Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\n
We wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\n
Throughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\n
We wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
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Based on the research in this area in recent decades, "Contemporary Approach to Dental Caries" contained the caries in general, the diagnosis of caries, caries control and prevention, the medical treatment of caries, dental caries in children and others such as secondary caries. This book provides the reader with a guide of progress on the study of dental caries. The book will appeal to dental students, educators, hygienists, therapists and dentists who wish to update their knowledge. 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1. Introduction
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Bitcoin is based on three technologies: the Internet, encryption methods, and the new blockchain technology. Unlike these technologies, the Bitcoin revolution was both a technological revolution and a monetary one. It completely changed the monetary world, and it seems that its invention opened a Pandora box, whose effect cannot be underestimated or predicted. Since its inception in 2009, the Bitcoin project had many opponents, and like any successful project, their number increases gradually.
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It is not very surprising to hear criticism from the industries and organization, which feel intimidated by the new invention. One would expect to find criticism from leaders in the banking industries, the insurance, and investment industries and, of course, from politicians. It is not even surprising to find criticism in the academic world, since, after all, one of the main tasks of the academic world is to instill past knowledge into the future generation and to be skeptical of new ideas.
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On the other hand, since Bitcoin is a decentralized technology, it was warmly adopted by anarchist organizations worldwide [1, 2, 3], but for similar reasons, it was attacked by many others [4, 5, 6, 7, 8, 9]. Some attacked the Bitcoin from the fear of shaking the current centers of powers, but most attacked it out of ignorance. Strangely enough, even in the libertarian community, which in general embraced the new currency, there are some that used allegedly Austrian economics arguments to debunk the foundation of the Bitcoin economy [10, 11, 12, 13, 14].
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In general, we encounter two strategies to attack Bitcoin: (1) presenting multiple minor or even clearly erroneous arguments. Consequently, the arguments keep reappearing, despite the fact that they are constantly refuted. And (2) using fundamental economic laws to allegedly demonstrate that Bitcoin does not possess the essential properties of money.
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The object of the chapter is twofold: (1) to present and refute all the main arguments in a single chapter and (2) to utilize these arguments to reinvestigate the origin of the source of money in general and cryptocurrency in particular.
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So, let us begin with the simple arguments:
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2. Is Bitcoin a Ponzi scheme?
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The most common criticism against Bitcoin is that Bitcoin is actually a Ponzi scheme [7, 10]. Clearly, there is no resemblance between the two. A Ponzi scheme is a fraudulent investment operation. The investors are made to believe that they gain from the investment operation, while in fact, the money comes from new investment, that is, a Ponzi scheme is a pyramid fraud.
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While some cryptocurrencies or tokens do seem to be a Ponzi scheme, Bitcoin is definitely not. Everything about Bitcoin: its algorithm, its network, and its development projects are completely transparent. The network, the mining process, and the entire project are all decentralized. There are no managers, no organizers, and no control. Therefore, there could be no fraud.
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Bitcoin does not even have a pyramid structure. An investor in Bitcoin can make a profit by selling it at a higher price, just like in any other trade. Unlike pyramid structures, the owner of Bitcoins does not have to convince multiple people to invest in order to make a profit.
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It is true that in both cases, the first investors gain more than the last ones, and that their profit rises with the number of traders. However, by the law of demand, it is clear that the price rises with the increase in demand, that is, the price increases with the number of buyers. This is valid for any commodity, and Bitcoin is no exception. This is definitely not a pyramid structure’s fingerprint. Moreover, the whole network structure is different. A pyramid is a centralized structure, where there is a clear asymmetry between investors and all profits eventually dissipate toward the founders of the pyramid (this is a “top-down” business model). Bitcoin is a decentralized network, where all the Bitcoins’ owners have the same status. Moreover, the founders of a crypto network may not even own a share in this network, or they can sell their share, if they have one (like Charlie Lee, the founder of the Litecoin network, who recently sold all his Litecoins).
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3. Bitcoin is a bubble
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Another common criticism is that Bitcoin and the other cryptocurrencies are a bubble [4, 6, 8]. This claim is not a very informative one. What does it mean? Does it mean that the Bitcoin price is too high? In a free market, the price is always right. If there is something “wrong” with the price, then it means that the market is not really free. When there is a housing bubble, it does not mean that there is something wrong with the houses, or that the sellers are greedier than they usually are, but it does mean that the government manipulates the interest rate and subsidizes bad mortgages, etc.
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Therefore, any “bubble” claim is actually not a criticism against Bitcoin, but a claim against something external to its network—probably against governments. If everyone buys cryptocurrencies, it is probably because the public has no other investment channels. The banking interest is practically zero; the stock market is too high after 10 consecutive years of rising prices; and the housing market is recovering from the latest collapse. The fact that Bitcoin is in a state of a bubble, whatever that means, cannot be used as evidence to the argument that Bitcoin is worthless.
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As Ludwig Wittgenstein wrote, “For whenever we test anything, we are already presupposing something that is not tested.” Similarly, when one believes the price of Bitcoin is too high, he presupposes that Bitcoin has some value.
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4. Bitcoin yields no return
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Another repeating argument is that Bitcoin is not a real asset in the sense that it does not yield any return. Unlike stocks or real estates, which yield dividends and rents, Bitcoin does not “yield” anything. People purchase Bitcoin only to sell it later.
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But this is a strange argument, since, after all, money never yields return. A one-dollar note does not yield a return. It will be worth 1$ forever. Nevertheless, people “purchase” dollars only to “sell” them later for goods. This is exactly the function of money and the same applies to Bitcoin.
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5. The Bitcoin’s volatility
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One very common attack on Bitcoin is that it must be useless as money (or currency) since it has very high volatility [12, 13].
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Clearly, if an asset’s value is very volatile, then it is less likely to be adopted as a unit of account, which is one of the properties of money. However, it should not considerably affect its prospects to be used as a medium of exchange. Even today, most Bitcoin transactions are quantified in US dollars, that is, in these transactions, Bitcoin is used as a medium of exchange, while the US dollar is used as a unit of account. However, it should be stressed that in these transactions, the dollar takes no role. Bitcoin is currently exploring a new territory, in which it is used as a medium of exchange, but yet to be used as a unit of account (on this discrepancy see Ref. [15]).
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Moreover, the usage of the volatility criterion is useful only in close-to-equilibrium’s markets. In the case of Bitcoin, the price increases exponentially, which is a clear sign of a nonequilibrium scenario. Exponential rise is an indication of a constant amplification process, which cannot occur in the vicinity of equilibria. In this case, it is clear that the volatility will increase exponentially as well. Therefore, there could be two options: (A) the approximately constant amplification process is close to its end, in which case the market will converge to a semiequilibrium state, and the volatility will decrease dramatically. (B) The constant amplification process is going to last for some time, in which case the value of Bitcoin will continue to rise dramatically.
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Therefore, in both cases, the attractiveness of Bitcoin will increase, and in any case, the high volatility in an exponentially growing process cannot be used as an argument for the claim that Bitcoin is worthless. It is only a sign that the crypto market is in its infancy stages.
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In an exponentially growing economy, the volatility should be evaluated in logarithmic scale, and in this scale, the Bitcoins’ volatility actually declines.
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6. The hoarding dilemma
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Another important claim is that Bitcoin is worthless as a medium of exchange because most people, who purchased it, hoard the coins [12, 13]. Since most people regard Bitcoin as a store of value and “Hodl” (the crypto nickname for hold) the coins, how can it be used as a medium of exchange? This claim is often heard even in the crypto community, where the holders are encouraged to exchange their coins with goods, that is, to sell and buy the coins repeatedly (e.g., Ivan Liljeqvist and Rick Falkvinge). However, the two properties of money are tightly linked. A good cannot be a store of value unless it is a medium of exchange and vice versa. How can an object be valuable, without the option of exchanging it for something else? How can something be a medium of exchange, unless it is valuable?
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Moreover, hoarding takes place only when people expect that the coins’ price will rise in the future. In this case, fewer coins are used in circulation and, as a consequence, their price increases. This is the mechanism that persuades the hoarders to part with their coins.
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7. A deflationary economy
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The hoarding dilemma is a very important point because it is related to another criticism: how can Bitcoin be used as a medium of exchange while being a deflationary currency? In a deflationary monetary economy, the argument continues, prices decrease perpetually, and therefore people have no incentive to buy anything, for they know that they will probably get it for less money in the future. In such an economy, consumption decreases, and the economy stagnates.
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There are several problems with this argument. First, there is a problem of definition. Bitcoin is an inflationary currency, not a deflationary one since the number of coins increases gradually. It is true, however, that its rate decreases, and eventually the total number of coins is limited (around 21 million). Consequently, in a progressing economy, which is based on Bitcoin, eventually, the Bitcoin inflation will be lower than the economy’s growth rate. In such an economy, the products’ prices will eventually decrease. This state is wrongly termed “deflationary” [16, 17]. However, and this brings us to the second misconception, there is nothing wrong with rising prices. In fact, the economic sectors, which experience decreasing prices, are the sectors with the highest growth rate. The computer industry belongs to this category. Computer prices perpetually decline for decades, while the industry is growing. Not only that people did not stop from buying computers, but computers’ sales are gradually increasing.
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People have needs, and as economists explain, they have a time preference, that is, they do not like to postpone gratifications [16, 17, 18]. If they need a computer, they will eventually buy it, and decreasing prices is a good incentive to make the purchase. Eventually, they will buy the computer.
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The third misconception is that saving is worse than spending and therefore people should be encouraged to spend their money. In fact, unlike the Keynesian thinking, over consumption is the enemy of economic growth. Clearly, people have to buy to encourage production; however, the economy cannot grow unless there is enough savings and investments. That is, as was explained by Hayek (in “the paradox of savings” [19]), when people save their money, they only postpone their consumption; they do not stop consumption altogether. Saving is a crucial ingredient in any economic growth, and therefore, there is nothing harmful in an economy with rising prices. In fact, at the end of the nineteenth century, when the American economy was based on the gold standard, the US experienced one of its best economic eras during a deflationary period [20, 21].
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Evidence shows that any economy will gain from a “deflationary” currency, such as Bitcoin (or even gold, for that matter). However, if, in the future, it will be clear that there are some benefits to inflationary currency, then there are many other coins, in which inflation is part of their algorithm, for which case there is no upper limit to the number of coins. Let the market decide on the best inflationary/deflationary algorithm.
