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Thrombophilia
Edited by Andrea Luigi Tranquilli, ISBN 978-953-307-872-4, Hard cover, 226 pages, Publisher: InTech, Published: November 09, 2011 under CC BY 3.0 license, in subject Hematology
DOI: 10.5772/1329
Thrombophilia(s) is a condition of increased tendency to form blood clots. This condition may be inherited or acquired, and this is why the term is often used in plural. People who have thrombophilia are at greater risk of having thromboembolic complications, such as deep venous thrombosis, pulmonary embolism or cardiovascular complications, like stroke or myocardial infarction, nevertheless those complications are rare and it is possible that those individuals will never encounter clotting problems in their whole life. The enhanced blood coagulability is exacerbated under conditions of prolonged immobility, surgical interventions and most of all during pregnancy and puerperium, and the use of estrogen contraception. This is the reason why many obstetricians-gynecologysts became involved in this field aside the hematologists: women are more frequently at risk. The availability of new lab tests for hereditary thrombophilia(s) has opened a new era with reflections on epidemiology, primary healthcare, prevention and prophylaxis, so that thrombophilia is one of the hottest topics in contemporary medicine.
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Book contents
- Chapter 1Inherited Thrombophilia: Past, Present, and Future Research
- Chapter 2Association of Haemostasis Activation Markers with Thrombophilia and Venous Thromboembolism
- Chapter 3Geographic and Ethnic Differences in the Prevalence of Thrombophilia
- Chapter 4Inherited Thrombophilia and the Risk of Vascular Events
- Chapter 5APC Resistance
- Chapter 6Inherited and Acquired Thrombophilia in Pregnancy
- Chapter 7The Impact of Inherited Thrombophilia on Placental Haemostasis and Adverse Pregnancy Outcomes
- Chapter 8Infertility and Inherited Thrombophilia
- Chapter 9Thrombophilia and Recurrent Pregnancy Loss
- Chapter 10Pathogenic Mechanisms of Thrombosis in Antiphospholipid Syndrome (APS)
- Chapter 11Adverse Pregnancy Outcome in Antiphospholipid Antibodies Syndrome: Pathogenic Mechanisms and Clinical Management
- Chapter 12Fetal Thrombophilia
