\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"12",leadTitle:null,fullTitle:"Numerical Simulations - Examples and Applications in Computational Fluid Dynamics",title:"Numerical Simulations",subtitle:"Examples and Applications in Computational Fluid Dynamics",reviewType:"peer-reviewed",abstract:"This book will interest researchers, scientists, engineers and graduate students in many disciplines, who make use of mathematical modeling and computer simulation. Although it represents only a small sample of the research activity on numerical simulations, the book will certainly serve as a valuable tool for researchers interested in getting involved in this multidisciplinary field. 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His research is concerned with the mathematical analysis of numerical algorithms for partial differential equations with special interests in finite volume and finite element methods. \nAfter the study of Mathematics at the University of Kharkiv (Ukraine) he earned a Ph.D. from the University of Technology at Dresden in 1987. The University of Erlangen-Nürnberg awarded him a higher doctoral degree (habilitation) in 1995. From 1998 to 2001, he held the post of an Associate Professor of Numerical Mathematics at the University of Magdeburg. \nHe is the author of about 100 scientific papers, among them two co-authored books on numerical methods for partial differential equations.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"3",totalChapterViews:"0",totalEditedBooks:"2",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"607",title:"Mathematical Modeling",slug:"numerical-analysis-and-scientific-computing-mathematical-modeling"}],chapters:[{id:"12611",title:"Numerical Simulation in Steady Flow of Non-Newtonian Fluids in Pipes with Circular Cross-Section",doi:"10.5772/12900",slug:"numerical-simulation-in-steady-flow-of-non-newtonian-fluids-in-pipes-with-circular-cross-section",totalDownloads:6007,totalCrossrefCites:0,totalDimensionsCites:3,hasAltmetrics:0,abstract:null,signatures:"F.j. 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It is more urgent than ever to find alternative ways to develop the Amazon. This realization comes with the science-based analysis that the Amazon may have come much closer to a tipping point than previously thought. Recent analysis [1] lends support to the idea that the whole Amazon system might flip to second stable climate-vegetation equilibrium, with degraded savannas covering most of the central, southern and eastern portions of the basin.
\nThe drivers of such change are deforestation, climate change and increased forest fires. Given the simultaneous and synergistic impact of these drivers of change, total deforestation must not exceed 20–25% to avoid transgressing a potentially irreversible tipping point.
\nGlobal climate considerations also matter: CO2 emissions from forest burning may well be the biggest unresolved global climate challenge. Without reductions in rainforest burning, including in the Amazon, international goals called for in ratified international Conventions for climate, biodiversity and water protection cannot be reached.
\nThe heightened critical risk to the Amazon forests calls for intensifying the search for disruptive socioeconomic alternatives and transformations. For many decades, contradicting strategies to develop the Amazon have been at work: conservation (we call it the
We argue that a radically different
The methodological approach of this study starts with a perfunctory examination of land use patterns in the Amazon. We examine two distinct models of land use pathways that in general terms may direct and define the maintenance or not of the Amazon forest. The first model is characterized by expansion of protected areas in the Amazon. It has been labeled ‘The First Way’. In the other model, it is prevalent intensive natural resources exploitation. It has been labeled ‘The Second Way’. In Section 3 of this chapter we briefly assess the overall results of these models in land use (for a comprehensive review, see [2]). We present updated literature data in support for current trends in land use changes, such as planned infrastructure, policies and evidence of ongoing land use processes and change.
\nWe pose two research questions to guide the next phase of the study: Overall, current and planned patterns of land use are environmentally sustainable in the long run? If not, what would be an alternative way? The answers are developed from the basic concepts proposed by [2] for the so-called Amazonia Third Way (A3W), which is based upon a novel economic model. This rests on an innovative, knowledge-based standing forest-flowing rivers bio-economy, valuing the Amazon’s renewable natural resources, biological and biomimetic assets, environmental services and biodiverse molecules and materials. A conceptual model of the A3W is proposed with the main drivers for its planning and implementation. Two of these drivers, namely Technological Drivers and Capacity Development, were considered key to the construction of A3W and are further developed in this work. The technologies of the 4th Industrial Revolution were coupled with core A3W guidelines, leading to the conceptual definition of the Amazonia 4.0. Figure 1 shows a diagram of the methodological approach used in this work.
\nMethodological diagram for the conceptual development of the Amazonia Third Way.
The Amazon forest biome has a total of 45.4% of its territory formed by protected areas and indigenous territories [3] as depicted in Figure 2. This large area where the forest is predominantly protected or managed in a sustainable way [4, 5] is the ballast that makes the First Way a possible model of land use for the Amazon. An effective example of the implementation of conservation policies by Amazonian governments is given by Brazil. In the 1990–2013 period, protected areas of the Amazon have grown from 11 to 125 million hectares and indigenous land have grown from 33 to 125 million hectares [6]. Indigenous territories and protected areas occupy 47.85% of the Brazilian Amazon [7].
\nProtect areas in the Amazon basin. Source: Conservation International [
On the other hand, the model of resource-intensive development (Second Way) rests mostly on economic activities that lead to the elimination of the forest and had cycles of intense growth for many decades. RAISG’s ‘Deforestation in the Amazon (1970–2013)’ (see Figure 3) study indicates that up to 9.7% of the region have been deforested until the year 2000, and that between that year and 2013 that rose to 13.3%, which represents 37% increase in 13 years [9]. Given that, by and large, Amazon deforestation rates increased in the last 5 years, it is likely that total deforestation is close to reaching 16% of the whole basin by 2018.