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8. Bitcoin and the government
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There is a claim that governments may create a competitive coin to Bitcoin, and simultaneously, the governments can outlaw Bitcoin. Indeed, the government can create a token of its own, and it seems that some governments seriously think about such an enterprise [22, 23, 24]. However, it is not clear what would be their motives. If these governments intend to create simply a true decentralized competitor to Bitcoin, then they would face two problems: (1) a government would never be able to compete against the decentralization level of Bitcoin and (2) with a decentralized coin, the government would lose all its benefits of controlling the national currency, that is, by replacing fiat currency with cryptocurrency, the government literally kills the goose that lays golden eggs.
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If the government plans on creating a centralized coin (i.e., government-controlled currency), then it could not rely on the good reputation of decentralized coins. In this case, the government would encounter a great difficulty to sell the coin to the Bitcoin community (see what happens with the new Venezuela’s Petro).
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Governments can confront the problem differently, and it can try to ban Bitcoin. This is evidently possible de jure but not de facto. The more the government manipulates the currency, the more the people need cryptocurrencies (see, e.g., the case of Zimbabwe, India, and Venezuela).
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9. Technology-based money
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There is a good question regarding Bitcoin’s longevity. Bitcoin, the claim argues, is a technological invention. In principle, there is no reason that it would not be defeated by competing technologies. Unlike gold, which would exist forever, Bitcoin is a technology that changes in time. This is an interesting argument; however, in fact, this argument only emphasizes the similarities between gold and Bitcoin. Gold is here to stay, but so does Bitcoin. Actually, due to its decentralization, it would be extremely difficult to eliminate the entire Bitcoin blockchain. To achieve that, every copy of the blockchain should be erased. The chances of that are extremely low. Clearly, the value of the blockchain can decline substantially, but this is equivalent to a decline in the price of gold due to a lack of (technological or financial) interest. Therefore, gold is not better money than Bitcoin due to the fact that “while Bitcoin can be overthrown by competitive technologies, gold will exist forever.” In fact, they both will probably survive for a very long time, and both may lose their value due to competitive technologies, because, in its essence, gold is also a monetary technology.
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Having said that, it must be emphasized that a replacement of a monetary technology is a very challenging task. Financial markets are very conservative.
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Gold has no clear chemical advantage over (for example) platinum, palladium, or iridium, and the main reason that gold is preferred over these precious metals is its early adoption as a medium of exchange (possibly due to its unique yellowish color). It may be instructive to note that there have been several attempts in the history to replace gold with other metals (iron in Sparta, copper in Rome, and even silver in the US); however, these attempts did not affect the gold’s hegemony worldwide.
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The same thing applies to Bitcoin. Bitcoin enjoys the network effect due to its early adoption. The gold’s unique color and its plasticity made it relatively resistant to counterfeiting. However, gold counterfeiting is still possible (e.g., by covering tungsten with a layer of gold, because tungsten and gold have almost the same density), while Bitcoin cannot be counterfeited.
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10. Genuine scarcity
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This brings us to a well-known argument, that says that Bitcoin, like any other digital asset, is not scarce, and therefore can be repeatedly reproduced. The knowledgeable Bitcoin’s opponent, which uses this argument, does not mean that the number of Bitcoins can be increased ad infinitum. He means that the algorithm can be copied and an infinite amount of rival crypto networks can be created. In fact, during the writing of these lines, there are literally thousands of cryptocurrencies networks: Bitcoins, Ethereum, Ripple, Bitcoin Cash, Cardano, Litecoin, Stellar, NEO, EOS, and IOTA to mention only the first 10 within the highest market cap list. Moreover, each one of these coins can be forked to other coins. The original Bitcoin network was forked many times to Bitcoin cash, Bitcoin gold, Bitcoin diamond, Bitcoin segwit2x, etc.
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The argument is, therefore, that digital assets, like cryptocurrencies, can be even worse than fiat currencies, for while fiat currencies’ inflation is regulated by central banks, and the number of cryptocurrencies can be inflated uncontrollably. However, Bitcoin is not only an algorithm. Indeed, the cost of copying the algorithm is negligible. But Bitcoin is also a very secure network. Every new Bitcoin-clone does not benefit from the same level of security. The more computational power is invested in the network; the more secure the network is, and the more people would find it safe to invest their money in it.
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Bitcoin may lose its hegemony in the crypto sphere; however, as was explained above, it would be very difficult for new networks to pose a real threat to Bitcoin due to its proven high security and reliability.
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11. Bitcoin transactions are too slow and too expensive
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Recently, the Bitcoin adversaries took advantage of the heavy load on the Bitcoin network, which caused slow and high fee transactions, to claim that the Bitcoin does not deliver its promises—Bitcoin transactions are too slow and too expensive. Soon, they predict, the Bitcoin network will be so cumbersome, that transactions will become unfeasible, and the Bitcoin project will be abandoned. This is indeed a problem. But this is a technological problem and not a fundamental one. It may explain why the Bitcoin market dominance declines, but it can never be used to explain why Bitcoin should be worthless. Clearly, the Bitcoin developers are aware of these problems and work constantly to mitigate the harmful effects of the network load.
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Several technological improvements have been suggested and implemented (SegWit, lighting network, atomic swap, and even raising block size in a forked versions of Bitcoin).
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Moreover, there are countless other currencies, whose transactions are much quicker and cheaper, and yet their value is considerably lower than the value of the Bitcoin network. Despite the fact that the technology is yet in its infancy stages, and there are still numerous technological challenges, the value of Bitcoin keeps on growing.
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Therefore, these facts should be an argument for Bitcoin and not against it, because these problems show that the need for reliable decentralized currency in the modern markets is so high, that people keep purchasing it despite the high transaction costs (and despite the fact that there are low cost but less proven alternatives).
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12. Currencies backed by nothing
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A very popular argument against cryptocurrencies is that they are backed by nothing: “They are neither backed by gold nor are they backed by governments.”
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Clearly, these are two different arguments. President Nixon, in 1971, was responsible to complete the monetary experiment that began at 1944 with the Bretton Woods system. Since then, there is not a single fiat currency in the entire globe, which is backed by gold or by any other commodity. Hence, a commodity backup is not a crucial ingredient in the making of money. As for the second argument, what does it mean that the currency is backed by the government?
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Clearly, if the government backs its currency by forbidding the usage of other currencies (in its geographical territory), then it enforces a certain minimum value for the currency. However, not all governments can or do that. In most countries, the population can make economic transactions with many currencies. Most governments back their currencies by enforcing tax payment with them. Similarly, the governments pay their employees with the national currency. However, these conducts are equivalent to the presence of a rich man in a market, who declares that any economic transaction with him can take place only with a certain currency. As richer this man is, the higher will be the value of this currency. Clearly, a government is equivalent to a very rich man, but the differences are quantitative rather than qualitative ones.
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One of the most instructive examples in this regard is the Swiss dinars in northern Iraq during the gulf war [25]. This is a very interesting example, which vividly illustrates the fact that paper money can be used as a medium of exchange, despite the fact that it is backed neither by any commodity nor by any government.
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13. Dependence on the current monetary system
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An argument against Bitcoin, which was very common in its early years, is that Bitcoin is not a real medium of exchange because most traders, which accept Bitcoin, convert them to fiat currency almost immediately after the transaction.
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Nowadays, this argument is heard less since many sellers prefer Bitcoin over fiat money. They prefer spending their fiat money and receive and keep their cryptos. Moreover, nowadays many employees are paid in cryptocurrency.
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However, it is important to stress that whether the users of Bitcoin prefer to make an additional transaction after selling a product, that is, to convert the crypto to fiat, is irrelevant to the validity of Bitcoin as a medium of exchange. First, there is no praxeological difference between the exchange of Bitcoin with fiat and the exchange of Bitcoin with other goods. If a seller prefers to convert Bitcoin into fiat currencies, it only means that he had decided to use Bitcoin as a medium of exchange to purchase the fiat currencies. Moreover, one should not ignore the fact that the main reason that sellers prefer to convert their cryptos back into fiat is due to government regulations (mainly taxation) and has nothing to do with the fundamental monetary properties of Bitcoin.
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14. Bitcoin and economic calculations
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Some Austrian economists used the volatility problem and the last argument to claim that Bitcoin cannot be used for economic calculations. Since economic calculations are essential to any modern economy [16], it is futile, according to them, to replace the current fiat currency with Bitcoin. However, economic calculations can be made with any commodity. When a businessman has four bottles of wines, and he needs to choose between two production alternatives: one alternative that will eventually yield three additional bottles and a second one that will eventually yield five bottles, he will choose the latter. The same thing applies to Bitcoin. Crypto traders already practice this kind of economic calculations using Bitcoin.
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However, volatility is indeed a problem (mainly in intra-temporal calculations, i.e., interest rates), which prevents wide adoption. Nevertheless, as was explained above, the volatility gradually declines, and it is one of the infancy problems of Bitcoin, and it is not a fundamental one.
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15. Bitcoin and the division of labor
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Division of labor cannot exist in a nonmonetary economy. The presence of money drives people to specialize and increases their productivity beyond their personal needs. They can trade the surplus of their production in order to pursue higher gratifications (for the analysis of production in the presence of specialization, see Ref. [26]).
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Therefore, any adoption of Bitcoin as a medium of exchange should be accompanied by an upgrade of the division of labor. Is there any evidence for this?
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The problem is that it is almost impossible to attribute scientifically a specific improvement in the division of labor to a specific cause. However, it is clear that if a person prefers using Bitcoin than other currency, then he must have found it useful and more efficient for him. Therefore, this individual can spend the surplus time in further specialization.
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Consequently, in a free market, any unregulated usage of Bitcoin (or anything else for that matter) is a circumstantial evidence for upgrading the division of labor.
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16. Bitcoin and property rights
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Property rights are subtle issues. There is a fundamental claim that intangible objects, like digital assets or ideas, cannot be owned. The claim is based on the presumption that property rights and private ownership are essential to manage scarce resources in the real world. Thus, according to this view, only scarce resources (like, land, houses, gold, etc.) can be owned, while resources that are not scarce (like, ideas, patents, text, digital pictures, etc.) and that can be easily reproduced cannot be owned [27]. Bitcoin is a chimera, in that regard, since it is both digital, that is, intangible, and scarce. In fact, the essence of the blockchain technology is the creation of scarce digital assets. That is, the blockchain creates artificial scarcity.
