Limits for greenhouse variables.
\r\n\t
",isbn:"978-1-80356-345-9",printIsbn:"978-1-80356-344-2",pdfIsbn:"978-1-80356-346-6",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,isNomenclature:!1,hash:"37f858c8b681abe60704245c7a1e89ee",bookSignature:"Prof. Hideki Nakano",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11832.jpg",keywords:"Basic Research, Fundamental Theory, Animal Study, Human Study, Applied Research, Clinical Application, Clinical Study, Translational Research, Advanced Technology, Robotics, Regenerative Medicine, Deep Learning",numberOfDownloads:44,numberOfWosCitations:0,numberOfCrossrefCitations:0,numberOfDimensionsCitations:0,numberOfTotalCitations:0,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"February 17th 2022",dateEndSecondStepPublish:"March 17th 2022",dateEndThirdStepPublish:"May 16th 2022",dateEndFourthStepPublish:"August 4th 2022",dateEndFifthStepPublish:"October 3rd 2022",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"4 months",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"Dr. Nakano is a pioneering researcher in neurorehabilitation and physical therapy. 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The reason to deserve this attention is due to event-based strategies reduce the exchange of information between sensors, controllers, and actuators. This reduction of information is equivalent to extend the lifetime of battery-powered wireless sensors, to reduce the computational load in embedded devices, or to cut down the network bandwidth (Miskowicz, 2005).
\n\t\t\tEvent-based systems are becoming increasingly commonplace, particularly for distributed real-time sensing and control. A characteristic application running on an event-based operating system is that where state variables are updated asynchronously in time, e.g., when an event of interest is detected or because of delays in the computation and/or communication tasks (Sandee, 2005). Event-based control systems are currently being presented as solutions to many control problems (Arzen, 1999); (Sandee, 2005); (Miskowicz, 2005); (Astrom, 2007); (Henningsson et al., 2008). In event-based control systems, it is the proper dynamic evolution of system variables what decides when the next control action will be executed, whereas in a time-based control system, the autonomous progression of the time is what triggers the execution of control actions (Astrom & Wittenmark 1997). Current distributed control systems impose restrictions on the system architecture that makes difficult the adoption of a paradigm based on events activated per time. Especially, in the case of closed-loop control using computer networks or buses, as happens with field buses, local area networks, or even Internet. An alternative to these approaches consists of using event-based controllers that are not restricted to the synchronous occurrence of controller actions. The utilization of synchronous sampling period is one of the severest conditions that control engineers impose on the software implementation. As discussed above, in an event-based control system the control actions are executed in an asynchronous way, that is, the sampling period is governed by system events and it is called event-based sampling. The event-based sampling indicates that the most appropriate method of sampling consists of transmitting information only when a significant change happens in the signal that justifies the acquisition of a new sample. Researchers have demonstrated special interest on these sampling techniques (Vasyuntynskyy & Kabitzsch, 2006); (Miskowicz, 2007); (Suh, 2007) (Dormido et al., 2008). Nowadays, commercial systems present more flexibility in the implementation of control algorithms and sampling techniques, especially WSN, where each node of the network can be programmed with a different sampling or local control algorithm with the main goal of optimizing the overall performance. This kind of solution allows control engineers to distribute the control process, considering centralized supervision of all variables, thanks to the application of wireless communications. Furthermore, remote monitoring and control through data-communication networks are very popular for process supervision and control (Banatre at al., 2008). The usage of networks provides many well-known benefits, but it also presents some limitations in the amount of transmitted data. This fact is especially visible in WSN, where the bandwidth of the communication channels is limited and typically all nodes are battery-powered. Event-based sampling techniques appear as possible solutions to face this problem allowing considerably saving of network resources and reducing the power consumption. On the other hand, the control system performance is highly affected due to the event-based sampling techniques, being necessary to analyze and study a compromise between control quality and reduction in the control signal commutations.
\n\t\t\tThe agro-alimentary sector is incorporating new technologies due to the large production demands and the diversity, quality, and market presentation requirements. A technological renovation of the sector is being required where the control engineering plays a decisive role. Automatic control and robotics techniques are incorporated in all the agricultural production levels: planting, production, harvesting and post-harvesting processes, and transportation. Modern agriculture is subjected to regulations in terms of quality and environmental impact, and thus it is a field where the application of automatic control techniques has increased substantially during last years (King & Sigrimis, 2000); (Sigrimis, 2001); (Farks, 2005); (Straten, 2007). As is well-known, greenhouses occupy very extensive surfaces where climate conditions can vary at different points (spatial distributed nature). Despite of that feature, it is very common to install only one sensor for each climatic variable in a fixed point of the greenhouse as representative of the main dynamics of the system. One of the reasons is that typical greenhouse installations require a large amount of wire to distribute sensors and actuators. Therefore, the system becomes complex and expensive and the addition of new sensors or actuators at different points in the greenhouses is thus quite limited. In the last years, WSN are becoming a convenient solution to this problem (Gonda & Cugnasca, 2006); (Narasimhan et al., 2007). A WSN is a collection of sensors and actuators nodes linked by a wireless medium to perform distributed sensing and acting tasks (Zhu et. al., 2006). The sensor nodes collect data and communicate over a network environment with a computer system, which is called base station. Based on the information collected, the base station takes decisions and then the actuator nodes perform the appropriate actions over the environment. This process allows users to sense and control the environment from anywhere (Gonda & Cugnasca, 2006). There are many situations in which the application of the WSN is preferred, for instance, environment monitoring, product quality monitoring, and others where supervision of big areas is necessary (Feng et al., 2007). In this work, WSN are used in combination with event-based systems to control the inside greenhouse climate.
\n\t\t\tControl problems in greenhouses are mainly focused on fertirrigation and climate systems. The fertirrigation control problem is usually solved providing the amount of water and fertilizers required by the crop. The climate control problem consists of keeping the greenhouse temperature and humidity in specific ranges despite of disturbances. Adaptive and feedforward controllers are commonly used for climate control problems. Therefore, fertirrigation and climate systems can be represented as event-based control problems where control actions will be calculated and performed when required by the system, for instance, when water is required by the crop or when ventilation must be closed due to changes in outside weather conditions. Furthermore, such as discussed above, with event-based control systems a new control signal is only generated when a change is detected in the system. That is, the control signal commutations are produced only when events occur. This fact is very important for the actuator life and from an economical point of view (reducing the use of electricity or fuel), especially in greenhouses where commonly actuators are composed by mechanical devices controlled by relays.
\n\t\t\tTherefore, this work presents the combination of WSN and event-based control systems to be applied in greenhouses. The main focus of this chapter is therefore the presentation of a complex real application using a WSN, as an emerging technology, and an event-based control, as a new paradigm in process control. The following issues have been addressed:
\n\t\t\tthe issues posed to a multivariable, interacting control system by possibly faulty communications (as in a wireless context),
the location of sensors to correctly represent, for the purpose of control, spatially distributed quantities,
the efficient use of actuators, the term “efficient” referring also to correct use and wear minimization,
the effects of event-based sampling.
As a first approximation, event-based control has been applied for temperature and humidity control issues. The main advantage of the proposed control problem in comparison with previous works is that promising performance results are reached reducing the use of wire and the changes of the control signals, which are translated into reductions of costs and a longer actuator life. The ideas presented in this chapter could be easily extrapolated, for instance, to building automation.
\n\t\tCrop growth is mainly influenced by the surrounding environmental climatic variables and by the amount of water and fertilizers supplied by irrigation. This is the main reason why a greenhouse is ideal for cultivation, since it constitutes a closed environment in which climatic and fertirrigation variables can be controlled to allow an optimal growth and development of the crop. The climate and the fertirrigation are two independent systems with different control problems. Empirically, the requirements of water and nutrients of different crop species are known and, in fact, the first automated systems were focused to control these variables. As the problem of greenhouse crop production is a complex issue, an extended simplification consists of supposing that plants receive the amount of water and fertilizers that they require at every moment. In this way, the problem is reduced to the control of crop growth as a function of climate environmental conditions (Rodríguez, 2002); (Rodríguez, 2008).
\n\t\t\t\tClimatic control variables.
The dynamic behaviour of the greenhouse microclimate is a combination of physical processes involving energy transfer (radiation and heat) and mass balance (water vapour fluxes and CO2 concentration). These processes depend on the external environmental conditions, structure of the greenhouse, type and state of the crop, and on the effect of the control actuators (Bot, 1983). The main ways of controlling the greenhouse climate are by using ventilation and heating to modify inside temperature and humidity conditions, shading and artificial light to change internal radiation, CO2 injection to influence photosynthesis, and fogging/misting for humidity enrichment. A deeper study about the features of the climatic control problem can be found in (Rodríguez, 2002).
\n\t\t\t\tThe approach presented in this work is applied to the climatic conditions of the mild winter in Southern Europe (the data used for the simulations performed in this work have been collected in a greenhouse located at Southeastern Spain), where the production in greenhouses is made without CO2 enrichment and the demand of quality products is increasing every day. Considering the greenhouse structures, the commonest actuators, the crop types, and the commercial conditions of this geographical area, the main climate variables to control are the temperature and the humidity. The PAR (Photosynthetically Active Radiation with a spectral range from 400 to 700 Wm2) is used by the plants as energy source in the photosynthesis process.) and it is controlled with shade screens but its use is not much extended. So, this work is focused on the temperature control problems.
\n\t\t\tPlants grow under the influence of the PAR radiation (diurnal conditions) performing the photosynthesis process. Furthermore, temperature influences the speed of sugar production by photosynthesis, and thus radiation and temperature have to be in balance in the way that a higher radiation level corresponds to a higher temperature. Hence, under diurnal conditions, it is necessary to maintain the temperature in a high level, being optimal for the photosynthesis process. In nocturnal conditions, plants are not active (the crop does not grow); therefore it is not necessary to maintain such a high temperature. For this reason, two temperature set-points are usually considered: diurnal and nocturnal (Kamp & Timmerman, 1996).
\n\t\t\t\tDue to the favorable climate conditions of Southeastern Spain, during the daytime the energy required to reach the optimal temperature is provided by the sun. In fact, the usual diurnal temperature control problem is the refrigeration of the greenhouse (with temperatures higher than the diurnal setpoint) using natural ventilation to reach the optimal diurnal temperature. On the other side, the nocturnal temperature control problem is the heating of the greenhouse (with temperatures lower than the nocturnal set-point) using heating systems to reach the nocturnal optimal temperature. In Southeastern Spain, forced-air heaters are commonly used as heating systems. In this work, the diurnal and nocturnal temperature control is analyzed to test the proposed event-based control. Therefore, typical temperature control systems with ventilation and heating are described in the following section.
\n\t\t\t\tThe natural ventilation determines the air exchange and air flow in the greenhouse as a consequence of the differences between outside and inside temperatures. The relationship between vents aperture and inside temperature is not linear (Rodríguez, 2001), but instead of using a nonlinear control schema, it was decided to implement a gain-scheduling control algorithm based on linear models for each operating point (see Figure 2). Most commercial solutions include this kind of gain scheduling controllers to cope with both fast and slow changing dynamics due to disturbances.
\n\t\t\t\tDiurnal temperature controller.
This controller consists of a gain-scheduling PI scheme where the controller parameters are changed based on some disturbances: outside temperature and wind speed. For the nocturnal temperature control, there exist many control strategies, but for this study an on/off control with dead zone is used in forced-air heaters, which is the controller commonly used in conventional greenhouses. A full description of these algorithms can be found in (Rodríguez, 2002).
\n\t\t\tAs discussed above, in an event-based control system, the control actions are executed in an asynchronous way. The event-based sampling suggests that the most appropriate method of sampling consist of transmitting information only when a significant change in the signal occurs, justifying the acquisition of a new sample. In this work, the idea is to combine WSN with event-based control (see Figure 3) such as is proposed in (Pawlowski et al., 2008).
\n\t\t\t\tEvent-based control with Wireless Sensor Network.
In this scheme, the process (a greenhouse in this case) is provided with a WSN where each sensor transmits data according to a specific sampling approach. For instance, in (Pawlowski et al., 2008), this architecture is proposed and the level crossing method is used. Therefore, in that case, each sensor will transmit data if the absolute value of the difference between the current value of the variable,
In next sections, the effect of different sampling techniques will be evaluated in the control system.
