetic fields at different points within the head volume conduction model. Because the activity reflected in an EEG recording is derived from the activity of orthogonally oriented neurons, estimations of current source density must account for the errors in estimation that are a result of the inability to determine the precise location of the neurobiological generators that produce dipole magnetic fields [15]. It is important to denote that 𝛁 x
Eq. (2) indicates that the cross product between the magnetic field strength,
Eq. (3) indicates that the gradient of a scalar field as a cross product between the electrical displacement,
Applications of Maxwell’s law and Gauss’ law of electromagnetism incorporate the divergence theorem [17]. The divergence theorem states that the properties of a continuous entity, such as electrical flux, within a closed circuit is equal to the spread of that continuous entity over the volume of the closed-circuit system. Thus, because the flow of a continuous entity must be calculated as a 3-dimensional dispersion, the calculation must consider the magnitude, directionality, and the time by which the divergence occurs. This theorem indicates that a geometric interpretation of the dispersion of a waveform that uses a 3-coordinate configuration system is equivalent to the derivation of current source density [17].
Eq. (4) indicates that the sum of the voltages within a closed-circuit loop must inherently sum to zero [15]. This assertion is consistent with Laplacian physics and Kirchhoff’s Circuit Theory [18].
Geometric models and calculus-based physics in EEG source localization include applications of Coulomb’s inverse-square law [19]. Coulomb’s law indicates that the magnitude of the electrical force between two particles is inversely related to the distance between the two charges. Thus, as distance increases, the magnitude of the two charges decrease. This law also indicates that electrical force increases as the charge of two particles increase. Coulomb’s law can be applied to estimations of source localization if the difference in magnitude between divergent neural generators is considered similarly to the difference in charge of two particles. Specifically, as the distance between electrophysiological generators from the scalp increases, there is a decreased probability that this activity will be reflected on the surface. Coulomb’s inverse square law is mathematically defined in Eq. (5) [19].
Because the depth of a signal inherently influences the electrical field within a volume conductor, applications of Ohm’s law to the EEG are also related to source localization [19]. Algorithmic modeling of Ohm’s law can be reflected according to vector computations. Eq. (6) denotes that
Gradient derivations are also employed to evaluate the Laplacian operators [19, 20]. Estimations of Cartesian coordinates to evaluate locations of electrical generators are determined by computations that derive the statistical term weights in vector space models. Eq. (7) indicates that the electrical field is computed as a vector function that fluctuates according to time. The derivation of the estimated coordinates account for the time and direction of the magnetic field which inherently affects the magnitude of power reflected by electrical generators. Eq. (7) defines
Computations of Laplacian operators require considerations of resistivity [1, 10, 21]. Because the resistivity of biologic materials within the EEG are anisotropic, estimations of Laplacian operators according to the head volume conduction model are inherently flawed. The head volume conduction model assumes isotropy or uniform conductivity. Weighted approximations of the resistivity within a biologic medium must account for the time, region, directionality and the type of tissue by which the electrical currents propagate. Because electrical currents indicate a non-uniform distribution, a cross-section within the brain may present divergent resistive properties dependent upon the Laplacian operator being cortical or subcortical in origin [21].
Further applications of Maxwell’s equations include the Maxwell-Rayleigh algorithm [21]. This algorithm is utilized to calculate the resistive properties that occur within a spherical conductive model. Thus, the Maxwell-Rayleigh equation incorporates geometric configurations to estimate of gradations of resistivity that are attributable to a homogenous suspension that exists within a volume conductor. This application is directly related to the estimation of current source density as the brain is surrounded by cerebrospinal fluid. Eq. (8) defines
Considerations of algorithms that attempt to model estimations of current source density according to the EEG must consider physiological constraints and mathematical limitations [1]. Derivations of the cumulative density function according to Eq. (9) does not consider the resistivity of the biological material by which the electrical signals must bypass. The resistivity of these biological materials alters the conductivity of the electrical signals that are reflected on the scalp. Eq. (9) defines
Applications of quantum mechanics indicate that linear models that are utilized to conceptualize EEG data are inherently flawed [22]. Linear models that attempt to model EEG signals according to volume conduction include the linear instantaneous time-invariant mixing algorithm [23]. The linear instantaneous time-invariant mixing model indicates that the generation of electrophysiological signals can be modeled as a linear function. This is attributable to the assertion that the cumulative electrical activity reflected on the scalp is a result of the mixing of underlying sources within the head volume conduction model. Congedo and Sherlin [23] indicate that the mixing coefficients or the individual sources do not vary according to time and are therefore fixed. Eq. (10) defines xi as the voltage,
Eq. (10) negates the inclusion of factors related to the resistivity of the biologic medium by which the electrical signals are derived [23]. Furthermore, this equation is inherently flawed in that the mixing coefficients are deemed as time invariant factors. Considerations of the inverse problem and Coulomb’s law of electrical force indicate that the estimation of the electrical sources is dependent upon the depth, orientation, and number of neurons that generate the EEG rhythms that are reflected on the scalp [1, 7].
Applications of Heinsenberg’s Uncertainty Principle and Schrodinger’s equation further exemplify the error associated with conceptualizing the EEG as a linear function [22, 24]. These principles and algorithms indicate that EEG waveforms can be modeled as a summation of individual waves and quantum particles. Heinsenberg’s Uncertainty Principle indicates that statistical modeling can be utilized in a priori estimations of the location and position of quantum objects as the precise location and momentum of particles cannot be simultaneously determined. Eq. (11) is a representation of the time independent derivative of the Schrodinger equation [22, 24].