\nMapping of deforestation of the Amazon forest biome for two distinct periods: the total accumulated up to 2000 (red color) and the increment from 2000 to 2013 (black color). Source: RAISG [
Other studies show that protected areas and indigenous territories are not necessarily blocking deforestation completely. Although deforestation in indigenous territories in the Amazon remains relatively small, rates have grown 32% between 2016 and 2017 [7]. That points out that the barrier formed by indigenous land and other protected areas may vanish under the pressure of environmental crime and expansion of the commodities frontier, if adequate protection policies are not enforced. The increase of deforestation in some indigenous territories occurs at a time when the total rate of destruction of the Amazon rainforest fell by 16%, from 7892 km2 in August 2015–July 2016 to 6624 km2 in August 2016–July 2017. Notwithstanding the observed decrease, the level is still extremely high in absolute terms [7]. For the same period, the
Besides the current evidences indicating that protected areas may not be a good proxy for permanent forest conservation because the prevalent model of intensive use of natural resources is a permanent dynamic force toward disrupting it, there are evidences that the future can be even more challenging for the First Way to ensure forest conservation. Official Amazonian countries’ planned infrastructure developments indicate a huge increase in the construction of dams, roads, railroads and ports [11] throughout the Amazon basin. These types of infrastructure pose severe threats to the forestland through their construction and will almost certainly induce new developments of high deforestation profile.
\nIn the Brazilian Amazon, which comprises 65% of the whole biome, deforestation figures from 2005 to 2017 show that a period of consistent decrease from 2004 to 2012 may be now reversed (Figure 4).
\nAnnual deforestation rates in Brazilian Amazon (km2) from 2004 to 2017 and map of fraction of land cover change for 2010 (left panel) based on PRODES data [
Future land use change in the Amazon has been modeled [12, 13] for two rather opposed scenarios which lead to very different land cover changes (Figure 4). In one of them (the so-called ‘Fragmentation’ scenario), there is a continuous weakening of strict deforestation control policies successfully implemented from 2005 to 2012 in Brazilian Amazon and expansion of resource-intensive activities leading to agricultural and livestock expansion, resulting in over 50% of the Brazilian Amazon deforested by 2050. That is a scenario quite consistent with a progression in time of the Second Way. The other scenario in Figure 4 (the so-called ‘Sustainability’ scenario) calls for continuation and strengthening of the environmental policies to bring deforestation rates close to zero in the near future. It is the land cover change scenario compatible with the Third Way.
\nThe economic rationale to protect the tropical forests (The First Way or the ‘Sustainability’ scenario of Figure 4) rests to some degree upon the assumed low costs of maintaining intact forests as carbon storage and carbon sinks as a non-costly way to mitigate climate change in comparison to more expensive alternatives such as switching energy systems to renewable energy. Calculations for Brazil [15] estimate savings up to USD 100 billion/year to 2030 for Brazil to fulfill its NDC commitments to the Paris Accord if deforestation of the Amazon and Cerrado biomes can become smaller than 4000 km2/year and the bulk of its commitment to reduce national emissions 43% relative to 2005 emissions by 2030 come from land use policy and not from rapidly switching the energy matrix to renewable energy. However, it is clearly short-sighted to view only the carbon pathways as justification to preserve tropical forests. In fact, the Third Way Initiative raises various limitations of such approach (see [2]) and proposes that, in addition to ecosystems services, the economic potential of tropical forests rests on their biological and biomimetic assets to a larger extent.
\nIn this chapter, we analyze the issues and circumstances that have impeded to date socioeconomic development based on Amazon biodiversity assets to occur in large scale. We point out the major failures in dimensions such as concepts (imagination challenges), knowledge (research and information challenges) and implementation (governance and policy challenges & entrepreneurial capacity failures), and the lack of imagination of the potential of an innovative green economy based on nature that goes beyond the Amazon regional institutions. In the opportunity side, we present a summary of a major review in the scientific and technical literature, which identified more than 200 species of Amazonian plants with known potential to provide raw for an initial low-end bio-economy in the Amazon. Many biodiversity products of the Amazonian flora follow have established value chains. We did qualitative analysis on a sample of it to identify its main characteristics, problems, virtues and bottlenecks. This analysis included selected cases of innovative entrepreneurship leveraging relatively low-end technologies and evaluation of 25 enterprises that markets non-timber products of Amazonian biodiversity. The sample encompasses a range of segments, types, sizes and bio-assets processed.
\nThe challenges to achieving sustainable development in the Amazon can be broadly categorized in three categories, similarly to a conceptual framework laid out for planetary health [16]:
conceptual failures (imagination challenges), such as the vision of the Amazon as only a source of commodities for the world and the lack of imagination to create alternative, less socially and environmentally damaging development pathways based on the Amazon’s renewable natural resources (e.g., its rich biodiversity), with value added via technological innovations for an inclusive ‘bio-industrial’ model of development, generating higher income jobs and sustainable development.
knowledge failures (research and information challenges), such as reduced amount of funding to research institutions in the Amazon, focus of research and monitoring systems on land use transformations, insufficient R&D investments by the private sector, and lack of innovative research, for instance, to unveil the hidden economic and societal value of biological assets, that is, a ‘tropical model of development’.
implementation failures (governance and policy challenges & entrepreneurial capacity failures), such as the failure of Amazonian countries’ government to recognize the risks of current and past development policies and the inefficient implementation of a diversified economy by public and private actors and even the failure to share more equitably the benefits of the current resource-intensive economy, reducing social and income inequities.
The lack of imagination of the potential of an innovative green economy based on nature is not restricted to the Amazon regional institutions. Economic viability studies for the Amazon of serious institutions such as the World Bank almost completely ignore such potential. For example, recent studies [17] continue to see the value of forest products in an exclusively extractive way and assume very low returns. For example, less than $10 per year per hectare for non-timber products and just over $20 for sustainable selective logging. They ignore the concrete case of market success of agroforestry systems such as çaí, with proven annual returns of between $200 and $1000 per hectare [18], adding more than $1 billion annually to the regional economy [19].