\n\t\t\tDifferent performance measurements have been used to compare the quality of the control system regarding to different event-based sampling techniques. These measurements are the following (Vasyuntynskyy & Miskowicz, 2007):
\n\t\t\t\tIAE: The Integrated Absolute Error is defined as:
IAEP: It is the difference between the system response of an event-based strategy and the system response of the time-based approach:
NE: The Number of Events is a sampling efficiency measure to compare the quality of the system response:
IAD: The integrated absolute difference is the difference between the IAE of the time-based strategy and the IAE of the event-based ones:
GPI: Global Performance Index (Vasyuntynskyy & Miskowicz, 2007) shows the compromise between the control performance and the sampling efficiency in the following way:
where
A Global Performance Index is calculated taking into account the quality of the system response and the efficiency of the sampling. The influence of sampling techniques on the performance is represented by the following factors:
\n\t\t\t\t\n\t\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
This section describes the different sampling techniques evaluated in the paper. According to the error based condition used in the sensor nodes, different event-based strategies are selected (Sánchez et al., 2009):
\n\t\t\tLC - When the difference between the current value and the last acquired value is greater than
ILC - When the value of the IAE from last acquired value is greater than
LP - When the difference between a prediction of the signal value and its current value is greater than
ILP - The integral of the difference between the prediction and the current value is greater than
EN - The energy of the difference between the current value and value of last acquired value is greater than
First and second conditions do not need a detailed explanation since both are simple well-known deadband sampling strategies. Further details on these methods can be found in (Vasyuntynskyy & Kabitzsch, 2006); (Miskowicz, 2006); (Suh, 2007). The LP method, originally described in (Suh, 2007), consists of starting the calculation of future values of the signal after an event takes place. To calculate future values, a first order predictor:
\n\t\t\tis used to estimate the evolution of the signal from last time a sample was sent to the controller. When the difference between the current value and its prediction for the current time is greater than a limit
where
Variable | \n\t\t\t\t\t\tLimit ( = 5%) | \n\t\t\t\t\t\tLimit ( = 3%) | \n\t\t\t\t\t
Inside Temperature | \n\t\t\t\t\t\t0.60 | \n\t\t\t\t\t\t0.36 | \n\t\t\t\t\t
Outside Temperature | \n\t\t\t\t\t\t0.61 | \n\t\t\t\t\t\t0.36 | \n\t\t\t\t\t
Humidity | \n\t\t\t\t\t\t4.9 | \n\t\t\t\t\t\t2.9 | \n\t\t\t\t\t
Solar Radiation | \n\t\t\t\t\t\t34.30 | \n\t\t\t\t\t\t20.58 | \n\t\t\t\t\t
Wind Speed | \n\t\t\t\t\t\t0.53 | \n\t\t\t\t\t\t0.31 | \n\t\t\t\t\t
Wind Direction | \n\t\t\t\t\t\t17.84 | \n\t\t\t\t\t\t10.70 | \n\t\t\t\t\t
Limits for greenhouse variables.
These limits of
The calculation of
To compare results between event-based sampling techniques from a data transmission point of view, the following efficiency factors have been considered:
\n\t\t\t\n\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t
The simulations presented in this section have been performed using the greenhouse climatic model developed by (Rodríguez, 2002) and the TrueTime MATLAB/Simulink toolbox. TrueTime is a tool developed for the Simulink environment and it is used to simulate real-time systems, networked control systems, communication models, and WSN (Anderson et al., 2005). The main feature of TrueTime is the possibility of co-simulation of the interaction between the real-world continuous dynamics and the computer architecture in the form of task execution and network communication. The TrueTime computer block (see Figure 4) executes user-defined tasks and interrupt handlers representing e.g. I/O tasks, control algorithms, or network drivers. The scheduling policy of the individual computer block is arbitrary and decided by the user. TrueTime allows simulation of context switching and task synchronization using events or monitors (Henriksson, 2003).
\n\t\t\tTrueTime simulation environment allows us to implement a code in C++ or Matlab programming language for every simulated node. Hence it is possible to reuse this written code for direct implementation in WSN motes. This solution decreases significantly the time necessary for the implementation of simulated ideas. One of the most relevant advantages of WSN nodes is the ability/capability to remotely reprogram selected motes.
\n\t\t\tImplementation of event-based controller with TrueTime.
Process monitoring is vitally important in companies for supervision tasks and the quality of the collected information has a great influence on the precision and accuracy of control results. Currently, the agro-alimentary market field incorporates different data acquisition techniques. Normally, the type of acquisition system is chosen to be optimal for the control algorithm to be used. In traditional climate monitoring and control systems, all sensors are distributed through the greenhouse and connected by wire to the device performing the control tasks.
\n\t\t\t\tThese equipments use time-based data sampling techniques as a consequence of using time-based controllers. In modern control systems, it is common to use communication networks to transmit data between different control system blocks. Large amount of data are usually transmitted, and the data required by the controller in each sampling time are especially critical. The most reasonable solution from an economical point of view is to make use of existing network structure, and to share the network resources between different services, for instance, using Ethernet networks. Sometimes, this solution can produce a big network traffic burden (in a typical greenhouse control system, all data are transmitted every minute or even faster) and introduce time delays in the delivery of the data packets.
\n\t\t\t\tWhen the network load increases, the probability of data losses increases too, and this factor can be very negative for control performance. In some extreme examples, the control system needs dedicated network structure to minimize the time delay and the data losses.
\n\t\t\t\tOn the other hand, the development of network structures in places with large distances, such as greenhouse installations, can become very expensive and with a complicated management. Wireless networks present an economic and useful solution to this problem, and more concretely, WSN for recording data and control purposes. However, most transceivers in WSN are battery-powered and the power consumption is a critical parameter.
\n\t\t\t\tEvery transmission means power consumption and thus these systems present the problem of limitation in the amount of data to transmit. A solution to this problem is the use of the event-based sampling techniques described in previous sections. These techniques allow that only the necessary data will be transmitted and thus only the necessary power will be consumed. In this study, WSN based on IEEE 802.15.4 ZigBee protocol has been simulated and its combination with event-based sampling in the greenhouse climatic control problem. Results of simulation were evaluated for a full crop campaign of 120 days. In this work, only eight days have been selected to present the obtained results. The limits described in Table 1 were used for the event-based sampling.
\n\t\t\t\t\n\t\t\t\t\tTable 2 presents the results obtained after simulation of the selected eight days, where the comparison of data transmission is presented for the greenhouse variables. The table compares the number of samples obtained and transmitted using event-based sampling techniques with a time-based sampling. Figure 5 shows how the events are generated from changes in the outside temperature for the LC technique.
\n\t\t\t\tOn the other hand, the variable dynamics highly affects the number of taken samples-events. This can be observed for variables with high-frequency changes such as the wind speed and direction. Figure 6 shows the transmission data for the wind direction. The transmission data from the sensors using level crossing sampling is shown on the top graphic, where a high transmission frequency is observed. However, in order to reduce the number of events created by this variable, the signal is filtered in the event generator before detecting and sending events to the controller. The bottom graphics of Figure 6 shows how the number of samples is substantially reduced after filtering the signal. However, in order to cut down the number of events created by these variables, the signals should be filtered in the sensor node before sending events to the controller.
\n\t\t\t\tVariable | \n\t\t\t\t\t\t\tIndex | \n\t\t\t\t\t\t\tTime-based | \n\t\t\t\t\t\t\tLC | \n\t\t\t\t\t\t\tILC | \n\t\t\t\t\t\t\tLP | \n\t\t\t\t\t\t\tILP | \n\t\t\t\t\t\t\tEN | \n\t\t\t\t\t\t|||||
3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t|||
Inside Temperature | \n\t\t\t\t\t\t\tSamples | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t762 | \n\t\t\t\t\t\t\t359 | \n\t\t\t\t\t\t\t2601 | \n\t\t\t\t\t\t\t1930 | \n\t\t\t\t\t\t\t1063 | \n\t\t\t\t\t\t\t534 | \n\t\t\t\t\t\t\t3212 | \n\t\t\t\t\t\t\t2389 | \n\t\t\t\t\t\t\t1042 | \n\t\t\t\t\t\t\t837 | \n\t\t\t\t\t\t