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Therefore, despite the complex philosophical issue, I believe there is a consensus that Bitcoins can be owned, and property rights can and should be applied to it.
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There is a claim, however, that Bitcoin advocates ignore traditional property rights, contracts, and traditional legal systems, which were developed and refined for millennia [12].
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It is true that currently, it is easier to evade law enforcement using cryptocurrencies than using most bank transactions. The facts that there is nothing tangible in the Bitcoin network and that digital transactions can take place without the regulated banking system complicate law enforcement. However, on the one hand, it can be regarded as a technical difficulty, which may be solved using artificial intelligence technologies, and on the other hand, one may argue that these properties of the Bitcoin network only strengthen property rights, because they prevent government confiscation of private property (private money).
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Not only aren’t crypto networks against contracts, but also smart contracts are an integral part of these networks. The most well-known is the Ethereum network, but there are many more cryptocurrencies with this property (like Neo, EOS, Cardano, etc.), and even the Bitcoin network can support smart contracts (Mastercoin, Rootstock, Particl, etc.).
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Therefore, the blockchain technology eliminates the need for (external) law enforcement in some cases, because the contracts are enforced within the blockchain itself.
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In general, cryptocurrencies strengthen private property and property rights. They do not weaken them.
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17. Bitcoin and crime
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Some politicians and economists believe that Bitcoin and other cryptocurrencies have no value to society since most of their users are outlaws and criminals [28].
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For one thing, one has to make a distinction between the different cryptocurrencies. Most of the criminal activity was transferred from the Bitcoin network to the more private cryptos (such as Monero, Zcash, Verge, etc.) since transactions in the Bitcoin network can be traced.
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Moreover, most of the illegal trade that takes place on the Internet belongs to the category of victimless crimes (like drugs, gambling, and tax evasion), whose prohibition is disputed.
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In any case, the illegal activities that take place on the network only emphasize the fact that the crypto networks are valuable for at least some of the people, and in a market economy, when a commodity is valuable for some of the people, then it is valuable to the entire economy.
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18. Bitcoin and egalitarianism
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There is a claim that a Bitcoin-based economy would increase wealth inequality. This argument is based on the fact that most of the Bitcoin wealth is concentrated in a minuscule amount of Bitcoin addresses [29]. But clearly, wallets and addresses are not persons. Almost every user holds several wallets, and a wallet can and does generate multiple addresses mainly for privacy reasons.
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This argument suffers from an additional fallacy: the distribution of money in a population does not determine the distribution of wealth. Quite the contrary, the distribution of wealth determines the distribution of money. In a free economy, people are paid for creating wealth. Since Bitcoin economy has a higher resemblance to a free economy than our current fiat economy, it seems that in a Bitcoin-based economy, the money distribution will be fairer than the current one.
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19. The value of Bitcoin
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There is a claim that Bitcoin is worthless, because it answers no real need and solves no real problem. This claim can easily be refuted.
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Bitcoin is a global, decentralized, highly liquid, and pseudo-anonymous asset. Therefore, in any transaction, which requires all these properties, the benefits of using Bitcoin over other currencies are clear. Moreover, that is exactly the reason that most people do not appreciate these properties. First, most people are unaware of the damage caused by centralized monetary systems. Second, only rarely do they perform international financial transactions in large volumes. Third, most people are against anonymous transactions.
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However, the benefits of Bitcoin are widely recognized in the following cases:
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(1) Where the centralized monetary system completely collapses (e.g., Venezuela and Zimbabwe). (2) Where the government confiscates its own citizen’s assets (e.g., Cyprus and Saudi Arabia). (3) Among populations, which are excluded from the financial and banking systems (e.g., bankrupted citizens and minors). (4) Among outcasted populations (e.g., drug users and gamblers). (5) Among people who are keener on their privacy (e.g., tax evaders and porn users). (6) Among frequent travelers/flyers.
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In general, it is clear that the Bitcoin technology has a clear value wherever censorship-resistance is required. Money is one example, social media is another (e.g., Steem, LBRY, Memo).
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As was mentioned above, in a market economy, when an asset is valuable to some people, then it is valuable to the entire economy. Consequently, people who do not belong to any of these populations can still regard Bitcoin as a safe haven for their money.
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However, the fact that Bitcoin is valuable only increases the mystery as for the origin of its value. In the previous sections, we have presented the problems in arguments, which claim that Bitcoin should be worthless. Before we present the last argument, which will lead us to the origin of the Bitcoin’s value, it is instructive to discuss incorrect explanations, from which we will learn what cannot explain the origin of the value of Bitcoin.
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20. Backed by energy
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It is repeatedly mentioned by crypto advocates that Bitcoin is backed by proof-of-work, or, that it is backed by energy or by the mining’s electricity.
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In particular, such an explanation was used by John McAfee to justify his prediction of the Bitcoin price at the end of 2020 [30]. The argument goes like that: currently, it costs several million dollars to mine 1800 BTC (the current daily yield). Within few decades, the mining rate will decrease substantially, while there is no reason to assume that the cost will decline (more plausible that it will rise). Therefore, one may conclude that because Bitcoin’s mining cost will rise, its price must rise as well.
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This is a very common error that is based on the classical economists’ theory of value—the labor theory of value. This theory, which was developed by Smith, Ricardo and their followers (including Marx), was based on the premises that the labor is the source of value. This theory helped them to explain the water-diamond paradox, namely, why the value of diamonds is higher than the value of water, while clearly water is much more useful than diamonds. The classical economists would reply that it costs more to mine and to shape diamonds than to pump water from a nearby well. The subjectivist schools of economics, in general, and the Austrian school, in particular, would strongly disagree. Bohm-Bawerk, the well-known economist, would argue that it may be very costly to prepare a mud pie, nevertheless, the mud pie is still worthless. The Austrian economists would argue that the classical economists made it all wrong. It is the price of the product that determines its cost and not the vice-versa. That is, if a producer evaluates that he can sell a product for 1000$, he will be willing to pay production costs, which are lower than 1000$. Clearly, the competition enforces the producer to lower the product’s price until it is close to the product’s cost. However, had he not known that he could sell the product at a price higher than the cost he would not have produced it.
\n
The same thing applies to any product, and mining is not an exception. As long as the market price of gold is higher than the cost of mining, then mining will continue, otherwise, the miners would stop the mining process. That is, the market cost of gold (approximately 1200$/ounce today) determines the maximum cost of mining. In the case of Bitcoin, the mining process cannot stop. In fact, since every 10 min a new block is added to the blockchain, then the algorithm keeps adjusting the mining difficulty to maintain a constant rate of block production. Therefore, the algorithm makes sure that the mining cost would remain below the market price so that mining would never stop.
\n
\n
\n
21. Too costly to mine
\n
A similar reasoning appears in a different argument against Bitcoin: the Bitcoin mining costs are extremely high, and even now, its electricity consumption is equal to that of a small country (like Ireland). Within several years, the costs would be gigantic, and it would be unprofitable to mine additional coins.
\n
Again, this is a complete misunderstanding of the mining process. As was explained above, unlike gold mining, there is no given external cost for mining Bitcoin. The causality between cost and prices works in the opposite direction—Bitcoin prices determine the cost of mining. Therefore, at any given time, the users of the Bitcoin network are the ones who determine the amount of money they are willing to invest in the network security. That is, first, the mining cost cannot increase beyond the amount the users are willing to pay, and second, the electricity cost is not a wasted investment; it is a measure of the network security. The more people trust the Bitcoin network, the more they are willing to invest in it. Consequently, the Bitcoin price increases, and so does, as a byproduct, the mining cost, which measures the network computation power. That is, the more secure the network is, the more trustworthy it becomes in practice via the price mechanism. This is a positive feedback, which strengthens the network. However, there is a limit to the cost of security, which people are willing to pay in any financial transaction. This limit determines the mining cost.
\n
It is interesting that a similar argument was put against the gold standard. Followers of the monetary school of economics argued that unlike fiat money, gold mining is a waste of useful resources, which can be directed to other useful industrial sectors. The answer of the Austrian school was that it is a small price to pay to prevent the government from inflating the amount of money [31]. The Austrian economists have a nice analogy: why so many resources are invested in steel locks? Wouldn’t it be smarter had we replaced them with paper locks and allocate the steel to better uses? This is clearly a rhetorical question. Security is a costly business. We pay for security and safety.
\n
This is an important point. In a stationary economy, or, in the Austrian school terminology, the Evenly Rotating Economy (ERE), the future is already known, and there are neither surprises nor risks. Consequently, there is no need for money. In the ERE, money has no function. People need money only in states of uncertainty. Money helps relieve the sense of uncertainty. However, counterfeiting is a source of concern. Fiat money is susceptible to the whims of the government. Governments can (and do) inflate the money supply indefinitely.
\n
The supply of gold, on the other hand, is regulated by the market, since gold counterfeiting is extremely difficult. Only when the market price exceeds the mining cost, new gold is generated by mining.
\n
The same reasoning applies to Bitcoin. However, there are some very important differences: as was explained above, it is more difficult to counterfeit Bitcoin than gold, let alone fiat currency. Moreover, the ability to counterfeit fiat currency and gold is independent of their value. Therefore, as their value rises, additional counterfeiting attempts are made.
\n
The opposite is true for Bitcoin. The difficulty to attack the Bitcoin network is proportional to the Hash power of the Bitcoin mining; however, the cost of this power is proportional to the price of Bitcoin (since most of the Bitcoins have already been mined). Therefore, unlike fiat money and unlike gold, as the price of Bitcoin rises, it becomes more difficult to attack the network (Bitcoin’s equivalent of counterfeiting).
\n
To summarize this point, the high mining cost is not a waste—it is a security investment.
\n
\n
\n
22. Scarcity and value
\n
Another misconception about the origin of the value of Bitcoin is that unlike fiat money, which is created “out of thin air,” the number of Bitcoins is fixed and cannot be changed, and this inherent scarcity is the source of its value.
\n
First, as was explained above, Bitcoin is also inflationary. In fact, the important characteristic of the decentralized crypto coins is not that coins cannot be created “out of thin air,” but that their creation is fully determined by the well-known protocol and cannot be manipulated by a central entity (i.e., governments). Therefore, the users can take account of the inflation parameters into their future financial contracts. This property of cryptocurrencies is a clear advantage they have over fiat currencies. In fact, this is a major advantage even over commodities backed currencies, such as gold, since the future mining rate of gold is unknown, while cryptocurrencies are created in a predetermined manner.