\nThe intense resource-based agribusiness, mining and hydropower in the Amazon generate wealth and little of that is reinvested to propel health and education improvements within the Amazon beyond what is called for in the licensing process. That is in part due to the regressive taxation system and in part due to historical inefficiencies in investments in public services. For instance, the highest average per capita income region in Pará—annual per capita income of close to R$50,000—is the iron ore-rich Carajás area, with overall income higher than national average. However, social indicators such as health and education services are no different than other regions of the State of Pará and much lower than national averages. In summary, very little of the wealth remains in the region and improves the wellbeing of the population.
\nThe discourse on sustainability has been allowed to proceed as a sign of the times and to be aligned with global trends starting with the 1992 Earth Summit in Rio and to transmit an international aura of adherence, but in fact the concrete development policies for the Amazon never in fact deviated from the one devised by the military government out of geopolitical concerns: livestock and agricultural occupation to ensure sovereignty and exploitation of minerals, hydropower and fossil fuels as drivers for economic development.
\nThe intense and swift expansion of the Brazilian agriculture frontier in the Amazon resulted not only in the growth of the country’s GDP since the 1960s, but also in the rates of tree felling and greenhouse gas emissions—a consequence of conversion of forest landscapes into pasture for cattle raising and agricultural fields for grain production. Some numbers illustrate this human-orchestrated metamorphosis. Since 1997, more than 20 billion trees have been cut in the world’s largest rainforest. In 2016, more than half of the 8000 km2 of Amazon deforestation was transformed into new pastures. Currently, beef and dairy farming and production account for 45% of gross Brazilian GHG emissions.
\nThe main public policies responsible for the sharp reduction in deforestation from 2005 to 2014 seem to have already reached their limit, so much so that deforestation has been growing in 2015 and 2016, even in a period of historic economic recession, demonstrating once again the decoupling of deforestation with economic growth, neither when GDP grows nor when GDP shrinks. The underlying reasons for continued land cover change are more complex than simply responding to global markets.
\nUnfortunately, we may not have a long window of time to change course with respect sustainable pathways for the Amazon. Tipping points not to be transgressed for forest-climate stability are in the horizon. The synergistic effects of land cover and climate changes, and with increased forest fires due to a combination of forest degradation, use of fire in agriculture and droughts, make the risks even greater. Earth system modeling [2] shows that the synergistic combinations of those drivers could lead to a relatively rapid transition to new forest-climate equilibrium with loss 50–60% of the forest over eastern, southern and central Amazon, replaced by degraded savannas and dry forests. The sense of urgency to avert a systemic risk to the Amazon forests must be kept in mind in the search for solutions.
\nThe knowledge of nature, accumulated over 3.5 billion years of evolutionary processes, that finds in the Amazonian biodiversity one of its greatest showrooms, is a potentially very large bio-economic asset. The number of molecular substances with specific and usable functions is practically incalculable, since each existing species is itself a biochemical design laboratory. And most species are yet unknown and every 3 days, on average, one new species is discovered [20].
\nEven though a single substance with a desired function discovered by the study of living things in the Amazon could be biologically synthesized and produced industrially by laboratories to reduce costs or to provide quantities demanded for world consumption, the intrinsic knowledge that generated its form and function was stored in the forest and ready to be copied.
\nA review carried out in the scientific and technical literature as part of this work identified more than 200 species of Amazonian plants with known potential to provide raw for an initial low-end bio-economy in the Amazon. A reduced listing of the 20 very promising species that have been widely used, integrate local productive chains or show strong potential use in food, cosmetics, perfumery, medicinal, advanced materials and biotechnology have their distribution modeled. The listing includes rosewood (
Geographic distribution for rosewood (
Few of the biological assets of Amazonian biodiversity are known, others are being researched for their nutritional, structural, biochemical and market properties, to become products of future use.
\nA good example of this transition in the area of food is the açaí fruit of the
Like açaí, many of the Amazonian biodiversity foods are traditionally consumed by the local population, with marked flavors and excellent nutritional properties, as well as functional foods and nutraceuticals in many cases. Camu-camu (
The raw materials of Amazonian biodiversity are used in the industry of essences and oils to make cosmetic and perfumery products. As an example, the cumaru-ferro (
Açaí has also been studied and is used far beyond food: in the cosmetics sector its oil has properties for skin nutrition, revitalization and hydration, it contains omega 6, it is an antioxidant agent rich in polyphenols indicated for the formulation of anti-aging products [29, 30]. The anthocyanin present in large quantities in the açaí pulp was used in an application as a natural marker for teeth bacterial plaque [31] with large potential markets. In another development, nanoparticles of açaí oil are used to treat cancerous lesions [32]. Proving that applications of biodiversity raw materials tend to be innumerable, especially when combined with modern technological tools and cutting-edge research, a natural plastic was developed from açaí, with polyurethane produced from the seeds [33]. Discarding the abundant açaí berry seeds is a potential environmental problem in the pulp for food production cycle. The development of a plastic from the seeds also shows the possibilities of using by-products of a production chain in other associated chains for an even more efficient bio-economy with minimized externalities.