Saving | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t93,54 | \n\t\t\t\t\t\t\t96,95 | \n\t\t\t\t\t\t\t77,97 | \n\t\t\t\t\t\t\t83,65 | \n\t\t\t\t\t\t\t90,99 | \n\t\t\t\t\t\t\t95,47 | \n\t\t\t\t\t\t\t72,79 | \n\t\t\t\t\t\t\t79,76 | \n\t\t\t\t\t\t\t91,17 | \n\t\t\t\t\t\t\t92,91 | \n\t\t\t\t\t\t|
T_average | \n\t\t\t\t\t\t\t1 | \n\t\t\t\t\t\t\t15,5 | \n\t\t\t\t\t\t\t32,89 | \n\t\t\t\t\t\t\t4,54 | \n\t\t\t\t\t\t\t6,12 | \n\t\t\t\t\t\t\t11,11 | \n\t\t\t\t\t\t\t22,11 | \n\t\t\t\t\t\t\t3,68 | \n\t\t\t\t\t\t\t4,94 | \n\t\t\t\t\t\t\t11,33 | \n\t\t\t\t\t\t\t14,11 | \n\t\t\t\t\t\t|
Outside Temperature | \n\t\t\t\t\t\t\tSample | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t595 | \n\t\t\t\t\t\t\t351 | \n\t\t\t\t\t\t\t1715 | \n\t\t\t\t\t\t\t1327 | \n\t\t\t\t\t\t\t766 | \n\t\t\t\t\t\t\t517 | \n\t\t\t\t\t\t\t1846 | \n\t\t\t\t\t\t\t1432 | \n\t\t\t\t\t\t\t747 | \n\t\t\t\t\t\t\t621 | \n\t\t\t\t\t\t
Saving | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t94,96 | \n\t\t\t\t\t\t\t97,02 | \n\t\t\t\t\t\t\t85,47 | \n\t\t\t\t\t\t\t88,76 | \n\t\t\t\t\t\t\t93,51 | \n\t\t\t\t\t\t\t95,62 | \n\t\t\t\t\t\t\t84,36 | \n\t\t\t\t\t\t\t87,87 | \n\t\t\t\t\t\t\t93,6 | \n\t\t\t\t\t\t\t94,74 | \n\t\t\t\t\t\t|
T_average | \n\t\t\t\t\t\t\t1 | \n\t\t\t\t\t\t\t19,85 | \n\t\t\t\t\t\t\t33,64 | \n\t\t\t\t\t\t\t6,89 | \n\t\t\t\t\t\t\t8,9 | \n\t\t\t\t\t\t\t15,42 | \n\t\t\t\t\t\t\t22,84 | \n\t\t\t\t\t\t\t6,4 | \n\t\t\t\t\t\t\t8,25 | \n\t\t\t\t\t\t\t15,81 | \n\t\t\t\t\t\t\t19,01 | \n\t\t\t\t\t\t|
Humidity | \n\t\t\t\t\t\t\tSample | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t600 | \n\t\t\t\t\t\t\t284 | \n\t\t\t\t\t\t\t1794 | \n\t\t\t\t\t\t\t1333 | \n\t\t\t\t\t\t\t834 | \n\t\t\t\t\t\t\t409 | \n\t\t\t\t\t\t\t2193 | \n\t\t\t\t\t\t\t1615 | \n\t\t\t\t\t\t\t1246 | \n\t\t\t\t\t\t\t1026 | \n\t\t\t\t\t\t
Saving | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t94,91 | \n\t\t\t\t\t\t\t97,59 | \n\t\t\t\t\t\t\t84,80 | \n\t\t\t\t\t\t\t88,71 | \n\t\t\t\t\t\t\t92,93 | \n\t\t\t\t\t\t\t96,53 | \n\t\t\t\t\t\t\t81,42 | \n\t\t\t\t\t\t\t86,32 | \n\t\t\t\t\t\t\t89,44 | \n\t\t\t\t\t\t\t91,31 | \n\t\t\t\t\t\t|
T_average | \n\t\t\t\t\t\t\t1 | \n\t\t\t\t\t\t\t19,68 | \n\t\t\t\t\t\t\t41,58 | \n\t\t\t\t\t\t\t6,58 | \n\t\t\t\t\t\t\t8,86 | \n\t\t\t\t\t\t\t14,16 | \n\t\t\t\t\t\t\t28,87 | \n\t\t\t\t\t\t\t5,38 | \n\t\t\t\t\t\t\t7,31 | \n\t\t\t\t\t\t\t9,48 | \n\t\t\t\t\t\t\t11,51 | \n\t\t\t\t\t\t|
Solar Radiation | \n\t\t\t\t\t\t\tSample | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t826 | \n\t\t\t\t\t\t\t553 | \n\t\t\t\t\t\t\t1885 | \n\t\t\t\t\t\t\t1464 | \n\t\t\t\t\t\t\t1006 | \n\t\t\t\t\t\t\t754 | \n\t\t\t\t\t\t\t2244 | \n\t\t\t\t\t\t\t1754 | \n\t\t\t\t\t\t\t3170 | \n\t\t\t\t\t\t\t2728 | \n\t\t\t\t\t\t
Saving | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t93,00 | \n\t\t\t\t\t\t\t95,31 | \n\t\t\t\t\t\t\t84,03 | \n\t\t\t\t\t\t\t87,60 | \n\t\t\t\t\t\t\t91,48 | \n\t\t\t\t\t\t\t93,61 | \n\t\t\t\t\t\t\t80,99 | \n\t\t\t\t\t\t\t85,14 | \n\t\t\t\t\t\t\t73,15 | \n\t\t\t\t\t\t\t76,89 | \n\t\t\t\t\t\t|
T_average | \n\t\t\t\t\t\t\t1 | \n\t\t\t\t\t\t\t14,3 | \n\t\t\t\t\t\t\t21,35 | \n\t\t\t\t\t\t\t6,26 | \n\t\t\t\t\t\t\t8,07 | \n\t\t\t\t\t\t\t11,74 | \n\t\t\t\t\t\t\t15,66 | \n\t\t\t\t\t\t\t5,26 | \n\t\t\t\t\t\t\t6,73 | \n\t\t\t\t\t\t\t3,72 | \n\t\t\t\t\t\t\t4,33 | \n\t\t\t\t\t\t|
Wind Speed | \n\t\t\t\t\t\t\tSample | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t802 | \n\t\t\t\t\t\t\t386 | \n\t\t\t\t\t\t\t2569 | \n\t\t\t\t\t\t\t1890 | \n\t\t\t\t\t\t\t1024 | \n\t\t\t\t\t\t\t557 | \n\t\t\t\t\t\t\t3070 | \n\t\t\t\t\t\t\t2318 | \n\t\t\t\t\t\t\t1015 | \n\t\t\t\t\t\t\t802 | \n\t\t\t\t\t\t
Saving | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t93,20 | \n\t\t\t\t\t\t\t96,73 | \n\t\t\t\t\t\t\t78,24 | \n\t\t\t\t\t\t\t83,99 | \n\t\t\t\t\t\t\t91,32 | \n\t\t\t\t\t\t\t95,28 | \n\t\t\t\t\t\t\t74,00 | \n\t\t\t\t\t\t\t80,36 | \n\t\t\t\t\t\t\t91,40 | \n\t\t\t\t\t\t\t93,20 | \n\t\t\t\t\t\t|
T_average | \n\t\t\t\t\t\t\t1 | \n\t\t\t\t\t\t\t14,72 | \n\t\t\t\t\t\t\t30,59 | \n\t\t\t\t\t\t\t4,6 | \n\t\t\t\t\t\t\t6,25 | \n\t\t\t\t\t\t\t11,53 | \n\t\t\t\t\t\t\t21,2 | \n\t\t\t\t\t\t\t3,85 | \n\t\t\t\t\t\t\t5,09 | \n\t\t\t\t\t\t\t11,63 | \n\t\t\t\t\t\t\t14,72 | \n\t\t\t\t\t\t|
Wind Direction | \n\t\t\t\t\t\t\tSample | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t1707 | \n\t\t\t\t\t\t\t993 | \n\t\t\t\t\t\t\t3410 | \n\t\t\t\t\t\t\t2489 | \n\t\t\t\t\t\t\t2006 | \n\t\t\t\t\t\t\t1162 | \n\t\t\t\t\t\t\t3907 | \n\t\t\t\t\t\t\t2989 | \n\t\t\t\t\t\t\t5276 | \n\t\t\t\t\t\t\t4607 | \n\t\t\t\t\t\t
Saving | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t85,54 | \n\t\t\t\t\t\t\t91,59 | \n\t\t\t\t\t\t\t71,12 | \n\t\t\t\t\t\t\t78,92 | \n\t\t\t\t\t\t\t83,01 | \n\t\t\t\t\t\t\t90,15 | \n\t\t\t\t\t\t\t66,91 | \n\t\t\t\t\t\t\t74,68 | \n\t\t\t\t\t\t\t55,31 | \n\t\t\t\t\t\t\t60,98 | \n\t\t\t\t\t\t|
T_average | \n\t\t\t\t\t\t\t1 | \n\t\t\t\t\t\t\t6,92 | \n\t\t\t\t\t\t\t11,89 | \n\t\t\t\t\t\t\t3,46 | \n\t\t\t\t\t\t\t4,74 | \n\t\t\t\t\t\t\t5,89 | \n\t\t\t\t\t\t\t10,16 | \n\t\t\t\t\t\t\t3,02 | \n\t\t\t\t\t\t\t3,95 | \n\t\t\t\t\t\t\t2,24 | \n\t\t\t\t\t\t\t2,56 | \n\t\t\t\t\t\t|
\n\t\t\t\t\t\t\t | Average saving [%] | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t92,53 | \n\t\t\t\t\t\t\t95,87 | \n\t\t\t\t\t\t\t80,27 | \n\t\t\t\t\t\t\t85,27 | \n\t\t\t\t\t\t\t90,54 | \n\t\t\t\t\t\t\t94,44 | \n\t\t\t\t\t\t\t76,75 | \n\t\t\t\t\t\t\t82,36 | \n\t\t\t\t\t\t\t82,36 | \n\t\t\t\t\t\t\t85,00 | \n\t\t\t\t\t\t
Comparison of sampling techniques.
As it can be seen, the number of events is smaller for
Event generation for outside temperature.
Signal with high frequency dynamics.
The biggest saving is obtained for the LC and LP techniques with
So, it is clear that the number of samples depends on two factors: the limit
Signal tracking for event-based sampling techniques.
Influence of
This section presents the simulation results obtained for the greenhouse climatic control problem. The control system works as described in Figure 3, where the controller calculates a new control signal when an event happens. The LC and LP techniques incorporate the additional condition (12) to guarantee event generation in steady state situations. The event triggering is governed by an event generator that detects the possible events affecting the controller. For this simulation study, these events are represented by changes on: set-point, inside temperature, outside temperature, and wind speed.
\n\t\t\t\tThe events are generated when the controller node receives a data packet, and produces a new action from the PI control task. If the new value of the control signal is different from the value sent last time, a new transmission to actuator node is performed. As discussed above, only eight selected days have been used as representative of the simulation study. The temperature set-point (SP) was set at 26 oC and 17 oC for diurnal and nocturnal periods, respectively. Figure 9 and 10 presents the simulation results for a two-day diurnal period with the purpose of showing up the influence of event-based controllers. These Figures compare a time-based controller (TB) and an event-based controller (EB) for each different sampling method and with
Index | \n\t\t\t\t\t\t\tTime-based | \n\t\t\t\t\t\t\tLC | \n\t\t\t\t\t\t\tILC | \n\t\t\t\t\t\t\tLP | \n\t\t\t\t\t\t\tILP | \n\t\t\t\t\t\t\tEN | \n\t\t\t\t\t\t|||||
3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t||
IAE | \n\t\t\t\t\t\t\t134.91 | \n\t\t\t\t\t\t\t135.88 | \n\t\t\t\t\t\t\t152.96 | \n\t\t\t\t\t\t\t124.03 | \n\t\t\t\t\t\t\t136.31 | \n\t\t\t\t\t\t\t149.72 | \n\t\t\t\t\t\t\t162.87 | \n\t\t\t\t\t\t\t124.46 | \n\t\t\t\t\t\t\t126.64 | \n\t\t\t\t\t\t\t134.18 | \n\t\t\t\t\t\t\t135.45 | \n\t\t\t\t\t\t
IAEP | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t65.18 | \n\t\t\t\t\t\t\t87.69 | \n\t\t\t\t\t\t\t37.59 | \n\t\t\t\t\t\t\t31.97 | \n\t\t\t\t\t\t\t64.43 | \n\t\t\t\t\t\t\t84.99 | \n\t\t\t\t\t\t\t31.82 | \n\t\t\t\t\t\t\t35.06 | \n\t\t\t\t\t\t\t31.28 | \n\t\t\t\t\t\t\t67.51 | \n\t\t\t\t\t\t
NE | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t0.479 | \n\t\t\t\t\t\t\t0.561 | \n\t\t\t\t\t\t\t0.303 | \n\t\t\t\t\t\t\t0.234 | \n\t\t\t\t\t\t\t0.430 | \n\t\t\t\t\t\t\t0.521 | \n\t\t\t\t\t\t\t0.255 | \n\t\t\t\t\t\t\t0.276 | \n\t\t\t\t\t\t\t0.233 | \n\t\t\t\t\t\t\t0.498 | \n\t\t\t\t\t\t
IAD | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t0.965 | \n\t\t\t\t\t\t\t21.40 | \n\t\t\t\t\t\t\t10.87 | \n\t\t\t\t\t\t\t1.40 | \n\t\t\t\t\t\t\t14.81 | \n\t\t\t\t\t\t\t27.95 | \n\t\t\t\t\t\t\t10.45 | \n\t\t\t\t\t\t\t8.26 | \n\t\t\t\t\t\t\t0.729 | \n\t\t\t\t\t\t\t0.543 | \n\t\t\t\t\t\t
GPI | \n\t\t\t\t\t\t\t24155 | \n\t\t\t\t\t\t\t4379,4 | \n\t\t\t\t\t\t\t2169,5 | \n\t\t\t\t\t\t\t13860,3 | \n\t\t\t\t\t\t\t10368,2 | \n\t\t\t\t\t\t\t5775,4 | \n\t\t\t\t\t\t\t3265,5 | \n\t\t\t\t\t\t\t16351,2 | \n\t\t\t\t\t\t\t12360,2 | \n\t\t\t\t\t\t\t5662,2 | \n\t\t\t\t\t\t\t4598,4 | \n\t\t\t\t\t\t
Calls | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t2159 | \n\t\t\t\t\t\t\t1060 | \n\t\t\t\t\t\t\t6885 | \n\t\t\t\t\t\t\t5145 | \n\t\t\t\t\t\t\t2853 | \n\t\t\t\t\t\t\t1608 | \n\t\t\t\t\t\t\t8128 | \n\t\t\t\t\t\t\t6139 | \n\t\t\t\t\t\t\t2786 | \n\t\t\t\t\t\t\t2260 | \n\t\t\t\t\t\t
Sending | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t2159 | \n\t\t\t\t\t\t\t1060 | \n\t\t\t\t\t\t\t6885 | \n\t\t\t\t\t\t\t5145 | \n\t\t\t\t\t\t\t2853 | \n\t\t\t\t\t\t\t1608 | \n\t\t\t\t\t\t\t8128 | \n\t\t\t\t\t\t\t6139 | \n\t\t\t\t\t\t\t2786 | \n\t\t\t\t\t\t\t2260 | \n\t\t\t\t\t\t
Actions | \n\t\t\t\t\t\t\t539 | \n\t\t\t\t\t\t\t61 | \n\t\t\t\t\t\t\t49 | \n\t\t\t\t\t\t\t90 | \n\t\t\t\t\t\t\t78 | \n\t\t\t\t\t\t\t69 | \n\t\t\t\t\t\t\t49 | \n\t\t\t\t\t\t\t95 | \n\t\t\t\t\t\t\t82 | \n\t\t\t\t\t\t\t90 | \n\t\t\t\t\t\t\t78 | \n\t\t\t\t\t\t
Control performance indexes for the diurnal period.