Eq. (11) defines
The Schrodinger equation exemplifies the inherent limitations of the head volume conduction model and, therefore, the inverse problem. Albeit Nunez and Srinivasan [21] have derived estimations of resistivity for divergent biological materials such as the skull, cerebrospinal fluid, dura, blood and the cortex, the Schrodinger equation indicates that the precise location of individual quantum particles and waveforms cannot be determined unless invasive procedures are utilized to isolate these particles [21, 22]. Postulates of the Schrodinger equation indicate that probability distributions are utilized to estimate the dispersion of each wave form [24]. This postulate can be applied to the EEG in relation to the derivation of dipole magnetic fields.
Because multiple ‘neurorhythmicities’ are generated at any given time, where each waveform will have its own probabilities and estimated dispersions of the dipole fields related to that wave, there is not a unique solution to the inverse problem. Derivation of the individual statistical weights for each waveform that is cortical or subcortical in origin is mathematically infeasible. These mathematical and physiological challenges that are specific to the head volume conduction model and inverse problem indicate the necessity to incorporate integrals and imaginary components to reduce statistical error in estimations of source localization.
The classification of EEG waveforms as continuous or discrete quantum matter and the output of the EEG as a linear or nonlinear function inherently affects algorithmic modeling for estimations of source localization [23, 24]. While Nunez and Srinivasan [21] have estimated the degree to which specific biologic mediums and materials possess resistive properties, these parametric configurations do not provide a solution to the inverse problem. Applications of quantum mechanics indicate that neurodynamic behavior that originates in thalamo-cortical compared to cortico-cortical regions yield divergent 3-dimensional dispersions of wave forms and quantum energy [21].
The area of tissue by which the oscillatory mechanisms are thought to originate inherently determines the validity and applicability of Ohm’s law to the EEG [1]. Specifically, the amount of tissue by which the neuro-oscillatory generators are thought to be dispersed distorts mathematical estimations of source localization. As the magnitude of space where neural generators are thought to originate increases, Ohm’s law may only be applicable when estimates of current source density are calculated using matrices to account for the macroscopic and anisotropic heterogeneities that permeate calculations of resistivity in subcortical and cortical regions [21].
Applications of the Schrodinger equation and Heisenberg’s Uncertainty Principle indicate that if EEG waveforms are considered as a summation of discrete particles and individual waveforms, the precise cytoarchitectural boundaries and power of the specific quantum particles that comprise these waveforms cannot be derived simultaneously. Estimations of current source density must obey laws of physics related to thermodynamics and electromagnetism. Thus, laws of classical physics and quantum mechanics such as Coulomb’s inverse square law, Gauss’s law of electromagnetism, and Maxwell’s equations can be applied to derive estimations of the Cartesian coordinates that are utilized in 3-dimensional dipole electrical field per unit volumetric estimations of current source density [1, 19].
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As the science gets more advanced and the information about these two points becomes clearer, the view of this information might modify our understanding to these processes. Then, some topics might be dropped, and others might be raised or become more obvious. However, the feeding of halophyte forages as per se has several drawbacks and therefore, they have to be fed in mixed rations, fortifying these rations with energy supplements.",book:{id:"5978",slug:"new-perspectives-in-forage-crops",title:"New Perspectives in Forage Crops",fullTitle:"New Perspectives in Forage Crops"},signatures:"Salah A. 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CW has been successfully applied as an adsorbent for removing pollutants from wastewater and gas, a precursor for obtaining activated carbon, and a feedstock for producing energy and valuable products using mono-process extraction and biorefinery.",book:{id:"8952",slug:"coffee-production-and-research",title:"Coffee",fullTitle:"Coffee - Production and Research"},signatures:"Felipe J. Cerino-Córdova, Nancy E. Dávila-Guzmán, Azucena M. García León, Jacob J. Salazar-Rabago and Eduardo Soto-Regalado",authors:null},{id:"56029",doi:"10.5772/intechopen.69614",title:"Production of Spineless Cactus in Brazilian Semiarid",slug:"production-of-spineless-cactus-in-brazilian-semiarid",totalDownloads:1889,totalCrossrefCites:4,totalDimensionsCites:8,abstract:"The term “spineless cactus” is used in Brazil to designate cultivars of Opuntia ficus indica Mill and Nopalea cochenillifera Salm Dyck. The spineless cactus was consolidated in Brazilian semiarid as a strategic fundamental food resource in several production livestock systems, constituting a plant with enormous productive potential. Thus, the spineless cactus has been widely cultivated and used for several decades, by enabling the animal feeding in critical periods of year because of its characteristics, morpho‐anatomical and physiological (CAM), which makes it tolerant to long droughts, being a crop that presents high productivity in droughts conditions, when compared to other forages. Nevertheless, the spineless cactus is a crop relatively picky about soil and climate characteristics of region, presenting greater growth in fertile soils, as well as in regions where nighttime temperatures are cool and the air humidity is relatively high. Although the crop be adapted to long droughts periods, many times it’s necessary to perform irrigation in its production system, mainly in regions of low rainfall, for to supply its water needs, thus ensuring productivity and survival of crop. Therefore, the knowledge of characteristics of plant, as well as of appropriate management techniques to crop, is