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\r\n\r\nVitamin K2 - Vital for Health and Wellbeing has been produced and distributed through the support from Kappa Bioscience, Norway.\r\n',isbn:"978-953-51-3020-8",printIsbn:"978-953-51-3019-2",pdfIsbn:"978-953-51-4895-1",doi:"10.5772/61430",price:139,priceEur:155,priceUsd:179,slug:"vitamin-k2-vital-for-health-and-wellbeing",numberOfPages:338,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"b2f9f024939ddc4f5da2a8afa3fcd9c9",bookSignature:"Jan Oxholm Gordeladze",publishedDate:"March 22nd 2017",coverURL:"https://cdn.intechopen.com/books/images_new/5169.jpg",numberOfDownloads:35120,numberOfWosCitations:31,numberOfCrossrefCitations:28,numberOfCrossrefCitationsByBook:4,numberOfDimensionsCitations:50,numberOfDimensionsCitationsByBook:4,hasAltmetrics:1,numberOfTotalCitations:109,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"October 6th 2015",dateEndSecondStepPublish:"January 31st 2016",dateEndThirdStepPublish:"March 25th 2016",dateEndFourthStepPublish:"May 30th 2016",dateEndFifthStepPublish:"August 31st 2016",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:'
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\nVitamin K2 - Vital for Health and Wellbeing has been produced and distributed through the support from Kappa Bioscience, Norway.\n\n
',editors:[{id:"36345",title:"Prof.",name:"Jan",middleName:"Oxholm",surname:"Gordeladze",slug:"jan-gordeladze",fullName:"Jan Gordeladze",profilePictureURL:"https://mts.intechopen.com/storage/users/36345/images/3823_n.jpg",biography:"Dr. Jan O. Gordeladze, Ph.D. (born 25th of April, 1950), holds a triple professor competence (Medical Biochemistry, Physiology, and Pharmacology), and is presently working as a Professor Emeritus at the Department of Biochemistry, Institute of Basic Medical Science, University of Oslo, Norway. He has previously been employed as the Medical Director of MSD, Norway, serving two years as a Fulbright scholar at the NIH, Bethesda, Maryland, USA. From 2006-2009 he was employed as Associate Professor at the University of Montpellier, France. He is a member of the Norwegian Stem Cell Center, and his research has over the past 7-10 years been devoted to differentiation of osteochondral cells from stem cells focusing on the impact of transcription factors and microRNA species constituting regulatory loop interactions with functional target genes. He has published more than 120 scientific articles, reviews/book chapters and presented more than 250 abstracts/posters/talks at conferences worldwide. Dr. Gordeladze has served as a Fulbright Scholar at The National Institute of Health, Bethesda, Washington DC during the years 1990-91.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"9",totalChapterViews:"0",totalEditedBooks:"3",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"379",title:"Vitaminology",slug:"alimentology-vitaminology"}],chapters:[{id:"53889",title:"Introductory Chapter: Vitamin K2",doi:"10.5772/66384",slug:"introductory-chapter-vitamin-k2",totalDownloads:1770,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Jan Oxholm Gordeladze",downloadPdfUrl:"/chapter/pdf-download/53889",previewPdfUrl:"/chapter/pdf-preview/53889",authors:[{id:"36345",title:"Prof.",name:"Jan",surname:"Gordeladze",slug:"jan-gordeladze",fullName:"Jan Gordeladze"}],corrections:null},{id:"51057",title:"Vitamin K, SXR, and GGCX",doi:"10.5772/63983",slug:"vitamin-k-sxr-and-ggcx",totalDownloads:1792,totalCrossrefCites:0,totalDimensionsCites:3,hasAltmetrics:0,abstract:"Vitamin K was discovered in 1929 as a substance essential for blood coagulation and had been clinically utilized before the precise mechanism of action became aware in 1970s. The function as a cofactor of γ-glutamyl carboxylase (GGCX) was the mechanism firstly discovered with the identification of several substrate proteins including blood coagulation factors and osteocalcin. Recently, we and others have shown that vitamin K has other modes of function, such as ligand of nuclear receptor SXR (steroid and xenobiotic receptor) and its murine ortholog PXR (pregnane X receptor) and modulator of protein kinase A (PKA) activity. Besides its importance in blood coagulation, involvement of vitamin K has been shown in two major aging-related diseases, osteoporosis and osteoarthritis. Based on clinical and epidemiological studies, vitamin K is shown to have protective roles for both of them. Interestingly, clinical studies concerning single nucleotide polymorphisms (SNPs) of GGCX and γ-carboxylated status of osteocalcin suggested relationship between GGCX activity and bone-protective effect, while recent findings from basic research indicated that vitamin K functions mediated by SXR/PXR as well as GGCX are important in the bone metabolism. We also suggested that cartilage-protective effect is mediated by SXR/PXR signaling by animal experiments using Pxr knockout mice.",signatures:"Kotaro Azuma and Satoshi Inoue",downloadPdfUrl:"/chapter/pdf-download/51057",previewPdfUrl:"/chapter/pdf-preview/51057",authors:[{id:"184194",title:"Dr.",name:"Satoshi",surname:"Inoue",slug:"satoshi-inoue",fullName:"Satoshi Inoue"},{id:"189851",title:"Dr.",name:"Kotaro",surname:"Azuma",slug:"kotaro-azuma",fullName:"Kotaro Azuma"}],corrections:null},{id:"51024",title:"Vitamin K2 Rich Food Products",doi:"10.5772/63902",slug:"vitamin-k2-rich-food-products",totalDownloads:2067,totalCrossrefCites:2,totalDimensionsCites:2,hasAltmetrics:1,abstract:"Naturally, vitamin K exists in two bioactive forms mainly phylloquinone (vitamin K1) and menaquinones (vitamin K2). Phylloquinone is mostly found in green leafy vegetables such as kale, spinach, broccoli, and vegetable oils. However, menaquinones abundantly occurs in fermented vegetable products as menaquinones‐7 (MK‐7) and in animal‐based products as menaquinone‐4 (MK‐4). Diverse concentrations of menaquinones are present in various dietary sources such as fermented pulses and milk‐based products, cheese, meat, and animal organs. Presently, MK‐7 and MK‐4 contribute about 24 and 7%, respectively, of the total vitamin K dietary intake in the population consuming fermented products regularly. However, about 10% of menaquinones are pooled in the liver out of total intake of vitamin K. Conclusively, fermented soybean products and fermented milk‐based products such as cheese and soured milk contain ample amount of MK‐7, whereas animal organs, meat, fish, and egg contain appreciable amount of MK‐4.",signatures:"Muhammad Yasin, Masood Sadiq Butt and Aurang Zeb",downloadPdfUrl:"/chapter/pdf-download/51024",previewPdfUrl:"/chapter/pdf-preview/51024",authors:[{id:"178785",title:"Dr.",name:"Muhammad",surname:"Yasin",slug:"muhammad-yasin",fullName:"Muhammad Yasin"},{id:"182656",title:"Prof.",name:"Masood Sadiq",surname:"Butt",slug:"masood-sadiq-butt",fullName:"Masood Sadiq Butt"},{id:"189674",title:"Dr.",name:"Aurang",surname:"Zeb",slug:"aurang-zeb",fullName:"Aurang Zeb"}],corrections:null},{id:"50921",title:"Menaquinones, Bacteria, and Foods: Vitamin K2 in the Diet",doi:"10.5772/63712",slug:"menaquinones-bacteria-and-foods-vitamin-k2-in-the-diet",totalDownloads:3272,totalCrossrefCites:10,totalDimensionsCites:21,hasAltmetrics:1,abstract:"Vitamin K2 is a collection of isoprenologues that mostly originate from bacterial synthesis, also called menaquinones (MKs). Multiple bacterial species used as starter cultures for food fermentation are known to synthesize MK. Therefore, fermented food is the best source of vitamin K2. In the Western diet, dairy products are one of the best known and most commonly consumed group of fermented products.",signatures:"Barbara Walther and Magali Chollet",downloadPdfUrl:"/chapter/pdf-download/50921",previewPdfUrl:"/chapter/pdf-preview/50921",authors:[{id:"184784",title:"Dr.",name:"Barbara",surname:"Walther",slug:"barbara-walther",fullName:"Barbara Walther"},{id:"188194",title:"Mrs.",name:"Magali",surname:"Chollet",slug:"magali-chollet",fullName:"Magali Chollet"}],corrections:null},{id:"54263",title:"The Impact of Vitamin K2 on Energy Metabolism",doi:"10.5772/67152",slug:"the-impact-of-vitamin-k2-on-energy-metabolism",totalDownloads:1882,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Environmental and behavioral adaptations introduced during the last decades have synergistically enhanced man’s lifespan, but also paved the ground for disease states involving impairment of multiple organs, which are both modulating and depending on homeostatic calorie “accounting.”",signatures:"Mona Møller, Serena Tonstad, Tone Bathen and Jan Oxholm\nGordeladze",downloadPdfUrl:"/chapter/pdf-download/54263",previewPdfUrl:"/chapter/pdf-preview/54263",authors:[{id:"184157",title:"M.Sc.",name:"Mona",surname:"Møller",slug:"mona-moller",fullName:"Mona Møller"}],corrections:null},{id:"52078",title:"Vitamin K2 and Bone Health",doi:"10.5772/64876",slug:"vitamin-k2-and-bone-health",totalDownloads:2083,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"During the last 20 years, the main clinical effects of vitamin K2 on bone homeostasis have been investigated in both indirect and direct vitamin K treatment regimens. This chapter is mainly based on randomized clinical trials (RCT) lasting for more than 1 year. As for vitamin K1 (phylloquinone, indirect treatment) and vitamin K2 (menaquinone MK‐4 and MK‐7 direct treatment), respectively, the clinical trials have consistently shown decreased fracture rate incidents, however, mainly in Asian populations. In 2013, a major breakthrough was observed by Knapen et al. in the Netherlands, where menaquinone MK‐7 supplementation of 180 μg/day for 3 years to healthy postmenopausal women significantly decreased the age‐related decline in BMC (bone mineral contents) and BMD (bone mineral density) at the lumbar spine and femoral neck, but not at the total hip, as compared to placebo. Thus, MK‐7 supplementation has shown a significant “double”‐positive action through (1) increased bone building and (2) decreased bone resorption. We look forward to seeing the clinical effects on low bone mass and osteoporosis as well as other bone diseases.",signatures:"Niels Erik Frandsen and Jan Oxholm Gordeladze",downloadPdfUrl:"/chapter/pdf-download/52078",previewPdfUrl:"/chapter/pdf-preview/52078",authors:[{id:"186115",title:"M.D.",name:"Niels Erik",surname:"Frandsen",slug:"niels-erik-frandsen",fullName:"Niels Erik Frandsen"}],corrections:null},{id:"54291",title:"Vitamin K2 and its Impact on Tooth Epigenetics",doi:"10.5772/66383",slug:"vitamin-k2-and-its-impact-on-tooth-epigenetics",totalDownloads:2153,totalCrossrefCites:2,totalDimensionsCites:2,hasAltmetrics:1,abstract:"The impact of nutritional signals plays an important role in systemic-based «models» of dental caries. Present hypotheses now focus both on the oral environment and other organs, like the nervous system and brain. The tooth is subjected to shear forces, nourishing and cleansing, and its present “support system” (the hypothalamus/parotid axis) relays endocrine signaling to the parotid gland. Sugar consumption enhances hypothalamic oxidative stress (ROS), reversing dentinal fluid flow, thus creating an enhanced vulnerability to the oral bacterial flora. The acid, produced by the oral bacterial flora, then leads to erosion of the dentine, and an irreversible loss of dental enamel layers. This attack brings about inflammatory responses, yielding metalloproteinase-based “dissolution”. However, vitamin K2 (i.e. MK-4/MK-7) may come to the rescue with its antioxidant property, locally (mouth cavity) or systemically (via the brain), thus sustaining/preserving hormone-induced dentinal fluid flow (encompassing oxidative stress) and boosting/magnifying bodily inflammatory responses. However, sugars may also reduce the tooth’s natural defences through endocrine signaling, thus enhancing acid-supported enamel dentine erosion. Vitamin K2 sustains and improves the salivary buffering capacity via its impact on the secretion/flow of calcium and inorganic phosphates. Interestingly, primitive cultures’ diets (low-sugar and high-K2 diets) preserve dental health.",signatures:"Jan Oxholm Gordeladze, Maria A. Landin, Gaute