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This book is indexed in
Medicine » Medical Genetics
Targets in Gene Therapy
Edited by Yongping You, ISBN 978-953-307-540-2, Hard cover, 436 pages, Publisher: InTech, Chapters published August 23, 2011 under CC BY-NC-SA 3.0 license
DOI: 10.5772/1012
This book aims at providing an up-to-date report to cover key aspects of existing problems in the emerging field of targets in gene therapy. With the contributions in various disciplines of gene therapy, the book brings together major approaches: Target Strategy in Gene Therapy, Gene Therapy of Cancer and Gene Therapy of Other Diseases. This source enables clinicians and researchers to select and effectively utilize new translational approaches in gene therapy and analyze the developments in target strategy in gene therapy.
- Chapter 1
Choosing Targets for Gene Therapy - Chapter 2
Gene Modulation by Peptide Nucleic Acids (PNAs) Targeting microRNAs (miRs) - Chapter 3
Effective Transgene Constructs to Enhance Gene Therapy with Trichostatin A - Chapter 4
Suicide Gene Therapy by Herpes Simplex Virus-1 Thymidine Kinase (HSV-TK) - Chapter 5
Translational Challenges for Hepatocyte-Directed Gene Transfer - Chapter 6
Physiologically-Regulated Expression Vectors for Gene Therapy - Chapter 7
PLP-Dependent Enzymes: a Potent Therapeutic Approach for Cancer and Cardiovascular Diseases - Chapter 8
Improvement of FasL Gene Therapy In Vitro by Fusing the FasL to Del1 Protein Domains - Chapter 9
Feasibility of BMP-2 Gene Therapy Using an Ultra-Fine Needle - Chapter 10
Current Strategies for Cancer Gene Therapy - Chapter 11
Gene Therapy Strategy for Tumour Hypoxia - Chapter 12
Gene Therapy of Glioblastoma: Anti – Gene Anti IGF-I Strategy - Chapter 13
Mechanism of Hypoxia-Inducible Factor-1alpha Over- Expression and Molecular-Target Therapy for Hepatocellular Carcinoma - Chapter 14
Cancer Gene Therapy via NKG2D and FAS Pathways - Chapter 15
Emergence of IFN-lambda as a Potential Antitumor Agent - Chapter 16
Intramuscular IL-12 Electrogene Therapy for Treatment of Spontaneous Canine Tumors - Chapter 17
Gene Therapy Targets and the Role of Pharmacogenomics in Heart Failure - Chapter 18
Gene Therapy of the Heart through Targeting Non-Cardiac Cells - Chapter 19
Transplantation of Sendai Viral Angiopoietin-1-Modified Mesenchymal Stem Cells for Ischemic Heart Disease - Chapter 20
Using Factor VII in Hemophilia Gene Therapy - Chapter 21
The Different Effects of TGF-β1, VEGF and PDGF on the Remodeling of Anterior Cruciate Ligament Graft - Chapter 22
Different ex Vivo and Direct in Vivo DNA Administration Strategies for Growth Hormone Gene Therapy in Dwarf Animals - Chapter 23
Protection from Lethal Cell Death in Cecal Ligation and Puncture-Induced Sepsis Mouse Model by In Vivo Delivery of FADD siRNA - Chapter 24
Muscle-Targeted Gene Therapy of Charcot Marie-Tooth Disease is Dependent on Muscle Activity