essential for the good performance of spineless cactus.",book:{id:"5978",slug:"new-perspectives-in-forage-crops",title:"New Perspectives in Forage Crops",fullTitle:"New Perspectives in Forage Crops"},signatures:"Wilma Cristina Cavalcante dos Santos Sá, Edson Mauro Santos,\nJuliana Silva de Oliveira and Alexandre Fernandes Perazzo",authors:[{id:"139631",title:"Dr.",name:"Edson Mauro",middleName:null,surname:"Santos",slug:"edson-mauro-santos",fullName:"Edson Mauro Santos"},{id:"180036",title:"Dr.",name:"Juliana",middleName:null,surname:"Oliveira",slug:"juliana-oliveira",fullName:"Juliana Oliveira"},{id:"203022",title:"MSc.",name:"Wilma",middleName:null,surname:"Sá",slug:"wilma-sa",fullName:"Wilma Sá"},{id:"207265",title:"Dr.",name:"Alexandre",middleName:null,surname:"Perazzo",slug:"alexandre-perazzo",fullName:"Alexandre Perazzo"}]},{id:"70151",doi:"10.5772/intechopen.89224",title:"The Harvest and Post-Harvest Management Practices’ Impact on Coffee Quality",slug:"the-harvest-and-post-harvest-management-practices-impact-on-coffee-quality",totalDownloads:1802,totalCrossrefCites:3,totalDimensionsCites:7,abstract:"Coffee is one of the most important agricultural commodities in the world. The coffee quality is associated with pre-harvest and post-harvest management activities. Each step starting from selecting the best coffee variety for plantation until the final coffee drink preparation determines the cupping quality. The overall coffee quality influenced by the factors which involve in changes the physicochemical properties and sensorial attributes, including the post-harvest operations. The post-harvest processing activities contribute about 60% of the quality of green coffee beans. The post-harvest operations include pulping, processing, drying, hulling, cleaning, sorting, grading, storage, roasting, grinding, and cupping. This chapter comprises the harvest and post-harvest operations of coffee and their impacts on coffee quality.",book:{id:"8952",slug:"coffee-production-and-research",title:"Coffee",fullTitle:"Coffee - Production and Research"},signatures:"Mesfin Haile and Won Hee Kang",authors:null},{id:"69900",doi:"10.5772/intechopen.89508",title:"Coffee By-Products: Nowadays and Perspectives",slug:"coffee-by-products-nowadays-and-perspectives",totalDownloads:1148,totalCrossrefCites:3,totalDimensionsCites:6,abstract:"Coffee is one of the most consumed products around the world; 2.25 billions of coffee cup are consumed everyday in the world. For coffee crop production, different by-products are produced, such as coffee peel, coffee husk, parchment, and spent coffee grounds. These by-products have several problems associated at the final disposition. In this book chapter, we study the main coffee varieties produced in the world, the by-products produced, and its composition and finally assess the potential of supramolecular solvents (SUPRAS) and water as green solvents for high-added-value compound extractions. Bioactive compounds were extracted from fresh and dried coffee peel in an acceptable rate for industrial applications. SUPRAS offer advantages in terms of rapidity (5 min) and simplicity (stirring and centrifugation at room temperature), thus avoiding costly processes based on high pressure and temperature. Extractions carried out using water as solvent is another technique of extraction mixing temperature (above 60°C) and time (4.5 min) obtained a beverage or solution with presence a bioactive compounds how caffeine, chlorogenic acid and polyphenols.",book:{id:"8952",slug:"coffee-production-and-research",title:"Coffee",fullTitle:"Coffee - Production and Research"},signatures:"Laura Sofía Torres-Valenzuela, Johanna Andrea Serna-Jiménez and Katherine Martínez",authors:null}],mostDownloadedChaptersLast30Days:[{id:"71528",title:"A Detail Chemistry of Coffee and Its Analysis",slug:"a-detail-chemistry-of-coffee-and-its-analysis",totalDownloads:2331,totalCrossrefCites:5,totalDimensionsCites:6,abstract:"This review article highlights the detailed chemistry of coffee including its components; chemical constituents like carbohydrates, proteins, lipids, and caffeine; aromatic principles; oil and waxes; and minerals and acids. The high extent of caffeine can be found in the coffee plants; hence, in the second part of the study, various analytical methods are designed for the proper identification, separation, optimization, purification, and determination of caffeine present in coffee, tea, and marketed coffee. These analytical methods are appropriated for the separation and quantification of caffeine. The various analytical methods include spectroscopy methods like UV, IR, and NMR spectroscopy; chromatographic methods like paper, TLC, column, HPLC, and gas chromatography; and hyphenated techniques like LC–MS, GC–MS, and GC–MS/MS. This article compares and contrasts the amount of caffeine by various analytical methods.",book:{id:"8952",slug:"coffee-production-and-research",title:"Coffee",fullTitle:"Coffee - Production and Research"},signatures:"Hemraj Sharma",authors:null},{id:"70151",title:"The Harvest and Post-Harvest Management Practices’ Impact on Coffee Quality",slug:"the-harvest-and-post-harvest-management-practices-impact-on-coffee-quality",totalDownloads:1793,totalCrossrefCites:3,totalDimensionsCites:7,abstract:"Coffee is one of the most important agricultural commodities in the world. The coffee quality is associated with pre-harvest and post-harvest management activities. Each step starting from selecting the best coffee variety for plantation until the final coffee drink preparation determines the cupping quality. The overall coffee quality influenced by the factors which involve in changes the physicochemical properties and sensorial attributes, including the post-harvest operations. The post-harvest processing activities contribute about 60% of the quality of green coffee beans. The post-harvest operations include pulping, processing, drying, hulling, cleaning, sorting, grading, storage, roasting, grinding, and cupping. This chapter comprises the harvest and post-harvest operations of coffee and their impacts on coffee quality.",book:{id:"8952",slug:"coffee-production-and-research",title:"Coffee",fullTitle:"Coffee - Production and Research"},signatures:"Mesfin Haile and Won Hee