Index | \n\t\t\t\t\t\t\tTime-based | \n\t\t\t\t\t\t\tLC | \n\t\t\t\t\t\t\tILC | \n\t\t\t\t\t\t\tLP | \n\t\t\t\t\t\t\tILP | \n\t\t\t\t\t\t\tEN | \n\t\t\t\t\t\t|||||
3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t\t3% | \n\t\t\t\t\t\t\t5% | \n\t\t\t\t\t\t||
IAE | \n\t\t\t\t\t\t\t239.72 | \n\t\t\t\t\t\t\t881.19 | \n\t\t\t\t\t\t\t1472.9 | \n\t\t\t\t\t\t\t453.04 | \n\t\t\t\t\t\t\t568.8 | \n\t\t\t\t\t\t\t933.69 | \n\t\t\t\t\t\t\t1421.7 | \n\t\t\t\t\t\t\t388.72 | \n\t\t\t\t\t\t\t493.1943 | \n\t\t\t\t\t\t\t830.97 | \n\t\t\t\t\t\t\t943.4 | \n\t\t\t\t\t\t
IAEP | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t840.54 | \n\t\t\t\t\t\t\t1401.6 | \n\t\t\t\t\t\t\t425.29 | \n\t\t\t\t\t\t\t535.3 | \n\t\t\t\t\t\t\t892.32 | \n\t\t\t\t\t\t\t1365.0 | \n\t\t\t\t\t\t\t385.52 | \n\t\t\t\t\t\t\t477.5 | \n\t\t\t\t\t\t\t786.79 | \n\t\t\t\t\t\t\t899.5 | \n\t\t\t\t\t\t
NE | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t0.953 | \n\t\t\t\t\t\t\t0.951 | \n\t\t\t\t\t\t\t0.938 | \n\t\t\t\t\t\t\t0.941 | \n\t\t\t\t\t\t\t0.955 | \n\t\t\t\t\t\t\t0.960 | \n\t\t\t\t\t\t\t0.991 | \n\t\t\t\t\t\t\t0.968 | \n\t\t\t\t\t\t\t0.946 | \n\t\t\t\t\t\t\t0.953 | \n\t\t\t\t\t\t
IAD | \n\t\t\t\t\t\t\t0 | \n\t\t\t\t\t\t\t641.47 | \n\t\t\t\t\t\t\t1233.2 | \n\t\t\t\t\t\t\t213.32 | \n\t\t\t\t\t\t\t329.1 | \n\t\t\t\t\t\t\t693.97 | \n\t\t\t\t\t\t\t1182.0 | \n\t\t\t\t\t\t\t149.00 | \n\t\t\t\t\t\t\t253.4 | \n\t\t\t\t\t\t\t591.24 | \n\t\t\t\t\t\t\t703.7 | \n\t\t\t\t\t\t
GPI | \n\t\t\t\t\t\t\t27045 | \n\t\t\t\t\t\t\t5140,9 | \n\t\t\t\t\t\t\t2622,9 | \n\t\t\t\t\t\t\t15550,9 | \n\t\t\t\t\t\t\t11672,9 | \n\t\t\t\t\t\t\t6568,9 | \n\t\t\t\t\t\t\t3772,9 | \n\t\t\t\t\t\t\t18323,9 | \n\t\t\t\t\t\t\t13942,9 | \n\t\t\t\t\t\t\t7352,9 | \n\t\t\t\t\t\t\t5902,9 | \n\t\t\t\t\t\t
Calls | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t2159 | \n\t\t\t\t\t\t\t1060 | \n\t\t\t\t\t\t\t6885 | \n\t\t\t\t\t\t\t5145 | \n\t\t\t\t\t\t\t2853 | \n\t\t\t\t\t\t\t1608 | \n\t\t\t\t\t\t\t8128 | \n\t\t\t\t\t\t\t6139 | \n\t\t\t\t\t\t\t2786 | \n\t\t\t\t\t\t\t2260 | \n\t\t\t\t\t\t
Sending | \n\t\t\t\t\t\t\t11808 | \n\t\t\t\t\t\t\t2159 | \n\t\t\t\t\t\t\t1060 | \n\t\t\t\t\t\t\t6885 | \n\t\t\t\t\t\t\t5145 | \n\t\t\t\t\t\t\t2853 | \n\t\t\t\t\t\t\t1608 | \n\t\t\t\t\t\t\t8128 | \n\t\t\t\t\t\t\t6139 | \n\t\t\t\t\t\t\t2786 | \n\t\t\t\t\t\t\t2260 | \n\t\t\t\t\t\t
Actions | \n\t\t\t\t\t\t\t3429 | \n\t\t\t\t\t\t\t822 | \n\t\t\t\t\t\t\t502 | \n\t\t\t\t\t\t\t1780 | \n\t\t\t\t\t\t\t1382 | \n\t\t\t\t\t\t\t862 | \n\t\t\t\t\t\t\t556 | \n\t\t\t\t\t\t\t2067 | \n\t\t\t\t\t\t\t1664 | \n\t\t\t\t\t\t\t1780 | \n\t\t\t\t\t\t\t1382 | \n\t\t\t\t\t\t
Control performance indexes for the nocturnal period.
The results of GPI were better for event-based controllers with
Control results for a two-hour diurnal period – example 1.
Control results for a two-hour diurnal period– example 2.
Control performance indexes for diurnal period.
The lowest number of commutations is produced by the EB-LC and EB-LP cases, but their errors are bigger in comparison with the other event-based controllers. Table 4 accumulates results of control performance for nocturnal period. Figure 14 shows the full list of control performance indexes for the nocturnal period. The IAE values confirm that the control quality is worst for event-based controllers and only the EB-ILP and EB-ILC obtain magnitudes approximated to the TB one.
\n\t\t\t\tControl results for a twelve-hour nocturnal period – example 1.
Control results for a twelve-hour nocturnal period – example 2.
Control performance indexes for the nocturnal period.
The consequence of this fact is the high number of transmissions between the different blocks in the control system. The analysis of the GPI index shows that EB-LC, EB-LP, and EB-EN present similar results. However, the EB-EN controller keeps reduced the transmissions without a relevant increase of the IAE in comparison to the other event-based controllers.
\n\t\t\tThis paper presents a study of event-based sampling techniques and their application to the greenhouse climate control problem. It was possible to obtain important information about data transmission and control performance for all techniques. As conclusion, it was deduced that the data rate can be set up to obtain a compromise between control performance and number of transmissions, where results for different values of
This work has been supported by the Spanish CICYT under DPI2007-66718-C04-04 and DPI2007-61068 grants.
\n\t\tInvestigating students’ in-depth understanding, mainly their unscientific knowledge, has been carried out for decades. Teachers’ knowledge of students’ understanding, including their prior knowledge or preconception and understanding after teaching, is valuable. Knowledge regarding students’ preconceptions is essential in assisting educators in providing effective teaching and learning. Many studies have proved the contribution of students’ prior knowledge to their teaching success [1, 2]. Several instruments have been used for uncovering students’ conception in science, including concept mapping [3], interviews [4], and the multiple-choice test [5, 6]. A proper and effective instrument must be utilized to investigate students’ understanding. A typical instrument such as a multiple-choice question (MCQ) cannot uncover a deep understanding [7] in science, particularly students’ unscientific understanding/misconceptions. It has been revealed that the previous instruments have some disadvantages. Concept mapping relies on students’ ability to master vocabulary [8], while the interview is time-consuming [9]. For multiple-choice questions, students’ test-wiseness skills [10] could affect their reliability and validity indices, and the reason for students’ answers cannot be fully uncovered [11]. Also, the role of guessing is often dominant in a multiple choice question [12].
Due to those previous instruments’ disadvantages, the multi-tier format’s diagnostic tool has recently been one of the most frequent instruments applied in science education studies. Our previous study [13] investigated the instrument used in the study involving students’ understanding of chemistry and other science disciplines (biology and physics) covered in Indonesian journals. We revealed that multi-tier instruments, particularly four-tier instruments, have been the most accepted instrument and widely applied by Indonesian researchers in identifying students’ unscientific understanding.
In this paper, several terminologies, including students’ conception, students’ understanding, students’ scientific understanding, students’ scientific knowledge, students’ unscientific understanding, and misconceptions, are found. Students’ conception reflects students’ ideas and mental processes regarding natural phenomena. The ideas could be relevant or irrelevant to the concept accepted by the scientific community [14]. For this reason, the terminology of students’ conception and students’ understanding are interchangeable in this paper. The ideas which adhere to the concept accepted by the scientific community are called scientific knowledge. In contrast, those different from a view taken by the scientific community are called unscientific understanding.
The incorrect idea harbored by any particular person has been described in several different terminologies in the scientific literature, including wrong knowledge, misconception, erroneous ideas, unscientific understanding, alternative conception, misunderstanding, erroneous concepts, naïve idea, alternative frameworks, naïve concept, misinterpretation, and oversimplifications. Although these terms are interchangeable, the “unscientific understanding” is preferred in this paper because it reflects the nature of students’ incorrect ideas or concepts.
The use of multi-tier instruments in science education was initiated by Treagust [15], investigating students’ unscientific understanding in particular. The example of the two-tier instrument applied in such an instrument’s initial development is provided in Figure 1.
Example of the two-tier instrument developed by Treagust [
The first-tier at the initial format portrayed in Figure 1 consists of a multiple-choice question (MCQ) with only two options (one correct answer and one incorrect answer). This MCQ with a two-options format is quite uncommonly applied in science assessment, common in at least four options. The second tier consists of four statements covering the reasons for students’ answers to the first-tier. The four reasons consist of one valid or scientific reason and three wrong or unscientific reasons. The combination of students’ incorrect answers and the incorrect reason is the basis for revealing students’ unscientific understanding or misconception. All incorrect reasons in the reason tier are composed based on students’ actual unscientific understanding obtained from preliminary tests, interviews, and literature. The next generation of the two-tier instrument has employed a more standard MCQ in the first-tier, as depicted in Figure 2.
Example of the next generation of the two-tier instrument developed by Chandrasegaran et al. [
This two-tier format has been applied to investigate students’ conception in many science education research including Tan et al. [16] in inorganic chemistry, Tuysuz [17] in Separation of Matter, Griffard & Wandersee [18] in Photosynthesis, Chandrasegaran et al. [9] in Chemical reaction, Peterson et al. [5] in covalent bonding, Tyson et al. [19] in chemical equilibrium, Adadan & Savasci [20] in solution chemistry and many others.
After being applied in many studies, science education researchers realized that the two-tier instrument has deficiencies. Students selected the correct answer and correct reason randomly without holding a scientific reason to the relevant concept on certain occasions. The role of guessing and the actual unscientific understanding are difficult to be differentiated in a two-tier instrument [21, 22].
To overcome the two-tier instrument’s drawback, a three-tier instrument was developed with the additional confidence rating tier, as shown in Figure 3. The third-tier requires students to state whether they are sure or unsure of their answer and reason. A correct answer and reason with a sure expression imply a scientific understanding. Meanwhile, an incorrect answer and reason with a sure expression imply an unscientific understanding or misconception. An incorrect answer and reason with an unsure expression imply that the incorrect answer is not a result of misconception or unscientific understanding; instead, it lacks knowledge or guessing. This aspect distinguishes the three-tier format and the previous format. The same pattern of the three-tier instrument portrayed in Figure 3 has been used in the following studies [11, 24, 25].
Example of a three-tier instrument developed by Arslan et al. [
The subsequent development of a three-tier instrument utilized a more flexible confidence rating with a broader range of confidence, as displayed in Figure 4. This pattern seems to have been influenced by the standard confidence rating scales applied in many four-tier instruments that had been published before this three-tier work was carried out.
Example of a three-tier instrument developed by Aydeniz et al. [
The confidence rating index (CRI), which is only attached to the third tier of the three-tier instrument, leads to an unclear message whether students have the same or different confidence levels between their answer and their reason [23]. For this reason, many science education researchers developed and applied the four-tier instrument. The first-tier, called Answer-tier (A-tier), consists of MCQ with several options (commonly 4). The second tier is the confidence rating for the A-tier. The third-tier, which is called Reason-tier (R-tier), consists of several statements with one correct statement relevant to the selected answer and several unscientific statements. The fourth-tier is the confidence rating for the R-tier.
The confidence rating index (CRI) for A-tier and R-tier ranged from 1 (just guessing) to 6 (absolutely confident). This more comprehensive range was then adopted for some studies that utilize three-tier instruments, as shown in Figure 4. In our recent works [7], we prefer to apply five scales of confidence rating instead of 6 scales (Figure 5).