\n
Second, scarcity, by itself, cannot be the source of value. Using Bohm-Bawerk example, the fact that a certain mud pie cannot be reproduced is, in itself, an insufficient demand to make it valuable. Scarcity is a necessary but insufficient condition for value creation.
\n
\n
\n
23. The regression theorem and the origin of value
\n
It was Karl Helfferich who formulated in 1903 the vicious circle of money [32]. The marginal value theory of Menger, the forefather of the Austrians school, can explain why a handful of diamond worth considerably more than the buckets of water, despite the fact that water is clearly more essential to human existence than diamonds are [33]; however, it could not explain why a seemingly worthless object like pieces of papers can have a high value. In other words, it cannot explain why people would be willing to exchange them with commodities, which have a clear intrinsic value. It was clear that if people, for some reason, attribute value to money, then it would be a logical behavior for the individual to attribute value for money, even if he does not find it useful to himself. However, how did money gain its value in the first place, or, in others word, it is a vicious circle to say that people want money simply because people want money [32].
\n
Mises, apparently, solved this conundrum. He said that people want money today because they anticipate that other people would want it tomorrow since they wanted it yesterday, that is, money has value today because it has value yesterday. By introducing time schedule into the description of the process, Mises circumvented the vicious circle. But he did it with a cost. This logic leads to the unavoidable conclusion that any money had, prior to its use as a medium of exchange, an intrinsic value [34].
\n
Thus, there is an argument that Bitcoin cannot be money since it never had an intrinsic value, that is, while the US fiat dollar is valuable today since it was based on the original value of the gold dollar, which was based for millennia on the currency value of gold, which was based somewhere in the past on the commodity value of gold, they claim that Bitcoin does not have such a chain of events. One cannot find any intrinsic value in the Bitcoin genesis. While gold has an extensive commodity use in its premonetary era, Bitcoin, according to them, had no nonmonetary history and therefore cannot evolve into money.
\n
This claim has several flaws. First, they turn Mises’ argument on its head—Mises used his argument to explain how apparently worthless object can be used as a medium of exchange. Bitcoin is already a medium of exchange, which means that there are only two options, either Mises argument is erroneous or that they are missing something about Bitcoin. In fact, Mises was not entirely accurate and Bitcoin does have a nonmonetary value.
\n
I would like to harness a physical analogy to explain this point—the laser.
\n
When a laser is connected to a power supply, it emits coherent light almost instantaneously. Nowadays, lasers are very common and there is nothing special about this; however, a laser is not a light bulb, the origin of light in a laser can be regarded as a similar mystery. A laser consists of two basic elements: a light amplifier and a resonator, which is actually a feedback mechanism. Hence, a laser is a giant amplifying machine. Using the feedback, the laser keeps on amplifying the light. But wait! Where did the light originally come from? The laser has no element that generates the “original” light (i.e., the primordial photons), it only amplifies it. So where did the light originally come from? Well, actually, this is quite a mystery that nobody really knows. The source can be thermal noise, scattered light, or maybe the zero point energy. While academically it may be an interesting question, it is practically irrelevant to the laser operation. Moreover, it teaches us an important lesson—in the presence of a highly efficient amplifying process, the increase is exponential, and therefore the initial trigger is practically irrelevant. It doesn’t matter whether the process started from a single photon, ten photons or a hundred, the changes in the time till it reaches equilibrium (the time, in which it grows exponentially) is negligible.
\n
The same goes for Bitcoin. It was proven to be a rapidly accelerating phenomenon. In fact, just like the laser intensity or any other phenomenon with an approximately constant rate increase, the value of Bitcoin grew exponentially: within about 4 years it increased by a factor of a million! The technology was proven so successful that the initial value, people attributed to Bitcoin, is unimportant.
\n
The legendary pizza transaction, which allegedly determined its initial market value (in which a couple of pizzas were sold for 10,000 BTC), could be totally different. It could have been sold for 1000 or 100,000 BTCs, and the final outcome would be almost the same and it would be determined by the equilibrium value. In fact, the entire process can start from a whim of a handful of strange geeks (see, for example [35]). That is totally sufficient, exactly like the amplifying process in a laser, which can start, for all we know, from a single photon, which accidentally was present in the laser’s cavity.
\n
In the previous paragraphs, it was explained why one does not have to prove that Bitcoin currently has an intrinsic use value in order to show that its exchange value, that is, its value as a medium of exchange, does not contradict Mises’ regression theorem; nevertheless, Bitcoin had and still has an intrinsic use value.
\n
Clearly, even prior to the Pizza transaction, the initial miner group attributed value to Bitcoin since they spent their time and the energy consumption of their computers to generate these Bitcoins.
\n
Bitcoin is not the only thing that can be sent via the blockchain, in fact, almost any kind of information can be sent via the transactions, and this is an irreversible process, since any such information will remain in the blockchain for eternity, and everyone in the network will have an access to this information. Bitcoins are the cost of perpetuating the information. In other words, Bitcoins can be regarded as the “real estate” of the blockchain. The more Bitcoins a person has, the more information he can send on the blockchain. There are all kinds of data encapsulated on the blockchain: poems, prays, political statements, commercials, and even photos [36]. In fact, it is amazing how many kinds of information can be found there. It is not difficult to find many applications for this kind of information retention.
\n
One of the special applications is the announcement of contracts. Such contracts will be confirmed by the blockchain. Or another important application is a decentralized registrar of real estate (or any other type of property). With the Bitcoin network, one can announce ownership of objects, the information will be available instantaneously, and since it is not centralized, then there is no fear of losing this information.
\n
The important thing is to realize that there is no direct connection between this information and the value of Bitcoin. The relation is indirect. The value of these announcements is directly related to the number of nodes in the network. The more people are connected to the Bitcoin network, the more valuable this information is. Therefore, if the network is large enough, then people will like to use it by sending and announcing information. However, it is clear that when the network grows, sending information becomes more valuable, and therefore the value of the network’s coin, which controls it, increases as well. The more coins a person owns, the more he controls the network. Again we see that owning Bitcoin is like owning real estate on the blockchain.
\n
Clearly, at its inception, when the Bitcoin network was small, the value of publishing data over it was low, but then the Bitcoin’s value was accordingly small. In fact, in its genesis, the Bitcoin’s value could have been only the subjective value of the first few geeks, who mined it (including Satoshi himself). When the network grows, the Bitcoin value increases exponentially, just like the laser power.
\n
Nowadays, the fees of sending information over the blockchain are quite high, and therefore people seldom use the blockchain for broadcasting information. As a consequence, they tend to forget that the Bitcoin network has a clear nonmonetary use, and therefore it has a subjective use value. In any case, the fact that Bitcoin has a nonzero value does not and cannot contradict Mises’ regression theorem.
\n
\n
\n
24. Conclusions
\n
Bitcoin has many enemies, and, as a consequence, there are many arguments, which allegedly explains, why Bitcoin should be worthless or should be banned. The truth is that Bitcoin is extremely valuable and is here to stay because it cannot be banned. On the other hand, Bitcoin has many advocates, which use inaccurate arguments to justify the origin of its value.
\n
The fact that these arguments were presented by renowned economists shows us that our understanding about the origin of money did not change much during the last century. The mysterious Satoshi Nakamoto gave us the opportunity to revive these century-old conundrums.
\n
The main conclusions are:
Bitcoin is not a scheme; it is a great monetary invention, which has a clear economic value.
It cannot and should not be banned by governments. In fact, any government’s manipulation and regulation emphasize and increase the need for cryptocurrencies.
Criminals are not the only ones who see the benefits in using cryptocurrencies. In the third world (e.g., Venezuela and Zimbabwe), cryptos are lifesavers. In general, cryptos are extremely valuable wherever censorship resistance is required, and in a global market economy, that fact creates value for everyone.
Bitcoin does suffer from infancy problems (high volatility and high transaction costs); however, these issues are not fundamental and will be resolved eventually (we already see many signs for that). The fact that the crypto market exceeded 800B$, despite these issues, only emphasizes the need of the markets in them.
The energy which is spent in crypto mining is not a wasted energy. It is the source of the network’s security which increases the trust in the system, and in a market economy trust is a very valuable commodity.
The easiness in the creation of new coins is not equivalent to fiat money inflation. Fiat inflation is a counterfeiting process, while the creation of new cryptos is equivalent to the creation of a new invention, which may be better, but it has to surmount the former coins’ network effect.
Bitcoin does not contradict any economical law. In particular, it does not contradict Mises’ regression theorem for two grounds: first, Bitcoin was valuable for the first miners even before it was used as a medium of exchange, and the regression process can be kindled by any subjective whim; second, even now Bitcoin has a nonmonetary value (just like gold) as a “real-estate” on the Bitcoin network.