Kang",authors:null},{id:"72400",title:"Factors Affecting Efficiency of Vegetable Production in Nigeria: A Review",slug:"factors-affecting-efficiency-of-vegetable-production-in-nigeria-a-review",totalDownloads:803,totalCrossrefCites:0,totalDimensionsCites:2,abstract:"Vegetables are important for maintenance of good health; their production and marketing are veritable sources of employment and livelihood. To promote vegetables’ contribution to the above, there is a need for sustainable and efficient production process. The paper reviewed production, socioeconomic factors, and constraint affecting efficiency of production of three important vegetables (tomato, pepper, and onion). The review showed that socioeconomic factors found to increase technical efficiency in vegetable production were educational level, extension contact, and household size. Influence of farmer age on technical efficiency was inconclusive due to varied opinions. Increase in farm size, quantity of seed, amount of fertilizer, and agrochemical were found to have positive influence on output. Majority of the literature reviewed opined that increase in quantity of labour raises productivity; however, it must be utilized efficiently. The mean technical efficiency of the vegetables varied from the southern to the northern part of the country. The cross cutting constraints in vegetables production are pest and diseases, inadequate storage facilities, and high cost of improved inputs. The study recommends increase awareness and sensitization on optimum levels of resource use for increased productivity and appropriate intervention to constraints in the value chain.",book:{id:"10142",slug:"agricultural-economics",title:"Agricultural Economics",fullTitle:"Agricultural Economics"},signatures:"Iyabo Bosede Adeoye",authors:[{id:"317695",title:"Dr.",name:"Iyabo Bosede",middleName:null,surname:"Adeoye",slug:"iyabo-bosede-adeoye",fullName:"Iyabo Bosede Adeoye"}]},{id:"65591",title:"Insect Pest Management in Organic Farming System",slug:"insect-pest-management-in-organic-farming-system",totalDownloads:2595,totalCrossrefCites:1,totalDimensionsCites:4,abstract:"Due to the regulations of organic farming, few options remain for organic farmers to manage pests and diseases in their crops compared to conventional farming. However, major pests could still be managed through manipulation of the agroecosystem processes in advantage of the crops and disadvantage of pests. The limited number of active plant protection substances authorized for use in organic farming can provide support to natural and biological control agents in suppression of pests and diseases. This chapter highlights the principles and strategies of crop protection in organic farming, the cultural practices adopted, the active substances allowed for use to suppress pests, and the impacts on faunal and floral biodiversity. A case study of organic date palm cultivation is discussed.",book:{id:"6988",slug:"multifunctionality-and-impacts-of-organic-and-conventional-agriculture",title:"Multifunctionality and Impacts of Organic and Conventional Agriculture",fullTitle:"Multifunctionality and Impacts of Organic and Conventional Agriculture"},signatures:"Hamadttu Abdel Farag El-Shafie",authors:[{id:"192142",title:"Dr.",name:"Hamadttu",middleName:null,surname:"El-Shafie",slug:"hamadttu-el-shafie",fullName:"Hamadttu El-Shafie"}]},{id:"69412",title:"Soil Management and Water-Use Efficiency in Brazilian Coffee Crops",slug:"soil-management-and-water-use-efficiency-in-brazilian-coffee-crops",totalDownloads:806,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Brazil is a world leader in coffee production. However, currently, it coexists with recurrent and severe droughts, accompanied by intense heat, strong insolation and low relative humidity. As the cultivation is carried out primarily in the rainy season, these world climate variations have affected crops yields and fruits quality, requiring innovative actions that promote efficient use of water stored in the soil. Among several soil management practices that promote a more rational use of water, deep tillage combined with liming, gypsum and fertilizer amendments lead to an increase in effective depth of coffee roots, therefore reducing water stress. Moreover, intercropping with Urochloa sp. is highly efficient in enhancing soil structure, water infiltration and plant available water capacity. Additionally, other innovative techniques and practices are also introduced in this chapter.",book:{id:"8952",slug:"coffee-production-and-research",title:"Coffee",fullTitle:"Coffee - Production and Research"},signatures:"Bruno Montoani Silva, Geraldo César de Oliveira, Milson Evaldo Serafim, Carla Eloize Carducci, Érika Andressa da Silva, Samara Martins Barbosa, Laura Beatriz Batista de Melo, Walbert Junior Reis dos Santos, Thiago Henrique Pereira Reis, César Henrique Caputo de Oliveira and Paulo Tácito Gontijo Guimarães",authors:null}],onlineFirstChaptersFilter:{topicId:"27",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:320,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:133,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:16,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. 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Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. 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He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:38,paginationItems:[{id:"82531",title:"Abnormal Iron Metabolism and Its Effect on Dentistry",doi:"10.5772/intechopen.104502",signatures:"Chinmayee Dahihandekar and Sweta Kale Pisulkar",slug:"abnormal-iron-metabolism-and-its-effect-on-dentistry",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Iron Metabolism - Iron a Double‐Edged Sword",coverURL:"https://cdn.intechopen.com/books/images_new/10842.