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Biochemistry, Genetics and Molecular Biology
Protein Interactions
Edited by Jianfeng Cai and Rongsheng E. Wang, ISBN 978-953-51-0244-1, Hard cover, 464 pages, Publisher: InTech, Chapters published March 16, 2012 under CC BY 3.0 license
DOI: 10.5772/2336
Protein interactions, which include interactions between proteins and other biomolecules, are essential to all aspects of biological processes, such as cell growth, differentiation, and apoptosis. Therefore, investigation and modulation of protein interactions are of significance as it not only reveals the mechanism governing cellular activity, but also leads to potential agents for the treatment of various diseases. The objective of this book is to highlight some of the latest approaches in the study of protein interactions, including modulation of protein interactions, development of analytical techniques, etc. Collectively they demonstrate the importance and the possibility for the further investigation and modulation of protein interactions as technology is evolving.
- Chapter 1
MOZ-TIF2 Fusion Protein Binds to Histone Chaperon Proteins CAF-1A and ASF1B Through Its MOZ Portion - Chapter 2
Autophagy-Mediated Defense Response of Mouse Mesenchymal Stromal Cells (MSCs) to Challenge with Escherichia coli - Chapter 3
The Use of Reductive Methylation of Lysine Residues to Study Protein-Protein Interactions in High Molecular Weight Complexes by Solution NMR - Chapter 4
Regulation of Protein-Protein Interactions by the SUMO and Ubiquitin Pathways - Chapter 5
Functional Protein Interactions in Steroid Receptor-Chaperone Complexes - Chapter 6
The TPR Motif as a Protein Interaction Module - A Discussion of Structure and Function - Chapter 7
The Two DUF642 At5g11420 and At4g32460-Encoded Proteins Interact In Vitro with the AtPME3 Catalytic Domain - Chapter 8
Protein-Protein Interactions and Disease - Chapter 9
AApeptides as a New Class of Peptidomimetics to Regulate Protein-Protein Interactions - Chapter 10
Protein Interactions in S-RNase-Based Gametophytic Self-Incompatibility - Chapter 11
Direct Visualization of Single-Molecule DNA-Binding Proteins Along DNA to Understand DNA-Protein Interactions - Chapter 12
Defining the Cellular Interactome of Disease-Linked Proteins in Neurodegeneration - Chapter 13
Biochemical, Structural and Pathophysiological Aspects of Prorenin and (Pro)renin Receptor - Chapter 14
Cholesterol-Binding Peptides and Phagocytosis - Chapter 15
One-by-One Sample Preparation Method for Protein Network Analysis - Chapter 16
Live In-Cell Visualization of Proteins Using Super Resolution Imaging - Chapter 17
Approaches to Analyze Protein-Protein Interactions of Membrane Proteins - Chapter 18
Relating Protein Structure and Function Through a Bijection and Its Implications on Protein Structure Prediction - Chapter 19
Protein-DNA Interactions Studies with Single Tethered Molecule Techniques - Chapter 20
Characterization of Protein-Protein Interactions via Static and Dynamic Light Scattering - Chapter 21
Site-Directed Spin Labeling and Electron Paramagnetic Resonance (EPR) Spectroscopy: A Versatile Tool to Study Protein-Protein Interactions - Chapter 22
Modification, Development, Application and Prospects of Tandem Affinity Purification Method