\nOther examples of uses of bio-composites are ucuuba (
Research in the medical field confirms the value of many indigenous traditional medicines and goes beyond, with its own and advanced research methods [36]. As an example, we can mention the chichuá (
Quercetin is a flavonoid that has the ability to suppress free radicals and thereby help preserve the brain and heart, keep the immune system active, protect the body against cancer, and act to prevent diseases, especially neurodegenerative diseases such as Alzheimer’s disease [48]. Quercetin, present in many foods but in low concentrations, is obtained from the natural purification process of the fava d’anta (
But the biological assets also have application in industry, with emphasis on endophytic fungi (
Another study with phytosterols isolated from endophytic fungus (
State-of-the-art research can unveil new and surprising uses even for forest assets that have been exploited for a long time. For instance, that is the case for natural rubber (
The biodiversity products of the Amazonian flora follow well-defined paths between the origins of the raw material, to its processed form for final consumption or to be reprocessed into components for very high specialty products. The value-added paths of biodiversity products involve multiple steps and social and business actors, varying according to the nature of the raw material, the products to be processed and the location of the harvesting and processing regions. As a general rule, the production of the raw material, which may be fruit, seed, sap, or other part or component of the plants occurs in the rural environment. They may come from primitive areas of natural forest or managed agroforestry systems (SAF), such as natural forests with extensive extractive species and intercropped planted forests.
\nThe rural area is home to communities where the first basic stages of preparation of the material collected or harvested for subsequent supply occur, such as cleaning, threshing, drying and other low-tech processes. Logistic processes such as the transport of the material from the collection and production sites to the pre-processing sites, storage and shipment to the processing centers also occur in the rural domain. In every aspect of this beginning of the value chain, there are opportunities for individual, family, cooperative or business based on local entrepreneurship.
\nAfter pre-processing, the materials are taken by boat or truck to companies or cooperative facilities in the Amazon or in another region in Brazil or in other Amazonian countries (e.g., Bolivia) where most or the entire product’s actual processing takes place, in facilities with varying degrees of automation. From there it is ready for consumption, locally or in markets elsewhere in Brazil or abroad. Based on a comprehensive study we conducted with value chains of five plant species, we developed a conceptual diagram that represents the main places, environments and activities carried out throughout the whole transformation cycles, from inputs origin to final consumption, as shown in Figure 6.
\nConceptual diagram of the location of the basic stages of value chains of Amazonian biodiversity products. Solid lines mean the last stage of a product in the value chain [
Not all paths shown in Figure 6 have fair remuneration in the value adding they represent. A 2005 study for cumaru (
Another evidence of such imbalance in the value sharing was revealed by our study of five value chains. While Brazil nut (
Differences between the many places where Brazil nut (
Recent corporate social responsibility efforts focused on purchasing biodiversity products from communities or cooperatives have generated more balanced and fair-trade relations, as with the operations of a range of forest products purchased by the Natura company and açaí purchased by the Sambazon company. However, the typical market distortions in the values paid to the extractivist-producer by intermediaries still has to be resolved.
\nAgroforestry systems (SAF—Sistema Agroflorestal) are agricultural crops intercropped with tree species, used to restore forests and recover degraded areas. The SAF technology overcomes terrain limitations, minimizes degradation risks inherent in agricultural activity and optimizes the achieved productivity. There is a reduction both in soil fertility losses and pest attacks. The use of trees is fundamental for the recovery of ecological functions, since it allows the reestablishment of much of the relationships between plants and animals. The tree components are inserted as a strategy to combat erosion and the contribution of organic matter, restoring soil fertility. Two successful tropical agroforestry projects illustrative of this system in the Amazon are the CAMTA cooperative [57] in Tomé Açu, in the state of Pará and the RECA cooperative [58] in Abunã, in the state of Rondônia.
\nWith the advancement of consumer markets, technologies and business models, new business development opportunities have emerged from the products of Amazon biodiversity. Four examples of this innovative entrepreneurship model were selected to demonstrate the combination of technology and corporate social responsibility for the generation and fair distribution of benefits to all links and actors of value chains. Two of the examples illustrate production companies and the other two examples show companies that developed digital platforms to increase efficiency in transactions and traceability of biodiversity products.
\nThe first example is the Tahuamanu company, a Bolivian producer of Brazil nut products, which illustrates the case of an Amazonian company that innovated by applying relatively low-end technologies, to all links of the Brazil nut productive chain, reflected in tremendous increases in productivity and benefits also to collectors at the base of the value chain. The 2016 severe El Niño-related drought in many parts of the Amazon may have wreaked havoc to the Brazil nut production that supplies the company. It is reported a 70% drop in harvest in 2017, responsible for laying off over 300 employees from his Cobija processing plants [59]. This unprecedented fall in production raise the question of the potential impact of climate change on the new development paradigm for the Amazon.
\nThe second example is the NATURA cosmetics company and its bio-industrial operations. It is probably the most successful case of exploration Amazon biodiversity assets within the most desirable parameters of socio-environmental excellence. Natura has developed a network of suppliers of raw materials from Amazon biodiversity that organizes production of almost 3000 families across the region. It supports training programs and community empowerment toward sustainability. The example of the ucuuba butter shows how the combination of innovative R&D and training communities in sustainable exploitation can deliver good results. Ucuuba trees were used as timber for broom sticks and that was accelerating risks of tree extinction. Butter was developed out of the ucuuba seeds and that new product found its way in cosmetics of high added-value. Floodplain communities of the Marajó Island were trained to collect and pre-process the seeds for sale to Natura and to other companies which also process ucuuba butter. The net profit of those operations for those families is three times larger per year as compared to the only once income for felling the tree. Natura is also promoting the bio-industrialization in the Amazon itself. It opened the Ecopark, an industrial complex in Benevides, near Belém, state of Pará.
\nThe third example is the FLORAUP digital platform that shows how information technology can be used to foster direct connection between local producers, from their remote locations in the forest, with potential buyers of their Amazon biodiversity products. After 1 year on air, the platform has only 57 registries, perhaps due to the relatively low digital connectivity of remote communities across the Amazon.