\n
\n\n',keywords:"cryptocurrencies, Bitcoin, blockchain, regression theorem, Mises, Austrian school of economics, the value of money",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/62430.pdf",chapterXML:"https://mts.intechopen.com/source/xml/62430.xml",downloadPdfUrl:"/chapter/pdf-download/62430",previewPdfUrl:"/chapter/pdf-preview/62430",totalDownloads:1268,totalViews:0,totalCrossrefCites:0,dateSubmitted:"February 15th 2018",dateReviewed:"June 12th 2018",datePrePublished:"November 5th 2018",datePublished:"August 28th 2019",dateFinished:"July 3rd 2018",readingETA:"0",abstract:"Bitcoin and other cryptocurrencies received a lot of criticism during the last 9 years. It is not surprising that this criticism came from organizations that are threatened by the crypto revolution (banks, government, central banks, finance companies, etc.). Nevertheless, it is very surprising to hear criticism from economics schools, which oppose central banking and advocate free choice in currencies (such as the Austrian school of economics). Unlike the ordinary criticism (that Bitcoin is a scam, a bubble, etc.), which can easily be refuted, the criticism of part of the Austrian school economists is based on interesting arguments, which requires a different level of explanation. For example, it was claimed that Bitcoin should be worthless; otherwise, it contradicts Mises’ regression theorem. The object of the chapter is twofold: first to explain why the criticism is unfounded and second to analyze the origin of the value of Bitcoin and other cryptocoins from the perspective of the Austrian school of economics. In particular, it is explained that Bitcoin does not contradict the regression theorem for two reasons. First, the initial value estimation can be a random event, and second, the Bitcoin network (even now) has a nonmonetary value.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/62430",risUrl:"/chapter/ris/62430",signatures:"Er'el Granot",book:{id:"7228",type:"book",title:"Blockchain and Cryptocurrencies",subtitle:null,fullTitle:"Blockchain and Cryptocurrencies",slug:"blockchain-and-cryptocurrencies",publishedDate:"August 28th 2019",bookSignature:"Asma Salman and Muthanna G. Abdul Razzaq",coverURL:"https://cdn.intechopen.com/books/images_new/7228.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83881-208-9",printIsbn:"978-1-78923-913-3",pdfIsbn:"978-1-78923-914-0",isAvailableForWebshopOrdering:!0,editors:[{id:"206443",title:"Prof.",name:"Asma",middleName:null,surname:"Salman",slug:"asma-salman",fullName:"Asma Salman"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"181601",title:"Prof.",name:"Er'El",middleName:null,surname:"Granot",fullName:"Er'El Granot",slug:"er'el-granot",email:"erelgranot@gmail.com",position:null,profilePictureURL:"https://images.app.goo.gl/7NdTsPjGLEU1RDBC6",institution:{name:"Ariel University",institutionURL:null,country:{name:"Israel"}}}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Is Bitcoin a Ponzi scheme?",level:"1"},{id:"sec_3",title:"3. Bitcoin is a bubble",level:"1"},{id:"sec_4",title:"4. Bitcoin yields no return",level:"1"},{id:"sec_5",title:"5. The Bitcoin’s volatility",level:"1"},{id:"sec_6",title:"6. The hoarding dilemma",level:"1"},{id:"sec_7",title:"7. A deflationary economy",level:"1"},{id:"sec_8",title:"8. Bitcoin and the government",level:"1"},{id:"sec_9",title:"9. Technology-based money",level:"1"},{id:"sec_10",title:"10. Genuine scarcity",level:"1"},{id:"sec_11",title:"11. Bitcoin transactions are too slow and too expensive",level:"1"},{id:"sec_12",title:"12. Currencies backed by nothing",level:"1"},{id:"sec_13",title:"13. Dependence on the current monetary system",level:"1"},{id:"sec_14",title:"14. Bitcoin and economic calculations",level:"1"},{id:"sec_15",title:"15. Bitcoin and the division of labor",level:"1"},{id:"sec_16",title:"16. Bitcoin and property rights",level:"1"},{id:"sec_17",title:"17. Bitcoin and crime",level:"1"},{id:"sec_18",title:"18. Bitcoin and egalitarianism",level:"1"},{id:"sec_19",title:"19. The value of Bitcoin",level:"1"},{id:"sec_20",title:"20. Backed by energy",level:"1"},{id:"sec_21",title:"21. Too costly to mine",level:"1"},{id:"sec_22",title:"22. Scarcity and value",level:"1"},{id:"sec_23",title:"23. The regression theorem and the origin of value",level:"1"},{id:"sec_24",title:"24. Conclusions",level:"1"}],chapterReferences:[{id:"B1",body:'Kharpal A. WikiLeaks Founder Assange Claims he Made 50,000% Return on Bitcoin Thanks to the US Government. CNBC. October 16, 2017. Available from: https://www.cnbc.com/2017/10/16/wikileaks-julian-assange-bitcoin-50000-percent-return-thanks-to-us-government.html\n\n'},{id:"B2",body:'Lujan S. Bitcoin was Built to Incite Peaceful Anarchy. Bitcoin.com. January 9, 2016. Available from: https://news.bitcoin.com/bitcoin-built-incite-peaceful-anarchy/\n\n'},{id:"B3",body:'del Castillo M. Guns & Crypto: How Bitcoin is Helping Keep Cody Wilson\'s Anarchist Dream Alive. October 1, 2017. Available from: https://www.coindesk.com/guns-crypto-bitcoin-helping-keep-cody-wilsons-anarchist-dream-alive/\n\n'},{id:"B4",body:'Kim T. Seth Klarman Calls Bitcoin a ‘Trading Sardine,’ Others Say ‘Speculative Mania’—They are Right. CNBC. December 15, 2017. Available from: https://www.cnbc.com/2017/12/15/seth-klarman-calls-bitcoin-a-trading-sardine-others-say-speculative-mania--they-are-right.html\n\n'},{id:"B5",body:'Torres C. Yellen Says Bitcoin Is a ‘Highly Speculative Asset’. Bloomberg Technology. December 13, 2017. Available from: https://www.bloomberg.com/news/articles/2017-12-13/yellen-says-cryptocurrency-bitcoin-is-highly-speculative-asset\n\n'},{id:"B6",body:'Gil-Pulgar J. Former Chairman of the U.S. Federal Reserve Alan Greenspan argues: Bitcoin is not rational. Bitcoin News. December 8, 2017. Available from: http://bitcoinist.com/greenspan-declares-bitcoin-irrational/\n\n'},{id:"B7",body:'Pollock D. Billionaire Investor Warns Bitcoin is Pyramid Scheme. Cointelegraph. July 27, 2017. Available from: https://cointelegraph.com/news/billionaire-investor-warns-bitcoin-is-pyramid-scheme\n\n'},{id:"B8",body:'Lovelace B Jr. Warren Buffett Watcher Echoes Warning on Bitcoin: We\'re Probably near the Top of a bubble. CNBC. January 11, 2018. Available from: https://www.cnbc.com/2018/01/11/warren-buffett-watcher-were-near-the-top-of-a-bitcoin-bubble.html\n\n'},{id:"B9",body:'Nullen C. Bitcoin is Worthless, Bubble May Pop Soon, Allianz Global Says. Bloomberg Businesweek. March 14, 2018. Available from: https://www.bloomberg.com/news/articles/2018-03-14/bitcoin-is-worthless-bubble-may-pop-soon-allianz-global-says\n\n'},{id:"B10",body:'North G. Bitcoins: The Second Biggest Ponzi Scheme in History. November 29, 2013. Available from: https://www.garynorth.com/public/11828.cfm\n\n'},{id:"B11",body:'Bennington A. Bitcoin Bear Peter Schiff Doubles Down: Even at $4,000 it\'s Still a ‘Bubble’. Coindesk. August 17, 2017. 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Auburn, AL: Ludwig von Mises Institute; 1940/1998. Available from: http://mises.org/document/3250/Human-Action\n\n'},{id:"B17",body:'Rothbard Murray N. Man, Economy, and State, with Power and Market. Auburn, AL: Mises Institute; 1970. Available from: http://mises.org/document/1082/Man-Economy-and-State-with-Power-and-Market\n\n'},{id:"B18",body:'Herbener JM. The Pure Time-Preference Theory of Interest. Auburn, Alabama: CreateSpace Independent Publishing Platform; 2011\n'},{id:"B19",body:'Hayek F. “The ‘Paradox‘ of Saving”. Originally Appeared in the Zeitschrift für Nationalökonomie, Bd. I, Heft III, 1929, Under the Title “Gibt es einen Widersinn des Sparens?. The Translation is the Work of Mr. Nicholas Kaldor and Dr. Georg Tugendhat and was First Published in Economica, May, 1931\n'},{id:"B20",body:'Bordo MD, Lane JL, Redish A. Good versus bad deflation: Lessons from the gold standard era. NBER (The National Bureau of Economic Research) Working Paper No. 10329; February, 2004. Available from: http://www.nber.org/papers/w10329\n\n'},{id:"B21",body:'Lewis N. Let\'s Resolve the Gold Standard ‘Deflation’ Fallacy. Forbes, Economics & Finance. May 21, 2015. Available from: https://www.forbes.com/sites/nathanlewis/2015/11/21/lets-resolve-the-gold-standard-deflation-fallacy/\n\n'},{id:"B22",body:'Karsten J, West DM. Venezuela’s “Petro” Undermines other Cryptocurrencies–and International Sanctions. Brookings. March 9, 2018. Available from: https://www.brookings.edu/blog/techtank/2018/03/09/venezuelas-petro-undermines-other-cryptocurrencies-and-international-sanctions/\n\n'},{id:"B23",body:'Hosia H, Perry N. This is the First Country to Adopt a Cryptocurrency as its Official Currency. Time. March 5, 2018. Available from: http://time.com/money/5186316/this-is-the-first-country-to-adopt-a-cryptocurrency-as-its-official-currency/\n\n'},{id:"B24",body:'Althauser J. Race Towards the First ‘Crypto-Country’ in the World. Cointelegraph. October 13, 2017. Available from: https://cointelegraph.com/news/race-towards-the-first-crypto-country-in-the-world\n\n'},{id:"B25",body:'Foote C, Block W, Crane K, Gray S, et al. Economic policy and prospects in Iraq. The Journal of Economic Perspectives. 2004;18(3):47-70\n'},{id:"B26",body:'Granot E. Ricardo\'s law of comparative advantage and the Law of Association: A subjective analysis. In: Economics and Development. Rijeka, Croatia: Intech; 2017. Chapter 3\n'},{id:"B27",body:'Kinsella S. Against Intellectual Property. Auburn, AL: Mises Institute; 2008\n'},{id:"B28",body:'Sampathkumar M. Bitcoin should be ‘Outlawed’, says Nobel Prize-Winning The Economist. Independent. November 30, 2017. Available from: https://www.independent.co.uk/news/business/bitcoin-latest-news-outlawed-nobel-prize-winner-joseph-stiglitz-comments-a8083416.html\n\n'},{id:"B29",body:'Smart E. 1% of the Bitcoin Community Controls 99% of Bitcoin Wealth. CCN. May 18, 2015. Available from: https://www.ccn.com/1-bitcoin-community-controls-99-bitcoin-wealth/\n\n'},{id:"B30",body:'John McAfee Ups Bitcoin Target Price to $1 Million by End 2020. Available from: https://www.youtube.com/watch?v=bo9zaBZ1VIo&t=917s\n\n'},{id:"B31",body:'Salerno J. Money, Sound and Unsound. Auburn, Alabama: Mises Institute; 2010\n'},{id:"B32",body:'Helfferich EG. Das Geld [English Translation, “Money”]. London: Ernest Benn; 1927\n'},{id:"B33",body:'Menger C. Principles of Economics. Auburn, Alabama: The Mises Institute; 2004\n'},{id:"B34",body:'von Mises L. The Theory of Money and Credit. New Haven: Yale University Press; 1912/1953. Translated by Batson HE\n'},{id:"B35",body:'Graf Konrad S. IN-DEPTH | Bitcoins, the Regression Theorem, and that Curious but Unthreatening Empirical World. February 27, 2013. Available from: http://konradsgraf.com/blog1/2013/2/27/in-depth-bitcoins-the-regression-theorem-and-that-curious-bu.html\n\n'},{id:"B36",body:'Shirriff K. Hidden Surprises in the Bitcoin Blockchain and how they Are Stored: Nelson Mandela, Wikileaks, Photos, and Python Software. Available from: http://www.righto.com/2014/02/ascii-bernanke-wikileaks-photographs.html\n\n'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Er'el Granot",address:"erel@ariel.ac.il",affiliation:'