Example of four-tier instrument with six confidence ratings [
Using five scales of CRI provides better clarity in differentiating students’ level of confidence ratings. For example, the difference between ‘confident’ [4], ‘very confident’ [5], and ‘absolutely confident’ [6] in a six scales CRI format is quite challenging to be recognized. However, ‘quite confident’ [4] and ‘very confidents’ [5] in 5 scales format is more comfortable to be understood. When a student is 100% sure of his/her answer, he/she will state very confident. Meanwhile, when he/she is not 100% sure of his/her answer, he/she will state quite confident. ‘Average’ [3] is used to express an equal portion of sure and unsure, which is not available in the six scales format. ‘Very unconfident’ [1] is used to express 100% unsure, including guessing or absolutely no knowledge regarding the concept. While ‘not very confident’ [2] is used to express an unsure reason with a small portion of feeling that his/her answer may be correct. For this reason, we suggest using five scales of CRI instead of 6 scales (Figure 6).
Example of four-tier instrument in chemical kinetics with five confidence ratings [
The current development of a multi-tier instrument is a five-tier instrument published by Anam et al. [28], with the additional fifth tier in which students are required to provide a draw/pictorial representation of his/her answer. This additional drawing will ensure the mental model of the students can be uncovered. Even though the work in a five-tier instrument is still limited, we believe that it offers a more powerful tool in this regard. A pictorial tool is supported by psychology cognitive theory that helps students solve a multistep task [29].
Treagust [15] proposed the two-tier instrument development is the fundamental development of the next generations of multi-tier instruments, including three-tier and four-tier instruments. Treagust [15] employed ten steps with three board categories in developing a two-tier instrument. The first four steps are named
Identifying proportional knowledge statements
Developing a concept map
Relating proportional knowledge to the concept map
Validating the content
Examining related literature
Conducting unstructured student interviews
Developing multiple-choice questions with free responses
Developing the two-tier diagnostic tests
Designing a specification grid
Continuing refinements
When we developed a four-tier instrument in the area of chemical kinetics named FTDICK [7], we simplified the procedure to be six steps as the following. This procedure is applicable to developing multi-tier instruments.
In this step, several essential concepts in a particular topic are identified concerning the concept’s scope in the relevant curriculum. For example, when we developed a four-tier instrument to identify secondary school students’ understanding of thermochemistry, the competence mastery indicator document (Indikator Pencapaian Kompetensi, IPK) in the syllabus for Indonesian chemistry secondary school was considered. System and surrounding, enthalpy, exothermic reaction, and endothermic reaction are essential concepts in the Indonesian curriculum. When we developed a four-tier instrument of chemical kinetics for first-year chemistry students, university students’ chemistry curriculum was considered. Rate law, the relation between reactant concentration and time, temperature and rate, activation energy, and reaction mechanisms are essential concepts for first-year university students.
Each essential concept should be represented by two or more questions to ensure that it reflects all the competence and knowledge that should be mastered at the concept. Figure 7 below depicts an example of MCQ-FR in the concept of chemical kinetics, particularly rate law and the relation of concentration and rate.
Example of MCQ-FR in chemical kinetics.
Before it is used to collect the preliminary data, the content of MCQ-FR, the relevance with curriculum, and language clarity are assessed to get feedback from some experts in the field. This feedback will be the basis to revise the MCQ-FR.
The revised MCQ-FR is then used to collect preliminary data, which are students’ unscientific understanding or illogical reasons. For example, in answering the question in Figure 7, some students believed that
A significant number of students should demonstrate students’ unscientific understanding used as a reason option. Students’ responses in this step are also used to measure the MCQ-FR quality in terms of validity, reliability, distractor effectiveness, discriminatory index, and difficulty level. The unscientific understanding above is utilized as the optional reason at the multi-tier instrument (Figure 6, Reason B).
The next step is testing the prototype multi-tier instruments to a group of students to measure its validity, reliability, distractor effectiveness, discriminatory index, and difficulty level (5 parameters). This step is also named empirical validity. Please refers to the educational evaluation and measurement references to find out the formulae to calculate these parameters. The analysis of the five parameters’ values is the basis for revising the prototype and producing the final multi-tier instrument, which applies to the broader community.
Students’ responses to the multi-tier questions provide four types of combinations of students’ answers and reasons, namely: Correct Answer and Correct Reason (CACR) representing good scientific understanding; Correct Answer and Wrong Reason (CAWR) representing a false positive of students’ unscientific understanding; Wrong Answer and Correct Reason (WACR) representing a false negative of students’ unscientific understanding. These three categories are not discussed widely in this paper. Wrong Answer and Wrong Reason (WAWR) represents an actual student’s unscientific understanding. This WAWR is the central aspect discussed in this regard and the prime category to be used in interpreting students’ unscientific understanding.
Students’ unscientific understanding is determined based on students’ WAWR combinations. Several parameters and terminologies have been used to determine the level of students’ unscientific understanding based on the students’ confidence ratings or confidence rating index (CRI) of WAWR. Caleon & Subramaniam [21] employed six scales of confidence ratings and classified unscientific understanding or misconception as to the following. A
The use of this parameter with a decimal number (3.5 as the limit) raises a critique considering that all the CRI scales are in whole numbers. Therefore, the rationale to use the decimal limit is questionable. For this reason, we suggest using the following parameter to classify students’ unscientific understanding for a multi-tier instrument that employs five scales of CRI (Table 1).
CRI | Category |
---|---|
≥ 3 | |
3–4: | |
≥ 4: | |
< 3 |
The parameter to classify unscientific understanding for 5 CRI scales.
The example of how to determine students’ unscientific understanding is provided from our work in the area of thermochemistry, which is in the press for publication elsewhere. The question in Figure 8 was intended to investigate students’ understanding of the system and surroundings, particularly the difference between open, closed, and isolated systems.
Example of a four-tier instrument in thermochemistry [
In answering the question in Figure 8 above, 34.43% of students demonstrated an unscientific understanding that the
This section will present our current study in this area involving the development of a four-tier instrument in the topic of electrolyte and non-electrolyte solution. The instrument that was produced in this study is named the Four-Tier Instrument of Electrolyte and Non-Electrolyte Solution (FTI-ENES).
This research employed the procedure proposed by Habiddin & Page [7] with six steps, as explained in Section 3 above. In the first step (mapping concept), it was found that differentiating electrolyte solution and non-electrolyte solution based on its electrical conductivity is the essential concept for a secondary school in Indonesia. The essential concept covers three indicators of competencies, including [1] identifying the electrical conductivity of the solution of an ionic compound, [2] identifying the electrical conductivity of the solution of covalent compound, [3] identifying the electrical conductivity of the solution of the polar covalent compound.
Next, several 22 MCQ-FR questions were constructed and intended to measure students’ unscientific understanding regarding the three indicators. The example of a question in the MCQ-FR is presented in Figure 9. The questions were assessed in term of the scope of chemistry content and clarity in the language before being used for data collection by the chemistry lecturer and school teacher. The suggestions and feedbacks obtained were the basis for improving or revising the MCQ-FR.
Example of a four-tier instrument in electrolyte and non-electrolyte solution.
In this study, the questions were focused on the conceptual type of question and avoided the algorithmic type. The initial data collection was carried out and involved five groups of students (153 in total) from two public secondary schools in Malang, East Java, Indonesia. Two groups from SMA Negeri 3 Malang (Public secondary school 3 in Malang) and three groups from SMA Negeri 8 Malang (Public secondary school 8) had taken the subject of electrolyte and non-electrolyte solutions.
Students’ responses to the MCQ-FR of electrolyte and non-electrolyte solutions were categorized into scientific responses, unscientific responses and random responses. The unscientific responses were the basis to produce the FTI-ENES with 13 questions that experienced content validity afterwards. Next, the FTI-ENES was validated empirically involving two groups of students (62 in total) from SMAN 2 Ponorogo, East Java, Indonesia (Public secondary school 2 in Ponorogo). The parameters used in the empirical validation, including reliability, validity, difficulty level, discriminatory index and distractor effectiveness. Based on these parameters’ values, improvements/revisions were made to refine the FTI-ENES and produce the final version of FTI-ENES.
In the initial data collection, several students’ unscientific understanding were uncovered using the MCQ-FR. Some examples of students’ unscientific understanding that C12H22O11(
Example of a four-tier instrument in the FTI-ENES.
The quality of the FTI-ENES is primarily reflected based on the values of 2 parameters, including validity and reliability. The two parameters are the most valuable aspect in assessing the quality of a question [31]. The last three parameters, including difficulty level, discriminatory index, and distractor effectiveness, are also essential, particularly formative and summative tests.
All the questions of the FTI-ENES instrument are valid with high validity indices. The average validity index for A-tier, R-tier and B-tier are 0.46, 0.45 and 0.53, respectively. These values confirm that the FTI-ENES is powerful for identifying students’ unscientific understanding in the area of electrolyte and non-electrolyte solutions. The detail values for each question and each tier are provided in Table 2.
Question | Answer-tier (A-tier) | Reason-tier (R tier) | Both tier (B tier) | |||
---|---|---|---|---|---|---|
r | Category | r | Category | r | Category | |
1. | 0.696 | Valid | 0.500 | Valid | 0.611 | Valid |
2. | 0.495 | Valid | 0.372 | Valid | 0.564 | Valid |
3. | 0.469 | Valid | 0.523 | Valid | 0.532 | Valid |
4. | 0.524 | Valid | 0.404 | Valid | 0.644 | Valid |
5. | 0.506 | Valid | 0.451 | Valid | 0.459 | Valid |
6. | 0.455 | Valid | 0.485 | Valid | 0.515 | Valid |
7. | 0.407 | Valid | 0.496 | Valid | 0.582 | Valid |
8. | 0.339 | Valid | 0.357 | Valid | 0.455 | Valid |
9. | 0.456 | Valid | 0.522 | Valid | 0.473 | Valid |
10. | 0.592 | Valid | 0.583 | Valid | 0.697 | Valid |
11. | 0.346 | Valid | 0.252 | Valid | 0.366 | Valid |
12. | 0.265 | Valid | 0.513 | Valid | 0.514 | Valid |
13. | 0.453 | Valid | 0.317 | Valid | 0.422 | Valid |
Validity indices of the FTI-ENES.
The reliability index of the FTI-ENES was measured using the technic of Cronbach’s Alpha. The reliability indices for A-tier, R-tier and B-tier are 0.69, 0.66 and 0.78, respectively. The values demonstrate that the instrument will produce a consistent result when it is employed over time.
The difficulty level index (P) ranges from 0 to 1 and represent the number of students answering the question correctly. The higher the difficulty level value, the higher the number of students answering the question correctly, and vice versa. Table 3 shows that the “moderate” category is the majority incident regarding the question’s difficulty level. On average, the P values for A-tier, R-tier and B-tier are 0.58, 0.53 and 0.42, respectively and fall in the “moderate” category. These values imply that the level of the questions is relevant for secondary school students.
Question | Answer-tier (A-tier) | Reason-tier (R-tier) | Both tier (B-tier) | |||
---|---|---|---|---|---|---|
P | Category | P | Category | P | Category | |
1. | 0.726 | Easy | 0.790 | Easy | 0.613 | Moderate |
2. | 0.742 | Easy | 0.565 | Moderate | 0.484 | Moderate |
3. | 0.516 | Moderate | 0.484 | Moderate | 0.435 | Moderate |
4. | 0.387 | Moderate | 0.435 | Moderate | 0.274 | Difficult |
5. | 0.581 | Moderate | 0.452 | Moderate | 0.419 | Moderate |
6. | 0.597 | Moderate | 0.339 | Moderate | 0.323 | Moderate |
7. | 0.677 | Moderate | 0.677 | Moderate | 0.645 | Moderate |
8. | 0.532 | Moderate | 0.419 | Moderate | 0.226 | Difficult |
9. | 0.468 | Moderate | 0.452 | Moderate | 0.435 | Moderate |
10. | 0.710 | Easy | 0.629 | Moderate | 0.548 | Moderate |
11. | 0.355 | Moderate | 0.726 | Easy | 0.306 | Difficult |
12. | 0.726 | Easy | 0.565 | Moderate | 0.484 | Moderate |
13. | 0.565 | Moderate | 0.306 | Moderate | 0.274 | Difficult |
The difficulty level of questions of the FTI-ENES.