Floer Johnsen,\nHåvard Jostein Haugen and Harald Osmundsen",downloadPdfUrl:"/chapter/pdf-download/54291",previewPdfUrl:"/chapter/pdf-preview/54291",authors:[{id:"36345",title:"Prof.",name:"Jan",surname:"Gordeladze",slug:"jan-gordeladze",fullName:"Jan Gordeladze"}],corrections:null},{id:"51205",title:"Anti-Inflammatory Actions of Vitamin K",doi:"10.5772/63891",slug:"anti-inflammatory-actions-of-vitamin-k",totalDownloads:2252,totalCrossrefCites:5,totalDimensionsCites:9,hasAltmetrics:1,abstract:"Naphthoquinone compounds have received attention for their ability to regulate diseases from bacterial and parasite infections through to chronic human diseases. Inflammation is widely considered to be at the root of many chronic diseases. The reports of anti-inflammatory activity of naphthoquinones, including vitamin K1 (phylloquinone) and vitamin K2s (menaquinones), are of interest due to their very low toxicity. Most of the evidence for the anti-inflammatory mechanisms of vitamin K suggests a role in the inhibition of the cell signalling complex nuclear factor kappa-B (NF-κB).",signatures:"Stephen J. Hodges, Andrew A. Pitsillides, Lars M. Ytrebø and Robin\nSoper",downloadPdfUrl:"/chapter/pdf-download/51205",previewPdfUrl:"/chapter/pdf-preview/51205",authors:[{id:"184368",title:"Dr.",name:"Stephen",surname:"Hodges",slug:"stephen-hodges",fullName:"Stephen Hodges"},{id:"184370",title:"Dr.",name:"Robin",surname:"Soper",slug:"robin-soper",fullName:"Robin Soper"},{id:"184371",title:"Prof.",name:"Andrew",surname:"Pitsillides",slug:"andrew-pitsillides",fullName:"Andrew Pitsillides"}],corrections:null},{id:"50916",title:"Vitamin K2: Implications for Cardiovascular Health in the Context of Plant-Based Diets, with Applications for Prostate Health",doi:"10.5772/63413",slug:"vitamin-k2-implications-for-cardiovascular-health-in-the-context-of-plant-based-diets-with-applicati",totalDownloads:3664,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Vitamin K was originally discovered as a blood coagulation factor. But observations regarding intakes in populations and health outcomes lead to a deeper understanding of the differences between vitamins K1 and K2. Studies of warfarin-treated rats and MGP -deficient mice led to understanding the central role of MGP in controlling calcification of arteries. A sensitive biomarker assay was then developed, based on a particular species of matrix γ–carboxylation protein OR matrix GLA protein (MGP). Warfarin therapy in people, especially those suffering from chronic kidney disease, was found to cause the highest level of this biomarker desphospho-uncarboxylated MGP (dp-ucMGP). Intervention studies with vitamin K2 brought down levels of dp-ucMGP and also led to relief of some disease endpoints. The process of varicose vein formation includes a role for vitamin K, implicating a lack of vitamin K in the development of varicoceles, which leads to benign prostate hyperplasia. It is likely that much good will be accomplished using vitamin K2 in interventions. Complex, multifaceted diseases will not be treated by single-nutrient solutions. The best interventions will be those which combine vitamin K2 treatment with a healthy diet rich in fruits and vegetables, combined with a healthy lifestyle.",signatures:"Michael S. Donaldson",downloadPdfUrl:"/chapter/pdf-download/50916",previewPdfUrl:"/chapter/pdf-preview/50916",authors:[{id:"180516",title:"Dr.",name:"Michael",surname:"Donaldson",slug:"michael-donaldson",fullName:"Michael Donaldson"}],corrections:null},{id:"50958",title:"Menaquinone‐4 Enhances Steroidogenesis in Testis Derived Tumor Cells Via the Elevation of cAMP Level",doi:"10.5772/63982",slug:"menaquinone-4-enhances-steroidogenesis-in-testis-derived-tumor-cells-via-the-elevation-of-camp-level",totalDownloads:1572,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Naturally existing vitamin K consists of vitamins K1 and K2. Menaquinone‐4 (MK‐4), an analog of vitamin K2 and a product of vitamin K1 metabolism, can be detected in several organs, including the testis; however, the function of MK‐4 in these tissues has not been well characterized. Recent studies have suggested that vitamin K is involved in enhancing protein kinase A (PKA) activity in several cell types, thus regulating numerous PKA‐dependent biological processes. To highlight the effect of vitamin K, we focused on its role in the steroidogenic pathway. Experiments on vitamin K–deficient rats revealed a reduced expression of genes involved in the biosynthesis of cholesterol and steroid hormones in the testis. Moreover, compared with control animals, rats fed on MK‐4 diet presented significantly higher testosterone levels in the plasma and testis. These results suggest that vitamin K is involved in the steroidogenic pathway in the testis. Testosterone levels were found to increase in a dose‐dependent manner also in cell‐based experiments upon addition of MK‐4, but such an effect was not observed in vitamin K1 levels. Furthermore, the effect of MK‐4 on testosterone production was abolished by the specific PKA inhibitor H89, thus confirming the regulatory role of MK‐4 on PKA activation. Here, we describe how MK‐4 modulates PKA activation by enhancing intracellular 3′,5′‐cyclic adenosine monophosphate (cAMP) levels in testis‐derived I‐10 cells. The presented evidence supports the role of MK‐4 in cAMP/PKA signaling and steroidogenesis.",signatures:"Hsin‐Jung Ho, Hitoshi Shirakawa and Michio Komai",downloadPdfUrl:"/chapter/pdf-download/50958",previewPdfUrl:"/chapter/pdf-preview/50958",authors:[{id:"180389",title:"Dr.",name:"Hitoshi",surname:"Shirakawa",slug:"hitoshi-shirakawa",fullName:"Hitoshi Shirakawa"},{id:"180489",title:"MSc.",name:"Hsin-Jung",surname:"Ho",slug:"hsin-jung-ho",fullName:"Hsin-Jung Ho"},{id:"180490",title:"Prof.",name:"Michio",surname:"Komai",slug:"michio-komai",fullName:"Michio Komai"}],corrections:null},{id:"54241",title:"Vitamin K2 Facilitating Inter-Organ Cross-Talk",doi:"10.5772/67153",slug:"vitamin-k2-facilitating-inter-organ-cross-talk",totalDownloads:1747,totalCrossrefCites:3,totalDimensionsCites:3,hasAltmetrics:1,abstract:"This chapter features how vitamin K2 is instrumental in bringing about inter-organ communication, thus facilitating (a) a synthesis/secretion of the endocrine, humoral factors from various organs and (b) physiological responses to the said factors by a multitude of organ systems of the body, thus creating a ‘lattice’ of reciprocal regulatory loops in order to ensure endocrine homeostasis.",signatures:"Jan O. Gordeladze, Håvard J. Haugen, Gaute Floer Johnsen and\nMona Møller",downloadPdfUrl:"/chapter/pdf-download/54241",previewPdfUrl:"/chapter/pdf-preview/54241",authors:[{id:"36345",title:"Prof.",name:"Jan",surname:"Gordeladze",slug:"jan-gordeladze",fullName:"Jan Gordeladze"}],corrections:null},{id:"51126",title:"Vitamin K2 in Animal Health: An Overview",doi:"10.5772/63901",slug:"vitamin-k2-in-animal-health-an-overview",totalDownloads:1748,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:1,abstract:"The role of vitamin K in animal health has not received much attention. Vitamin K studies have, for the most part, addressed the use of animals in the investigation of vitamin K physiology and pathophysiology, often using the rodent as a model system. However, vitamin K performs the same role in animals as it does in man and there are areas, such as animal nutrition, where a better understanding of animal requirements in general, and with ageing, could benefit animal health and continued well‐being.",signatures:"Jayde O’Neil, Bethany Scarrott, Ragnhild Aven Svalheim, Jonathan\nElliott and Stephen J. Hodges",downloadPdfUrl:"/chapter/pdf-download/51126",previewPdfUrl:"/chapter/pdf-preview/51126",authors:[{id:"184368",title:"Dr.",name:"Stephen",surname:"Hodges",slug:"stephen-hodges",fullName:"Stephen Hodges"},{id:"184369",title:"Ms.",name:"Jayde",surname:"O'Neil",slug:"jayde-o'neil",fullName:"Jayde O'Neil"},{id:"184748",title:"Ms.",name:"Bethany",surname:"Scarrott",slug:"bethany-scarrott",fullName:"Bethany Scarrott"},{id:"184749",title:"Prof.",name:"Jonathan",surname:"Elliott",slug:"jonathan-elliott",fullName:"Jonathan Elliott"},{id:"184750",title:"Ms.",name:"Ragnhild",surname:"Svalheim",slug:"ragnhild-svalheim",fullName:"Ragnhild Svalheim"}],corrections:null},{id:"50754",title:"Medicinal Chemistry of Vitamin K Derivatives and Metabolites",doi:"10.5772/63511",slug:"medicinal-chemistry-of-vitamin-k-derivatives-and-metabolites",totalDownloads:1876,totalCrossrefCites:2,totalDimensionsCites:2,hasAltmetrics:0,abstract:"Vitamin K acts as a cofactor for γ‐glutamyl carboxylase. Recently, various biological activities of vitamin K have been reported. Anti‐proliferative activities of vitamin K, especially in vitamin K3, are well known. In addition, various physiological and pharmacological functions of vitamin K2, such as transcription modulators as nuclear steroid and xenobiotic receptor (SXR) ligands and anti‐inflammatory effects, have been revealed in the past decade. Characterization of vitamin K metabolites is also important for clinical application of vitamin K and its derivatives. In this chapter, recent progress on the medicinal chemistry of vitamin K derivatives and metabolites is discussed.",signatures:"Shinya Fujii and Hiroyuki Kagechika",downloadPdfUrl:"/chapter/pdf-download/50754",previewPdfUrl:"/chapter/pdf-preview/50754",authors:[{id:"180528",title:"Dr.",name:"Hiroyuki",surname:"Kagechika",slug:"hiroyuki-kagechika",fullName:"Hiroyuki Kagechika"},{id:"180529",title:"Dr.",name:"Shinya",surname:"Fujii",slug:"shinya-fujii",fullName:"Shinya Fujii"}],corrections:null},{id:"50681",title:"From Protein Folding to Blood Coagulation: Menaquinone as a Metabolic Link between Bacteria and Mammals",doi:"10.5772/63342",slug:"from-protein-folding-to-blood-coagulation-menaquinone-as-a-metabolic-link-between-bacteria-and-mamma",totalDownloads:1894,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Menaquinones have long played a central role in bacterial metabolism due to their solubility in membranes and their ability to mediate electron transfer reactions between a large variety of enzymes. In addition to acting as important nodes in fermentation and respiration, menaquinones are critical to the formation of disulphide bonds in the periplasm. Their utility as molecular wires has also led to their incorporation into redox reactions in higher‐order organisms, where they participate in numerous physiological processes, including blood coagulation. Through studying the menaquinone‐dependent pathways in organisms across the phylogenetic spectrum, researchers have begun to uncover intriguing metabolic links and have identified novel compounds for modulating these vital pathways.",signatures:"Brian M. Meehan and Jonathan Beckwith",downloadPdfUrl:"/chapter/pdf-download/50681",previewPdfUrl:"/chapter/pdf-preview/50681",authors:[{id:"180269",title:"Dr.",name:"Brian",surname:"Meehan",slug:"brian-meehan",fullName:"Brian Meehan"},{id:"185054",title:"Prof.",name:"Jon",surname:"Beckwith",slug:"jon-beckwith",fullName:"Jon Beckwith"}],corrections:null},{id:"52618",title:"Vitamin K2 Biosynthesis: Drug Targets for New Antibacterials",doi:"10.5772/65487",slug:"vitamin-k2-biosynthesis-drug-targets-for-new-antibacterials",totalDownloads:2125,totalCrossrefCites:1,totalDimensionsCites:3,hasAltmetrics:0,abstract:"In prokaryotes, vitamin K2 (menaquinone) transfers two electrons in a process of aerobic or anaerobic respiration. Respiration occurs in the cell membrane of prokaryotic cells. Electron donors transfer two electrons to menaquinone (MK). Menaquinone in turn transfers these electrons to an electron acceptor. Menaquinones are vital for the electron transport chain. In the spectrum of Gram‐positive bacteria and Mycobacterium spp., vitamin K2 serves as the only quinone molecule in their electron shuffling systems. Hence, the bacterial enzymes associated with biosynthesis of the menaquinone(s) serve as potential target molecules for the development of new antibacterial drugs. This chapter summarizes the effects of vitamin K2 in bacteria and describes in more detail the