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82291",title:"The Role of Oxidative Stress in the Onset and Development of Age-Related Macular Degeneration",doi:"10.5772/intechopen.105599",signatures:"Emina Čolak, Lepša Žorić, Miloš Mirković, Jana Mirković, Ilija Dragojević, Dijana Mirić, Bojana Kisić and Ljubinka Nikolić",slug:"the-role-of-oxidative-stress-in-the-onset-and-development-of-age-related-macular-degeneration",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Importance of Oxidative Stress and Antioxidant System in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/11671.jpg",subseries:{id:"15",title:"Chemical Biology"}}},{id:"82195",title:"Endoplasmic Reticulum: A Hub in Lipid Homeostasis",doi:"10.5772/intechopen.105450",signatures:"Raúl Ventura and María Isabel Hernández-Alvarez",slug:"endoplasmic-reticulum-a-hub-in-lipid-homeostasis",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"82409",title:"Purinergic Signaling in Covid-19 Disease",doi:"10.5772/intechopen.105008",signatures:"Hailian Shen",slug:"purinergic-signaling-in-covid-19-disease",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}}]},overviewPagePublishedBooks:{paginationCount:32,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. Waisundara",profilePictureURL:"https://mts.intechopen.com/storage/users/194281/images/system/194281.jpg",biography:"Dr. Viduranga Waisundara obtained her Ph.D. in Food Science\nand Technology from the Department of Chemistry, National\nUniversity of Singapore, in 2010. She was a lecturer at Temasek Polytechnic, Singapore from July 2009 to March 2013.\nShe relocated to her motherland of Sri Lanka and spearheaded the Functional Food Product Development Project at the\nNational Institute of Fundamental Studies from April 2013 to\nOctober 2016. She was a senior lecturer on a temporary basis at the Department of\nFood Technology, Faculty of Technology, Rajarata University of Sri Lanka. She is\ncurrently Deputy Principal of the Australian College of Business and Technology –\nKandy Campus, Sri Lanka. She is also the Global Harmonization Initiative (GHI)",institutionString:"Australian College of Business & Technology",institution:null}]},{type:"book",id:"6820",title:"Keratin",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6820.jpg",slug:"keratin",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Miroslav Blumenberg",hash:"6def75cd4b6b5324a02b6dc0359896d0",volumeInSeries:2,fullTitle:"Keratin",editors:[{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. 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He has published more than 50 papers in journals and 2 books.",institutionString:null,institution:{name:"Universitas Internasional Batam",country:{name:"Indonesia"}}},{id:"314576",title:"Dr.",name:"Ibai",middleName:null,surname:"Laña",slug:"ibai-lana",fullName:"Ibai Laña",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314576/images/system/314576.jpg",biography:"Dr. Ibai Laña works at TECNALIA as a data analyst. He received his Ph.D. in Artificial Intelligence from the University of the Basque Country (UPV/EHU), Spain, in 2018. He is currently a senior researcher at TECNALIA. His research interests fall within the intersection of intelligent transportation systems, machine learning, traffic data analysis, and data science. He has dealt with urban traffic forecasting problems, applying machine learning models and evolutionary algorithms. He has experience in origin-destination matrix estimation or point of interest and trajectory detection. Working with large volumes of data has given him a good command of big data processing tools and NoSQL databases. He has also been a visiting scholar at the Knowledge Engineering and Discovery Research Institute, Auckland University of Technology.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"314575",title:"Dr.",name:"Jesus",middleName:null,surname:"L. Lobo",slug:"jesus-l.-lobo",fullName:"Jesus L. Lobo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314575/images/system/314575.png",biography:"Dr. Jesús López is currently based in Bilbao (Spain) working at TECNALIA as Artificial Intelligence Research Scientist. In most cases, a project idea or a new research line needs to be investigated to see if it is good enough to take into production or to focus on it. That is exactly what he does, diving into Machine Learning algorithms and technologies to help TECNALIA to decide whether something is great in theory or will actually impact on the product or processes of its projects. So, he is expert at framing experiments, developing hypotheses, and proving whether they’re true or not, in order to investigate fundamental problems with a longer time horizon. He is also able to design and develop PoCs and system prototypes in simulation. He has participated in several national and internacional R&D projects.\n\nAs another relevant part of his everyday research work, he usually publishes his findings in reputed scientific refereed journals and international conferences, occasionally acting as reviewer and Programme Commitee member. Concretely, since 2018 he has published 9 JCR (8 Q1) journal papers, 9 conference papers (e.g. ECML PKDD 2021), and he has co-edited a book. He is also active in popular science writing data science stories for reputed blogs (KDNuggets, TowardsDataScience, Naukas). Besides, he has recently embarked on mentoring programmes as mentor, and has also worked as data science trainer.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"103779",title:"Prof.",name:"Yalcin",middleName:null,surname:"Isler",slug:"yalcin-isler",fullName:"Yalcin Isler",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRyQ8QAK/Profile_Picture_1628834958734",biography:"Yalcin Isler (1971 - Burdur / Turkey) received the B.Sc. degree in the Department of Electrical and Electronics Engineering from Anadolu University, Eskisehir, Turkey, in 1993, the M.Sc. degree from the Department of Electronics and Communication Engineering, Suleyman Demirel University, Isparta, Turkey, in 1996, the Ph.D. degree from the Department of Electrical and Electronics Engineering, Dokuz Eylul University, Izmir, Turkey, in 2009, and the Competence of Associate Professorship from the Turkish Interuniversity Council in 2019.\n\nHe was Lecturer at Burdur Vocational School in Suleyman Demirel University (1993-2000, Burdur / Turkey), Software Engineer (2000-2002, Izmir / Turkey), Research Assistant in Bulent Ecevit University (2002-2003, Zonguldak / Turkey), Research Assistant in Dokuz Eylul University (2003-2010, Izmir / Turkey), Assistant Professor at the Department of Electrical and Electronics Engineering in Bulent Ecevit University (2010-2012, Zonguldak / Turkey), Assistant Professor at the Department of Biomedical Engineering in Izmir Katip Celebi University (2012-2019, Izmir / Turkey). He is an Associate Professor at the Department of Biomedical Engineering at Izmir Katip Celebi University, Izmir / Turkey, since 2019. In addition to academics, he has also founded Islerya Medical and Information Technologies Company, Izmir / Turkey, since 2017.