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Abdel Rahman, Robert J. Helleur, Mohamed F. Jeebhay and Andreas L. Lopata",authors:[{id:"62982",title:"Dr.",name:"Anas",middleName:"M",surname:"Abdel Rahman",slug:"anas-abdel-rahman",fullName:"Anas Abdel Rahman"},{id:"115468",title:"Prof.",name:"Robert",middleName:null,surname:"Helleur",slug:"robert-helleur",fullName:"Robert Helleur"},{id:"115470",title:"Prof.",name:"Mohamed",middleName:"Fareed",surname:"Jeebhay",slug:"mohamed-jeebhay",fullName:"Mohamed Jeebhay"},{id:"115472",title:"Associate Prof.",name:"Andreas",middleName:null,surname:"Lopata",slug:"andreas-lopata",fullName:"Andreas Lopata"}]},{id:"55777",doi:"10.5772/intechopen.69361",title:"Food Allergen Analysis: Detection, Quantification and Validation by Mass Spectrometry",slug:"food-allergen-analysis-detection-quantification-and-validation-by-mass-spectrometry",totalDownloads:2208,totalCrossrefCites:3,totalDimensionsCites:12,abstract:"Worldwide, food-allergy-related diseases are a significant health problem. While the food industry works on managing cross-contaminations and while clinicians deal with treatment, laboratories must develop efficient analytical methods to ensure detection of hidden allergens that can cause severe adverse reactions. Over the past few years, huge progress has been made in mass spectrometry for the analysis of allergens in incurred and processed foodstuffs, especially as regards sample preparation and enrichment (solid phase extraction, protein precipitation and ultrafiltration). These achievements make it possible to meet the Allergen Bureau's Voluntary Incidental Trace Allergen Labelling (VITAL) sensitivity criteria. The present chapter details the different steps in the development of mass spectrometry methods, from peptide selection to the validation of qualitative and quantitative methods. The chapter focuses mainly on studies performed with incurred and processed food samples to ensure the applicability of the methods to allergen detection in real food products.",book:{id:"5776",slug:"allergen",title:"Allergen",fullTitle:"Allergen"},signatures:"Mélanie Planque, Thierry Arnould and Nathalie Gillard",authors:[{id:"203796",title:"Ph.D. Student",name:"Planque",middleName:null,surname:"Mélanie",slug:"planque-melanie",fullName:"Planque Mélanie"},{id:"209110",title:"Dr.",name:"Nathalie",middleName:null,surname:"Gillard",slug:"nathalie-gillard",fullName:"Nathalie Gillard"},{id:"209111",title:"Prof.",name:"Thierry",middleName:null,surname:"Arnould",slug:"thierry-arnould",fullName:"Thierry Arnould"}]},{id:"22365",doi:"10.5772/20149",title:"Contribution of Peroxynitrite, a Reactive Nitrogen Species, in the Pathogenesis of Autoimmunity",slug:"contribution-of-peroxynitrite-a-reactive-nitrogen-species-in-the-pathogenesis-of-autoimmunity",totalDownloads:2244,totalCrossrefCites:5,totalDimensionsCites:11,abstract:null,book:{id:"280",slug:"autoimmune-disorders-pathogenetic-aspects",title:"Autoimmune Disorders",fullTitle:"Autoimmune Disorders - Pathogenetic Aspects"},signatures:"Rizwan Ahmad and Haseeb Ahsan",authors:[{id:"37607",title:"Dr.",name:"Haseeb",middleName:null,surname:"Ahsan",slug:"haseeb-ahsan",fullName:"Haseeb Ahsan"},{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad"}]},{id:"31790",doi:"10.5772/26234",title:"Microbiota and Allergy: From Dysbiosis to Probiotics",slug:"microbiota-and-allergy-from-dysbiosis-to-probiotics",totalDownloads:3494,totalCrossrefCites:2,totalDimensionsCites:9,abstract:null,book:{id:"934",slug:"allergic-diseases-highlights-in-the-clinic-mechanisms-and-treatment",title:"Allergic Diseases",fullTitle:"Allergic Diseases - Highlights in the Clinic, Mechanisms and Treatment"},signatures:"Anne-Judith Waligora-Dupriet and Marie-José Butel",authors:[{id:"65930",title:"Dr.",name:"Anne-Judith",middleName:null,surname:"Waligora-Dupriet",slug:"anne-judith-waligora-dupriet",fullName:"Anne-Judith Waligora-Dupriet"},{id:"69522",title:"Prof.",name:"Marie-José",middleName:null,surname:"Butel",slug:"marie-jose-butel",fullName:"Marie-José Butel"}]}],mostDownloadedChaptersLast30Days:[{id:"71952",title:"Pathology of Sarcoidosis and Differential Diagnostics of other Granulomatous Diseases",slug:"pathology-of-sarcoidosis-and-differential-diagnostics-of-other-granulomatous-diseases",totalDownloads:828,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Granulomatous diseases are the heterogeneous group of the conditions of different etiologies with a variety of clinic syndromes and morphological features and nonuniform sensitivity to therapy, and the existence of granulomas as general dominate histological expression. Granuloma is indicative of chronic inflammation involving cells of the macrophage system and other inflammatory cells. After the antigen exposure, the activation of T-lymphocytes, macrophages, and epithelioid histiocytes leads to granuloma formation. Granuloma also contains the extracellular matrix produced by fibroblasts, which provide the boundary and isolation of antigen. Their etiology may classify granulomatous diseases as infectious and noninfectious. However, recent studies demonstrate that pathogenic microorganisms may cause the granuloma formation in diseases previously considered as noninfectious. In some cases, differentiation between infectious and noninfectious processes may be problematic. This chapter aims to highlight the multiformity of granulomatous diseases, characterize the pathologic features of different infectious and noninfectious granulomatosis, and delineate the diagnostic approach.",book:{id:"7168",slug:"sarcoidosis-and-granulomatosis-diagnosis-and-management",title:"Sarcoidosis and Granulomatosis",fullTitle:"Sarcoidosis and Granulomatosis - Diagnosis and Management"},signatures:"Maria V. Samsonova and Andrey L. Chernyaev",authors:[{id:"311531",title:"Dr.",name:"Maria",middleName:"Viktorovna",surname:"Samsonova",slug:"maria-samsonova",fullName:"Maria Samsonova"}]},{id:"55279",title:"Mechanism of Action of Nonsteroidal Anti-Inflammatory Drugs",slug:"mechanism-of-action-of-nonsteroidal-anti-inflammatory-drugs",totalDownloads:4799,totalCrossrefCites:9,totalDimensionsCites:19,abstract:"The use of nonsteroidal anti-inflammatory drugs (NSAIDs) dates back to thousands of years when man used natural sources of these agents in a lot of pain and inflammatory conditions. The tone for modern day discovery and use of NSAIDs was set with the discovery of aspirin. Today in addition to aspirin, a host of other NSAIDs of varying potency and efficacy is employed in the management of pain and inflammatory conditions. This chapter looks with key interest in the existing and evolving role of NSAIDs in therapeutics with emphasis on the current insights into their mechanism of action and side effect profiles associated with its use in pain and inflammation as well as its potential therapeutic benefits in cancer chemotherapy.",book:{id:"5872",slug:"nonsteroidal-anti-inflammatory-drugs",title:"Nonsteroidal Anti-Inflammatory Drugs",fullTitle:"Nonsteroidal Anti-Inflammatory Drugs"},signatures:"Newman Osafo, Christian Agyare, David Darko Obiri and Aaron\nOpoku Antwi",authors:[{id:"182058",title:"Dr.",name:"Christian",middleName:null,surname:"Agyare",slug:"christian-agyare",fullName:"Christian Agyare"},{id:"196452",title:"Dr.",name:"Newman",middleName:null,surname:"Osafo",slug:"newman-osafo",fullName:"Newman Osafo"},{id:"197415",title:"Prof.",name:"David",middleName:null,surname:"Darko Obiri",slug:"david-darko-obiri",fullName:"David Darko Obiri"},{id:"197428",title:"Mr.",name:"Aaron",middleName:null,surname:"Antwi",slug:"aaron-antwi",fullName:"Aaron Antwi"}]},{id:"31773",title:"Enzymatic and Chemical Modifications of Food Allergens",slug:"enzymatic-and-chemical-modifications-of-food-allergens",totalDownloads:3774,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"934",slug:"allergic-diseases-highlights-in-the-clinic-mechanisms-and-treatment",title:"Allergic Diseases",fullTitle:"Allergic Diseases - Highlights in the Clinic, Mechanisms and Treatment"},signatures:"Dragana Stanić-Vučinić and Tanja Ćirković Veličković",authors:[{id:"69834",title:"Dr.",name:"Dragana",middleName:null,surname:"Stanic-Vucinic",slug:"dragana-stanic-vucinic",fullName:"Dragana Stanic-Vucinic"},{id:"69858",title:"Prof.",name:"Tanja",middleName:null,surname:"Cirkovic Velickovic",slug:"tanja-cirkovic-velickovic",fullName:"Tanja Cirkovic Velickovic"}]},{id:"49960",title:"Asthma-COPD Overlap Syndrome (ACOS): Current Understanding and Future Perspectives",slug:"asthma-copd-overlap-syndrome-acos-current-understanding-and-future-perspectives",totalDownloads:2253,totalCrossrefCites:4,totalDimensionsCites:4,abstract:"This chapter resumes our current understanding of asthma–chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS), pretending to offer a comprehensive approach for the practicing physician, and provides some future perspectives on this entity.",book:{id:"5126",slug:"asthma-from-childhood-asthma-to-acos-phenotypes",title:"Asthma",fullTitle:"Asthma - From Childhood Asthma to ACOS Phenotypes"},signatures:"Irina Bobolea and Luis Alejandro Pérez de Llano",authors:[{id:"178233",title:"Dr.",name:"Irina",middleName:null,surname:"Bobolea",slug:"irina-bobolea",fullName:"Irina Bobolea"},{id:"178739",title:"Dr.",name:"Luis Alejandro",middleName:null,surname:"Pérez De Llano",slug:"luis-alejandro-perez-de-llano",fullName:"Luis Alejandro Pérez De Llano"}]},{id:"54761",title:"Adverse Effects and Drug Interactions of the Non‐Steroidal Anti‐Inflammatory Drugs",slug:"adverse-effects-and-drug-interactions-of-the-non-steroidal-anti-inflammatory-drugs",totalDownloads:2980,totalCrossrefCites:3,totalDimensionsCites:8,abstract:"The aim of this chapter is to increase the awareness of health‐care professionals concerning potential adverse effects and drug interactions of non‐steroidal anti‐inflammatory drugs (NSAIDs), which are among the most widely prescribed medicines, globally. They have a variety of clinical applications due to their anti‐inflammatory, analgesic, antipyretic, or antithrombotic effect, but these drugs are not entirely innocuous, since they could increase the risk of gastrointestinal and cardiovascular complications. Furthermore, the drugs from this class have the potential of altering the pharmacokinetics of associated drugs, and also pharmacodynamic interactions have been reported. The clinical significance, mechanisms, and epidemiology of the adverse effects and drug interactions of NSAIDs are presented in this chapter. Prevention strategies for particularly high‐risk groups of patients are also exposed. Detailed and up‐to‐date information regarding the adverse effects and drug interactions of NSAIDs are needed for all healthcare professionals in order to maximize efficacy in treating various illnesses while minimizing the risks for the patients.",book:{id:"5872",slug:"nonsteroidal-anti-inflammatory-drugs",title:"Nonsteroidal Anti-Inflammatory Drugs",fullTitle:"Nonsteroidal Anti-Inflammatory Drugs"},signatures:"Oliviu Vostinaru",authors:[{id:"198574",title:"Dr.",name:"Oliviu",middleName:null,surname:"Vostinaru",slug:"oliviu-vostinaru",fullName:"Oliviu Vostinaru"}]}],onlineFirstChaptersFilter:{topicId:"1035",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:0,limit:8,total:null},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:99,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:290,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:10,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:1,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:12,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. 