aspects of menaquinone in bacterial electron transport in general, while also featuring the discoveries of menaquinone biosynthesis inhibitors.",signatures:"Michio Kurosu",downloadPdfUrl:"/chapter/pdf-download/52618",previewPdfUrl:"/chapter/pdf-preview/52618",authors:[{id:"33087",title:"Prof.",name:"Michio",surname:"Kurosu",slug:"michio-kurosu",fullName:"Michio Kurosu"}],corrections:null},{id:"50717",title:"Toxicological and Pharmacological Effects of VKOR Inhibitors",doi:"10.5772/63512",slug:"toxicological-and-pharmacological-effects-of-vkor-inhibitors",totalDownloads:1710,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Vitamin K1 2,3-epoxide reductase (VKOR) inhibition is the main pharmacological effect of warfarin, an anticoagulant that is typically used in the prevention of thrombosis and thromboembolism. The repeated oral administration of sodium dehydroacetate (DHA-S), which has been used as a food additive, preservative, and antimicrobial agent, induced severe hemorrhage in multiple organs and prolonged blood coagulation factors with VKOR inhibition in rats. On the other hand, VKOR and the vitamin K–dependent growth arrest–specific gene 6 (Gas6)/Axl pathway play a key role in mesangial cell proliferation in glomerulonephritis (GN). We herein indicated the potential of the VKOR inhibitor, 3-acetyl-5-methyltetronic acid (AMT), to prevent the proliferation of glomerular mesangial cells and suppress the progression of GN. DHA-S-induced hemorrhage was caused by the depletion of blood VK, associated with any factors including VKOR inhibition. The novel VKOR inhibitor, AMT, reduced renal mesangial cell proliferation and may be a supportive treatment for GN.",signatures:"Yohei Miyamoto",downloadPdfUrl:"/chapter/pdf-download/50717",previewPdfUrl:"/chapter/pdf-preview/50717",authors:[{id:"172105",title:"Ph.D.",name:"Yohei",surname:"Miyamoto",slug:"yohei-miyamoto",fullName:"Yohei Miyamoto"}],corrections:null},{id:"50994",title:"Enhanced Intracellular Delivery and Improved Antitumor Efficacy of Menaquinone-4",doi:"10.5772/63343",slug:"enhanced-intracellular-delivery-and-improved-antitumor-efficacy-of-menaquinone-4",totalDownloads:1513,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Hepatocellular carcinoma (HCC) is a major malignant tumor type that occurs globally. HCC incidence is increasing, especially in Asian countries. Despite many therapeutic approaches, the long-term prognosis of HCC remains poor because of frequent recurrence due to intrahepatic metastasis or multicentric carcinogenesis. Therefore, it is necessary to develop effective and safe chemopreventive agents to improve the prognosis of HCC. Menaquinone-4 (MK-4) has a suppressive effect on HCC, but cellular delivery is poor. We hypothesized that effective cellular delivery of menahydroquinone-4 (MKH), a fully reduced form of MK-4, would regulate HCC growth and metastasis. We developed a bioreductive activation-independent delivery system with the N,N-dimethylglycine ester of MKH (MKH-bis-DMG) to deliver MKH to HCC cells without any bioreductive processing of MK-4. MKH-bis-DMG inhibited the proliferation of both DCP-positive and DCP-negative HCC cell lines in a time- and dose-dependent manner via G1/S cell-cycle arrest. We assessed the effect of MKH-derivatives on HCC metastasis using a mouse model of spleen-liver metastasis. The mean tumor hepatic replacement area of MKH-bis-DMG treated mice was significantly less than that of untreated mice. 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Introduction
Black Lives Matter is an antiracist social movement which first emerged in the US in 2013, with the use of the hashtag # BlackLivesMatter. The trigger for the emergence of this movement was the exasperation felt by many over the acquittal of George Zimmerman for shooting dead an unarmed black teenager, Trayvon Martin in 2012. While the movement spead beyond the US in subsequent years, with one first emerging in the UK in 2016, what reignited and indeed popularized this movement, and transformed it into a global phenomenon, was the murder (caught on video) of George Floyd at the hands of a Minneapolis police officer, Derek Chauvin in May 2020. Floyd’s murder prompted widespread demonstrations in solidarity with victims of racial injustice across the world. In the UK, this entailed protests across the country and in one instance in Bristol the toppling of the statue of a slave trader, Edward Colston and throwing him into the harbor. A national conversation ensued with renewed reflection by a number of cultural institutions about their historic role in colonialism and slavery, increasing numbers of corporations signing up to the Business in the Community Race at Work Charter, and sports teams, especially in football following the precedent first set by Colin Kapernick of the NFL in 2016 and taking a knee in protest at racism and police brutality. The conversation was inevitably a heated one, with vehement criticism of ‘baying mobs’, ‘virtue signaling’ organizations and booing of footballers taking a knee. The UK government had to respond and in June 2020 announced the creation of a Commission on Race and Ethnic Disparities. The commission chaired by Tony Sewell produced its report in March 2021, but the report proved just as contentious and polarization has persisted.
I am concerned in this chapter to demonstrate that an anti-political correctness (or anti-woke) discourse is critical to understanding the backlash to the Black Lives Matter movement evident in the UK. This is therefore a ‘perspective’ chapter which does not purport to generate new primary data but rather to provide a narrative that draws on secondary data to explore the role of the state, the media and other actors in the reproduction of structural racism. Right wing media have routinely drawn upon an anti-PC discourse to discredit antiracism and other social justice initiatives and the advent of a populist Conservative government, all too ready to demonstrate its anti-PC credentials through its ‘war on woke,’ helps to reinforce the hegemony of this discourse. In the first part of this chapter, I shall seek to demonstrate the pervasiveness of this discourse and the way the government has sought to mount its anti-woke agenda. In the second part of the chapter, I shall summarize and critique the Sewell report, arguing that the report itself is consonant with the government’s anti-woke agenda and does not therefore challenge structural racism.
2. Political correctness and the anti-woke agenda
Although we are continually being reminded that we live in a world where political correctness (or its surrogate wokeism) is pervasive, the concept itself remains unclear and indeed contested. A few writers embrace the term to signal their belief in the importance of being inclusive [1]. More commonly, however, the term is used in a disparaging way to mock what is seen as a ludicrous attempt to avoid the real issues or warn us of the dangerous new culture threatening free speech and plain honest speaking. In the process a contrast is often drawn between political correctness and commonsense: ‘Voters seek return to common sense in revolt against political correctness’ announces a not untypical headline in one broadsheet [2].
The invocation of the common refrain, PC gone mad serves to link the positive and negative usages of the concept together in a revealing way. A narrative is constructed which suggests that at one stage PC was indeed progressive in promoting social justice for minorities but that it has gone too far so that now ‘people are becoming frightened of saying the wrong thing, using the wrong language about a pretty wide range of opinion’ [3]. This view is widely shared: ‘The progressive movement, that has done so much to tackle inequality and unfairness, has been captured by ultras who demand absolute conformity with every article of their faith’ [4]. Another journalist, further right on the political spectrum, concurs. The decline of religion and subsequently secular ideologies has left a vacuum which has been filled by social justice zealots. Failing to acknowledge the success of previous human rights campaigns in righting historical injustices relating to race, gender and sexuality, new theories emerged ‘to suggest that things had never been worse. Suddenly - after most of us had hope it had become a non-issue – everything seemed to have become about race’. A crusading desire to right perceived wrongs has entailed the creation of ‘a set of tripwires laid across the culture…What everyone does know are the things that people will be called if their foot ever nicks against these freshly laid tripwires. “Bigot”, “homophobe”, “sexist”, “mysognist”, “racist” and “transphobe” are just for starters’ [5].
There is little doubt that political correctness (and wokeism) now typically carries negative connotations. Few people consequently identify themselves as supportive of PC and when they do, they sound on the defensive [1]. More typically, those who are sympathetic to the causes associated with PC will studiously avoid defining themselves as advocates of PC. The same is also true of a related concept, ‘woke’ which, though initially coined to refer to awareness of racial injustice ‘has been weaponised’ by the right wing media and subsequently used in a derogatory fashion [6]. Here are two examples: ‘The woke left is the new Ministry of Truth…Good people are silenced in an Orwellian nightmare where a tyrannical minority decide what we’re allowed to say [7]. And ‘The march of wokeism is an all-pervasive new oppression’ [8].
Althoigh media references to political correctness and woke are widespread, these and related terms such as cancel culture are rarely defined. Instead they are used to depict the Other in a disparaging way and often to suggest that there are powerful forces suppressing inconvenient truths and steadily eroding our freedom. One broadcaster believes that we need to wake up before it’s too late: ‘We’ve become a timid, mute, fearful society in which everyone must walk on constant eggshells for fear that they will be next for the social media pile-on and politically correct execution’ [9].
This characterization of PC and woke is highly influential and clearly resonates with many people. One survey in 2020 CSS found ‘six in ten’ agreeing ‘that political correctness gives “too much power to a small minority of people who like to take offence”, with nearly eight in ten agreeing ‘that “you have to walk on eggshells when speaking about certain issues these days” and over eight in ten agreeing ‘that “too many people are easily offended these days”’ ([2]; see also [10]). The media in short portray political correctness in a derogatory fashion and most people buy into this picture.
We should note that the attack on PC is often part of a sustained campaign waged by conservatives and integral to the culture wars they believe play well with many people [11]. In the UK the right-wing press has waged a long campaign against PC (or its surrogates such as wokeness and cancel culture) which has provided fertile ground for Boris Johnson’s brand of populism and helped contribute to the decision for Britain to leave the European Union (Brexit).
Boris Johnson as both a right-wing journalist and politician has not been averse to speak disparagingly of people of color, and indeed extolling political incorrectness. My central concern here, however, is with his response as Prime Minister to Black Lives Matter (BLM). Nigel Farage, a central figure in the Brexit campaign, was highly critical from the start of a movement he castigated as a threat to the British way of life. He prodded Johnson: ‘I’m afraid Boris Johnson and the government have gone along with this PC woke agenda’ (Farage quoted in [12]). Provoked by Farage, Johnson used a Conservative conference speech to nail his mast to the wind: ‘We are proud of this country’s culture and history and traditions; they [Labour] literally want to pull statues down, to rewrite the history of our country, to edit our national CV to make it look more politically correct’ (Johnson quoted in [11]).