\n\nHis main research interests cover biomedical signal processing, pattern recognition, medical device design, programming, and embedded systems. He has many scientific papers and participated in several projects in these study fields. He was an IEEE Student Member (2009-2011) and IEEE Member (2011-2014) and has been IEEE Senior Member since 2014.",institutionString:null,institution:{name:"Izmir Kâtip Çelebi University",country:{name:"Turkey"}}},{id:"339677",title:"Dr.",name:"Mrinmoy",middleName:null,surname:"Roy",slug:"mrinmoy-roy",fullName:"Mrinmoy Roy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/339677/images/16768_n.jpg",biography:"An accomplished Sales & Marketing professional with 12 years of cross-functional experience in well-known organisations such as CIPLA, LUPIN, GLENMARK, ASTRAZENECA across different segment of Sales & Marketing, International Business, Institutional Business, Product Management, Strategic Marketing of HIV, Oncology, Derma, Respiratory, Anti-Diabetic, Nutraceutical & Stomatological Product Portfolio and Generic as well as Chronic Critical Care Portfolio. A First Class MBA in International Business & Strategic Marketing, B.Pharm, D.Pharm, Google Certified Digital Marketing Professional. Qualified PhD Candidate in Operations and Management with special focus on Artificial Intelligence and Machine Learning adoption, analysis and use in Healthcare, Hospital & Pharma Domain. Seasoned with diverse therapy area of Pharmaceutical Sales & Marketing ranging from generating revenue through generating prescriptions, launching new products, and making them big brands with continuous strategy execution at the Physician and Patients level. Moved from Sales to Marketing and Business Development for 3.5 years in South East Asian Market operating from Manila, Philippines. Came back to India and handled and developed Brands such as Gluconorm, Lupisulin, Supracal, Absolut Woman, Hemozink, Fabiflu (For COVID 19), and many more. In my previous assignment I used to develop and execute strategies on Sales & Marketing, Commercialization & Business Development for Institution and Corporate Hospital Business portfolio of Oncology Therapy Area for AstraZeneca Pharma India Ltd. Being a Research Scholar and Student of ‘Operations Research & Management: Artificial Intelligence’ I published several pioneer research papers and book chapters on the same in Internationally reputed journals and Books indexed in Scopus, Springer and Ei Compendex, Google Scholar etc. Currently, I am launching PGDM Pharmaceutical Management Program in IIHMR Bangalore and spearheading the course curriculum and structure of the same. I am interested in Collaboration for Healthcare Innovation, Pharma AI Innovation, Future trend in Marketing and Management with incubation on Healthcare, Healthcare IT startups, AI-ML Modelling and Healthcare Algorithm based training module development. I am also an affiliated member of the Institute of Management Consultant of India, looking forward to Healthcare, Healthcare IT and Innovation, Pharma and Hospital Management Consulting works.",institutionString:null,institution:{name:"Lovely Professional University",country:{name:"India"}}},{id:"310576",title:"Prof.",name:"Erick Giovani",middleName:null,surname:"Sperandio Nascimento",slug:"erick-giovani-sperandio-nascimento",fullName:"Erick Giovani Sperandio Nascimento",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y00002pDKxDQAW/ProfilePicture%202022-06-20%2019%3A57%3A24.788",biography:"Prof. Erick Sperandio is the Lead Researcher and professor of Artificial Intelligence (AI) at SENAI CIMATEC, Bahia, Brazil, also working with Computational Modeling (CM) and HPC. He holds a PhD in Environmental Engineering in the area of Atmospheric Computational Modeling, a Master in Informatics in the field of Computational Intelligence and Graduated in Computer Science from UFES. He currently coordinates, leads and participates in R&D projects in the areas of AI, computational modeling and supercomputing applied to different areas such as Oil and Gas, Health, Advanced Manufacturing, Renewable Energies and Atmospheric Sciences, advising undergraduate, master's and doctoral students. He is the Lead Researcher at SENAI CIMATEC's Reference Center on Artificial Intelligence. In addition, he is a Certified Instructor and University Ambassador of the NVIDIA Deep Learning Institute (DLI) in the areas of Deep Learning, Computer Vision, Natural Language Processing and Recommender Systems, and Principal Investigator of the NVIDIA/CIMATEC AI Joint Lab, the first in Latin America within the NVIDIA AI Technology Center (NVAITC) worldwide program. He also works as a researcher at the Supercomputing Center for Industrial Innovation (CS2i) and at the SENAI Institute of Innovation for Automation (ISI Automação), both from SENAI CIMATEC. He is a member and vice-coordinator of the Basic Board of Scientific-Technological Advice and Evaluation, in the area of Innovation, of the Foundation for Research Support of the State of Bahia (FAPESB). He serves as Technology Transfer Coordinator and one of the Principal Investigators at the National Applied Research Center in Artificial Intelligence (CPA-IA) of SENAI CIMATEC, focusing on Industry, being one of the six CPA-IA in Brazil approved by MCTI / FAPESP / CGI.br. He also participates as one of the representatives of Brazil in the BRICS Innovation Collaboration Working Group on HPC, ICT and AI. He is the coordinator of the Work Group of the Axis 5 - Workforce and Training - of the Brazilian Strategy for Artificial Intelligence (EBIA), and member of the MCTI/EMBRAPII AI Innovation Network Training Committee. He is the coordinator, by SENAI CIMATEC, of the Artificial Intelligence Reference Network of the State of Bahia (REDE BAH.IA). He leads the working group of experts representing Brazil in the Global Partnership on Artificial Intelligence (GPAI), on the theme \"AI and the Pandemic