\nFinally, the fourth example is ORIGENS BRASIL, a production chain tracking digital platform. The platform allows anybody to know instantly the origin of the product that contains assets of Amazonian biodiversity since its raw material harvesting, its history and actors involved in the production. This is done simply by pointing a smartphone to the product packaging, which is equipped with a QR Code that accesses a remote live database. If one assumes that responsible consumers are an accelerating trend, such traceability platforms are in dire need for the Amazon.
\nNatural products developed on a sustainable basis have a long history in the Amazon since the rubber boom years. An increasing demand for these products for traditional and innovative uses in the food, cosmetics, perfumery and pharmaceutical industries has promoted new business opportunities in the Brazilian Amazon. As part of this trend, advances in biotechnology research have demonstrated a key role in expanding this potential, thus boosting the value chains that have as one of the main attributes the bio-industries focused on the processing of forest raw materials into biodiversity products.
\nThis research evaluated 25 enterprises that markets non-timber products of Amazonian biodiversity. The sample encompasses a range of segments, types, sizes and bio-assets processed. From international corporations with more than 100 years in the market of extracting the finest Amazonian essences, to innovative indigenous entrepreneurship of collecting and selling forest’s native species seeds in large amounts to support much needed reforestation efforts elsewhere.
\nThese industries deliver a vast array of products: It ranges from an exfoliating agent of açaí seed (Beraca company) to a powder form of the same fruit for energy drinks (Yerbalatina Phytoactives and 100% Amazônia companies). The Amazon-based bio-industry is also well-defined and consolidated in the supplying chains of oils and essences. As early as 1921, the essential oil extracted from the pau-rosa (
Another sector that has shown significant growth is the food, functional food and nutraceutical industries (e.g., Sambazon, Tahuamanu companies). Companies in this sector tap in the healthy food market and, by applying relatively low-end technologies, have put Amazon bio-actives available worldwide at anyone’s table. As a rule of thumb, most sectors have benefited from the adoption of newer and accessible technologies in their processing facilities. From Brazil nuts micro-factories for peeling seeds (COOPERACRE cooperative) to agrosilviculture producer’s cooperatives focused on traditional bio-industries (CAMTA, RECA cooperatives).
\nIn our study, we analyzed many products offered by the Amazon traditional bio-industries based on two defining axis: the amount of technology involved in the making of their products and the degree to which they are closer or further to their original state as furnished by Nature. It was a qualitative analysis and it shows status classes for these products. The diagram in Figure 8 shows the result of this qualitative analysis.
\nDiagram depicting status classes for Amazon bio-industry products based on the amount of technology involved in their making and the degree to which they are closer or further to their original raw material state as furnished by nature [
As it might be expected, values such as environmental sustainability, social development and fair-trade are a matter of concern for virtually all operations, to a greater or lesser extent, from small chestnut cooperatives to the giants of the essences and cosmetics sector. Nevertheless, there are reports of large traditional bio-industry operations that required botanical resources at large scales that have driven transformation in the supplying of natural asset, once coming from extractivism or agroforestry systems, into an asset generated from monocultures in the agroindustry’s usual patterns. It also disrupted traditional handmade extractive processes [60]. Accommodating increasing demands for bio-products with limitations inherent to Nature’s carrying capacity and traditional and local people culture, needs and potentials for insertion into new economic development paradigm is an imperative challenge for a real sustainable Amazon development strategy.
\nThe industrial sector transforming biodiversity assets into available consumables act in the interface between biodiversity, biotechnology and bio-industry, which involves a complex system of partnerships between companies, universities, research institutes, official financial agencies, organized communities and cooperatives inside and outside the Amazon region.
\nThe
In support of socioeconomic development, systemic innovations will also apply to enhancing biodiversity-based value chains. Ideally, these would shape a unique ‘Amazon-brand’ able to conquer global markets [61, 62, 63].
\nThe Amazonia Third Way Initiative promotes in-depth research on alternative pathways for sustainably developing the Amazon territory, in harmony with the twenty-first century’s Zeitgeist. Forests in the Amazon are the result of evolution over millions of years. Nature has developed a wide variety of biological assets, which include metabolic pathways, and genes of life on land, in aquatic ecosystems, and in their natural products—both, chemical and material—in conjunction with biomimetic assets, that is, the functions and processes used by nature.
\n4IR technologies increasingly harness these assets across many industries from pharmaceutics to energy, food, cosmetics, materials and mobility. Indeed, they are making profits, but to date these profits have not been channeled back to conserve the Amazon and to support the custodians of nature—indigenous and traditional communities—and also urban population in the region.
\nWithin a proper legal and ethical framework, the Amazonia Third Way Initiative offers unprecedented opportunities to local populations to develop a vibrant, socially inclusive ‘standing-forest, flowing-river’ green economy. By harnessing nature’s value through physical, digital and biological technologies of the 4th Industrial Revolution, we can simultaneously protect the Amazon ecosystems and their traditional custodians.
\nThe region is still largely disconnected from the main centers of technological innovation dealing with 4IR technologies and the advanced bio-economy. The Amazonia Third Way Initiative is conceived as a multi-level path toward a new inclusive bio-economy, combining a highly innovative, entrepreneurial and technological economy with the re-valuation of non-timber forest products and industries with low-end technologies.
\nThe conceptual framework for the
Determinants of sustainable pathways for the Amazon. The Amazonia third way initiative seeks ‘
At the broader level,
As mentioned before, the Third Way Initiative is not one more attempt to reconcile resource-intensive development with conservation. Instead, it will seek to implement the twenty-first century paradigm of knowledge societies to Amazon realities through research and development, entrepreneurship, twenty-first century skills and education, and fit for purpose sustainable development policies toward a standing forests-flowing rivers inclusive bio-economy.