This speech is part of a wider campaign waged by the right-wing press and increasingly by the government against PC [13]. The ‘war on woke’ entails identifying different threats to our way of life and lampooning institutions for their virtue signaling capitulation to PC [14, 15]. One example relates to the initial decision of the BBC to perform an orchestral rather than choral version of two patriotic songs at the Last night of the Proms: ‘Right-wing newspapers seized on the story…with the Sun running the story under the headline “Land of woke and glory”. They saw the lack of singing as a surrender – not a practical decision that reflected the difficulties of putting on a prom during a pandemic. Cue the intervention of the prime minister: “I think it’s time we stopped our cringing embarrassment about our history, about our traditions, and about our culture and we stopped this general fight of self-recrimination and wetness” (Johnson quoted in [16]).
In some cases, there have been veiled threats of funding cuts and proposed new laws. The Culture Secretary announced to museums and funding bodies: ‘The government does not support the removal of statues or other similar objects…You should not be taking actions motivated by activism or politics’ (Dowden quoted in [17]). The Communities Secretary has subsequently proposed new laws to protect ‘statues, plaques, memorials or monuments…from being removed “at the hands of the flash mob, or by the decree of…town hall militants and woke worthies”’ (Jenrick quoted in [18]). Meanwhile the Education Secretary summarily dismissed calls for changes to the history curriculum in schools to incorporate Britain’s colonial past and involvement in slavery: ‘We have an incredibly rich history, and we should be incredibly proud of our history because time and time again, this country has made a difference and changed things for the better, right around the world’ (Williamson quoted in [19]). At the same time he has introduced new legislation on free speech ‘to counter what he called “unacceptable silencing and censoring” on campuses, despite the paucity of evidence of ‘no platforming’ and repeated reference to a key example of silencing and censoring when in fact ‘the event went ahead’ [20].
A particularly revealing intervention has come from the Minister for women and equalities in a speech where she set out a new approach to equality ‘based on “Conservative values”…and ‘pledged that equality will now be “about individual dignity and humanity, not quotas and targets, or equality of outcome”’. The UK had focused too much on ‘fashionable’ race, sexuality and gender issues: We will not limit our fight for fairness to the nine protected characteristics laid out in the 2010 Equality Act, which includes sex, race and gender reassignment…the focus on protected characteristics has led to a narrowing of equality debate that overlooks socioeconomic status and geographic inequality. This means some issues – particularly those facing white working class children – are neglected (Truss quoted in [21]).
In a year when we had become more aware of racial injustice and ethnic disparities in outcomes, the Minister seemed be ‘play[ing] to the culture wars gallery and to be pitting the needs of minorities against those of the working class, when neither of them have been properly addressed’ [22]. Challenged about this, ‘Home Secretary Priti Patel [who described the Black Lives Matter protests as “dreadful”] backed Ms Truss’s plans: “We’re focusing on the people’s priorities – we shouldn’t be indulging in fashionable issues of political correctness”’ [23].
In all the cases mentioned above, Ministers of Departments, including the Prime Minister, have played a role in undermining a movement concerned to combat structural racism. While there may be divisions within the government, no Ministers have publicly challenged the anti-woke agenda trumpeted in these six cases, let alone exhibited sympathy towards an anti-racist movement or advocated any concrete measures to eradicate racial disparities. The government has instead intervened to subvert the fight against structural racism [13, 24].
In the US the attacks on PC have clearly been orchestrated. ‘Most of the conservative books and articles…repeat the same stories, use the same terms and [are] largely funded by bodies known to have right-wing leanings’ [25]. And, not surprisingly in a global world, something like that is evident now in the UK, with the recycling of the same themes, the same examples and indeed the same purported intellectual roots in postmodernism/cultural Marxism. The examples are typically ‘exaggerated or fabricated in some way’ [25]. Famous examples in an earlier period include the story that ‘local councils in London had banned black coffee and black bin liners on the grounds that they were racist’ [25] and the story that you could no longer celebrate Christmas in Birmingham because the city council had replaced it with Winterval, a story the Daily Mail later acknowledged to be false in 2011. On examination ‘almost all claims that “political correctness has gone mad” turn out to be based on hokum and hot air’ ([26]: see [2] for for further examples). This unfortunately does not mean that they are not believed even years after first being aired. The campaign ‘by the conservative right in the US [has been] very successful’ in creating a PC bogeyman and stigmatizing the Left [25] and there is evidence that it is making significant headway in the UK [27].
A recent book which expressly looks at culture wars as they are playing out in the UK is very revealing in this context. The authors argue that ‘culture war issues are those concerned with identity, values and culture which are vulnerable to being weaponised by those concerned with engaging and enraging people on an emotional level’ [27]. In contrast to the US where ‘groups split the same way on issue after issue’ the UK witnesses a much broader consensus on many of ‘the issues which most polarize the US, including climate change, gender equality and racial justice’ [[27]; see also [10]]. One might have anticipated therefore that the UK would have avoided the culture wars waging in the US. This is not the case, however. ‘There has been a huge surge in media coverage mentioning “culture wars”…and since 2016 coverage of the UK culture wars has taken off’ [28]. The major driver for this is a political calculation: for key Conservative party strategists, ‘the culture wars playbook is an indispensable part of holding together their winning electoral coalition post-Brexit’ [27]. It seeks to demonstrates to working class voters in northern England who voted Conservative for the first at the last election that the government sees the world as they do and it seeks to tempt the Labour opposition to challenge them on territory of their choosing [6]. And all the while the media fans the flames, incentivized by their algorithms to pursue contentious stories.
Three main criteria indicate that we are witnessing a cultural wars issue: a group is represented as undermining order and tradition; we are depicted as losing out to the Other; and the issue is being blown out of all proportion.
An example of the first criterion is the attack on museums and the most popular heritage body in the UK, the National Trust for having the temerity to reveal their historical links to colonialism and slavery. The ensuing rows feed into a new political battle ground, with ‘government ministers positioning themselves as “defenders” of history and the nations’s pride’, thus framing attempt to reconsider museum collections and ‘expand the historical records as “attacks” on history and by implication, the nation and its people’ [27].
An example of the second criterion of a culture wars issue is the attack on the concept of ‘white privilege’, a concept coined to point to the fact that White people, by virtue of being White do not have to deal with racism [29]. Racism is exemplified by the massively disproportionate use of stop and search on Black people relative to White people and is illustrated graphically in the experience of Bianca Williams, the British sprinter who was handcuffed during a stop and search operation in July 2020. Kemi Badenoch, Equalities Minister criticized the concept in Parliament in October 2020: ‘We do not want to see teachers teaching their white pupils about white privilege and inherited racial guilt’. And the same refrain was evident in the Conservative dominated education report in June 2021 which claimed that white privilege may have contributed towards the systematic neglect of white working class pupils. The report juxtaposes poor white pupils and poor racialised pupils, and thus pits different groups against each other. This example constitutes ‘the latest step in an ongoing campaign to use the underachievement of poor white people as a weapon to demonise antiracism and keep the same people angry at the wrong target’ [30].
A recent example of the third criterion of a culture wars issue is the condemnation of the decision by students at Magdalen College, Oxford to remove a portrait of the Queen from their middle common room. The Education Secretary branded the move absurd: ‘Oxford University students removing a picture of the Queen is simply absurd. She is Head of State and a symbol of what is best about the UK. During her long reign she has worked tirelessly to promote British values of tolerance, inclusivity and respect around the world’ (Williamson quoted in [31]). In the same week, the Culture Secretary also had recourse to Twitter, arguing that the decision of the English Cricket Board to suspend an English cricketer for a series of racist and sexist tweets when he was 18 was over the top. And the Home Secretary, initially supported by the Prime Minister, dismissed the decision by the England football team to take a knee during the Euros as ‘gesture politics’ and refused to condemn a section of the crowd for booing the team when they did take a knee [32].
The consequences of culture wars are disturbing in three ways. Firstly, they distract attention from substantive issues. The Black lives movement highlighted the importance of addressing structural racism, but the impact of stories about Rule Britannia being played but not sung at the Proms and pulling down historical monuments with racist links ‘is to reframe the whole Black Lives Matter movement as being primarily about issues like this, leaving the casual observer thinking “all these street protests because you don’t like old songs or statues?”’ [27]. Secondly culture wars are divisive, stoking the idea that if a minority benefit, the majority must lose out. This is evident when for example the interests of minority ethnic groups and the white working class are deemed to be divergent. Thirdly culture wars produce an increasingly toxic public sphere, demoralizing people pushing, say, for racial justice. And they can backfire, with the comments of senior politicians arguably facilitating the racist abuse Black footballers faced after England lost in the final of the Euros. A senior Conservative politician puts it well: ‘If we whistle and the dog reacts, we can’t be shocked if it barks and bites. Dog whistles win votes but destroy nations…It shames me that in 2021 some in politics are still playing fast and loose with issues of race’ (Warsi quoted in [33]).
3. Changing the narrative: the Sewell report
The confluence of widespread support for Black Lives Matter and the evident ethnic disparities in Covid-19 related mortality in a pandemic propelled Boris Johnson as Prime Minister to announce the setting up of a Commission on racial and ethnic disparities in June 2020. ‘It was no use just saying that we have made huge progress in tackling racism…There is much more we need to do…We have to look at discrimination but what has slightly been lost in this is the story of success…What I want to do as prime minister is change the narrative so we stop the sense of victimhood and discrimination…and we start to have a real expectation of success’ (Johnson, my emphasis, quoted in [34]). A month later, the membership was announced, with Tony Sewell as Chair and all the commissioners bar one being from an Asian, African or Caribbean background. The Commission was enjoined to inform a national conversation on race led by the evidence and building on the Race disparity audit launched in 2016. The key objectives were to identify persistent disparities in four priority areas, notably education, employment, criminal justice and health; to provide explanations for such persistent disparities; and to make appropriate recommendations to address them. The commission was asked to produce its report by the end of the year.
The decision to set up the Commission was greeted by many antiracists with skepticism, given the plethora of previous race inquiries, including seven since 2010, and ‘no fewer than 200 unimplemented recommendations made by reports ordered by the Government’ [35]. This disquiet was magnified by the fact that Munira Mirza, Head of the No 10 policy unit was placed in charge of organizing the commission and Tony Sewell was subsequently asked to be Chair. Both were on record as skeptical of racism, as a causal factor for ethnic disparities generally [36] and education in particular [37]. Particular venom was expressed towards the concept of institutional racism, which in their eyes has become the ‘new orthodoxy’ [36] and for which the ‘evidence…is flimsy’ [37] but whose pervasiveness has ‘corroded BAME communities’ trust in public services’ [36] and resulted in some of them inculcating ‘the discourse of the victim’ [37]. It is revealing as we shall see that the positions adopted earlier by Mirza and Sewell are not only consonant with those of Johnson but also permeate the final report. The latter eventually saw the light of day at the end of March 2021.