Response\".",institutionString:"Manufacturing and Technology Integrated Campus – SENAI CIMATEC",institution:null},{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/1063/images/system/1063.png",biography:"Prof. Dr. Constantin Voloşencu graduated as an engineer from\nPolitehnica University of Timișoara, Romania, where he also\nobtained a doctorate degree. He is currently a full professor in\nthe Department of Automation and Applied Informatics at the\nsame university. Dr. Voloşencu is the author of ten books, seven\nbook chapters, and more than 160 papers published in journals\nand conference proceedings. He has also edited twelve books and\nhas twenty-seven patents to his name. He is a manager of research grants, editor in\nchief and member of international journal editorial boards, a former plenary speaker, a member of scientific committees, and chair at international conferences. His\nresearch is in the fields of control systems, control of electric drives, fuzzy control\nsystems, neural network applications, fault detection and diagnosis, sensor network\napplications, monitoring of distributed parameter systems, and power ultrasound\napplications. He has developed automation equipment for machine tools, spooling\nmachines, high-power ultrasound processes, and more.",institutionString:"Polytechnic University of Timişoara",institution:{name:"Polytechnic University of Timişoara",country:{name:"Romania"}}},{id:"221364",title:"Dr.",name:"Eneko",middleName:null,surname:"Osaba",slug:"eneko-osaba",fullName:"Eneko Osaba",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/221364/images/system/221364.jpg",biography:"Dr. Eneko Osaba works at TECNALIA as a senior researcher. He obtained his Ph.D. in Artificial Intelligence in 2015. He has participated in more than twenty-five local and European research projects, and in the publication of more than 130 papers. He has performed several stays at universities in the United Kingdom, Italy, and Malta. Dr. Osaba has served as a program committee member in more than forty international conferences and participated in organizing activities in more than ten international conferences. He is a member of the editorial board of the International Journal of Artificial Intelligence, Data in Brief, and Journal of Advanced Transportation. He is also a guest editor for the Journal of Computational Science, Neurocomputing, Swarm, and Evolutionary Computation and IEEE ITS Magazine.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"275829",title:"Dr.",name:"Esther",middleName:null,surname:"Villar-Rodriguez",slug:"esther-villar-rodriguez",fullName:"Esther Villar-Rodriguez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/275829/images/system/275829.jpg",biography:"Dr. Esther Villar obtained a Ph.D. in Information and Communication Technologies from the University of Alcalá, Spain, in 2015. She obtained a degree in Computer Science from the University of Deusto, Spain, in 2010, and an MSc in Computer Languages and Systems from the National University of Distance Education, Spain, in 2012. Her areas of interest and knowledge include natural language processing (NLP), detection of impersonation in social networks, semantic web, and machine learning. Dr. Esther Villar made several contributions at conferences and publishing in various journals in those fields. Currently, she is working within the OPTIMA (Optimization Modeling & Analytics) business of TECNALIA’s ICT Division as a data scientist in projects related to the prediction and optimization of management and industrial processes (resource planning, energy efficiency, etc).",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"49813",title:"Dr.",name:"Javier",middleName:null,surname:"Del Ser",slug:"javier-del-ser",fullName:"Javier Del Ser",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49813/images/system/49813.png",biography:"Prof. Dr. Javier Del Ser received his first PhD in Telecommunication Engineering (Cum Laude) from the University of Navarra, Spain, in 2006, and a second PhD in Computational Intelligence (Summa Cum Laude) from the University of Alcala, Spain, in 2013. He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. He is a Senior Member of the IEEE, and a recipient of the Biscay Talent prize for his academic career.",institutionString:"Tecnalia Research & Innovation",institution:null},{id:"278948",title:"Dr.",name:"Carlos Pedro",middleName:null,surname:"Gonçalves",slug:"carlos-pedro-goncalves",fullName:"Carlos Pedro Gonçalves",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRcmyQAC/Profile_Picture_1564224512145",biography:'Carlos Pedro Gonçalves (PhD) is an Associate Professor at Lusophone University of Humanities and Technologies and a researcher on Complexity Sciences, Quantum Technologies, Artificial Intelligence, Strategic Studies, Studies in Intelligence and Security, FinTech and Financial Risk Modeling. He is also a progammer with programming experience in:\n\nA) Quantum Computing using Qiskit Python module and IBM Quantum Experience Platform, with software developed on the simulation of Quantum Artificial Neural Networks and Quantum Cybersecurity;\n\nB) Artificial Intelligence and Machine learning programming in Python;\n\nC) Artificial Intelligence, Multiagent Systems Modeling and System Dynamics Modeling in Netlogo, with models developed in the areas of Chaos Theory, Econophysics, Artificial Intelligence, Classical and Quantum Complex Systems Science, with the Econophysics models having been cited worldwide and incorporated in PhD programs by different Universities.