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He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. 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Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. Board Member and Chair of Mycology Group of Chinese Society of Dermatology.",institutionString:null,institution:{name:"Sichuan University",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null},{id:"5",title:"Parasitic Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",isOpenForSubmission:!0,annualVolume:11401,editor:{id:"67907",title:"Dr.",name:"Amidou",middleName:null,surname:"Samie",slug:"amidou-samie",fullName:"Amidou Samie",profilePictureURL:"https://mts.intechopen.com/storage/users/67907/images/system/67907.jpg",biography:"Dr. Amidou Samie is an Associate Professor of Microbiology at the University of Venda, in South Africa, where he graduated for his PhD in May 2008. He joined the Department of Microbiology the same year and has been giving lectures on topics covering parasitology, immunology, molecular biology and industrial microbiology. He is currently a rated researcher by the National Research Foundation of South Africa at category C2. He has published widely in the field of infectious diseases and has overseen several MSc’s and PhDs. His research activities mostly cover topics on infectious diseases from epidemiology to control. His particular interest lies in the study of intestinal protozoan parasites and opportunistic infections among HIV patients as well as the potential impact of childhood diarrhoea on growth and child development. He also conducts research on water-borne diseases and water quality and is involved in the evaluation of point-of-use water treatment technologies using silver and copper nanoparticles in collaboration with the University of Virginia, USA. 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His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University, Kuwait. 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He is also an editor and editor in chief for various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:null},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:"Beijing University of Technology",institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Lakhno Igor Victorovich was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPhD – 1999, Kharkiv National Medical Univesity.\nDSc – 2019, PL Shupik National Academy of Postgraduate Education \nLakhno Igor has been graduated from an international training courses on reproductive medicine and family planning held in Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor of the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s a professor of the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education . He’s an author of about 200 printed works and there are 17 of them in Scopus or Web of Science databases. Lakhno Igor is a rewiever of Journal of Obstetrics and Gynaecology (Taylor and Francis), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for DSc degree \\'Pre-eclampsia: prediction, prevention and treatment”. Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: obstetrics, women’s health, fetal medicine, cardiovascular medicine.",institutionString:"V.N. Karazin Kharkiv National University",institution:{name:"Kharkiv Medical Academy of Postgraduate Education",country:{name:"Ukraine"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"243698",title:"M.D.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:"Shanxi Eye Hospital",institution:{name:"Shanxi Eye Hospital",country:{name:"China"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRZkkQAG/Profile_Picture_2022-05-09T12:55:18.jpg",biography:null,institutionString:null,institution:null},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. 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This includes, but is not limited to: single-neuron modeling, sensory processing, motor control, memory, and synaptic plasticity, attention, identification, categorization, discrimination, learning, development, axonal patterning, guidance, neural architecture, behaviors, and dynamics of networks, cognition and the neuroscientific basis of consciousness. 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For example, some of the issues of interest could be the following: Advances in evolutionary computation (Genetic algorithms, Genetic programming, Bio-inspired metaheuristics, Hybrid metaheuristics, Parallel ECs); Applications of evolutionary algorithms (Machine learning and Data Mining with EAs, Search-Based Software Engineering, Scheduling, and Planning Applications, Smart Transport Applications, Applications to Games, Image Analysis, Signal Processing and Pattern Recognition, Applications to Sustainability).",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",keywords:"Genetic Algorithms, Genetic Programming, Evolutionary Programming, Evolution Strategies, Hybrid Algorithms, Bioinspired Metaheuristics, Ant Colony Optimization, Evolutionary Learning, Hyperparameter Optimization"},{id:"26",title:"Machine Learning and Data Mining",scope:"The scope of machine learning and data mining is immense and is growing every day. It has become a massive part of our daily lives, making predictions based on experience, making this a fascinating area that solves problems that otherwise would not be possible or easy to solve. This topic aims to encompass algorithms that learn from experience (supervised and unsupervised), improve their performance over time and enable machines to make data-driven decisions. It is not limited to any particular applications, but contributions are encouraged from all disciplines.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/26.jpg",keywords:"Intelligent Systems, Machine Learning, Data Science, Data Mining, Artificial Intelligence"},{id:"27",title:"Multi-Agent Systems",scope:"Multi-agent systems are recognised as a state of the art field in Artificial Intelligence studies, which is popular due to the usefulness in facilitation capabilities to handle real-world problem-solving in a distributed fashion. 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We welcome chapters presenting research on the many applications of multi-agent studies including, but not limited to, the following key areas: machine learning for multi-agent systems; modeling swarms robots and flocks of UAVs with multi-agent systems; decision science and multi-agent systems; software engineering for and with multi-agent systems; tools and technologies of multi-agent systems.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/27.jpg",keywords:"Collaborative Intelligence, Learning, Distributed Control System, Swarm Robotics, Decision Science, Software Engineering"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:{id:"25",title:"Environmental Sciences",doi:"10.5772/intechopen.100362",issn:"2754-6713",scope:"
\r\n\tScientists have long researched to understand the environment and man’s place in it. The search for this knowledge grows in importance as rapid increases in population and economic development intensify humans’ stresses on ecosystems. Fortunately, rapid increases in multiple scientific areas are advancing our understanding of environmental sciences. Breakthroughs in computing, molecular biology, ecology, and sustainability science are enhancing our ability to utilize environmental sciences to address real-world problems. \r\n\tThe four topics of this book series - Pollution; Environmental Resilience and Management; Ecosystems and Biodiversity; and Water Science - will address important areas of advancement in the environmental sciences. They will represent an excellent initial grouping of published works on these critical topics.
",coverUrl:"https://cdn.intechopen.com/series/covers/25.jpg",latestPublicationDate:"April 13th, 2022",hasOnlineFirst:!1,numberOfOpenTopics:4,numberOfPublishedChapters:9,numberOfPublishedBooks:1,editor:{id:"197485",title:"Dr.",name:"J. Kevin",middleName:null,surname:"Summers",fullName:"J. Kevin Summers",profilePictureURL:"https://mts.intechopen.com/storage/users/197485/images/system/197485.jpg",biography:"J. Kevin Summers is a Senior Research Ecologist at the Environmental Protection Agency’s (EPA) Gulf Ecosystem Measurement and Modeling Division. He is currently working with colleagues in the Sustainable and Healthy Communities Program to develop an index of community resilience to natural hazards, an index of human well-being that can be linked to changes in the ecosystem, social and economic services, and a community sustainability tool for communities with populations under 40,000. He leads research efforts for indicator and indices development. Dr. Summers is a systems ecologist and began his career at the EPA in 1989 and has worked in various programs and capacities. This includes leading the National Coastal Assessment in collaboration with the Office of Water which culminated in the award-winning National Coastal Condition Report series (four volumes between 2001 and 2012), and which integrates water quality, sediment quality, habitat, and biological data to assess the ecosystem condition of the United States estuaries. He was acting National Program Director for Ecology for the EPA between 2004 and 2006. He has authored approximately 150 peer-reviewed journal articles, book chapters, and reports and has received many awards for technical accomplishments from the EPA and from outside of the agency. Dr. Summers holds a BA in Zoology and Psychology, an MA in Ecology, and Ph.D. in Systems Ecology/Biology.",institutionString:null,institution:{name:"Environmental Protection Agency",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"38",title:"Pollution",keywords:"Human activity, Pollutants, Reduced risks, Population growth, Waste disposal, Remediation, Clean environment",scope:"
\r\n\tPollution is caused by a wide variety of human activities and occurs in diverse forms, for example biological, chemical, et cetera. In recent years, significant efforts have been made to ensure that the environment is clean, that rigorous rules are implemented, and old laws are updated to reduce the risks towards humans and ecosystems. However, rapid industrialization and the need for more cultivable sources or habitable lands, for an increasing population, as well as fewer alternatives for waste disposal, make the pollution control tasks more challenging. Therefore, this topic will focus on assessing and managing environmental pollution. It will cover various subjects, including risk assessment due to the pollution of ecosystems, transport and fate of pollutants, restoration or remediation of polluted matrices, and efforts towards sustainable solutions to minimize environmental pollution.