The tone of the report [38] is set in the foreword written by the Chair. ‘Put simply we no longer see a Britain where the system is deliberately rigged against ethnic minorities. The impediments and disparities do exist, they are varied, and ironically very few of them are directly to do with racism…The evidence shows that geography, family influence, socio-economic background, culture and religion have more significant impact on life chances than the existence of racism’. Indeed it needs to be recognized that some White groups are also faring badly. While it is acknowledged that ‘racism’ is still ‘a real force in the UK, all too often ‘historic experience of racism still haunts the present’ and this perception inhibits acknowledgement ‘that the UK [has] become open and fairer’, with the data pointing in fact to ‘many instances of success among minority communities…An unexplored approach to closing disparity gaps [is] to examine the extent individuals and their communities [can] help themselves through their own agency, rather than wait for invisible external forces to assemble to do the job’. It is crucial in this context that we do not use concepts such as institutional racism loosely and in the process generate among members of minority communities ‘a fatalistic narrative that says the deck is permanently stacked against them’. Although ‘the UK is open to all its communities…the door may be only half open to some, including the White working class’. The report hence makes a number of recommendations in each of the priority areas examined in the report. These include measures to encourage the police to be ‘a more welcoming organization and Black communities…to overcome the legacy of mistrust’; and the creation of a ‘new Office for Health Disparities…to respond to the specific health and wellbeing of ethnic groups’. In education, ‘the “Making of Modern Britain” teaching resource, is [the] response to negative calls for “decolonizing” the curriculum. Neither the banning of White authors or token expressions of Black achievement will help to broaden young minds’. Rather than ‘bringing down statues’ it is important that ‘all children reclaim their British heritage’. In employment, it is important that measures are adopted which ‘foster talent from a wide range of backgrounds’ rather than engage in virtue signaling measures targeted at White people such as “unconscious bias” training’. Conscious of the fact that different communities have very different experiences, it is also argued that the term BAME (Black, Asian and minority ethnic) has past its sell date. Implementation of these (and other) recommendations ‘will give a further burst of momentum to the story of our country’s progress to a successful multicultural community – a beacon to the rest of Europe and the world’.
The introduction reinforces the themes outlined in the foreword. We do not live in a post-racial society. Racism still exists but we have come a long way as the success of ethnic minorities in education and to a lesser extent employment testifies. In addition, the roots of disadvantage are complex and as much to do with social class, family culture and geography as ethnicity. Indeed, the disparities found often do not have their origins in racism, a concept that has become inflated. Contrary to ‘an increasingly strident form of anti-racism that seeks to explain all minority disadvantage through the prism of White discrimination’, minority success and failure is often nothing to do with discrimination but stems instead from the cultures and attitudes of minorities, especially ‘family life and structure’. The report seeks to be balanced, paying attention to minority successes in say overall health as well as the impediments to full participation. On this basis, it makes 24 recommendations around 4 themes (building trust; promoting fairness; creating agency; and achieving inclusivity) to address disparities.
‘BLM marches’ the report argues sought change in the UK as well as the US, but the narrative of many young people, focused on the belief that ‘nothing has changed for the better’ as a result of ‘institutional racism and White privilege’, alienates ‘the decent centre ground…The big challenge of our age is not overt racial prejudice. It is building on and advancing the progress won by the struggles of the past 50 years…The more recent instances where minority communities have felt rightly let down’ such as ‘the Grenfel tragedy or the Windrush scandal’ or ‘the disproportionate impact of COVID-19’ did ‘not come about because of design, and [were] certainly not deliberately targeted. We are as a society more open than 50 years ago, as the evidence of a commissioned study of social mobility [39] demonstrates. This study indicates that ‘ethnic minority children with parents in routine manual jobs were much more likely to achieve upward mobility compared with their White peers’ and that in spite of variations, ‘there have have been more signs of social progress than regress…with some groups, like those from the Indian and Chinese ethnic groups doing even better than the White ethnic group, and other groups catching up’. We need therefore to look beyond race, especially given that in education, ‘White working class children trail behind their peers in almost all ethnic minority groups’.
‘Overt and outright racism’ still persists and is particularly severe in social media. We should be careful, however, not to be swayed by overly ‘pessimistic narratives about race’ generated by the ‘rise of identity politics’, which is in turn characterized by lobby groups with ‘a pessimism bias’ who highlight lived experience rather than objective reality: hate crime is not in fact rising; and higher mortality from COVID-19 is not a function of racism but socio-economic status and other factors. Ethnic minorities clearly are able to overcome obstacles and achieve success as is evident in a commissioned study on educational achievement [40]. This study demonstrates ‘that attainment is closely related to socio-economic status – once this is controlled for, all major ethnic groups perform better than White British pupils except for Black Caribbean pupils”. There are significant differences, however, between minority groups and this means that the concept of BAME ‘is no longer helpful’ and we need a more nuanced approach. The same goes with the language of race and racism. There is a tendency to conflate discrimination and disparities and to employ racism (especially institutional racism) in an inflated way. Macpherson’s definition of institutional racism which points to processes within orgaisations that have a discriminatory impact, the report argues, ‘has stood the test of time’ but ‘given that reporting hate crime and race-related incidents is now largely encouraged by police forces…and ‘there is much greater awareness and willingness to record and monitor such incidents’, the police can no longer be characterized, as the MacPherson report [41] did in 1999, in these terms. The perception that racism is increasing is facilitated by social media and is not helped by ‘the subjective definition of a racist incident…To limit the widening charge of racism’ we should assess ‘the intent of the perpetrator as well as the perception of the victim’. We also need clear definitions of different kinds of racism and distinguish different ‘forms of racial disparity’: explained (by other ‘factors such as geography, class or sex’) and unexplained racial disparities. We need to dispense with the notion of white privilege (as opposed to affinity bias) because it ‘fails to identify the real causes of disparities, and…is divisive’. Nonetheless racism persists and the report recommends strengthening the Equality and Human Rights Commission with additional resources to drive it out.
The UK suffers from ‘acute geographical inequality’ which ‘in simple numerical terms’ (but not proportionate terms) is ‘overwhelmingly a White British problem’. This reinforces the Commission’s view that ‘its recommendations should focus on improving outcomes for all - not centre on specific ethnic groups alone’. Nonetheless ‘racial disadvantage often overlaps with social class disadvantage’, with ‘people from minority communities…more likely to live in households with persistent low income’. Some groups have ‘transcended that disadvantage more swiftly than others’, with Indian and Chinese ethnic groups being significantly more successful than Black Caribbean and Pakistani/Bangladeshi ethnic groups. The commission identifies two factors which militate against success: family breakdown and limited cultural integration. Family breakdown is higher among Black Caribbeans and a lack of cultural integration is evident among Pakistani/Bangladeshis who tend to abide by different social norms, especially in relation to gender, with low economic activity and lack of English speaking among women evident. The commission is adamant that this is not about allocating blame.
When it comes to what we think about race, the Commission, while recognizing the continuing presence of discrimination, is optimistic both in the direction of travel and by comparison with other countries. What is crucial is that ‘we respect ethnic identities but also share a common, unifying, civic identity as British citizens’.
The four chapters focused on education, employment, crime and policing, and health cover a lot of detailed ground. My summary of these chapters perforce will need to be selective and below I shall focus on those parts which have not been mentioned earlier.
The education chapter focuses predominantly on schooling but does briefly allude to higher education. ‘Most ethnic minorities do relatively well in accessing higher education, including those from lower socio-economic backgrounds’ with ‘White students…the least likely to go to university’. At the same time, the report acknowledges that students from the minority groups are less likely than their White peers ‘to ‘progress to the more elite high tariff universities’ and that ‘once at university ethnic minority students -with the exception of Asian students – are more likely to drop out, have lower levels of attainment, and lower earnings after graduation’. In the light of this, the Commission recommends better careers advice and ‘stronger guidance from the ‘Office for Students’.
The employment chapter argues that ‘there has been a gradual convergence on the White average in employment, pay and entry to the middle class, with some groups overtaking the White majority and others somewhat underperforming’. The picture is not quite as bright when it comes to advancement ‘into the very top positions in professional, business and public life’. It is acknowledged that ‘bias, at least in hiring, exists as ‘job application field experiments…carried out in the UK since the late 1960s’ demonstrate. The report warns us, however, to be circumspect: ‘We know that discrimination occurs, but these field experiments cannot be relied upon to provide clarity on the extent that it happens in everyday life’. Varying promotion rates may also signify discrimination. Certainly ‘there is a perception that people at the top tend to have affinity bias, appointing people in their own image’. We are all prone to affinity bias but the bias of those who ‘tend to dominate the top positions…matters more…Many companies have been prompted into intense soul-searching with regard to race, prompted by the Black Lives Matter movement. They have adopted various diversity and inclusion [initiatives]’. Unfortunately, ‘most researchers remain sceptical about the impact of unconscious bias training, quotas and diversity specialists’. The answer is certainly not unconscious bias training, which is counterproductive, discriminatory and ‘alienating’. Far more useful are ‘“nudge”-style procedures’.
The crime and policing chapter expends considerable energy examining the ‘disparities in rates of stop and search between Black and White people’. In the Commission’s view, these disparities need to be placed in the context of ‘disparities in crime, and often violent crime, that lie behind stop and search’. We need ‘to acknowledge other factors, in addition to racism, when considering disproportionality’ especially given that ‘great strides have been made towards becoming a service that can fairly police a multi-ethnic society’. There is a mismatch between government and police narratives over the drivers for the use of stop and search, with knife crime highlighted by politicians and drug offenses by the police. While there are indeed significant national disparities in stop and search, they need to be analyzed at ‘smaller geographic areas’ with ‘relatively high crime rates where stop and search is used more’. Both the communities and the police need to take action; there need to be ‘community based initiatives to divert young people away from criminal activity’, but at the same time the police need to ensure that stop and search is ‘used fairly and properly’ to prevent encounters with a few ‘rogue elements within [the police]’ reinforcing historical mistrust generated by ‘unfair and excessive policing in the past’. In addition to disproportionality in stop and search, there is also evidence of disproportionality in the use of restraint, sometimes with tragic consequences. While we cannot be sure ‘that racism was a factor in deaths in police custody’, there needs to be increased ‘training in de-escalation techniques’ and more monitoring by senior officers. In addition, the legitimacy and accountability of stop and search need to be reinforced through the use of body worn video. And there needs to be a more uniform approach to promote transparency, community involvement and scrutiny. There is also in the Commission’s view ‘a case for treating low-level class B drug possession through alternative pathways outside of the criminal justice system’. While progress has been made in creating ‘a more diverse police force…policing remains a cold spot, especially at the top’. This is partly because ‘police from ethnic minority backgrounds’ often experience ‘shocking abuse’ from ‘other ethnic minority citizens in the communities they serve’. The commission found ‘no available data on charges of racism in the police workforce’ though it does mention ‘significant differences between White and ethnic minority officers in the amount of internal conduct allegations and the severity assessments made by professional standards departments’. Despite the progress towards a more diverse workforce, the Commission nonetheless acknowledges that ‘progress remains frustratingly slow’.
The health chapter argues that for many key health outcomes, ‘ethnic minority groups have better outcomes than the White populations…Ethnicity is not the major driver of health inequalities’. Although the evidence is that deprivation, geography and differential exposure to key risk factors are far more important, it is acknowledged that we need further research to understand differences between ethnic groups, given that this was beyond the remit of the major review of health inequalities, the Marmot review. It is acknowledged that there are significant ethnic disparities in mortality arising from COVID-19, but it is stressed that this is ‘driven by risk of infection’, occasioned by living in densely populated areas/households and comorbidities, ‘as opposed to ethnicity alone being a risk’. Unlike other reports, the Commission found ‘no overwhelming evidence of racism in the treatment of and diagnosis of mental health conditions’. There is disparity in community treatment orders and detention, but this is not necessarily evidence of racism since there is a difference in the prevalence of mental illness, though albeit a key risk factor here is racism.
The conclusion to the report stresses that we should abandon ‘the old idea of BAME versus White Britain’ and be optimistic. Yes, there are disparities but they are not always negative and cannot be understood purely in terms of ‘race based discrimination’ We need also to consider ‘the role of cultural traditions’ and social class, and recognize the importance of agency. The BLM movement has put the race issues back on the agenda, but we should not be fatalistic, accentuate differences and offer solutions based on the binary divides of the past. Instead we should be infused with the spirit of British optimism, fairness and national purpose that was captured by that 2012 Olympic opening ceremony, and has animated this report’.