\n\nReceived an Arctic Code Vault Contributor status by GitHub, due to having developed open source software preserved in the \\"Arctic Code Vault\\" for future generations (https://archiveprogram.github.com/arctic-vault/), with the Strategy Analyzer A.I. module for decision making support (based on his PhD thesis, used in his Classes on Decision Making and in Strategic Intelligence Consulting Activities) and QNeural Python Quantum Neural Network simulator also preserved in the \\"Arctic Code Vault\\", for access to these software modules see: https://github.com/cpgoncalves. He is also a peer reviewer with outsanding review status from Elsevier journals, including Physica A, Neurocomputing and Engineering Applications of Artificial Intelligence. Science CV available at: https://www.cienciavitae.pt//pt/8E1C-A8B3-78C5 and ORCID: https://orcid.org/0000-0002-0298-3974',institutionString:"University of Lisbon",institution:{name:"Universidade Lusófona",country:{name:"Portugal"}}},{id:"241400",title:"Prof.",name:"Mohammed",middleName:null,surname:"Bsiss",slug:"mohammed-bsiss",fullName:"Mohammed Bsiss",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241400/images/8062_n.jpg",biography:null,institutionString:null,institution:null},{id:"276128",title:"Dr.",name:"Hira",middleName:null,surname:"Fatima",slug:"hira-fatima",fullName:"Hira Fatima",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/276128/images/14420_n.jpg",biography:"Dr. Hira Fatima\nAssistant Professor\nDepartment of Mathematics\nInstitute of Applied Science\nMangalayatan University, Aligarh\nMobile: no : 8532041179\nhirafatima2014@gmal.com\n\nDr. Hira Fatima has received his Ph.D. degree in pure Mathematics from Aligarh Muslim University, Aligarh India. Currently working as an Assistant Professor in the Department of Mathematics, Institute of Applied Science, Mangalayatan University, Aligarh. She taught so many courses of Mathematics of UG and PG level. Her research Area of Expertise is Functional Analysis & Sequence Spaces. She has been working on Ideal Convergence of double sequence. She has published 17 research papers in National and International Journals including Cogent Mathematics, Filomat, Journal of Intelligent and Fuzzy Systems, Advances in Difference Equations, Journal of Mathematical Analysis, Journal of Mathematical & Computer Science etc. She has also reviewed few research papers for the and international journals. She is a member of Indian Mathematical Society.",institutionString:null,institution:null},{id:"414880",title:"Dr.",name:"Maryam",middleName:null,surname:"Vatankhah",slug:"maryam-vatankhah",fullName:"Maryam Vatankhah",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Borough of Manhattan Community College",country:{name:"United States of America"}}},{id:"414879",title:"Prof.",name:"Mohammad-Reza",middleName:null,surname:"Akbarzadeh-Totonchi",slug:"mohammad-reza-akbarzadeh-totonchi",fullName:"Mohammad-Reza Akbarzadeh-Totonchi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Ferdowsi University of Mashhad",country:{name:"Iran"}}},{id:"414878",title:"Prof.",name:"Reza",middleName:null,surname:"Fazel-Rezai",slug:"reza-fazel-rezai",fullName:"Reza Fazel-Rezai",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"American Public University System",country:{name:"United States of America"}}},{id:"302698",title:"Dr.",name:"Yao",middleName:null,surname:"Shan",slug:"yao-shan",fullName:"Yao Shan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Dalian University of Technology",country:{name:"China"}}},{id:"125911",title:"Prof.",name:"Jia-Ching",middleName:null,surname:"Wang",slug:"jia-ching-wang",fullName:"Jia-Ching Wang",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Central University",country:{name:"Taiwan"}}},{id:"357085",title:"Mr.",name:"P. Mohan",middleName:null,surname:"Anand",slug:"p.-mohan-anand",fullName:"P. Mohan Anand",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Indian Institute of Technology Kanpur",country:{name:"India"}}},{id:"356696",title:"Ph.D. Student",name:"P.V.",middleName:null,surname:"Sai Charan",slug:"p.v.-sai-charan",fullName:"P.V. Sai Charan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Indian Institute of Technology Kanpur",country:{name:"India"}}},{id:"357086",title:"Prof.",name:"Sandeep K.",middleName:null,surname:"Shukla",slug:"sandeep-k.-shukla",fullName:"Sandeep K. Shukla",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Indian Institute of Technology Kanpur",country:{name:"India"}}},{id:"356823",title:"MSc.",name:"Seonghee",middleName:null,surname:"Min",slug:"seonghee-min",fullName:"Seonghee Min",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Daegu University",country:{name:"Korea, South"}}},{id:"353307",title:"Prof.",name:"Yoosoo",middleName:null,surname:"Oh",slug:"yoosoo-oh",fullName:"Yoosoo Oh",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:"Yoosoo Oh received his Bachelor's degree in the Department of Electronics and Engineering from Kyungpook National University in 2002. He obtained his Master’s degree in the Department of Information and Communications from Gwangju Institute of Science and Technology (GIST) in 2003. In 2010, he received his Ph.D. degree in the School of Information and Mechatronics from GIST. In the meantime, he was an executed team leader at Culture Technology Institute, GIST, 2010-2012. In 2011, he worked at Lancaster University, the UK as a visiting scholar. In September 2012, he joined Daegu University, where he is currently an associate professor in the School of ICT Conver, Daegu University. Also, he served as the Board of Directors of KSIIS since 2019, and HCI Korea since 2016. From 2017~2019, he worked as a center director of the Mixed Reality Convergence Research Center at Daegu University. From 2015-2017, He worked as a director in the Enterprise Supporting Office of LINC Project Group, Daegu University. His research interests include Activity Fusion & Reasoning, Machine Learning, Context-aware Middleware, Human-Computer Interaction, etc.",institutionString:null,institution:{name:"Daegu Gyeongbuk Institute of Science and Technology",country:{name:"Korea, South"}}},{id:"262719",title:"Dr.",name:"Esma",middleName:null,surname:"Ergüner Özkoç",slug:"esma-erguner-ozkoc",fullName:"Esma Ergüner Özkoç",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Başkent University",country:{name:"Turkey"}}},{id:"346530",title:"Dr.",name:"Ibrahim",middleName:null,surname:"Kaya",slug:"ibrahim-kaya",fullName:"Ibrahim Kaya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Izmir Kâtip Çelebi University",country:{name:"Turkey"}}},{id:"419199",title:"Dr.",name:"Qun",middleName:null,surname:"Yang",slug:"qun-yang",fullName:"Qun Yang",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Auckland",country:{name:"New Zealand"}}}]}},subseries:{item:{id:"15",type:"subseries",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11411,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. 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