",annualVolume:11966,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/38.jpg",editor:{id:"110740",title:"Dr.",name:"Ismail M.M.",middleName:null,surname:"Rahman",fullName:"Ismail M.M. Rahman",profilePictureURL:"https://mts.intechopen.com/storage/users/110740/images/2319_n.jpg",institutionString:null,institution:{name:"Fukushima University",institutionURL:null,country:{name:"Japan"}}},editorTwo:{id:"201020",title:"Dr.",name:"Zinnat Ara",middleName:null,surname:"Begum",fullName:"Zinnat Ara Begum",profilePictureURL:"https://mts.intechopen.com/storage/users/201020/images/system/201020.jpeg",institutionString:null,institution:{name:"Fukushima University",institutionURL:null,country:{name:"Japan"}}},editorThree:null,editorialBoard:[{id:"252368",title:"Dr.",name:"Meng-Chuan",middleName:null,surname:"Ong",fullName:"Meng-Chuan Ong",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRVotQAG/Profile_Picture_2022-05-20T12:04:28.jpg",institutionString:null,institution:{name:"Universiti Malaysia Terengganu",institutionURL:null,country:{name:"Malaysia"}}},{id:"63465",title:"Prof.",name:"Mohamed Nageeb",middleName:null,surname:"Rashed",fullName:"Mohamed Nageeb Rashed",profilePictureURL:"https://mts.intechopen.com/storage/users/63465/images/system/63465.gif",institutionString:null,institution:{name:"Aswan University",institutionURL:null,country:{name:"Egypt"}}},{id:"187907",title:"Dr.",name:"Olga",middleName:null,surname:"Anne",fullName:"Olga Anne",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBE5QAO/Profile_Picture_2022-04-07T09:42:13.png",institutionString:null,institution:{name:"Klaipeda State University of Applied Sciences",institutionURL:null,country:{name:"Lithuania"}}}]},{id:"39",title:"Environmental Resilience and Management",keywords:"Anthropic effects, Overexploitation, Biodiversity loss, Degradation, Inadequate Management, SDGs adequate practices",scope:"
\r\n\tThe environment is subject to severe anthropic effects. Among them are those associated with pollution, resource extraction and overexploitation, loss of biodiversity, soil degradation, disorderly land occupation and planning, and many others. These anthropic effects could potentially be caused by any inadequate management of the environment. However, ecosystems have a resilience that makes them react to disturbances which mitigate the negative effects. It is critical to understand how ecosystems, natural and anthropized, including urban environments, respond to actions that have a negative influence and how they are managed. It is also important to establish when the limits marked by the resilience and the breaking point are achieved and when no return is possible. The main focus for the chapters is to cover the subjects such as understanding how the environment resilience works, the mechanisms involved, and how to manage them in order to improve our interactions with the environment and promote the use of adequate management practices such as those outlined in the United Nations’ Sustainable Development Goals.
",annualVolume:11967,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/39.jpg",editor:{id:"137040",title:"Prof.",name:"Jose",middleName:null,surname:"Navarro-Pedreño",fullName:"Jose Navarro-Pedreño",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRAXrQAO/Profile_Picture_2022-03-09T15:50:19.jpg",institutionString:"Miguel Hernández University of Elche, Spain",institution:null},editorTwo:null,editorThree:null,editorialBoard:[{id:"177015",title:"Prof.",name:"Elke Jurandy",middleName:null,surname:"Bran Nogueira Cardoso",fullName:"Elke Jurandy Bran Nogueira Cardoso",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRGxzQAG/Profile_Picture_2022-03-25T08:32:33.jpg",institutionString:"Universidade de São Paulo, Brazil",institution:null},{id:"211260",title:"Dr.",name:"Sandra",middleName:null,surname:"Ricart",fullName:"Sandra Ricart",profilePictureURL:"https://mts.intechopen.com/storage/users/211260/images/system/211260.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}}]},{id:"40",title:"Ecosystems and Biodiversity",keywords:"Ecosystems, Biodiversity, Fauna, Taxonomy, Invasive species, Destruction of habitats, Overexploitation of natural resources, Pollution, Global warming, Conservation of natural spaces, Bioremediation",scope:"
\r\n\tIn general, the harsher the environmental conditions in an ecosystem, the lower the biodiversity. Changes in the environment caused by human activity accelerate the impoverishment of biodiversity.
\r\n
\r\n\tBiodiversity refers to “the variability of living organisms from any source, including terrestrial, marine and other aquatic ecosystems and the ecological complexes of which they are part; it includes diversity within each species, between species, and that of ecosystems”.
\r\n
\r\n\tBiodiversity provides food security and constitutes a gene pool for biotechnology, especially in the field of agriculture and medicine, and promotes the development of ecotourism.
\r\n
\r\n\tCurrently, biologists admit that we are witnessing the first phases of the seventh mass extinction caused by human intervention. It is estimated that the current rate of extinction is between a hundred and a thousand times faster than it was when man first appeared. The disappearance of species is caused not only by an accelerated rate of extinction, but also by a decrease in the rate of emergence of new species as human activities degrade the natural environment. The conservation of biological diversity is "a common concern of humanity" and an integral part of the development process. Its objectives are “the conservation of biological diversity, the sustainable use of its components, and the fair and equitable sharing of the benefits resulting from the use of genetic resources”.
\r\n
\r\n\tThe following are the main causes of biodiversity loss:
\r\n
\r\n\t• The destruction of natural habitats to expand urban and agricultural areas and to obtain timber, minerals and other natural resources.
\r\n
\r\n\t• The introduction of alien species into a habitat, whether intentionally or unintentionally which has an impact on the fauna and flora of the area, and as a result, they are reduced or become extinct.
\r\n
\r\n\t• Pollution from industrial and agricultural products, which devastate the fauna and flora, especially those in fresh water.
\r\n
\r\n\t• Global warming, which is seen as a threat to biological diversity, and will become increasingly important in the future.
",annualVolume:11968,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/40.jpg",editor:{id:"209149",title:"Prof.",name:"Salustiano",middleName:null,surname:"Mato",fullName:"Salustiano Mato",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRLREQA4/Profile_Picture_2022-03-31T10:23:50.png",institutionString:null,institution:{name:"University of Vigo",institutionURL:null,country:{name:"Spain"}}},editorTwo:{id:"60498",title:"Prof.",name:"Josefina",middleName:null,surname:"Garrido",fullName:"Josefina Garrido",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRj1VQAS/Profile_Picture_2022-03-31T10:06:51.jpg",institutionString:null,institution:{name:"University of Vigo",institutionURL:null,country:{name:"Spain"}}},editorThree:{id:"464288",title:"Dr.",name:"Francisco",middleName:null,surname:"Ramil",fullName:"Francisco Ramil",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003RI7lHQAT/Profile_Picture_2022-03-31T10:15:35.png",institutionString:null,institution:{name:"University of Vigo",institutionURL:null,country:{name:"Spain"}}},editorialBoard:[{id:"220987",title:"Dr.",name:"António",middleName:"Onofre",surname:"Soares",fullName:"António Soares",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRNtzQAG/Profile_Picture_1644499672340",institutionString:null,institution:{name:"University of the Azores",institutionURL:null,country:{name:"Portugal"}}}]},{id:"41",title:"Water Science",keywords:"Water, Water resources, Freshwater, Hydrological processes, Utilization, Protection",scope:"
\r\n\tWater is not only a crucial substance needed for biological life on Earth, but it is also a basic requirement for the existence and development of the human society. Owing to the importance of water to life on Earth, early researchers conducted numerous studies and analyses on the liquid form of water from the perspectives of chemistry, physics, earth science, and biology, and concluded that Earth is a "water polo". Water covers approximately 71% of Earth's surface. However, 97.2% of this water is seawater, 21.5% is icebergs and glaciers, and only 0.65% is freshwater that can be used directly by humans. As a result, the amount of water reserves available for human consumption is limited. The development, utilization, and protection of freshwater resources has become the focus of water science research for the continued improvement of human livelihoods and society.
\r\n
\r\n\tWater exists as solid, liquid, and gas within Earth’s atmosphere, lithosphere, and biosphere. Liquid water is used for a variety of purposes besides drinking, including power generation, ecology, landscaping, and shipping. Because water is involved in various environmental hydrological processes as well as numerous aspects of the economy and human society, the study of various phenomena in the hydrosphere, the laws governing their occurrence and development, the relationship between the hydrosphere and other spheres of Earth, and the relationship between water and social development, are all part of water science. Knowledge systems for water science are improving continuously. Water science has become a specialized field concerned with the identification of its physical, chemical, and biological properties. In addition, it reveals the laws of water distribution, movement, and circulation, and proposes methods and tools for water development, utilization, planning, management, and protection. Currently, the field of water science covers research related to topics such as hydrology, water resources and water environment. It also includes research on water related issues such as safety, engineering, economy, law, culture, information, and education.
",annualVolume:11969,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/41.jpg",editor:{id:"349630",title:"Dr.",name:"Yizi",middleName:null,surname:"Shang",fullName:"Yizi Shang",profilePictureURL:"https://mts.intechopen.com/storage/users/349630/images/system/349630.jpg",institutionString:"China Institute of Water Resources and Hydropower Research",institution:{name:"China Institute of Water Resources and Hydropower Research",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"216491",title:"Dr.",name:"Charalampos",middleName:null,surname:"Skoulikaris",fullName:"Charalampos Skoulikaris",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRMsbQAG/Profile_Picture_2022-04-21T09:31:55.jpg",institutionString:null,institution:{name:"Aristotle University of Thessaloniki",institutionURL:null,country:{name:"Greece"}}},{id:"300124",title:"Prof.",name:"Thomas",middleName:null,surname:"Shahady",fullName:"Thomas Shahady",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002kuIgmQAE/Profile_Picture_2022-03-18T07:32:10.jpg",institutionString:null,institution:{name:"Lynchburg College",institutionURL:null,country:{name:"United States of America"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/31654",hash:"",query:{},params:{id:"31654"},fullPath:"/chapters/31654",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()