\nWithin the Amazonia Third Way initiative, an approach has been developed to operationalize the principles and practices that will allow a proposed paradigm shift for Amazon sustainable development. It defines seven interconnected realms: (1) the existing natural knowledge; (2) the ability for learning from nature; (3) the capacity to applying biodiversity-based knowledge to human needs; (4) the capacity to producing biodiversity-based goods and solutions; (5) the insertion of biodiversity-originated products on a local-to-global bio-economy; (6) the fair sharing of socioeconomic benefits and life quality improvement for all; and (7) the rising of an Amazon Biome intrinsic valuing. With the advancements of 4th Industrial Revolution (4IR) technologies and its wide accessibility, we identified ways it can interact and make feasible a game-changing realization of such realms. We call ‘
The existing Natural knowledge is an initial condition of the system; it does not depend on any human technology. It is a source of information we inherited from evolutionary processes, occurring associated with 3.7 billion years old life on Earth. The A3W initiative targets to keep it going its course, valorizing it in many ways.
\nLearning from Nature is inherent to humans ever since we became a species (
Applying knowledge from Nature to human needs is the next natural consequence. This is the realm of invention and innovation. 4IR technologies can boost invention and prototyping of new products and solutions. More than just facilitating invention, it creates demand for new solutions, advanced materials and innovative products.
\nOnce a new biodiversity-based product or solution is developed, producing it in varying scales is the next outcome. It may utilize biodiversity inputs directly on its making or can only be sourced from biodiversity knowledge. To carryout industrial operation in the Amazon has been always a challenging, if not impossible, operation. With the changes brought by 4IR technologies and market demands, industrial equipment became smarter, lighter and customizable. It became possible to have plenty of electrical solar-powered energy in the forest, with equipment connected with satellite internet and local crews trained with virtual and augmented reality, for example. With 4IR technologies, including advanced sensors and AI, it is possible to control more precisely the use of natural resources to prevent possible negative impacts.
\nInsertion of biodiversity-originated products on a local-to-global bio-economy is a key for driving wide interest in conserving the bio-assets. Different than the traditional model of supplying commodities for further processing and generating value away from its origins, 4IR technologies and new manufacturing paradigm eases and redefines the possibilities to produce in close association with the local people on local environments, yet reaching global markets. Complicated logistic typical of a vast forest territory can be easily offset using self-flying cargo drones, for example.
\nFair sharing of socioeconomic benefits and life quality improvement for all involved, including forest stakeholders and final consumers can be levered by 4IR technologies and social changes brought by the technological revolution. With distributed ledger technologies like blockchain and holochain, we propose the creation of the Amazon BioBank. It is a framework for attributing value to many instances of Amazon socio-biodiversity. Biological assets, biomimetic insights and discoveries, traditional knowledge, local people forest skills and other sources of resources will be registered in the Amazon BioBank digital platform through holochain distributed ledger technology [64]. The Amazon BioBank share common principles with the Earth Bank of Codes [65].
\nAside from any specific technology, the ultimate, long-term result of these chain of events and realizations would be the rising of a socially shared Amazon Biome intrinsic value. The social valuing of Nature and its knowledge as an end in itself is an ideal state of relationship between humans and other elements of the natural system. By becoming acquainted and perceiving many times actual benefit from products and solution based on the Amazon biodiversity, made available by the chain of events depicted above, one can realize the value of the tropical forest. As a utilitarian value first, that over time may crystalize as core life, intrinsic value, forming the personal and social foundations to hold attitudes and behaviors that imply, support and demand conserving the Amazon Biome.
\nThe ‘innovation ecosystems’ proposed in the Amazonia Third Way initiative are creative-productive arrangements based on the Amazon 4.0 principles that synergistically align several ‘
To begin to walk down the
As results of the long-standing Program to Protect the Rainforests of Brazil (PPG-7) show, the lack of entrepreneurial skills has stood in the way of developing a non-timber bio-economy in the Amazon. Only with field-based knowledge and supporting academic curricula can tap into the Amazon’s biological and biomimetic assets, and the mainstreaming of a standing forest-flowing river, biodiversity-based bio-economy be achieved. To do that, we propose the development of a capacity program ‘Amazon Creative Labs’ (ACL). The program is designed to promote technical, technological and entrepreneurial capacity development focused on non-timber products of the Amazon biodiversity, with training events carried out directly at local communities and towns throughout Amazon region.
\nWe propose the launching of Amazon Creative Labs (ACLs)—laboratories for innovative experimentation set up throughout Amazonia. They will provide intensive training linked to local potentials to generate a virtuous insertion on bio-economy-related new opportunities. Typically, Creative Labs will be located in smaller communities, villages and towns, assembled on tents or on floating platforms packed with state-of-the-art equipment and technology for both, wide audience learning processes and core value chain local development.
\nAmazon Creative Labs will enable development of small-scale innovation ecosystems for co-design, co-development and co-creation of solutions and applications, serving as an effective interface with the knowledge and practices of the Amazon people.
\nThe Amazon Creative Labs will operationalize sustainable ‘Solution Spaces’ (see Figure 1). It is of critical importance that the Labs be community oriented, joining technology and traditional knowledge, and designed to contribute toward a strong local and regional economy.
\nThe Labs will promote capacity development activities focused on a number of products of Amazon biodiversity illustrative of an array of bio-economic and even bio-artistic applications, such as food, nutraceuticals, cosmetics, fragrances, pharmaceuticals, industrial oils, art crafts, bio-art, biomimicry, etc. Training activities can enable local communities to gather more information on the natural resources available to them, including the use of high-end technologies such as, genome sequencing.