4. Challenging the narrative
The report purports to be balanced and provide an evidence-based contribution to the national conversation over race inspired by the Black Lives Matter movement. And there is indeed much of merit in the report which is consonant with the academic literature in this field:
Britain is characterized by ‘racial disadvantage and ethnic diversity’ [42]. Minority ethnic groups continue to face some common disadvantages in comparison to the majority ethnic group, partly because of racial discrimination (racial disadvantage) but at the same time there is considerable diversity in the socio-economic position of different minority ethnic groups (ethnic diversity).
Racism persists and has a significant impact on individuals and families in minority communities.
We cannot assume that racial disadvantage/ethnic disparities stem from racism or racial discrimination, but need to examine the evidence carefully and employ key concepts in an analytical way.
There is considerable evidence that minority ethnic groups have made considerable strides in education and to some extent in employment.
We need to recognize the agency of minority ethnic groups who continue to invest in education and draw on the cultural capital of their own communities to resist discriminatory practices and thus improve their situation.
Britain has been less reluctant than many other countries to collect data on people’s ethnic identity and has been at the forefront in Europe in developing anti-discrimination/equality legislation.
Further measures need to be taken for Britain to become a vibrant multi-cultural society which strikes an appropriate balance between the need to treat people equally, to respect different ethnic identities, and maintain shared values and social cohesion.
Despite these merits, any hopes that the report would shift the national conversation away from ‘culture wars’ towards a balanced informed discussion about race were quickly dashed, with the same antagonists in the culture wars at each other’s throats again. The resignation on the day of publication of No 10’s race advisor, Samuel Kasumu, who had earlier expressed dismay at the government for pursuing a ‘politics steeped in division’, was an early portent. Some commentators welcomed the report seeing it as a powerful challenge to ‘the pessimistic identity-politics-based race narrative that has become so influential in recent years’ [43], but most were highly critical, with one journalist describing the report as ‘shoddy…littered with mistakes and outright mangling of sources, alongside…selective quoting’ [44] and one academic describing it as ‘poisonously patronizing’ and ‘historically illiterate’ [45].
What is evident when we examine the report is that the central thrust of its narrative has an ‘optimism bias’, which, while recognizing racism and racial discrimination, tends to downplay their prevalence (as evidenced in attitude surveys and field experiments), significance (as illustrated not only by racist abuse but also micro-aggressions) and systematic nature (with organizations across the board producing unequal outcomes). There is some justification in seeing education as a success story, but the world of work is another matter. Here the report’s optimism bias glosses over what is for many members of minority communities a difficult transition. Field experiments clearly demonstrate racial discrimination in the labour market. Such discrimination is associated with ethnic penalties, but the latter varies by group, with some groups having more resourceful social networks so that they are able to be relatively successful in spite of discrimination [46]. Investment in educational pays off, but the return for minorities is less than that for their White peers. Ethnic minority graduates are much less likely to be employed than their White peers six months after graduation, even after controlling for class and education, and an earnings gap apparent in the early career of British graduates persists long after graduation [47]. Ethnic pay gaps are in fact large and stable once suitable controls are put in place, and it’s by no means clear that things are getting better. Comparison of disparities in pay, employment and unemployment among different ethnic groups shows that there has been little change over the past 25 years. Indeed for black, Pakistani and Bangladeshi men and women pay gaps with white men and women have widened. While ‘there are some groups for some labour market outcomes where there is clear evidence of reducing ethnic penalties, the overriding impression is of stasis’ [48, 49].
The report rightly says that the system is no longer rigged against ethnic minorities, but when commentators attribute disadvantage to racism or racial discrimination, they are not typically arguing that the racism or racial discrimination is intentional. Indeed, the contention in the report that racism requires ‘the intent of the perpetrator as well as the perception of the victim’ contravenes the tenor of equality legislation which does not require proof of intention when a judgment as to whether discrimination has occurred is made. The report frequently focuses on racism at the individual level and here it rightly acknowledges its toxic nature on social media. Much less attention is paid, however, to the historical roots of racism [see [24]] or the structural forces that sustain it, or (as we shall see below) racism at the institutional level.
The Commission is clearly correct in recognizing that race and ethnic disparities do not in themselves demonstrate racism or discrimination. Correlation is not the same as causation. The commission’s approach in seeking to explain disparities is, however, deeply flawed. It divides disparities into two kinds, explained and unexplained, as we saw earlier. This means that disparities ‘are either explained by factors other than racism – or there is no evidence so they are unexplained’…there is [thus] no way, within its framework, to demonstrate that racism or discrimination…is actually causing the observed disparities in outcomes’ [50]. Even worse is its use of regression analysis from which it commonly infers in the report that racism is a less significant factor than other factors. This is a statistical error. ‘The impact of someone’s race on their health cannot be dismissed by saying “well, actually, poverty is the “real” cause, if poverty and race are – as they are in the UK – inextricably linked…Structural inequality is a complex interplay of causes and outcomes – and one variable can be both at once. Sticking in as many variables as possible on one side of a regression and claiming you’ve “explained” away race and racism…is not a credible analysis’ [50]. This has been labeled ‘“the garbage can” approach to statistics: the calculations appear to be scientific, but in reality they are meaningless’. What is more, this approach ‘displays a basic misunderstanding of how racism works. Often various statistical factors, such as people’s socioeconomic status or geographic location, are themselves products of racism’ [51]. The higher mortality rate of ethnic minorities from COVID-19 ‘can be attributed to living in deprived areas, crowded housing, and being more exposed to the virus at work and at home – these conditions themselves the result of longstanding inequalities and structural racism’ [52].
At the launch of the report and in the press release, Tony Sewell stated that the report found no evidence of institutional racism. This was a significant and incendiary claim because the Macpherson report had argued in 1999 that institutional racism was rife in Britain. The Commission’s report itself, however, is more circumspect, in acknowledging the existence of institutional (as well as individual) discrimination and even recognizing merit in MacPherson’s definition of the term. And yet when we examine the report, there is an extreme reluctance to point to any examples of institutional racism. An obvious example is the Windrush scandal in 2018 which saw significant numbers of Black Caribbeans being wrongly detained and in some cases deported by the Home Office. The Commission mentions the scandal but emphasizes that it was not intentionally designed or deliberately targeted. What it does not mention is that an independent review led by Wendy Williams found that the Home Office had displayed ‘institutional ignorance and thoughtlessness’ on race issues, ‘consistent with some elements of the definition of institutional racism’. Interestingly, she adds a coda which is pertinent to the authors of the Sewell report: ‘There seems to be a misconception that racism is confined to decisions made with racist motivations…This is a misunderstanding of both the law and racism generally’ (Williams quoted in [53]).
The extreme reluctance to identify any examples of institutional racism is further evidenced by the one occasion when the question of an organization being institutionally race is addressed. The charge that the police remain institutionally racist is dismissed on the flimsy grounds that there is more reporting and recording of racist incidents. It seems remarkable that the report did not examine, as previous research has done (see [54]), whether prevailing cultural assumptions and routine practices in the police continue to have a discriminatory impact, before reaching its judgment. The crime and policing chapter, while providing some pertinent data, ultimately shies away from seeing institutional discrimination, preferring instead to believe that there are a few ‘bad apples’ or ‘rogue elements’.
Rather than flirting with the notion that powerful organizations may be institutionally racist, the report tends to be uncritical towards them. While I recognize that it may be politic to assert that the government which has commissioned the report takes race equality seriously and has sought to implement the recommendations of previous reports, both claims are highly questionable. Arguably, the recommendation to the government to strengthen the body responsible for enforcing anti-discrimination legislation is a brave one, but it is notable that it eschews any comment on the EHRC’s steady emasculation since 2010 and does not incorporate a recommendation to the government to activate the socio-economic duty, Section 1 of the Equality Act and in this way address the socio-economic disadvantage highlighted in the report. What is more evident is that the issue of race inequality, which was propelled into the limelight by the Macpherson report and for a period was taken seriously by the Labour government, dropped off the agenda until the Black Lives Movement resuscitated it. The consequence of the neglect to address race equality in the intervening period is that many of the recommendations the report makes have been made before. Examples are manifold: in education, improving data collection, monitoring and quality of analysis, and providing better careers guidance; in employment, advancing ‘nudge’-style procedures such as name blind CVs, transparent performance metrics, proactive mentoring and networking procedures; in policing, training in de-escalation techniques, increased monitoring by senior officers, more community involvement, measures to increase police diversity; and in health, more research. There is only one occasion when the Commission shows some exasperation when it fulminates that ‘the gap in achieving the right workforce mix has been driven by a lack of consistent political and police leadership focus on this issue over the last 40 years’ [38].
The report rightly acknowledges the agency of ethnic minorities who have indeed been resourceful despite facing unique hurdles. Although the Commissioners acknowledge the importance of structural factors such as socio-economic position in influencing outcomes, their emphasis on agency means that they are often concerned to emphasize what people can do for themselves. This is important, but to produce significant change in, say, employment or health outcomes, we need to address the structural factors responsible. And there is a danger in honing in on individuals, families and communities rather than structural factors. The danger is that the responsibility for disadvantage is seen to lie within those individuals, families and communities. This is evident when the report explains why some minority groups have been less successful in transcending class disadvantage than others. ‘Its answer is “family structures” and “cultural traditions”’ [55]. Family breakdown, which is in fact an attribute of poverty, entails negative outcomes for Black Caribbeans, while lack of fluency in English, among a small number of older women, purportedly holds back the economic advancement of Pakistani/Bangaladeshis. The report is at pains to point out that it is not blaming the communities in question, but in arguing that the causes of disadvantage lie primarily within those groups, ‘social issues…are reframed as moral choices and the behaviour of individuals’ [55]. Despite the protestations of the authors of the report, this is tantamount to a victim blaming discourse.
5. Conclusion
Black Lives Matters (BLM) have put structural racism back on the agenda, but the initial optimism felt by many anti-racists that at last action would be taken to promote racial justice has been somewhat dashed by the backlash to this agenda. This backlash needs to be seen in the context of an anti-political correctness discourse which is extremely pervasive. This discourse comprises a major interpretive framework in the media uncritically reproduced by many journalists. Populist politicians are all too happy to propagate this discourse and indeed have not been averse to fermenting culture wars and pursue an anti-woke agenda which they believe play well with their constituents. The Sewell report was commissioned by the government in the UK because it needed, given the popularity of the BLM movement, to be seen to be responding. The government was careful in its choice of Chair and choice of Commissioners, and we should not therefore be too surprised that the final report draws upon many right wing tropes and was consonant with the positions earlier taken by Boris Johnson, Munira Mirza and Tony Sewell: challenging the pertinence of key concepts such as institutional racism, white privilege and decolonizing; questioning the purportedly subjective definition of a racist incident; stressing what people can do for themselves; critiquing diversity specialists, unconscious bias training and quotas; downplaying racism and playing up geography and the White working class; presenting a caricature of antiracism as pulling down statues, excising White authors etc.; dismissing what it characterizes as identity based politics; and extolling Britain as a beacon to the world. Far from the report moving us beyond the culture wars, it has itself become employed as a weapon in these wars. ‘The report strikes a major blow against institutional wokeness’ shouts one academic [56]. In the process, the report has become the latest manifestation of a strategy to delegitimize antiracism; ‘anyone who talks about racism is simply doing Britain down, smearing white people, forcing a woke agenda “down our throats”’ [56].