Discriminatory index (D) compares the number of students answering the questions correctly between high achievement students and low achievement ones. The higher the D indices, the higher the number of students answering the question correctly from high achievement students, and vice versa (Table 4).
Question | A-tier | R-tier | B-tier | |||
---|---|---|---|---|---|---|
D | Category | D | Category | D | Category | |
1. | 0.765 | Excellent | 0.588 | Good | 0.647 | Good |
2. | 0.647 | Good | 0.529 | Good | 0.706 | Good |
3. | 0.647 | Good | 0.706 | Good | 0.706 | Good |
4. | 0.647 | Good | 0.412 | Good | 0.706 | Good |
5. | 0.529 | Good | 0.529 | Good | 0.529 | Good |
6. | 0.471 | Good | 0.471 | Good | 0.588 | Good |
7. | 0.529 | Good | 0.588 | Good | 0.765 | Excellent |
8. | 0.353 | Good | 0.471 | Good | 0.412 | Good |
9. | 0.588 | Good | 0.647 | Good | 0.471 | Good |
10. | 0.647 | Good | 0.765 | Excellent | 0.882 | Excellent |
11. | 0.353 | Good | 0.176 | Moderate | 0.471 | Good |
12. | 0.118 | Moderate | 0.647 | Good | 0.647 | Good |
13. | 0.588 | Good | 0.176 | Moderate | 0.526 | Good |
Discriminatory indices of questions of the FTI-ENES.
On average, the D values for A-tier, R-tier and B-tier are 0.53, 0.52 and 0.62, respectively and fall in the “moderate” category. These values imply that the instrument can differentiate students with high achievement and those with low achievement.
The distractor effectiveness parameter represents whether each wrong option in the A and R tiers is functional. An option is considered functional when it is chosen by at least one student [32]. Table 5 demonstrates that all the options are functional, implying the homogeneity of the options.
Question | ||||||||
---|---|---|---|---|---|---|---|---|
A | B | C | D | A | B | C | D | |
1. | 16.13 | 11.29 | 72.58 | 72.58 | 6.45 | 8.06 | 12.90 | |
2. | 11.29 | 74.19 | 14.52 | 12.90 | 22.58 | 8.06 | 56.45 | |
3. | 33.87 | 14.52 | 51.61 | 17.74 | 48.39 | 6.45 | 27.42 | |
4. | 38.71 | 45.16 | 16.13 | 32.26 | 19.35 | 41.94 | 6.45 | |
5. | 29.03 | 58.06 | 12.90 | 45.16 | 27.42 | 6.45 | 20.97 | |
6. | 59.68 | 17.74 | 22.58 | 20.97 | 19.35 | 25.81 | 33.87 | |
7. | 11.29 | 67.74 | 11.29 | 9.68 | 17.74 | 9.68 | 64.52 | 8.06 |
8. | 30.65 | 6.45 | 52.23 | 9.68 | 33.87 | 41.94 | 17.74 | 6.45 |
9. | 14.52 | 46.77 | 27.42 | 11.29 | 22.58 | 16.13 | 16.13 | 45.16 |
10. | 11.29 | 12.90 | 6.45 | 69.35 | 12.90 | 14.52 | 62.90 | 9.68 |
11. | 25.81 | 24.19 | 35.48 | 14.52 | 46.77 | 25.81 | 19.35 | 8.06 |
12. | 70.97 | 29.03 | 19.35 | 56.45 | 8.06 | 16.13 | ||
13. | 11.29 | 48.39 | 33.87 | 6.45 | 14.52 | 32.26 | 20.97 | 32.26 |
Distractor effectiveness for each option each question of the FTI-ENES.
A two-tier instrument that was initially developed by Treagust [15] is the pioneer of a multi-tier instrument. The next generation of multi-tier instruments, including three-tier, four-tier, and five-tier, responds to the drawbacks of the two-tier, which is the inability to distinguish an actual unscientific understanding and the role of guessing. We also believe that an additional drawing tier, as shown by the work of Anam et al. [28], is a rational exercise to be applied in future assessment purposes. By adopting the procedure of two-tier development, we suggest a more straightforward procedure to develop a multi-tier instrument including Mapping concept, Developing the multiple-choice question with free responses (MCQ-FR), Validating the MCQ-FR, Testing and Collecting Students’ Unscientific Understanding, Developing the prototype multi-tier instrument, and Validating the Prototype and refining the final multi-tier instrument. A wrong answer-wrong reason (WAWR) combination accompanied by a high confidence rating index (CRI) is the parameter to justify students’ unscientific understanding level. In this paper, we suggest employing a five scale CRI instead of 6 because it provides a better clarity of students to express his/her level of confidence. We also suggest that using a CRI of 3 as a limit between
The FTI-ENES instrument developed in this study consists of 13 questions covering the topic of electrolyte and non-electrolyte solutions. The instrument’s validity and reliability revealed that it is applicable to be used in identifying students’ understanding of electrolyte and non-electrolyte solution. Even though the scope of the concepts covered in this study is relevant for secondary chemistry school, it may also be transferable for fresh university students, particularly to identify their basic chemistry knowledge gained from their learning experiences in their secondary school chemistry. Other detailed examples of the application of this procedure in developing multi-tier instruments can be found in our previous works, including in chemical kinetics [7], acid–base properties of salt solution [33, 34], and thermochemistry [30].
We thank Directorate General Higher Education (Direktorat Jendral Pendidikan Tinggi, DIKTI), the Republic of Indonesia, for providing my PhD scholarship that contributes primarily to my multi-tier instrument project. We also thank Universitas Negeri Malang for providing a research grant through PNBP UM Scheme after finishing the PhD to continue my work in the multi-tier instrument area.
We can declare that there is no ‘conflict of interest’ in this paper.
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Their origins can be either natural or anthropogenic. The effects in regard to the time trends, vegetation, and soil will be reflected in the species distribution, forest composition, and soil potential productivity. In general, it can be said that the larger the fire and the shorter the time between two consecutive occurrences, the higher the probability to originate shifts in vegetation and soil degradation. In the Mediterranean region, the number of fire ignitions does not reflect the burnt area due to the occurrence of very large fires. The latter occur in a very small proportion of the number of ignitions, but result in very large burnt areas. Also there seems to be an increasing trend toward larger fires in the Mediterranean region due mainly to climatic and land use changes. This case study highlights the importance of vegetation regrowth a short time after the fire to maintain both forest systems and soil conservation.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Ana Cristina Gonçalves and Adélia M.O. Sousa",authors:[{id:"187880",title:"Prof.",name:"Adélia",middleName:null,surname:"Sousa",slug:"adelia-sousa",fullName:"Adélia Sousa"},{id:"194484",title:"Prof.",name:"Ana Cristina",middleName:null,surname:"Gonçalves",slug:"ana-cristina-goncalves",fullName:"Ana Cristina Gonçalves"}]},{id:"55867",doi:"10.5772/intechopen.69214",title:"The Marine Biodiversity of the Mediterranean Sea in a Changing Climate: The Impact of Biological Invasions",slug:"the-marine-biodiversity-of-the-mediterranean-sea-in-a-changing-climate-the-impact-of-biological-inva",totalDownloads:2355,totalCrossrefCites:9,totalDimensionsCites:19,abstract:"The Mediterranean Sea, one of the most complex marine ecosystems, is inhabited by a rich and diverse biota which is disproportionate to its dimensions. It is currently affected by different pressures, mainly driven by human activities such as climate change and bioinvasions. This Sea, also due to its geographic position (wedged between the temperate climate of central Europe and the arid climate of northern Africa), seems to be one of the regions most susceptible to global climate change. The increased rates of introduction and spread of marine alien species may represent a supplementary stress factor to Mediterranean marine native biota already challenged by climatic abnormalities. The Suez Canal is considered to be the main vector of introduction of non‐indigenous marine species into the Mediterranean Sea. Due to the dramatically accelerating rate of such introductions and due to the sheer magnitude of shipping traffic, the Mediterranean Sea may be considered as a true hotspot of marine bioinvasions. The complexity of interactions between native and invasive species and the associated resulting impacts make environmental management of such an issue particularly difficult. A collaboration between researchers, resource management agencies and policy makers is called for to bolster the effectiveness of invasive species management procedures.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Anna M. Mannino, Paolo Balistreri and Alan Deidun",authors:[{id:"202075",title:"Prof.",name:"Alan",middleName:null,surname:"Deidun",slug:"alan-deidun",fullName:"Alan Deidun"},{id:"203773",title:"Dr.",name:"Anna Maria",middleName:null,surname:"Mannino",slug:"anna-maria-mannino",fullName:"Anna Maria Mannino"},{id:"203777",title:"Dr.",name:"Paolo",middleName:null,surname:"Balistreri",slug:"paolo-balistreri",fullName:"Paolo Balistreri"}]},{id:"55480",doi:"10.5772/intechopen.69184",title:"Wheat: A Crop in the Bottom of the Mediterranean Diet Pyramid",slug:"wheat-a-crop-in-the-bottom-of-the-mediterranean-diet-pyramid",totalDownloads:1790,totalCrossrefCites:10,totalDimensionsCites:17,abstract:"Wheat currently provides 18% of the daily intake of calories and 20% of proteins for humans. Since its domestication in the Fertile Crescent, wheat has been the basic staple food of the major civilizations of Europe, West Asia and North Africa. The wheat-growing area within the Mediterranean Basin represents 27% of the arable land, and the region represents 60% of the world’s growing area for durum wheat, the species used for pasta manufacturing. Many changes have occurred from the low-productive plants cultivated in prehistoric times to the modern varieties that are now grown, which offer high productivity and quality standards. During the migration process of ancient forms of wheat from the east to the west of the Mediterranean Basin, both natural and human selections occurred, resulting in the development of local landraces characterized by their huge genetic diversity and their documented resilience to abiotic stresses. Wheat breeding activities conducted in the Mediterranean Basin during the twentieth century resulted in large genetic gains in yield and quality. New wheat varieties to be grown in the Mediterranean Basin will need to be resilient to climate change because more frequent episodes of higher temperatures and water scarcity are to be expected.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Conxita Royo, Jose Miguel Soriano and Fanny Alvaro",authors:[{id:"29324",title:"Dr.",name:"Conxita",middleName:null,surname:"Royo",slug:"conxita-royo",fullName:"Conxita Royo"},{id:"203525",title:"Dr.",name:"Jose Miguel",middleName:null,surname:"Soriano",slug:"jose-miguel-soriano",fullName:"Jose Miguel Soriano"},{id:"203526",title:"Dr.",name:"Fanny",middleName:null,surname:"Alvaro",slug:"fanny-alvaro",fullName:"Fanny Alvaro"}]},{id:"57227",doi:"10.5772/intechopen.70878",title:"Nutrient Cycling in the Mediterranean Sea: The Key to Understanding How the Unique Marine Ecosystem Functions and Responds to Anthropogenic Pressures",slug:"nutrient-cycling-in-the-mediterranean-sea-the-key-to-understanding-how-the-unique-marine-ecosystem-f",totalDownloads:1673,totalCrossrefCites:5,totalDimensionsCites:15,abstract:"The Mediterranean Sea is a marine desert: although it receives large nutrient inputs from a rapidly growing coastal population, its offshore waters exhibit extremely low biological productivity. Here, we use a mass balance modelling approach to analyse the sources and fate of the two main nutrients that support marine biomass production: phosphorus (P) and nitrogen (N). Surprisingly, the main source of P and N to the Mediterranean Sea is North Atlantic surface water entering through the Strait of Gibraltar, not emissions from surrounding land. The low biological productivity of the Mediterranean Sea is linked to the switch from less bioavailable nutrients entering the basin to highly bioavailable nutrients leaving it although similar amounts of total P and N enter and leave the Mediterranean Sea. This unique feature is a direct consequence of its unusual anti-estuarine circulation. An important environmental implication of the anti-estuarine circulation is that it efficiently removes excess anthropogenic nutrients entering the Mediterranean Sea, thus protecting offshore waters against eutrophication contrary to other semi-enclosed marine basins. In a similar vein, the “self-cleaning” nature of the Mediterranean Sea may prevent severe oxygen depletion of Mediterranean deep waters should ongoing climate warming lead to a weakening of the thermohaline circulation.