\nThe exposure to 4IR technologies will allow innovative concepts to emerge. With the assistance of technology experts on the one hand, and entrepreneurship specialists on the other, groups of participants from Amazonian communities, villages and towns will be invited to develop new applications and to prototype (at least digitally) such innovations. The Labs’ creative environment will bring 4IR concepts like mass customization, democratized invention and smart & autonomous factories, powered by Industrial IoT, to a meaningful level with practical outcomes accessible at planned local and regional clusters of custom-sized processing and manufacturing plants.
\nAlongside communities—forest people, riverine communities and agroforestry farmers—young undergraduate or just graduated students interested in creating sustainable biodiversity-based businesses in the Amazon will be engaged. The expectation is that such ‘on the ground’ collaboration will give rise to new partnerships.
\nThe Amazon Creative Labs design includes solar photovoltaic panels, convertors and batteries, for steady power supplying, and connection to broadband satellite internet. These features will allow digital, internet-connected equipment to work for prototyping potential applications of new products and processes. These infrastructures, operating in remote regions of the Amazon, are also proof of concept of how the newest available and accessible technologies can reach and benefit the whole spectrum of the social pyramid, from their everyday life to new work opportunities.
\nACLs also include a focus on the realm of biomimetic, that is, the functions, processes and mechanisms of living organisms that, once learned, can provide insights and solutions for engineering new technologies and innovative products. They also leverage applications, including the high-end of genetic resources and genomics; prototype innovative processing of materials through the diverse links of value chains—raw materials, intermediate products, all the way to finished products.
\nTo illustrate the potential of ACLs, we designed the three following conceptual examples of applications, based on currently available technologies and equipment. A final design should incorporate new technological solutions specifically tailored for solving implementation and scaling challenges and include consultation with local communities for accessing their specific needs, priorities and potentials.
\nA line of Amazon Creative Labs will deal with value chains feed by inputs from local biodiversity and an example of that is themed after nutraceutical Cupulate, a chocolate made from the seeds of Amazon fruit Cupuaçu, instead of cacao. From forest picking to creating a final product that combines basic Cupulate with other products of very high nutritional value, the lab also includes utilizing a 3D food printer for unique chocolate designs and precise dosage of the added natural micronutrients. A by-product of Cupulate-making is cupuaçu pulp, which is then freeze-dried in a value chain of its own. Heavy-lift electric-powered drones can help overcome logistics challenges the region poses, by easily and quickly taking loads of nutraceutical cupulate sculptures and bars to a nearby gateway.
\nAnother example of ACLs focus is the Brazil Nuts value chain, known for the discrepancies between its higher cost for consumers and the low remuneration local people who harvest it from the forest receive. To change this, in one end, the ACLs will target extractivism issues, like processes precariousness that halts productivity and seeds’ price, with accessible technological resources including GIS mapping, micro-controlled sensors arrays (for health safety on seed’s harvesting and storing) and comprehensive traceability systems (origin and processes). At the same time, ACLs will carry out further locally based nut processing, using equipment that extracts oil and flour, by-products with greater trading value. With top technical education and processes precisely controlled with the aid of computers, sensors and biotechnological checks for sanitary standards, it becomes possible to output export-grade quality products strait from the forest vicinities. Those inputs also allow bringing to small villages the manufacture of even more processed products targeted to the natural cosmetics and nutraceuticals markets.
\nAnother line of ACLs will tackle the potential of making Amazon local inhabitants aware of the genetic value of biodiversity and to take part in genome sequencing projects. The lab will take participants into a knowledge journey departing from the biodiversity that can be seen all the way to the microscopic and nanoscopic structures of it, and to the grasping of the molecular coding of life. To achieve this, the Lab will make use of optical and portable electron scanning microscopes and virtual and augmented reality gear, furnished with contents to experience and understand organic chemistry complex structures. At the end, participants will carry out actual DNA sequencing through ultra-portable genome sequencers, allowing for registering genomes of species and benefiting from the provisions of benefit sharing of the Nagoya Protocol of Access and Benefit Sharing (ABS).
\nSystemic risks to the maintenance of the Amazon forest due to the synergistic combination of the main human drivers of change—namely regional climate change due to both deforestation and global warming, and augmented forest vulnerability due to fires—poses an urgent challenge to avoid an irreversible threshold being transgressed that would threaten to turn over 50% of the forest in degraded savannas in the second half of this century [2].
\nThe natural resource-intensive mode of development (the Second Way) is the dominant mode of development and receives generous government subsidies for its continued advancement. Investments in conservation, forest restoration and a sustainable economy in the global tropics of about $20 billion annually receive less than 3% of total investments. The bulk of investments (around $770 billion annually) goes to the expansion of commodities frontier of cattle, grains, oil palm [66] and also to road, energy and mining infrastructure, which are also key drivers of deforestation [67]. One more detrimental effect of such path is the increasing rural violence in the Amazon. Brazil has the highest number of assassinated rural and environmental leaders since 2015, with more than 140 killings, mostly in the Amazon [68].
\nIt is becoming crystal clear that trying to reconcile resource-intensive development with conservation is not leading to lasting and permanent solutions. Deforestation rates are still very high and do not show a tendency to go down near zero and rural violence is on the rise. Social inequalities in the Amazon remain high and are not improving at a fast pace at least to bring social indicators to the national averages of the Amazonian countries. Imposing strict conservation to protect large swathes of the forest has had clear successes over the last decades in the Amazon—about 50% of the Amazon forest is under some kind of protection. However, that in itself does not guarantee protection forever for tropical forests and eventually may affect the livelihoods of local population as is the case documented for Madagascar [69] who may bear a high cost for forest conservation.