\n',keywords:"racism, political correctness, culture wars, discourse, racial and ethnic disparities",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/78439.pdf",chapterXML:"https://mts.intechopen.com/source/xml/78439.xml",downloadPdfUrl:"/chapter/pdf-download/78439",previewPdfUrl:"/chapter/pdf-preview/78439",totalDownloads:190,totalViews:0,totalCrossrefCites:1,dateSubmitted:"July 23rd 2021",dateReviewed:"August 15th 2021",datePrePublished:"September 13th 2021",datePublished:"May 25th 2022",dateFinished:"September 5th 2021",readingETA:"0",abstract:"The murder of George Floyd by police officers in the US in 2020 reignited the Black live matter movement and reverberated across the world. In the UK many young people demonstrated their determination to resist structural racism and a number of organizations subsequently acknowledged the need to take action to promote race equality and reflect upon their historical role in colonialism and slavery. At the same time, resistance to these challenges has mounted, with right-wing news media and the UK government drawing upon an anti-woke or anti-PC discourse to disparage attempts to combat structural racism and decolonise the curriculum. This chapter argues that the campaign to discredit anti-racism culminated in 2021 in the production of the Sewell report commissioned by the government. This chapter critically examines this report and the discourse which underpins the report. The discourse is consonant with that of the anti-woke campaign propagated by the right-wing news media and the UK government, and entails the reproductoion of rather than opposition to structural racism.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/78439",risUrl:"/chapter/ris/78439",signatures:"Andrew Pilkington",book:{id:"10914",type:"book",title:"Effective Elimination of Structural Racism",subtitle:null,fullTitle:"Effective Elimination of Structural Racism",slug:"effective-elimination-of-structural-racism",publishedDate:"May 25th 2022",bookSignature:"Erick Guerrero",coverURL:"https://cdn.intechopen.com/books/images_new/10914.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83969-283-3",printIsbn:"978-1-83969-282-6",pdfIsbn:"978-1-83969-284-0",isAvailableForWebshopOrdering:!0,editors:[{id:"294761",title:"Dr.",name:"Erick",middleName:null,surname:"Guerrero",slug:"erick-guerrero",fullName:"Erick Guerrero"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"417603",title:"Prof.",name:"Andrew",middleName:null,surname:"Pilkington",fullName:"Andrew Pilkington",slug:"andrew-pilkington",email:"andy.pilkington@northampton.ac.uk",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"University of Northampton",institutionURL:null,country:{name:"United Kingdom"}}}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Political correctness and the anti-woke agenda",level:"1"},{id:"sec_3",title:"3. Changing the narrative: the Sewell report",level:"1"},{id:"sec_4",title:"4. Challenging the narrative",level:"1"},{id:"sec_5",title:"5. Conclusion",level:"1"}],chapterReferences:[{id:"B1",body:'[Alibhai-Brown, Y. In defence of political correctness, London: Biteback Publishing, 2018.]'},{id:"B2",body:'[Shipman, T. Voters seek return to common sense in revolt against political correctness. Sunday Times. 2020. Available from Voters seek return to common sense in revolt against political correctness | News | The Sunday Times (thetimes.co.uk) [Accessed 2021-02-09].]'},{id:"B3",body:'[Parris, M. Let’s stop kidding ourselves we’re tolerant. Sunday Times. 2019. Available from Let’s stop kidding ourselves we’re tolerant | Comment | The Times [Accessed 2021-02-10].]'},{id:"B4",body:'[Phillips. T. When you erase a nation’s past you threaten its future. Times. 2020. 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\r\n\tThe four topics of this book series - Pollution; Environmental Resilience and Management; Ecosystems and Biodiversity; and Water Science - will address important areas of advancement in the environmental sciences. They will represent an excellent initial grouping of published works on these critical topics.
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He also has an honorary appointment to serve as a Collaborative Professor at Kanazawa University, Japan, from Mar 2015 to the present. \nFormerly, Dr. Rahman was a faculty member of the University of Chittagong, Bangladesh, affiliated with the Department of Chemistry (Oct 2002 to Mar 2012) and the Department of Applied Chemistry and Chemical Engineering (Mar 2012 to Sep 2015). Dr. Rahman was also adjunctly attached with Kanazawa University, Japan (Visiting Research Professor, Dec 2014 to Mar 2015; JSPS Postdoctoral Research Fellow, Apr 2012 to Mar 2014), and Tokyo Institute of Technology, Japan (TokyoTech-UNESCO Research Fellow, Oct 2004–Sep 2005). \nHe received his Ph.D. degree in Environmental Analytical Chemistry from Kanazawa University, Japan (2011). He also achieved a Diploma in Environment from the Tokyo Institute of Technology, Japan (2005). Besides, he has an M.Sc. degree in Applied Chemistry and a B.Sc. degree in Chemistry, all from the University of Chittagong, Bangladesh. \nDr. Rahman’s research interest includes the study of the fate and behavior of environmental pollutants in the biosphere; design of low energy and low burden environmental improvement (remediation) technology; implementation of sustainable waste management practices for treatment, handling, reuse, and ultimate residual disposition of solid wastes; nature and type of interactions in organic liquid mixtures for process engineering design applications.",institutionString:null,institution:{name:"Fukushima University",institutionURL:null,country:{name:"Japan"}}},editorTwo:{id:"201020",title:"Dr.",name:"Zinnat Ara",middleName:null,surname:"Begum",slug:"zinnat-ara-begum",fullName:"Zinnat Ara Begum",profilePictureURL:"https://mts.intechopen.com/storage/users/201020/images/system/201020.jpeg",biography:"Zinnat A. 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He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. 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He is currently a full professor in\nthe Department of Automation and Applied Informatics at the\nsame university. Dr. Voloşencu is the author of ten books, seven\nbook chapters, and more than 160 papers published in journals\nand conference proceedings. He has also edited twelve books and\nhas twenty-seven patents to his name. He is a manager of research grants, editor in\nchief and member of international journal editorial boards, a former plenary speaker, a member of scientific committees, and chair at international conferences. His\nresearch is in the fields of control systems, control of electric drives, fuzzy control\nsystems, neural network applications, fault detection and diagnosis, sensor network\napplications, monitoring of distributed parameter systems, and power ultrasound\napplications. 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Particularly interesting are models of various types of more compound functions and abilities, various and more general fundamental principles (e.g., regarding architecture, organization, learning, development, etc.) found at various spatial and temporal levels.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/23.jpg",keywords:"Single-Neuron Modeling, Sensory Processing, Motor Control, Memory and Synaptic Pasticity, Attention, Identification, Categorization, Discrimination, Learning, Development, Axonal Patterning and Guidance, Neural Architecture, Behaviours and Dynamics of Networks, Cognition and the Neuroscientific Basis of Consciousness"},{id:"24",title:"Computer Vision",scope:"The scope of this topic is to disseminate the recent advances in the rapidly growing field of computer vision from both the theoretical and practical points of view. Novel computational algorithms for image analysis, scene understanding, biometrics, deep learning and their software or hardware implementations for natural and medical images, robotics, VR/AR, applications are some research directions relevant to this topic.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/24.jpg",keywords:"Image Analysis, Scene Understanding, Biometrics, Deep Learning, Software Implementation, Hardware Implementation, Natural Images, Medical Images, Robotics, VR/AR"},{id:"25",title:"Evolutionary Computation",scope:"Evolutionary computing is a paradigm that has grown dramatically in recent years. This group of bio-inspired metaheuristics solves multiple optimization problems by applying the metaphor of natural selection. It so far has solved problems such as resource allocation, routing, schedule planning, and engineering design. Moreover, in the field of machine learning, evolutionary computation has carved out a significant niche both in the generation of learning models and in the automatic design and optimization of hyperparameters in deep learning models. This collection aims to include quality volumes on various topics related to evolutionary algorithms and, alternatively, other metaheuristics of interest inspired by nature. For example, some of the issues of interest could be the following: Advances in evolutionary computation (Genetic algorithms, Genetic programming, Bio-inspired metaheuristics, Hybrid metaheuristics, Parallel ECs); Applications of evolutionary algorithms (Machine learning and Data Mining with EAs, Search-Based Software Engineering, Scheduling, and Planning Applications, Smart Transport Applications, Applications to Games, Image Analysis, Signal Processing and Pattern Recognition, Applications to Sustainability).",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",keywords:"Genetic Algorithms, Genetic Programming, Evolutionary Programming, Evolution Strategies, Hybrid Algorithms, Bioinspired Metaheuristics, Ant Colony Optimization, Evolutionary Learning, Hyperparameter Optimization"},{id:"26",title:"Machine Learning and Data Mining",scope:"The scope of machine learning and data mining is immense and is growing every day. It has become a massive part of our daily lives, making predictions based on experience, making this a fascinating area that solves problems that otherwise would not be possible or easy to solve. This topic aims to encompass algorithms that learn from experience (supervised and unsupervised), improve their performance over time and enable machines to make data-driven decisions. It is not limited to any particular applications, but contributions are encouraged from all disciplines.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/26.jpg",keywords:"Intelligent Systems, Machine Learning, Data Science, Data Mining, Artificial Intelligence"},{id:"27",title:"Multi-Agent Systems",scope:"Multi-agent systems are recognised as a state of the art field in Artificial Intelligence studies, which is popular due to the usefulness in facilitation capabilities to handle real-world problem-solving in a distributed fashion. The area covers many techniques that offer solutions to emerging problems in robotics and enterprise-level software systems. Collaborative intelligence is highly and effectively achieved with multi-agent systems. Areas of application include swarms of robots, flocks of UAVs, collaborative software management. Given the level of technological enhancements, the popularity of machine learning in use has opened a new chapter in multi-agent studies alongside the practical challenges and long-lasting collaboration issues in the field. It has increased the urgency and the need for further studies in this field. We welcome chapters presenting research on the many applications of multi-agent studies including, but not limited to, the following key areas: machine learning for multi-agent systems; modeling swarms robots and flocks of UAVs with multi-agent systems; decision science and multi-agent systems; software engineering for and with multi-agent systems; tools and technologies of multi-agent systems.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/27.jpg",keywords:"Collaborative Intelligence, Learning, Distributed Control System, Swarm Robotics, Decision Science, Software Engineering"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:{title:"Artificial Intelligence",id:"14"},selectedSubseries:null},seriesLanding:{item:{id:"25",title:"Environmental Sciences",doi:"10.5772/intechopen.100362",issn:"2754-6713",scope:"\r\n\tScientists have long researched to understand the environment and man’s place in it. The search for this knowledge grows in importance as rapid increases in population and economic development intensify humans’ stresses on ecosystems. Fortunately, rapid increases in multiple scientific areas are advancing our understanding of environmental sciences. Breakthroughs in computing, molecular biology, ecology, and sustainability science are enhancing our ability to utilize environmental sciences to address real-world problems.
\r\n\tThe four topics of this book series - Pollution; Environmental Resilience and Management; Ecosystems and Biodiversity; and Water Science - will address important areas of advancement in the environmental sciences. They will represent an excellent initial grouping of published works on these critical topics.