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Helen R. Powley, Philippe Van Cappellen and Michael D. Krom",authors:[{id:"203160",title:"Prof.",name:"Michael",middleName:null,surname:"Krom",slug:"michael-krom",fullName:"Michael Krom"},{id:"203427",title:"Ms.",name:"Helen",middleName:null,surname:"Powley",slug:"helen-powley",fullName:"Helen Powley"},{id:"203428",title:"Prof.",name:"Phillippe",middleName:null,surname:"Van Cappellen",slug:"phillippe-van-cappellen",fullName:"Phillippe Van Cappellen"}]},{id:"55484",doi:"10.5772/intechopen.68948",title:"A Common Approach to Foster Prevention and Recovery of Forest Fires in Mediterranean Europe",slug:"a-common-approach-to-foster-prevention-and-recovery-of-forest-fires-in-mediterranean-europe",totalDownloads:1605,totalCrossrefCites:4,totalDimensionsCites:6,abstract:"Most countries of Mediterranean Europe are strongly affected by forest fires, with major socio-economic and environmental impacts that can spread over several regions and countries. A transnational approach allows creating synergies regarding resource sharing and problem-solving strategies. The access to high quality and up-to-date information is critical to improve fire hazard mitigation measures and promote comparable appraisals between different regions. Several collaborative initiatives have been implemented in Europe to foster research and service development, focusing on common issues amongst countries. The PREFER project was one of these initiatives, with the purpose of contributing to protect human communities and forests from fire hazard, by providing cartographic products through the implementation of a new systematic framework. The participation of end users, such as civil protection organizations and forest services, covering the Euro-Mediterranean region, was crucial to ensure the operational application of the mapping products. Fuel classification, daily fire hazard indices, vulnerability assessment and damage severity levels were some of the mapping applications developed for several test areas in Mediterranean Europe. This chapter illustrates the potential enhancements for forest fire management offered by this framework, bearing in mind the benefits of applying shared and harmonized approaches for common issues.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Sandra Oliveira, Giovanni Laneve, Lorenzo Fusilli, Georgios\nEftychidis, Adélia Nunes, Luciano Lourenço and Ana Sebastián-\nLópez",authors:[{id:"152339",title:"Prof.",name:"Luciano",middleName:null,surname:"Lourenço",slug:"luciano-lourenco",fullName:"Luciano Lourenço"},{id:"203745",title:"Dr.",name:"Sandra",middleName:null,surname:"Oliveira",slug:"sandra-oliveira",fullName:"Sandra Oliveira"},{id:"204131",title:"Prof.",name:"Giovanni",middleName:null,surname:"Laneve",slug:"giovanni-laneve",fullName:"Giovanni Laneve"},{id:"204132",title:"Dr.",name:"Lorenzo",middleName:null,surname:"Fusilli",slug:"lorenzo-fusilli",fullName:"Lorenzo Fusilli"},{id:"204133",title:"Mr.",name:"Georgios",middleName:null,surname:"Eftychidis",slug:"georgios-eftychidis",fullName:"Georgios Eftychidis"},{id:"204135",title:"Prof.",name:"Adélia",middleName:null,surname:"Nunes",slug:"adelia-nunes",fullName:"Adélia Nunes"},{id:"204136",title:"Dr.",name:"Ana",middleName:null,surname:"Sebastián-López",slug:"ana-sebastian-lopez",fullName:"Ana Sebastián-López"}]}],mostDownloadedChaptersLast30Days:[{id:"55745",title:"The Mediterranean: The Asian and African Roots of the Cradle of Civilization",slug:"the-mediterranean-the-asian-and-african-roots-of-the-cradle-of-civilization",totalDownloads:2769,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"In Antiquity, the regions encompassed by the Mediterranean Sea were extremely fertile allowing rapid prosperity. This wealth combined with the easy communication between banks contributed to a rich and successful transmission of knowledge, especially during the 1st millennium BC, which turned the Great Sea the core of Ancient History. Later, the Mediterranean civilization was acknowledged as the fundamental political, cultural, artistic and religious substratum for the construction of the so-called Western world. Yet, it was in Egypt and Mesopotamia, during the 4th and 3rd millennia BC that many of these foundations were first set. The Ancient Mediterranean world was not just influenced by its African and Asian neighbours but was in fact defined by a profound communion, at all levels, between these different regions. In the twenty-first century, however, many European countries still insist in portraying themselves as direct heirs of the combined Greco-Roman and Judeo-Christian traditions, disregarding their African and Asian roots. As a result of this flawed self-perception, a gap between Europe, Africa and Asia came to be, bearing deep consequences to the present. With this contribution, we aim to reclaim the importance of these other legacies to the construction of the cradle of the civilization.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Helena Trindade Lopes and Isabel Almeida",authors:[{id:"202246",title:"Prof.",name:"Helena",middleName:null,surname:"Trindade Lopes",slug:"helena-trindade-lopes",fullName:"Helena Trindade Lopes"},{id:"203967",title:"Prof.",name:"Isabel",middleName:null,surname:"Almeida",slug:"isabel-almeida",fullName:"Isabel Almeida"}]},{id:"55484",title:"A Common Approach to Foster Prevention and Recovery of Forest Fires in Mediterranean Europe",slug:"a-common-approach-to-foster-prevention-and-recovery-of-forest-fires-in-mediterranean-europe",totalDownloads:1604,totalCrossrefCites:4,totalDimensionsCites:6,abstract:"Most countries of Mediterranean Europe are strongly affected by forest fires, with major socio-economic and environmental impacts that can spread over several regions and countries. A transnational approach allows creating synergies regarding resource sharing and problem-solving strategies. The access to high quality and up-to-date information is critical to improve fire hazard mitigation measures and promote comparable appraisals between different regions. Several collaborative initiatives have been implemented in Europe to foster research and service development, focusing on common issues amongst countries. The PREFER project was one of these initiatives, with the purpose of contributing to protect human communities and forests from fire hazard, by providing cartographic products through the implementation of a new systematic framework. The participation of end users, such as civil protection organizations and forest services, covering the Euro-Mediterranean region, was crucial to ensure the operational application of the mapping products. Fuel classification, daily fire hazard indices, vulnerability assessment and damage severity levels were some of the mapping applications developed for several test areas in Mediterranean Europe. This chapter illustrates the potential enhancements for forest fire management offered by this framework, bearing in mind the benefits of applying shared and harmonized approaches for common issues.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Sandra Oliveira, Giovanni Laneve, Lorenzo Fusilli, Georgios\nEftychidis, Adélia Nunes, Luciano Lourenço and Ana Sebastián-\nLópez",authors:[{id:"152339",title:"Prof.",name:"Luciano",middleName:null,surname:"Lourenço",slug:"luciano-lourenco",fullName:"Luciano Lourenço"},{id:"203745",title:"Dr.",name:"Sandra",middleName:null,surname:"Oliveira",slug:"sandra-oliveira",fullName:"Sandra Oliveira"},{id:"204131",title:"Prof.",name:"Giovanni",middleName:null,surname:"Laneve",slug:"giovanni-laneve",fullName:"Giovanni Laneve"},{id:"204132",title:"Dr.",name:"Lorenzo",middleName:null,surname:"Fusilli",slug:"lorenzo-fusilli",fullName:"Lorenzo Fusilli"},{id:"204133",title:"Mr.",name:"Georgios",middleName:null,surname:"Eftychidis",slug:"georgios-eftychidis",fullName:"Georgios Eftychidis"},{id:"204135",title:"Prof.",name:"Adélia",middleName:null,surname:"Nunes",slug:"adelia-nunes",fullName:"Adélia Nunes"},{id:"204136",title:"Dr.",name:"Ana",middleName:null,surname:"Sebastián-López",slug:"ana-sebastian-lopez",fullName:"Ana Sebastián-López"}]},{id:"55076",title:"Drought-Forest Fire Relationships",slug:"drought-forest-fire-relationships",totalDownloads:1242,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"This study was carried out to determine the methods that bear the most realistic results in predicting the number of fires and burned area under the climate conditions in future. Different indices and statistical methods were used in predicting the burned area and the number of fires. With this aim, in addition to the indices used in estimating the climate, Machine Learning and multivariate adaptive regression spline (MARS) models are also used in predicting these factors. According to the results obtained in several studies, the relationship between the drought and fire indices burned area and the number of fires changes from region to region. While better results are obtained in predicting the burned area and the number of fires via the drought indices being used in this study and the MARS models that the combinations of these indices use, it is seen that a 30–39% success was achieved for predicting the amount of burned area via Machine Learning methods (Kernel Nearest Neighbor (kNN), Recursive Partitioning and Regression Trees (RPART), Support Vector Machine (SVM) and RF), and this success ranges widely from 8 to 41% in terms of the number of fires. RPART, of these four algorithms, performed the best in fire prediction, but kNN was the worst.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Tuğrul Varol, Mertol Ertuğrul and Halil Barış Özel",authors:[{id:"187966",title:"Dr.",name:"Halil Barış",middleName:null,surname:"Özel",slug:"halil-baris-ozel",fullName:"Halil Barış Özel"},{id:"203381",title:"Dr.",name:"Tugrul",middleName:null,surname:"Varol",slug:"tugrul-varol",fullName:"Tugrul Varol"},{id:"203760",title:"Dr.",name:"Mertol",middleName:null,surname:"Ertuğrul",slug:"mertol-ertugrul",fullName:"Mertol Ertuğrul"}]},{id:"55878",title:"How Landscapes Make Science: Italian National Narrative, The Great Mediterranean, and Giuseppe Sergi’s Biological Myth",slug:"how-landscapes-make-science-italian-national-narrative-the-great-mediterranean-and-giuseppe-sergi-s-",totalDownloads:1187,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The perception and representation of landscape are not natural facts but are cultural constructions of human agents. In this chapter, I aim at deconstructing the role of pre-classical archaeology of Eastern Mediterranean in the process of Italian nation building between the nineteenth and the twentieth centuries. In particular, I focus on how a substantial group of Italian intellectuals deployed archeological discoveries to construct the Mediterranean as a representational space, which eventually served as a platform for their nationalistic political discourses. To this end, I discuss the spreading of these new conceptions in the Italian cultural debate at large. A prominent figure in this debate was Giuseppe Sergi. By reconstructing his views on the connections between national identity and biology, I demonstrate the considerable performative effect of the Mediterranean as a symbolic space and source of meaning on Italian culture. Furthermore, I argue that this new role of the Mediterranean resulted from a negotiation between the archaeological discovery of pre-classical past and the political aspirations of those scholars who opposed Italian foreign and interior politics of the period.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Fedra A. Pizzato",authors:[{id:"203769",title:"Dr.",name:"Fedra Alessandra",middleName:null,surname:"Pizzato",slug:"fedra-alessandra-pizzato",fullName:"Fedra Alessandra Pizzato"}]},{id:"57009",title:"Deep-Sea Biodiversity in the Aegean Sea",slug:"deep-sea-biodiversity-in-the-aegean-sea",totalDownloads:1735,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The present chapter aims to describe macrofauna in the Aegean deep waters. The review is based mainly on the studies of deep waters below 200 m. A total of 386 species are included on the present checklist belonging to 9 phyla. Among these species, Porifera has 9 species, Cnidaria 4, Brachiopoda 3, Bryozoa 1, Polychaeta 34, Mollusca 92, Arthropoda 86, Echinodermata 30 and Pisces 127 species.",book:{id:"5995",slug:"mediterranean-identities-environment-society-culture",title:"Mediterranean Identities",fullTitle:"Mediterranean Identities - Environment, Society, Culture"},signatures:"Onur Gönülal and Cem Dalyan",authors:[{id:"204258",title:"Dr.",name:"Onur",middleName:null,surname:"Gönülal",slug:"onur-gonulal",fullName:"Onur Gönülal"},{id:"213770",title:"Dr.",name:"Cem",middleName:null,surname:"Dalyan",slug:"cem-dalyan",fullName:"Cem Dalyan"}]}],onlineFirstChaptersFilter:{topicId:"868",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:133,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"6",title:"Infectious Diseases",doi:"10.5772/intechopen.71852",issn:"2631-6188",scope:"This series will provide a comprehensive overview of recent research trends in various Infectious Diseases (as per the most recent Baltimore classification). Topics will include general overviews of infections, immunopathology, diagnosis, treatment, epidemiology, etiology, and current clinical recommendations for managing infectious diseases. Ongoing issues, recent advances, and future diagnostic approaches and therapeutic strategies will also be discussed. This book series will focus on various aspects and properties of infectious diseases whose deep understanding is essential for safeguarding the human race from losing resources and economies due to pathogens.",coverUrl:"https://cdn.intechopen.com/series/covers/6.jpg",latestPublicationDate:"June 25th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:13,editor:{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"3",title:"Bacterial Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/3.jpg",isOpenForSubmission:!1,annualVolume:null,editor:null,editorTwo:null,editorThree:null},{id:"4",title:"Fungal Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/4.jpg",isOpenForSubmission:!0,annualVolume:11400,editor:{id:"174134",title:"Dr.",name:"Yuping",middleName:null,surname:"Ran",slug:"yuping-ran",fullName:"Yuping Ran",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9d6QAC/Profile_Picture_1630330675373",biography:"Dr. Yuping Ran, Professor, Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China. Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. Board Member and Chair of Mycology Group of Chinese Society of Dermatology.",institutionString:null,institution:{name:"Sichuan University",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null},{id:"5",title:"Parasitic Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",isOpenForSubmission:!0,annualVolume:11401,editor:{id:"67907",title:"Dr.",name:"Amidou",middleName:null,surname:"Samie",slug:"amidou-samie",fullName:"Amidou Samie",profilePictureURL:"https://mts.intechopen.com/storage/users/67907/images/system/67907.jpg",biography:"Dr. Amidou Samie is an Associate Professor of Microbiology at the University of Venda, in South Africa, where he graduated for his PhD in May 2008. He joined the Department of Microbiology the same year and has been giving lectures on topics covering parasitology, immunology, molecular biology and industrial microbiology. He is currently a rated researcher by the National Research Foundation of South Africa at category C2. He has published widely in the field of infectious diseases and has overseen several MSc’s and PhDs. His research activities mostly cover topics on infectious diseases from epidemiology to control. His particular interest lies in the study of intestinal protozoan parasites and opportunistic infections among HIV patients as well as the potential impact of childhood diarrhoea on growth and child development. He also conducts research on water-borne diseases and water quality and is involved in the evaluation of point-of-use water treatment technologies using silver and copper nanoparticles in collaboration with the University of Virginia, USA. 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His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. 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She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",institutionURL:null,country:{name:"Turkey"}}}]},{type:"book",id:"7139",title:"Current Approaches in Orthodontics",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7139.jpg",slug:"current-approaches-in-orthodontics",publishedDate:"April 10th 2019",editedByType:"Edited by",bookSignature:"Belma Işık Aslan and Fatma Deniz Uzuner",hash:"2c77384eeb748cf05a898d65b9dcb48a",volumeInSeries:2,fullTitle:"Current Approaches in Orthodontics",editors:[{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null}]},{type:"book",id:"7572",title:"Trauma in Dentistry",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7572.jpg",slug:"trauma-in-dentistry",publishedDate:"July 3rd 2019",editedByType:"Edited by",bookSignature:"Serdar Gözler",hash:"7cb94732cfb315f8d1e70ebf500eb8a9",volumeInSeries:3,fullTitle:"Trauma in Dentistry",editors:[{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",institutionURL:null,country:{name:"Turkey"}}}]},{type:"book",id:"7060",title:"Gingival Disease",subtitle:"A Professional Approach for Treatment and Prevention",coverURL:"https://cdn.intechopen.com/books/images_new/7060.jpg",slug:"gingival-disease-a-professional-approach-for-treatment-and-prevention",publishedDate:"October 23rd 2019",editedByType:"Edited by",bookSignature:"Alaa Eddin Omar Al Ostwani",hash:"b81d39988cba3a3cf746c1616912cf41",volumeInSeries:4,fullTitle:"Gingival Disease - A Professional Approach for Treatment and Prevention",editors:[{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. He is also a Member of the Reviewer Board of International Journal of Dental Medicine (IJDM), and the Indian Journal of Conservative and Endodontics since 2016.",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",institutionURL:null,country:{name:"India"}}}]}]},openForSubmissionBooks:{paginationCount:3,paginationItems:[{id:"11570",title:"Influenza - New Approaches",coverURL:"https://cdn.intechopen.com/books/images_new/11570.jpg",hash:"157b379b9d7a4bf5e2cc7a742f155a44",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"May 10th 2022",isOpenForSubmission:!0,editors:[{id:"139889",title:"Dr.",name:"Seyyed Shamsadin",surname:"Athari",slug:"seyyed-shamsadin-athari",fullName:"Seyyed Shamsadin Athari"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11569",title:"Bacterial Sexually Transmitted Infections - New Findings, Diagnosis, Treatment, and Prevention",coverURL:"https://cdn.intechopen.com/books/images_new/11569.jpg",hash:"069d6142ecb0d46d14920102d48c0e9d",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"May 31st 2022",isOpenForSubmission:!0,editors:[{id:"189561",title:"Dr.",name:"Mihaela Laura",surname:"Vica",slug:"mihaela-laura-vica",fullName:"Mihaela Laura Vica"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11568",title:"Staphylococcal Infections - Recent Advances and Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11568.jpg",hash:"92c881664d1921c7f2d0fee34b78cd08",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"July 8th 2022",isOpenForSubmission:!0,editors:[{id:"59719",title:"Dr.",name:"Jaime",surname:"Bustos-Martínez",slug:"jaime-bustos-martinez",fullName:"Jaime Bustos-Martínez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:10,paginationItems:[{id:"82380",title:"Evolution of Parasitism and Pathogenic Adaptations in Certain Medically Important Fungi",doi:"10.5772/intechopen.105206",signatures:"Gokul Shankar Sabesan, Ranjit Singh AJA, Ranjith Mehenderkar and Basanta Kumar Mohanty",slug:"evolution-of-parasitism-and-pathogenic-adaptations-in-certain-medically-important-fungi",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fungal Infectious Diseases - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11400.jpg",subseries:{id:"4",title:"Fungal Infectious Diseases"}}},{id:"82367",title:"Spatial Variation and Factors Associated with Unsuppressed HIV Viral Load among Women in an HIV Hyperendemic Area of KwaZulu-Natal, South Africa",doi:"10.5772/intechopen.105547",signatures:"Adenike O. 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He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. Govindarajan completed his BSc degree in Zoology at Government Arts College (Autonomous), Kumbakonam, and MSc, MPhil, and PhD degrees at Annamalai University, Annamalai Nagar, Tamil Nadu, India. He is serving as an assistant professor at the Department of Zoology, Annamalai University. His research interests include isolation, identification, and characterization of biologically active molecules from plants and microbes. He has identified more than 20 pure compounds with high mosquitocidal activity and also conducted high-quality research on photochemistry and nanosynthesis. He has published more than 150 studies in journals with impact factor and 2 books in Lambert Academic Publishing, Germany. He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"337446",title:"Dr.",name:"Maria",middleName:null,surname:"Zavala-Colon",slug:"maria-zavala-colon",fullName:"Maria Zavala-Colon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico, Medical Sciences Campus",country:{name:"United States of America"}}},{id:"338856",title:"Mrs.",name:"Nur Alvira",middleName:null,surname:"Pascawati",slug:"nur-alvira-pascawati",fullName:"Nur Alvira Pascawati",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universitas Respati Yogyakarta",country:{name:"Indonesia"}}},{id:"441116",title:"Dr.",name:"Jovanka M.",middleName:null,surname:"Voyich",slug:"jovanka-m.-voyich",fullName:"Jovanka M. Voyich",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Montana State University",country:{name:"United States of America"}}},{id:"330412",title:"Dr.",name:"Muhammad",middleName:null,surname:"Farhab",slug:"muhammad-farhab",fullName:"Muhammad Farhab",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"349495",title:"Dr.",name:"Muhammad",middleName:null,surname:"Ijaz",slug:"muhammad-ijaz",fullName:"Muhammad Ijaz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}}]}},subseries:{item:{id:"4",type:"subseries",title:"Fungal Infectious Diseases",keywords:"Emerging Fungal Pathogens, Invasive Infections, Epidemiology, Cell Membrane, Fungal Virulence, Diagnosis, Treatment",scope:"Fungi are ubiquitous and there are almost no non-pathogenic fungi. Fungal infectious illness prevalence and prognosis are determined by the exposure between fungi and host, host immunological state, fungal virulence, and early and accurate diagnosis and treatment. \r\nPatients with both congenital and acquired immunodeficiency are more likely to be infected with opportunistic mycosis. Fungal infectious disease outbreaks are common during the post- disaster rebuilding era, which is characterised by high population density, migration, and poor health and medical conditions.\r\nSystemic or local fungal infection is mainly associated with the fungi directly inhaled or inoculated in the environment during the disaster. The most common fungal infection pathways are human to human (anthropophilic), animal to human (zoophilic), and environment to human (soilophile). Diseases are common as a result of widespread exposure to pathogenic fungus dispersed into the environment. \r\nFungi that are both common and emerging are intertwined. In Southeast Asia, for example, Talaromyces marneffei is an important pathogenic thermally dimorphic fungus that causes systemic mycosis. Widespread fungal infections with complicated and variable clinical manifestations, such as Candida auris infection resistant to several antifungal medicines, Covid-19 associated with Trichoderma, and terbinafine resistant dermatophytosis in India, are among the most serious disorders. \r\nInappropriate local or systemic use of glucocorticoids, as well as their immunosuppressive effects, may lead to changes in fungal infection spectrum and clinical characteristics. Hematogenous candidiasis is a worrisome issue that affects people all over the world, particularly ICU patients. CARD9 deficiency and fungal infection have been major issues in recent years. Invasive aspergillosis is associated with a significant death rate. Special attention should be given to endemic fungal infections, identification of important clinical fungal infections advanced in yeasts, filamentous fungal infections, skin mycobiome and fungal genomes, and immunity to fungal infections.\r\nIn addition, endemic fungal diseases or uncommon fungal infections caused by Mucor irregularis, dermatophytosis, Malassezia, cryptococcosis, chromoblastomycosis, coccidiosis, blastomycosis, histoplasmosis, sporotrichosis, and other fungi, should be monitored. \r\nThis topic includes the research progress on the etiology and pathogenesis of fungal infections, new methods of isolation and identification, rapid detection, drug sensitivity testing, new antifungal drugs, schemes and case series reports. It will provide significant opportunities and support for scientists, clinical doctors, mycologists, antifungal drug researchers, public health practitioners, and epidemiologists from all over the world to share new research, ideas and solutions to promote the development and progress of medical mycology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/4.jpg",hasOnlineFirst:!0,hasPublishedBooks:!1,annualVolume:11400,editor:{id:"174134",title:"Dr.",name:"Yuping",middleName:null,surname:"Ran",slug:"yuping-ran",fullName:"Yuping Ran",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9d6QAC/Profile_Picture_1630330675373",biography:"Dr. Yuping Ran, Professor, Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China. Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. 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Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"June 29th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:4,numberOfPublishedChapters:318,numberOfPublishedBooks:32,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"14",title:"Cell and Molecular Biology",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",annualVolume:11410,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",annualVolume:11411,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null,editorialBoard:[{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",fullName:"Abdulsamed Kükürt",profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",institutionString:null,institution:{name:"Kafkas University",institutionURL:null,country:{name:"Turkey"}}},{id:"241413",title:"Dr.",name:"Azhar",middleName:null,surname:"Rasul",fullName:"Azhar Rasul",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRT1oQAG/Profile_Picture_1635251978933",institutionString:null,institution:{name:"Government College University, Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"178316",title:"Ph.D.",name:"Sergey",middleName:null,surname:"Sedykh",fullName:"Sergey Sedykh",profilePictureURL:"https://mts.intechopen.com/storage/users/178316/images/system/178316.jfif",institutionString:null,institution:{name:"Novosibirsk State University",institutionURL:null,country:{name:"Russia"}}}]},{id:"17",title:"Metabolism",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",annualVolume:11413,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},{id:"18",title:"Proteomics",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://mts.intechopen.com/storage/users/81926/images/system/81926.png",institutionString:"Suez Canal University",institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/10824",hash:"",query:{},params:{id:"10824"},fullPath:"/chapters/10824",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var t;(t=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(t)}()