\nThe Amazon Third Way Initiative seeks to demonstrate the urgent need for a conceptual, educational and entrepreneurial revolution—a revolution based on knowledge, traditional and scientific. The current economy of meat, grain and timber in the Brazilian Amazon is less than $10 billion a year. The economy associated to biological assets of Amazon biodiversity in a few industries (food, cosmetics, oils, etc.) is already worth 30% of that and distributes income in fairer ways and benefits more of the local population. However, that is a tiny portion of the potential of a sustainable economy hidden in the biological and biomimetic assets of Amazon biodiversity that the Amazon Third Way initiative attempts to address and give visibility to. We will be estimating the real hidden economic value of these assets in a next phase of the initiative.
\nThe Amazon forest is not a void of human presence. Diverse communities live all over the region. Even some communities of new settlers of the 1970s and 1980s have looked to find ways of generating income in agroforestry systems. There is rich traditional knowledge in many of indigenous and caboclo communities. Supporting the diversity of communities and economic pathways for a standing forest-flowing rivers economy is mandatory.
\nFrom a more general standpoint, sustainable development pathways based on natural resources exploitation should in principle put the local populations as priority. That is not the case for the Amazon currently (low HDI and other social indicators). Therefore, the Third Way Initiative also proposes that new sustainable paradigms have the development policy as a central tenet. The sustainable economy should first and utmost be means of wellbeing to the Amazonian people. That is not the case of the Second Way, where the Amazon is seen important for intensive resource exploitation for the Amazonian countries as a whole and taxation of the resource wealth should redistribute benefits as public services for all in the Amazon. However, a regressing taxation system does not realize that.
\nThe Amazon has a number of good examples of biology laboratories and a number of entrepreneurship initiatives that beyond economic development target social responsibility and deployment of sustainable biodiversity value chains. They are true pioneers into the new era of sustainability. However, they are as yet a small minority. They may even accrue national and international visibility and are role models, but in critically insufficient numbers to create momentum economically and socially to give clout to the rupture needed to put Amazon on a different track.
\nThe new model must rely on these existing good examples, on the diversities of forest communities across the Amazon, on state-of-the art knowledge generations laboratories and innovative entrepreneurship and build up from there.
\nIn due course, one has to build up momentum for enhancing the policies that are necessary to uplift the Third Way; investment in zero-deforestation value chains; reducing the enormous subsidies for commodities that drive deforestation; but as importantly invest in knowledge generation through a network of advanced biology laboratories in the Amazon, in Amazonian Countries and internationally in association with private R&D labs and science-based start-ups and creation of innovation ecosystems throughout the regions. That is a pre-requisite to the development of local next generation bio-industries in towns and cities of the future.
\nBy attracting venture capital and productive investments both for R&D and for industries, the political interest in the Third Way will rise in the eyes of governments to a tipping point in which government investments and subsidies will start to flow to this other type of economy, even on the absence of visionary governments that would see the potential of a new Amazon bio-economy and would design the pathways to reach it.
\nThe implications of harnessing the Fourth Industrial Revolution to unlock the economic value of the Amazon’s biological and biomimetic assets for governments, start-ups, corporations and R&D centers are profound. Partnerships among public and private R&D innovation labs to create a number of hubs of innovation throughout the region is necessary. This would accelerate new research and development leading to new products and innovations relevant for many industries locally and worldwide. Amazonian countries with immensely valuable natural assets would have an additional source of income to help protect these resources and support indigenous and traditional communities. These funds would create a new incentive on the part of communities and governments to protect rather than destroy natural habitats. The interest in understanding and sustainably using our biological and biomimetic assets could propel a new era of scientific exploration of life on the planet. Large new markets for sustainably sourced innovation could be created. Technology companies and start-ups seeking to demonstrate compliance with the Nagoya Protocol could be certified, through the transparency that distributed ledger technology offers.
\nIn sum, development policy in the Amazon has historically taken two pathways. The first embraces nature conservation and protects large swathes of territory from any human activity. The second approach has focused on conversion or degradation of forests for the production of agricultural commodities like meat and soya or tropical timber at the forest frontier, and also mineral commodities and the build-out of massive hydropower generation capacity. These uses together have been historically responsible for the massive deforestation of the Amazon.
\nThere is, however, a Third Way within reach in which we aggressively embrace high-tech innovation and look at the Amazon as a tremendous source of biological and biomimetic assets that can provide new, innovative products and services for current and new markets. System-level change in the Amazon as proposed cannot be executed single-handedly. On the contrary, we are proposing collaboration with leading public, private, academic and philanthropic actors for the journey ahead, engaging Indigenous and traditional communities across Amazonian countries, uniting the best capabilities of regulators, R&D centers, universities, technology start-ups and visionary companies all over the world.
\nThe Amazonia Third Way can be the most effective Land Use Change Planning policy for the Amazon because it is fully based on a standing forest-flowing river bio-economy. If successful, this new development model can be applied to all tropical regions helping to preserve the Earth’s great biological diversity. We have an important choice to make. The future of the Amazon and its impact on the planet lie so clearly in the balance. Time is not on our side, but we can still choose the Third Way.
\nThis work has been supported by the National Institute of Science and Technology for Climate Change via CNPq Grant Number 573797/2008-0 and FAPESP Grant Number 2008/57719-9 and additional financial support by the Climate and Land Use Alliance (CLUA) and Moore Foundation. We express our thanks to Juan Carlos Castilla-Rubio and Luciana Castilla for their contributions to the development of the Amazon Third Way Initiative.
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All published Book Chapters are licensed under a Creative Commons Attribution 3.0 Unported License. Monographs are licensed under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license granted to all others. Our Copyright Policy aims to guarantee that original material is published while at the same time giving significant freedom to our Authors. IntechOpen upholds a flexible Copyright Policy meaning that there is no copyright transfer to the publisher and Authors hold exclusive copyright to their work.
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He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. 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