",coverUrl:"https://cdn.intechopen.com/series/covers/25.jpg",latestPublicationDate:"April 13th, 2022",hasOnlineFirst:!1,numberOfOpenTopics:4,numberOfPublishedChapters:9,numberOfPublishedBooks:1,editor:{id:"197485",title:"Dr.",name:"J. Kevin",middleName:null,surname:"Summers",fullName:"J. Kevin Summers",profilePictureURL:"https://mts.intechopen.com/storage/users/197485/images/system/197485.jpg",biography:"J. Kevin Summers is a Senior Research Ecologist at the Environmental Protection Agency’s (EPA) Gulf Ecosystem Measurement and Modeling Division. He is currently working with colleagues in the Sustainable and Healthy Communities Program to develop an index of community resilience to natural hazards, an index of human well-being that can be linked to changes in the ecosystem, social and economic services, and a community sustainability tool for communities with populations under 40,000. He leads research efforts for indicator and indices development. Dr. Summers is a systems ecologist and began his career at the EPA in 1989 and has worked in various programs and capacities. This includes leading the National Coastal Assessment in collaboration with the Office of Water which culminated in the award-winning National Coastal Condition Report series (four volumes between 2001 and 2012), and which integrates water quality, sediment quality, habitat, and biological data to assess the ecosystem condition of the United States estuaries. He was acting National Program Director for Ecology for the EPA between 2004 and 2006. He has authored approximately 150 peer-reviewed journal articles, book chapters, and reports and has received many awards for technical accomplishments from the EPA and from outside of the agency. Dr. Summers holds a BA in Zoology and Psychology, an MA in Ecology, and Ph.D. in Systems Ecology/Biology.",institutionString:null,institution:{name:"Environmental Protection Agency",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"38",title:"Pollution",keywords:"Human activity, Pollutants, Reduced risks, Population growth, Waste disposal, Remediation, Clean environment",scope:"\r\n\tPollution is caused by a wide variety of human activities and occurs in diverse forms, for example biological, chemical, et cetera. In recent years, significant efforts have been made to ensure that the environment is clean, that rigorous rules are implemented, and old laws are updated to reduce the risks towards humans and ecosystems. However, rapid industrialization and the need for more cultivable sources or habitable lands, for an increasing population, as well as fewer alternatives for waste disposal, make the pollution control tasks more challenging. Therefore, this topic will focus on assessing and managing environmental pollution. It will cover various subjects, including risk assessment due to the pollution of ecosystems, transport and fate of pollutants, restoration or remediation of polluted matrices, and efforts towards sustainable solutions to minimize environmental pollution.
",annualVolume:11966,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/38.jpg",editor:{id:"110740",title:"Dr.",name:"Ismail M.M.",middleName:null,surname:"Rahman",fullName:"Ismail M.M. Rahman",profilePictureURL:"https://mts.intechopen.com/storage/users/110740/images/2319_n.jpg",institutionString:null,institution:{name:"Fukushima University",institutionURL:null,country:{name:"Japan"}}},editorTwo:{id:"201020",title:"Dr.",name:"Zinnat Ara",middleName:null,surname:"Begum",fullName:"Zinnat Ara Begum",profilePictureURL:"https://mts.intechopen.com/storage/users/201020/images/system/201020.jpeg",institutionString:null,institution:{name:"Fukushima University",institutionURL:null,country:{name:"Japan"}}},editorThree:null,editorialBoard:[{id:"252368",title:"Dr.",name:"Meng-Chuan",middleName:null,surname:"Ong",fullName:"Meng-Chuan Ong",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRVotQAG/Profile_Picture_2022-05-20T12:04:28.jpg",institutionString:null,institution:{name:"Universiti Malaysia Terengganu",institutionURL:null,country:{name:"Malaysia"}}},{id:"63465",title:"Prof.",name:"Mohamed Nageeb",middleName:null,surname:"Rashed",fullName:"Mohamed Nageeb Rashed",profilePictureURL:"https://mts.intechopen.com/storage/users/63465/images/system/63465.gif",institutionString:null,institution:{name:"Aswan University",institutionURL:null,country:{name:"Egypt"}}},{id:"187907",title:"Dr.",name:"Olga",middleName:null,surname:"Anne",fullName:"Olga Anne",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBE5QAO/Profile_Picture_2022-04-07T09:42:13.png",institutionString:null,institution:{name:"Klaipeda State University of Applied Sciences",institutionURL:null,country:{name:"Lithuania"}}}]},{id:"39",title:"Environmental Resilience and Management",keywords:"Anthropic effects, Overexploitation, Biodiversity loss, Degradation, Inadequate Management, SDGs adequate practices",scope:"\r\n\tThe environment is subject to severe anthropic effects. Among them are those associated with pollution, resource extraction and overexploitation, loss of biodiversity, soil degradation, disorderly land occupation and planning, and many others. These anthropic effects could potentially be caused by any inadequate management of the environment. However, ecosystems have a resilience that makes them react to disturbances which mitigate the negative effects. It is critical to understand how ecosystems, natural and anthropized, including urban environments, respond to actions that have a negative influence and how they are managed. It is also important to establish when the limits marked by the resilience and the breaking point are achieved and when no return is possible. The main focus for the chapters is to cover the subjects such as understanding how the environment resilience works, the mechanisms involved, and how to manage them in order to improve our interactions with the environment and promote the use of adequate management practices such as those outlined in the United Nations’ Sustainable Development Goals.
",annualVolume:11967,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/39.jpg",editor:{id:"137040",title:"Prof.",name:"Jose",middleName:null,surname:"Navarro-Pedreño",fullName:"Jose Navarro-Pedreño",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRAXrQAO/Profile_Picture_2022-03-09T15:50:19.jpg",institutionString:"Miguel Hernández University of Elche, Spain",institution:null},editorTwo:null,editorThree:null,editorialBoard:[{id:"177015",title:"Prof.",name:"Elke Jurandy",middleName:null,surname:"Bran Nogueira Cardoso",fullName:"Elke Jurandy Bran Nogueira Cardoso",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRGxzQAG/Profile_Picture_2022-03-25T08:32:33.jpg",institutionString:"Universidade de São Paulo, Brazil",institution:null},{id:"211260",title:"Dr.",name:"Sandra",middleName:null,surname:"Ricart",fullName:"Sandra Ricart",profilePictureURL:"https://mts.intechopen.com/storage/users/211260/images/system/211260.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}}]},{id:"40",title:"Ecosystems and Biodiversity",keywords:"Ecosystems, Biodiversity, Fauna, Taxonomy, Invasive species, Destruction of habitats, Overexploitation of natural resources, Pollution, Global warming, Conservation of natural spaces, Bioremediation",scope:"\r\n\tIn general, the harsher the environmental conditions in an ecosystem, the lower the biodiversity. Changes in the environment caused by human activity accelerate the impoverishment of biodiversity.
\r\n\r\n\tBiodiversity refers to “the variability of living organisms from any source, including terrestrial, marine and other aquatic ecosystems and the ecological complexes of which they are part; it includes diversity within each species, between species, and that of ecosystems”.
\r\n\r\n\tBiodiversity provides food security and constitutes a gene pool for biotechnology, especially in the field of agriculture and medicine, and promotes the development of ecotourism.
\r\n\r\n\tCurrently, biologists admit that we are witnessing the first phases of the seventh mass extinction caused by human intervention. It is estimated that the current rate of extinction is between a hundred and a thousand times faster than it was when man first appeared. The disappearance of species is caused not only by an accelerated rate of extinction, but also by a decrease in the rate of emergence of new species as human activities degrade the natural environment. The conservation of biological diversity is "a common concern of humanity" and an integral part of the development process. Its objectives are “the conservation of biological diversity, the sustainable use of its components, and the fair and equitable sharing of the benefits resulting from the use of genetic resources”.
\r\n\r\n\tThe following are the main causes of biodiversity loss:
\r\n\r\n\t• The destruction of natural habitats to expand urban and agricultural areas and to obtain timber, minerals and other natural resources.
\r\n\r\n\t• The introduction of alien species into a habitat, whether intentionally or unintentionally which has an impact on the fauna and flora of the area, and as a result, they are reduced or become extinct.
\r\n\r\n\t• Pollution from industrial and agricultural products, which devastate the fauna and flora, especially those in fresh water.
\r\n\r\n\t• Global warming, which is seen as a threat to biological diversity, and will become increasingly important in the future.
",annualVolume:11968,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/40.jpg",editor:{id:"209149",title:"Prof.",name:"Salustiano",middleName:null,surname:"Mato",fullName:"Salustiano Mato",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRLREQA4/Profile_Picture_2022-03-31T10:23:50.png",institutionString:null,institution:{name:"University of Vigo",institutionURL:null,country:{name:"Spain"}}},editorTwo:{id:"60498",title:"Prof.",name:"Josefina",middleName:null,surname:"Garrido",fullName:"Josefina Garrido",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRj1VQAS/Profile_Picture_2022-03-31T10:06:51.jpg",institutionString:null,institution:{name:"University of Vigo",institutionURL:null,country:{name:"Spain"}}},editorThree:{id:"464288",title:"Dr.",name:"Francisco",middleName:null,surname:"Ramil",fullName:"Francisco Ramil",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003RI7lHQAT/Profile_Picture_2022-03-31T10:15:35.png",institutionString:null,institution:{name:"University of Vigo",institutionURL:null,country:{name:"Spain"}}},editorialBoard:[{id:"220987",title:"Dr.",name:"António",middleName:"Onofre",surname:"Soares",fullName:"António Soares",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRNtzQAG/Profile_Picture_1644499672340",institutionString:null,institution:{name:"University of the Azores",institutionURL:null,country:{name:"Portugal"}}}]},{id:"41",title:"Water Science",keywords:"Water, Water resources, Freshwater, Hydrological processes, Utilization, Protection",scope:"\r\n\tWater is not only a crucial substance needed for biological life on Earth, but it is also a basic requirement for the existence and development of the human society. Owing to the importance of water to life on Earth, early researchers conducted numerous studies and analyses on the liquid form of water from the perspectives of chemistry, physics, earth science, and biology, and concluded that Earth is a "water polo". Water covers approximately 71% of Earth's surface. However, 97.2% of this water is seawater, 21.5% is icebergs and glaciers, and only 0.65% is freshwater that can be used directly by humans. As a result, the amount of water reserves available for human consumption is limited. The development, utilization, and protection of freshwater resources has become the focus of water science research for the continued improvement of human livelihoods and society.
\r\n\r\n\tWater exists as solid, liquid, and gas within Earth’s atmosphere, lithosphere, and biosphere. Liquid water is used for a variety of purposes besides drinking, including power generation, ecology, landscaping, and shipping. Because water is involved in various environmental hydrological processes as well as numerous aspects of the economy and human society, the study of various phenomena in the hydrosphere, the laws governing their occurrence and development, the relationship between the hydrosphere and other spheres of Earth, and the relationship between water and social development, are all part of water science. Knowledge systems for water science are improving continuously. Water science has become a specialized field concerned with the identification of its physical, chemical, and biological properties. In addition, it reveals the laws of water distribution, movement, and circulation, and proposes methods and tools for water development, utilization, planning, management, and protection. Currently, the field of water science covers research related to topics such as hydrology, water resources and water environment. It also includes research on water related issues such as safety, engineering, economy, law, culture, information, and education.
",annualVolume:11969,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/41.jpg",editor:{id:"349630",title:"Dr.",name:"Yizi",middleName:null,surname:"Shang",fullName:"Yizi Shang",profilePictureURL:"https://mts.intechopen.com/storage/users/349630/images/system/349630.jpg",institutionString:"China Institute of Water Resources and Hydropower Research",institution:{name:"China Institute of Water Resources and Hydropower Research",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"216491",title:"Dr.",name:"Charalampos",middleName:null,surname:"Skoulikaris",fullName:"Charalampos Skoulikaris",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRMsbQAG/Profile_Picture_2022-04-21T09:31:55.jpg",institutionString:null,institution:{name:"Aristotle University of Thessaloniki",institutionURL:null,country:{name:"Greece"}}},{id:"300124",title:"Prof.",name:"Thomas",middleName:null,surname:"Shahady",fullName:"Thomas Shahady",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002kuIgmQAE/Profile_Picture_2022-03-18T07:32:10.jpg",institutionString:null,institution:{name:"Lynchburg College",institutionURL:null,country:{name:"United States of America"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/23445",hash:"",query:{},params:{id:"23445"},fullPath:"/chapters/23445",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()